Dr Sonia Shah

NHMRC Early Career Fellow

Institute for Molecular Bioscience

Overview

Sonia was awarded her PhD at University College London in Jan 2014 on the discovery and application of genetic determinants of cardiovascular disease risk factors, with particular application in disease risk prediction and determining causality using Mendelian randomisation. Her interests lie in using genetic, epigenetic and genomic data to better understand the underlying architecture of complex disease traits. In 2018, she was awarded an NHMRC Early Career Researcher fellowship to investigate the relationship between cardiovascular and neurodegenerative disease using large-scale genetic and omic data.

A full list of publications can be found at https://orcid.org/0000-0001-5860-4526

Qualifications

  • Doctor of Philosophy, University College London
  • Master of Science, The University of Manchester

Publications

  • Chauquet, Solal, Zhu, Zhihong, O'Donovan, Michael C., Walters, James T. R., Wray, Naomi R. and Shah, Sonia (2021). Association of antihypertensive drug target genes with psychiatric disorders: a Mendelian randomization study. JAMA Psychiatry. doi: 10.1001/jamapsychiatry.2021.0005

  • Legault, Marc-André, Sandoval, Johanna, Provost, Sylvie, Barhdadi, Amina, Lemieux Perreault, Louis-Philippe, Shah, Sonia, Lumbers, R. Thomas, de Denus, Simon, Tyl, Benoit, Tardif, Jean-Claude and Dubé, Marie-Pierre (2020). A genetic model of ivabradine recapitulates results from randomized clinical trials. PLOS ONE, 15 (7) e0236193, e0236193. doi: 10.1371/journal.pone.0236193

  • Shah, Sonia, Henry, Albert, Roselli, Carolina, Lin, Honghuang, Sveinbjörnsson, Garðar, Fatemifar, Ghazaleh, Hedman, Åsa K., Wilk, Jemma B., Morley, Michael P., Chaffin, Mark D., Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Aragam, Krishna G., Ärnlöv, Johan, Backman, Joshua D., Biggs, Mary L., Bloom, Heather L., Brandimarto, Jeffrey, Brown, Michael R., Buckbinder, Leonard, Carey, David J., Chasman, Daniel I., Chen, Xing, Chen, Xu, Chung, Jonathan, Chutkow, William ... Lumbers, R. Thomas (2020). Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11 (1) 163, 163. doi: 10.1038/s41467-019-13690-5

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Supervision

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

  • Chauquet, Solal, Zhu, Zhihong, O'Donovan, Michael C., Walters, James T. R., Wray, Naomi R. and Shah, Sonia (2021). Association of antihypertensive drug target genes with psychiatric disorders: a Mendelian randomization study. JAMA Psychiatry. doi: 10.1001/jamapsychiatry.2021.0005

  • Legault, Marc-André, Sandoval, Johanna, Provost, Sylvie, Barhdadi, Amina, Lemieux Perreault, Louis-Philippe, Shah, Sonia, Lumbers, R. Thomas, de Denus, Simon, Tyl, Benoit, Tardif, Jean-Claude and Dubé, Marie-Pierre (2020). A genetic model of ivabradine recapitulates results from randomized clinical trials. PLOS ONE, 15 (7) e0236193, e0236193. doi: 10.1371/journal.pone.0236193

  • Shah, Sonia, Henry, Albert, Roselli, Carolina, Lin, Honghuang, Sveinbjörnsson, Garðar, Fatemifar, Ghazaleh, Hedman, Åsa K., Wilk, Jemma B., Morley, Michael P., Chaffin, Mark D., Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Aragam, Krishna G., Ärnlöv, Johan, Backman, Joshua D., Biggs, Mary L., Bloom, Heather L., Brandimarto, Jeffrey, Brown, Michael R., Buckbinder, Leonard, Carey, David J., Chasman, Daniel I., Chen, Xing, Chen, Xu, Chung, Jonathan, Chutkow, William ... Lumbers, R. Thomas (2020). Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11 (1) 163, 163. doi: 10.1038/s41467-019-13690-5

  • McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w

  • Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1

  • Ballantyne, Christie M., Shah, Sukrut, Sapre, Aditi, Ashraf, Tanya B., Tobias, Sandra C., Sahin, Tayfun, Ye, Ping, Dong, Yugang, Sheu, Wayne Huey-Heng, Kang, Duk-Hyun, Ferreira Rossi, Paulo Roberto, Moiseeva, Yulia, Briones, Ignacio Rodriguez, Johnson-Levonas, Amy O. and Mitchel, Yale B. (2017). A multiregional, randomized evaluation of the lipid-modifying efficacy and tolerability of anacetrapib added to ongoing statin therapy in patients with hypercholesterolemia or low high-density lipoprotein cholesterol. American Journal of Cardiology, 120 (4), 569-576. doi: 10.1016/j.amjcard.2017.03.255

  • Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302

  • Del Valle, Ignacio, Buonocore, Federica, Duncan, Andrew J., Lin, Lin, Barenco, Martino, Parnaik, Rahul, Shah, Sonia, Hubank, Mike, Gerrelli, Dianne and Achermann, John C. (2017). A genomic atlas of human adrenal and gonad development. Wellcome Open Research, 2 25, 1-42. doi: 10.12688/wellcomeopenres.11253.2

  • Hedman, Åsa K., Mendelson, Michael M., Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui, Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao, McRae, Allan F., Demissie, Serkalem, Shah, Sonia, Starr, John M., Cupples, L. Adrienne, Deloukas, Panos, Spector, Timothy D., Sundstrom, Johan, Krauss, Ronald M., Arnett, Donna K., Deary, Ian J., Lind, Lars, Levy, Daniel and Ingelsson, Erik (2017). Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics, 10 (1) 001487. doi: 10.1161/CIRCGENETICS.116.001487

  • Ballantyne, Christie M., Shah, Sukrut, Kher, Uma, Hunter, John A., Gill, Geraldine G., Cressman, Michael D., Ashraf, Tanya B., Johnson-Levonas, Amy O. and Mitchel, Yale B. (2017). Lipid-modifying efficacy and tolerability of anacetrapib added to ongoing statin therapy in patients with hypercholesterolemia or low high-density lipoprotein cholesterol. American Journal of Cardiology, 119 (3), 388-396. doi: 10.1016/j.amjcard.2016.10.032

  • Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215

  • Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona ... Dehghan, Abbas (2016). DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology, 17 (1) 255, 255-255. doi: 10.1186/s13059-016-1119-5

  • Joehanes, Roby, Just, Allan C., Marioni, Riccardo E., Pilling, Luke C., Reynolds, Lindsay M., Mandaviya, Pooja R., Guan, Weihua, Xu, Tao, Elks, Cathy E., Aslibekyan, Stella, Moreno-Macias, Hortensia, Smith, Jennifer A., Brody, Jennifer A., Dhingra, Radhika, Yousefi, Paul, Pankow, James S., Kunze, Sonja, Shah, Sonia H., McRae, Allan F., Lohman, Kurt, Sha, Jin, Absher, Devin M., Ferrucci, Luigi, Zhao, Wei, Demerath, Ellen W., Bressler, Jan, Grove, Megan L., Huan, Tianxiao, Liu, Chunyu ... London, Stephanie J. (2016). Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics, 9 (5), 436-447. doi: 10.1161/CIRCGENETICS.116.001506

  • Ehret, G.B., Ferreira, T., Chasman, D.I., Jackson, A.U., Schmidt, E.M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L.A., Kanoni, S., Petersen, A.-K., Pihur, V., Strawbridge, R.J., Shungin, D., Hughes, M.F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S., Kleber, M.E., Guo, X., Lyytikainen, L.-P., Fava, C., Eriksson, N., Nolte, I.M., Magnusson, P.K., Salfati, E.L., Rallidis, L.S. ... Munroe, P.B. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics, 48 (10), 1171-1184. doi: 10.1038/ng.3667

  • McLachlan, Stela, Giambartolomei, Claudia, White, Jon, Charoen, Pimphen, Wong, Andrew, Finan, Chris, Engmann, Jorgen, Shah, Tina, Hersch, Micha, Podmore, Clara, Cavadino, Alana, Jefferis, Barbara J., Dale, Caroline E., Hypponen, Elina, Morris, Richard W., Casas, Juan P., Kumari, Meena, Ben-Shlomo, Yoav, Gaunt, Tom R., Drenos, Fotios, Langenberg, Claudia, Kuh, Diana, Kivimaki, Mika, Rueedi, Rico, Waeber, Gerard, Hingorani, Aroon D., Price, Jacqueline F., Walker, Ann P., Cooper, Jackie ... Zabaneh, Delilah (2016). Replication and characterization of association between ABO SNPs and red blood cell traits by meta-analysis in Europeans. PLoS ONE, 11 (6) e0156914, e0156914. doi: 10.1371/journal.pone.0156914

  • Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041. International Journal of Epidemiology, 47 (1) dyx217, 356-356. doi: 10.1093/ije/dyx233

  • Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). The epigenetic clock and telomere length are independently associated with chronological age and mortality. International Journal of Epidemiology, 45 (2), 424-432. doi: 10.1093/ije/dyw041

  • White, Jon, Sofat, Reecho, Hemani, Gibran, Shah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, Kruger, Felix A., Giambartolomei, Claudio, Swerdlow, Daniel I., Palmer, Tom, McLachlan, Stela, Langenberg, Claudia, Zabaneh, Delilah, Lovering, Ruth, Cavadino, Alana, Jefferis, Barbara, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom R., Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Ebrahim, Shah, Lawlor, Debbie A., Talmud, Philippa J. ... Hingorani, Aroon D. (2016). Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis. The Lancet Diabetes and Endocrinology, 4 (4), 327-336. doi: 10.1016/S2213-8587(15)00386-1

  • Chen, Brian H., Marioni, Riccardo E., Colicino, Elena, Peters, Marjolein J., Ward-Caviness, Cavin K., Tsai, Pei-Chien, Roetker, Nicholas S., Just, Allan C., Demerath, Ellen W., Guan, Weihua, Bressler, Jan, Fornage, Myriam, Studenski, Stephanie, Vandiver, Amy R., Moore, Ann Zenobia, Tanaka, Toshiko, Kiel, Douglas P., Liang, Liming, Vokonas, Pantel, Schwartz, Joel, Lunetta, Kathryn L., Murabito, Joanne M., Bandinelli, Stefania, Hernandez, Dena G., Melzer, David, Nalls, Michael, Pilling, Luke C., Price, Timothy R., Singleton, Andrew B. ... Horvath, Steve (2016). DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging, 8 (9), 1844-1865. doi: 10.18632/aging.101020

  • Bui, Masato, Benyamin, Beben, Shah, Sonia, Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W. and McRae, Allan F. (2015). Sharing a placenta is associated with a greater similarity in DNA methylation in monochorionic versus dichorionic twin pars in blood at age 14. Twin Research and Human Genetics, 18 (6), 680-685. doi: 10.1017/thg.2015.87

  • Persson, Jonas, Strawbridge, Rona J., McLeod, Olga, Gertow, Karl, Silveira, Angela, Baldassarre, Damiano, Van Zuydam, Natalie, Shah, Sonia, Fava, Cristiano, Gustafsson, Stefan, Veglia, Fabrizio, Sennblad, Bengt, Larsson, Malin, Sabater-Lleal, Maria, Leander, Karin, Gigante, Bruna, Tabak, Adam, Kivimaki, Mika, Kauhanen, Jussi, Rauramaa, Rainer, Smit, Andries J., Mannarino, Elmo, Giral, Philippe, Humphries, Steve E., Tremoli, Elena, de Faire, Ulf, Lind, Lars, Ingelsson, Erik, Hedblad, Bo ... Soderberg, Stefan (2015). Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease. Journal of the American Heart Association, 4 (8), 1-13. doi: 10.1161/JAHA.115.001853

  • Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Ritchie, Stuart J., Muniz-Terrera, Graciela, Harris, Sarah E., Gibson, Jude, Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Taylor, Adele, Murphy, Lee, Starr, John M., Horvath, Steve, Visscher, Peter M., Wray, Naomi R. and Deary, Ian J. (2015). The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology, 44 (4), 1388-1396. doi: 10.1093/ije/dyu277

  • Shah, Sonia, Bonder, Marc J., Marioni, Riccardo E., Zhu, Zhihong, McRae, Allan F., Zhernakova, Alexandra, Harris, Sarah E., Liewald, Dave, Henders, Anjali K., Mendelson, Michael M., Liu, Chunyu, Joehanes, Roby, Liang, Liming, Levy, Daniel, Martin, Nicholas G., Starr, John M., Wijmenga, Cisca, Wray, Naomi R., Yang, Jian, Montgomery, Grant W., Franke, Luke, Deary, Ian J., Visscher, Peter M. and BIOS Consortium (2015). Improving phenotypic prediction by combining genetic and epigenetic associations. American Journal of Human Genetics, 97 (1), 75-85. doi: 10.1016/j.ajhg.2015.05.014

  • He, Ji, Tang, Lu, Benyamin, Beben, Shah, Sonia, Hemani, Gib, Liu, Rong, Ye, Shan, Liu, Xiaolu, Ma, Yan, Zhang, Huagang, Cremin, Katie, Leo, Paul, Wray, Naomi R., Visscher, Peter M., Xu, Huji, Brown, Matthew A., Bartlett, Perry F., Mangelsdorf, Marie and Fan, Dongsheng (2015). C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis. Neurobiology of Aging, 36 (9), 2660.e1-2660.e8. doi: 10.1016/j.neurobiolaging.2015.06.002

  • Holmes, Michael V., Asselbergs, Folkert W., Palmer, Tom M., Drenos, Fotios, Lanktree, Matthew B., Nelson, Christopher P., Dale, Caroline E., Padmanabhan, Sandosh, Finan, Chris, Swerdlow, Daniel I., Tragante, Vinicius, van Iperen, Erik P. A., Sivapalaratnam, Suthesh, Shah, Sonia, Elbers, Clara C., Shah, Tina, Engmann, Jorgen, Giambartolomei, Claudia, White, Jon, Zabaneh, Delilah, Sofat, Reecha, McLachlan, Stela, Doevendans, Pieter A., Balmforth, Anthony J., Hall, Alistair S., North, Kari E., Almoguera, Berta, Hoogeveen, Ron C., Cushman, Mary ... Casas, Juan P. (2015). Mendelian randomization of blood lipids for coronary heart disease. European Heart Journal, 36 (9), 539-550. doi: 10.1093/eurheartj/eht571

  • Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Chen, Brian H., Colicino, Elena, Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Feinberg, Andrew P., Fallin, M. Daniele, Multhaup, Michael L., Jaffe, Andrew E., Joehanes, Roby, Schwartz, Joel, Just, Allan C., Lunetta, Kathryn L., Murabito, Joanne M., Starr, John M., Horvath, Steve, Baccarelli, Andrea A., Levy, Daniel, Visscher, Peter M. ... Deary, Ian J. (2015). DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology, 16 (1) 25, 25.1-25.12. doi: 10.1186/s13059-015-0584-6

  • Brinton, Eliot A., Kher, Uma, Shah, Sukrut, Cannon, Christopher P., Davidson, Michael, Gotto, Antonio M., Ashraf, Tanya B., Sisk, Christine McCrary, Dansky, Hayes, Mitchel, Yale, Barter, Philip and DEFINE Investigators (2015). Effects of anacetrapib on plasma lipids in specific patient subgroups in the DEFINE (Determining the efficacy and tolerability of CETP INhibition with AnacEtrapib) trial. Journal of Clinical Lipidology, 9 (1), 65-71. doi: 10.1016/j.jacl.2014.10.005

  • Herder, Christian, Nuotio, Marja-Liisa, Shah, Sonia, Blankenberg, Stefan, Brunner, Eric J., Carstensen, Maren, Gieger, Christian, Grallert, Harald, Jula, Antti, Kahonen, Mika, Kettunen, Johannes, Kivimaki, Mika, Koenig, Wolfgang, Kristiansson, Kati, Langenberg, Claudia, Lehtimaki, Terho, Luotola, Kari, Marzi, Carola, Mueller, Christian, Peters, Annette, Prokisch, Holger, Raitakari, Olli, Rathmann, Wolfgang, Roden, Michael, Salmi, Marko, Schramm, Katharina, Swerdlow, Daniel, Tabak, Adam G., Thorand, Barbara ... Salomaa, Veikko (2014). Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes, 63 (12), 4343-4359. doi: 10.2337/db14-0731

  • Futema, Marta, Shah, Sonia, Cooper, Jackie A., Li, KahWa, Whittall, Ros A., Sharifi, Mahtab, Goldberg, Olivia, Drogari, Euridiki, Mollaki, Vasilik, Wiegman, Albert, Defesche, Joep, D'Agostino, Maria N., D'Angelo, Antonietta, Rubba, Paolo, Fortunato, Giuliana, Walus-Miarka, Malgorzata, Hegele, Robert A., Aderayo Bamimore, Mary, Durst, Ronen, Leitersdorf, Eran, Mulder, Monique T., Roeters van Lennep, Jeanine E., Sijbrands, Eric J., Whittaker, John C., Talmud, Philippa J. and Humphries, Steve E. (2014). Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries. Clinical Chemistry, 61 (1), 231-238. doi: 10.1373/clinchem.2014.231365

  • Shah, Sonia, McRae, Allan F., Marioni, Riccardo E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Starr, John M., Wray, Naomi R., Deary, Ian J. and Visscher, Peter M. (2014). Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research, 24 (11), 1725-1733. doi: 10.1101/gr.176933.114

  • Gigante, Bruna, Leander, Karin, Vikström, Max, Baldassarre, Damiano, Veglia, Fabrizio, Strawbridge, Rona J., McLeod, Olga, Gertow, Karl, Sennblad, Bengt, Shah, Sonia, Zabaneh, Delilah, Humphries, Steve E., Kauhanen, Jussi, Rauramaa, Rainer, Smit, Andries J., Mannarino, Elmo, Giral, Philippe, Tremoli, Elena, Hamsten, Anders, Frostegård, Johan and de Faire, Ulf (2014). Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men. Atherosclerosis, 236 (2), 394-399. doi: 10.1016/j.atherosclerosis.2014.07.030

  • Holmes, Michael V., Dale, Caroline E., Zuccolo, Luisa, Silverwood, Richard J., Guo, Yiran, Ye, Zheng, Prieto-Merino, David, Dehghan, Abbas, Trompet, Stella, Wong, Andrew, Cavadino, Alana, Drogan, Dagmar, Padmanabhan, Sandosh, Li, Shanshan, Yesupriya, Ajay, Leusink, Maarten, Sundstrom, Johan, Hubacek, Jaroslav A., Pikhart, Hynek, Swerdlow, Daniel I., Panayiotou, Andrie G., Borinskaya, Svetlana A., Finan, Chris, Shah, Sonia, Kuchenbaecker, Karoline B., Shah, Tina, Engmann, Jorgen, Folkersen, Lasse, Eriksson, Per ... Casas, Juan P. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ - British Medical Journal, 349 (jul10 6) g4164, g4164-g4164. doi: 10.1136/bmj.g4164

  • McRae, Allan F., Powell, Joseph E., Henders, Anjali K., Bowdler, Lisa, Hemani, Gibran, Shah, Sonia, Painter, Jodie N., Martin, Nicholas G., Visscher, Peter M. and Montgomery, Grant W. (2014). Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biology, 15 (5), 1-10. doi: 10.1186/gb-2014-15-5-r73

  • Gotto, Antonio M., Kher, Uma, Chatterjee, Manash Shankar, Liu, Yang, Li, Xiujiang Susie, Vaidya, Sanskruti, Cannon, Christopher P., Brinton, Eliot A., Moon, Jennifer E., Shah, Sukrut, Dansky, Hayes M., Mitchel, Yale and Barter, Philip (2014). Lipids, safety parameters, and drug concentrations after an additional 2 years of treatment with Anacetrapib in the DEFINE study. Journal of Cardiovascular Pharmacology and Therapeutics, 19 (6), 543-549. doi: 10.1177/1074248414529621

  • Tragante, Vinicius, Barnes, Michael R., Ganesh, Santhi K., Lanktree, Matthew B., Guo, Wei, Franceschini, Nora, Smith, Erin N., Johnson, Toby, Holmes, Michael V., Padmanabhan, Sandosh, Karczewski, Konrad J., Almoguera, Berta, Barnard, John, Baumert, Jens, Chang, Yen-Pei Christy, Elbers, Clara C., Farrall, Martin, Fischer, Mary E., Gaunt, Tom R., Gho, Johannes M. I. H., Gieger, Christian, Goel, Anuj, Gong, Yan, Isaacs, Aaron, Kleber, Marcus E., Leach, Irene Mateo, McDonough, Caitrin W., Meijs, Matthijs F. L., Melander, Olle ... Keating, Brendan J. (2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94 (3), 349-360. doi: 10.1016/j.ajhg.2013.12.016

  • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium and Shah, Sonia (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics, 46 (3), 234-246. doi: 10.1038/ng.2897

  • Gotto Jr., Antonio M., Cannon, Christopher P., Li, Xiujiang Susie, Vaidya, Sanskruti, Kher, Uma, Brinton, Eliot A., Davidson, Michael, Moon, Jennifer E., Shah, Sukrut, Dansky, Hayes M., Mitchel, Yale and Barter, Philip (2014). Evaluation of lipids, drug concentration, and safety parameters following cessation of treatment with the cholesteryl ester transfer protein inhibitor anacetrapib in patients with or at high risk for coronary heart disease. American Journal of Cardiology, 113 (1), 76-83. doi: 10.1016/j.amjcard.2013.08.041

  • Do, Ron, Willer, Cristen J., Schmidt, Ellen M., Sengupta, Sebanti, Gao, Chi, Peloso, Gina M., Gustafsson, Stefan, Kanoni, Stavroula, Ganna, Andrea, Chen, Jin, Buchkovich, Martin L., Mora, Samia, Beckmann, Jacques S., Bragg-Gresham, Jennifer L., Chang, Hsing-Yi, Demirkan, Ayse, Den Hertog, Heleen M., Donnelly, Louise A., Ehret, Georg B., Esko, Tonu, Feitosa, Mary F., Ferreira, Teresa, Fischer, Krista, Fontanillas, Pierre, Fraser, Ross M., Freitag, Daniel F., Gurdasani, Deepti, Heikkila, Kauko, Hyppoenen, Elina ... Kathiresan, Sekar (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 45 (11), 1345-1352. doi: 10.1038/ng.2795

  • Willer C.J., Schmidt E.M., Sengupta S., Peloso G.M., Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich M.L., Mora S., Beckmann J.S., Bragg-Gresham J.L., Chang H.-Y., Demirkan A., Den Hertog H.M., Do R., Donnelly L.A., Ehret G.B., Esko T., Feitosa M.F., Ferreira T., Fischer K., Fontanillas P., Fraser R.M., Freitag D.F., Gurdasani D., Heikkila K., Hypponen E., Isaacs A. ... Abecasis G.R. (2013). Discovery and refinement of loci associated with lipid levels. Nature Genetics, 45 (11), 1274-1285. doi: 10.1038/ng.2797

  • Gaunt T.R., Zabaneh D., Shah S., Guyatt A., Ladroue C., Kumari M., Drenos F., Shah T., Talmud P.J., Casas J.P., Lowe G., Rumley A., Lawlor D.A., Kivimaki M., Whittaker J., Hingorani A.D., Humphries S.E. and Day I.N. (2013). Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip. Thrombosis and Haemostasis, 110 (5), 995-1003. doi: 10.1160/TH13-02-0087

  • Shah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, White, Jon, Giambartolomei, Claudia, McLachlan, Stela, Zabaneh, Delilah, Cavadino, Alana, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom, Holmes, Michael V., Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Sofat, Reecha, Caulfield, Mark, Ebrahim, Shah, Lawlor, Debbie A., Talmud, Philippa J., Humphries, Steve E., Power, Christine, Hypponen, Elina, Richards, Marcus, Hardy, Rebecca ... Hingorani, Aroon D. (2013). Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS ONE, 8 (8) e71345, e71345. doi: 10.1371/journal.pone.0071345

  • Ganesh, Santhi K., Tragante, Vinicius, Guo, Wei, Guo, Yiran, Lanktree, Matthew B., Smith, Erin N., Johnson, Toby, Castillo, Berta Almoguera, Barnard, John, Baumert, Jens, Chang, Yen-Pei Christy, Elbers, Clara C., Farrall, Martin, Fischer, Mary E., Gaunt, Nora Franceschini, H. Gho, Johannes M.I., Gieger, Christian, Gong, Yan, Isaacs, Aaron, Kleber, Marcus E., Leach, Irene Mateo, McDonough, Caitrin W., Meijs, Matthijs F.L., Mellander, Olle, Molony, Cliona M., Nolte, Ilja M., Price, Sandosh Padmanabhan, Rajagopalan, Ramakrishnan, Shaffer, Jonathan ... Asselbergs, Folkert W. (2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics, 22 (16) ddt177, 3394-3395. doi: 10.1093/hmg/ddt177

  • Shah T., Zabaneh D., Gaunt T., Swerdlow D.I., Shah S., Talmud P.J., Day I.N., Whittaker J., Holmes M.V., Sofat R., Humphries S.E., Kivimaki M., Kumari M., Hingorani A.D. and Casas J.P. (2013). Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. Circulation: Cardiovascular Genetics, 6 (2), 163-170. doi: 10.1161/CIRCGENETICS.112.964254

  • Shah S., Casas J.P., Gaunt T.R., Cooper J., Drenos F., Zabaneh D., Swerdlow D.I., Shah T., Sofat R., Palmen J., Kumari M., Kivimaki M., Ebrahim S., Smith G.D., Lawlor D.A., Talmud P.J., Whittaker J., Day I.N.M., Hingorani A.D. and Humphries S.E. (2013). Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. European Heart Journal, 34 (13), 972-981. doi: 10.1093/eurheartj/ehs243

  • Ganesh, S.K., Tragante, V., Guo, W., Guo, Y., Lanktree, M.B., Smith, E.N., Johnson, T., Castillo, B.A., Barnard, J., Baumert, J., Chang, Y.-P.C., Elbers, C.C., Farrall, M., Fischer, M.E., Franceschini, N., Gaunt, T.R., Gho, J.M.I.H., Gieger, C., Gong, Y., Isaacs, A., Kleber, M.E., Leach, I.M., McDonough, C.W., Meijs, M.F., Mellander, O., Molony, C.M., Nolte, I.M., Padmanabhan, S., Price, T.S. ... Asselbergs, F.W. (2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics, 22 (8), 1663-1678. doi: 10.1093/hmg/dds555

  • Talmud, Philippa J., Shah, Sonia, Whittall, Ros, Futema, Marta, Howard, Philip, Cooper, Jackie A., Harrison, Seamus C., Li, KaWah, Drenos, Fotios, Karpe, Frederik, Neil, H. Andrew W., Descamps, Olivier S., Langenberg, Claudia, Lench, Nicholas, Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D., Kumari, Meena and Humphries, Steve E. (2013). Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet, 381 (9874), 1293-1301. doi: 10.1016/S0140-6736(12)62127-8

  • Harrison S.C., Zabaneh D., Asselbergs F.W., Drenos F., Jones G.T., Shah S., Gertow K., Sennblad B., Strawbridge R.J., Gigante B., Holewijn S., De Graaf J., Vermeulen S., Folkersen L., van Rij A.M., Baldassarre D., Veglia F., Talmud P.J., Deanfield J.E., Agu O., Kivimaki M., Kumari M., Bown M.J., Nyyssonen K., Rauramaa R., Smit A.J., Franco-Cereceda A., Giral P., Mannarino E. ... Humphries S.E. (2013). A gene-centric study of common carotid artery remodelling. Atherosclerosis, 226 (2), 440-446. doi: 10.1016/j.atherosclerosis.2012.11.002

  • Shah S., Casas J.-P., Drenos F., Whittaker J., Deanfield J., Swerdlow D.I., Holmes M.V., Kivimaki M., Langenberg C., Wareham N., Gertow K., Sennblad B., Strawbridge R.J., Baldassarre D., Veglia F., Tremoli E., Gigante B., De Faire U., Kumari M., Talmud P.J., Hamsten A., Humphries S.E. and Hingorani A.D. (2013). Causal relevance of blood lipid fractions in the development of carotid atherosclerosis mendelian randomization analysis. Circulation: Cardiovascular Genetics, 6 (1), 63-72. doi: 10.1161/CIRCGENETICS.112.963140

  • Gaunt, Tom R, Shah, Sonia, Nelson, Christopher P, Drenos, Fotios, Braund, Peter S., Adeniran, Ismail, Folkersen, Lasse, Lawlor, Debbie A., Casas, Juan-Pablo, Amuzu, Antoinette, Kivimaki, Mika, Whittaker, John, Eriksson, Per, Zhang, Henggui, Hancox, Jules C., Tomaszewski, Maciej, Burton, Paul R., Tobin, Martin D., Humphries, Steve E., Talmud, Philippa J., Macfarlane, Peter W., Hingorani, Aroon D., Samani, Nilesh J., Kumari, Meena and Day, Ian N.M. (2012). Integration of genetics into a systems model of electrocardiographic traits using humancvd beadchip. Circulation: Cardiovascular Genetics, 5 (6), 630-638. doi: 10.1161/CIRCGENETICS.112.962852

  • Lanktree, Matthew B., Guo, Yiran, Murtaza, Muhammed, Glessner, Joseph T., Bailey, Swneke D., Onland-Moret, N. Charlotte, Lettre, Guillaume, Ongen, Halit, Rajagopalan, Ramakrishnan, Johnson, Toby, Shen, Haiqing, Nelson, Christopher P., Klopp, Norman, Baumert, Jens, Padmanabhan, Sandosh, Pankratz, Nathan, Pankow, James S., Shah, Sonia, Taylor, Kira, Barnard, John, Peters, Bas J., Maloney, Cliona M., Lobmeyer, Maximilian T., Stanton, Alice, Zafarmand, M. Hadi, Romaine, Simon P.R., Mehta, Amar, Van Iperen, Erik P.A., Gong, Yan ... Keating, Brendan J. (2012). Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)). American Journal of Human Genetics, 90 (6), 1116-1117. doi: 10.1016/j.ajhg.2012.05.017

  • Saxena, Richa, Elbers, Clara C., Guo, Yiran, Peter, Inga, Gaunt, Tom R., Mega, Jessica L., Lanktree, Matthew B., Tare, Archana, Castillo, Berta Almoguera, Li, Yun R., Johnson, Toby, Bruinenberg, Marcel, Gilbert-Diamond, Diane, Rajagopalan, Ramakrishnan, Voight, Benjamin F., Balasubramanyam, Ashok, Barnard, John, Bauer, Florianne, Baumert, Jens, Bhangale, Tushar, Boehm, Bernhard O., Braund, Peter S., Burton, Paul R., Chandrupatla, Hareesh R., Clarke, Robert, Cooper-DeHoff, Rhonda M., Crook, Errol D., Davey-Smith, George, Day, Ian N. ... Keating, Brendan J. (2012). Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)). American Journal of Human Genetics, 90 (4), 753-753. doi: 10.1016/j.ajhg.2012.03.001

  • Saxena, Richa, Elbers, Clara C., Guo, Yiran, Peter, Inga, Gaunt, Tom R., Mega, Jessica L., Lanktree, Matthew B., Tare, Archana, Castillo, Berta A., Li, Yun R., Johnson, Toby, Bruinenberg, Marcel, Gilbert-Diamond, Diane, Rajagopalan, Ramakrishnan, Voight, Benjamin F., Balasubramanyam, Ashok, Barnard, John, Bauer, Florianne, Baumert, Jens, Bhangale, Tushar, Bohm, Bernhard O., Braund, Peter S., Burton, Paul R., Chandrupatla, Hareesh R., Clarke, Robert, Cooper-Dehoff, Rhonda M., Crook, Errol D., Davey-Smith, George, Day, Ian N. ... Keating, Brendan J. (2012). Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics, 90 (3), 410-425. doi: 10.1016/j.ajhg.2011.12.022

  • Papp, Audrey C., Pinsonneault, Julia K., Wang, Danxin, Newman, Leslie C., Gong, Yan, Johnson, Julie A., Pepine, Carl J., Kumari, Meena, Hingorani, Aroon D., Talmud, Philippa J., Shah, Sonia, Humphries, Steve E. and Sadee, Wolfgang (2012). Cholesteryl ester transfer protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. PLoS ONE, 7 (3) e31930, e31930.1-e31930.9. doi: 10.1371/journal.pone.0031930

  • Gutstein, D. E., Krishna, R., Johns, D., Surks, H. K., Dansky, H. M., Shah, S., Mitchel, Y. B., Arena, J. and Wagner, J. A. (2012). Anacetrapib, a novel CETP inhibitor: pursuing a new approach to cardiovascular risk reduction. Clinical Pharmacology and Therapeutics, 91 (1), 109-122. doi: 10.1038/clpt.2011.271

  • Angelakopoulou, Aspasia, Shah, Tina, Sofat, Reecha, Shah, Sonia, Berry, Diane J., Cooper, Jackie, Palmen, Jutta, Tzoulaki, Ioanna, Wong, Andrew, Jefferis, Barbara J., Maniatis, Nikolas, Drenos, Fotios, Gigante, Bruna, Hardy, Rebecca, Laxton, Ross C., Leander, Karin, Motterle, Anna, Simpson, Iain A., Smeeth, Liam, Thomson, Andy, Verzilli, Claudio, Kuh, Diana, Ireland, Helen, Deanfield, John, Caulfield, Mark, Wallace, Chris, Samani, Nilesh, Munroe, Patricia B., Lathrop, Mark ... Hingorani, Aroon D. (2012). Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European Heart Journal, 33 (3), 393-407. doi: 10.1093/eurheartj/ehr225

  • Yiannakouris, N., Cooper, J. A., Shah, S., Drenos, F., Ireland, H. A., Stephens, J. W., Li, K.-W., Elkeles, R., Godsland, I. F., Kivimaki, M., Hingorani, A. D., Kumari, M., Talmud, P. J. and Humphries, S. E. (2012). IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Nutrition, Metabolism and Cardiovascular Diseases, 22 (12), 1024-1030. doi: 10.1016/j.numecd.2011.05.009

  • Gertow, Karl, Sennblad, Bengt, Strawbridge, Rona J., Ohrvik, John, Zabaneh, Delilah, Shah, Sonia, Veglia, Fabrizio, Fava, Cristiano, Kavousi, Maryam, McLachlan, Stela, Kivimaki, Mika, Bolton, Jennifer L., Folkersen, Lasse, Gigante, Bruna, Leander, Karin, Vikstrom, Max, Larsson, Malin, Silveira, Angela, Deanfield, John, Voight, Benjamin F., Fontanillas, Pierre, Sabater-Lleal, Maria, Colombo, Gualtiero I., Kumari, Meena, Langenberg, Claudia, Wareham, Nick J., Uitterlinden, André G., Gabrielsen, Anders, Hedin, Ulf ... Hamsten, Anders (2012). Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circulation: Cardiovascular Genetics, 5 (6), 656-665. doi: 10.1161/CIRCGENETICS.112.963660

  • Scott, Robert A., Lagou, Vasiliki, Welch, Ryan P., Wheeler, Eleanor, Montasser, May E., Luan, Jian’an, Mägi, Reedik, Strawbridge, Rona J., Rehnberg, Emil, Gustafsson, Stefan, Kanoni, Stavroula, Rasmussen-Torvik, Laura J., Yengo, Loïc, Lecoeur, Cecile, Shungin, Dmitry, Sanna, Serena, Sidore, Carlo, Johnson, Paul C. D., Jukema, J. Wouter, Johnson, Toby, Mahajan, Anubha, Verweij, Niek, Thorleifsson, Gudmar, Hottenga, Jouke-Jan, Shah, Sonia, Smith, Albert V., Sennblad, Bengt, Gieger, Christian, Salo, Perttu ... Barroso, Inês (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44 (9), 991-1005. doi: 10.1038/ng.2385

  • Smith, Andrew J. P., Howard, Philip, Shah, Sonia, Eriksson, Per, Stender, Stefan, Giambartolomei, Claudia, Folkersen, Lasse, Tybjaerg-Hansen, Anne, Kumari, Meena, Palmen, Jutta, Hingorani, Aroon D., Talmud, Philippa J. and Humphries, Steve E. (2012). Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays. PLoS Genetics, 8 (8) e1002908, e1002908.1-e1002908.10. doi: 10.1371/journal.pgen.1002908

  • Stables, Melanie J., Shah, Sonia, Camon, Evelyn B., Lovering, Ruth C., Newson, Justine, Bystrom, Jonas, Farrow, Stuart and Gilroy, Derek W. (2011). Transcriptomic analyses of murine resolution-phase macrophages. Blood, 118 (26), e192-e208. doi: 10.1182/blood-2011-04-345330

  • Johnson, Toby, Gaunt, Tom R., Newhouse, Stephen J., Padmanabhan, Sandosh, Tomaszewski, Marciej, Kumari, Meena, Morris, Richard W., Tzoulaki, Ioanna, O'Brien, Eoin T., Poulter, Neil R., Sever, Peter, Shields, Denis C., Thom, Simon, Wannamethee, Sasiwarang G., Whincup, Peter H., Brown, Morris J., Connell, John M., Dobson, Richard J., Howard, Philip J., Mein, Charles A., Onipinla, Abiodun, Shaw-Hawkins, Sue, Zhang, Yun, Smith, George Davey, Day, Ian N. M., Lawlor, Debbie A., Goodall, Alison H.., Fowkes, F. Gerald, Abecasis, Goncalo R. ... Munroe, Patricia B. (2011). Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics, 89 (6), 688-700. doi: 10.1016/j.ajhg.2011.10.013

  • Lanktree, Matthew B., Guo, Yiran, Murtaza, Muhammed, Glessner, Joseph T., Bailey, Swneke D., Onland-Moret, N. Charlotte, Lettre, Guillaume, Ongen, Halit, Rajagopalan, Ramakrishnan, Johnson, Toby, Shen, Haiqing, Nelson, Christopher P., Klopp, Norman, Baumert, Jens, Padmanabhan, Sandosh, Pankratz, Nathan, Pankow, James S., Shah, Sonia, Taylor, Kira, Barnard, John, Peters, Bas J., Maloney, Cliona M., Lobmeyer, Maximilian T., Stanton, Alice, Zafarmand, M. Hadi, Romaine, Simon P. R., Mehta, Amar, van Iperen, Erik P. A., Gong, Yan ... Keating, Brendan J. (2011). Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics, 88 (1), 6-18. doi: 10.1016/j.ajhg.2010.11.007

  • Ferraz-de-Souza, Bruno, Lin, Lin, Shah, Sonia, Jina, Nipurna, Hubank, Mike, Dattani, Mehul T. and Achermann, John C. (2011). ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland. FASEB Journal, 25 (4), 1166-1175. doi: 10.1096/fj.10-170522

  • Shah, Sonia, Nelson, Christopher P., Gaunt, Tom R., van der Harst, Pim, Barnes, Timothy, Braund, Peter S., Lawlor, Debbie A., Casas, Juan-Pablo, Padmanabhan, Sandosh, Drenos, Fotios, Kivimaki, Mika, Talmud, Philippa J., Humphries, Steve E., Whittaker, John, Morris, Richard W., Whincup, Peter H., Dominiczak, Anna, Munroe, Patricia B., Johnson, Toby, Goodall, Alison H., Cambien, Francois, Diemert, Patrick, Hengstenberg, Christian, Ouwehand, Willem H., Felix, Janine F., Glazer, Nicole L., Tomaszewski, Maciej, Burton, Paul R., Tobin, Martin D. ... Samani, Nilesh J. (2011). Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation: Cardiovascular Genetics, 4 (6), 626-635. doi: 10.1161/CIRCGENETICS.111.960203

  • Zabaneh, Delilah, Gaunt, Tom R., Kumari, Meena, Drenos, Fotios, Shah, Sonia, Berry, Diane, Power, Chris, Hypponen, Elina, Shah, Tina, Palmen, Jutta, Pallas, Jacky, Talmud, Philippa J., Casas, Juan Pablo, Sofat, Reecha, Lowe, Gordon, Rumley, Ann, Morris, Richard W., Whincup, Peter H., Rodriguez, Santiago, Ebrahim, Shah, Marmot, Michael G., Smith, George Davey, Lawlor, Debbie A., Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D., Day, Ian N. and Humphries, Steve E. (2011). Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip. Annals of Human Genetics, 75 (4), 456-467. doi: 10.1111/j.1469-1809.2011.00654.x

  • Zabaneh, Delilah, Kumari, , Meena, Sandhu, Manj, Wareham, Nick, Wainwright, Nick, Papamarkou, Theodore, Hopewell, Jemma, Clarke, Robert, Li, KaWah, Palmen, Jutta, Talmud, Philippa J., Kronenberg, Florian, Lamina, Claudia, Summerer, Monika, Paulweber, Bernhard, Price, Jackie, Fowkes, Gerry, Stewart, Marlene, Drenos, Fotios, Shah, Sonia, Shah, Tina, Casas, Juan-Pablo, Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D. and Humphries, Steve E. (2011). Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. Atherosclerosis, 217 (2), 447-451. doi: 10.1016/j.atherosclerosis.2011.04.015

  • Cannon, Christopher P., Shah, Sukrut, Dansky, Hayes M., Davidson, Michael, Brinton, Eliot A., Gotto Jr., Antonio M., Stepanavage, Michael, Liu, Sherry Xueyu, Gibbons, Patrice, Ashraf, Tanya B., Zafarino, Jennifer, Mitchel, Yale and Barter, Philip (2010). Safety of anacetrapib in patients with or at high risk for coronary heart disease. New England Journal of Medicine, 363 (25), 2406-2415. doi: 10.1056/NEJMoa1009744

  • Talmud, Philippa J., Drenos, Fotios, Shah, Sonia, Shah, Tina, Palmen, Jutta, Verzilli, Claudio, Gaunt, Tom R., Pallas, Jacky, Lovering, Ruth, Li, Kawah, Casas, Juan Pablo, Sofat, Reecha, Kumari, Meena, Rodriguez, Santiago, Johnson, Toby, Newhouse, Stephen J., Dominiczak, Anna, Samani, Nilesh J., Caulfield, Mark, Sever, Peter, Stanton, Alice, Shields, Denis C., Padmanabhan, Sandosh, Melander, Olle, Hastie, Claire, Delles, Christian, Ebrahim, Shah, Marmot, Michael G., Smith, George Davey ... Hingorani, Aroon D. (2009). Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. American Journal of Human Genetics, 85 (5), 628-642. doi: 10.1016/j.ajhg.2009.10.014

  • Risebro, Catherine A., Searles, Richelle G., Melville, Athalie A. D., Ehler, Elisabeth, Jina, Nipurna, Shah, Sonia, Pallas, Jacky, Hubank, Mike, Dillard, Miriam, Harvey, Natasha L., Schwartz, Robert J., Chien, Kenneth R., Oliver, Guillermo and Riley, Paul R. (2009). Prox1 maintains muscle structure and growth in the developing heart. Development, 136 (3), 495-505. doi: 10.1242/dev.030007

  • Cannon, Christopher P., Dansky, Hayes M., Davidson, Michael, Gotto Jr., Antonio M., Brinton, Eliot A., Gould, A. Lawrence, Stepanavage, Michael, Liu, Sherry Xueyu, Shah, Sukrut, Rubino, Joseph, Gibbons, Patrice, Hermanowski-Vosatka, Anne, Binkowitz, Bruce, Mitchel, Yale and Barter, Philip (2009). Design of the DEFINE trial: Determining the EFficacy and Tolerability of CETP INhibition with AnacEtrapib. American Heart Journal, 158 (4) doi: 10.1016/j.ahj.2009.07.028

  • Shah, Sonia H. and Pallas, Jacqueline A. (2009). Identifying differential exon splicing using linear models and correlation coefficients.. BMC bioinformatics, 10 (1) 26, 26.1-26.16. doi: 10.1186/1471-2105-10-26

  • Li, Charles Kwok-chong, Knopp, Paul, Moncrieffe, Halima, Singh, Bhanu, Shah, Sonia, Nagaraju, Kanneboyina, Varsani, Hemlata, Gao, Bin and Wedderburn, Lucy R. (2009). Overexpression of MHC class I heavy chain protein in young skeletal muscle leads to severe myositis: implications for juvenile myositis. American Journal of Pathology, 175 (3), 1030-1040. doi: 10.2353/ajpath.2009.090196

  • Barenco, M., Papouli, E., Shah, S., Brewer, D., Miller, C. J. and Hubank, M. (2009). rHVDM: An R package to predict the activity and targets of a transcription factor. Bioinformatics, 25 (3), 419-420. doi: 10.1093/bioinformatics/btn639

  • Morrison N., Wood A.J., Hancock D., Shah S., Hakes L., Gray T., Tiwari B., Kille P., Cossins A., Hegarty M., Allen M.J., Wilson W.H., Olive P., Last K., Kramer C., Bailhache T., Reeves J., Pallett D., Warne J., Nashar K., Parkinson H., Sansone S.-A., Rocca-Serra P., Stevens R., Snape J., Brass A. and Field D. (2006). Annotation of environmental OMICS data: Application to the transcriptomics domain. OMICS A Journal of Integrative Biology, 10 (2), 172-178. doi: 10.1089/omi.2006.10.172

Conference Publication

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors: