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Associate Professor Joy Wolfram

Principal Research Fellow

School of Chemical Engineering
Faculty of Engineering, Architecture and Information Technology

Group Leader

Australian Institute for Bioengineering and Nanotechnology
j.wolfram@uq.edu.au

Overview

Associate Professor Joy Wolfram leads a nanomedicine and extracellular vesicle research program with the goal of developing innovative approaches that bring the next generation of treatments and diagnostics directly to the clinic. She has joint appointments in the School of Chemical Engineering and the Australian Institute for Bioengineering and Nanotechnology at The University of Queensland, Australia (#36 in Best Global Universities, U.S. News & World Report).

MISSION

1) Develop a new paradigm of therapeutics (using nanotechnology and cell products) to treat life-threatening diseases that are major causes of death globally, including cardiovascular disease, kidney disease, and breast cancer

2) Save lives by manufacturing at scale - Deliver national manufacturing innovation and a skilled workforce

3) Work with a multidisciplinary team and industry partners to position Australia as a global leader in extracellular vesicle medicine

Extracellular vesicles are small biomolecular packages (released locally and systemically) that are crucial for intercellular communication. Extracellular vesicles have promising potential to be leveraged and engineered to provide a paradigm shift in cell-free therapy. Unresolved challenges in the field include scalable manufacturing, understanding therapeutic/pathological mechanisms, and capacity to use extracellular vesicles for drug delivery. The Wolfram Laboratory is leveraging innovations in manufacturing, biological mechanisms, and drug loading of extracellular vesicles to develop therapeutics to alter the trajectory of disease, improve patient outcomes, and prolong healthy lifespan.

FOCUS AREAS

1) Developing improved methods for extracellular vesicle isolation from human biofluids

2) Designing hybrid drug delivery systems with extracellular vesicle and synthetic components for a ‘best-of-both-worlds’ approach to treat cardiovascular disease and chronic kidney disease

3) Understanding the role of extracellular vesicles in cancer immunoevasion and metastasis

The research program has resulted in more than 80 publications in journals, such as, Nature Nanotechnology, Materials Today, and Nature Reviews Materials. These publications have been cited 13,600 times (Google Scholar). The Wolfram Laboratory has collaborated with 160 universities and industry partners across 45 countries (Scopus). The research program has also been featured in more than 100 presentations at scientific meetings, including 78 invited talks and eight international keynote talks.

Associate Professor Wolfram is actively involved in community outreach and education, including her previous roles as the Chair of an education and outreach working group of the National Institutes of Health in the United States and the Associate Program Director of the PhD Program in Regenerative Sciences at Mayo Clinic (Best Hospital in the World, Newsweek). As a TED speaker, she strives to bring science to a wider audience.

She has received more than 30 awards from eight countries, including the 2016 Amgen Scholars Ten to Watch List (best and brightest up-and-comers in science and medicine across 42 countries), the 2019 Forbes 30 under 30 list in Health Care in the United States/Canada, the 2019 shortlist for the Nature Research Award for Inspiring Science (one of ten worldwide), and the 2021 Finnish Expatriate of the Year (past recipients include Nobel Memorial Prize winners, Millennium Technology Prize winners, and Formula 1 drivers). She is in the top 1% of researchers worldwide in the categories of ‘Biology & Biochemistry’ and ‘Pharmacology & Toxicology' (Essential Science Indicators, 2023).

Qualifications

  • Member, Global Young Academy, Global Young Academy
  • Doctor of Philosophy, University of the Chinese Academy of Science
  • Masters (Coursework), University of Helsinki*
  • Bachelor, University of Helsinki*

Publications

  • Journal Article: Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper

    Welsh, Joshua A., Goberdhan, Deborah C. I., O'Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrugger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, My G., Mohanty, Sujata, Moller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C., Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M., Brucale, Marco ... Allenby, Mark (2024). Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper. Journal of Extracellular Vesicles, 13 (2) e12404. doi: 10.1002/jev2.12404

  • Journal Article: High-throughput analysis of glycan sorting into extracellular vesicles

    Pendiuk Goncalves, Jenifer, Cruz Villarreal, Jorvani, Walker, Sierra A., Tan, Xuan Ning Sharon, Borges, Chad and Wolfram, Joy (2024). High-throughput analysis of glycan sorting into extracellular vesicles. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1871 (2) 119641, 119641. doi: 10.1016/j.bbamcr.2023.119641

  • Journal Article: Extracellular Vesicle and Lipoprotein Interactions

    Ghebosu, Raluca E., Pendiuk Goncalves, Jenifer and Wolfram, Joy (2023). Extracellular Vesicle and Lipoprotein Interactions. Nano Letters, 24 (1), 1-8. doi: 10.1021/acs.nanolett.3c03579

View all Publications

Grants

View all Grants

Supervision

  • Maximising the success of cancer immunotherapy by preventing extracellular vesicle hijacking of the immune system

    Doctor Philosophy

  • Mutation Targeting Therapy for Cancer with dCas9

    Doctor Philosophy

  • Characterizing the role of extracellular vesicle associated glycans on inflammation, cell growth and biodistribution

    Doctor Philosophy

View all Supervision

Available Projects

  • PhD projects in cardiovascular inflammation and cancer

    Please contact the Wolfram Laboratory if you are interested in PhD projects on:

    - Deveoping extracellular vesicle therapeutics for cardiovascular inflammation

    - Understanding the contribution of extracellular vesicles in breast cancer immunoevasion

View all Available Projects

Publications

Book Chapter

  • Nanomedicine activities in the United States and worldwide

    Borsoi, Carlotta, Wolfram, Joy and Ferrari, Mauro (2017). Nanomedicine activities in the United States and worldwide. Nanoscience and nanotechnology for human health. (pp. 21-50) edited by Bert Müller and Marcel Van de Voorde. Weinheim, Germany: Wiley-VCH . doi: 10.1002/9783527692057.ch3

  • Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems

    Suri, Krishna, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. (pp. 41-58) Elsevier Inc.. doi: 10.1016/B978-0-12-416603-5.00003-1

Journal Article

  • Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper

    Welsh, Joshua A., Goberdhan, Deborah C. I., O'Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrugger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, My G., Mohanty, Sujata, Moller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C., Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M., Brucale, Marco ... Allenby, Mark (2024). Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper. Journal of Extracellular Vesicles, 13 (2) e12404. doi: 10.1002/jev2.12404

  • High-throughput analysis of glycan sorting into extracellular vesicles

    Pendiuk Goncalves, Jenifer, Cruz Villarreal, Jorvani, Walker, Sierra A., Tan, Xuan Ning Sharon, Borges, Chad and Wolfram, Joy (2024). High-throughput analysis of glycan sorting into extracellular vesicles. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1871 (2) 119641, 119641. doi: 10.1016/j.bbamcr.2023.119641

  • Extracellular Vesicle and Lipoprotein Interactions

    Ghebosu, Raluca E., Pendiuk Goncalves, Jenifer and Wolfram, Joy (2023). Extracellular Vesicle and Lipoprotein Interactions. Nano Letters, 24 (1), 1-8. doi: 10.1021/acs.nanolett.3c03579

  • Entry and exit of extracellular vesicles to and from the blood circulation

    Iannotta, Dalila, A, Amruta, Kijas, Amanda W., Rowan, Alan E. and Wolfram, Joy (2023). Entry and exit of extracellular vesicles to and from the blood circulation. Nature Nanotechnology, 19 (1), 1-8. doi: 10.1038/s41565-023-01522-z

  • Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification

    Iannotta, Dalila, Amruta A., Lai, Andrew, Nair, Soumyalekshmi, Koifman, Na'ama, Lappas, Martha, Salomon, Carlos and Wolfram, Joy (2023). Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification. Small 2307240, 1-14. doi: 10.1002/smll.202307240

  • Transforming undergraduate laboratory courses with interlinked real-world challenges

    Iannotta, Dalila, Goncalves, Jenifer P., Ghebosu, Raluca E., Gopalakrishnan, Aswathi, Cooper-White, Justin and Wolfram, Joy (2023). Transforming undergraduate laboratory courses with interlinked real-world challenges. Trends in Biotechnology, 42 (1), 1-4. doi: 10.1016/j.tibtech.2023.10.006

  • Vasculature organotropism in drug delivery

    Amruta, A., Iannotta, Dalila, Cheetham, Seth W., Lammers, Twan and Wolfram, Joy (2023). Vasculature organotropism in drug delivery. Advanced Drug Delivery Reviews, 201 115054, 1-13. doi: 10.1016/j.addr.2023.115054

  • Extracellular vesicle lipids in cancer immunoevasion

    Chen, Siyu, Iannotta, Dalila, O'Mara, Megan L., Goncalves, Jenifer Pendiuk and Wolfram, Joy (2023). Extracellular vesicle lipids in cancer immunoevasion. Trends in Cancer, 9 (11), 883-886. doi: 10.1016/j.trecan.2023.08.006

  • Hyaluronic acid: An overlooked extracellular vesicle contaminant

    Goncalves, Jenifer P., Ghebosu, Raluca E., Tan, Xuan Ning Sharon, Iannotta, Dalila, Koifman, Na'ama and Wolfram, Joy (2023). Hyaluronic acid: An overlooked extracellular vesicle contaminant. Journal of Extracellular Vesicles, 12 (9) 12362, e12362. doi: 10.1002/jev2.12362

  • Reconstituted extracellular vesicles from human platelets decrease viral myocarditis in mice

    Beetler, Danielle J., Bruno, Katelyn A., Watkins, Molly M., Xu, Vivian, Chekuri, Isha, Giresi, Presley, Di Florio, Damian N., Whelan, Emily R., Edenfield, Brandy H., Walker, Sierra A., Morales-Lara, Andrea C., Hill, Anneliese R., Jain, Angita, Auda, Matthew E., Macomb, Logan P., Shapiro, Kathryn A., Keegan, Kevin C., Wolfram, Joy, Behfar, Atta, Stalboerger, Paul G., Terzic, Andre, Farres, Houssam, Cooper, Leslie T. and Fairweather, DeLisa (2023). Reconstituted extracellular vesicles from human platelets decrease viral myocarditis in mice. Small, 19 (49) 2303317, e2303317. doi: 10.1002/smll.202303317

  • Clinical translation of extracellular vesicles

    Ghodasara, Aayushi, Raza, Aun, Wolfram, Joy, Salomon, Carlos and Popat, Amirali (2023). Clinical translation of extracellular vesicles. Advanced Healthcare Materials, 12 (28) 2301010, e2301010. doi: 10.1002/adhm.202301010

  • Glycan node analysis detects varying glycosaminoglycan levels in melanoma-derived extracellular vesicles

    Pendiuk Goncalves, Jenifer, Walker, Sierra A., Aguilar Díaz de león, Jesús S., Yang, Yubo, Davidovich, Irina, Busatto, Sara, Sarkaria, Jann, Talmon, Yeshayahu, Borges, Chad R. and Wolfram, Joy (2023). Glycan node analysis detects varying glycosaminoglycan levels in melanoma-derived extracellular vesicles. International Journal of Molecular Sciences, 24 (10) 8506, 1-13. doi: 10.3390/ijms24108506

  • RAB27B drives a cancer stem cell phenotype in NSCLC cells through enhanced extracellular vesicle secretion

    Meneses, Kayleah M., Pandya, Prita, Lindemann, Jennifer A., Al-Qasrawi, Dania S., Argo, Ryan A., Weems, Celeste M., Beetler, Danielle J., Vijay, Geraldine V., Yan, Irene K., Wolfram, Joy, Patel, Tushar and Justilien, Verline (2023). RAB27B drives a cancer stem cell phenotype in NSCLC cells through enhanced extracellular vesicle secretion. Cancer Research Communications, 3 (4), 607-620. doi: 10.1158/2767-9764.crc-22-0425

  • Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells

    Bian, Xiaohui, Conley, Sabena M., Eirin, Alfonso, Zimmerman Zuckerman, Eric A., Smith, Anastasia L., Gowan, Cody C., Snow, Zachary K., Jarmi, Tambi, Farres, Houssam, Erben, Young M., Hakaim, Albert G., Dietz, Matthew A., Zubair, Abba C., Wyles, Saranya P., Wolfram, Joy V., Lerman, Lilach O. and Hickson, LaTonya J. (2023). Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells. Stem Cell Research and Therapy, 14 (1) 49, 49. doi: 10.1186/s13287-023-03269-9

  • Unraveling multilayered extracellular vesicles: Speculation on cause

    Broad, Kelly, Walker, Sierra A., Davidovich, Irina, Witwer, Kenneth, Talmon, Yeshayahu and Wolfram, Joy (2023). Unraveling multilayered extracellular vesicles: Speculation on cause. Journal of Extracellular Vesicles, 12 (2) e12309, e12309. doi: 10.1002/jev2.12309

  • Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

    Bruno, Maria Chiara, Cristiano, Maria Chiara, Celia, Christian, d'Avanzo, Nicola, Mancuso, Antonia, Paolino, Donatella, Wolfram, Joy and Fresta, Massimo (2022). Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis. ACS Nano, 16 (12), 19665-19690. doi: 10.1021/acsnano.2c06393

  • Sucrose-based cryoprotective storage of extracellular vesicles

    Walker, Sierra A., Davidovich, Irina, Yang, Yubo, Lai, Andrew, Goncalves, Jenifer Pendiuk, Deliwala, Vatsal, Busatto, Sara, Shapiro, Shane, Koifman, Na’ama, Salomon, Carlos, Talmon, Yeshayahu and Wolfram, Joy (2022). Sucrose-based cryoprotective storage of extracellular vesicles. Extracellular Vesicle, 1 100016, 100016. doi: 10.1016/j.vesic.2022.100016

  • Extracellular vesicles as personalized medicine

    Beetler, Danielle J., Di Florio, Damian N., Bruno, Katelyn A., Ikezu, Tsuneya, March, Keith L., Cooper, Leslie T., Wolfram, Joy and Fairweather, DeLisa (2022). Extracellular vesicles as personalized medicine. Molecular Aspects of Medicine, 91 101155, 1-14. doi: 10.1016/j.mam.2022.101155

  • Patients as biomedical researchers

    Liskey, Delaney, Cynkin, Laurie and Wolfram, Joy (2022). Patients as biomedical researchers. Trends in Molecular Medicine, 28 (12), 1022-1024. doi: 10.1016/j.molmed.2022.09.002

  • The cancer cell-derived extracellular vesicle glycocode in immunoevasion

    Goncalves, Jenifer P., Deliwala, Vatsal J., Kolarich, Daniel, Souza-Fonseca-Guimaraes, Fernando and Wolfram, Joy (2022). The cancer cell-derived extracellular vesicle glycocode in immunoevasion. Trends in Immunology, 43 (11), 864-867. doi: 10.1016/j.it.2022.09.004

  • Considerations for extracellular vesicle and lipoprotein interactions in cell culture assays

    Busatto, Sara, Yang, Yubo, Iannotta, Dalila, Davidovich, Irina, Talmon, Yeshayahu and Wolfram, Joy (2022). Considerations for extracellular vesicle and lipoprotein interactions in cell culture assays. Journal of Extracellular Vesicles, 11 (4) e12202, e12202. doi: 10.1002/jev2.12202

  • Extracellular vesicle glucose transporter-1 and glycan features in monocyte-endothelial inflammatory interactions

    Yang, Man, Walker, Sierra A., Aguilar Díaz de León, Jesús S., Davidovich, Irina, Broad, Kelly, Talmon, Yeshayahu, Borges, Chad R. and Wolfram, Joy (2022). Extracellular vesicle glucose transporter-1 and glycan features in monocyte-endothelial inflammatory interactions. Nanomedicine, 42 102515, 102515. doi: 10.1016/j.nano.2022.102515

  • Effects of adipose-derived biogenic nanoparticle-associated microrna-451a on toll-like receptor 4-induced cytokines

    Wang, Xinghua, Pham, Anthony, Kang, Lu, Walker, Sierra A., Davidovich, Irina, Iannotta, Dalila, Terkonda, Sarvam P., Shapiro, Shane, Talmon, Yeshayahu, Pham, Si and Wolfram, Joy (2022). Effects of adipose-derived biogenic nanoparticle-associated microrna-451a on toll-like receptor 4-induced cytokines. Pharmaceutics, 14 (1) 16, 16. doi: 10.3390/pharmaceutics14010016

  • Extracellular vesicle therapeutics from plasma and adipose tissue

    Iannotta, Dalila, Yang, Man, Celia, Christian, Di Marzio, Luisa and Wolfram, Joy (2021). Extracellular vesicle therapeutics from plasma and adipose tissue. Nano Today, 39 101159, 101159. doi: 10.1016/j.nantod.2021.101159

  • A simple and quick method for loading proteins in extracellular vesicles

    Busatto, Sara, Iannotta, Dalila, Walker, Sierra A., Di Marzio, Luisa and Wolfram, Joy (2021). A simple and quick method for loading proteins in extracellular vesicles. Pharmaceuticals, 14 (4) 356, 356. doi: 10.3390/ph14040356

  • Extracellular vesicles in cancer detection: hopes and hypes

    Hu, Tony, Wolfram, Joy and Srivastava, Sudhir (2021). Extracellular vesicles in cancer detection: hopes and hypes. Trends in Cancer, 7 (2), 122-133. doi: 10.1016/j.trecan.2020.09.003

  • Extracellular vesicles versus synthetic nanoparticles for drug delivery

    Witwer, Kenneth W. and Wolfram, Joy (2021). Extracellular vesicles versus synthetic nanoparticles for drug delivery. Nature Reviews Materials, 6 (2), 103-106. doi: 10.1038/s41578-020-00277-6

  • Education and outreach in physical sciences in oncology

    Walker, Sierra A., Pham, Anthony, Nizzero, Sara, Kim, Mingee, Riter, Bob, Bletz, Julie, Judge, Sheila, Phillips, Benette, Noble, Dorottya, Murray, Diana, Wetzel, Erin, Samson, Susan, McMahon, Mariah, Flink, Carl, Couch, Jennifer, Tomlin, Claire, Swanson, Kristin, Anderson, Alexander R. A., Odde, David, Shen, Haifa, Hughes, Shannon, Zahir, Nastaran, Enderling, Heiko and Wolfram, Joy (2021). Education and outreach in physical sciences in oncology. Trends in Cancer, 7 (1), 3-9. doi: 10.1016/j.trecan.2020.10.007

  • Extracellular vesicles for treatment of solid organ ischemia-reperfusion injury

    Ali, Mojahid, Pham, Anthony, Wang, Xinghua, Wolfram, Joy and Pham, Si (2020). Extracellular vesicles for treatment of solid organ ischemia-reperfusion injury. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20 (12), 3294-3307. doi: 10.1111/ajt.16164

  • Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein

    Busatto, Sara, Yang, Yubo, Walker, Sierra A., Davidovich, Irina, Lin, Wan-Hsin, Lewis-Tuffin, Laura, Anastasiadis, Panagiotis Z., Sarkaria, Jann, Talmon, Yeshayahu, Wurtz, Gregory and Wolfram, Joy (2020). Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein. Journal of Nanobiotechnology, 18 (1) 162, 162. doi: 10.1186/s12951-020-00722-2

  • Glycan node analysis of plasma-derived extracellular vesicles

    Walker, Sierra A., Aguilar Díaz De León, Jesús S., Busatto, Sara, Wurtz, Gregory A., Zubair, Abba C., Borges, Chad R. and Wolfram, Joy (2020). Glycan node analysis of plasma-derived extracellular vesicles. Cells, 9 (9) 5277, 1946. doi: 10.3390/cells9091946

  • Lipoprotein-based drug delivery

    Busatto, Sara, Walker, Sierra A., Grayson, Whisper, Pham, Anthony, Tian, Ming, Nesto, Nicole, Barklund, Jacqueline and Wolfram, Joy (2020). Lipoprotein-based drug delivery. Advanced drug delivery reviews, 159, 377-390. doi: 10.1016/j.addr.2020.08.003

  • Insights from nanomedicine into chloroquine efficacy against COVID-19

    Hu, Tony Y., Frieman, Matthew and Wolfram, Joy (2020). Insights from nanomedicine into chloroquine efficacy against COVID-19. Nature Nanotechnology, 15 (4), 247-249. doi: 10.1038/s41565-020-0674-9

  • Adipose-derived biogenic nanoparticles for suppression of inflammation

    Tian, Ming, Ticer, Taylor, Wang, Qikun, Walker, Sierra, Pham, Anthony, Suh, Annie, Busatto, Sara, Davidovich, Irina, Al-Kharboosh, Rawan, Lewis-Tuffin, Laura, Ji, Baoan, Quinones-Hinojosa, Alfredo, Talmon, Yeshayahu, Shapiro, Shane, Rueckert, Felix and Wolfram, Joy (2020). Adipose-derived biogenic nanoparticles for suppression of inflammation. Small, 16 (10) 1904064, 1-13. doi: 10.1002/smll.201904064

  • The solid progress of nanomedicine

    Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2

  • Extracellular vesicle-based drug delivery systems for cancer treatment

    Walker, Sierra, Busatto, Sara, Pham, Anthony, Tian, Ming, Suh, Annie, Carson, Kelsey, Quintero, Astrid, Lafrence, Maria, Malik, Hanna, Santana, Moises X and Wolfram, Joy (2019). Extracellular vesicle-based drug delivery systems for cancer treatment. Theranostics, 9 (26), 8001-8017. doi: 10.7150/thno.37097

  • Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles

    Nizzero, Sara, Li, Feng, Zhang, Guodong, Venuta, Alessandro, Borsoi, Carlotta, Mai, Junhua, Shen, Haifa, Wolfram, Joy, Li, Zheng, Blanco, Elvin and Ferrari, Mauro (2019). Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles. Acta Biomaterialia, 97, 501-512. doi: 10.1016/j.actbio.2019.08.002

  • Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

    Suh, Annie, Pham, Anthony, Cress, Mikel Jean, Pincelli, Thais, TerKonda, Sarvam P., Bruce, Alison J., Zubair, Abba C., Wolfram, Joy and Shapiro, Shane A. (2019). Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation. Ageing Research Reviews, 54 100933. doi: 10.1016/j.arr.2019.100933

  • Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9)

    Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (9), 902-902. doi: 10.1038/s41565-019-0538-3

  • Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9)

    Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (8), 811-811. doi: 10.1038/s41565-019-0523-x

  • On the issue of transparency and reproducibility in nanomedicine

    Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufés, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology, 14 (7), 629-635. doi: 10.1038/s41565-019-0496-9

  • Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles

    Busatto, Sara, Pham, Anthony, Suh, Annie, Shapiro, Shane and Wolfram, Joy (2019). Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles. Biomedical Microdevices, 21 (2) 46, 46. doi: 10.1007/s10544-019-0396-7

  • Clinical cancer nanomedicine

    Wolfram, Joy and Ferrari, Mauro (2019). Clinical cancer nanomedicine. Nano Today, 25, 85-98. doi: 10.1016/j.nantod.2019.02.005

  • Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid

    Busatto, Sara, Vilanilam, George, Ticer, Taylor, Lin, Wen-Lang, Dickson, Dennis, Shapiro, Shane, Bergese, Paolo and Wolfram, Joy (2018). Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid. Cells, 7 (12) 273, 273. doi: 10.3390/cells7120273

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Thery, Clotilde, Witwer, Kenneth W., Aikawa, Elena, Jose Alcaraz, Maria, Anderson, Johnathon D., Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K., Ayre, D. Craig, Bach, Jean-Marie, Bachurski, Daniel, Baharvand, Hossein, Balaj, Leonora, Baldacchino, Shawn, Bauer, Natalie N., Baxter, Amy A., Bebawy, Mary, Beckham, Carla, Zavec, Apolonija Bedina, Benmoussa, Abderrahim, Berardi, Anna C., Bergese, Paolo, Bielska, Ewa, Blenkiron, Cherie, Bobis-Wozowicz, Sylwia, Boilard, Eric, Boireau, Wilfrid ... Zuba-Surma, Ewa K. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles, 7 (1) 1535750, 1535750. doi: 10.1080/20013078.2018.1535750

  • Chloroquine and nanoparticle drug delivery: A promising combination

    Pelt, Joe, Busatto, Sara, Ferrari, Mauro, Thompson, E. Aubrey, Mody, Kabir and Wolfram, Joy (2018). Chloroquine and nanoparticle drug delivery: A promising combination. Pharmacology and Therapeutics, 191, 43-49. doi: 10.1016/j.pharmthera.2018.06.007

  • Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer

    Mu, Chaofeng, Wu, Xiaoyan, Zhou, Xinyu, Wolfram, Joy, Shen, Jianliang, Zhang, Dechen, Mai, Junhua, Xia, Xiaojun, Holder, Ashley M., Ferrari, Mauro, Liu, Xuewu and Shen, Haifa (2018). Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer. Clinical Cancer Research, 24 (19), 4900-4912. doi: 10.1158/1078-0432.CCR-17-3872

  • Extracellular vesicle therapeutics for liver disease

    Borrelli, David A., Yankson, Kiera, Shukla, Neha, Vilanilam, George, Ticer, Taylor and Wolfram, Joy (2018). Extracellular vesicle therapeutics for liver disease. Journal of Controlled Release, 273, 86-98. doi: 10.1016/j.jconrel.2018.01.022

  • A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells

    Liu, Haoran, Mai, Junhua, Shen, Jianliang, Wolfram, Joy, Li, Zhaoqi, Zhang, Guodong, Xu, Rong, Li, Yan, Mu, Chaofeng, Zu, Youli, Li, Xin, Lokesh, Ganesh L., Thiviyanathan, Varatharasa, Volk, David E., Gorenstein, David G., Ferrari, Mauro, Hu, Zhongbo and Shen, Haifa (2018). A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells. Theranostics, 8 (1), 31-44. doi: 10.7150/thno.21342

  • A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery

    Wolfram, Joy, Nizzero, Sara, Liu, Haoran, Li, Feng, Zhang, Guodong, Li, Zheng, Shen, Haifa, Blanco, Elvin and Ferrari, Mauro (2017). A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery. Scientific Reports, 7 (1) 13738. doi: 10.1038/s41598-017-14221-2

  • Contribution of Kupffer cells to liposome accumulation in the liver

    Samuelsson, Emma, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Contribution of Kupffer cells to liposome accumulation in the liver. Colloids and Surfaces B: Biointerfaces, 158, 356-362. doi: 10.1016/j.colsurfb.2017.07.014

  • Strategies for improving drug delivery: nanocarriers and microenvironmental priming

    Khalid, Ayesha, Persano, Stefano, Shen, Haifa, Zhao, Yuliang, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Strategies for improving drug delivery: nanocarriers and microenvironmental priming. Expert Opinion on Drug Delivery, 14 (7), 865-877. doi: 10.1080/17425247.2017.1243527

  • A liposome encapsulated ruthenium polypyridine complex as a theranostic platform for triple-negative breast cancer

    Shen, Jianliang, Kim, Han-Cheon, Wolfram, Joy, Mu, Chaofeng, Zhang, Wei, Liu, Haoran, Xie, Yan, Mai, Junhua, Zhang, Hang, Li, Zhi, Guevara, Maria, Mao, Zong-Wan and Shen, Haifa (2017). A liposome encapsulated ruthenium polypyridine complex as a theranostic platform for triple-negative breast cancer. Nano Letters, 17 (5), 2913-2920. doi: 10.1021/acs.nanolett.7b00132

  • Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles

    Shen, Jianliang, Liu, Haoran, Mu, Chaofeng, Wolfram, Joy, Zhang, Wei, Kim, Han-Cheon, Zhu, Guixian, Hu, Zhongbo, Ji, Liang-Nian, Liu, Xuewu, Ferrari, Mauro, Mao, Zong-Wan and Shen, Haifa (2017). Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles. Nanoscale, 9 (16), 5329-5341. doi: 10.1039/c7nr00377c

  • Taking the vehicle out of drug delivery

    Shen, Jianliang, Wolfram, Joy, Ferrari, Mauro and Shen, Haifa (2017). Taking the vehicle out of drug delivery. Materials Today, 20 (3), 95-97. doi: 10.1016/j.mattod.2017.01.013

  • Post-nano strategies for drug delivery: multistage porous silicon microvectors

    Venuta, Alessandro, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2017). Post-nano strategies for drug delivery: multistage porous silicon microvectors. Journal of Materials Chemistry B, 5 (2), 207-219. doi: 10.1039/C6TB01978A

  • Enzyme-responsive multistage vector for drug delivery to tumor tissue

    Mi, Yu, Wolfram, Joy, Mu, Chaofeng, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). Enzyme-responsive multistage vector for drug delivery to tumor tissue. Pharmacological Research, 113, 92-99. doi: 10.1016/j.phrs.2016.08.024

  • Label-free isothermal amplification assay for specific and highly sensitive colorimetric miRNA detection

    Persano, Stefano, Guevara, Maria L., Wolfram, Joy, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Pompa, Pier Paolo (2016). Label-free isothermal amplification assay for specific and highly sensitive colorimetric miRNA detection. ACS Omega, 1 (3), 448-455. doi: 10.1021/acsomega.6b00109

  • A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells

    Scott, Bronwyn, Shen, Jianliang, Nizzero, Sara, Boom, Kathryn, Persano, Stefano, Mi, Yu, Liu, Xuewu, Zhao, Yuliang, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Wolfram, Joy (2016). A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells. Pharmacological Research, 111, 413-421. doi: 10.1016/j.phrs.2016.07.005

  • Hesperetin liposomes for cancer therapy

    Wolfram, Joy, Scott, Bronwyn, Boom, Kathryn, Shen, Jianliang, Borsoi, Carlotta, Suri, Krishna, Grande, Rossella, Fresta, Massimo, Celia, Christian, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2016). Hesperetin liposomes for cancer therapy. Current Drug Delivery, 13 (5), 711-719. doi: 10.2174/1567201812666151027142412

  • A micro/nano composite for combination treatment of melanoma lung metastasis

    Mi, Yu, Mu, Chaofeng, Wolfram, Joy, Deng, Zaian, Hu, Tony Ye, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). A micro/nano composite for combination treatment of melanoma lung metastasis. Advanced Healthcare Materials, 5 (8), 936-946. doi: 10.1002/adhm.201500910

  • Multistage vector (MSV) therapeutics

    Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Multistage vector (MSV) therapeutics. Journal of Controlled Release, 219, 406-415. doi: 10.1016/j.jconrel.2015.08.010

  • Multistage vector delivery of sulindac and silymarin for prevention of colon cancer

    Scavo, Maria Principia, Gentile, Emanuela, Wolfram, Joy, Gu, Jianhua, Barone, Michele, Evangelopoulos, Michael, Martinez, Jonathan O., Liu, Xuewu, Celia, Christian, Tasciotti, Ennio, Vilar, Eduardo and Shen, Haifa (2015). Multistage vector delivery of sulindac and silymarin for prevention of colon cancer. Colloids and Surfaces B: Biointerfaces, 136, 694-703. doi: 10.1016/j.colsurfb.2015.10.005

  • Recent advances in discovering the role of CCL5 in metastatic breast cancer

    Khalid, Ayesha, Wolfram, Joy, Ferrari, Ilaria, Mu, Chaofeng, Mai, Junhua, Yang, Zhizhou, Zhao, Yuliang, Ferrari, Mauro, Ma, Xiaojing and Shen, Haifa (2015). Recent advances in discovering the role of CCL5 in metastatic breast cancer. Mini-Reviews in Medicinal Chemistry, 15 (13), 1063-1072. doi: 10.2174/138955751513150923094709

  • Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis

    Yang, Zhizhou, Sun, Zhaorui, Liu, Hongmei, Ren, Yi, Shao, Danbing, Zhang, Wei, Lin, Jinfeng, Wolfram, Joy, Wang, Feng and Nie, Shinan (2015). Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis. Molecular Medicine Reports, 12 (1), 1091-1097. doi: 10.3892/mmr.2015.3537

  • Protective effects of intestinal trefoil factor (ITF) on gastric mucosal epithelium through activation of extracellular signal-regulated kinase 1/2 (ERK1/2)

    Lin, Jinfeng, Sun, Zhaorui, Zhang, Wei, Liu, Hongmei, Shao, Danbing, Ren, Yi, Wen, Yanfang, Cao, Liping, Wolfram, Joy, Yang, Zhizhou and Nie, Shinan (2015). Protective effects of intestinal trefoil factor (ITF) on gastric mucosal epithelium through activation of extracellular signal-regulated kinase 1/2 (ERK1/2). Molecular and Cellular Biochemistry: an international journal for chemical biology in health and disease, 404 (1-2), 263-270. doi: 10.1007/s11010-015-2386-2

  • Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy

    Pasut, Gianfranco, Paolino, Donatella, Celia, Christian, Mero, Anna, Joseph, Adrian Steve, Wolfram, Joy, Cosco, Donato, Schiavon, Oddone, Shen, Haifa and Fresta, Massimo (2015). Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy. Journal of Controlled Release, 199, 106-113. doi: 10.1016/j.jconrel.2014.12.008

  • Porous silicon microparticles for delivery of siRNA therapeutics

    Shen, Jianliang, Wu, Xiaoyan, Lee, Yeonju, Wolfram, Joy, Yang, Zhizhou, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2015). Porous silicon microparticles for delivery of siRNA therapeutics. Journal of Visualized Experiments (95) e52075. doi: 10.3791/52075

  • Safety of nanoparticles in medicine

    Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2015). Safety of nanoparticles in medicine. Current Drug Targets, 16 (14), 1671-1681. doi: 10.2174/1389450115666140804124808

  • The nano-plasma interface: Implications of the protein corona

    Wolfram, Joy, Yang, Yong, Shen, Jianliang, Moten, Asad, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). The nano-plasma interface: Implications of the protein corona. Colloids and Surfaces B: Biointerfaces, 124, 17-24. doi: 10.1016/j.colsurfb.2014.02.035

  • Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy

    Shen, Jianliang, Kim, Han-Cheon, Mu, Chaofeng, Gentile, Emanuela, Mai, Junhua, Wolfram, Joy, Ji, Liang-Nian, Ferrari, Mauro, Mao, Zong-wan and Shen, Haifa (2014). Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy. Advanced Healthcare Materials, 3 (10), 1629-1637. doi: 10.1002/adhm.201400103

  • The impact of lubricants on the precision lapping process

    Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy, Wei, Zhongxian, Shen, Yuqiu and Yang, Zhizhou (2014). The impact of lubricants on the precision lapping process. Microscopy and Microanalysis, 20 (6), 1708-1714. doi: 10.1017/S1431927614013397

  • Polyarginine induces an antitumor immune response through binding to toll-like receptor 4

    Yang, Yong, Wolfram, Joy, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2014). Polyarginine induces an antitumor immune response through binding to toll-like receptor 4. Small, 10 (7), 1250-1254. doi: 10.1002/smll.201302887

  • Shrinkage of pegylated and non-pegylated liposomes in serum

    Wolfram, Joy, Suri, Krishna, Yang, Yong, Shen, Jianliang, Celia, Christian, Fresta, Massimo, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2014). Shrinkage of pegylated and non-pegylated liposomes in serum. Colloids and Surfaces B: Biointerfaces, 114, 294-300. doi: 10.1016/j.colsurfb.2013.10.009

  • Differences in the aerobic capacity of flight muscles between butterfly populations and species with dissimilar flight abilities

    Rauhamäki, Virve, Wolfram, Joy, Jokitalo, Eija, Hanski, Ilkka and Dahlhoff, Elizabeth P. (2014). Differences in the aerobic capacity of flight muscles between butterfly populations and species with dissimilar flight abilities. PLoS ONE, 9 (1) e78069, e78069. doi: 10.1371/journal.pone.0078069

  • Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics

    Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan and Shen, Haifa (2014). Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics. Theranostics, 4 (5), 487-497. doi: 10.7150/thno.8263

  • Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells

    Wolfram, Joy, Suri, Krishna, Huang, Yi, Molinaro, Roberto, Borsoi, Carlotta, Scott, Bronwyn, Boom, Kathryn, Paolino, Donatella, Fresta, Massimo, Wang, Jianghua, Ferrari, Mauro, Celia, Christian and Shen, Haifa (2014). Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells. Journal of Microencapsulation, 31 (5), 501-507. doi: 10.3109/02652048.2013.879932

  • Mechanistic features of nanodiamonds in the lapping of magnetic heads

    Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy and Yang, Zhizhou (2014). Mechanistic features of nanodiamonds in the lapping of magnetic heads. Scientific World Journal, 2014 326427. doi: 10.1155/2014/326427

  • Safety of nanoparticles in medicine

    Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). Safety of nanoparticles in medicine. Current Drug Targets, 15 (10) A001.

  • Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes

    Paolino, Donatella, Cosco, Donato, Gaspari, Marco, Celano, Marilena, Wolfram, Joy, Voce, Pasquale, Puxeddu, Efisio, Filetti, Sebastiano, Celia, Christian, Ferrari, Mauro, Russo, Diego and Fresta, Massimo (2014). Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes. Biomaterials, 35 (25), 7101-7109. doi: 10.1016/j.biomaterials.2014.04.088

  • Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane

    Yang, Yong, Wolfram, Joy, Shen, Jianliang, Zhao, Yuliang, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane. FEBS Letters, 587 (24), 3912-3920. doi: 10.1016/j.febslet.2013.10.041

  • Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells

    Celia, Christian, Trapasso, Elena, Locatelli, Marcello, Navarra, Michele, Ventura, Cinzia Anna, Wolfram, Joy, Carafa, Maria, Morittu, Valeria Maria, Britti, Domenico, Di Marzio, Luisa and Paolino, Donatella (2013). Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. Colloids and Surfaces B: Biointerfaces, 112, 548-553. doi: 10.1016/j.colsurfb.2013.09.017

  • Liposomal chemotherapeutics

    Gentile, Emanuela, Cilurzo, Felisa, Di Marzio, Luisa, Carafa, Maria, Ventura, Cinzia Anna, Wolfram, Joy, Paolino, Donatella and Celia, Christian (2013). Liposomal chemotherapeutics. Future Oncology, 9 (12), 1849-1859. doi: 10.2217/FON.13.146

  • High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics

    Shen, Jianliang, Xu, Rong, Mai, Junhua, Kim, Han-Cheon, Guo, Xiaojing, Qin, Guoting, Yang, Yong, Wolfram, Joy, Mu, Chaofeng, Xia, Xiaojun, Gu, Jianhua, Liu, Xuewu, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2013). High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics. ACS Nano, 7 (11), 9867-9880. doi: 10.1021/nn4035316

  • Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells

    Yang, Yong, Wolfram, Joy, Boom, Kathryn, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells. Cell Biochemistry and Function, 31 (5), 374-379. doi: 10.1002/cbf.2905

  • Polyethylenimine and chitosan carriers for the delivery of RNA interference effectors

    Molinaro, Roberto, Wolfram, Joy, Federico, Cinzia, Cilurzo, Felisa, Di Marzio, Luisa, Ventura, Cinzia A., Carafa, Maria, Celia, Christian and Fresta, Massimo (2013). Polyethylenimine and chitosan carriers for the delivery of RNA interference effectors. Expert Opinion on Drug Delivery, 10 (12), 1653-1668. doi: 10.1517/17425247.2013.840286

  • Hesperetin: An inhibitor of the transforming growth factor-β (TGF-β) signaling pathway

    Yang, Yong, Wolfram, Joy, Shen, Haifa, Fang, Xiaohong and Ferrari, Mauro (2012). Hesperetin: An inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. European Journal of Medicinal Chemistry, 58, 390-395. doi: 10.1016/j.ejmech.2012.10.028

Conference Publication

PhD and MPhil Supervision

Current Supervision

  • Maximising the success of cancer immunotherapy by preventing extracellular vesicle hijacking of the immune system

    Doctor Philosophy — Principal Advisor

    Other advisors:

  • Mutation Targeting Therapy for Cancer with dCas9

    Doctor Philosophy — Principal Advisor

  • Characterizing the role of extracellular vesicle associated glycans on inflammation, cell growth and biodistribution

    Doctor Philosophy — Principal Advisor

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • PhD projects in cardiovascular inflammation and cancer

    Please contact the Wolfram Laboratory if you are interested in PhD projects on:

    - Deveoping extracellular vesicle therapeutics for cardiovascular inflammation

    - Understanding the contribution of extracellular vesicles in breast cancer immunoevasion

This staff member is a UQ Expert for media in the following fields:

Nanomedicine, Nanoparticles, Breast cancer, Extracellular vesicles, Exosomes, Biotherapeutics, Scientific outreach, Biomanufacturing, Regenerative medicine, Bioseparation

They are happy to lend their expertise to your articles or broadcasts and share their research discoveries and insights with the community via media channels.

For additional assistance with story ideas, general advice and information or help with seeking further experts, please email the UQ Media Team or telephone (07) 3365 1120.

Links

ResearcherID: I-1574-2019

ORCID: 0000-0003-0579-9897

Scopus ID: 55376006600

Google Scholar ID: ZjBJci8AAAAJ

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