The University of Queensland

A method for prostate and breast cancer cell spheroid cultures using gelatin methacryloyl-based hydrogels

Meinert, Christoph, Theodoropoulos, Christina, Klein, Travis J., Hutmacher, Dietmar W. and Loessner, Daniela (2018). A method for prostate and breast cancer cell spheroid cultures using gelatin methacryloyl-based hydrogels. Prostate cancer. (pp. 175-194) edited by Zoran Culig. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-7845-8_10

6.7 Synovial joints: Mechanobiology and tissue engineering of articular cartilage and synovial fluid

Raleigh, A. R., McCarty, W.J., Chen, A. C., Meinert, C., Klein, T. J. and Sah, R. L. (2017). 6.7 Synovial joints: Mechanobiology and tissue engineering of articular cartilage and synovial fluid. Comprehensive Biomaterials II. (pp. 107-134) Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-803581-8.09304-8

Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells

So, Choon Leng, Meinert, Christoph, Xia, Qing, Robitaille, Mélanie, Roberts-Thomson, Sarah J and Monteith, Gregory R (2022). Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells. Cell Calcium, 104 102569, 102569. doi: 10.1016/j.ceca.2022.102569

In vitro and in vivo investigation of a zonal microstructured scaffold for osteochondral defect repair

Steele, Joseph A.M., Moore, Axel C., St-Pierre, Jean-Philippe, McCullen, Seth D., Gormley, Adam J., Horgan, Conor C., Black, Cameron RM., Meinert, Christoph, Klein, Travis, Saifzadeh, Siamak, Steck, Roland, Ren, Jiongyu, Woodruff, Maria A. and Stevens, Molly M. (2022). In vitro and in vivo investigation of a zonal microstructured scaffold for osteochondral defect repair. Biomaterials, 286 121548, 121548. doi: 10.1016/j.biomaterials.2022.121548

Biofabrication of small diameter tissue-engineered vascular grafts

Weekes, Angus, Bartnikowski, Nicole, Pinto, Nigel, Jenkins, Jason, Meinert, Christoph and Klein, Travis J. (2022). Biofabrication of small diameter tissue-engineered vascular grafts. Acta Biomaterialia, 138, 92-111. doi: 10.1016/j.actbio.2021.11.012

Gelatin methacryloyl hydrogels for the localized delivery of Cefazolin

Vigata, Margaux, O’Connell, Cathal D., Cometta, Silvia, Hutmacher, Dietmar W., Meinert, Christoph and Bock, Nathalie (2021). Gelatin methacryloyl hydrogels for the localized delivery of Cefazolin. Polymers, 13 (22) 3960. doi: 10.3390/polym13223960

RASSF1A suppression as a potential regulator of mechano-pathobiology associated with mammographic density in BRCA mutation Carriers

Reye, Gina, Huang, Xuan, Britt, Kara L., Meinert, Christoph, Blick, Tony, Xu, Yannan, Momot, Konstantin I., Lloyd, Thomas, Northey, Jason J., Thompson, Erik W. and Hugo, Honor J. (2021). RASSF1A suppression as a potential regulator of mechano-pathobiology associated with mammographic density in BRCA mutation Carriers. Cancers, 13 (13) 3251, 1-16. doi: 10.3390/cancers13133251

Deciphering the molecular mechanism of water interaction with gelatin methacryloyl hydrogels: role of ionic strength, pH, drug loading and hydrogel network characteristics

Vigata, Margaux, Meinert, Christoph, Bock, Nathalie, Dargaville, Bronwin L. and Hutmacher, Dietmar W. (2021). Deciphering the molecular mechanism of water interaction with gelatin methacryloyl hydrogels: role of ionic strength, pH, drug loading and hydrogel network characteristics. Biomedicines, 9 (5), 574. doi: 10.3390/biomedicines9050574

Automated 3D microphysiometry facilitates high-content and highly reproducible oxygen measurements within 3D cell culture models

Eggert, Sebastian, Gutbrod, Martin S., Liebsch, Gregor, Meier, Robert, Meinert, Christoph and Hutmacher, Dietmar W. (2021). Automated 3D microphysiometry facilitates high-content and highly reproducible oxygen measurements within 3D cell culture models. ACS Sensors, 6 (3) acssensors.0c02551, 1248-1260. doi: 10.1021/acssensors.0c02551

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo

Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas and McGovern, Jacqui A. (2020). Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo. Bone Research, 8 (1) 17, 17. doi: 10.1038/s41413-020-0092-5

Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques

Vigata, Margaux, Meinert, Christoph, Hutmacher, Dietmar W. and Bock, Nathalie (2020). Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques. Pharmaceutics, 12 (12) 1188, 1-45. doi: 10.3390/pharmaceutics12121188

OpenWorkstation: A modular open-source technology for automated in vitro workflows

Eggert, Sebastian, Mieszczanek, Pawel, Meinert, Christoph and Hutmacher, Dietmar W. (2020). OpenWorkstation: A modular open-source technology for automated in vitro workflows. HardwareX, 8 e00152, e00152. doi: 10.1016/j.ohx.2020.e00152

Gelatin Methacryloyl Hydrogels Control the Localized Delivery of Albumin-Bound Paclitaxel

Vigata, Margaux, Meinert, Christoph, Pahoff, Stephen, Bock, Nathalie and Hutmacher, Dietmar W. (2020). Gelatin Methacryloyl Hydrogels Control the Localized Delivery of Albumin-Bound Paclitaxel. Polymers, 12 (2), 501. doi: 10.3390/polym12020501

Type II Photoinitiator and Tuneable Poly(Ethylene Glycol)-Based Materials Library for Visible Light Photolithography

Yang, Xin, Mohseni, Mina, Bas, Onur, Meinert, Christoph, New, Elizabeth J. and Castro, Nathan J. (2020). Type II Photoinitiator and Tuneable Poly(Ethylene Glycol)-Based Materials Library for Visible Light Photolithography. Tissue Engineering Part A, 26 (5-6), 292-304. doi: 10.1089/ten.tea.2019.0282

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo

Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas and McGovern, Jacqui A. (2019). Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo. Bone Research, 7 (1) 31, 31. doi: 10.1038/s41413-019-0072-9

Immunogold FIB-SEM: combining volumetric ultrastructure visualization with 3D biomolecular analysis to dissect cell-environment interactions

Gopal, Sahana, Chiappini, Ciro, Armstrong, James P. K., Chen, Qu, Serio, Andrea, Hsu, Chia-Chen, Meinert, Christoph, Klein, Travis J., Hutmacher, Dietmar W., Rothery, Stephen and Stevens, Molly M. (2019). Immunogold FIB-SEM: combining volumetric ultrastructure visualization with 3D biomolecular analysis to dissect cell-environment interactions. Advanced Materials, 31 (32), 1-8. doi: 10.1002/adma.201900488

Effect of gelatin source and photoinitiator type on chondrocyte redifferentiation in gelatin methacryloyl-based tissue-engineered cartilage constructs

Pahoff, Stephen, Meinert, Christoph, Bas, Onur, Nguyen, Long, Klein, Travis J. and Hutmacher, Dietmar W. (2019). Effect of gelatin source and photoinitiator type on chondrocyte redifferentiation in gelatin methacryloyl-based tissue-engineered cartilage constructs. Journal of Materials Chemistry B, 7 (10), 1761-1772. doi: 10.1039/c8tb02607f

Optimization of 3D bioprinting of periodontal ligament cells

Thattaruparambil Raveendran, Nimal, Vaquette, Cédryck, Meinert, Christoph, Samuel Ipe, Deepak and Ivanovski, Saso (2019). Optimization of 3D bioprinting of periodontal ligament cells. Dental Materials, 35 (12), 1683-1694. doi: 10.1016/j.dental.2019.08.114

Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression

Murekatete, Berline, Shokoohmand, Ali, McGovern, Jacqui, Mohanty, Lipsa, Meinert, Christoph, Hollier, Brett G., Zippelius, Alfred, Upton, Zee and Kashyap, Abhishek S. (2018). Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression. Scientific Reports, 8 (1) 583. doi: 10.1038/s41598-017-19073-4

Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone

McGovern, Jacqui A., Shafiee, Abbas, Wagner, Ferdinand, Lahr, Christoph A., Landgraf, Marietta, Meinert, Christoph, Williams, Elizabeth D., Russell, Pamela J., Clements, Judith A., Loessner, Daniela, Holzapfel, Boris M., Risbridger, Gail P. and Hutmacher, Dietmar W. (2018). Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone. Cancers, 10 (11) 438, 438. doi: 10.3390/cancers10110438

Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning

Armstrong, James P. K., Puetzer, Jennifer L., Serio, Andrea, Guex, Anne Geraldine, Kapnisi, Michaella, Breant, Alexandre, Zong, Yifan, Assal, Valentine, Skaalure, Stacey C., King, Oisin, Murty, Tara, Meinert, Christoph, Franklin, Amanda C., Bassindale, Philip G., Nichols, Madeleine K., Terracciano, Cesare M., Hutmacher, Dietmar W., Drinkwater, Bruce W., Klein, Travis J., Perriman, Adam W. and Stevens, Molly M. (2018). Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning. Advanced Materials, 30 (43), 1802649. doi: 10.1002/adma.201802649

Rational design and fabrication of multiphasic soft network composites for tissue engineering articular cartilage: a numerical model-based approach

Bas, Onur, Lucarotti, Sara, Angella, Davide D., Castro, Nathan J., Meinert, Christoph, Wunner, Felix M., Rank, Ernst, Vozzi, Giovanni, Klein, Travis J., Catelas, Isabelle, De-Juan-Pardo, Elena M. and Hutmacher, Dietmar W. (2018). Rational design and fabrication of multiphasic soft network composites for tissue engineering articular cartilage: a numerical model-based approach. Chemical Engineering Journal, 340, 15-23. doi: 10.1016/j.cej.2018.01.020

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study

Shafiee, Abbas, McGovern, Jacqui A., Lahr, Christoph A., Meinert, Christoph, Moi, Davide, Wagner, Ferdinand, Landgraf, Marietta, De-Juan-Pardo, Elena, Mazzieri, Roberta and Hutmacher, Dietmar W. (2018). Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study. International Journal of Cancer, 143 (6), 1470-1482. doi: 10.1002/ijc.31528

A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage

Meinert, Christoph, Schrobback, Karsten, Hutmacher, Dietmar W. and Klein, Travis J. (2017). A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage. Scientific Reports, 7 (1) 16997, 1-14. doi: 10.1038/s41598-017-16523-x

Biofabricated soft network composites for cartilage tissue engineering

Bas, Onur, De-Juan-Pardo, Elena M., Meinert, Christoph, D'Angella, Davide, Baldwin, Jeremy G., Bray, Laura J., Wellard, R. Mark, Kollmannsberger, Stefan, Rank, Ernst, Werner, Carsten, Klein, Travis J., Catelas, Isabelle and Hutmacher, Dietmar W. (2017). Biofabricated soft network composites for cartilage tissue engineering. Biofabrication, 9 (2). doi: 10.1088/1758-5090/aa6b15

Current developments in multifunctional smart materials for 3D/4D bioprinting

Castro, Nathan J., Meinert, Christoph, Levett, Peter and Hutmacher, Dietmar W. (2017). Current developments in multifunctional smart materials for 3D/4D bioprinting. Current Opinion in Biomedical Engineering, 2, 67-75. doi: 10.1016/j.cobme.2017.04.002

Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models

McGovern, J. A., Meinert, C., de Veer, S. J., Hollier, B. G., Parker, T. J. and Upton, Z. (2017). Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models. British Journal of Dermatology, 176 (1), 145-158. doi: 10.1111/bjd.14879

Functionalization, preparation and use of cell-laden gelatin methacryloyl-based hydrogels as modular tissue culture platforms

Loessner, Daniela, Meinert, Christoph, Kaemmerer, Elke, Martine, Laure C., Yue, Kan, Levett, Peter A., Klein, Travis J., Melchels, Ferry P. W., Khademhosseini, Ali and Hutmacher, Dietmar W. (2016). Functionalization, preparation and use of cell-laden gelatin methacryloyl-based hydrogels as modular tissue culture platforms. Hepatitis Monthly, 11 (4), 727-746. doi: 10.1038/nprot.2016.037

Effect of Preculture and Loading on Expression of Matrix Molecules, Matrix Metalloproteinases, and Cytokines by Expanded Osteoarthritic Chondrocytes

Jeon, June E., Schrobback, Karsten, Meinert, Christoph, Sramek, Viviana, Hutmacher, Dietmar W. and Klein, Travis J. (2013). Effect of Preculture and Loading on Expression of Matrix Molecules, Matrix Metalloproteinases, and Cytokines by Expanded Osteoarthritic Chondrocytes. Arthritis and Rheumatism, 65 (9), 2356-2367. doi: 10.1002/art.38049

Tailoring hydrogel surface properties to modulate cellular response to shear loading

Meinert, Christoph, Schrobback, Karsten, Levett, Peter A., Lutton, Cameron, Sah, Robert L. and Klein, Travis J. (2017). Tailoring hydrogel surface properties to modulate cellular response to shear loading. 9th European Elastin Meeting (EEM), Stuttgart, Germany, 17-19 June 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.actbio.2016.10.011