Overview
Clara Jiang is a postdoctoral research fellow at the Institute for Molecular Bioscience, the University of Queensland. Clara’s research focuses on using genomic and transcriptomic analysis to investigate the molecular impacts of drugs commonly prescribed for cardiovascular diseases, as well as using statistical genomic approaches to explore possible opportunities for drug repurposing. Clara graduated from the University of Queensland with Bachelor of Advanced Science (First Class Honours) in 2017, and was awarded the University Medal. Clara was awarded her PhD at the University of Queensland in 2021, where she utilised bioinformatic approaches and molecular experiments to decipher the genetic aetiology of breast cancer, specifically the regulatory role of transposons or ‘jumping genes’ in modulating the transcriptional landscape in the cancer state. Clara is also a UQ Wellness ambassador and an advocate for promoting equity, diversity and inclusion in academia.
Qualifications
- Doctor of Philosophy, The University of Queensland
Publications
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Journal Article: Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis
Jiang, Jiayue-Clara, Hu, Chenwen, McIntosh, Andrew M. and Shah, Sonia (2023). Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis. Translational Psychiatry, 13 (1) 110. doi: 10.1038/s41398-023-02403-8
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Other Outputs: Evaluation of transposon-derived regulation in breast cancer
Jiang, Jiayue (2021). Evaluation of transposon-derived regulation in breast cancer. PhD Thesis, School of Chemistry and Molecular Biosciences , The University of Queensland. doi: 10.14264/026a2eb
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Journal Article: Widespread exaptation of L1 transposons for transcription factor binding in breast cancer
Jiang, Jiayue-Clara, Rothnagel, Joseph A. and Upton, Kyle R. (2021). Widespread exaptation of L1 transposons for transcription factor binding in breast cancer. International Journal of Molecular Sciences, 22 (11) 5625, 1-21. doi: 10.3390/ijms22115625
Publications
Journal Article
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Jiang, Jiayue-Clara, Hu, Chenwen, McIntosh, Andrew M. and Shah, Sonia (2023). Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis. Translational Psychiatry, 13 (1) 110. doi: 10.1038/s41398-023-02403-8
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Widespread exaptation of L1 transposons for transcription factor binding in breast cancer
Jiang, Jiayue-Clara, Rothnagel, Joseph A. and Upton, Kyle R. (2021). Widespread exaptation of L1 transposons for transcription factor binding in breast cancer. International Journal of Molecular Sciences, 22 (11) 5625, 1-21. doi: 10.3390/ijms22115625
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Jiang, Jiayue-Clara, Rothnagel, Joseph A. and Upton, Kyle R. (2021). Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. Scientific Reports, 11 (1) 8083, 8083. doi: 10.1038/s41598-021-86395-9
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Serological antibody testing in the COVID-19 pandemic: their molecular basis and applications
Jiang, Jiayue-Clara and Zhang, Yan (2020). Serological antibody testing in the COVID-19 pandemic: their molecular basis and applications. Biochemical Society Transactions, 48 (6), 2851-2863. doi: 10.1042/bst20200744
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Jiang, Jiayue-Clara and Upton, Kyle R. (2019). Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines. Mobile DNA, 10 (1) 16, 16. doi: 10.1186/s13100-019-0158-3
Other Outputs
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Evaluation of transposon-derived regulation in breast cancer
Jiang, Jiayue (2021). Evaluation of transposon-derived regulation in breast cancer. PhD Thesis, School of Chemistry and Molecular Biosciences , The University of Queensland. doi: 10.14264/026a2eb
