Dr Isaac Afara

Research Fellow - Biomedical Engine

School of Information Technology and Electrical Engineering
Faculty of Engineering, Architecture and Information Technology
i.afara@uq.edu.au
+61 7 336 54307

Overview

Dr Afara completed Bachelor's degree in Electrical Engineering from the University of Lagos, Nigeria in 2006, and Ph.D. degree in Medical Engineering from Queensland University of Technology in 2012. His early research (including his doctoral thesis) focused on developing near-infrared (NIR) spectroscopy and related biophotonics methodologies for rapid characterization and diagnostic assessment of biological tissues, with particular focus on connective tissues. His research in applied biospectroscopy has contributed to development of optical methods for quantitative diagnosis of connective tissue pathologies, such osteoarthritis and related musculoskeletal conditions. Dr Afara's research has so far led to the development of a novel photonics-based tool for real-time diagnostic assessment of connective tissue integrity during arthroscopic surgery.

Currently, his focus has expanded to more basic and fundamental biophotonics research, with specific interest in understanding light-tissue interaction using computational approaches. His long-term research goal is to develop next-generation medical devices with real-time sensing and diagnostic capabilities by combining basic, applied and computational biophotonics.

Qualifications

  • Doctor of Philosophy, Queensland University of Technology

Publications

  • Rehman, Hafeez Ur, Tafintseva, Valeria, Zimmermann, Boris, Solheim, Johanne Heitmann, Virtanen, Vesa, Shaikh, Rubina, Nippolainen, Ervin, Afara, Isaac, Saarakkala, Simo, Rieppo, Lassi, Krebs, Patrick, Fomina, Polina, Mizaikoff, Boris and Kohler, Achim (2022). Preclassification of broadband and sparse infrared data by multiplicative signal correction approach. Molecules, 27 (7) 2298. doi: 10.3390/molecules27072298

  • Torniainen, Jari, Ristaniemi, Aapo, Sarin, Jaakko K., Prakash, Mithilesh, Afara, Isaac O., Finnilä, Mikko A.J., Stenroth, Lauri, Korhonen, Rami K. and Töyräs, Juha (2022). Near infrared spectroscopic evaluation of biochemical and crimp properties of knee joint ligaments and patellar tendon. PLoS ONE, 17 (2) e0263280. doi: 10.1371/journal.pone.0263280

  • Tafintseva, Valeria, Lintvedt, Tiril Aurora, Solheim, Johanne Heitmann, Zimmermann, Boris, Rehman, Hafeez Ur, Virtanen, Vesa, Shaikh, Rubina, Nippolainen, Ervin, Afara, Isaac, Saarakkala, Simo, Rieppo, Lassi, Krebs, Patrick, Fomina, Polina, Mizaikoff, Boris and Kohler, Achim (2022). Preprocessing strategies for sparse infrared spectroscopy: a case study on cartilage diagnostics. Molecules, 27 (3) 873. doi: 10.3390/molecules27030873

View all Publications

Supervision

  • Master Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

Conference Publication

  • Nikkonen, S., Afara, I., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Artificial neural network analysis of blood oxygen saturation signal enables accurate automatic screening of sleep apnea. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.624

  • Korkalainen, H., Aakko, J., Nikkonen, S., Kainulainen, S., Leino, A., Duce, B., Afara, I. O., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Deep learning enables accurate sleep staging based on a single frontal EEG channel. 15th World Sleep Congress, World Sleep 2019, Vancouver, Canada, 20-25 September, 2019 . Amsterdam, Netherlands: Elsevier BV.

  • Kainulainen, S., Toyras, J., Oksenberg, A., Korkalainen, H., Afara, I., Leino, A., Kalevo, L., Nikkonen, S., Gadoth, N., Kulkas, A., Myllymaa, S. and Leppanen, T. (2019). Differentiating Sleepy and non-sleepy obstructive sleep apnea patients using nocturnal pulse oximetry and deep learning. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.508

  • Ala-Myllymäki, Juho, Paakkonen, Tommi, Töyräsa, Juha and Afara, Isaac O. (2019). Arthroscopic near-infrared spectroscopic prediction of human meniscus properties. Bio-Optics: Design and Application 2019, Tucson, AZ, United States, 14–17 April 2019. Washington, D.C.: Optical Society of America (OSA). doi: 10.1364/BODA.2019.JT4A.35

  • Virtanen, V. K., Nippolainen, E., Shaikh, R., Afara, I., Toyras, J., Saarakkala, S. and Rieppo, L. (2019). Detection of enzymatically and mechanically induced degradation of bovine articular cartilage tissue with mid-infrared spectroscopy. OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis, Toronto, Canada, 2-5 May 2019. Oxford, United Kingdom: Elsevier . doi: 10.1016/j.joca.2019.02.035

  • Bibikova, Olga, Nippolainen, Ervin, Afara, Isaac, Haas, Julian, Virtanen, Vesa, Rieppo, Lasi, Adomaviciute, Sonata, Brommer, Harold, van Weeren, René, Melenteva, Anastasija, Belikova, Valeria, Zabarylo, Urszula, Minet, Olaf, Töyräs, Juha, Sablinskas, Valdas, Mizaikoff, Boris and Artyushenko, Viacheslav (2019). Multi-spectral fiber spectroscopy methods as solutions for label-free medical diagnostics. SPIE BiOS, 2019, San Francisco, CA, United States, 4 March 2019. Bellingham, WA, United States: SPIE. doi: 10.1117/12.2509174

  • Torniainen, Jari, Afara, Isaac O., Prakash, Mithilesh, Sarin, Jaakko K., Stenroth, Lauri and Töyräs, Juha (2019). Automated preprocessing of near infrared spectroscopic data. Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), Tucson, AZ, United States, 14-17 April 2019. Washington, DC, United States: Optical Society of America. doi: 10.1364/BODA.2019.DS2A.6

  • Nippolainen, Ervin, Shaikh, Rubina, Virtanen, Vesa, Rieppo, Lassi, Afara, Isaac, Saarakkala, Simo and Töyräs, Juha (2019). Mid-infrared and near infrared spectroscopic analysis of mechanically and enzymatically damaged cartilage. Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), Tucson, AZ USA, 14-17 April 2019. Washington, DC USA: Optical Society of America. doi: 10.1364/BODA.2019.JT4A.37

  • Shaikh, Rubina, Nippolainen, Ervin, Virtanen, Vesa, Rieppo, Lassi, Haas, Julian, Mizaikoff, Boris, Artyushenko, Viacheslav, Bibikova, Olga, Afara, Isaac, Saarakkala, Simo and Töyräs, Juha (2019). Mid-infrared spectroscopic assessment of cartilage degeneration. Biophotonics Congress, Tucson, AZ, United States, 14–17 April 2019. Washington, D.C.: Optical Society of America (OSA). doi: 10.1364/BODA.2019.DS1A.3

  • Afara, Isaac O., Sarin, Jaakko K., Ojanen, Simo, Finnila, Mikko, Herzog, Walter, Saarakkala, Simo, Korhonen, Rami K. and To¨yräs, Juha (2018). Deep learning classification of cartilage integrity using near infrared spectroscopy. Clinical and Translational Biophotonics, TRANSLATIONAL 2018, Hollywood, FL United States, 3-6 April 2018. Washington, DC United States: The Optical Society. doi: 10.1364/TRANSLATIONAL.2018.JTu3A.27

  • Prakash, Mithilesh, Joukainen, Antti, Sarin, Jaakko, Rieppo, Lassi, Afara, Isaac and Töyräs, Juha (2018). Near-infrared spectroscopy based arthroscopic evaluation of human knee joint cartilage, through automated selection of an anatomically specific regression model. Optical Tomography and Spectroscopy (OTS 2018), Hollywood, FL, United States, 3-6 April 2018. Washington, D.C.: OSA - The Optical Society. doi: 10.1364/OTS.2018.OF4D.3

  • Ala-Myllymäki, Juho, To¨yräs, Juha and Afara, Isaac O. (2018). Near-infrared spectroscopy: A potential tool for mapping meniscus properties. Clinical and Translational Biophotonics, TRANSLATIONAL 2018, Hollywood, FL United States, 3-6 April 2018. Washington, DC United States: The Optical Society. doi: 10.1364/TRANSLATIONAL.2018.JW3A.38

  • Sarin, Jaakko K., te Moller, Nikae, Brommer, Harold, van Weeren, Rene´, Mancini, Irina, Malda, Jos, Afara, Isaac O. and Töyräs, Juha (2018). Spectroscopic evaluation of post-traumatic osteoarthritis in Shetland ponies. Optical Tomography and Spectroscopy (OTS 2018), Hollywood, FL, United States, 3-6 April 2018. Washington, D.C.: OSA - The Optical Society. doi: 10.1364/OTS.2018.OTu4D.5

  • Pawlak, Z., Urbaniak, W., Yusuf, K. Q., Afara, I. O. and Oloyede, A. (2013). Lamellar-roller-bearing lubrication model on the cartilage surface. Politecnico di Torino (DIMEAS).

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor