The University of Queensland

Isolation and Culture Techniques for Fetal Mouse Germ Cells

Burnet, Guillaume, Bowles, Josephine and Spiller, Cassy M. (2023). Isolation and Culture Techniques for Fetal Mouse Germ Cells. Methods in Molecular Biology. (pp. 221-231) New York, NY: Springer US. doi: 10.1007/978-1-0716-3259-8_13

Sexually dimorphic germ cell identity in mammals

Spiller, Cassy and Bowles, Josephine (2019). Sexually dimorphic germ cell identity in mammals. Sex determination in vertebrates. (pp. 253-288) Maryland Heights, MO, United States: Academic Press. doi: 10.1016/bs.ctdb.2019.01.011

Mouse fetal germ cell isolation and culture techniques

Spiller, Cassy M., Burnet, Guillaume and Bowles, Josephine (2017). Mouse fetal germ cell isolation and culture techniques. Germline stem cells. (pp. 173-183) edited by Michael Buszczak. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-4017-2_13

Retinoic acid and the control of meiotic initiation

Bowles, Josephine and Koopman, Peter (2015). Retinoic acid and the control of meiotic initiation. The retinoids: biology, biochemistry, and disease. (pp. 383-399) edited by Pascal Dolle and Karen Niederreither. New Jersey, NY, United States: Wiley - Blackwell. doi: 10.1002/9781118628003.ch17

In situ hybridization of whole-mount embryos

Hargrave, M. R., Bowles, J. and Koopman, P A (2006). In situ hybridization of whole-mount embryos. In Situ Hybridization Protocols 3rd ed. (Methods in Molecular Biology, Vol. 326). (pp. 103-114) edited by Darby, I. and Hewitson, T.. Totowa, New Jersey, USA 07512: Humana Press.

Gonads-Mullerian Ducts

Bowles, J. and Koopman, P. A. (2004). Gonads-Mullerian Ducts. Handbook of Stem Cells Volume 1. (pp. 345-357) edited by Lanza, R.P.; Gearhart, B.L.M.; Melton, D.A.;Pederson, R.; Thomson, M.D.; West and M.D.. USA: Elsevier Academic Oress. doi: 10.1016/B978-012436643-5/50042-0

Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

Ayers, Katie L., Eggers, Stefanie, Rollo, Ben N., Smith, Katherine R., Davidson, Nadia M., Siddall, Nicole A., Zhao, Liang, Bowles, Josephine, Weiss, Karin, Zanni, Ginevra, Burglen, Lydie, Ben-Shachar, Shay, Rosensaft, Jenny, Raas-Rothschild, Annick, Jørgensen, Anne, Schittenhelm, Ralf B., Huang, Cheng, Robevska, Gorjana, van den Bergen, Jocelyn, Casagranda, Franca, Cyza, Justyna, Pachernegg, Svenja, Wright, David K., Bahlo, Melanie, Oshlack, Alicia, O’Brien, Terrence J., Kwan, Patrick, Koopman, Peter, Hime, Gary R. ... Sinclair, Andrew H. (2023). Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects. Nature Communications, 14 (1) 3403, 1-21. doi: 10.1038/s41467-023-39040-0

Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization

Burnet, Guillaume, Feng, Chun‐Wei Allen, Cheung, Ka Man Fiona, Bowles, Josephine and Spiller, Cassy M. (2023). Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization. genesis, 61 (1-2) e23511, e23511. doi: 10.1002/dvg.23511

Instructing mouse germ cells to adopt a female fate

Spiller, Cassy and Bowles, Josephine (2022). Instructing mouse germ cells to adopt a female fate. Sexual Development, 16 (5-6), 1-13. doi: 10.1159/000523763

Deletion of NFIX results in defective progression through meiosis within the mouse testis

Davila, Raul Ayala, Spiller, Cassy, Harkins, Danyon, Harvey, Tracey, Jordan, Philip W., Gronostajski, Richard M., Piper, Michael and Bowles, Josephine (2022). Deletion of NFIX results in defective progression through meiosis within the mouse testis. Biology of Reproduction, 106 (6), 1191-1205. doi: 10.1093/biolre/ioac049

Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency

Nakagawa, Ryuichi, Takasawa, Kei, Gau, Maki, Tsuji-Hosokawa, Atsumi, Kawaji, Hideya, Murakawa, Yasuhiro, Takada, Shuji, Mikami, Masashi, Narumi, Satoshi, Fukami, Maki, Sreenivasan, Rajini, Maruyama, Tetsuo, Tucker, Elena J., Zhao, Liang, Bowles, Josephine, Sinclair, Andrew, Koopman, Peter, Hayashizaki, Yoshihide, Morio, Tomohiro and Kashimada, Kenichi (2022). Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency. Human Molecular Genetics, 31 (13), 2223-2235. doi: 10.1093/hmg/ddac023

AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

Kam Draskau, Monica, Ravn Ballegaard, Anne-Sofie, Ramhøj, Louise, Bowles, Josephine, Svingen, Terje and Spiller, Cassy M. (2022). AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes. Current Research in Toxicology, 3 100069, 1-8. doi: 10.1016/j.crtox.2022.100069

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5

Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse

Feng, Chun-Wei, Burnet, Guillaume, Spiller, Cassy M., Cheung, Fiona Ka Man, Chawengsaksophak, Kallayanee, Koopman, Peter and Bowles, Josephine (2021). Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse. Development, 148 (5) dev194977, 1-13. doi: 10.1242/dev.194977

CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males

Spiller, Cassy M., Lobo, João, Boellaard, Willem P. A., Gillis, Ad J. M., Bowles, Josephine and Looijenga, Leendert H. J. (2020). CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males. Cancers, 12 (3) 760, 760. doi: 10.3390/cancers12030760

Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways

Draskau, Monica Kam, Spiller, Cassy M., Boberg, Julie, Bowles, Josephine and Svingen, Terje (2020). Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways. Molecular Human Reproduction, 26 (2), 111-116. doi: 10.1093/molehr/gaaa001

A simple, web-based repository for the management, access and analysis of micrographic images

Davila, Raul Ayala, Harkins, Danyon, Currey, Laura, Fraser, James, Bowles, Josephine and Piper, Michael (2019). A simple, web-based repository for the management, access and analysis of micrographic images. Journal of Molecular Histology, 50 (6), 573-580. doi: 10.1007/s10735-019-09850-y

Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacqueline, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2019). Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 10 (1) 3351, 3351. doi: 10.1038/s41467-019-11310-w

Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling

Nomura, Risa, Kashimada, Kenichi, Suzuki, Hitomi, Zhao, Liang, Tsuji-Hosokawa, Atsumi, Yagita, Hideo, Takagi, Masatoshi, Kanai, Yoshiakira, Bowles, Josephine, Koopman, Peter, Kanai-Azuma, Masami and Morio, Tomohiro (2019). Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling. Journal of Cell Science, 132 (8) 223768, jcs223768. doi: 10.1242/jcs.223768

Gene editing of the multi-copy H2A.B gene and its importance for fertility 06 Biological Sciences 0604 Genetics Jin-Soo Kim

Anuar, Nur Diana, Kurscheid, Sebastian, Field, Matt, Zhang, Lei, Rebar, Edward, Gregory, Philip, Buchou, Thierry, Bowles, Josephine, Koopman, Peter, Tremethick, David J. and Soboleva, Tatiana A. (2019). Gene editing of the multi-copy H2A.B gene and its importance for fertility 06 Biological Sciences 0604 Genetics Jin-Soo Kim. Genome Biology, 20 (1) 23, 23. doi: 10.1186/s13059-019-1633-3

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacky, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2018). Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 9 (1) 5319, 5319. doi: 10.1038/s41467-018-07784-9

Retinoic acid antagonizes testis development in mice

Bowles, Josephine, Feng, Chun-Wei, Ineson, Jessica, Miles, Kim, Spiller, Cassy M., Harley, Vincent R., Sinclair, Andrew H. and Koopman, Peter (2018). Retinoic acid antagonizes testis development in mice. Cell Reports, 24 (5), 1330-1341. doi: 10.1016/j.celrep.2018.06.111

Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring

Walton, Sarah L., Singh, Reetu R., Little, Melissa H., Bowles, Josephine, Li, Joan and Moritz, Karen M. (2018). Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring. The Journal of Physiology, 596 (23), 5873-5889. doi: 10.1113/JP275918

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling

Sinha, Debottam, Kalimutho, Murugan, Bowles, Josephine, Chan, Ai-Leen, Merriner, D. Jo, Bain, Amanda L., Simmons, Jacinta L., Freire, Raimundo, Lopez, J Alejandro, Hobbs, Robin M., O'Bryan, Moira K. and Khanna, Kum Kum (2018). Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. The FASEB Journal, 32 (9), 4984-4999. doi: 10.1096/fj.201701096RR

SOX30 is required for male fertility in mice

Feng, Chun-Wei Allen, Spiller, Cassy, Merriner, Donna J., O'Bryan, Moira K., Bowles, Josephine and Koopman, Peter (2017). SOX30 is required for male fertility in mice. Scientific Reports, 7 (1) 17619, 1-12. doi: 10.1038/s41598-017-17854-5

Sex Determination in the Mammalian Germline

Spiller, Cassy, Koopman, Peter and Bowles, Josephine (2017). Sex Determination in the Mammalian Germline. Annual Review of Genetics, 51 (1), 265-285. doi: 10.1146/annurev-genet-120215-035449

Regulation of fetal male germ cell development by members of the TGFβ superfamily

Spiller, Cassy, Burnet, Guillaume and Bowles, Josephine (2017). Regulation of fetal male germ cell development by members of the TGFβ superfamily. Stem cell research, 24, 174-180. doi: 10.1016/j.scr.2017.07.016

Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis

Spiller, Cassy M. and Bowles, Josephine (2017). Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis. International Journal of Biochemistry & Cell Biology, 86, 22-25. doi: 10.1016/j.bioce1.2017.03.004

Mice lacking Hbp1 function are viable and fertile

Spiller, Cassy M., Wilhelm, Dagmar, Jans, David A., Bowles, Josephine and Koopman, Peter (2017). Mice lacking Hbp1 function are viable and fertile. PLoS One, 12 (1) e0170576, e0170576. doi: 10.1371/journal.pone.0170576

Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Spiller, Cassy M., Gillis, Ad J. M., Burnet, Guillaume, Stoop, Hans, Koopman, Peter, Bowles, Josephine and Looijenga, Leendert H. J. (2016). Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors. Molecular Oncology, 10 (4), 526-537. doi: 10.1016/j.molonc.2015.11.003

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

Holm, Jacob Bak, Mazaud-Guittot, Severine, Danneskiold-Samsoe, Niels Banhos, Chalmey, Clementine, Jensen, Benjamin, Norregard, Mette Marie, Hansen, Cecilie Hurup, Styrishave, Bjarne, Svingen, Terje, Vinggaard, Anne Marie, Koch, Holger Martin, Bowles, Josephine, Koopman, Peter, Jegou, Bernard, Kristiansen, Karsten and Kristensen, David Mobjerg (2016). Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility. Toxicological Sciences, 150 (1), 178-189. doi: 10.1093/toxsci/kfv332

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Bowles, Josephine, Feng, Chun-Wei, Miles, Kim, Ineson, Jessica, Spiller, Cassy and Koopman, Peter (2016). ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries. Nature Communications, 7 (1) 10845, 10845.1-10845.8. doi: 10.1038/ncomms10845

Culturing murine embryonic organs: pros, cons, tips and tricks

McClelland, Kathryn S. and Bowles, Josephine (2016). Culturing murine embryonic organs: pros, cons, tips and tricks. Differentiation, 91 (4-5), 50-56. doi: 10.1016/j.diff.2016.01.008

Germ cells influence cord formation and leydig cell gene expression during mouse testis development

Rios-Rojas, Clarissa, Spiller, Cassy, Bowles, Josephine and Koopman, Peter (2016). Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Developmental Dynamics, 245 (4), 433-444. doi: 10.1002/dvdy.24371

Agarose/gelatin immobilisation of tissues or embryo segments for orientated paraffin embedding and sectioning

McClelland, Kathryn S., Ng, Ee Ting and Bowles, Josephine (2015). Agarose/gelatin immobilisation of tissues or embryo segments for orientated paraffin embedding and sectioning. Differentiation, 91 (4-5), 68-71. doi: 10.1016/j.diff.2015.12.001

Purification and Transcriptomic analysis of mouse fetal leydig cells reveals candidate genes for specification of gonadal steroidogenic cells

McClelland, Kathryn S., Bell, Katrina, Larney, Christian, Harley, Vincent R., Sinclair, Andrew H., Oshlack, Alicia, Koopman, Peter A. and Bowles, Josephine (2015). Purification and Transcriptomic analysis of mouse fetal leydig cells reveals candidate genes for specification of gonadal steroidogenic cells. Biology of Reproduction, 92 (6), 145-145. doi: 10.1095/biolreprod.115.128918

Sex determination in mammalian germ cells

Spiller, Cassy M. and Bowles, Josephine (2015). Sex determination in mammalian germ cells. Asian Journal of Andrology, 17 (3), 427-432. doi: 10.4103/1008-682X.150037

On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?

Rios-Rojas, Clarissa, Bowles, Josephine and Koopman, Peter (2015). On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?. Reproduction, 149 (4), R181-R191. doi: 10.1530/REP-14-0663

Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos

McClelland, Kathryn S., Wainwright, Elanor N., Bowles, Josephine and Koopman, Peter (2015). Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos. PLoS One, 10 (1) e0114932, 1-18. doi: 10.1371/journal.pone.0114932

Structure-function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination

Zhao, Liang, Ng, Ee Ting, Davidson, Tara-Lynne, Longmuss, Enya, Urschitz, Johann, Elston, Marlee, Moisyadi, Stefan, Bowles, Josephine and Koopman, Peter (2014). Structure-function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination. Proceedings of the National Academy of Sciences, 111 (32), 11768-11773. doi: 10.1073/pnas.1400666111

A site-specific, single-copy transgenesis strategy to identify 5′ regulatory sequences of the mouse testis- determining gene Sry

Quinn, Alexander, Kashimada, Kenichi, Davidson, Tara-Lynne, Ng, Ee Ting, Chawengsaksophak, Kallayanee, Bowles, Josephine and Koopman, Peter (2014). A site-specific, single-copy transgenesis strategy to identify 5′ regulatory sequences of the mouse testis- determining gene Sry. PLoS One, 9 (4) e94813, 1-10. doi: 10.1371/journal.pone.0094813

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo

Bowles, Josephine, Secker, Genevieve, Nguyen, Christelle, Kazenwadel, Jan, Truong, Vy, Framptom, Emmanuelle, Curtis, Cameron, Skoczylas, Renae, Davidson, Tara-Lynn, Miura, Naoyuki, Hong, Young-Kwon, Koopman, Peter, Harvey, Natasha L. and François, Mathias (2014). Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo. Developmental Biology, 386 (1), 25-33. doi: 10.1016/j.ydbio.2013.12.008

Control of mammalian germ cell entry into meiosis

Feng, Chun-Wei, Bowles, Josephine and Koopman, Peter (2013). Control of mammalian germ cell entry into meiosis. Molecular and Cellular Endocrinology, 382 (1), 488-497. doi: 10.1016/j.mce.2013.09.026

Regulation of germ cell meiosis in the fetal ovary

Spiller, Cassy M., Bowles, Josephine and Koopman, Peter (2013). Regulation of germ cell meiosis in the fetal ovary. International Journal of Developmental Biology, 56 (10-12), 779-787. doi: 10.1387/ijdb.120142pk

Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors

Spiller, Cassy M., Bowles, Josephine and Koopman, Peter (2013). Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors. International Journal of Developmental Biology, 57 (2-4), 211-219. doi: 10.1387/ijdb.130028pk

Endogenous nodal signaling regulates germ cell potency during mammalian testis development

Spiller, Cassy M., Feng, Chun-Wei, Jackson, Andrew, Gillis, Ad J. M., Rolland, Antoine D., Looijenga, Leendert H. J., Koopman, Peter and Bowles, Josephine (2012). Endogenous nodal signaling regulates germ cell potency during mammalian testis development. Development, 139 (22), 4123-4132. doi: 10.1242/dev.083006

Precious cargo: regulation of sex-specific germ cell development in mice

Bowles, Josephine and Koopman, Peter A. (2012). Precious cargo: regulation of sex-specific germ cell development in mice. Sexual Development, 7 (1-3), 46-60. doi: 10.1159/000342072

Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis

DiTacchio, Luciano, Bowles, Josephine, Shin, Sook, Lim, Dae-Sik, Koopman, Peter and Janknecht, Ralf (2012). Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. Journal of Biological Chemistry, 287 (28), 23657-23666. doi: 10.1074/jbc.M111.320101

Initiating meiosis: The case for retinoic acid

Griswold, Michael D., Hogarth, Cathryn A., Bowles, Josephine and Koopman, Peter A. (2012). Initiating meiosis: The case for retinoic acid. Biology of Reproduction, 86 (2) 35, 35.1-35.7. doi: 10.1095/biolreprod.111.096610

Male sex determination: Insights into molecular mechanisms

McClelland, Kathryn, Bowles, Josephine and Koopman, Peter (2012). Male sex determination: Insights into molecular mechanisms. Asian Journal of Andrology, 14 (1), 164-171. doi: 10.1038/aja.2011.169

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

Kashimada, Kenichi, Svingen, Terje, Feng, Chun-Wei, Pelosi, Emanuele, Bagheri-Fam, Stefan, Harley, Vincent R., Schlessinger, David, Bowles, Josephine and Koopman, Peter (2011). Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice. The FASEB Journal, 25 (10), 3561-3569. doi: 10.1096/fj.11-184333

Expression and functional analysis of Dkk1 during early gonadal development

Combes, A. N., Bowles, J., Feng, C. -W., Chiu, H. S., Khoo, P. L., Jackson, A., Little, M. H., Tam, P. P. L. and Koopman, P. (2011). Expression and functional analysis of Dkk1 during early gonadal development. Sexual Development, 5 (3), 124-130. doi: 10.1159/000327709

FGF9 suppresses meiosis and promotes male germ cell fate in mice

Bowles, Josephine, Feng, Chun-Wei, Spiller, Cassy, Davidson, Tara-Lynne, Jackson, Andrew and Koopman, Peter (2010). FGF9 suppresses meiosis and promotes male germ cell fate in mice. Developmental Cell, 19 (3), 440-449. doi: 10.1016/j.devcel.2010.08.010

Sex determination in mammalian germ cells: extrinsic versus intrinsic factors

Bowles, Josephine and Koopman, Peter (2010). Sex determination in mammalian germ cells: extrinsic versus intrinsic factors. Reproduction, 139 (6), 943-958. doi: 10.1530/REP-10-0075

Profiles of gonadal gene expression in the developing bovine embryo

Ross, D.G.F., Bowles, J., Hope, M., Lehnert, S. and Koopman, P. (2009). Profiles of gonadal gene expression in the developing bovine embryo. Sexual Development, 3 (5), 273-283. doi: 10.1159/000252791

Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: Implications for retinoid balance in gonad development

Bowles, Josephine, Feng, Chun-Wei, Knight, Deon, Smith, Craig A., Roeszler, Kelly N., Bagheri-Fam, Stefan, Harley, Vincent R., Sinclair, Andrew H. and Koopman, Peter (2009). Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: Implications for retinoid balance in gonad development. Developmental Dynamics, 238 (8), 2073-2080. doi: 10.1002/dvdy.22024

New insights into SRY regulation through identification of 5' conserved sequences

Ross, Diana G.F., Bowles, Josephine, Koopman, Peter and Lehnert, Sigrid (2008). New insights into SRY regulation through identification of 5' conserved sequences. BMC Molecular Biology, 9 (1) 85, 85.1-85.15. doi: 10.1186/1471-2199-9-85

Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid

Smith, Craig, Roeszler, Kelly, Bowles, Josephine, Koopman, Peter and Sinclair, Andrew (2008). Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid. BMC Developmental Biology, 8 (85) 85. doi: 10.1186/1471-213X-8-85

Characterisation of urogenital ridge gene expression in the human embryonal carcinoma cell line NT2/D1

Knower, K. C., Sim, H., McClive, P. J., Bowles, J., Koopman, P., Sinclair, A. H. and Harley, V. R. (2007). Characterisation of urogenital ridge gene expression in the human embryonal carcinoma cell line NT2/D1. Sexual Development, 1 (2), 114-126. doi: 10.1159/000100033

Retinoic acid, meiosis and germ cell fate in mammals

Bowles, J. and Koopman, P. (2007). Retinoic acid, meiosis and germ cell fate in mammals. Development, 134 (19), 3401-3411. doi: 10.1242/dev.001107

In situ hybridization of whole-mount embryos

Hargrave, Murray, Bowles, Josephine and Koopman, Peter (2006). In situ hybridization of whole-mount embryos. Methods in Molecular Biology, 326, 103-113. doi: 10.1385/1-59745-007-3:103

Retinoid signaling determines germ cell fate in mice

Bowles, Josephine, Knight, Deon, Smith, Christopher, Wilhelm, Dagmar, Richman, Joy, Mamiya, Satoru, Yashiro, Kenta, Chawengsaksophak, Kallayanee, Wilson, Megan J., Rossant, Janet, Hamada, Hiroshi and Koopman, Peter (2006). Retinoid signaling determines germ cell fate in mice. Science, 312 (5773), 596-600. doi: 10.1126/science.1125691

The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b

Simpson, Fiona, Lammerts van Bueren, Kelly L., Butterfield, Natalie, Bennetts, Jennifer S., Bowles, Josephine, Adolphe, Christelle, Simms, Lisa A., Young, Joanne, Walsh, Michael D., Leggett, Barbara, Fowles, Lindsay F. and Wicking, Carol (2006). The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b. Experimental Cell Research, 312 (1), 73-85. doi: 10.1016/j.yexcr.2005.09.020

The matricellular protein SPARC is internalized in Sertoli, Leydig, and germ cells during testis differentiation

Wilson, M. J., Bowles, J. and Koopman, P. (2006). The matricellular protein SPARC is internalized in Sertoli, Leydig, and germ cells during testis differentiation. Molecular Reproduction And Development, 73 (5), 531-539. doi: 10.1002/mrd.20394

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

Wilhelm, Dagmar, Martinson, Fred, Bradford, Stephen, Wilson, Megan J., Combes, Alexander N., Beverdam, Annemiek, Bowles, Josephine, Mizusaki, Hirofumi and Koopman, Peter (2005). Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Developmental Biology, 287 (1), 111-124. doi: 10.1016/j.ydbio.2005.08.039

Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development

Loffler, Kelly A., Combes, Alexander N., Wilhelm, Dagmar, Beverdam, Annemiek, Bowles, Jo and Koopman, Peter (2005). Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development. Molecular Genetics and Metabolism, 86 (1-2), 286-292. doi: 10.1016/j.ymgme.2005.06.013

Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis

Jeanes, A., Wilhelm, D., Wilson, M. J., Bowles, J., McClive, P. J., Sinclair, A. H. and Koopman, P. (2005). Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis. Reproduction, 130 (4), 509-516. doi: 10.1530/rep.1.00718

HMG box transcription factor gene Hbp1 is expressed in germ cells of the developing mouse testis

Smith, James M., Bowles, Josephine, Wilson, Megan and Koopman, Peter (2004). HMG box transcription factor gene Hbp1 is expressed in germ cells of the developing mouse testis. Developmental Dynamics, 230 (2), 366-370. doi: 10.1002/dvdy.20053

Expression of the tudor-related gene Tdrd5 during development of the male germline in mice

Smith, J. M., Bowles, J., Wilson, M., Teasdale, R. D. and Koopman, P. (2004). Expression of the tudor-related gene Tdrd5 during development of the male germline in mice. Gene Expression Patterns, 4 (6), 701-705. doi: 10.1016/j.modgep.2004.04.002

Overexpression of sonic hedgehog suppresses embryonic hair follicle morphogenesis

Ellis, Tammy, Smyth, Ian, Riley, Emily, Bowles, Josephine, Adolphe, Christelle, Rothnagel, Joseph A., Wicking, Carol and Wainwright, Brandon J. (2003). Overexpression of sonic hedgehog suppresses embryonic hair follicle morphogenesis. Developmental Biology, 263 (2), 203-215. doi: 10.1016/S0012-1606(03)00394-4

Extensive vascularization of developing mouse ovaries revealed by caveolin-1 expression

Bullejos, Monica, Bowles, Jo and Koopman, Peter (2002). Extensive vascularization of developing mouse ovaries revealed by caveolin-1 expression. Developmental Dynamics, 225 (1), 95-99. doi: 10.1002/dvdy.10128

Expression-based strategies for discovery of genes involved in testis and ovary development

Koopman, P., Bullejos, M., Loffler, K. and Bowles, J. (2002). Expression-based strategies for discovery of genes involved in testis and ovary development. Genetics And Biology of Sex Determination, 244, 240-252.

New clues to the puzzle of mammalian sex determination

Bowles, Josephine and Koopman, Peter (2001). New clues to the puzzle of mammalian sex determination. Genome Biology, 2 (9), 1-4. doi: 10.1186/gb-2001-2-9-reviews1025

New clues to the puzzle of mammalian sex determination

Bowles, Josephine and Koopman, Peter (2001). New clues to the puzzle of mammalian sex determination. Genome Biology, 2 (9). doi: 10.1186/gb-2001-2-9-reviews1025

Characterisation of Crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern

Georgas, Kylie, Bowles, Josephine, Yamada, Toshiya, Koopman, Peter and Little, Melissa H. (2000). Characterisation of Crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern. Developmental Dynamics, 219 (4), 582-587. doi: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1072>3.0.CO;2-I

Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators

Bowles, J., Schepers, G. and Koopman, P. (2000). Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Developmental Biology, 227 (2), 239-255. doi: 10.1006/dbio.2000.9883

The maize CR4 receptor-like kinase mediates a growth factor-like differentiation response

Bowles, Josephine, Bullejos, Monica and Koopman, Peter (2000). The maize CR4 receptor-like kinase mediates a growth factor-like differentiation response. Genesis, 27 (3), 104-116. doi: 10.1002/1526-968X(200007)27:3<104::AID-GENE30>3.0.CO;2-I

Screening for novel mammalian sex-determining genes using expression cloning and microarray approaches

Bowles, Josephine, Bullejos, Monica and Koopman, Peter (2000). Screening for novel mammalian sex-determining genes using expression cloning and microarray approaches. Australian Biochemist, 31 (1), 4-6.

A substractive gene expression screen suggests a role for vanin-1 in testis development in mice

Bowles, J., Bullejos, M. and Koopman, P. A. (2000). A substractive gene expression screen suggests a role for vanin-1 in testis development in mice. Genesis, 27 (3), 124-135. doi: 10.1002/1526-968X(200007)27:3<124::AID-GENE50>3.0.CO;2-E

Mice null for Sox18 are viable and display a mild coat defect

Pennisi, D., Bowles, J, Nagy, A., Muscat, G. and Koopman, P. (2000). Mice null for Sox18 are viable and display a mild coat defect. Molecular and Cell Biology, 20 (24), 9331-9336. doi: 10.1128/MCB.20.24.9331-9336.2000

Sry requires a CAG repeat domain for male sex determination in Mus musculus

Bowles, Josephine, Cooper, Leanne, Berkman, Jennifer and Koopman, Peter (1999). Sry requires a CAG repeat domain for male sex determination in Mus musculus. Nature Genetics, 22 (4), 405-408. doi: 10.1038/11981

Ectopic expression of Sonic Hedgehog from the human Keratin 1 promoter gives rise to limb abnormalities and skin lesions in transgenic mice.

Smyth, I, Bowles, J, Rothnagel, J, Wicking, C and Wainwright, B (1999). Ectopic expression of Sonic Hedgehog from the human Keratin 1 promoter gives rise to limb abnormalities and skin lesions in transgenic mice.. American Journal of Human Genetics, 65 (4), A371-A371.

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

Ng, Ling-Jim, Wheatley, Susan, Muscat, George E. O., Conway-Campbell, John, Bowles, Jo, Wright, Edwina, Bell, Donald M., Cheah, Kathryn S. E. and Koopman, Peter (1997). SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Developmental Biology, 183 (1), 108-121. doi: 10.1006/dbio.1996.8487

Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients

Shaw, J., Bowles, J., Koopman, P., Wood, E. C. and Trounson, A. O. (1996). Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. Human Reproduction, 11 (8), 1668-1673. doi: 10.1093/oxfordjournals.humrep.a019467

Molecular genetic approaches to parasite identification: Their value in diagnostic parasitology and systematics

McManus, DP and Bowles, J (1996). Molecular genetic approaches to parasite identification: Their value in diagnostic parasitology and systematics. International Journal for Parasitology, 26 (7), 687-704. doi: 10.1016/0020-7519(96)82612-9

Expression of a linear Sry transcript in the mouse genital ridge

Jeske, Yvette W. A., Bowles, Josephine, Greenfield, Andy and Koopman, Peter (1995). Expression of a linear Sry transcript in the mouse genital ridge. Nature Genetics, 10 (4), 480-482. doi: 10.1038/ng0895-480

A Molecular Phylogeny of the Human Schistosomes

Bowles, J, Blair, D and McManus, DP (1995). A Molecular Phylogeny of the Human Schistosomes. Molecular Phylogenetics and Evolution, 4 (2), 103-109. doi: 10.1006/mpev.1995.1011

A Molecular Phylogeny of the Genus Echinococcus

Bowles, J, Blair, D and McManus, DP (1995). A Molecular Phylogeny of the Genus Echinococcus. Parasitology, 110 (03), 317-328. doi: 10.1017/S0031182000080902

Molecular-Genetic Characterization of the Cervid Strain (Northern Form) of Echinococcus-Granulosus

Bowles, J, Blair, D and McManus, DP (1994). Molecular-Genetic Characterization of the Cervid Strain (Northern Form) of Echinococcus-Granulosus. Parasitology, 109 (02), 215-221. doi: 10.1017/S0031182000076332

Asian (Taiwan) Taenia - Species or Strain

McManus, DP and Bowles, J (1994). Asian (Taiwan) Taenia - Species or Strain. Parasitology Today, 10 (7), 273-275. doi: 10.1016/0169-4758(94)90145-7

A Molecular-Genetic Survey Indicates the Presence of a Single, Homogeneous Strain of Echinococcus-Granulosus in North-Western China

McManus, DP, Ding, ZX and Bowles, J (1994). A Molecular-Genetic Survey Indicates the Presence of a Single, Homogeneous Strain of Echinococcus-Granulosus in North-Western China. Acta Tropica, 56 (1), 7-14. doi: 10.1016/0001-706X(94)90035-3

Genetic-Characterization of the Asian Taenia, a Newly Described Taeniid Cestode of Humans

Bowles, J and McManus, DP (1994). Genetic-Characterization of the Asian Taenia, a Newly Described Taeniid Cestode of Humans. American Journal of Tropical Medicine and Hygiene, 50 (1), 33-44. doi: 10.4269/ajtmh.1994.50.1.TM0500010033

Nuclear and Mitochondrial Genetic-Markers Highly Conserved Between Chinese and Philippine Schistosoma-Japonicum

Bowles, J, Hope, M, Tiu, WU, Liu, XS and McManus, DP (1993). Nuclear and Mitochondrial Genetic-Markers Highly Conserved Between Chinese and Philippine Schistosoma-Japonicum. Acta Tropica, 55 (4), 217-229. doi: 10.1016/0001-706X(93)90079-Q

Nadh Dehydrogenase-1 Gene-Sequences Compared for Species and Strains of the Genus Echinococcus

Bowles, J and McManus, DP (1993). Nadh Dehydrogenase-1 Gene-Sequences Compared for Species and Strains of the Genus Echinococcus. International Journal for Parasitology, 23 (7), 969-972. doi: 10.1016/0020-7519(93)90065-7

Molecular Variation in Echinococcus

Bowles, J and McManus, DP (1993). Molecular Variation in Echinococcus. Acta Tropica, 53 (3-4), 291-305. doi: 10.1016/0001-706X(93)90035-A

Molecular Examination of the Sympatry and Distribution of Sheep and Camel Strains of Echinococcus-Granulosus in Kenya

Wachira, TM, Bowles, J, Zeyhle, E and McManus, DP (1993). Molecular Examination of the Sympatry and Distribution of Sheep and Camel Strains of Echinococcus-Granulosus in Kenya. American Journal of Tropical Medicine and Hygiene, 48 (4), 473-479. doi: 10.4269/ajtmh.1993.48.473

Rapid Discrimination of Echinococcus Species and Strains Using a Polymerase Chain Reaction-Based Rflp Method

Bowles, J and McManus, DP (1993). Rapid Discrimination of Echinococcus Species and Strains Using a Polymerase Chain Reaction-Based Rflp Method. Molecular and Biochemical Parasitology, 57 (2), 231-240. doi: 10.1016/0166-6851(93)90199-8

Genetic-Variants Within the Genus Echinococcus Identified by Mitochondrial-Dna Sequencing

Bowles, J, Blair, D and McManus, DP (1992). Genetic-Variants Within the Genus Echinococcus Identified by Mitochondrial-Dna Sequencing. Molecular and Biochemical Parasitology, 54 (2), 165-174. doi: 10.1016/0166-6851(92)90109-W

Cattle Strain of Echinococcus-Granulosus and Human Infection

Bowles, J, Vanknapen, F and McManus, D (1992). Cattle Strain of Echinococcus-Granulosus and Human Infection. Lancet, 339 (8805), 1358-1358. doi: 10.1016/0140-6736(92)92003-X

A Genetic Comparison of Human and Wildlife Isolates of Echinococcus-Granulosus in Queensland - Public-Health Implications

Hope, M, Bowles, J, Prociv, P and McManus, DP (1992). A Genetic Comparison of Human and Wildlife Isolates of Echinococcus-Granulosus in Queensland - Public-Health Implications. Medical Journal of Australia, 156 (1), 27-30.

Some recent advances in the molecular characterization of Echinococcus and Taenia solium

McManus, D. P., Bowles, J., Leggatt, G. and Garcia-Zepeda, E. (1991). Some recent advances in the molecular characterization of Echinococcus and Taenia solium. The Southeast Asian journal of tropical medicine and public health, 22 Suppl, 256-261.

A Reconsideration of the Echinococcus-Granulosus Strain Situation in Australia Following Rflp Analysis of Cystic Material

Hope, M, Bowles, J and McManus, DP (1991). A Reconsideration of the Echinococcus-Granulosus Strain Situation in Australia Following Rflp Analysis of Cystic Material. International Journal for Parasitology, 21 (4), 471-475. doi: 10.1016/0020-7519(91)90106-H

Gene editing of the multi-copy H2A.B gene family by a single pair of TALENs in mice

Anuar, Nur Diana, Field, Matt, Kurscheid, Sebastian, Zhang, Lei, Rebar, Edward, Gregory, Philip, Bowles, Josephine, Koopman, Peter, Tremethick, David J. and Soboleva, Tatiana (2018). Gene editing of the multi-copy H2A.B gene family by a single pair of TALENs in mice. LONDON: BIOMED CENTRAL LTD.

Sex fate determination in the germ line

Bowles, Josephine, Feng, Chun-Wei, Davidson, Tara and Koopman, Peter (2009). Sex fate determination in the germ line. 42nd Annual Meeting of the Society for the Study of Reproduction, Pittsburgh PA, 8-22 July 2009. United States: Society for the Study of Reproduction.

The production of male of-only offspring in beef cattle - a proof of principle project

Farkas, D., Bowles, J., Lehnert, S.A. and Koopman, P.A. (2006). The production of male of-only offspring in beef cattle - a proof of principle project. 7th Transgenic Technology Meeting (TT2007), Brisbane, Qld, Australia, 12-14 February, 2007. Dordrecht,The Netherlands: Springer. doi: 10.1007/s11248-006-9047-x

Entry of germ cells into meiosis is induced by retinoic acid in mice

Koopman, P., Knight, D., Smith, C., Wilson, M., Wilhelm, D., Richman, J., Rossant, J. and Bowles, J. (2005). Entry of germ cells into meiosis is induced by retinoic acid in mice.

Entry of mouse embryonic germ cells into meiosis is induced by retinoic acid

Bowles, J., Knight, D., Smith, C., Wilson, M., Wilhelm, D., Richman, J., Rossant, J. and Koopman, P. (2005). Entry of mouse embryonic germ cells into meiosis is induced by retinoic acid.

The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumour suppressor product p33ING1

Simpson, F., van Bueren, Lammerts K., Fowles, L., Berkman, J., Butterfield, N., Bowles, J., Adolphe, C., Simms, L., Young, J., Walsh, M. and Wicking, C. (2005). The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumour suppressor product p33ING1. Unknown, Unknown, Unknown. Amsterdam, Netherlands: Elsevier Science.

Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours

Bowles, J., Teasdale, R. D., James, K. M. and Koopman, P. A. (2003). Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours. Vertebrate Sex Determination, Kona, Hawaii, 24-28 March, 2003. Basil, Switzerland: Karger. doi: 10.1159/000074346

Expression-based strategies for discovery of genes involved in testis and ovary development

Koopman, P.A., Bullejos Martin, M., Loffler, K.A. and Bowles, J. (2002). Expression-based strategies for discovery of genes involved in testis and ovary development. The genetics and biology of sex determination, Novartis Foundation, London, 1-3 May, 2001. Chichester, West Sussex, England ; New York, NY: Wiley & Sons.

Assessment of candidate ovarian-determining genes.

Loffler, KA, Bowles, J and Koopman, P (2001). Assessment of candidate ovarian-determining genes.. SAN DIEGO: ACADEMIC PRESS INC.

Regulation of male sexual development by Sry and Sox9

Koopman, P., Bullejos, M. and Bowles, J. (2001). Regulation of male sexual development by Sry and Sox9. New York: John Wiley & Sons, Inc.. doi: 10.1002/jez.1089

Searching for missing pieces of the sex-determination puzzle

Bullejos Martin, M., Bowles, J. and Koopman, P. A. (2001). Searching for missing pieces of the sex-determination puzzle. USA: Wiley-Liss Inc.. doi: 10.1002/jez.1095

Mouse SRY requires a CAG repeat domain for male sex determination

Bowles, J., Cooper, L., Berkman, J. and Koopman, P. (1999). Mouse SRY requires a CAG repeat domain for male sex determination. -, -, 1999. Chicago, IL United States: University of Chicago Press.

Aetiology of the skeletal dysmorphology syndrome campomelic dysplasia: Expression of the Sox9 gene during chondrogenesis in mouse embryos

Wheatley, Susan, Wright, Edwina, Jeske, Yvette, Mccormack, Andrew, Bowles, Josephine and Koopman, Peter (1996). Aetiology of the skeletal dysmorphology syndrome campomelic dysplasia: Expression of the Sox9 gene during chondrogenesis in mouse embryos. Conference on Molecular and Developmental Biology of Cartilage, Bethesda, MD, United States, 27-30 September 1995. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/j.1749-6632.1996.tb56306.x