Professor Andrew Barbour is an academic general surgeon who specialises in upper gastrointestinal, pancreatic, melanoma and sarcoma surgery.
On completion of his training, Dr Barbour worked at the Bristol Royal Infirmary as an Upper Gastrointestinal and Hepatobiliary Surgery Fellow and then as a Surgical Oncology Fellow at the Memorial Sloan-Kettering Cancer Centre, New York.
Professor Andrew Barbour specializes in the treatment of oesophageal, gastric, and pancreatic diseases, as well as melanoma and soft tissue tumours. He has expertise in minimally invasive treatments these conditions, including robotic surgery, minimally invasive oesophagectomy, laparoscopic anti-reflux surgery (fundoplication), laparoscopic gastrectomy, and laparoscopic pancreatectomy.
Professor Barbour’s research interests are in the treatment of cancer. His academic interests have encompassed the areas of 1) clinical research, including randomised controlled clinical trials, 2) laboratory based research, including molecular biology pertinent to upper gastrointestinal disease, pancreatic cancer and melanoma, 3) translational research integrating the laboratory and clinical domains, and 4) health-related quality of life and patient reported outcomes research.
As a clinical researcher, Prof Barbour has been active in the conduct of clinical trials at Phase I, II and III levels. He was the Principal Investigator for investigator initiated, multicentre phase II trials in oesophageal (DOCTOR trial) and pancreatic cancer (GAP Trial), funded by the NH&MRC and sponsored by the Australasian Gastrointestinal Trials Group (AGITG). Both of these national trials include biological substudies with tumour tissue and blood banking and subsequent molecular analyses aimed at answering specific questions, including the identification of biomarkers of response to therapy. These studies are aimed at developing personalized, precision therapy for cancer. The DOCTOR trial was the first trial to use PET scans to “tailor” or “personalize” therapy for patients with oesophageal cancer. The GAP trial has shown that pre-operative chemotherapy is a safe strategy for patients with pancreatic cancer. Building on the GAP trial, the AGITG has undertaken the MRFF funded MASTERPLAN clinical trial for pancreatic cancer exploring th e role of stereotactic radiation in pancreatic cancer. Professor Barbour is the Chair of the AGITG Upper GI working party and a member of the AGITG Board.
Prof Barbour is a translational researcher at the School of Medicine, The University of Queensland. He is the head of Surgical Oncology Lab at the School of Medicine. His research has focused on using genomic, epigenomic, mRNA expression and next generation sequencing data to classify oesophageal adenocarcinoma (OAC), pancreatic cancer and melanoma and to identify biomarkers of outcome. His lab team was the first to identify genomic catastrophes as potential drivers for oesophageal adenocarcinoma. In addition, his lab is seeking to identify genetic markers in melanoma that will identify patients at high risk for recurrence following surgery and to identify patients who will benefit from the current exciting advances in treatment for advanced melanoma. His work in melanoma is supported by a Queensland Advancing Clinical Research Fellowship. He was also a member of the Australian Pancreatic Cancer Genome Initiative (APGI) that has published several key studies that have improved our understanding of pancreatic cancer. His lab is currently undertaking studies using next generation sequencing of tumour and circulating tumour DNA. Professor Barbour is the Chief Investigator for the Cancer Evolution Biobank based at the Translational Research Institute. This biobank contains tumour tissue and blood from patients with melanoma, oesophageal or gastric cancer linked to clinical outcomes and supports several research projects.
Journal Article: ctDNA: a promising biomarker for predicting recurrence in BRAF-negative melanoma patients
Aoude, Lauren G., Brosda, Sandra, Ng, Jessica, Lonie, James M., Belle, Clemence J., Patel, Kalpana, Koufariotis, Lambros T., Wood, Scott, Atkinson, Victoria, Smithers, B. Mark, Pearson, John V., Waddell, Nicola, Barbour, Andrew P. and Bonazzi, Vanessa F. (2023). ctDNA: a promising biomarker for predicting recurrence in BRAF-negative melanoma patients. Journal of Molecular Diagnostics, 25 (10), 771-781. doi: 10.1016/j.jmoldx.2023.06.014
Journal Article: C‐reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients
Bonazzi, Vanessa F., Aoude, Lauren G., Brosda, Sandra, Bradford, Julia J., Lonie, James M., Loffler, Kelly A., Gartside, Michael G., Patel, Kalpana, Mukhopadhyay, Pamela, Keane, Colm, Gebski, Val, Kench, James G., Goldstein, David, Waddell, Nicola, Barbour, Andrew P. and the Australasian Gastro‐Intestinal Trials Group (AGITG) GAP investigators (2023). C‐reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients. Asia-Pacific Journal of Clinical Oncology. doi: 10.1111/ajco.13993
Journal Article: Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy
M. Naeini, Marjan, Newell, Felicity, Aoude, Lauren G., Bonazzi, Vanessa F., Patel, Kalpana, Lampe, Guy, Koufariotis, Lambros T., Lakis, Vanessa, Addala, Venkateswar, Kondrashova, Olga, Johnston, Rebecca L., Sharma, Sowmya, Brosda, Sandra, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Xu, Qinying, Thomas, Janine, Walpole, Euan, Tao Mai, G., Ackland, Stephen P., Martin, Jarad, Burge, Matthew, Finch, Robert, Karapetis, Christos S., Shannon, Jenny, Nott, Louise, Bohmer, Robert, Wilson, Kate ... Waddell, Nicola (2023). Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy. Nature Communications, 14 (1) 3155, 3155. doi: 10.1038/s41467-023-38891-x
(2023–2026) CCQ Accelerating Collaborative Cancer Research
(2021–2024) Cancer Council Queensland
Improving outcomes for patients with melanoma brain metastases
(2020–2025) Community Skilling & Disability Support Service Inc (trading name: Civic Solutions)
Harnessing tumour immune responses in oesophageal cancer: towards better personalised therapeutic strategies
Doctor Philosophy
(2020) Doctor Philosophy
Genomic investigations in oesophageal adenocarcinoma: towards biomarkers of prognosis
(2013) Doctor Philosophy
Clinical practice guidelines for the management of melanoma in Australia and New Zealand
Aitken, Joanne F., Barbour, Andrew, Burmeister, Bryan, Taylor, Simon, Walpole, Euan, Australian Cancer Network, Smithers, Bernhard M. and Melanoma Guidelines Revision Working Party (2008). Clinical practice guidelines for the management of melanoma in Australia and New Zealand. Sydney, Australia: Cancer Council Australia; Australian Cancer Network; Ministry of Health, New Zealand.
Thoracoscopic and laparoscopic esophagectomy
Smithers, B. Mark, Thomson, Iain and Barbour, Andrew (2018). Thoracoscopic and laparoscopic esophagectomy. Operative thoracic surgery. (pp. 377-386) edited by Larry R. Kaiser, Sarah K. Thompson and Glyn G. Jamieson. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315113777
ctDNA: a promising biomarker for predicting recurrence in BRAF-negative melanoma patients
Aoude, Lauren G., Brosda, Sandra, Ng, Jessica, Lonie, James M., Belle, Clemence J., Patel, Kalpana, Koufariotis, Lambros T., Wood, Scott, Atkinson, Victoria, Smithers, B. Mark, Pearson, John V., Waddell, Nicola, Barbour, Andrew P. and Bonazzi, Vanessa F. (2023). ctDNA: a promising biomarker for predicting recurrence in BRAF-negative melanoma patients. Journal of Molecular Diagnostics, 25 (10), 771-781. doi: 10.1016/j.jmoldx.2023.06.014
C‐reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients
Bonazzi, Vanessa F., Aoude, Lauren G., Brosda, Sandra, Bradford, Julia J., Lonie, James M., Loffler, Kelly A., Gartside, Michael G., Patel, Kalpana, Mukhopadhyay, Pamela, Keane, Colm, Gebski, Val, Kench, James G., Goldstein, David, Waddell, Nicola, Barbour, Andrew P. and the Australasian Gastro‐Intestinal Trials Group (AGITG) GAP investigators (2023). C‐reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients. Asia-Pacific Journal of Clinical Oncology. doi: 10.1111/ajco.13993
M. Naeini, Marjan, Newell, Felicity, Aoude, Lauren G., Bonazzi, Vanessa F., Patel, Kalpana, Lampe, Guy, Koufariotis, Lambros T., Lakis, Vanessa, Addala, Venkateswar, Kondrashova, Olga, Johnston, Rebecca L., Sharma, Sowmya, Brosda, Sandra, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Xu, Qinying, Thomas, Janine, Walpole, Euan, Tao Mai, G., Ackland, Stephen P., Martin, Jarad, Burge, Matthew, Finch, Robert, Karapetis, Christos S., Shannon, Jenny, Nott, Louise, Bohmer, Robert, Wilson, Kate ... Waddell, Nicola (2023). Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy. Nature Communications, 14 (1) 3155, 3155. doi: 10.1038/s41467-023-38891-x
Narendra, Aaditya and Barbour, Andrew (2023). Introducing robotic oesophagectomy into an Australian practice: an assessment of the early procedural outcomes and learning curve. ANZ Journal of Surgery, 93 (5), 1300-1305. doi: 10.1111/ans.18445
Wu, Michael Yulong, McGregor, Richard J., Scott, Justin, Smithers, B. Mark, Thomas, Janine, Frankel, Adam, Barbour, Andrew and Thomson, Iain (2023). Textbook outcomes for oesophagectomy: A valid composite measure assessment tool for surgical performance in a specialist unit. European Journal of Surgical Oncology, 49 (9) 106897, 106897. doi: 10.1016/j.ejso.2023.03.233
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
Ballinger, Mandy L., Pattnaik, Swetansu, Mundra, Piyushkumar A., Zaheed, Milita, Rath, Emma, Priestley, Peter, Baber, Jonathan, Ray-Coquard, Isabelle, Isambert, Nicholas, Causeret, Sylvain, van der Graaf, Winette T.A., Puri, Ajay, Duffaud, Florence, Le Cesne, Axel, Seddon, Beatrice, Chandrasekar, Coonoor, Schiffman, Joshua D., Brohl, Andrew S., James, Paul A., Kurtz, Jean-Emmanuel, Penel, Nicolas, Myklebost, Ola, Meza-Zepeda, Leonardo A., Pickett, Hilda, Kansara, Maya, Waddell, Nicola, Kondrashova, Olga, Pearson, John V., Barbour, Andrew P. ... Thomas, David M. (2023). Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science, 379 (6629), 253-260. doi: 10.1126/science.abj4784
Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Jiao, Wei, Kaiser, Vera B., Karlic, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N. ... von Mering, Christian (2022). Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns (Nature Communications, (2020), 11, 1, (728), 10.1038/s41467-019-13825-8). Nature Communications, 13 (1) 7573. doi: 10.1038/s41467-022-32329-6
Shuai, Shimin, Abascal, Federico, Amin, Samirkumar B., Bader, Gary D., Bandopadhayay, Pratiti, Barenboim, Jonathan, Beroukhim, Rameen, Bertl, Johanna, Boroevich, Keith A., Brunak, Søren, Campbell, Peter J., Carlevaro-Fita, Joana, Chakravarty, Dimple, Chan, Calvin Wing Yiu, Chen, Ken, Choi, Jung Kyoon, Deu-Pons, Jordi, Dhingra, Priyanka, Diamanti, Klev, Feuerbach, Lars, Fink, J. Lynn, Fonseca, Nuno A., Frigola, Joan, Gambacorti-Passerini, Carlo, Garsed, Dale W., Gerstein, Mark, Getz, Gad, Guo, Qianyun, Gut, Ivo G. ... von Mering, Christian (2022). Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (Nature Communications, (2020), 11, 1, (734), 10.1038/s41467-019-13929-1). Nature Communications, 13 (1) 7571. doi: 10.1038/s41467-022-32343-8
Paczkowska, Marta, Barenboim, Jonathan, Sintupisut, Nardnisa, Fox, Natalie S., Zhu, Helen, Abd-Rabbo, Diala, Mee, Miles W., Boutros, Paul C., Abascal, Federico, Amin, Samirkumar B., Bader, Gary D., Beroukhim, Rameen, Bertl, Johanna, Boroevich, Keith A., Brunak, Søren, Campbell, Peter J., Carlevaro-Fita, Joana, Chakravarty, Dimple, Chan, Calvin Wing Yiu, Chen, Ken, Choi, Jung Kyoon, Deu-Pons, Jordi, Dhingra, Priyanka, Diamanti, Klev, Feuerbach, Lars, Fink, J. Lynn, Fonseca, Nuno A., Frigola, Joan, Gambacorti-Passerini, Carlo ... von Mering, Christian (2022). Author Correction: Integrative pathway enrichment analysis of multivariate omics data (Nature Communications, (2020), 11, 1, (735), 10.1038/s41467-019-13983-9). Nature Communications, 13 (1) 7570. doi: 10.1038/s41467-022-32342-9
Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132
Comparative genomics provides etiological and biological insights into melanoma subtypes
Newell, Felicity, Johansson, Peter A., Wilmott, James S., Nones, Katia, Lakis, Vanessa, Pritchard, Antonia L., Lo, Serigne N., Rawson, Robert V., Kazakoff, Stephen H., Colebatch, Andrew J., Koufariotis, Lambros T., Ferguson, Peter M., Wood, Scott, Leonard, Conrad, Law, Matthew H., Brooks, Kelly M., Broit, Natasa, Palmer, Jane M., Couts, Kasey L., Vergara, Ismael A., Long, Georgina V., Barbour, Andrew P., Nieweg, Omgo E., Shivalingam, Brindha, Robinson, William A., Stretch, Jonathan R., Spillane, Andrew J., Saw, Robyn P.M., Shannon, Kerwin F. ... Hayward, Nicholas K. (2022). Comparative genomics provides etiological and biological insights into melanoma subtypes. Cancer Discovery, 12 (12), OF1-OF24. doi: 10.1158/2159-8290.cd-22-0603
Ramarao-Milne, P, Kondrashova, O, Patch, A-M, Nones, K, Koufariotis, L T, Newell, F, Addala, V, Lakis, V, Holmes, O, Leonard, C, Wood, S, Xu, Q, Mukhopadhyay, P, Naeini, M M, Steinfort, D, Williamson, J P, Bint, M, Pahoff, C, Nguyen, P T, Twaddell, S, Arnold, D, Grainge, C, Basirzadeh, F, Fielding, D, Dalley, A J, Chittoory, H, Simpson, P T, Aoude, L G, Bonazzi, V F ... Waddell, N (2022). Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels. ESMO Open, 7 (4) 100540, 1-11. doi: 10.1016/j.esmoop.2022.100540
Nilsson, Magnus, Olafsdottir, Halla, Alexandersson von Döbeln, Gabriella, Villegas, Fernanda, Gagliardi, Giovanna, Hellström, Mats, Wang, Qiao-Li, Johansson, Hemming, Gebski, Val, Hedberg, Jakob, Klevebro, Fredrik, Markar, Sheraz, Smyth, Elizabeth, Lagergren, Pernilla, Al-Haidari, Ghazwan, Rekstad, Lars Cato, Aahlin, Eirik Kjus, Wallner, Bengt, Edholm, David, Johansson, Jan, Szabo, Eva, Reynolds, John V., Pramesh, C. S., Mummudi, Naveen, Joshi, Amit, Ferri, Lorenzo, Wong, Rebecca KS, O’Callaghan, Chris, Lukovic, Jelena ... Lordick, Florian (2022). Neoadjuvant chemoradiotherapy and surgery for esophageal squamous cell carcinoma versus definitive chemoradiotherapy with salvage surgery as needed: The study protocol for the randomized controlled NEEDS trial. Frontiers in Oncology, 12 917961. doi: 10.3389/fonc.2022.917961
Molendijk, Jeffrey, Kolka, Cathryn M., Cairns, Henry, Brosda, Sandra, Mohamed, Ahmed, Shah, Alok K., Brown, Ian, Hodson, Mark P., Hennessy, Thomas, Liu, Guanghao, Stoll, Thomas, Richards, Renee S., Gartside, Michael, Patel, Kalpana, Clemons, Nicholas J., Phillips, Wayne A., Barbour, Andrew, Westerhuis, Johan A. and Hill, Michelle M. (2022). Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid‐induced DNA damage. Clinical and Translational Medicine, 12 (5) e810, 1-19. doi: 10.1002/ctm2.810
ctDNA as a biomarker of progression in oesophageal adenocarcinoma
Bonazzi, V. F., Aoude, L. G., Brosda, S., Lonie, J. M., Patel, K., Bradford, J. J., Koufariotis, L. T., Wood, S., Smithers, B. Mark, Waddell, N. and Barbour, A. P. (2022). ctDNA as a biomarker of progression in oesophageal adenocarcinoma. ESMO Open, 7 (3) 100452, 100452. doi: 10.1016/j.esmoop.2022.100452
Mercieca-Bebber, R., Barnes, E. H., Wilson, K., Samoon, Z., Walpole, E., Mai, T., Ackland, S., Burge, M., Dickie, G., Watson, D., Leung, J., Wang, T., Bohmer, R., Cameron, D., Simes, J., Gebski, V., Smithers, M., Thomas, J., Zalcberg, J. and Barbour, A. P. (2022). Patient-reported outcome (PRO) results from the AGITG DOCTOR trial: a randomised phase 2 trial of tailored neoadjuvant therapy for resectable oesophageal adenocarcinoma. BMC Cancer, 22 (1) 276, 1-11. doi: 10.1186/s12885-022-09270-4
Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul and Hill, Michelle M. (2022). C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma. Frontiers in Immunology, 13 842023, 842023. doi: 10.3389/fimmu.2022.842023
van der Wilk, Berend J., Hagens, Eliza R. C., Eyck, Ben M., Gisbertz, Suzanne S., van Hillegersberg, Richard, Nafteux, Philippe, Schröder, Wolfgang, Nilsson, Magnus, Wijnhoven, Bas P. L., Lagarde, Sjoerd M., van Berge Henegouwen, Mark I., International Esodata Study Group Collaborators , Smithers, Mark, Thomson, Iain, Barbour, Andrew and Thomas, Janine (2022). Outcomes after totally minimally invasive versus hybrid and open Ivor Lewis oesophagectomy: results from the International Esodata Study Group. British Journal of Surgery, 109 (3), 283-290. doi: 10.1093/bjs/znab432
Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence
Dreyer, Stephan B., Upstill-Goddard, Rosie, Legrini, Assya, Biankin, Andrew V., Allison, Sarah, Beraldi, Dario, Cameron, Euan, Chang, David K., Cooke, Susanna L., Cunningham, Richard, Dreyer, Stephan, Grimwood, Paul, Kelly, Shane, Marshall, John, McDade, Brian, Musgrove, Elizabeth A., Ramsay, Donna, Evers, Lisa, Rebus, Selma, Rahib, Lola, Serrels, Bryan, Jamieson, Nigel B., McKay, Colin J., Westwood, Paul, Williams, Nicola, Duthie, Fraser, Shen, William, Pea, Antonio, Johns, Amber L. ... Bassi, Claudio (2022). Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence. Gastroenterology, 162 (1), 320-324. doi: 10.1053/j.gastro.2021.09.022
Oar, Andrew, Lee, Mark, Le, Hien, Wilson, Kate, Aiken, Chris, Chantrill, Lorraine, Simes, John, Nguyen, Nam, Barbour, Andrew, Samra, Jaswinder, Sjoquist, Katrin M., Moore, Alisha, Espinoza, David, Gebski, Val, Yip, Sonia, Chu, Julie, Kneebone, Andrew and Goldstein, David (2021). AGITG MASTERPLAN: a randomised phase II study of modified FOLFIRINOX alone or in combination with stereotactic body radiotherapy for patients with high-risk and locally advanced pancreatic cancer. BMC Cancer, 21 (1) 936. doi: 10.1186/s12885-021-08666-y
Lakis, Vanessa, Lawlor, Rita T., Newell, Felicity, Patch, Ann-Marie, Mafficini, Andrea, Sadanandam, Anguraj, Koufariotis, Lambros T., Johnston, Rebecca L., Leonard, Conrad, Wood, Scott, Rusev, Borislav, Corbo, Vincenzo, Luchini, Claudio, Cingarlini, Sara, Landoni, Luca, Salvia, Roberto, Milella, Michele, Chang, David, Bailey, Peter, Jamieson, Nigel B., Duthie, Fraser, Gingras, Marie-Claude, Muzny, Donna M., Wheeler, David A., Gibbs, Richard A., Milione, Massimo, Chantrill, Lorraine A., Timpson, Paul, Chou, Angela ... Scarpa, Aldo (2021). DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association. Communications Biology, 4 (1) 155, 1-11. doi: 10.1038/s42003-020-01469-0
ROR1 and ROR2 expression in pancreatic cancer
Liu, Dongli, Sharbeen, George, Phillips, Phoebe, Johns, Amber L., Gill, Anthony J., Chantrill, Lorraine A., Timpson, Paul, Chou, Angela, Pajic, Marina, Dwarte, Tanya, Herrmann, David, Vennin, Claire, Cox, Thomas R., Pereira, Brooke, Ritchie, Shona, Reed, Daniel A., Chambers, Cecilia R., Metcalf, Xanthe, Nobis, Max, Waddell, Nicola, Pearson, John V., Patch, Ann-Marie, Nones, Katia, Newell, Felicity, Mukhopadhyay, Pamela, Addala, Venkateswar, Kazakoff, Stephen, Holmes, Oliver, Leonard, Conrad ... Ford, Caroline E. (2021). ROR1 and ROR2 expression in pancreatic cancer. BMC Cancer, 21 (1) 1199. doi: 10.1186/s12885-021-08952-9
Bulamu, Norma B., Vissapragada, Ravi, Chen, Gang, Ratcliffe, Julie, Mudge, Louise A., Smithers, B. Mark, Isenring, Elizabeth A., Smith, Lorelle, Jamieson, Glyn G., Watson, David I., Bessell, Justin, Barbour, Andrew, Aly, Ahmad, Archer, Stephen, Ballal, Mohammed, Barbon, Jessica, Benton, Katie, Bond, Melissa, Berryman, Melissa, Bright, Tim, Cade, Richard, Cardamis, Anna, Carroll, Rosemary, Cashman, Kara, Chan, Larissa, Chapman, Brooke, Chapman, Sally, Chen, Derek, Chisholm, Jacob ... on behalf of The Australian Immunonutrition Study Group (2021). Responsiveness and convergent validity of QLU-C10D and EQ-5D-3L in assessing short-term quality of life following esophagectomy. Health and Quality of Life Outcomes, 19 (1) 233, 1-11. doi: 10.1186/s12955-021-01867-w
Wang, Jing, Wuethrich, Alain, Lobb, Richard J., Antaw, Fiach, Sina, Abu Ali Ibn, Lane, Rebecca E., Zhou, Quan, Zieschank, Chloe, Bell, Caroline, Bonazzi, Vanessa F., Aoude, Lauren G., Everitt, Sarah, Yeo, Belinda, Barbour, Andrew P., Möller, Andreas and Trau, Matt (2021). Characterizing the heterogeneity of small extracellular vesicle populations in multiple cancer types via an ultrasensitive chip. ACS Sensors, 6 (9) acssensors.1c00358, 3182-3194. doi: 10.1021/acssensors.1c00358
Lonie, James M., Barbour, Andrew P. and Dolcetti, Riccardo (2021). Understanding the immuno-biology of oesophageal adenocarcinoma: towards improved therapeutic approaches. Cancer Treatment Reviews, 98 102219, 1-13. doi: 10.1016/j.ctrv.2021.102219
Aoude, Lauren G., Wong, Bernadette, Bonazzi, Vanessa F, Brosda, Sandra, Walters, Shaun B., Koufariotis, Lambros T., Naeini, Marjan M., Pearson, John V, Oey, Harald, Patel, Kalpana, Bradford, Julia J., Bloxham, Conor J, Atkinson, Victoria, Law, Phillip, Strutton, Geoffrey, Bayley, Gerard, Yang, Samuel, Smithers, B. Mark, Waddell, Nicola, Miles, Kenneth and Barbour, Andrew P. (2021). Radiomics biomarkers correlate with CD8 expression and predict immune signatures in melanoma patients. Molecular Cancer Research, 19 (6) molcanres.1038.2020, 950-956. doi: 10.1158/1541-7786.mcr-20-1038
Lee, Yoke Seng, O'Brien, Liam J., Walpole, Carina M., Pearson, Frances E., Leal-Rojas, Ingrid M., Masterman, Kelly-Anne, Atkinson, Victoria, Barbour, Andrew and Radford, Kristen J. (2021). Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model. Journal for ImmunoTherapy of Cancer, 9 (3) e001963, 1-12. doi: 10.1136/jitc-2020-001963
Complications and survival after hybrid and fully minimally invasive oesophagectomy
Veenstra, M. M. K., Smithers, B. M., Visser, E., Edholm, D., Brosda, S., Thomas, J. M., Gotley, D. C., Thomson, I. G., Wijnhoven, B. P. L. and Barbour, A. P. (2021). Complications and survival after hybrid and fully minimally invasive oesophagectomy. BJS Open, 5 (1) zraa033, 1-7. doi: 10.1093/bjsopen/zraa033
Targeting DNA damage response and replication stress in pancreatic cancer
Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc D., Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L. ... Sansom, Owen J. (2021). Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160 (1), 362-377.e13. doi: 10.1053/j.gastro.2020.09.043
Na, Renhua, Miura, Kyoko, O’Brien, Suzanne, Eslick, Guy D., Kendall, Bradley J., Hourigan, Luke F., Bourke, Michael, Cox, Michael R., Farrokhzadi, Laal, Levert-Mignon, Angelique J., Barbour, Andrew P., Clemons, Nicholas J., Duong, Cuong P., Lord, Reginald V., Phillips, Wayne A., Watson, David I. and Whiteman, David C. (2020). Clinical pathways and outcomes of patients with Barrett’s esophagus in tertiary care settings: a prospective longitudinal cohort study in Australia, 2008–2016. Diseases of the Esophagus, 34 (8) doaa119. doi: 10.1093/dote/doaa119
Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Jiao, Wei, Kaiser, Vera B., Karlic, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N. ... von Mering, Christian (2020). A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature Communications, 11 (1) 728. doi: 10.1038/s41467-019-13825-8
Bailey, Matthew H., Meyerson, William U., Dursi, Lewis Jonathan, Wang, Liang-Bo, Dong, Guanlan, Liang, Wen-Wei, Weerasinghe, Amila, Li, Shantao, Li, Yize, Kelso, Sean, Akbani, Rehan, Anur, Pavana, Bailey, Matthew H., Buchanan, Alex, Chiotti, Kami, Covington, Kyle, Creason, Allison, Ding, Li, Ellrott, Kyle, Fan, Yu, Foltz, Steven, Getz, Gad, Hale, Walker, Haussler, David, Hess, Julian M., Hutter, Carolyn M., Kandoth, Cyriac, Kasaian, Katayoon, Kasapi, Melpomeni ... von Mering, Christian (2020). Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y). Nature Communications, 11 (1) 6232. doi: 10.1038/s41467-020-20128-w
Divergent mutational processes distinguish hypoxic and normoxic tumours
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Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
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Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
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Sex differences in oncogenic mutational processes
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Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients
Aoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola and Barbour, Andrew P. (2020). Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients. Scientific Reports, 10 (1) 17687, 17687. doi: 10.1038/s41598-020-74956-3
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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer
Brunton, Holly, Caligiuri, Giuseppina, Cunningham, Richard, Upstill-Goddard, Rosie, Bailey, Ulla-Maja, Garner, Ian M., Nourse, Craig, Dreyer, Stephan, Jones, Marc, Moran-Jones, Kim, Wright, Derek W., Paulus-Hock, Viola, Nixon, Colin, Thomson, Gemma, Jamieson, Nigel B., McGregor, Grant A., Evers, Lisa, McKay, Colin J., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephen J., Dziubinski, Michele L., Barry, Simon T., Grützmann, Robert, Brown, Robert, Curry, Edward, Allison, Sarah, Biankin, Andrew V. ... Australian Pancreatic Cancer Genome Initiative (2020). HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer. Cell Reports, 31 (6) 107625, 1-28. doi: 10.1016/j.celrep.2020.107625
Oar, Andrew, Lee, Mark, Le, Hien, Hruby, George, Dalfsen, Raymond, Pryor, David, Lee, Dominique, Chu, Julie, Holloway, Lois, Briggs, Adam, Barbour, Andrew, Chander, Sarat, Ng, Sweet Ping, Samra, Jas, Shakeshaft, John, Goldstein, David, Nguyen, Nam, Goodman, Karyn A., Chang, Daniel T. and Kneebone, Andrew (2020). Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) guidelines for pancreatic stereotactic body radiation therapy (SBRT). Practical Radiation Oncology, 10 (3), e136-e146. doi: 10.1016/j.prro.2019.07.018
Roy, Amitesh C., Shapiro, Jeremy, Burge, Matt, Karapetis, Christos S., Pavlakis, Nick, Segelov, Eva, Chau, Ian, Lordick, Florian, Chen, Li-Tong, Barbour, Andrew, Tebbutt, Niall and Price, Tim (2020). Management of early-stage gastro-esophageal cancers: expert perspectives from the Australasian Gastrointestinal Trials Group (AGITG) with invited international faculty. Expert Review of Anticancer Therapy, 20 (4), 305-324. doi: 10.1080/14737140.2020.1746185
Teras, Jüri, Kroon, Hidde M., Miura, John T., Kenyon-Smith, Tim, Beasley, Georgia M., Mullen, Dean, Farrow, Norma E., Mosca, Paul J., Lowe, Michael C., Farley, Clara R., Potdar, Aishwarya, Daou, Hala, Sun, James, Carr, Michael, Farma, Jeffrey M., Henderson, Michael A., Speakman, David, Serpell, Jonathan, Delman, Keith A., Smithers, B. Mark, Barbour, Andrew, Tyler, Douglas S., Coventry, Brendon J., Zager, Jonathan S. and Thompson, John F. (2020). International multicenter experience of isolated limb infusion for in-transit melanoma metastases in octogenarian and nonagenarian patients. Annals of Surgical Oncology, 27 (5), 1420-1429. doi: 10.1245/s10434-020-08312-0
Pan-cancer analysis of whole genomes
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Barbour, A P, Walpole, E T, Mai, G T, Barnes, E H, Watson, D I, Ackland, S P, Martin, J M, Burge, M, Finch, R, Karapetis, C S, Shannon, J, Nott, L M, Varma, S, Marx, G, Falk, G L, Gebski, V, Oostendorp, M, Wilson, K, Thomas, J, Lampe, G, Zalcberg, J R, Simes, J, Smithers, B M and DOCTOR investigators (2020). Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phase II trial. Annals of Oncology, 31 (2), 236-245. doi: 10.1016/j.annonc.2019.10.019
Barbour, Andrew P., Samra, Jaswinder S., Haghighi, Koroush S., Donoghoe, Mark W., Burge, Matthew, Harris, Marion T., Chua, Yu Jo, Mitchell, Jenna, O’Rourke, Nick, Chan, Howard, Gebski, Val J., Gananadha, Sivakumar, Croagh, Daniel G., Kench, James G., Goldstein, David, Barbour, A., Goldstein, D., Samra, J. S., Harris, M., Chua, Y. J., O’Rourke, N., Yip, S., Gebski, V., Simes, J., Hicks, R., Coates, A., Gurney, H., Do, V., Marschner, I. ... Jones, R. (2020). The AGITG GAP study: a phase II study of perioperative gemcitabine and nab-paclitaxel for resectable pancreas cancer. Annals of Surgical Oncology, 27 (7), 2506-2515. doi: 10.1245/s10434-020-08205-2
Kryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A., Tse, Brian W.C., Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I., Quigley, James P., Law, Ruby H.P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu and Hooper, John D. (2020). Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma. Theranostics, 10 (9), 4116-4133. doi: 10.7150/thno.43589
van Hootegem, S. J. M., Smithers, B. M., Gotley, D. C., Brosda, S., Thomson, I. G., Thomas, J. M., Gartside, M. and Barbour, A. P. (2019). Baseline neutrophil–lymphocyte ratio holds no prognostic value for esophageal and junctional adenocarcinoma in patients treated with neoadjuvant chemotherapy. Diseases of the Esophagus, 33 (6). doi: 10.1093/dote/doz082
van Hootegem, Sander J. M., Smithers, B. Mark, Gotley, David C., Brosda, Sandra, Thomson, Iain G., Thomas, Janine M., Gartside, Michael, van Lanschot, Jan J. B., Lagarde, Sjoerd M., Wijnhoven, Bas P. L. and Barbour, Andrew P. (2019). The impact of signet ring cell differentiation on outcome in patients with esophageal and gastroesophageal junction adenocarcinoma. Annals of Surgical Oncology, 26 (8), 2375-2384. doi: 10.1245/s10434-019-07322-x
Vennin, Claire, Melenec, Pauline, Rouet, Romain, Nobis, Max, Cazet, Aurelie S., Murphy, Kendelle J., Herrmann, David, Reed, Daniel A., Lucas, Morghan C., Warren, Sean C., Elgundi, Zehra, Pinese, Mark, Kalna, Gabriella, Roden, Daniel, Samuel, Monisha, Zaratzian, Anaiis, Grey, Shane T., Da Silva, Andrew, Leung, Wilfred, Mathivanan, Suresh, Wang, Yingxiao, Braithwaite, Anthony W., Christ, Daniel, Benda, Ales, Parkin, Ashleigh, Phillips, Phoebe A., Whitelock, John M., Gill, Anthony J., Sansom, Owen J. ... Australian Pancreatic Genome Initiative (APGI) (2019). CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan. Nature Communications, 10 (1) 3637. doi: 10.1038/s41467-019-10968-6
Kroon, Hidde M., Coventry, Brendon J., Henderson, Michael A., Barbour, Andrew, Serpell, Jonathan, Smithers, B. Mark and Thompson, John F. (2019). Evaluation of the efficacy and toxicity of upper extremity isolated limb infusion chemotherapy for melanoma: an Australian multi-center study. European Journal of Surgical Oncology, 45 (5), 832-837. doi: 10.1016/j.ejso.2019.02.026
To be or not to be: Non-invasive screening for Barrett’s esophagus, dysplasia and adenocarcinoma
Shah, Alok K., Joshi, Virendra, Hartel, Gunter, Barbour, Andrew P. and Hill, Michelle M. (2019). To be or not to be: Non-invasive screening for Barrett’s esophagus, dysplasia and adenocarcinoma. Translational Gastroenterology and Hepatology, 4 (May) 31, 31-31. doi: 10.21037/tgh.2019.04.08
Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples
Newell, Felicity, Patel, Kalpana, Gartside, Michael, Krause, Lutz, Brosda, Sandra, Aoude, Lauren G., Loffler, Kelly A., Bonazzi, Vanessa F., Patch, Ann-Marie, Kazakoff, Stephen H., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Lampe, Guy, Lord, Reginald V., Whiteman, David C., Pearson, John V., Nones, Katia, Waddell, Nicola and Barbour, Andrew P. (2019). Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples. BMC Medical Genomics, 12 (1) 31, 31. doi: 10.1186/s12920-019-0476-9
Read, Tavis, Fayers, Warren, Thomas, Janine, Wagels, Michael, Barbour, Andrew and Smithers, B. Mark (2019). Patients with in-transit melanoma metastases have comparable survival outcomes following isolated limb infusion or intralesional PV-10-A propensity score matched, single center study. Journal of Surgical Oncology, 119 (6), 717-727. doi: 10.1002/jso.25373
Shah, Alok K., Hartel, Gunter, Brown, Ian, Winterford, Clay, Na, Renhua, Lê Cao, Kim-Anh, Spicer, Bradley A., Dunstone, Michelle A., Phillips, Wayne A, Lord, Reginald V., Barbour, Andrew P., Watson, David I., Joshi, Virendra, Whiteman, David C. and Hill, Michelle M. (2018). Evaluation of serum glycoprotein biomarker candidates for detection of esophageal adenocarcinoma and surveillance of Barrett’s esophagus. Molecular and Cellular Proteomics, 17 (12), 2324-2334. doi: 10.1074/mcp.ra118.000734
Effeney, R., Shaw, T., Burmeister, B. H., Burmeister, E., Harvey, J., Mai, G. T., Thomas, J., Barbour, A. P., Smithers, B. M. and Pryor, D. I. (2018). Patterns of failure following dose-escalated chemoradiotherapy for fluorodeoxyglucose positron emission tomography staged squamous cell carcinoma of the oesophagus. Clinical Oncology, 30 (10), 642-649. doi: 10.1016/j.clon.2018.06.011
Neoadjuvant chemotherapy or chemoradiotherapy for adenocarcinoma of the esophagus
Visser, Els, Edholm, David, Smithers, B. Mark, Thomson, Iain G., Burmeister, Bryan H., Walpole, Euan T., Gotley, David C., Joubert, Warren L., Atkinson, Victoria, Mai, Tao, Thomas, Janine M. and Barbour, Andrew P. (2018). Neoadjuvant chemotherapy or chemoradiotherapy for adenocarcinoma of the esophagus. Journal of Surgical Oncology, 117 (8), 1687-1696. doi: 10.1002/jso.25089
Neoadjuvant therapy reduces cardiopulmunary function in patients undegoing oesophagectomy
Thomson, Iain G., Wallen, Matthew P., Hall, Adrian, Ferris, Rebekah, Gotley, David C., Barbour, Andrew P., Lee, Andrew, Thomas, Janine and Smithers, Bernard M. (2018). Neoadjuvant therapy reduces cardiopulmunary function in patients undegoing oesophagectomy. International Journal of Surgery, 53, 86-92. doi: 10.1016/j.ijsu.2018.03.030
Read, Tavis A., Smith, Aaron, Thomas, Janine, David, Michael, Foote, Matthew, Wagels, Michael, Barbour, Andrew and Smithers, B. Mark (2018). Intralesional PV-10 for the treatment of in-transit melanoma metastases-Results of a prospective, non-randomized, single center study. Journal of Surgical Oncology, 117 (4), 579-587. doi: 10.1002/jso.24921
Breaking bad conduits: 'resleeving' the intrathoracic gastric conduit post oesophagectomy
Evennett, Nicholas J. and Barbour, Andrew P. (2018). Breaking bad conduits: 'resleeving' the intrathoracic gastric conduit post oesophagectomy. ANZ Journal of Surgery, 88 (3), E222-E223. doi: 10.1111/ans.13337
Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma
Nepal, Chirag, O'Rourke, Colm J., Oliveira, Douglas Vnp, Taranta, Andrzej, Shema, Steven, Gautam, Prson, Calderaro, Julien, Barbour, Andrew, Raggi, Chiara, Wennerberg, Krister, Wang, Xin W., Lautem, Anja, Roberts, Lewis R. and Andersen, Jesper B. (2017). Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma. Hepatology (Baltimore, Md.), 68 (3), 949-963. doi: 10.1002/hep.29764
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
Balachandran, Vinod P., Łuksza, Marta, Zhao, Julia N., Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umesh, Senbabaoglu, Yasin, Wells, Daniel K., Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Larkin Kelley, Z., Basturk, Olca, Gönen, Mithat, Levine, Arnold J., Allen, Peter J., Fearon, Douglas T., Merad, Miriam ... Bassi, Claudio (2017). Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. Nature, 551 (7681), 512-516. doi: 10.1038/nature24462
Kroon, Hidde M., Coventry, Brendon J., Giles, Mitchell H., Henderson, Michael A., Speakman, David, Wall, Mark, Barbour, Andrew, Serpell, Jonathan, Paddle, Paul, Smithers, Bernard M. and Thompson, John F. (2017). Safety and Efficacy of Isolated Limb Infusion Chemotherapy for Advanced Locoregional Melanoma in Elderly Patients: An Australian Multicenter Study. Annals of Surgical Oncology, 24 (11), 3245-3251. doi: 10.1245/s10434-017-6046-5
Gyorki, David E., Barbour, Andrew, Hanikeri, Mark, Mar, Victoria, Sandhu, Shahneen and Thompson, John F. (2017). When is a sentinel node biopsy indicated for patients with primary melanoma? An update of the 'Australian guidelines for the management of cutaneous melanoma'. Australasian Journal of Dermatology, 58 (4), 274-277. doi: 10.1111/ajd.12662
Primary cutaneous melanoma of the scalp: Patterns of recurrence
Sparks, David S., Read, Tavis, Lonne, Michael, Barbour, Andrew P., Wagels, Michael, Bayley, Gerard J. and Smithers, B. Mark (2017). Primary cutaneous melanoma of the scalp: Patterns of recurrence. Journal of Surgical Oncology, 115 (4), 449-454. doi: 10.1002/jso.24535
Whole-genome landscape of pancreatic neuroendocrine tumours
Scarpa, Aldo, Chang, David K., Nones, Katia, Corbo, Vincenzo, Patch, Ann-Marie, Bailey, Peter, Lawlor, Rita T., Johns, Amber L., Miller, David K., Mafficini, Andrea, Rusev, Borislav, Scardoni, Maria, Antonello, Davide, Barbi, Stefano, Sikora, Katarzyna O., Cingarlini, Sara, Vicentini, Caterina, McKay, Skye, Quinn, Michael C.J., Bruxner, Timothy J.C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, McLean, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wilson, Peter J., Anderson, Matthew J., Fink, J. Lynn ... Grimmond, Sean M. (2017). Whole-genome landscape of pancreatic neuroendocrine tumours. Nature, 543 (7643), 65-71. doi: 10.1038/nature21063
Secrier, Maria, Li, Xiaodun, de Silva, Nadeera, Eldridge, Matthew D., Contino, Gianmarco, Bornschein, Jan, MacRae, Shona, Grehan, Nicola, O'Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P., Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A W, Lynch, Andy G., Tavaré, Simon and Fitzgerald, Rebecca C. (2017). Corrigendum: Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance. Nature Genetics, 49 (2), 317-317. doi: 10.1038/ng0217-317a
Hypermutation in pancreatic cancer
Humphris, Jeremy L., Patch, Ann-Marie, Nones, Katia, Bailey, Peter J., Johns, Amber L., McKay, Skye, Chang, David K., Miller, David K., Pajic, Marina, Kassahn, Karin S., Quinn, Michael C. J., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Stone, Andrew, Wilson, Peter J., Anderson, Matthew, Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Mead, Ronald S. ... Biankin, Andrew V. (2017). Hypermutation in pancreatic cancer. Gastroenterology, 152 (1), 68-74.e2. doi: 10.1053/j.gastro.2016.09.060
Krause, Lutz, Nones, Katia , Loffler, Kelly A., Nancarrow, Derek, Oey, Harald , Tang, Yue Hang, Wayte, Nicola J., Patch, Ann Marie, Patel, Kalpana , Brosda, Sandra, Manning, Suzanne, Lampe, Guy, Clouston, Andrew, Thomas, Janine, Stoye, Jens, Hussey, Damian J., Watson, David I., Lord, Reginald V., Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Grimmond, Sean M., Waddell, Nicola and Barbour, Andrew P. (2016). Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis, 37 (4), 356-365. doi: 10.1093/carcin/bgw018
Secrier, Maria, Li, Xiaodun, De Silva, Nadeera, Eldridge, Matthew D., Contino, Gianmarco, Bornschein, Jan, Macrae, Shona, Grehan, Nicola, O'Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P., Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A. W., Lynch, Andy G., Tavare, Simon, Fitzgerald, Rebecca C., Noorani, Ayesha, Elliott, Rachael Fels, Weaver, Jamie ... Grimmond, Sean M. (2016). Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance. Nature Genetics, 48 (10), 1131-1141. doi: 10.1038/ng.3659
Rowe, Casey J., Tang, Fiona, Hughes, Maria Celia B., Rodero, Mathieu P., Malt, Maryrose, Lambie, Duncan, Barbour, Andrew, Hayward, Nicholas K., Smithers, B. Mark, Green, Adele C. and Khosrotehrani, Kiarash (2016). Molecular markers to complement sentinel node status in predicting survival in patients with high-risk locally invasive melanoma. International Journal of Cancer, 139 (3), 664-672. doi: 10.1002/ijc.30085
Refining the care of patients with pancreatic cancer: the AGITG pancreatic cancer workshop consensus
Gandy, Robert C., Barbour, Andrew P., Samra, Jaswinder, Nikfarjam, Mehrdad, Haghighi, Koroush, Kench, James G., Saxena, Payal and Goldstein, David (2016). Refining the care of patients with pancreatic cancer: the AGITG pancreatic cancer workshop consensus. Medical Journal of Australia, 204 (11), 419-422. doi: 10.5694/mja16.00061
Shah, Alok K., Le Cao, Kim-Anh, Choi, Eunju, Chen, David, Gautier, Benoit, Nancarrow, Derek, Whiteman, David C., Baker, Peter R., Clauser, Karl R., Chalkley, Robert J., Saunders, Nicholas A., Barbour, Andrew P., Joshi, Virendra and Hill, Michelle M. (2016). Glyco-centric lectin magnetic bead array (LeMBA) - proteomics dataset of human serum samples from healthy, Barrett's esophagus and esophageal adenocarcinoma individuals. Data in Brief, 7, 1058-1062. doi: 10.1016/j.dib.2016.03.081
Theodore, Jane E., Frankel, Adam J., Thomas, Janine M., Barbour, Andrew P., Bayley, Gerard J., Allan, Christopher P., Wagels, Michael and Smithers, B. Mark (2016). Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma. ANZ journal of surgery, 87 (1-2), 44-48. doi: 10.1111/ans.13526
Australian multicenter study of isolated limb infusion for melanoma
Kroon, Hidde M., Coventry, Brendon J., Giles, Mitchell H., Henderson, Michael A., Speakman, David, Wall, Mark, Barbour, Andrew, Serpell, Jonathan, Paddle, Paul, Coventry, Alexander G. J., Sullivan, Thomas, Smithers, Bernard Mark and Thompson, John F. (2016). Australian multicenter study of isolated limb infusion for melanoma. Annals of Surgical Oncology, 23 (4), 1096-1103. doi: 10.1245/s10434-015-4969-2
Genomic analyses identify molecular subtypes of pancreatic cancer
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Genomics of pancreatic tumours - what we now know
Patch, Ann-Marie, Barbour, Andrew and Waddell, Nicola (2016). Genomics of pancreatic tumours - what we now know. Cancer Forum, 40 (1), 6-10.
Pancreatic cancer: is the surgeon still relevant?
Butler, Nick, Samra, Jaswinder, Nikfarjam, Mehrdad and Barbour, Andrew P. (2016). Pancreatic cancer: is the surgeon still relevant?. Cancer Forum, 40 (1), 39-42.
Sentinel node biopsy in patients with intermediate and thick melanomas - A balanced view
Saw, Robyn, Allan, Christopher, Barbour, Andrew, Ch'ng, Sydney, Coventry, Brendon J., Gyorki, David, Henderson, Michael, Howle, Julie, Hughes, T. Michael, Lee, Kenneth, Neuhaus, Susan, Saunders, Christobel, Shannon, Kerwin, Smithers, Mark, Speakman, David, Spillane, John and Stretch, Jonathan (2015). Sentinel node biopsy in patients with intermediate and thick melanomas - A balanced view. Australian Family Physician, 44 (12), 876-876.
Meta-analysis of radical resection rates and margin assessment in pancreatic cancer
Chandrasegaram, M. D., Goldstein, D., Simes, J., Gebski, V., Kench, J. G., Gill, A. J., Samra, J. S., Merrett, N. D., Richardson, A. J. and Barbour, A. P. (2015). Meta-analysis of radical resection rates and margin assessment in pancreatic cancer. British Journal of Surgery, 102 (12), 1459-1472. doi: 10.1002/bjs.9892
Shah, Alok K., Le Cao, Kim-Anh, Choi, Eunju, Chen, David, Gautier, Benoit, Nancarrow, Derek, Whiteman, David C., Saunders, Nicholas A., Barbour, Andrew P., Joshi, Virendra and Hill, Michelle M. (2015). Serum glycoprotein biomarker discovery and qualification pipeline reveals novel diagnostic biomarker candidates for esophageal adenocarcinoma. Molecular and Cellular Proteomics, 14 (11), 3023-3039. doi: 10.1074/mcp.M115.050922
Smithers, B.Mark, Hughes, Maria Celia B., Beesley, Vanessa L., Barbour, Andrew P., Malt, Maryrose K., Weedon, David, Zonta, Mark J., Wood, Dominic J., Triscott, Joseph A., Bayley, Gerard J., Brown, Lee J., Allan, Christopher P., D'Arcy, Justin, Williamson, Richard, Khosrotehrani, Kiarash and Green, Adele C. (2015). Prospective study of patterns of surgical management in adults with primary cutaneous melanoma at high risk of spread, in Queensland, Australia. Journal of Surgical Oncology, 112 (4), 359-365. doi: 10.1002/jso.24013
Two cases of NSAID-induced gastropathy and enteropathy of the ileum
Auld, Michael C., Dodd, Benjamin R., Barbour, Andrew P. and Smithers, Mark (2015). Two cases of NSAID-induced gastropathy and enteropathy of the ileum. ANZ Journal of Surgery, 85 (7-8), 584-585. doi: 10.1111/ans.12462
Tembe, Varsha, Schramm, Sarah-Jane, Stark, Mitchell, Patrick, Ellis, Jayaswal, Vivek, Tang, Yue Hang, Barbour, Andrew, Hayward, Nicholas K., Thompson, John F., Scolyer, Richard A., Yang, Yee Hwa and Mann, Graham J. (2015). MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis. Pigment Cell and Melanoma Research, 28 (3), 254-266. doi: 10.1111/pcmr.12343
Stark, Mitchell S., Klein, Kerenaftali, Weide, Benjamin, Haydu, Lauren E., Pflugfelder, Annette, Tang, Yue Hang, Palmer, Jane M., Whiteman, David C., Scolyer, Richard A., Mann, Graham J., Thompson, John F., Long, Georgina V., Barbour, Andrew P., Soyer, H. Peter, Garbe, Claus, Herington, Adrian, Pollock, Pamela M. and Hayward, Nicholas K. (2015). The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis. EBioMedicine, 2 (7), 671-680. doi: 10.1016/j.ebiom.2015.05.011
Whole genomes redefine the mutational landscape of pancreatic cancer
Waddell, Nicola, Pajic, Marina, Patch, Anne-Marie, Chang, David K, Kassahn, Karin S, Bailey, Peter, Johns, Amber L, Miller, David, Nones, Katia, Quek, Kelly, Quinn, Michael C. J, Robertson, Alan J, Fadlullah, Muhammad Z.H, Bruxner, Tim J.C, Christ, Angelika N, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Wilson, Peter J, Markham, Emma, Cloonan, Nicole, Anderson, Matthew J, Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen H, Leonard, Conrad ... Grimmond, Sean M (2015). Whole genomes redefine the mutational landscape of pancreatic cancer. Nature, 518 (7540), 495-501. doi: 10.1038/nature14169
Barbour, Samantha, Smithers, B. Mark, Allan, Chris, Bayley, Gerard, Thomas, Janine, Foote, Matthew, Burmeister, Bryan and Barbour, Andrew P. (2015). Patterns of recurrence in patients with stage IIIB/C cutaneous melanoma of the head and neck following surgery with and without adjuvant radiation therapy: is isolated regional recurrence salvageable?. Annals of Surgical Oncology, 22 (12), 4052-4059. doi: 10.1245/s10434-014-4356-4
Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis
Nones, Katia, Waddell, Nicola, Wayte, Nicci, Patch, Ann-Marie, Bailey, Peter, Newell, Felicity, Holmes, Oliver, Fink, J. Lynn, Quinn, Michael C. J., Tang, Yue Hang, Lampe, Guy, Quek, Kelly, Loffler, Kelly A., Manning, Suzanne, Idrisoglu, Senel, Miller, David, Xu, Qinying, Waddell, Nick, Wilson, Peter J., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Anderson, Matthew, Kazakoff, Stephen, Leonard, Conrad, Wood, Scott, Simpson, Peter T. ... Barbour, Andrew P. (2014). Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis. Nature Communications, 5 (1) 6224, 5224.1-5224.9. doi: 10.1038/ncomms6224
Beesley, Vanessa L., Smithers, B. Mark, Khosrotehrani, Kiarash, Khatun, Modsina, O'Rourke, Peter, Hughes, Maria Celia B., Malt, Maryrose K., Zonta, Mark J., Bayley, Gerard J., Barbour, Andrew P., Brown, Lee J., D'Arcy, Justin, Allan, Christopher and Green, Adèle C. (2014). Supportive care needs, anxiety, depression and quality of life amongst newly diagnosed patients with localised invasive cutaneous melanoma in Queensland, Australia. Psycho-Oncology, 24 (7), 763-770. doi: 10.1002/pon.3718
Barbour, Andrew P., Tang, Yue Hang, Armour, Nicola, Dutton-Regester, Ken, Krause, Lutz, Loffler, Kelly A., Lambie, Duncan, Burmeister, Bryan, Thomas, Janine, Smithers, B. Mark and Hayward, Nicholas K. (2014). BRAF mutation status is an independent prognostic factor for resected stage IIIB and IIIC melanoma: implications for melanoma staging and adjuvant therapy. European Journal of Cancer, 50 (15), 2668-2676. doi: 10.1016/j.ejca.2014.06.009
Controversies in the management of gastrointestinal stromal tumors
Yip, Desmond, Zalcberg, John, Ackland, Stephen, Barbour, Andrew P., Desai, Jayesh, Fox, Stephen, Kotasek, Dusan, McArthur, Grant and Smithers, B. Mark (2014). Controversies in the management of gastrointestinal stromal tumors. Asia-Pacific Journal of Clinical Oncology, 10 (3), 216-227. doi: 10.1111/ajco.12187
Coventry, Brendon J., Kroon, Hidde M., Giles, Mitchell H., Henderson, Michael, Speakman, David, Wall, Mark, Barbour, Andrew, Serpell, Jonathan, Paddle, Paul, Coventry, Alexander G.J., Sullivan, Thomas and Smithers, B. Mark (2014). Australian multi-center experience outside of the Sydney Melanoma Unit of isolated limb infusion chemotherapy for melanoma. Journal of Surgical Oncology, 109 (8), 780-785. doi: 10.1002/jso.23590
Khosrotehrani, Kiarash, van der Ploeg, Augustinus P.T., Siskind,Victor, Hughes, Maria Celia, Wright, Annaliesa, Thomas, Janine, Barbour, Andrew, Allan, Christopher, Bayley, Gerard, Eggermont, Alexander, Verhoef, Cornelis, Smithers, B. Mark and Green, Adele C. (2014). Nomograms to predict recurrence and survival in stage IIIB and IIIC melanoma after therapeutic lymphadenectomy. European Journal of Cancer, 50 (7), 1301-1309. doi: 10.1016/j.ejca.2014.02.010
Frankel, Adam, Armour, Nicola, Nancarrow, Derek, Krause, Lutz, Hayward, Nicholas, Lampe, Guy, Smithers, B. Mark and Barbour, Andrew (2014). Genome-wide analysis of esophageal adenocarcinoma yields specific copy number aberrations that correlate with prognosis. Genes Chromosomes and Cancer, 53 (4), 324-338. doi: 10.1002/gcc.22143
Liyanage, Surabhi S., Segelov, Eva, Malik, Aisha, Garland, Suzanne M., Tabrizi, Sepehr N., Cummins, Eleanor, Seale, Holly, Rahman, Bayzidur, Moa, Aye, Barbour, Andrew P., Crowe, Philip J. and Macintyre, C. Raina (2014). A case-control study of the role of human papillomavirus in oesophageal squamous cell carcinoma in Australia. Journal of Oncology, 2014 (Article No. 236482) 236482, 236482-7. doi: 10.1155/2014/236482
Thomson I.G., Gotley D.C., Barbour A.P., Martin I., Jayasuria N., Thomas J. and Smithers B.M. (2014). Treatment results of curative gastric resection from a specialist Australian unit: Low volume with satisfactory outcomes. Gastric Cancer, 17 (1), 152-160. doi: 10.1007/s10120-013-0240-3
Hughes, Maria Celia, Wright, Annaliesa, Barbour, Andrew, Thomas, Janine, Smithers, B. Mark, Green, Adele C. and Khosrotehrani, Kiarash (2013). Patients undergoing lymphadenectomy for Stage III melanomas of known or unknown primary site do not differ in outcome. International Journal of Cancer, 133 (12), 3000-3007. doi: 10.1002/ijc.28318
Early diagnostic biomarkers for esophageal adenocarcinoma: the current state of play
Shah, Alok Kishorkumar, Saunders, Nicholas A., Barbour, Andrew P. and Hill, Michelle M. (2013). Early diagnostic biomarkers for esophageal adenocarcinoma: the current state of play. Cancer Epidemiology: Biomarkers and Prevention, 22 (7), 1185-1209. doi: 10.1158/1055-9965.EPI-12-1415
Role of human papillomaviruses in esophageal squamous cell carcinoma
Liyanage, Surabhi S., Segelov, Eva, Garland, Suzanne M., Tabrizi, Sepehr N., Seale, Holly, Crowe, Philip J., Dwyer, Dominic E., Barbour, Andrew, Newall, Anthony T., Malik, Aisha and Macintyre, C. Raina (2013). Role of human papillomaviruses in esophageal squamous cell carcinoma. Asia-Pacific Journal of Clinical Oncology, 9 (1), 12-28. doi: 10.1111/j.1743-7563.2012.01555.x
Impact of postoperative morbidity on long-term survival after oesophagectomy
Hii, M. W., Smithers, B. M., Gotley, D. C., Thomas, J. M., Thomson, I., Martin, I. and Barbour, A. P. (2013). Impact of postoperative morbidity on long-term survival after oesophagectomy. British Journal of Surgery, 100 (1), 95-104. doi: 10.1002/bjs.8973
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Gingras, Marie-Claude, Muthuswamy, Lakshmi B., Johns, Amber L., Miller, David K., Wilson, Peter J., Patch, Ann-Marie, Wu, Jianmin, Chang, David K., Cowley, Mark J., Gardiner, Brooke B., Song, Sarah, Harliwong, Ivon, Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Pajic, Marina, Scarlett, Christopher J., Gill, Anthony J., Pinho, Andreia V., Rooman, Ilse, Anderson, Matthew, Holmes, Oliver, Leonard, Conrad ... Grimmond, Sean M. (2012). Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature, 491 (7424), 399-405. doi: 10.1038/nature11547
Surgical management in patients with pancreatic cancer: a Queensland perspective
Wylie, Neil, Adib, Reza, Barbour, Andrew P., Fawcett, Jonathan, Hill, Alexander, Lynch, Stephen, Martin, Ian, O'Rourke, Thomas R., Puhalla, Harald, Rutherford, Leigh, Slater, Kellee, Whiteman, David C., Neale, Rachel E. and Queensland Pancreatic Cancer Study Group (2012). Surgical management in patients with pancreatic cancer: a Queensland perspective. ANZ Journal of Surgery, 83 (11), 859-864. doi: 10.1111/j.1445-2197.2012.06312.x
Clinical issues in oesophageal adenocarcinoma: could DNA copy number hold the key?
Frankel, Adam, Nancarrow, Derek, Wayte, Nicola and Barbour, Andrew (2012). Clinical issues in oesophageal adenocarcinoma: could DNA copy number hold the key?. Anz Journal of Surgery, 82 (9), 599-606. doi: 10.1111/j.1445-2197.2012.06144.x
Gordon, Louisa G., Hirst, Nicholas G., Mayne, George C., Watson, David I., Bright, Timothy, Cai, Wang, Barbour, Andrew P., Smithers, Bernard M., Whiteman, David C. and Eckermann, Simon (2012). Modeling the cost-effectiveness of strategies for treating esophageal adenocarcinoma and high-grade dysplasia. Journal of Gastrointestinal Surgery, 16 (8), 1451-1461. doi: 10.1007/s11605-012-1911-9
Foote, Matthew, Burmeister, Bryan, Dwyer, Patrick, Burmeister, Elizabeth, Lambie, Duncan, Allan, Christopher, Barbour, Andrew, Bayley, Gerard, Pullar, Andrew, Meakin, Janelle, Thomas, Janine and Smithers, Mark (2012). An innovative approach for locally advanced stage III cutaneous melanoma: radiotherapy, followed by nodal dissection. Melanoma Research, 22 (3), 257-262. doi: 10.1097/CMR.0b013e3283531335
Andersen, Jesper B., Spee, Bart, Blechacz, Boris R., Avital, Itzhak, Komuta, Mina, Barbour, Andrew, Conner, Elizabeth A., Gillen, Matthew C., Roskams, Tania, Roberts, Lewis R., Factor, Valentina M. and Thorgeirsson, Snorri S. (2012). Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors. Gastroenterology, 142 (4), 1021-1031.e15. doi: 10.1053/j.gastro.2011.12.005
Management of loco-regionally recurrent melanoma
Geere, Simone L. and Barbour, Andrew P. (2012). Management of loco-regionally recurrent melanoma. Cancer Forum, 36 (3), 166-170.
Sjoquist, Katrin M., Burmeister, Bryan H., Smithers, B. Mark, Zalcberg, John R., Simes, R. John, Barbour, Andrew, Gebski, Val and for the Australasian Gastro-Intestinal Trials Group (2011). Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis. Lancet Oncology, 12 (7), 681-692. doi: 10.1016/S1470-2045(11)70142-5
Defining cure for esophageal cancer: Analysis of actual 5-year survivors following esophagectomy
Hirst, Jodi, Smithers, Bernard Mark, Gotley, David C., Thomas, Janine and Barbour, Andrew (2011). Defining cure for esophageal cancer: Analysis of actual 5-year survivors following esophagectomy. Annals of Surgical Oncology, 18 (6), 1766-1774. doi: 10.1245/s10434-010-1508-z
Burmeister, Bryan H., Thomas, Janine M., Burmeister, Elizabeth A., Walpole, Euan T., Harvey, Jennifer A., Thomson, Damien B., Barbour, Andrew P., Gotley, David C. and Smithers, B. Mark (2011). Is concurrent radiation therapy required in patients receiving preoperative chemotherapy for adenocarcinoma of the oesophagus? A randomised phase II trial. European Journal of Cancer, 47 (3), 354-360. doi: 10.1016/j.ejca.2010.09.009
Biomarkers in oesophagogastric cancers
Cameron, Andrew, Barbour, Andrew, Wayte, Nicci and Akhurst, Tim (2011). Biomarkers in oesophagogastric cancers. Cancer Forum, 35 (3), 160-166.
Risk stratification for early esophageal adenocarcinoma: Analysis of lymphatic spread
Barbour, Andrew P., Jones, Mark, Brown, Ian, Gotley, David C., Martin, Ian, Thomas, Janine, Clouston, Andre and Smithers, B. Mark (2010). Risk stratification for early esophageal adenocarcinoma: Analysis of lymphatic spread. Annals of Surgical Oncology, 17 (9), 2494-2502. doi: 10.1245/s10434-010-1025-0
Thomson, Iain G., Smithers, Bernard M., Gotley, David C., Martin, Ian, Thomas, Janine M., O'Rourke, Peter and Barbour, Andrew P. (2010). Thoracoscopic-assisted esophagectomy for esophageal cancer: Analysis of patterns and prognostic factors for recurrence. Annals of Surgery, 252 (2), 281-291. doi: 10.1097/SLA.0b013e3181e909a2
Isolated limb infusion for malignant melanoma: Predictors of response and outcome
Barbour, A. P., Thomas, J., Suffolk, J., Beller, E. and Smithers, B. M, (2009). Isolated limb infusion for malignant melanoma: Predictors of response and outcome. Annals of Surgical Oncology, 16 (12), 3463-3472. doi: 10.1245/s10434-009-0717-9
Shenfine, J., Barbour, A. P., Wong, D., Martin, I., Gotley, D. C. and Smithers, B. M. (2009). Prognostic value maximum standardized uptake value from preoperative positron emission tomography in resectable adenocarcinoma of the esophagus treated by surgery alone. Diseases of the Esophagus, 22 (8), 668-675. doi: 10.1111/j.1442-2050.2009.00941.x
Refining esophageal cancer staging after neoadjuvant therapy: importance of treatment response
Barbour, A.P., Jones, M., Gonen, M., Gotley, D.C., Thomas, J., Thomson, D.B., Burmeister, B. and Smithers, B.M. (2008). Refining esophageal cancer staging after neoadjuvant therapy: importance of treatment response. Annals of Surgical Oncology, 15 (10), 2894-2902. doi: 10.1245/s10434-008-0084-y
Consideration of mesh-related complications: Letters and comments
Shenfine, Jon, Barbour, Andrew, Martin, Ian, Smithers, B. Mark and Gotley, David C. (2008). Consideration of mesh-related complications: Letters and comments. Annals of the Royal College of Surgeons of England, 90 (2), 175-176. doi: 10.1308/003588408X261780
Barbour, A.P., Lagergren, P., Hughes, R., Alderson, D., Barham, C.P. and Blazeby, J.M. (2008). Health-related quality of life among patients with adenocarcinoma of the gastro-oesophageal junction treated by gastrectomy or oesophagectomy. British Journal of Surgery, 95 (1), 80-84. doi: 10.1002/bjs.5912
Barbour, Andrew P., Rizk, Nabil P., Gerdes, Hans, Bains, Manjit S., Rusch, Valerie W., Brennan, Murray F. and Coit, Daniel G. (2007). Endoscopic ultrasound predicts outcomes for patients with adenocarcinoma of the gastroesophageal junction. Journal of the American College of Surgeons, 205 (4), 593-601. doi: 10.1016/j.jamcollsurg.2007.05.010
Barbour, Andrew P., Rizk, Nabil P., Gonen, Mithat, Tang, Laura, Bains, Manjit S., Rusch, Valerie W., Coit, Daniel G. and Brennan, Murray F. (2007). Adenocarcinoma of the gastroesophageal junction: Influence of esophageal resection margin and operative approach on outcome. Annals of Surgery, 246 (1), 1-8. doi: 10.1097/01.sla.0000255563.65157.d2
Barbour, Andrew P., Rizk, Nabil P., Gonen, Mithat, Tang, Laura, Bains, Manjit S., Rusch, Valerie W., Coit, Daniel G. and Brennan, Murray F. (2007). Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): Impact of adequate staging on outcome. Annals of Surgical Oncology, 14 (2), 306-316. doi: 10.1245/s10434-006-9166-x
Smithers, B. M., Cullinan, M., Thomas, J. M., Martin, I., Barbour, A. P., Burmeister, B. H., Harvey, J. A., Thomson, D. B., Walpole, E. T. and Gotley, D. C. (2007). Outcomes from salvage esophagectomy post definitive chemoradiotherapy compared with resection following preoperative neoadjuvant chemoradiotherapy. Diseases of The Esophagus, 20 (6), 471-477. doi: 10.1111/j.1442-2050.2007.00701.x
Current concepts of tumour metastasis
Barbour, A. and Gotley, D. C. (2003). Current concepts of tumour metastasis. Annals Academy of Medicine Singapore, 32 (2), 176-184.
Barbour, A. P., Reeder, J. A., Walsh, M. D., Fawcett, J., Antalis, T. M. and Gotley, D. C. (2003). Expression of the CD44v2-10 isoform confers a metastatic phenotype: Importance of the heparan sulfate attachment site CD44v3. Cancer Research, 63 (4), 887-892.
Barbour, A. P., Brosda, S., Wijnhoven, B., van Hootgem, S., Lanschot, J. J. B., Barbour, S., Lagarde, S., Krause, L., Pryor, D., Thomas, J., Walpole, E. T., van der Gaast, A. and Smithers, M. (2018). Neoadjuvant therapy for esophageal adenocarcinoma: a propensity score-matched comparison of paclitaxel and carboplatin chemoradiotherapy with cisplatin and 5-fluoruracil-based chemo- or chemoradiotherapy. 43rd ESMO Congress (ESMO), Munich, Germany, 19-23 October 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/annonc/mdy282.015
Barbour, Andrew P., McCormack, Orla M. , Baker, Peter J., Hirst, Jodi, Krause, Lutz, Brosda, Sandra, Thomas, Janine M., Blazeby, Jane M., Thomson, Iain G., Gotley, David C. and Smithers, Bernard M. (2017). Long-term health-related quality of life following esophagectomy: A nonrandomized comparison of thoracoscopically assisted and open surgery. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/SLA.0000000000001899
Barbour, A., Walpole, E., Mai, G. T., Chan, H., Barnes, E., Watson, D., Ackland, S., Wills, V., Martin, J., Burge, M., Karapetis, C., Shannon, J., Nott, L., Gebski, V., Wilson, K., Thomas, J., Lampe, G., Zalcberg, J., Simes, J. and Smithers, M. (2016). An AGITG trial - A randomised phase II study of pre-operative cisplatin, fluorouracil and DOCetaxel plus /-radio Therapy based on poOR early response to cisplatin and fluorouracil for resectable esophageal adenocarcinoma. 41st Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, Denmark, 7-11 October 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/annonc/mdw371.02
Rowe, C., Tang, F., Hughes, M. C., Rodero, M., Malt, M., Lambie, D., Barbour, A., Hayward, N., Smithers, B. M., Green, A. and Khosrotehrani, K. (2016). Prognostic value of nomograms incorporating biomarkers vs. sentinel node status in patients with stage IB and II melanoma. Australasian College of Dermatologists 49th Annual Scientific Meeting, Perth, Australia, 14–17 May, 2016. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12480
Shah, Alok K., Chen, David, Le Cao, Kim-Anh, Choi, Eunju, Nancarrow, Derek, Whiteman, David, Saunders, Nicholas A., Barbour, Andrew P. and Hill, Michelle M. (2014). Discovery and validation of novel serum glycoprotein biomarkers for Barrett's esophagus and esophageal adenocarcinoma. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-2492
Oesophageal adenocarcinoma genomics
Barbour, Andrew (2014). Oesophageal adenocarcinoma genomics. Sydney Cancer Conference, The University of Sydney, Australia, 26 November 2014. West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12282
Barbour, Andrew, Smithers, Bernard Mark, Burmeister, Bryan, Zalcberg, John Raymond, Spry, Nigel, Smith, Garrett, Wilson, Kate, Roff, Kate, Yip, Sonia and Walpole, Euan Thomas (2012). DOCTOR: A randomized phase II trial of preoperative cisplatin, 5-fluorouracil, and docetaxel with or without radiotherapy based on poor early response to standard chemotherapy for resectable adenocarcinoma of the esophagus and/or OG junction. 48th Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, Il United States, 01-06 June 2012. Alexandria, VA United States: American Society of Clinical Oncology.
Gene expression analysis of EAC in association with PET response.
Wayte, Nicola, Nancarrow, Derek, Walpole, Euan Thomas, Lampe, Guy, Gotley, David, Smithers, Bernard Mark and Barbour, Andrew (2012). Gene expression analysis of EAC in association with PET response.. ASCO GI Symposium, San Diego, California, 24 January 2012. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/jco.2012.30.4_suppl.50
Andersen, Jesper B., Spee, Bart, Blechacz, Boris, Avital, Itzhak, Komuta, Mina, Barbour, Andrew, Roskams, Tania, Roberts, Lewis R., Factor, Valentina M. and Thorgeirsson, Snorri S. (2011). Genomic and genetic characterization of human Cholangiocarcinoma identifies treatment options for tyrosine kinase inhibitors. 62nd Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA, United States, 04-08 November 2011.
Burmeister, B. H., Smithers, B. M., Thomas, J., Burmeister, E., Walpole, E., Harvey, J., Thomson, D., Barbour, A. and Gotley D. (2008). A randomised phase II trial comparing pre-operative chemotherapy with pre-operative chemoradiation therapy for localized carcinoma of the oesophagus. Clinical Oncological Society of Australia and the International Association of Cancer Registries Joint Scientific Meeting, held in conjunction with the Australian and New Zealand Gastro-Oesophageal Surgery Association, Sydney, Australia, 18-20 November 2008. United Kingdom: Wiley-Blackwell. doi: 10.1111/j.1743-7563.2008.00201_1.x
Barbour, A., Thompson, I., Gotley, D. C., Jones, M., Thomas, J., Martin, I. and Smithers, M. B. (2008). Minimally invasive esophagectomy for esophageal cancer: Analysis of recurrence patterns and prognostic factors of recurrence. Clinical Oncological Society of Australia and the International Association of Cancer Registries Joint Scientific Meeting, held in conjunction with the Australian and New Zealand Gastro-Oesophageal Surgery Association, Sydney, Australia, 18–20 November 2008. United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/j.1743-7563.2008.00201_2.x
Surgery for early esophageal adenocarcinoma: Analysis of lymphatic spread and prognostic factors
Hughes, A., Smithers, B. M., Thomas, J., Martin, I., Gotley, D. C. and Barbour, A. P. (2007). Surgery for early esophageal adenocarcinoma: Analysis of lymphatic spread and prognostic factors. 60th Annual Cancer Symposium of the Society of Surgical Oncology, Washington, DC, USA, 15-18 Mar, 2007. Hagerstown, U.S.A.: Springer.
Isolated limb infusion (ILI) for malignant melanoma: Predictors of response and outcome
Barbour, A.P., Beller, E. and Smithers, B.M. (2006). Isolated limb infusion (ILI) for malignant melanoma: Predictors of response and outcome. The 59th Annual Cancer Symposium of the Society of Surgical Oncology, San Diego, CA, 23-26 March 2006. Hagerstown, U.S.A.: Springer.
Isolated limb infusion (ILT) for malignant melanoma: Predictors of response and outcome
Barbour, AP, Beller, E and Smithers, BM (2006). Isolated limb infusion (ILT) for malignant melanoma: Predictors of response and outcome. 59th Annual Cancer Symposium of the Society-of-Surgical-Oncology, San Diego CA, MAR 23-26, 2006. NEW YORK: SPRINGER.
Barbour, A. P., Smithers, B. M., Gotley, D. C., Thomas, J., Burmeister, B. H. and Walpole, E. T. (2006). Patterns and predictors of initial recurrence following resection for adenocarcinoma of the oesophagus and gastro-oesophageal junction. The RACS Annual Scientific Congress, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, 15-19 May 2006. Australia: Blackwell Publishing Asia.
Refining oesophageal cancer staging after neoadjuvant therapy: importance of primary tumour response
Barbour, A. P., Smithers, B. M., Gotley, D. C., Thomas, J., Burmeister, B. H. and Thompson, D. (2006). Refining oesophageal cancer staging after neoadjuvant therapy: importance of primary tumour response. The RACS Annual Scientific Congress, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, 15-19 May, 2006. Australia: Blackwell Publishing Asia.
Barbour, A., Reeder, J., Fawcett, J., Walsh, M., Antalis, T. M. and Gotley, D. C. (2000). Glycosaminoglycan-modified CD44v3 confers a metastatic phenotype on a human hepatocellular carcinoma (HCC) cell line in a murine model. 91st Annual Meeting of American Association for Cancer Research, San Francisco, 1-5 Apr, 2000. Philadelphia, U.S.A.: American Association for Cancer Research.
(2023–2026) CCQ Accelerating Collaborative Cancer Research
(2021–2024) Cancer Council Queensland
Improving outcomes for patients with melanoma brain metastases
(2020–2025) Community Skilling & Disability Support Service Inc (trading name: Civic Solutions)
(2020–2021) PA Research Foundation
(2019–2024) University of Sydney
(2019–2023) NHMRC Development Grant
Blood biomarkers to predict recurrence in BRAF- negative melanoma patients
(2019–2022) Queensland Advancing Clinical Research Fellowship
Targeting the pre-metastatic vascular niche in melanoma using a novel molecular strategy
(2019–2022) NHMRC Project Grant
(2019–2021) Metro South Hospital and Health Service
(2018–2023) Research Donation Generic
(2018–2022) Metro South Hospital and Health Service
(2018–2021) Queensland Institute of Medical Research
A novel theranostic for pancreatic cancer
(2017–2019) Avner Pancreatic Cancer Foundation Limited
(2017) Royal Australasian College of Surgeons
DOCTOR trial genomic sub-study
(2016–2017) Australasian Gastro-Intestinal Trials Group
Obesity-induced Barrett's oesophagus and associated cancer: mechanisms and diagnostic tools
(2016–2017) TRI Spore Grants
Donation for cancer research from Ms D. Jameson and the Estate of the late Alec Pearman
(2015–2023) Research Donation Generic
DOCTOR Trial Genomics Substudy
(2015–2016) Cancer Bequest Fund
(2015–2016) University of Sydney
Understanding Oesophageal Cancer Response to Therapy: The DOCTOR Trial Genomics Substudy
(2015) Princess Alexandra Hospital R&D Foundation
Complement C3a receptor, a novel therapeutic target for melanoma
(2014–2015) Cancer Council Queensland
New blood tests for Barrett's oesophagus and oesophageal cancer
(2014–2015) UQ-Ochsner Seed Fund for Collaborative Research - MABS funds
High throughput gene expression of patient samples via the Nanostring nCounter system
(2014) UQ Major Equipment and Infrastructure
(2013) PA Research Foundation
(2012–2014) NHMRC Project Grant
Biomarkers for Stage III Melanoma Recurrence and Response to Radiotherapy
(2012–2013) PA Research Foundation
(2011) NHMRC Project Grant
Cancer Collaborative Group Translational Project Grant
(2010–2012) PA Research Foundation
Genome-wide analysis of Oesophageal cancer: towards biomarkers of response and outcome
(2010–2011) Cancer Council Queensland
Exploration of the existence and significance of CSCs in Gastric Cancer
(2008) Cancer Bequest Fund
CD44v3 and v6 As Targets For Anti-Metastasis Therapy
(2003–2006) NHMRC Project Grant
Mechanisms Of CD44v2-10-Mediated Tumour Metastasis
(2003–2006) NHMRC Project Grant
CD44 Splice Variants in Colorectal Tumour Progression and Metastasis
(2000) Princess Alexandra Hospital R&D Foundation
The role of CD44 splice variants in colorectal tumour progression and metastasis
(2000)
Studies of the Mechanism of CD44 Mediation of Colorectal Tumour Proliferation and Metastasis
(1998) Princess Alexandra Hospital R&D Foundation
Harnessing tumour immune responses in oesophageal cancer: towards better personalised therapeutic strategies
Doctor Philosophy — Principal Advisor
Other advisors:
Deep spatial phenotyping analysis to characterize cancer evolution
Doctor Philosophy — Associate Advisor
Other advisors:
Immune regulation through bi-directional interactions between subsets of Natural Killer cells and Dendritic cells.
Doctor Philosophy — Associate Advisor
(2020) Doctor Philosophy — Principal Advisor
Genomic investigations in oesophageal adenocarcinoma: towards biomarkers of prognosis
(2013) Doctor Philosophy — Principal Advisor
Human dendritic cell immunoprofiling in advanced melanoma patients and responses to immunotherapy
(2019) Doctor Philosophy — Associate Advisor
Other advisors:
Lipid Metabolism in Barrett's Esophagus and Esophageal Adenocarcinoma
(2019) Doctor Philosophy — Associate Advisor
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
Serum diagnostic glycoprotein biomarkers for Barrett's esophagus and esophageal adenocarcinoma
(2015) Doctor Philosophy — Associate Advisor