Howe, Stephanie L., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Zigman, Jeffrey M., Ngo, Shyuan T. and Steyn, Frederik J. (2023). Associations of postprandial ghrelin, liver‐expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis. European Journal of Neurology. doi: 10.1111/ene.16052
Journal Article: Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms
Lee, Aven, Henderson, Robert, Arachchige, Buddhika Jayakody, Robertson, Thomas and McCombe, Pamela Ann (2023). Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms. Journal of the Neurological Sciences, 452 120753, 120753. doi: 10.1016/j.jns.2023.120753
Journal Article: COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success
Shefner, Jeremy M., Al-Chalabi, Ammar, Andrews, Jinsy A., Chio, Adriano, De Carvalho, Mamede, Cockroft, Bettina M., Corcia, Philippe, Couratier, Philippe, Cudkowicz, Merit E., Genge, Angela, Hardiman, Orla, Heiman-Patterson, Terry, Henderson, Robert D., Ingre, Caroline, Jackson, Carlayne E., Johnston, Wendy, Lechtzin, Noah, Ludolph, Albert, Maragakis, Nicholas J., Miller, Timothy M., Mora Pardina, Jesus S., Petri, Susanne, Simmons, Zachary, Van Den Berg, Leonard H., Zinman, Lorne, Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Simkins, Tyrell J. ... Rudnicki, Stacy A. (2023). COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (5-6), 1-12. doi: 10.1080/21678421.2023.2216223
(2023–2024) Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
(2022) Motor Neurone Disease Research Institute of Australia Inc Linda Rynalski Bridge Funding Grant
(2021–2023) Motor Neurone Disease Research Institute of Australia Inc
Asymmetry and Vulnerability in Amyotrophic Lateral Sclerosis
(2019) Doctor Philosophy
Use of bioinformatics to decode disease heterogeneity in motor neuron disease
Doctor Philosophy
Survival and heterogeneity in Motor Neurone Disease
Doctor Philosophy
Biofluid biomarkers of amyotrophic lateral sclerosis
Holdom, Cory J., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A., Rogers, Mary-Louise and Ngo, Shyuan T. (2022). Biofluid biomarkers of amyotrophic lateral sclerosis. Neurodegenerative diseases biomarkers: towards translating research to clinical practice. (pp. 263-306) edited by Philip V. Peplow, Bridget Martinez and Thomas A. Gennarelli. New York, United States: Springer . doi: 10.1007/978-1-0716-1712-0_11
Henderson, R. D., Winhammar, J. M. and Rowe, D. B. (2007). Assessing disease progression. The Motor Neurone Disease Handbook. (pp. 144-154) edited by M. C. Kiernan. Pyrmont, Australia: Australasian Medical Publishing Company.
Collateral circulation imaging for arterial lesions of stroke
Henderson, R. D. (2003). Collateral circulation imaging for arterial lesions of stroke. Advances in neurology, Vol 92: Ischemic stroke. (pp. 71-74) edited by H.J.M. Barnett, J. Bogousslavsky and H. Meldrum. Philadelphia, PA, United States: Lippincott, Williams & Wilkins.
Howe, Stephanie L., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Zigman, Jeffrey M., Ngo, Shyuan T. and Steyn, Frederik J. (2023). Associations of postprandial ghrelin, liver‐expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis. European Journal of Neurology. doi: 10.1111/ene.16052
Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms
Lee, Aven, Henderson, Robert, Arachchige, Buddhika Jayakody, Robertson, Thomas and McCombe, Pamela Ann (2023). Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms. Journal of the Neurological Sciences, 452 120753, 120753. doi: 10.1016/j.jns.2023.120753
Shefner, Jeremy M., Al-Chalabi, Ammar, Andrews, Jinsy A., Chio, Adriano, De Carvalho, Mamede, Cockroft, Bettina M., Corcia, Philippe, Couratier, Philippe, Cudkowicz, Merit E., Genge, Angela, Hardiman, Orla, Heiman-Patterson, Terry, Henderson, Robert D., Ingre, Caroline, Jackson, Carlayne E., Johnston, Wendy, Lechtzin, Noah, Ludolph, Albert, Maragakis, Nicholas J., Miller, Timothy M., Mora Pardina, Jesus S., Petri, Susanne, Simmons, Zachary, Van Den Berg, Leonard H., Zinman, Lorne, Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Simkins, Tyrell J. ... Rudnicki, Stacy A. (2023). COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (5-6), 1-12. doi: 10.1080/21678421.2023.2216223
Tjokrowijoto, Priscilla, Phillips, Mia, Ceslis, Amelia, Henderson, Robert D., McCombe, Pamela A. and Robinson, Gail A. (2023). Sensitivity and specificity of the ECAS in identifying executive function and social cognition deficits in MND. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (5-6), 466-474. doi: 10.1080/21678421.2023.2188053
Holdom, Cory J., van Unnik, Jordi W. J., van Eijk, Ruben P. A., van den Berg, Leonard H., Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2023). Use of hip- versus wrist-based actigraphy for assessing functional decline and disease progression in patients with motor neuron disease. Journal of Neurology, 270 (5), 2597-2605. doi: 10.1007/s00415-023-11584-7
Katz, Matthew, Waddell, Leigh B., Yuen, Michaela, Bryen, Samantha J., Oates, Emily, Garton, Fleur C., Robertson, Thomas, Henderson, Robert David, Cooper, Sandra T. and McCombe, Pamela A. (2023). Case report: Adult-onset limb girdle muscular dystrophy in sibling pair due to novel homozygous LAMA2 missense variant. Frontiers in Neurology, 14 1055639. doi: 10.3389/fneur.2023.1055639
Phenotypic variability within the desminopathies: A case series of three patients
Yeow, Dennis, Katz, Matthew, Henderson, Robert, Prasad, Sandhir, Denman, Russell, Blum, Stefan, Davis, Mark, Robertson, Thomas and McCombe, Pamela (2023). Phenotypic variability within the desminopathies: A case series of three patients. Frontiers in Neurology, 13 1110934. doi: 10.3389/fneur.2022.1110934
Clinical and neurophysiological biomarkers of disease progression in amyotrophic lateral sclerosis
Hannaford, Andrew, Byth, Karen, Pavey, Nathan, Henderson, Robert D., Mathers, Susan, Needham, Merrilee, Schultz, David, Menon, Parvathi, Kiernan, Matthew C. and Vucic, Steve (2023). Clinical and neurophysiological biomarkers of disease progression in amyotrophic lateral sclerosis. Muscle and Nerve, 67 (1), 17-24. doi: 10.1002/mus.27736
Nona, Robert J., Xu, Zhouwei, Robinson, Gail A., Henderson, Robert D. and McCombe, Pamela A. (2022). Age of onset and length of survival of Queensland patients with amyotrophic lateral sclerosis: with details of subjects with early onset and subjects with long survival. Neurodegenerative Diseases, 1-18. doi: 10.1159/000528875
Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS
Chang, Jeryn, Shaw, Thomas B., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Fripp, Jurgen, Barth, Markus, Guo, Christine C., Ngo, Shyuan T. and Steyn, Frederik J. (2022). Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS. European Journal of Neurology, 30 (1), 57-68. doi: 10.1111/ene.15589
Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T
Chang, Jeryn, Steyn, Frederik, Ngo, Shyuan, Henderson, Robert, Guo, Christine, Bollmann, Steffen, Fripp, Jurgen, Barth, Markus and Shaw, Thomas (2022). Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T. Journal of Open Source Software, 7 (76), 4368. doi: 10.21105/joss.04368
HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis
Nona, R. J., Greer, J. M., Henderson, R. D. and McCombe, P. A. (2022). HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (1-2), 1-9. doi: 10.1080/21678421.2022.2078665
Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease
Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5
Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report
Katz, Matthew, Garton, Fleur C., Davis, Mark, Henderson, Robert D. and McCombe, Pamela A. (2022). Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report. Frontiers in Neurology, 13 868655, 868655. doi: 10.3389/fneur.2022.868655
Hop, Paul J., Zwamborn, Ramona A.J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J.F.A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H.P., van Eijk, Kristel R., Moisse, Matthieu, Baird, Denis, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14 (633) eabj0264, 1-15. doi: 10.1126/scitranslmed.abj0264
Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1
Restuadi, Restuadi, Steyn, Frederik J., Kabashi, Edor, Ngo, Shyuan T., Cheng, Fei-Fei, Nabais, Marta F., Thompson, Mike J., Qi, Ting, Wu, Yang, Henders, Anjali K., Wallace, Leanne, Bye, Chris R., Turner, Bradley J., Ziser, Laura, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Schultz, David, Kiernan, Matthew C., van Rheenen, Wouter, van den Berg, Leonard H., Veldink, Jan H., Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F., Henderson, Robert D., Wray, Naomi R., Giacomotto, Jean and Garton, Fleur C. (2022). Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Medicine, 14 (1) 7, 7. doi: 10.1186/s13073-021-01006-6
van Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1
Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE
Caggiano, Christa, Celona, Barbara, Garton, Fleur, Mefford, Joel, Black, Brian L., Henderson, Robert, Lomen-Hoerth, Catherine, Dahl, Andrew and Zaitlen, Noah (2021). Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE. Nature Communications, 12 (1) 2717. doi: 10.1038/s41467-021-22901-x
Holdom, Cory J., Janse van Mantgem, Mark R., van Eijk, Ruben P.A., Howe, Stephanie L., van den Berg, Leonard H., McCombe, Pamela A., Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2021). Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis. European Journal of Neurology, 28 (11) ene.15003, 3615-3625. doi: 10.1111/ene.15003
Henderson, Robert D., Agosti, Jan M., McCombe, Pamela A., Thorpe, Kathryn, Heggie, Susan, Heshmat, Saman, Appleby, Mark W., Ziegelaar, Brian W., Crowe, David T. and Redlich, Garry L. (2021). Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis. Medicine, 100 (42), e27421. doi: 10.1097/MD.0000000000027421
Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials
Henderson, Robert D. and Devine, Matthew S. (2021). Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials. Journal of Neurology, Neurosurgery and Psychiatry, 93 (1), 3-3. doi: 10.1136/jnnp-2021-327948
MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease
Vucic, Steve, Wray, Naomi, Henders, Anjali, Henderson, Robert D., Talman, Paul, Mathers, Susan, Bellgard, Matthew, Aoun, Samar, Birks, Carol, Thomas, Gethin, Hansen, Catherine, Thomas, Geoff, Hogden, Anne, Needham, Merrilee, Schultz, David, Soulis, Tina, Sheean, Bec, Milne, Jane, Rowe, Dominic, Zoing, Margie and Kiernan, Matthew C (2021). MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1980889
Holdom, Cory J., Ngo, Shyuan T., McCombe, Pamela A., Henderson, Robert D. and Steyn, Frederik J. (2021). Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (1-2), 1-7. doi: 10.1080/21678421.2021.1918721
McGill, R.B., Steyn, F.J., Ngo, S.T., Thorpe, K.A., Heggie, S., Henderson, R.D., Mccombe, P.A. and Woodruff, T.M. (2021). Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1964531
Lee, Aven, Arachchige, Buddhika Jayakody, Henderson, Robert, Aylward, James and McCombe, Pamela Ann (2021). Elevated levels of homocysteinesulfinic acid in the plasma of patients with amyotrophic lateral sclerosis: a potential source of excitotoxicity?. Neurodegenerative Diseases, 20 (5-6), 200-206. doi: 10.1159/000517964
Restuadi, Restuadi, Garton, Fleur C., Benyamin, Beben, Lin, Tian, Williams, Kelly L., Vinkhuyzen, Anna, van Rheenen, Wouter, Zhu, Zhihong, Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Visscher, Peter M., Needham, Merrilee, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Wray, Naomi R. and McRae, Allan F. (2021). Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia. European Journal of Human Genetics, 30 (5), 1-8. doi: 10.1038/s41431-021-00885-y
Nabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5
Mizrahi, David, Park, Susanna B., Li, Tiffany, Timmins, Hannah C., Trinh, Terry, Au, Kimberley, Battaglini, Eva, Wyld, David, Henderson, Robert D., Grimison, Peter, Ke, Helen, Geelan-Small, Peter, Marker, Julie, Wall, Brian and Goldstein, David (2021). Hemoglobin, body mass index, and age as risk factors for Paclitaxel- and Oxaliplatin-induced peripheral neuropathy. JAMA Network Open, 4 (2) e2036695, 1-14. doi: 10.1001/jamanetworkopen.2020.36695
Ghrelin as a treatment for amyotrophic lateral sclerosis
Ngo, Shyuan T., Wang, Hao, Henderson, Robert D., Bowers, Cyril and Steyn, Frederik J. (2021). Ghrelin as a treatment for amyotrophic lateral sclerosis. Journal of Neuroendocrinology, 33 (7) e12938, 1-10. doi: 10.1111/jne.12938
Lee, John D., Heshmat, Saman, Heggie, Susan, Thorpe, Kathryn A., McCombe, Pamela A. and Henderson, Robert D. (2021). Clinical and electrophysiological examination of pinch strength in patients with amyotrophic lateral sclerosis. Muscle and Nerve, 63 (1) mus.27111, 108-113. doi: 10.1002/mus.27111
Disorders of sleep and wakefulness in amyotrophic lateral sclerosis (ALS): a systematic review
Lucia, Diana, McCombe, Pamela A., Henderson, Robert D. and Ngo, Shyuan T. (2020). Disorders of sleep and wakefulness in amyotrophic lateral sclerosis (ALS): a systematic review. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22 (3-4), 1-9. doi: 10.1080/21678421.2020.1844755
The spectrum of language impairments in amyotrophic lateral sclerosis
Ceslis, Amelia, Argall, Rosemary, Henderson, Robert D., McCombe, Pamela A. and Robinson, Gail A. (2020). The spectrum of language impairments in amyotrophic lateral sclerosis. Cortex, 132, 349-360. doi: 10.1016/j.cortex.2020.09.003
Elevated plasma levels of D-serine in some patients with amyotrophic lateral sclerosis
Lee, Aven, Arachchige, Buddhika Jayakody, Henderson, Robert, Pow, David, Reed, Sarah, Aylward, James and McCombe, Pamela Ann (2020). Elevated plasma levels of D-serine in some patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22 (3-4), 206-210. doi: 10.1080/21678421.2020.1832120
Iacoangeli, Alfredo, Lin, Tian, Al Khleifat, Ahmad, Jones, Ashley R., Opie-Martin, Sarah, Coleman, Jonathan R.I., Shatunov, Aleksey, Sproviero, William, Williams, Kelly L., Garton, Fleur, Restuadi, Restuadi, Henders, Anjali K., Mather, Karen A., Needham, Merilee, Mathers, Susan, Nicholson, Garth A., Rowe, Dominic B., Henderson, Robert, McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Schultz, David, Sachdev, Perminder S., Newhouse, Stephen J., Proitsi, Petroula, Fogh, Isabella, Ngo, Shyuan T., Dobson, Richard J.B., Wray, Naomi R. ... Al-Chalabi, Ammar (2020). Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease genetics. Cell Reports, 33 (4) 108323, 1-9. doi: 10.1016/j.celrep.2020.108323
Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis
Steyn, Frederik J., Li, Rui, Kirk, Siobhan E., Tefera, Tesfaye W, Xie, Teresa Y., Tracey, Timothy J., Kelk, Dean, Wimberger, Elyse, Garton, Fleur C., Roberts, Llion, Chapman, Sarah E., Coombes, Jeff S., Leevy, W. Matthew, Ferri, Alberto, Valle, Cristiana, René, Frédérique, Loeffler, Jean-Philippe, McCombe, Pamela A., Henderson, Robert D. and Ngo, Shyuan T. (2020). Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis. Brain Communications, 2 (2) fcaa154, fcaa154. doi: 10.1093/braincomms/fcaa154
What do we know about the variability in survival of patients with amyotrophic lateral sclerosis?
McCombe, Pamela A., Garton, Fleur C., Katz, Matthew, Wray, Naomi R. and Henderson, Robert D. (2020). What do we know about the variability in survival of patients with amyotrophic lateral sclerosis?. Expert Review of Neurotherapeutics, 20 (9), 921-941. doi: 10.1080/14737175.2020.1785873
Alruwaili, Ashwag R., Pannek, Kerstin, Henderson, Robert D., Gray, Marcus, Kurniawan, Nyoman D. and McCombe, Pamela A. (2020). Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis. BMC Medical Imaging, 20 (1) 90, 90. doi: 10.1186/s12880-020-00489-w
A proposal for new diagnostic criteria for ALS
Shefner, Jeremy M., Al-Chalabi, Ammar, Baker, Mark R., Cui, Li-Ying, de Carvalho, Mamede, Eisen, Andrew, Grosskreutz, Julian, Hardiman, Orla, Henderson, Robert, Matamala, Jose Manuel, Mitsumoto, Hiroshi, Paulus, Walter, Simon, Neil, Swash, Michael, Talbot, Kevin, Turner, Martin R., Ugawa, Yoshikazu, van den Berg, Leonard H., Verdugo, Renato, Vucic, Steven, Kaji, Ryuji, Burke, David and Kiernan, Matthew C. (2020). A proposal for new diagnostic criteria for ALS. Clinical Neurophysiology, 131 (8), 1975-1978. doi: 10.1016/j.clinph.2020.04.005
Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls
Mohanty, Lipsa, Henderson, Robert D., McCombe, Pamela A. and Lee, Aven (2020). Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls. Amyotrophic lateral sclerosis & frontotemporal degeneration, 21 (7-8), 1-4. doi: 10.1080/21678421.2020.1779303
Katz, Matthew, Davis, Mark, Garton, Fleur C., Henderson, Robert, Bharti, Vanda, Wray, Naomi and McCombe, Pamela (2020). Mutations in heat shock protein beta-1 (HSPB1) are associated with a range of clinical phenotypes related to different patterns of motor neuron dysfunction: a case series. Journal of the Neurological Sciences, 413 116809, 116809. doi: 10.1016/j.jns.2020.116809
The peripheral immune system and amyotrophic lateral sclerosis
McCombe, Pamela A., Lee, John D., Woodruff, Trent M. and Henderson, Robert D. (2020). The peripheral immune system and amyotrophic lateral sclerosis. Frontiers in Neurology, 11 279, 279. doi: 10.3389/fneur.2020.00279
Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth ... Wray, Naomi R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine, 5 (1) 10, 1-9. doi: 10.1038/s41525-020-0118-3
ALS in Danish Registries : Heritability and links to psychiatric and cardiovascular disorders
Trabjerg, Betina B., Garton, Fleur C., van Rheenen, Wouter, Fang, Fang, Henderson, Robert D., Mortensen, Preben Bo, Agerbo, Esben and Wray, Naomi R. (2020). ALS in Danish Registries : Heritability and links to psychiatric and cardiovascular disorders. Neurology Genetics, 6 (2) e398, e398. doi: 10.1212/nxg.0000000000000398
Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels
Lee, Aven, Arachchige, Buddhika Jayakody, Reed, Sarah, Henderson, Robert, Aylward, James and McCombe, Pamela Ann (2020). Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. Journal of the Neurological Sciences, 409 116589, 116589. doi: 10.1016/j.jns.2019.116589
Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis
McGill, Raquel B., Steyn, Frederik J., Ngo, Shyuan T., Thorpe, Kathryn A., Heggie, Susan, Ruitenberg, Marc J., Henderson, Robert D., McCombe, Pamela A. and Woodruff, Trent M. (2020). Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis. Brain Communications, 2 (1) fcaa013, fcaa013. doi: 10.1093/braincomms/fcaa013
Progression and survival of patients with motor neuron disease relative to their fecal microbiota
Ngo, Shyuan T., Restuadi, Restuadi, McCrea, Allan F., Van Eijk, Ruben P., Garton, Fleur, Henderson, Robert D., Wray, Naomi R., McCombe, Pamela A. and Steyn, Frederik J. (2020). Progression and survival of patients with motor neuron disease relative to their fecal microbiota. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21 (7-8), 1-14. doi: 10.1080/21678421.2020.1772825
Long-term follow-up of patients with myasthenia gravis treated with low-dose rituximab
Chan, Fiona, Swayne, Andrew, Gillis, David, Walsh, Michael, Henderson, Robert D., McCombe, Pamela A., Wong, Richard C. and Blum, Stefan (2019). Long-term follow-up of patients with myasthenia gravis treated with low-dose rituximab. Journal of Neurology, Neurosurgery and Psychiatry, 90 (8), 1-2. doi: 10.1136/jnnp-2018-319410
McCrary, J. Matt, Goldstein, David, Wyld, David, Henderson, Robert, Lewis, Craig R. and Park, Susanna B. (2019). Mobility in survivors with chemotherapy-induced peripheral neuropathy and utility of the 6-min walk test. Journal of Cancer Survivorship, 13 (4), 495-502. doi: 10.1007/s11764-019-00769-7
Gut microbiota in ALS: possible role in pathogenesis?
McCombe, Pamela A., Henderson, Robert D., Lee, Aven, Lee, John D., Woodruff, Trent M., Restuadi, Restuadi, McRae, Allan, Wray, Naomi R., Ngo, Shyuan and Steyn, Frederik J. (2019). Gut microbiota in ALS: possible role in pathogenesis?. Expert Review of Neurotherapeutics, 19 (9), 1-21. doi: 10.1080/14737175.2019.1623026
Ngo, Shyuan T., Van Eijk, Ruben P. A., Chachay, V. , Van Den Berg, Leonard H., Mccombe, Pamela A., Henderson, Robert D. and Steyn, Frederik J. (2019). Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20 (7-8), 1-9. doi: 10.1080/21678421.2019.1621346
Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies
Merkies, Ingemar S.J., van Schaik, Ivo N., Léger, Jean-Marc, Bril, Vera, van Geloven, Nan, Hartung, Hans-Peter, Lewis, Richard A., Sobue, Gen, Lawo, John-Philip, Durn, Billie L., Cornblath, David R., De Bleecker, Jan L., Sommer, Claudia, Robberecht, Wim, Saarela, Mika, Kamienowski, Jerzy, Stelmasiak, Zbigniew, Tackenberg, Björn, Mielke, Orell, Sabet, A., George, K., Roberts, L., Carne, R., Blum, S., Henderson, R., Van Damme, P., Demeestere, J., Larue, S., D'Amour, C. ... Zwolińska, G. (2019). Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies. Journal of the Peripheral Nervous System, 24 (1), 48-55. doi: 10.1111/jns.12302
Mielke, Orell, Bril, Vera, Cornblath, David R., Lawo, John-Philip, van Geloven, Nan, Hartung, Hans-Peter, Lewis, Richard A., Merkies, Ingemar S.J., Sobue, Gen, Durn, Billie, Shebl, Amgad, van Schaik, Ivo N., Sabet, A., George, K., Roberts, L., Carne, R., Blum, S., Henderson, R., Van Damme, P., Demeestere, J., Larue, S., D'Amour, C., Kunc, P., Valis, M., Sussova, J., Kalous, T., Talab, R., Bednar, M., Toomsoo, T. ... Gable, K. (2019). Restabilization treatment after intravenous immunoglobulin withdrawal in chronic inflammatory demyelinating polyneuropathy: Results from the pre-randomization phase of the Polyneuropathy And Treatment with Hizentra study. Journal of the Peripheral Nervous System, 24 (1), 72-79. doi: 10.1111/jns.12303
Alruwaili, Ashwag R., Pannek, Kerstin, Henderson, Robert D., Gray, Marcus, Kurniawan, Nyoman D. and McCombe, Pamela A. (2019). Tract integrity in amyotrophic lateral sclerosis: 6–month evaluation using MR diffusion tensor imaging. BMC Medical Imaging, 19 (1) 19, 19. doi: 10.1186/s12880-019-0319-3
Intravenous versus subcutaneous immunoglobulin – Authors' reply
van Schaik, Ivo N, Mielke, Orell, Sabet, Arman, George, Koshy, Roberts, Leslie, Carne, Ross, Blum, Stefan, Henderson, Robert, Van Damme, Philip, Demeestere, Jelle, Larue, Sandrine, Pinard D'Amour, Catherine-Andree, Bril, Vera, Breiner, Ari, Kunc, Pavel, Valis, Martin, Sussova, Jana, Kalous, Tomas, Talab, Radomir, Bednar, Michal, Toomsoo, Toomas, Rubanovits, Inna, Gross-Paju, Katrin, Sorro, Ulvi, Saarela, Mika, Auranen, Mari, Pouget, Jean, Attarian, Shahram, Le Masson, Gwendal ... Mielke, Orell (2018). Intravenous versus subcutaneous immunoglobulin – Authors' reply. The Lancet Neurology, 17 (5), 393-394. doi: 10.1016/S1474-4422(18)30109-1
Hypermetabolism in ALS is associated with greater functional decline and shorter survival
Steyn, Frederik J., Ioannides, Zara A., van Eijk, Ruben P. A., Heggie, Susan, Thorpe, Kathryn A., Ceslis, Amelia, Heshmat, Saman, Henders, Anjali K., Wray, Naomi R., van den Berg, Leonard H., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2018). Hypermetabolism in ALS is associated with greater functional decline and shorter survival. Journal of Neurology, Neurosurgery, and Psychiatry, 89 (10), jnnp-2017. doi: 10.1136/jnnp-2017-317887
Human cerebral evolution and the clinical syndrome of amyotrophic lateral sclerosis
Henderson, Robert D., Garton, Fleur C., Kiernan, Matthew C., Turner, Martin R. and Eisen, Andrew (2018). Human cerebral evolution and the clinical syndrome of amyotrophic lateral sclerosis. JNNP Online, 90 (5), jnnp-2017. doi: 10.1136/jnnp-2017-317245
Alruwaili, A. R., Pannek, K., Coulthard, A., Henderson, R., Kurniawan, N. D. and McCombe, P. (2018). A combined tract-based spatial statistics and voxel-based morphometry study of the first MRI scan after diagnosis of amyotrophic lateral sclerosis with subgroup analysis. Journal of Neuroradiology, 45 (1), 41-48. doi: 10.1016/j.neurad.2017.03.007
Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects
Xu, Zhouwei, Lee, Aven, Nouwens, Amanda, David Henderson, Robert and Mccombe, Pamela Ann (2018). Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19 (5-6), 1-15. doi: 10.1080/21678421.2018.1433689
McCombe, Pamela A., Ngo, Shyuan T., Guo, Christine Cong, Fazlollahi, Amir, Bollmann, Saskia, Wang, Liting, Hu, Xintao, Barth, Markus, Salvado, Olivier, Davis, Mark, Ceslis, Amelia, Robinson, Gail, Henderson, Robert D. and Steyn, Frederik J. (2018). Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction. Journal of Neurology, Neurosurgery and Psychiatry, 90 (8), 952-954. doi: 10.1136/jnnp-2018-318823
van Schaik, Ivo N., Bril, Vera, van Geloven, Nan, Hartung, Hans-Peter, Lewis, Richard A., Sobue, Gen, Lawo, John-Philip, Praus, Michaela, Mielke, Orell, Durn, Billie L., Cornblath, David R., Merkies, Ingemar S. J., Sabet, A., George, K., Roberts, L., Carne, R., Blum, S., Henderson, R., Van Damme, P., Demeestere, J., Larue, S., D'Amour, C., Bril, V., Breiner, A., Kunc, P., Valis, M., Sussova, J., Kalous, T., Talab, R. ... on behalf of the PATH study group (2018). Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet Neurology, 17 (1), 35-46. doi: 10.1016/S1474-4422(17)30378-2
The utility of FDG-PET in complex neurological conditions
Ioannides, Zara A., Thomas, Paul, Langguth, Daman, Kubler, Paul and Henderson, Robert D. (2017). The utility of FDG-PET in complex neurological conditions. Internal Medicine Journal, 47 (12), 1460-1462. doi: 10.1111/imj.13638
Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1
Ngo, Shyuan T., Mi, Jia D., Henderson, Robert D., McCombe, Pamela A. and Steyn, Frederik J. (2017). Exploring targets and therapies for amyotrophic lateral sclerosis: current insights into dietary interventions. Degenerative Neurological and Neuromuscular Disease, 7, 95-108. doi: 10.2147/DNND.S120607
Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302
Ioannides, Z. A., Steyn, F. J., Henderson, R. D., McCombe, P. A. and Ngo, S. T. (2017). Predictions of resting energy expenditure in amyotrophic lateral sclerosis are greatly impacted by reductions in fat free mass. Cogent Medicine, 4 (1), 1343000. doi: 10.1080/2331205X.2017.1343000
Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity
McCombe, P. A., Wray, N. R. and Henderson, R. D. (2017). Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity. Expert Review of Neurotherapeutics, 17 (6), 561-577. doi: 10.1080/14737175.2017.1273772
Xu, Zhouwei, Alruwaili, Ashwag Rafea S., Henderson, Robert David and McCombe, Pamela Ann (2017). Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival. Journal of the Neurological Sciences, 376, 16-23. doi: 10.1016/j.jns.2017.02.061
Anthropometric measures are not accurate predictors of fat mass in ALS
Ioannides, Zara A., Steyn, Frederik J., Henderson, Robert D., Mccombe, Pamela A. and Ngo, Shyuan T. (2017). Anthropometric measures are not accurate predictors of fat mass in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18 (7-8), 486-491. doi: 10.1080/21678421.2017.1317811
Peripheral nerve diffusion tensor imaging as a measure of disease progression in ALS
Simon, Neil G., Lagopoulos, Jim, Paling, Sita, Pfluger, Casey, Park, Susanna B., Howells, James, Gallagher, Thomas, Kliot, Michel, Henderson, Robert D., Vucic, Steve and Kiernan, Matthew (2017). Peripheral nerve diffusion tensor imaging as a measure of disease progression in ALS. Journal of Neurology, 264 (5), 882-890. doi: 10.1007/s00415-017-8443-x
Assessment of motor units in neuromuscular disease
Henderson, Robert D. and McCombe, Pamela A. (2017). Assessment of motor units in neuromuscular disease. Neurotherapeutics, 14 (1), 69-77. doi: 10.1007/s13311-016-0473-z
Xu, Zhouwei, Henderson, Robert David, David, Michael and McCombe, Pamela Ann (2016). Neurofilaments as biomarkers for amyotrophic lateral sclerosis: a systematic review and meta-analysis. PLoS ONE, 11 (10) e0164625, e0164625. doi: 10.1371/journal.pone.0164625
Ioannides, Z. A., Ngo, S. T., Henderson, R. D., McCombe, P. A. and Steyn, F. J. (2016). Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression. Neurodegenerative Diseases, 15 (5-6), 382-397. doi: 10.1159/000446502
Talman, Paul, Thi Duong, Vucic, Steve, Mathers, Susan, Venkatesh, Svetha, Henderson, Robert, Rowe, Dominic, Schultz, David, Edis, Robert, Needham, Merrilee, Macdonnell, Richard, McCombe, Pamela, Birks, Carol and Kiernan, Matthew (2016). Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort. BMJ Open, 6 (9) e012054, e012054. doi: 10.1136/bmjopen-2016-012054
Re-activation of varicella zoster virus associated with anterior spinal cord stroke in pregnancy
McNamara, John F., Paterson, David L., Allworth, Anthony, Presneill, Jeffrey, O'Connell, Paul and Henderson, Robert D. (2016). Re-activation of varicella zoster virus associated with anterior spinal cord stroke in pregnancy. Infectious Diseases, 48 (9), 705-707. doi: 10.1080/23744235.2016.1185535
A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma
McCombe, Pamela, Raj, Meenakshi, Henderson, Robert and Blum, Stefan (2016). A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma. Journal of Clinical Neuromuscular Disease, 17 (3), 129-134. doi: 10.1097/CND.0000000000000101
Devine, Matthew S., Ballard, Emma, O'Rourke, Peter, Kiernan, Matther C., Mccombe, Pamela A. and Henderson, Robert D. (2015). Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17 (3-4), 1-7. doi: 10.3109/21678421.2015.1125502
Neurological disorders that may deteriorate with intensive physical rehabilitation
Ioannides, Z. A., McGill, J., Robertson, T. and Henderson, R. D. (2015). Neurological disorders that may deteriorate with intensive physical rehabilitation. Internal Medicine Journal, 45 (11), 1193-1195. doi: 10.1111/imj.12903
Ngo, S. T., Steyn, F. J., Huang, L., Mantovani, S., Pfluger, C. M. M., Woodruff, T. M., O'Sullivan, J. D., Henderson, R. D. and McCombe, P. A. (2015). Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 357 (1-2), 22-27. doi: 10.1016/j.jns.2015.06.053
Ioannides, Z. A., Henderson, R. D., Robertson, T., Davis, M. and McCombe, P. A. (2015). When does ALS start? A novel SOD-1 p.Gly142Arg mutation causing motor neurone disease with prominent premorbid cramps and spasms. Journal of Neurology, Neurosurgery and Psychiatry, 87 (9), 1031-1032. doi: 10.1136/jnnp-2015-311582
Raffelt, David A., Smith, Robert E., Ridgway, Gerard R., Tournier, J-Donald, Vaughan, David N., Rose, Stephen, Henderson, Robert and Connelly, Alan (2015). Connectivity-based fixel enhancement: Whole-brain statistical analysis of diffusion MRI measures in the presence of crossing fibres. NeuroImage, 117, 40-55. doi: 10.1016/j.neuroimage.2015.05.039
McCombe, P. A., Pfluger, C., Singh, P., Lim, C. Y. H., Airey, C. and Henderson, R. D. (2015). Serial measurements of phosphorylated neurofilament-heavy in the serum of subjects with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 353 (1-2), 122-129. doi: 10.1016/j.jns.2015.04.032
Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis
Simon, Neil G, Lee, Michael, Bae, Jong Seok, Mioshi, Eneida, Lin, Cindy S-Y, Pfluger, Casey M, Henderson, Robert D, Vucic, Steve, Swash, Michael, Burke, David and Kiernan, Matthew C (2015). Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis. Journal of Neurology, 262 (6), 1424-1432. doi: 10.1007/s00415-015-7721-8
Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis
Devine, Matthew S., Pannek, Kerstin, Coulthard, Alan, McCombe, Pamela A., Rose, Stephen E. and Henderson, Robert D. (2015). Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis. NeuroImage: Clinical, 7, 782-787. doi: 10.1016/j.nicl.2015.03.006
Devine, Matthew S., Kiernan, Matthew C., Heggie, Susan, McCombe, Pamela A. and Henderson, Robert D. (2014). Study of motor asymmetry in ALS indicates an effect of limb dominance on onset and spread of weakness, and an important role for upper motor neurons. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 15 (7-8), 481-487. doi: 10.3109/21678421.2014.906617
Vertebrobasilar dissections: case series comparing patients with and without dissecting aneurysms
Badve, Monica S., Henderson, Robert D., O'Sullivan, John D., Wong, Andrew A., Mitchell, Ken, Coulthard, Alan and Read, Stephen J. (2014). Vertebrobasilar dissections: case series comparing patients with and without dissecting aneurysms. Journal of Clinical Neuroscience, 21 (11), 2028-2030. doi: 10.1016/j.jocn.2014.02.015
Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood
Mantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005
Telehealth for motor neurone disease
Henderson, Robert D., Hutchinson, Nicole, Douglas, James A. and Douglas, Carol (2014). Telehealth for motor neurone disease. Medical Journal of Australia, 201 (1), 31-31. doi: 10.5694/mja14.00170
The tibialis anterior response revisited
Lehn, Alexander C., Dionisio, Sasha, Airey, Caroline A., Brown, Helen, Blum, Stefan and Henderson, Robert (2014). The tibialis anterior response revisited. Journal of Neurology, 261 (7), 1340-1343. doi: 10.1007/s00415-014-7329-4
Marginal reversible jump Markov chain Monte Carlo with application to motor unit number estimation
Drovandi, Christopher C., Pettitt, Anthony N., Henderson, Robert D. and McCombe, Pamela A. (2014). Marginal reversible jump Markov chain Monte Carlo with application to motor unit number estimation. Computational Statistics and Data Analysis, 72, 128-146. doi: 10.1016/j.csda.2013.11.003
Liu, Jia, Yan, Jun, Greer, Judith M., Read, Stephen J., Henderson, Robert D., Rose, Stephen E., Coulthard, Alan and McCombe, Pamela A. (2014). Correlation of adrenomedullin gene expression in peripheral blood leukocytes with severity of ischemic stroke. International Journal of Neuroscience, 124 (4), 271-280. doi: 10.3109/00207454.2013.837462
Forrest, Kimberley, O'Rourke, Peter, McCombe, Pamela and Henderson, Robert (2014). Venous thromboembolism in amyotrophic lateral sclerosis: Should we consider routine prophylactic anticoagulation?. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16 (3-4), 280-281. doi: 10.3109/21678421.2014.984724
A developmental perspective on bulbar involvement in amyotrophic lateral sclerosis
Devine, Matthew S., Farrell, Anna, Woodhouse, Helen, McCombe, Pamela A. and Henderson, Robert D. (2013). A developmental perspective on bulbar involvement in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (7-8), 638-639. doi: 10.3109/21678421.2013.812663
Susac syndrome and multifocal motor neuropathy first manifesting in pregnancy
Ioannides, Zara A., Airey, Caroline, Fagermo, Narelle, Blum, Stefan, McCombe, Pamela A. and Henderson, Robert J. (2013). Susac syndrome and multifocal motor neuropathy first manifesting in pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology, 53 (3), 314-317. doi: 10.1111/ajo.12069
Devine, Matthew S., Woodhouse, Helen, McCombe, Pam A. and Henderson, Robert D. (2013). The relationship between limb dominance, disease lateralization and spread of weakness in amyotrophic lateral sclerosis (ALS). Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (2), 150-151. doi: 10.3109/17482968.2012.725416
Nguyen, Giang Truong, Coulthard, Alan, Wong, Andrew, Sheikh, Nabeel, Henderson, Robert, O'Sullivan, John D. and Reutens, David C. (2013). Measurement of blood-brain barrier permeability in acute ischemic stroke using standard first-pass perfusion CT data. NeuroImage: Clinical, 2 (1), 658-662. doi: 10.1016/j.nicl.2013.04.004
Progressive brainstem deficits in an immunosuppressed patient
Chapman, P., Airey, C. and Henderson, R. D. (2013). Progressive brainstem deficits in an immunosuppressed patient. Journal of Clinical Neuroscience, 20 (1), 140-140. doi: 10.1016/j.jocn.2012.02.045
Use of Bayesian MUNE to show differing rate of loss of motor units in subgroups of ALS
Baumann, F., Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, Pamela A. (2012). Use of Bayesian MUNE to show differing rate of loss of motor units in subgroups of ALS. Clinical Neurophysiology, 123 (12), 2446-2453. doi: 10.1016/j.clinph.2012.04.022
Baumann, F., Henderson, R. D., Ridall, P. Gareth, Pettitt, A. N. and McCombe, Pamela A. (2012). Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset. Clinical Neurophysiology, 123 (10), 2092-2098. doi: 10.1016/j.clinph.2012.03.007
Ngo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028
Lin, C. Y., Pfluger, C. M., Henderson, R. D. and McCombe, P. A. (2012). Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis. Journal of Neuroimmunology, 249 (1-2), 93-95. doi: 10.1016/j.jneuroim.2012.05.001
Structural hemispheric asymmetries in the human precentral gyrus hand representation
Rose, S., Rowland, T., Pannek, K., Baumann, F., Coulthard, A., McCombe, P. and Henderson, R. (2012). Structural hemispheric asymmetries in the human precentral gyrus hand representation. Neuroscience, 210, 211-221. doi: 10.1016/j.neuroscience.2012.02.044
Optimal stimulation settings for CMAP scan registrations
Maathuis, Ellen M., Henderson, Robert D., Drenthen, Judith, Hutchinson, Nicole M., Daube, Jasper R., Blok, Joleen H. and Visser, Gerhard H. (2012). Optimal stimulation settings for CMAP scan registrations. Journal of Brachial Plexus and Peripheral Nerve Injury, 7, 4.1-4.7. doi: 10.1186/1749-7221-7-4
Frequency and function of regulatory T cells after ischaemic stroke in humans
Yan, Jun, Read, Stephen J., Henderson, Robert D., Hull, Renee, O'Sullivan, John D., McCombe, Pamela A. and Greer, Judith M. (2012). Frequency and function of regulatory T cells after ischaemic stroke in humans. Journal of Neuroimmunology, 243 (1-2), 89-94. doi: 10.1016/j.jneuroim.2011.12.019
Raffelt, David, Tournier, J.-Donald, Rose, Stephen, Ridgway, Gerard R., Henderson, Robert, Crozier, Stuart, Salvado, Olivier and Connelly, Alan (2012). Apparent fibre density: A novel measure for the analysis of diffusion-weighted magnetic resonance images. NeuroImage, 59 (4), 3976-3994. doi: 10.1016/j.neuroimage.2011.10.045
Rose, Stephen, Pannek, Kerstin, Bell, Christopher, Baumann, Fusun, Hutchinson, Nicole, Coulthard, Alan, McCombe, Pamela and Henderson, Robert (2012). Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study. NeuroImage, 59 (3), 2661-2669. doi: 10.1016/j.neuroimage.2011.08.054
Ischemic stroke and transient ischemic attack after head and neck radiotherapy: a review
Plummer, Chris, Henderson, Robert D., O'Sullivan, John D. and Read, Stephen J. (2011). Ischemic stroke and transient ischemic attack after head and neck radiotherapy: a review. Stroke, 42 (9), 2410-2418. doi: 10.1161/STROKEAHA.111.615203
Rowland, Tennille Jane, Turpin, Merrill, Gustafsson, Louise, Henderson, Robert David and Read, Stephen James (2011). Chedoke Arm and Hand Activity Inventory-9 (CAHAI-9): Perceived clinical utility within 14 days of stroke. Topics in Stroke Rehabilitation, 18 (4), 382-393. doi: 10.1310/tsr1804-382
Use and monitoring of low dose rituximab in myasthenia gravis
Blum, Stefan, Gillis, David, Brown, Helen, Boyle, Richard, Henderson, Robert, Heyworth-Smith, David, Hogan, Patrick, Kubler, Paul, Lander, Cecilie, Limberg, Nicole, Pillans, Peter, Prain, Kerri, Staples, Christopher, Walsh, Michael, McCombe, Pamela and Wong, Richard (2011). Use and monitoring of low dose rituximab in myasthenia gravis. Journal of Neurology, Neurosurgery and Psychiatry, 82 (6), 659-663. doi: 10.1136/jnnp.2010.220475
Rowland, Tennille, Gustafsson, Louise, Turpin, Merrill, Henderson, Robert and Read, Stephen (2011). Chedoke Arm and Hand Activity Inventory-9 (CAHAI-9): a multi-centre investigation of clinical utility. International Journal of Therapy and Rehabilitation, 18 (5), 290-297. doi: 10.12968/ijtr.2011.18.5.290
Singh, P., Yan, J., Hull, R., Read, S., O'Sullivan, J., Henderson, R.D., Rose, S., Greer, J.M. and McCombe, P.A. (2011). Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. Journal of the Neurological Sciences, 304 (1-2), 117-121. doi: 10.1016/j.jns.2011.01.025
The role of immune and inflammatory mechanisms in ALS
McCombe, P. A. and Henderson, R. D. (2011). The role of immune and inflammatory mechanisms in ALS. Current Molecular Medicine, 11 (3), 246-254. doi: 10.2174/156652411795243450
Atypical clinical presentations of the A3243G mutation, usually associated with MELAS
Blum, S., Robertson, T., Klingberg, S., Henderson, R.D. and McCombe, P. (2011). Atypical clinical presentations of the A3243G mutation, usually associated with MELAS. Internal Medicine Journal, 41 (2), 200-202. doi: 10.1111/j.1445-5994.2010.02379.x
Effects of gender in amyotrophic lateral sclerosis
McCombe, PA and Henderson, RD (2010). Effects of gender in amyotrophic lateral sclerosis. Gender Medicine, 7 (6), 557-570. doi: 10.1016/j.genm.2010.11.010
Biomarkers of disease in a case of familial lower motor neuron ALS
Baumann, Fusun, Rose, Stephen E., Nicholson, Garth A., Hutchinson, Nicole, Pannek, Kerstin, Pettitt, Anthony, McCombe, Pamela A. and Henderson, Robert D. (2010). Biomarkers of disease in a case of familial lower motor neuron ALS. Amyotrophic Lateral Sclerosis, 11 (5), 486-489. doi: 10.3109/17482961003774428
Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves
Baumann, Fusun, Henderson, Robert D., Tremayne, Fred, Hutchinson, Nicole and McCombe, Pamela A. (2010). Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves. Muscle & Nerve, 41 (6), 785-793. doi: 10.1002/mus.21604
The effect of ageing on human lymphocyte subsets: comparison of males and females
Yan, Jun, Greer, Judith M., Hull, Renee, O'Sullivan, John D., Henderson, Robert D., Read, Stephen J. and McCombe, Pamela A. (2010). The effect of ageing on human lymphocyte subsets: comparison of males and females. Immunity & Ageing, 7 (4) 1742, 1-10. doi: 10.1186/1742-4933-7-4
Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis
Baumann, Fusan, Henderson, Robert D., Morrison, Stephen C., Brown, Michael, Hutchinson, N., Douglas, James A., Robinson, Peter J. and McCombe, Pamela A. (2010). Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis, 11 (1-2), 194-202. doi: 10.3109/17482960902991773
Chapter 4 Bayesian analysis of the stimulus-response curve
Ridall, P. G., Pettitt, A. N., McCombe, P. A. and Henderson, R. D. (2009). Chapter 4 Bayesian analysis of the stimulus-response curve. Supplements to Clinical Neurophysiology, 60 (C), 47-56. doi: 10.1016/S1567-424X(08)00004-4
Chapter 5 Results of Bayesian statistical analysis in normal and ALS subjects
Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, P. A. (2009). Chapter 5 Results of Bayesian statistical analysis in normal and ALS subjects. Supplements to Clinical Neurophysiology, 60 (C), 57-63. doi: 10.1016/S1567-424X(08)00005-6
Henderson, Robert, Baumann, Fusun, Hutchinson, Nicole and McCombe, Pamela A. (2009). CMAP decrement in ALS. Muscle and Nerve, 39 (4), 555-556. doi: 10.1002/mus.21105
Immune activation in the peripheral blood of patients with acute ischemic stroke
Yan, Jun, Greer, Judith M., Etherington, Kellie, Cadigan, Greg P., Cavanagh, Helen, Henderson, Robert D., O'Sullivan, John D., Pandian, Jeyaraj D., Read, Stephen J. and McCombe, Pamela A. (2009). Immune activation in the peripheral blood of patients with acute ischemic stroke. Journal of Neuroimmunology, 206 (1-2), 112-117. doi: 10.1016/j.jneuroim.2008.11.001
Review of upper limb ability assessments in acute stroke care, from a practice perspective
Rowland, T. J., Gustafsson, L., Henderson, R. D., Turpin, M. and Read, S. J. (2009). Review of upper limb ability assessments in acute stroke care, from a practice perspective. International Journal of Therapy and Rehabilitation, 16 (12), 678-684. doi: 10.12968/ijtr.2009.16.12.45434
Kron, John, Henderson, Robert and Lombard, Jay (2008). Peripheral neuropathy. Journal of Complementary Medicine, 7 (6), 18-21.
Mollaret's meningitis and pituitary failure associated with a Rathke's cleft cyst
Dancer, C. M., Woods, M. L., Henderson, R. D., Robertson, T., Mungomery, M. and Allworth, A. (2008). Mollaret's meningitis and pituitary failure associated with a Rathke's cleft cyst. Internal Medicine Journal, 38 (7), 609-611. doi: 10.1111/j.1445-5994.2008.01709.x
Henderson, Robert (2008). Peripheral neuropathy. Australian Doctor (16), 33-38.
Images in Neuroscience: Restricted diffusion on MR imaging of an acute cerebral lesion
Pandian, Jeyaraj D., Rajah, Thulasi, Coulthard, Alan, Pender, Michael P. and Henderson, Robert D. (2008). Images in Neuroscience: Restricted diffusion on MR imaging of an acute cerebral lesion. Journal of Clinical Neuroscience, 15 (4), 456-487. doi: 10.1016/j.jocn.2007.02.007
Restricted diffusion on MR imaging of an acute cerebral lesion
Pandian, Jeyaraj D., Rajah, Thulasi, Coulthard, Alan, Pender, Michael P. and Henderson, Robert D. (2008). Restricted diffusion on MR imaging of an acute cerebral lesion. Journal of Clinical Neuroscience, 15 (4), 487-487. doi: 10.1016/j.jocn.2007.02.088
Natural history of blood glucose within the first 48 hours after ischemic stroke
Wong, A. A., Schluter, P. J., Henderson, R. D., O'Sullivan, J. D. and Read, S. J. (2008). Natural history of blood glucose within the first 48 hours after ischemic stroke. Neurology, 70 (13), 1036-1041. doi: 10.1212/01.wnl.0000306635.08410.68
The time course and determinants of blood pressure within the first 48 h after ischemic stroke
Wong, Andrew A., Davis, James P., Schluter, Philip J., Henderson, Robert D., O’Sullivan, John D. and Read, Stephen J. (2007). The time course and determinants of blood pressure within the first 48 h after ischemic stroke. Cerebrovascular Diseases, 24 (5), 426-433. doi: 10.1159/000108432
Pandian, Jeyaraj Durai, Perel, Robert, Henderson, Robert D., O'Sullivan, John D. and Read, Stephen (2007). Unusual triggers for stroke. Journal of Clinical Neuroscience, 14 (8), 786-787. doi: 10.1016/j.jocn.2006.05.012
Schoffer, Kerrie L., Henderson, Robert D., O'Maley, Karen and O'Sullivan, John D. (2007). Nonpharmacological treatment, fludrocortisone, and domperidone for orthostatic hypotension in Parkinson's disease. Movement Disorders, 22 (11), 1543-1549. doi: 10.1002/mds.21428
Bayesian statistical MUNE method
Henderson, R. D., Ridall, P. G., Hutchinson, N. M., Pettitt, A. N. and McCombe, P. A. (2007). Bayesian statistical MUNE method. Muscle & Nerve, 36 (2), 206-213. doi: 10.1002/mus.20805
Motor unit number estimation using reversible jump Markov chain Monte Carlo methods
Ridall, P. G., Pettitt, A. N., Friel, N., McCombe, P. A. and Henderson, R. D. (2007). Motor unit number estimation using reversible jump Markov chain Monte Carlo methods. Journal of the Royal Statistical Society, 56 (3), 235-269. doi: 10.1111/j.1467-9876.2007.00576.x
Postural orthostatic tachycardia syndrome: an underrecognized disorder
Pandian, J. D., Dalton, K., Henderson, R. D. and McCombe, P. A. (2007). Postural orthostatic tachycardia syndrome: an underrecognized disorder. Internal Medicine Journal, 37 (8), 529-535. doi: 10.1111/j.1445-5995.2007.01356.x
Rhizomycosis infection in the basal ganglia
Pandian, J. D., McCarthy, J. S., Goldschlager, T., Robertson, T. and Henderson, R. D. (2007). Rhizomycosis infection in the basal ganglia. Archives of Neurology, 64 (1), 134-135. doi: 10.1001/archneur.64.1.134
The time course and determinants of temperature within the first 48 h after ischaemic stroke
Wong, A. A., Davis, J. P., Schluter, P. J., Henderson, R. D., O'Sullivan, J. D. and Read, S. J. (2007). The time course and determinants of temperature within the first 48 h after ischaemic stroke. Cerebrovascular Diseases, 24 (1), 104-110. doi: 10.1159/000103124
Motor unit number estimation - A Bayesian approach
Ridall, P. Gareth, Pettitt, Anthony N., Henderson, Robert D. and McCombe, Pamela A. (2006). Motor unit number estimation - A Bayesian approach. Biometrics, 62 (4), 1235-1250. doi: 10.1111/j.1541-0420.2006.00577.x
Cerebral Vasculitis in Ulcerative Colitis
Pandian, Jeyaraj Durai, Henderson, Robert D., O'Sullivan, John D. and Rajah, Thulasi (2006). Cerebral Vasculitis in Ulcerative Colitis. Archives of Neurology, 63 (5), 780-780. doi: 10.1001/archneur.63.5.780
Establishment of an Australian motor neurone disease registry
Kiernan, M. C., Talman, P., Henderson, R. D. and Harris, R. (2006). Establishment of an Australian motor neurone disease registry. Medical Journal of Australia, 184 (7), 367-368. doi: 10.5694/j.1326-5377.2006.tb00279.x
Lower Motor Neuron Weakness After Diving-Related Decompression
Henderson, Robert D. and Pender, Michael P. (2006). Lower Motor Neuron Weakness After Diving-Related Decompression. Neurology, 66 (3), 451-452. doi: 10.1212/01.wnl.0000196484.92748.b2
Circadian blood pressure variation after acute stroke
Pandian, Jeyaraj D., Wong, Andrew A., Lincoln, Douglas J., Davis, James P., Henderson, Robert D., OSullivan, John D. and Read, Stephen J. (2006). Circadian blood pressure variation after acute stroke. Journal of Clinical Neuroscience, 13 (5), 558-562. doi: 10.1016/j.jocn.2005.09.003
Henderson, R. D., Ridall, G. R., Pettitt, A. N., McCombe, P. A. and Daube, J. R. (2006). The stimulus-response curve and motor unit variability in normal subjects and subjects with amyotrophic lateral sclerosis. Muscle & Nerve, 34 (1), 34-43. doi: 10.1002/mus.20561
'Boomerang sign' in the splenium of the corpus callosum
Pandian, J. D. and Henderson, R. D. (2005). 'Boomerang sign' in the splenium of the corpus callosum. Medical Journal of Australia, 183 (11/12), 628-628. doi: 10.5694/j.1326-5377.2005.tb00059.x
Case report: inspiratory muscle training in chronic critically ill patients - A report of two cases
Chang, Angela T., Boots, Robert J., Henderson, Robert D., Paratz, Jennifer D. and Hodges, Paul W. (2005). Case report: inspiratory muscle training in chronic critically ill patients - A report of two cases. Physiotherapy Research International, 10 (4), 222-226. doi: 10.1002/pri.14
Chronic inflammatory demyelinating polyneuropathy and respiratory failure
Henderson, R., Sandroni, P. and Wijdicks, E. F. M. (2005). Chronic inflammatory demyelinating polyneuropathy and respiratory failure. Journal of Neurology, 252 (10), 1235-1237. doi: 10.1007/s00415-005-0848-2
Riluzole: A glimmer of hope in the treatment of motor neurone disease
Henderson, R. D. and McCombe, P. A. (2005). Riluzole: A glimmer of hope in the treatment of motor neurone disease. Medical Journal of Australia, 183 (3), 164-164.
Assessment of disease progression in motor neuron disease
Winhammar, Jennica M. C., Rowe, Dominic B., Henderson, Robert D. and Kiernan, Matthew C. (2005). Assessment of disease progression in motor neuron disease. Lancet Neurology, 4 (4), 229-238. doi: 10.1016/S1474-4422(05)70042-9
Cerebeller vermis hyperdensity on CT scan
Wolski, P., Read, S. J., O'Sullivan, J. D. and Henderson, R. D. (2005). Cerebeller vermis hyperdensity on CT scan. Journal of Clinical Neuroscience, 12 (6), 676-676. doi: 10.1016/j.jocn.2005.03.011
Schoffer, Kerrie L., Patterson, Victor, Read, Stephen J., Henderson, Robert D., Pandian, Jeyaraj D. and O'Sullivan, John D. (2005). Guidelines for filming digital camera video clips for the assessment of gait and movement disorders by teleneurology. Journal of Telemedicine and Telecare, 11 (7), 368-371. doi: 10.1258/135763305774472042
Ring enhancement after hemorrhagic stroke
Wong, A.A., Henderson, R. D., O'Sullivan, J. D., Read, S. J. and Rajah, R.T. (2005). Ring enhancement after hemorrhagic stroke. Archives of Neurology, 61 (11), 1790-1790. doi: 10.1001/archneur.61.11.1790
The effect of admission physiological variables on 30 day outcome after stroke
Wong, Andrew A., Davis, James P., Schluter, Philip J., Henderson, Robert D., O'Sullivan, John D. and Read, Stephen J. (2005). The effect of admission physiological variables on 30 day outcome after stroke. Journal of Clinical Neuroscience, 12 (8), 905-910. doi: 10.1016/j.jocn.2004.11.012
Impact of premorbid undernutrition on outcome in stroke patients
Davis, James P., Wong, Andrew A., Schluter, Philip J., Henderson, Robert D., OSullivan, John D. and Read, Stephen J. (2004). Impact of premorbid undernutrition on outcome in stroke patients. Stroke, 35 (8), 1930-1934. doi: 10.1161/01.STR.0000135227.10451.c9
Decrement in surface-recorded motor unit potentials in amyotrophic lateral sclerosis
Henderson, R. D. and Daube, J. R. (2004). Decrement in surface-recorded motor unit potentials in amyotrophic lateral sclerosis. Neurology, 63 (9), 1670-1674. doi: 10.1212/01.WNL.0000142534.78461.42
Henderson, R. D., Walker, D. G., Mitchell, K. and Read, S. J. (2004). More than one dilemma. Neurocritical Care, 1 (3), 375-378. doi: 10.1385/NCC:1:3:375
Adult onset Krabbe disease may mimic motor neurone disease
Henderson, R. D., MacMillan, J. C. and Bradfield, J. M. (2003). Adult onset Krabbe disease may mimic motor neurone disease. Journal of Clinical Neuroscience, 10 (5), 638-639. doi: 10.1016/S0967-5868(02)00302-8
Effect of changing data collection parameters on statistical motor unit number estimates
Henderson, R. D., McClelland, R. and Daube, J. R. (2003). Effect of changing data collection parameters on statistical motor unit number estimates. Muscle & Nerve, 27 (3), 320-331. doi: 10.1002/mus.10325
The morbidity of Guillain-Barré syndrome admitted to the intensive care unit
Henderson, R. D., Fletcher, D. D., McClelland, R. L. and Wijdicks, E. F. M. (2003). The morbidity of Guillain-Barré syndrome admitted to the intensive care unit. Neurology, 60 (1), 17-21.
Emergency intubation for respiratory failure in Guillain-Barre Syndrome
Wijdicks, Eelco F. M., Henderson, Robert D. and McClelland, Robyn L. (2003). Emergency intubation for respiratory failure in Guillain-Barre Syndrome. Archives of Neurology, 60 (7), 947-948. doi: 10.1001/archneur.60.7.947
Posterior leukoencephalopathy following, intrathecal chemotherapy with MRA-documented vasospasm
Henderson, RD, Rajah, T, Nicol, AJ and Read, SJ (2003). Posterior leukoencephalopathy following, intrathecal chemotherapy with MRA-documented vasospasm. Neurology, 60 (2), 326-328.
Progressive multifocal leukoencephalopathy
Henderson, R. D., Smith, M. G., Mowat, P. and Read, S. J. (2002). Progressive multifocal leukoencephalopathy. Neurology, 58 (12), 1825-1825.
Chuah, T. L., Tan, S. M., Flanagan, S., Hyland, V., Sullivan, A. A., Henderson, R., MacMillan, J. and Lander, C. (2001). CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy): an Australian perspective. Journal of Clinical Neuroscience, 8 (5), 404-406. doi: 10.1054/jocn.2000.0848
Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient
McLaughlin, DB, Eadie, MJ, Parker-Scott, SL, Addison, RS, Henderson, RD, Hooper, WD and Dickinson, RG (2000). Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient. Epilepsy Research, 41 (3), 259-268. doi: 10.1016/S0920-1211(00)00151-0
Henderson, R. D., Healy, H. G., McCombe, P. A. and Lander, C. M. (2000). Chronic inflammatory demyelinating polyradiculoneuropathy and severe peripheral oedema: a renal explanation. Journal of Clinical Neuroscience, 7 (2), 148-149. doi: 10.1054/jocn.1999.0170
Pender, Michael P., Csurhes, Peter A., Greer, Judith M., Mowat, Paul D., Henderson, Robert D., Cameron, Kaye D., Purdie, David M., McCombe, Pamela A. and Good, Michael F. (2000). Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis than in Healthy Subjects. Journal of Immunology, 165 (9), 5322-5331. doi: 10.4049/jimmunol.165.9.5322
The Occurrence of Autoimmune Diseases in Patients with Multiple Sclerosis and Their Families
Henderson, R. D., Bain, C. J. and Pender, M. P. (2000). The Occurrence of Autoimmune Diseases in Patients with Multiple Sclerosis and Their Families. Journal of Clinical Neuroscience, 7 (5), 434-437. doi: 10.1054/jocn.2000.0693
Living renal donor health eligibility: A European "best practice" protocol?
Donnelly, P. K., Henderson, R. and Price, D. (1999). Living renal donor health eligibility: A European "best practice" protocol?. Transplant proceedings, 31 (1-2), 1322-1323. doi: 10.1016/S0041-1345(98)02014-4
Goodpasture's Syndrome Associated with Multiple Sclerosis
Henderson, R. D., Saltissi, D. and Pender, M. P. (1998). Goodpasture's Syndrome Associated with Multiple Sclerosis. Acta Neurologica Scandinavica, 98 (2), 134-135. doi: 10.1111/j.1600-0404.1998.tb01733.x
Guillain-Barre Syndrome and Optic Neuritis after Mycoplasma Pneumoniae Infection
Henderson, R. D., Ohlrich, G. D. and Pender, M. P. (1998). Guillain-Barre Syndrome and Optic Neuritis after Mycoplasma Pneumoniae Infection. Australian and New Zealand Journal of Medicine, 28 (4), 481-482. doi: 10.1111/j.1445-5994.1998.tb02093.x
Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T
Chang, Jeryn, Steyn, Frederik, Ngo, Shyuan, Henderson, Robert, Guo, Christine, Bollmann, Steffen, Fripp, Jurgen, Barth, Markus and Shaw, Thomas (2023). Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T. Concord, CA: ISMRM. doi: 10.58530/2022/3808
Low dose Rituximab in the treatment of myasthenia gravis
Chan, Fiona, Swayne, Andrew, Gillis, David, Wong, Richard, Walsh, Michael, Henderson, Robert, McCombe, Pamela and Blum, Stefan (2020). Low dose Rituximab in the treatment of myasthenia gravis. 18th Biennial Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Gold Coast, QLD, Australia, 29 September–2 October 2019. E Park, Shannon, Ireland: Elsevier . doi: 10.1016/j.clinph.2019.11.034
Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants
Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81
Xu, Zhouwei, Lee, Aven, Henderson, Robert and McCombe, Pamela (2017). Gelsolin, clusterin and Cd5L are the potential plasma biomarkers of amyotrophic lateral sclerosis with and without cognitive impairment. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.34
Ioannides, Zara A., Ngo, Shyuan T., Henderson, Robert D., McCombe, Pamela A. and Steyn, Frederik J. (2017). Hypermetabolism in Motor Neurone Disease Is Associated with a Greater Functional Decline But Not Weight Loss. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.18
Xu, Zhouwei, Alruwaili, Ashwag, Henderson, Robert and McCombe, Pamela (2017). Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, QLD, Australia, 9-12 May 2017. London, United Kingdom: BMJ Group. doi: 10.1136/jnnp-2017-316074.29
Ioannides, Zara A., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2017). The risk of overestimating fatness in motor neurone disease: longitudinal assessments of body composition. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.35
Peripheral immune complement activation in neurodegenerative disease
Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188
Relationship between subacute brain activity and aphasia recovery
Roxbury, T., McMahon, K., Read, S., Henderson, R., Wong, A., Coulthard, A., Farrell, A., Burfein, P., Taubert, S., Buckley, R., McHenery, C. and Copland, D. (2014). Relationship between subacute brain activity and aphasia recovery. 15th International Science of Aphasia Conference, Venice, Italy, 19-24 September 2014. Utrecht, The Netherlands: Swets and Zeitlinger BV.
Using fMRI to predict post-stroke aphasia recovery
Copland, D. A., Roxbury, T., McMahon, K., Read, S., Henderson, R., Wong, A., Coulthard, A., Farrell, A., Burfein, P., Taubert, S., Buckley, R. and McHenery, C. (2014). Using fMRI to predict post-stroke aphasia recovery. International Stroke Conference 2014, San Diego, CA, United States, 12-14 February 2014. London, United Kingdom: Sage Publications. doi: 10.1111/ijs.12297
A drop in the average age of stroke patients
Anderlini, D., Wallis, G., Henderson, R. and Wong, A. (2013). A drop in the average age of stroke patients. 24th Annual Scientific Meeting of the Stroke Society of Australia, Darwin, NT, Australia, 31 July-2 August 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ijs.12143
CT perfusion and bilateral paramedian thalamic stroke due to Artery of Percheron occlusion
Sheikh, N., Wong, A., O'Sullivan, J., Blum, S., Airey, C., Dionisio, S., Mitchell, K., Coulthard, A., Cloustan, J., Groundwater, A., Rajah, T., Jhamb, A. and Henderson, R. (2012). CT perfusion and bilateral paramedian thalamic stroke due to Artery of Percheron occlusion. Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney, NSW, Australia, 29-31 August 2012. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1747-4930.2012.00907.x
Bayesian Statistical Motor Unit Number Estimation in the Assessment of ALS
McCombe, Pamela A., Baumann, Fusun, Henderson, Robert and Anthony, Pettitt (2011). Bayesian Statistical Motor Unit Number Estimation in the Assessment of ALS. 63rd Annual Meeting of the American-Academy-of-Neurology, Honolulu, HI, U.S.A., APR 09-16, 2011. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins.
McCombe, P., Ngo, S., Bellingham, M., Pettitt, A. and Henderson, R. (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd AAN Annual Meeting, Honolulu, HI, United States, 9-16 April 2011.
McCombe, Pamela, Ngo, Shuyan, Bellingham, Mark, Pettitt, Anthony and Henderson, Robert (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd Annual Meeting of the American-Academy-of-Neurology, Honolulu, HI, U.S.A., APR 09-16, 2011. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins.
Ngo, S. T., Bellingham, M. C., Pettitt, A. N., Ridall, P. G., Henderson, R. D. and McCombe, P. A. (2011). Comparison of motor unit number estimation by Bayesian statistical MUNE with histological counting of motor unit numbers. 22nd International ALS/MND Symposium, Sydney, Australia, 30 November - 2 December 2011.
Estimation of Motor Unit Loss in Amyotrophic Lateral Sclerosis (ALS)
Ngo, S. T., Baumann, F., Pettitt, A. N., Ridall, P. G., Henderson, R. D., McCombe, P. A. and Bellingham, M. C. (2011). Estimation of Motor Unit Loss in Amyotrophic Lateral Sclerosis (ALS). Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand, 31 January -3 February 2011.
Bayesian Motor Unit Number Estimation in the SOD1G93A mouse
Ngo, S.T., Bellingham, M.C., Baumann, F., Pettitt, A.N., Ridall, P.G., Henderson, R.D. and McCombe, P.A. (2010). Bayesian Motor Unit Number Estimation in the SOD1G93A mouse. Forum of European Neuroscience, AMSTERDAM NETHERLANDS, 3/7/2010-7/7/2010.
Clinical features of patients with demyelinating neuropathy associated with Anti-MAG antibody
Kleinschmidt, Grant D., Henderson, Robert D. and McCombe, Pamela (2010). Clinical features of patients with demyelinating neuropathy associated with Anti-MAG antibody. ANZAN Annual Scientific Meeting 2010, -, 2010. Elsevier. doi: 10.1016/j.jocn.2010.07.081
Immune response in acute ischaemic stroke
Badve, Monica S., Yan, J., Hull, R., Henderson, Robert, O’Sullivan, John D., Read, Stephen J., Wong, Andrew A. and McCombe, Pamela (2010). Immune response in acute ischaemic stroke. ANZAN Annual Scientific Meeting 2010, -, 2010. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jocn.2010.07.064
The FA connectome: A quantitative strategy for studying neurological disease processes
Rose, Stephen, Pannek, Kerstin, Salvado, Oliver, Raniga, Parnesh, Baumann, Fusun and Henderson, Robert (2010). The FA connectome: A quantitative strategy for studying neurological disease processes. 18th International Society of Magnetic Resonance in Medicine (ISMRM) Scientific Meeting, Stockholm, Sweden, 1-7 May 2010.
Unusual clinical presentations associated with the A3243G mutation
Blum, Stefan, Robertson, Thomas, Klingberg, Sandra, Henderson, Robert and McCombe, Pamela (2010). Unusual clinical presentations associated with the A3243G mutation. ANZAN Annual Scientific Meeting 2010, -, 2010. Elsevier. doi: 10.1016/j.jocn.2010.07.066
Bayesian analysis of the stimulus-response curve
Ridall, P. G., Pettitt, A. N., McCombe, P. A. and Henderson, R. D. (2009). Bayesian analysis of the stimulus-response curve. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00004-4
McCombe, P. A., Henderson, R. D., Ridall, P. G. and Pettitt, A. N. (2009). Biological basis for motor unit number estimation through Bayesian statistical analysis of the stimulus-response curve. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00003-2
Results of Bayesian statistical analysis in normal and ALS subjects
Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, P. A. (2009). Results of Bayesian statistical analysis in normal and ALS subjects. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00005-6
Increased population of activated T cells in patients after acute ischemic stroke
Yan, J., Greer, J. M., Cavanagh, H., Henderson, R., O'Sullivan, J., Read, S., Etherington, K. and McCombe, P. A. (2007). Increased population of activated T cells in patients after acute ischemic stroke. 37th Annual Scientific Meeting of the Australasian Society for Immunology, Sydney, Australia, 2-6 December 2007.
Quantitative EEG may inform sub-acute stroke prognoses
Finnigan, Simon, Pandian, Jeyaraj D., Henderson, Robert, Rose, Stephen E. and Chalk, Jonathan B. (2007). Quantitative EEG may inform sub-acute stroke prognoses. Stroke Society of Australasia Annual Scientific Meeting 2006, Adelaide, SA, Australia, 11-13 October 2006. Carlton, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2007.01308.x
Circadian blood pressure variation after acute stroke
Pandian, J., Wong, A., Lincoln, D., Davis, J., Henderson, R., O'Sullivan, J. and Read, S. (2005). Circadian blood pressure variation after acute stroke. 18th World Congress of Neurology, Sydney, Australia, 5-11 November 2005. Amsterdam, Netherlands: Elsevier .
Pender, M. P., Csurhes, P. A., Greer, J. M., Mowat, P. D., Henderson, R. D., Cameron, K. D., McCombe, P. A. and Good, M. F. (1999). Fluctuations in the frequencies of circulating myelin-reactive T cells in healthy subjects and patients with multiple sclerosis. ECTRIMS/ACTRIMS'99, Basel, Switzerland, 15 - 18 Sept, 1999. Basingstoke, England: Stockton Press.
Cameron, K. D., Csurhes, P. A., Good, M. F., Greer, J. M., Henderson, R. D., McCombe, P. A., Mowat, P. D. and Pender, M. P. (1998). The frequency of circulating T cells reactive to PLP184-209 increases prior to MS relapse and development of new MR1 lesions. Fifth International Congress of the International Society of Neuroimmunology, Montreal, QC, Canada, 23-27 August 1998. doi: 10.1016/S0165-5728(98)91636-8
Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls
Anna Freydenzon, Allan F. McRaee, Shyuan Ngo, Naomi R. Wray, Leanne Wallace, Anjali K. Henders, Pamela A. McCombe, Robert D. Henderson and Frederik J. Steyn (2023). Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls. The University of Queensland. (Dataset) doi: 10.48610/b722f1f
Examination of surface-recorded motor units and a new approach to motor unit number estimates
Henderson, Robert David (2007). Examination of surface-recorded motor units and a new approach to motor unit number estimates. PhD Thesis, School of Medicine, University of Queensland.
(2023–2024) Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
(2022) Motor Neurone Disease Research Institute of Australia Inc Linda Rynalski Bridge Funding Grant
(2021–2023) Motor Neurone Disease Research Institute of Australia Inc
N-acetyltransferase 1, a modifier of disease outcome in patients with Motor Neurone Disease (MND).
(2021–2022) Metro North Hospital and Health Service
Targeting NAT1 to improve metabolism and slow disease progression in MND
(2021–2022) Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
(2020–2022) Royal Brisbane and Women's Hospital
(2020–2022) Motor Neurone Disease Research Institute of Australia Inc
(2020–2021) Metro North Hospital and Health Service
Immunogenetics of motor neurone disease - a pilot study
(2019–2020) Motor Neurone Disease Research Institute of Australia Inc
(2018–2023) University of Sydney
A novel ephrin receptor A4-Fc fusion protein for the treatment of motor neuron disease
(2018–2021) Cure for MND Foundation - Translational Research Grants
Use of mass spectrometry to identify circulating toxins in the people with ALS
(2018–2020) Wesley Merdical Research
Investigating the proteome of MND brains
(2018–2019) Metro North Hospital and Health Service
(2018–2019) Motor Neurone Disease Research Institute of Australia Inc
Novel biomarkers for motor neurone disease
(2018–2019) Motor Neurone Disease Research Institute of Australia Inc
(2018–2019) Metro North Hospital and Health Service
(2017–2019) Wesley Medical Research Ltd
(2017–2018) Motor Neurone Disease Research Institute of Australia Inc
Discovery of EAAT5 - a protein that may stop glutamate excitotoxicity in ALS
(2017) Motor Neurone Disease Research Institute of Australia Inc
Metabolic and gut dynamics in MND: Identifying novel strategies to meet energy needs in patients
(2016) Motor Neurone Disease Research Institute of Australia Inc
Using biomarkers to explore heterogeneity of motor neurone disease
(2016) Motor Neurone Disease Research Institute of Australia Inc
(2015) Motor Neurone Disease Research Institute of Australia Inc
(2015) Motor Neurone Disease Research Institute of Australia Inc
Mass spectrometry to search for biomarkers in motor neurone disease
(2015) Royal Brisbane and Women's Hospital
(2015) Royal Brisbane and Women's Hospital Foundation
(2015) Royal Brisbane and Women's Hospital Foundation
The role of altered neuromuscular signaling in ALS: factors that modify the course of MND
(2014–2015) Motor Neurone Disease Research Institute of Australia Inc
Whole exome sequencing of sporadic MND
(2014–2015) Motor Neurone Disease Research Institute of Australia Inc
Targeting EphA4 as a treatment for MND
(2014) Motor Neurone Disease Research Institute of Australia Inc
Biomarkers of disease progression in MND
(2013–2014) UQ Academic Title Holder Research Fund
Use of biomarkers to understand Amyotrophic Lateral Sclerosis
(2013) Motor Neurone Disease Research Institute of Australia Inc
Using biomarkers to assess disease progression and understanding of MND
(2013) Royal Brisbane and Women's Hospital
Blood Biomarkers in Motor Neurone Disease
(2012–2013) Royal Brisbane and Women's Hospital
(2012) Motor Neurone Disease Research Institute of Australia Inc
Nature and timing of inflammation after acute ischaemic stroke
(2011–2013) National Heart Foundation of Australia
(2011) Motor Neurone Disease Research Institute of Australia Inc
Development of a new method of motor unit number estimation for use in motor neurone disease
(2009–2012) NHMRC Project Grant
Identifying biomarkers for MND using flow cytometry.
(2009–2010) Motor Neurone Disease Research Institute of Australia Inc
(2008–2011) NHMRC Project Grant
Supplementary funding to advance development
(2005–2006) Royal Brisbane & Women's Hospital Research Foundation
Motor Unit Analysis in Motor Neurone Disease
(2002–2004) Motor Neurone Disease Association Queensland Inc
Use of bioinformatics to decode disease heterogeneity in motor neuron disease
Doctor Philosophy — Associate Advisor
Other advisors:
Survival and heterogeneity in Motor Neurone Disease
Doctor Philosophy — Associate Advisor
Other advisors:
Targeting metabolic flexibility as a therapeutic approach for ALS (METALS)
Doctor Philosophy — Associate Advisor
Other advisors:
Asymmetry and Vulnerability in Amyotrophic Lateral Sclerosis
(2019) Doctor Philosophy — Principal Advisor
Other advisors:
Studies of Amyotrophic Lateral Sclerosis
(2022) Master Philosophy — Associate Advisor
Other advisors:
Clinical and laboratory features of ALS
(2018) Doctor Philosophy — Associate Advisor
Other advisors:
(2017) Master Philosophy — Associate Advisor
Other advisors:
(2017) Doctor Philosophy — Associate Advisor
Other advisors:
Biomarkers of Motor Neurone Disease : Neurophysiological studies of lower motor degeneration
(2012) Doctor Philosophy — Associate Advisor
Other advisors: