Professor Matt Trau is currently a Professor of Chemistry at The University of Queensland (UQ); and is also Senior Group Leader and co-founder of the Australian Institute for Bioengineering and Nanotechnology. Since graduating from the University of Sydney (BSc Hons I, University Medal) and the University of Melbourne (PhD in Physical Chemistry, 1993), he has held positions in industry and academia across the globe. These include a Fulbright Research Fellowship at Princeton University, USA; and a research scientist at Dow Chemical and ICI Pty Ltd. Professor Trau has been a Visiting Professor at two of the largest Cancer Research Centres in the world: The Dana Farber Cancer Research Institute, Harvard Medical School, Boston (2000); and the Fred Hutchinson Cancer Research Centre, Seattle (2008). Professor Trau is internationally recognised for his innovative and cross-disciplinary research at the interface between chemistry, nanotechnology, biology and medicine. He has co-authored more than 200 refereed publications, many of which appear in the highest impact journals in his field, e.g., eleven Science and Nature family publications. His major awards and honours include an ARC Federation Fellowship (one of the most prestigious scientific fellowships in Australia), a Fulbright Research Fellowship to the USA; a Queensland Young Tall Poppy Award; a UQ Foundation/Vice Chancellor’s Research Excellence Award; a Paul Harris Fellowship; and a Pink Circle Award for breast cancer research excellence.
Research
Nanoscience, Nanotechnology, Molecular diagnostics.
Leadership of major multi-disciplinary international programs
Professor Trau has raised more than $22 million in competitive national and international grant funding in the past 10 years. In the last five years, Professor Trau has initiated and led several large international programs that involve close collaboration between leading nanotechnologists, molecular biologists, geneticists and commercial researchers - with the goal of creating cutting edge diagnostics. These include a $4 million National and International Research Alliances Program (NIRAP) grant from the Queensland government ("International Partnership for preventative and Personalised Medicine)"; and two consecutive $5 million multidisciplinary collaborative grants from the National Breast Cancer Foundation (NBCF): "Novel strategies for Prediction and Control of Advanced Breast Cancer via Nanoscaled Epigenetic-Based Biosensors", 2008-2013; and "Enabling Clinical Epigenetic Diagnostics: The Next Generation of Personalized Breast Cancer Care", 2013-2018. These grants involve research collaborations with some of the highest calibre scientists in the world, e.g., Dr Lee Hartwell (2001 Nobel Laureate) from Seattle was a co-chief investigator on the NIRAP grant, and each of the NBCF grants include leading geneticists, pathologists and oncologists from across Australia and around the world. In the past five years, he has been a consultant for a range of national and international companies such as Merck, Digene, Beckman Coulter, Panbio and A.I. Scientific, as well as being the founder and Director of Nanomics BioSystems Pty Ltd (a spinoff company from his laboratory).
Major plenary lectures and international conferences
Since 2003, Professor Trau has presented more than 60 invited plenary/keynote lectures at major international conferences spanning the disciplines of Chemistry, Nanotechnology, Chemical Engineering, Cancer and Diagnostics. Recent examples include: the 4th International NanoBio Conference, (Seattle) 2012; the 14th International Colloid & Surface Science Conference, (Japan) 2012; "Cancer Nanotechnology" Gordon Research Conference, (USA) 2011; the WA Cancer Conference 2011; Sydney Cancer Conference, 2010. In the past 10 years, Professor Trau has played the role of conference convenor, chair, co-chair and symposium chair for 10 major international conferences. Recent examples include: immediate past chair of the 1st International Conference on BioNano Innovation, (Brisbane) 2012; co-chair of the 5th International NanoBio Conference scheduled for Brisbane in 2014.
Journal Article: Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae
Lu, Zeyu, Shen, Qianyi, Liu, Lian, Talbo, Gert, Speight, Robert, Trau, Matt, Dumsday, Geoff, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2023). Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae. Engineering Microbiology, 3 (3) 100079, 100079. doi: 10.1016/j.engmic.2023.100079
Journal Article: A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell
Ahmed, Emtiaz, Shanmugasundaram, Karthik Balaji, Li, Junrong, Behren, Andreas, Lobb, Richard, Möller, Andreas, Wuethrich, Alain, Dey, Shuvashis, Sina, Abu Ali Ibn and Trau, Matt (2023). A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell. Advanced Sensor Research. doi: 10.1002/adsr.202300059
Journal Article: A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments
Li, Junrong, Howard, Christopher B., Dey, Shuvashis, Lowry, Kym, Whiley, David M., Puttick, Simon, Rose, Stephen, Lobb, Richard J., Wuethrich, Alain, Edwardraja, Selvakumar and Trau, Matt (2023). A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments. Nature Nanotechnology. doi: 10.1038/s41565-023-01415-1
Digital chemistry and catalysis: redefining reactions in confined systems
(2024–2028) ARC Australian Laureate Fellowships
(2023–2027) University of Sydney
An integrated nano-bioengineered chip for enhanced molecular evolution
(2022–2025) ARC Discovery Projects
Bioengineering yeast nanofragment affinity probes for dengue diagnostics
Doctor Philosophy
Novel Nanotechnology Platforms for Cancer Diagnostics
(2023) Doctor Philosophy
Single-nanoparticle upconversion nanolasers for probing biological systems
Doctor Philosophy
Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications
Muhammad J. A. Shiddiky, Eugene J. H. Wee, Sakandar Rauf and Matt Trau eds. (2013). Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications. New Developments in Medical Research, United States: Nova Science Publishers.
Wang, Jing, Trau, Matt and Wuethrich, Alain (2023). A Microfluidic SERS Assay to Characterize the Phenotypic Heterogeneity in Cancer-Derived Small Extracellular Vesicles. Microfluidic Systems for Cancer Diagnosis. (pp. 241-253) New York, NY: Springer US. doi: 10.1007/978-1-0716-3271-0_17
Multiplex PCR Design for Scalable Resequencing
Korbie, Darren and Trau, Matt (2022). Multiplex PCR Design for Scalable Resequencing. Methods in Molecular Biology. (pp. 143-158) New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-1799-1_11
Wuethrich, Alain, Dey, Shuvashis, Koo, Kevin M, Sina, Abu A. I. and Trau, Matt (2021). Simultaneous BRAFV600E protein and DNA aberration detection in circulating melanoma cells using an integrated multimolecular sensor. Melanoma. (pp. 265-276) New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1205-7_20
Ng, Benjamin Y.C., Wee, Eugene J.H., West, Nicholas P. and Trau, Matt (2019). Nucleic Acid Detection of Tuberculosis Via Innovative Point-of-Care Nanotechnologies Targeted for Low Resource Settings. Revolutionizing Tropical Medicine. (pp. 584-599) Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/9781119282686.ch33
Interfacial biosensing: direct biosensing of biomolecules at the bare metal interface
Ibn Sina, A. A., Koo, K. M., Ahmed, M., Carrascosa, L. G. and Trau, M. (2018). Interfacial biosensing: direct biosensing of biomolecules at the bare metal interface. Encyclopedia of interfacial chemistry: surface science and electrochemistry. (pp. 269-277) Amsterdam: Elsevier. doi: 10.1016/b978-0-12-409547-2.14188-5
Purification protocols for extracellular vesicles
Lane, Rebecca E., Korbie, Darren, Trau, Matt and Hill, Michelle M. (2017). Purification protocols for extracellular vesicles. In Winston Patrick Kuo and Shidong Jia (Ed.), Extracellular vesicles: methods and protocols (pp. 111-130) New York, United States: Humana Press. doi:10.1007/978-1-4939-7253-1_10
Detecting DNA methylation for cancer diagnostics and prognostics
Wee, Eugene J. H., Shiddiky, Muhammad J. A. and Trau, Matt (2013). Detecting DNA methylation for cancer diagnostics and prognostics. Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications. (pp. 117-132) edited by Muhammad J. A. Shiddiky, Eugene J. H. Wee, Sakandar Rauf and Matt Trau. New York, NY, United States: Nova Publishers.
Shiddiky, Muhammad J.A., Wee, Eugene J.H., Rauf, Sakandar and Trau, Matt (2013). Preface. Microfluidics, nanotechnology and disease biomarkers for personalized medicine applications. edited by Muhammad J. A. Shiddiky, Eugene J. H. Wee, Sakandar Rauf and Matt Trau. Hauppauge, NY, United States: Nova Science Publishers.
Biosensors for disease biomarker detection
Battersby, B. J., Chen, A., Kozak, D. and Trau, M. (2012). Biosensors for disease biomarker detection. Biosensors for medical applications. (pp. 191-216) edited by Seamus Higson. Oxford, United Kingdom: Woodhead Publishing. doi: 10.1016/B978-1-84569-935-2.50007-3
Nanotechnology : the future of cost-effective plant genotyping
Pattemore, J. A., Trau, M. and Henry, R. J. (2008). Nanotechnology : the future of cost-effective plant genotyping. Plant genotyping II : SNP technology. (pp. 133-153) edited by R. J. Henry. Wallingford, United Kingdom: CABI Publishing. doi: 10.1079/9781845933821.0133
Colloids for encoding chemical libraries: Applications in biological screening
Battersby, Bronwyn J., Grondahl, Lisbeth, Lawrie, Gwendolyn A. and Trau, Matt (2004). Colloids for encoding chemical libraries: Applications in biological screening. Colloids and Colloid Assemblies. (pp. 507-560) edited by F. Caruso. Weinheim: Wiley VCH. doi: 10.1002/3527602100.ch17
Lu, Zeyu, Shen, Qianyi, Liu, Lian, Talbo, Gert, Speight, Robert, Trau, Matt, Dumsday, Geoff, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2023). Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae. Engineering Microbiology, 3 (3) 100079, 100079. doi: 10.1016/j.engmic.2023.100079
Ahmed, Emtiaz, Shanmugasundaram, Karthik Balaji, Li, Junrong, Behren, Andreas, Lobb, Richard, Möller, Andreas, Wuethrich, Alain, Dey, Shuvashis, Sina, Abu Ali Ibn and Trau, Matt (2023). A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell. Advanced Sensor Research. doi: 10.1002/adsr.202300059
Li, Junrong, Howard, Christopher B., Dey, Shuvashis, Lowry, Kym, Whiley, David M., Puttick, Simon, Rose, Stephen, Lobb, Richard J., Wuethrich, Alain, Edwardraja, Selvakumar and Trau, Matt (2023). A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments. Nature Nanotechnology. doi: 10.1038/s41565-023-01415-1
Ahmed, Mostak, Wuethrich, Alain, Constantin, Nicolas, Shanmugasundaram, Karthik Balaji, Mainwaring, Paul, Kulasinghe, Arutha, O’Leary, Connor, O’Byrne, Ken, Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2023). Liquid Biopsy Snapshots of Key Phosphoproteomic Pathways in Lung Cancer Patients for Diagnosis and Therapy Monitoring. Analytical Chemistry, 95 (22), 8522-8532. doi: 10.1021/acs.analchem.3c00519
Graeser, M., Harbeck, N., Gluz, O., Nitz, U.A., Christgen, M., Kuemmel, S., Grischke, E-M., Forstbauer, H., Braun, M., Warm, M., Hackmann, J.C., Uleer, C., Aktas, B., Würstlein, R., Pelz, E., Eulenburg, C. Zu, Kreipe, H., Trau, M., Stirzaker, C. and Korbie, D. (2023). 18P A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC). ESMO Open, 8 (1) 101242, 101242. doi: 10.1016/j.esmoop.2023.101242
A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern
Vedelago, Courtney, Li, Junrong, Lowry, Kym, Howard, Christopher, Wuethrich, Alain and Trau, Matt (2023). A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern. ACS Sensors, 8 (4), 1648-1657. doi: 10.1021/acssensors.2c02782
Li, Junrong, Sina, Abu A. I., Antaw, Fiach, Fielding, David, Möller, Andreas, Lobb, Richard, Wuethrich, Alain and Trau, Matt (2023). Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions. Advanced Science, 10 (1) 2204207. doi: 10.1002/advs.202204207
Dey, Shuvashis, Koo, Kevin M., Ahmed, Emtiaz and Trau, Matt (2023). Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy. Lab on a Chip, 23 (15), 3443-3452. doi: 10.1039/d3lc00523b
Yuan, Liwen, Chen, Yanping, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and wang, jing (2023). Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease. Nanoscale Horizons, 8 (6), 746-758. doi: 10.1039/d2nh00570k
Wang, Jing, Koo, Kevin M. and Trau, Matt (2022). Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy. Analytical Chemistry, 94 (43), 14906-14916. doi: 10.1021/acs.analchem.2c02262
Li, Junrong, Wuethrich, Alain, Zhang, Zhen, Wang, Jing, Lin, Lynlee L., Behren, Andreas, Wang, Yuling and Trau, Matt (2022). SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy. Analytical Chemistry, 94 (42), 14573-14582. doi: 10.1021/acs.analchem.2c02398
Farokhinejad, Fahimeh, Li, Junrong, Hugo, Leon E., Howard, Christopher B., Wuethrich, Alain and Trau, Matt (2022). Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes. Analytical Chemistry, 94 (41), 14177-14184. doi: 10.1021/acs.analchem.2c02012
Johnston, Andrew D., Lu, Jennifer, Korbie, Darren and Trau, Matt (2022). Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis. Scientific Reports, 12 (1) 16051, 1-18. doi: 10.1038/s41598-022-18196-7
An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae
Peng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications, 13 (1) 2895, 2895. doi: 10.1038/s41467-022-30529-8
A T‐junction dual nanopore for single nanoparticle analysis
Liao, Caizhi, Antaw, Fiach, Wuethrich, Alain and Trau, Matt (2022). A T‐junction dual nanopore for single nanoparticle analysis. Advanced Engineering Materials, 24 (4) 2101015, 2101015. doi: 10.1002/adem.202101015
Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul and Hill, Michelle M. (2022). C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma. Frontiers in Immunology, 13 842023, 842023. doi: 10.3389/fimmu.2022.842023
Kenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363
Dey, Shuvashis, Ahmed, Emtiaz, Somvanshi, Pranjal Satishchandra, Sina, Abu Ali Ibn, Wuethrich, Alain and Trau, Matt (2022). An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers. Chemosensors, 10 (3) 93. doi: 10.3390/chemosensors10030093
Peng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z
Constantin, Nicolas, Sina, Abu Ali Ibn, Korbie, Darren and Trau, Matt (2022). Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies. Epigenomes, 6 (1) 6. doi: 10.3390/epigenomes6010006
Shanmugasundaram, Karthik Balaji, Li, Junrong, Sina, Abu Ibn, Wuethrich, Alain and Trau, Matt (2022). Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy. Materials Advances, 3 (3), 1459-1471. doi: 10.1039/d1ma00848j
Koo, Kevin M. and Trau, Matt (2022). Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing. Nanoscale, 14 (11), 4225-4233. doi: 10.1039/d1nr07845c
Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis
Zhang, Zhen, Wuethrich, Alain, Wang, Jing, Korbie, Darren, Lin, Lynlee L. and Trau, Matt (2021). Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis. Analytical Chemistry, 93 (50) acs.analchem.1c03167, 16787-16795. doi: 10.1021/acs.analchem.1c03167
Fitzpatrick, Kira J., Rohlf, Hayden J., Sutherland, Tara D., Koo, Kevin M., Beckett, Sam, Okelo, Walter O., Keyburn, Anthony L., Morgan, Branwen S., Drigo, Barbara, Trau, Matt, Donner, Erica, Djordjevic, Steven P. and De Barro, Paul J. (2021). Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains. ACS Sensors, 6 (12) acssensors.1c01973, 4283-4296. doi: 10.1021/acssensors.1c01973
Farokhinejad, Fahimeh, Lane, Rebecca E., Lobb, Richard J., Edwardraja, Selvakumar, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2021). Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection. ACS Biomaterials Science and Engineering, 7 (12) acsbiomaterials.1c01001, 5850-5860. doi: 10.1021/acsbiomaterials.1c01001
Wang, Jing, Kao, Yung‐Ching, Zhou, Quan, Wuethrich, Alain, Stark, Mitchell S., Schaider, Helmut, Soyer, H. Peter, Lin, Lynlee L. and Trau, Matt (2021). An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas. Advanced Functional Materials, 32 (3) 2010296, 1-9. doi: 10.1002/adfm.202010296
Li, Junrong, Wuethrich, Alain, Edwardraja, Selvakumar, Lobb, Richard J., Puttick, Simon, Rose, Stephen, Howard, Christopher B. and Trau, Matt (2021). Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassay. Analytical Chemistry, 93 (29) acs.analchem.1c01657, 10251-10260. doi: 10.1021/acs.analchem.1c01657
Wang, Jing, Wuethrich, Alain, Lobb, Richard J., Antaw, Fiach, Sina, Abu Ali Ibn, Lane, Rebecca E., Zhou, Quan, Zieschank, Chloe, Bell, Caroline, Bonazzi, Vanessa F., Aoude, Lauren G., Everitt, Sarah, Yeo, Belinda, Barbour, Andrew P., Möller, Andreas and Trau, Matt (2021). Characterizing the heterogeneity of small extracellular vesicle populations in multiple cancer types via an ultrasensitive chip. ACS Sensors, 6 (9) acssensors.1c00358, 3182-3194. doi: 10.1021/acssensors.1c00358
In situ single cell proteomics reveals circulating tumor cell heterogeneity during treatment
Reza, K. Kamil, Dey, Shuvashis, Wuethrich, Alain, Wang, Jing, Behren, Andreas, Antaw, Fiach, Wang, Yuling, Sina, Abu Ali Ibn and Trau, Matt (2021). In situ single cell proteomics reveals circulating tumor cell heterogeneity during treatment. ACS Nano, 15 (7) acsnano.0c10008, 11231-11243. doi: 10.1021/acsnano.0c10008
Webster, Julie A., Wuethrich, Alain, Shanmugasundaram, Karthik B., Richards, Renee S., Zelek, Wioleta M., Shah, Alok K., Gordon, Louisa G., Kendall, Bradley J., Hartel, Gunter, Morgan, B. Paul, Trau, Matt and Hill, Michelle M. (2021). Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma. Cancers, 13 (12) 2865, 2865. doi: 10.3390/cancers13122865
On the behavior of nanoparticles beyond the nanopore interface
Antaw, Fiach, Anderson, Will, Wuethrich, Alain and Trau, Matt (2021). On the behavior of nanoparticles beyond the nanopore interface. Langmuir, 37 (16), 4772-4782. doi: 10.1021/acs.langmuir.0c03083
Li, Junrong, Wuethrich, Alain, Sina, Abu A. I., Cheng, Han-Hao, Wang, Yuling, Behren, Andreas, Mainwaring, Paul N. and Trau, Matt (2021). A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy. Nature Communications, 12 (1) 1087, 1-12. doi: 10.1038/s41467-021-21431-w
Schwaber, Jessica L., Korbie, Darren, Andersen, Stacey, Lin, Erica, Chrysanthopoulos, Panagiotis K., Trau, Matt and Nielsen, Lars K. (2021). Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships. PLoS ONE, 16 (2 ) e0246107, e0246107. doi: 10.1371/journal.pone.0246107
Zeng, Yi, Koo, Kevin M., Shen, Ai-Guo, Hu, Ji-Ming and Trau, Matt (2021). Nucleic acid hybridization-based noise suppression for ultraselective multiplexed amplification of mutant variants. Small, 17 (2) 2006370, e2006370. doi: 10.1002/smll.202006370
Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level
Masud, Mostafa Kamal, Na, Jongbeom, Lin, Tzu-En, Malgras, Victor, Preet, Anant, Ibn Sina, Abu Ali, Wood, Kathleen, Billah, Mutasim, Kim, Jeonghun, You, Jungmok, Kani, Kenya, Whitten, Andrew E., Salomon, Carlos, Nguyen, Nam-Trung, Shiddiky, Muhammad J.A., Trau, Matt, Hossain, MdShahriar A. and Yamauchi, Yusuke (2020). Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level. Biosensors and Bioelectronics, 168 112429, 1-9. doi: 10.1016/j.bios.2020.112429
Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation
Lu, Jennifer, Wilfred, Premila, Korbie, Darren and Trau, Matt (2020). Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation. Cancers, 12 (11) 3199, 1-29. doi: 10.3390/cancers12113199
Stacked dual‐pore architecture for deciphering and manipulating dynamics of individual nanoparticles
Liao, Caizhi, Antaw, Fiach, Wuethrich, Alain and Trau, Matt (2020). Stacked dual‐pore architecture for deciphering and manipulating dynamics of individual nanoparticles. Advanced Materials Technologies, 5 (11) 2000701, 2000701. doi: 10.1002/admt.202000701
Koo, Kevin M. and Trau, Matt (2020). Direct enhanced detection of multiple circulating tumor dna variants in unprocessed plasma by magnetic-assisted bioelectrocatalytic cycling. ACS Sensors, 5 (10), 3217-3225. doi: 10.1021/acssensors.0c01512
Configurable miniaturized 3D pores for robust single‐nanoparticle analysis
Liao, Caizhi, Antaw, Fiach, Wuethrich, Alain, Anderson, Will and Trau, Matt (2020). Configurable miniaturized 3D pores for robust single‐nanoparticle analysis. Small Structures, 1 (2). doi: 10.1002/sstr.202000011
Li, Junrong, Wuethrich, Alain, Dey, Shuvashi, Lane, Rebecca E., Sina, Abu A. I., Wang, Jing, Wang, Yuling, Puttick, Simon, Koo, Kevin M. and Trau, Matt (2020). Multiomics: The Growing Impact of Micro/Nanomaterial‐Based Systems in Precision Oncology: Translating “Multiomics” Technologies (Adv. Funct. Mater. 37/2020). Advanced Functional Materials, 30 (37) 2070248. doi: 10.1002/adfm.202070248
Sina, Abu Ali Ibn, Ahmed, Emtiaz, Masud, Mostafa Kamal, Hossain, Md. Shahriar A., Na, Jongbeom, Yamauchi, Yusuke and Trau, Matt (2020). Nanostructured mesoporous gold electrodes detect protein phosphorylation in cancer with electrochemical signal amplification. Analyst, 145 (20), 6639-6648. doi: 10.1039/d0an01096k
Lam, Dilys, Luu, Phuc-Loi, Luu, Phuc-Loi, Song, Jenny Z., Qu, Wenjia, Risbridger, Gail P., Risbridger, Gail P., Risbridger, Gail P., Lawrence, Mitchell G., Lawrence, Mitchell G., Lawrence, Mitchell G., Lu, Jennifer, Trau, Matt, Korbie, Darren, Clark, Susan J., Clark, Susan J., Pidsley, Ruth, Pidsley, Ruth, Stirzaker, Clare and Stirzaker, Clare (2020). Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels. Clinical Epigenetics, 12 (1) 90, 90. doi: 10.1186/s13148-020-00880-y
Dey, Shuvashis, Trau, Matt and Koo, Kevin M. (2020). Surface-enhanced Raman spectroscopy for cancer immunotherapy applications: opportunities, challenges, and current progress in nanomaterial strategies. Nanomaterials, 10 (6) 1145, 1-15. doi: 10.3390/nano10061145
Sina, Abu Ali Ibn, Lin, Ting-Yun, Vaidyanathan, Ramanathan, Wang, Zhaoran, Dey, Shuvashis, Wang, Jing, Behren, Andreas, Wuethrich, Alain, Carrascosa, Laura G. and Trau, Matt (2020). Methylation dependent gold adsorption behaviour identifies cancer derived extracellular vesicular DNA. Nanoscale Horizons, 5 (9), 1317-1323. doi: 10.1039/d0nh00258e
Liao, Caizhi, Wuethrich, Alain and Trau, Matt (2020). A material odyssey for 3D nano/microstructures: two photon polymerization based nanolithography in bioapplications. Applied Materials Today, 19 100635, 100635. doi: 10.1016/j.apmt.2020.100635
Zhang, Zhen, Wang, Jing, Shanmugasundaram, Karthik Balaji, Yeo, Belinda, Möller, Andreas, Wuethrich, Alain, Lin, Lynlee L. and Trau, Matt (2020). Tracking drug-induced epithelial–mesenchymal transition in breast cancer by a microfluidic surface-enhanced raman spectroscopy immunoassay. Small, 16 (13) 1905614, e1905614. doi: 10.1002/smll.201905614
Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma
Wang, Jing, Wuethrich, Alain, Sina, Abu Ali Ibn, Lane, Rebecca E., Lin, Lynlee L., Wang, Yuling, Cebon, Jonathan, Behren, Andreas and Trau, Matt (2020). Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma. Science Advances, 6 (9) eaax3223, eaax3223. doi: 10.1126/sciadv.aax3223
Li, Junrong, Wuethrich, Alain, Dey, Shuvashi, Lane, Rebecca E., Sina, Abu A. I., Wang, Jing, Wang, Yuling, Puttick, Simon, Koo, Kevin M. and Trau, Matt (2020). The growing impact of micro/nanomaterial-based systems in precision oncology: translating “multiomics” technologies. Advanced Functional Materials, 30 (37) 1909306, 1909306. doi: 10.1002/adfm.201909306
Kumar, Aswin Raj, Shanmugasundaram, Karthik Balaji, Li, Junrong, Zhang, Zhen, Ibn Sina, Abu Ali, Wuethrich, Alain and Trau, Matt (2020). Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au–Ag alloy nanoboxes. RSC Advances, 10 (48), 28778-28785. doi: 10.1039/d0ra05032f
Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor
Wuethrich, Alain, Rajkumar, Aswin Raj, Shanmugasundaram, Karthik Balaji, Reza, Kamil K., Dey, Shuvashis, Howard, Christopher B., Sina, Abu Ali Ibn and Trau, Matt (2019). Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor. The Analyst, 144 (23), 6914-6921. doi: 10.1039/c9an01450k
Li, Junrong, Koo, Kevin M., Wang, Yuling and Trau, Matt (2019). Native MicroRNA targets trigger self‐assembly of nanozyme‐patterned hollowed nanocuboids with optimal interparticle gaps for plasmonic‐activated cancer detection. Small, 15 (50) 1904689, 1904689. doi: 10.1002/smll.201904689
Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing
Raftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g
Wang, Jing, Koo, Kevin M., Wang, Yuling and Trau, Matt (2019). Engineering state-of-the-art plasmonic nanomaterials for SERS-based clinical liquid biopsy applications. Advanced Science, 6 (23) 1900730, 1900730. doi: 10.1002/advs.201900730
Khondakar, Kamil Reza, Dey, Shuvashis, Wuethrich, Alain, Sina, Abu Ali Ibn and Trau, Matt (2019). Toward personalized cancer treatment: from diagnostics to therapy monitoring in miniaturized electrohydrodynamic systems. Accounts of Chemical Research, 52 (8) acs.accounts.9b00192, 2113-2123. doi: 10.1021/acs.accounts.9b00192
DNA methylation-based point-of-care cancer detection: challenges and possibilities
Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2019). DNA methylation-based point-of-care cancer detection: challenges and possibilities. Trends in Molecular Medicine, 25 (11), 955-966. doi: 10.1016/j.molmed.2019.05.014
Watching SERS glow for multiplex biomolecular analysis in the clinic: A review
Zeng, Yi, Koo, Kevin M., Trau, Matt, Shen, Ai-Guo and Hu, Ji-Ming (2019). Watching SERS glow for multiplex biomolecular analysis in the clinic: A review. Applied Materials Today, 15, 431-444. doi: 10.1016/j.apmt.2019.03.005
Merging new-age biomarkers and nanodiagnostics for precision prostate cancer management
Koo, Kevin M., Mainwaring, Paul N., Tomlins, Scott A. and Trau, Matt (2019). Merging new-age biomarkers and nanodiagnostics for precision prostate cancer management. Nature Reviews Urology, 16 (5), 302-317. doi: 10.1038/s41585-019-0178-2
A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells
Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt (2019). A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical, 284, 281-288. doi: 10.1016/j.snb.2018.12.099
Lane, Rebecca E., Korbie, Darren, Trau, Matt and Hill, Michelle M. (2019). Optimizing size exclusion chromatography for extracellular vesicle enrichment and proteomic analysis from clinically relevant samples. Proteomics, 19 (8) 1800156, 1800156. doi: 10.1002/pmic.201800156
Reading conformational changes in proteins with a new colloidal-based interfacial biosensing system
Ahmed, Mostak, Carrascosa, Laura G., Mainwaring, Paul and Trau, Matt (2019). Reading conformational changes in proteins with a new colloidal-based interfacial biosensing system. ACS Applied Materials and Interfaces, 11 (12) acsami.8b18269, 11125-11135. doi: 10.1021/acsami.8b18269
Wang, Jing, Anderson, Will, Li, Junrong, Lin, Lynlee L., Wang, Yuling and Trau, Matt (2019). A high-resolution study of in situ surface-enhanced Raman scattering nanotag behavior in biological systems. Journal of Colloid and Interface Science, 537, 536-546. doi: 10.1016/j.jcis.2018.11.035
PrimerROC: accurate condition-independent dimer prediction using ROC analysis
Johnston, Andrew D., Lu, Jennifer, Ru, Ke-lin, Korbie, Darren and Trau, Matt (2019). PrimerROC: accurate condition-independent dimer prediction using ROC analysis. Scientific Reports, 9 (1) 209, 209. doi: 10.1038/s41598-018-36612-9
Two-photon nanolithography of tailored hollow three-dimensional microdevices for biosystems
Liao, Caizhi, Anderson, Will, Antaw, Fiach and Trau, Matt (2019). Two-photon nanolithography of tailored hollow three-dimensional microdevices for biosystems. ACS Omega, 4 (1), 1401-1409. doi: 10.1021/acsomega.8b03164
Label-free detection of exosomes using surface plasmon resonance biosensor
Sina, A.A.I., Vaidyanathan, R., Wuethrich, A., Carrascosa, L. G. and Trau, M. (2019). Label-free detection of exosomes using surface plasmon resonance biosensor. Analytical and Bioanalytical Chemistry, 411 (7), 1311-1318. doi: 10.1007/s00216-019-01608-5
Phosphoprotein biosensors for monitoring pathological protein structural changes
Ahmed, Mostak, Koo, Kevin M., Mainwaring, Paul N., Carrascosa, Laura G. and Trau, Matt (2019). Phosphoprotein biosensors for monitoring pathological protein structural changes. Trends in Biotechnology, 38 (5), 519-531. doi: 10.1016/j.tibtech.2019.11.006
Tracking antigen specific T-cells: technological advancement and limitations
Dey, Shuvashis, Kamil Reza, K., Wuethrich, Alain, Korbie, Darren, Ibn Sina, Abu Ali and Trau, Matt (2019). Tracking antigen specific T-cells: technological advancement and limitations. Biotechnology Advances, 37 (1), 145-153. doi: 10.1016/j.biotechadv.2018.11.010
Dey, Shuvashis, Koo, Kevin, Wang, Zhaoran, Sina, Abu Ali Ibn, Wuethrich, Alain and Trau, Matt (2018). An integrated multi-molecular sensor for simultaneous BRAFV600E protein and DNA single point mutation detection in circulating tumour cells. Lab on a Chip, 19 (5), 738-748. doi: 10.1039/c8lc00991k
Koo, Kevin M., Dey, Shuvashis and Trau, Matt (2018). A sample-to-targeted gene analysis biochip for nanofluidic manipulation of solid-phase circulating tumor nucleic acid amplification in liquid biopsies. ACS Sensors, 3 (12) acssensors.8b01011, 2597-2603. doi: 10.1021/acssensors.8b01011
Sina, Abu Ali Ibn, Carrascosa, Laura G., Liang, Ziyu, Grewal, Yadveer S., Wardiana, Andri, Shiddiky, Muhammad J. A., Gardiner, Robert A., Samaratunga, Hemamali, Gandhi, Maher K., Scott, Rodney J., Korbie, Darren and Trau, Matt (2018). Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker. Nature Communications, 9 (1) 4915, 4915. doi: 10.1038/s41467-018-07214-w
A SERS microfluidic platform for targeting multiple soluble immune checkpoints
Reza, K. Kamil, Sina, Abu Ali Ibn, Wuethrich, Alain, Grewal, Yadveer S., Howard, Christopher B., Korbie, Darren and Trau, Matt (2018). A SERS microfluidic platform for targeting multiple soluble immune checkpoints. Biosensors and Bioelectronics, 126, 178-186. doi: 10.1016/j.bios.2018.10.044
"Mix-to-go" silver colloidal strategy for prostate cancer molecular profiling and risk prediction
Wang, Jing, Koo, Kevin M., Wang, Yuling and Trau, Matt (2018). "Mix-to-go" silver colloidal strategy for prostate cancer molecular profiling and risk prediction. Analytical Chemistry, 90 (21), 12698-12705. doi: 10.1021/acs.analchem.8b02959
Li, Junrong, Zhang, Guannan, Wang, Jing, Maksymov, Ivan S., Greentree, Andrew D., Hu, Jiming, Shen, Aiguo, Wang, Yuling and Trau, Matt (2018). Facile one-pot synthesis of nanodot-decorated gold-silver alloy nanoboxes for single-particle surface-enhanced raman scattering activity. ACS Applied Materials and Interfaces, 10 (38), 32526-32535. doi: 10.1021/acsami.8b10112
Reza, K. Kamil, Dey, Shuvashis, Wuethrich, Alain, Sina, Abu Ali Ibn, Korbie, Darren, Wang, Yuling and Trau, Matt (2018). Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay. Nanoscale, 10 (39), 18482-18491. doi: 10.1039/c8nr02886a
Li, Junrong, Wang, Jing, Grewal, Yadveer S, Howard, Christopher B, Raftery, Lyndon J, Mahler, Stephen, Wang, Yuling and Trau, Matt (2018). Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments. Analytical Chemistry, 90 (17) acs.analchem.8b02216, 10377-10384. doi: 10.1021/acs.analchem.8b02216
Koo, Kevin M., Wang, Jing, Richards, Renée S., Farrell, Aine, Yaxley, John W., Samaratunga, Hema, Teloken, Patrick E., Roberts, Matthew J., Coughlin, Geoffrey D., Lavin, Martin F., Mainwaring, Paul N., Wang, Yuling, Gardiner, Robert A. and Trau, Matt (2018). Design and clinical verification of surface-enhanced Raman spectroscopy diagnostic technology for individual cancer risk prediction. ACS Nano, 12 (8), 8362-8371. doi: 10.1021/acsnano.8b03698
Ahmed, Mostak, Carrascosa, Laura G, Wuethrich, Alain, Mainwaring, Paul and Trau, Matt (2018). An exosomal- and interfacial-biosensing based strategy for remote monitoring of aberrantly phosphorylated proteins in lung cancer cells. Biomaterials Science, 6 (9), 2336-2341. doi: 10.1039/c8bm00629f
Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges
Lane, R. E., Korbie, D., Hill, M. M. and Trau, M. (2018). Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges. Clinical and Translational Medicine, 7 (1) 14, 14. doi: 10.1186/s40169-018-0192-7
Koo, Kevin M., Dey, Shuvashis and Trau, Matt (2018). Amplification-free multi-RNA-type profiling for cancer risk stratification via alternating current electrohydrodynamic nanomixing. Small, 14 (17) 1704025, e1704025. doi: 10.1002/smll.201704025
Characterising the phenotypic evolution of circulating tumour cells during treatment
Tsao, Simon Chang-Hao, Wang, Jing, Wang, Yuling, Behren, Andreas, Cebon, Jonathan and Trau, Matt (2018). Characterising the phenotypic evolution of circulating tumour cells during treatment. Nature Communications, 9 (1) 1482, 1482. doi: 10.1038/s41467-018-03725-8
Koo, Kevin M., Dey, Shuvashis and Trau, Matt (2018). Adjustable fluidic nanomixing: amplification-free multi-RNA-type profiling for cancer risk stratification via alternating current electrohydrodynamic nanomixing (Small 17/2018). Small, 14 (17) 1870075. doi: 10.1002/smll.201870075
Wuethrich, Alain, Sina, Abu Ali Ibn, Ahmed, Mostak, Lin, Ting-Yun, Carrascosa, Laura G. and Trau, Matt (2018). Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers. Nanoscale, 10 (23), 10884-10890. doi: 10.1039/C7NR09496E
Maskless 3D Ablation of Precise Microhole Structures in Plastics Using Femtosecond Laser Pulses
Liao, Caizhi, Anderson, Will, Antaw, Fiach and Trau, Matt (2018). Maskless 3D Ablation of Precise Microhole Structures in Plastics Using Femtosecond Laser Pulses. ACS applied materials & interfaces, 10 (4), 4315-4323. doi: 10.1021/acsami.7b18029
Nucleic acid purification from plants, animals and microbes in under 30 seconds
Zou, Yiping, Mason, Michael Glenn, Wang, Yuling, Wee, Eugene, Turni, Conny, Blackall, Patrick J., Trau, Matt and Botella, Jose Ramon (2017). Nucleic acid purification from plants, animals and microbes in under 30 seconds. PLoS Biology, 15 (11) e2003916, e2003916. doi: 10.1371/journal.pbio.2003916
Li, Junrong, Wang, Jing, Wang, Yuling and Trau, Matt (2017). Simple and rapid colorimetric detection of melanoma circulating tumor cells using bifunctional magnetic nanoparticles. The Analyst, 142 (24), 4788-4793. doi: 10.1039/c7an01102d
Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing
Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2017). Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing. Microchemical Journal, 137, 231-237. doi: 10.1016/j.microc.2017.10.012
Ng, Benjamin Y. C., Wee, Eugene J. H., Woods, Kyra, Anderson, Will, Antaw, Fiach, Tsang, Hennes Z. H., West, Nicholas P. and Trau, Matt (2017). Isothermal point mutation detection: toward a first-pass screening strategy for multidrug-resistant tuberculosis. Analytical Chemistry, 89 (17), 9017-9022. doi: 10.1021/acs.analchem.7b01685
Ibn Sina, Abu Ali, Foster, Matthew Thomas, Korbie, Darren, Carrascosa, Laura G., Shiddiky, Muhammad J. A., Gao, Jing, Dey, Shuvashis and Trau, Matt (2017). A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity. Analyst, 142 (19), 3573-3578. doi: 10.1039/c7an00611j
Enabling miniaturised personalised diagnostics: from lab-on-a-chip to lab-in-a-drop
Koo, Kevin M., Wee, Eugene J. H., Wang, Yuling and Trau, Matt (2017). Enabling miniaturised personalised diagnostics: from lab-on-a-chip to lab-in-a-drop. Lab On a Chip, 17 (19), 3200-3220. doi: 10.1039/c7lc00587c
PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome
O'Leary, Valerie Bríd , Smida, Jan, Buske, Fabian Andreas, Carrascosa, Laura Garcia, Azimzadeh, Omid, Maugg, Doris, Hain, Sarah, Tapio, Soile, Heidenreich, Wolfgang, Kerr, James, Trau, Matt, Ovsepian, Saak Victor and Atkinson, Michael John (2017). PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome. Scientific Reports, 7 (1) 7163, 7163. doi: 10.1038/s41598-017-07295-5
Koo, Kevin M. , Carrascosa, Laura G. and Trau, Matt (2017). DNA-directed assembly of copper nanoblocks with inbuilt fluorescent and electrochemical properties: Application in simultaneous amplification-free analysis of multiple RNA species. Nano Research, 11 (2), 1-13. doi: 10.1007/s12274-017-1706-0
Ahmed, Mostak, Carrascosa, Laura G., Ibn Sina, Abu Ali, Zarate, Ester Marina, Korbie, Darren, Ru, Ke-lin, Shiddiky, Muhammad J. A., Mainwaring, Paul and Trau, Matt (2017). Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions. Biosensors and Bioelectronics, 91, 8-14. doi: 10.1016/j.bios.2016.12.012
Lu, Jennifer, Ru, Kelin, Candiloro, Ida, Dobrovic, Alexander, Korbie, Darren and Trau, Matt (2017). Evaluation of different oligonucleotide base substitutions at CpG binding sites in multiplex bisulfite-PCR sequencing. Scientific Reports, 7 (1) 45096, 45096. doi: 10.1038/srep45096
High-speed biosensing strategy for non-invasive profiling of multiple cancer fusion genes in urine
Koo, Kevin M., Wee, Eugene J. H. and Trau, Matt (2017). High-speed biosensing strategy for non-invasive profiling of multiple cancer fusion genes in urine. Biosensors and Bioelectronics, 89 (2), 715-720. doi: 10.1016/j.bios.2016.11.024
Electrohydrodynamic-induced SERS immunoassay for extensive multiplexed biomarker sensing
Reza, Khondakar Kamil, Wang, Jing, Vaidyanathan, Ramanathan, Dey, Shuvashis, Wang, Yuling and Trau, Matt (2017). Electrohydrodynamic-induced SERS immunoassay for extensive multiplexed biomarker sensing. Small, 13 (9) 1602902. doi: 10.1002/smll.201602902
Wang, Jing, Koo, Kevin M., Wee, Eugene J. H., Wang, Yuling and Trau, Matt (2017). A nanoplasmonic label-free surface-enhanced Raman scattering strategy for non-invasive cancer genetic subtyping in patient samples. Nanoscale, 9 (10), 3496-3503. doi: 10.1039/c6nr09928a
PrimerSuite: a high-throughput web-based primer design program for multiplex bisulfite PCR
Lu, Jennifer, Johnston, Andrew, Berichon, Philippe, Ru, Ke-lin, Korbie, Darren and Trau, Matt (2017). PrimerSuite: a high-throughput web-based primer design program for multiplex bisulfite PCR. Scientific Reports, 7 (1) 41328, 41328. doi: 10.1038/srep41328
Lau, Han Yih, Wu, Haoqi, Wee, Eugene J. H., Trau, Matt, Wang, Yuling and Botella, Jose R. (2017). Specific and sensitive isothermal electrochemical biosensor for plant pathogen DNA detection with colloidal gold nanoparticles as probes. Scientific Reports, 7 (1) 38896, 38896. doi: 10.1038/srep38896
Comprehensive evaluation of molecular enhancers of the isothermal exponential amplification reaction
Mok, Ellie, Wee, Eugene, Wang, Yuling and Trau, Matt (2016). Comprehensive evaluation of molecular enhancers of the isothermal exponential amplification reaction. Scientific Reports, 6 (1) 37837, 37837. doi: 10.1038/srep37837
Nanoyeast and other cell envelope compositions for protein studies and biosensor applications
Grewal, Yadveer S., Shiddiky, Muhammad J. A., Mahler, Stephen M., Cangelosi, Gerard A. and Trau, Matt (2016). Nanoyeast and other cell envelope compositions for protein studies and biosensor applications. ACS Applied Materials and Interfaces, 8 (45), 30649-30664. doi: 10.1021/acsami.6b09263
A DNA circuit for IsomiR detection
Connolly, Ashley R., Hirani, Rena, Ellis, Amanda V. and Trau, Matt (2016). A DNA circuit for IsomiR detection. ChemBioChem, 17 (22), 2172-2178. doi: 10.1002/cbic.201600452
Koo, Kevin M., McNamara, Benjamin, Wee, Eugene J. H., Wang, Yuling and Trau, Matt (2016). Rapid and sensitive fusion gene detection in prostate cancer urinary specimens by label-free surface-enhanced raman scattering. Journal of Biomedical Nanotechnology, 12 (9), 1798-1805. doi: 10.1166/jbn.2016.2294
Field demonstration of a multiplexed point-of-care diagnostic platform for plant pathogens
Lau, Han Yih, Wang, Yuling, Wee, Eugene J. H., Botella, Jose R. and Trau, Matt (2016). Field demonstration of a multiplexed point-of-care diagnostic platform for plant pathogens. Analytical Chemistry, 88 (16), 8074-8081. doi: 10.1021/acs.analchem.6b01551
Koo, Kevin M., Wee, Eugene J. H., Mainwaring, Paul N. and Trau, Matt (2016). A simple, rapid, low-cost technique for naked-eye detection of urine-isolated TMPRSS2:ERG gene fusion RNA. Scientific reports, 6 (1) 30722, 30722. doi: 10.1038/srep30722
Real time and label free profiling of clinically relevant exosomes
Sina, Abu Ali Ibn, Vaidyanathan, Ramanathan, Dey, Shuvashis, Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2016). Real time and label free profiling of clinically relevant exosomes. Scientific Reports, 6 (30460) 30460, 1-9. doi: 10.1038/srep30460
Magor, Graham W., Tallack, Michael R., Klose, Nathan M., Taylor, Debra, Korbie, Darren, Mollee, Peter, Trau, Matt and Perkins, Andrew C. (2016). Rapid molecular profiling of myeloproliferative neoplasms using targeted Exon Resequencing of 86 genes involved in JAK-STAT signaling and epigenetic regulation. Journal of Molecular Diagnostics, 18 (5), 707-718. doi: 10.1016/j.jmoldx.2016.05.006
Koo, Kevin M., Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2016). Amplification-free detection of gene fusions in prostate cancer urinary samples using mRNA-gold affinity interactions. Analytical Chemistry, 88 (13), 6781-6788. doi: 10.1021/acs.analchem.6b01182
Wee, Eugene J. H., Wang, Yuling, Simon, Chang-Hao Tsao and Trau, Matt (2016). Simple, sensitive and accurate multiplex detection of clinically important melanoma DNA mutations in circulating tumour DNA With SERS nanotags. Theranostics, 6 (10), 1506-1513. doi: 10.7150/thno.15871
Koo, Kevin, Wee, Eugene and Trau, Matt (2016). Colorimetric TMPRSS2-ERG gene fusion detection in prostate cancer urinary samples via recombinase polymerase amplification. Theranostics, 6 (9), 1415-1424. doi: 10.7150/thno.15250
Schmid, Peter, Pinder, Sarah E., Wheatley, Duncan, Macaskill, Jane, Zammit, Charles, Hu, Jennifer, Price, Robert, Bundred, Nigel, Hadad, Sirwan, Shia, Alice, Sarker, Shah-Jalal, Lim, Louise, Gazinska, Patrycja, Woodman, Natalie, Korbie, Darren, Trau, Matt, Mainwaring, Paul, Gendreau, Steven, Lackner, Mark R., Derynck, Mika, Wilson, Timothy R., Butler, Hannah, Earl, Gemma, Parker, Peter, Purushotham, Arnie and Thompson, Alastair (2016). Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer. Journal of Clinical Oncology, 34 (17), 1987-1994. doi: 10.1200/JCO.2015.63.9179
Biosensing made easy with PEG-targeted bi-specific antibodies
Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A
Electric field induced isolation, release, and recapture of tumor cells
Dey, Shuvashis, Vaidyanathan, Ramanathan, Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2016). Electric field induced isolation, release, and recapture of tumor cells. ACS Sensors, 1 (4), 399-405. doi: 10.1021/acssensors.5b00157
Simple isothermal strategy for multiplexed, rapid, sensitive, and accurate miRNA detection
Wee, Eugene J. H. and Trau, Matt (2016). Simple isothermal strategy for multiplexed, rapid, sensitive, and accurate miRNA detection. ACS Sensors, 1 (6), 670-675. doi: 10.1021/acssensors.6b00105
Yadav, Sharda, Carrascosa, Laura G., Sina, Abu A. I., Shiddiky, Muhammad J. A., Hill, Michelle M. and Trau, Matt (2016). Electrochemical detection of protein glycosylation using lectin and protein-gold affinity interactions. Analyst, 141 (8), 2356-2361. doi: 10.1039/c6an00528d
Wong, Nicholas C., Pope, Bernard J., Candiloro, Ida L., Korbie, Darren, Trau, Matt, Wong, Stephen Q., Mikeska, Thomas, Zhang, Xinmin Z, Pitman, Mark, Eggers, Stefanie, Doyle, Stephen R and Dobrovic, Alexander (2016). MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing. BMC Bioinformatics, 17 (1) 98, 98.1-98.14. doi: 10.1186/s12859-016-0950-8
Capture and on-chip analysis of melanoma cells using tunable surface shear forces
Tsao, Simon Chang-Hao, Vaidyanathan, Ramanathan, Dey, Shuvashis, Carrascosa, Laura G., Christophi, Christopher, Cebon, Jonathan, Shiddiky, Muhammad J. A., Behren, Andreas and Trau, Matt (2016). Capture and on-chip analysis of melanoma cells using tunable surface shear forces. Scientific Reports, 6 (1) 19709, 19709.1-19709.10. doi: 10.1038/srep19709
Koo, Kevin M., Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2016). Poly(A) extensions of miRNAs for amplification-free electrochemical detection on screen-printed gold electrodes. Analytical Chemistry, 88 (4), 2000-2005. doi: 10.1021/acs.analchem.5b04795
Wang, Yuling, Wee, Eugene J. H. and Trau, Matt (2016). Accurate and sensitive total genomic DNA methylation analysis from sub-nanogram input with embedded SERS nanotags. Chemical Communications, 52 (17), 3560-3563. doi: 10.1039/C6CC00547K
Koo, Kevin M., Wee, Eugene J. H., Mainwaring, Paul N., Wang, Yuling and Trau, Matt (2016). Toward precision medicine: a cancer molecular subtyping nano-trategy for RNA biomarkers in tumor and urine. Small, 12 (45), 6233-6242. doi: 10.1002/smll.201602161
Ng, Benjamin Y. C., Wee, Eugene J. H., West, Nicholas P. and Trau, Matt (2015). Naked-eye colorimetric and electrochemical detection of Mycobacterium tuberculosis—toward rapid screening for active case finding. ACS Sensors, 1 (2), 173-178. doi: 10.1021/acssensors.5b00171
Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat
Wong, Nicholas C., Pope, Bernard J., Candiloro, Ida, Korbie, Darren, Trau, Matt, Wong, Stephen Q., Mikeska, Thomas, van Denderen, Bryce J. W., Thompson, Erik W., Eggers, Stefanie, Doyle, Stephen R. and Dobrovic, Alexander (2015). Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat. Gigascience, 4 (1) 55, 55.1-55.8. doi: 10.1186/s13742-015-0098-x
Vaidyanathan, Ramanathan, Rauf, Sakandar, Grewal, Yadveer S., Spadafora, Lauren J., Shiddiky, Muhammad J. A., Cangelosi, Gerard A. and Trau, Matt (2015). Enhancing protein capture using a combination of nanoyeast single-chain fragment affinity reagents and alternating current electrohydrodynamic forces. Analytical Chemistry, 87 (23), 11673-11681. doi: 10.1021/acs.analchem.5b02490
Vaidyanathan, Ramanathan, Dey, Shuvashis, Carrascosa, Laura G., Shiddiky, Muhammad J.A. and Trau, Matt (2015). Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces. Biomicrofluidics, 9 (061501) 061501, 061501. doi: 10.1063/1.4936300
Ng, Benjamin Y. C., Xiao, Wei, West, Nicholas P., Wee, Eugene J. H., Wang, Yuling and Trau, Matt (2015). Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold Nanoparticles. Analytical Chemistry, 87 (20), 10613-10618. doi: 10.1021/acs.analchem.5b03121
Wee, Eugene J. H., Ngo, Thu Ha and Trau, Matt (2015). A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation. Scientific Reports, 5 (Art No.: 15028) 15028, 15028. doi: 10.1038/srep15028
Ng, Benjamin Y.C., Wee, Eugene J. H., West, Nicholas P. and Trau, Matt (2015). Rapid DNA detection of Mycobacterium tuberculosis-towards single cell sensitivity in point-of-care diagnosis. Scientific Reports, 5 (1) 15027, 15027.1-15027.7. doi: 10.1038/srep15027
DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer
Stone, Andrew, Zotenko, Elena, Locke, Warwick J., Korbie, Darren, Millar, Ewan K. A., Pidsley, Ruth, Stirzaker, Clare, Graham, Peter, Trau, Matt, Musgrove, Elizabeth A., Nicholson, Robert I., Gee, Julia M. W. and Clark, Susan J. (2015). DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer. Nature Communications, 6 (1) 7758, 7758.1-7758.9. doi: 10.1038/ncomms8758
Wee, Eugene J. H., Ngo, Thu Ha and Trau, Matt (2015). Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs. Clinical Epigenetics, 7 (1) 65, 65. doi: 10.1186/s13148-015-0100-6
DNA-bare gold affinity interactions: mechanism and applications in biosensing
Koo, Kevin M., Sina, Abu A. I., Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2015). DNA-bare gold affinity interactions: mechanism and applications in biosensing. Analytical Methods, 7 (17), 1-13. doi: 10.1039/c5ay01479d
Wang, Yuling, Vaidyanathan, Ramanathan, Shiddiky, Muhammad J. A. and Trau, Matt (2015). Enabling rapid and specific surface enhanced raman scattering immunoassay using nano-scaled surface shear forces. ACS Nano, 9 (6), 6354-6362. doi: 10.1021/acsnano.5b01929
Anderson, Will, Lane, Rebecca, Korbie, Darren and Trau, Matt (2015). Observations of tunable resistive pulse sensing for exosome analysis: improving system sensitivity and stability. Langmuir, 31 (23), 6577-6587. doi: 10.1021/acs.langmuir.5b01402
Structural characterization of nanoyeast single-chain fragment variable affinity reagents
Grewal, Yadveer S., Shiddiky, Muhammad J. A., Spadafora, Lauren J., Cangelosi, Gerard A. and Trau, Matt (2015). Structural characterization of nanoyeast single-chain fragment variable affinity reagents. The Journal of Physical Chemistry Part C: Nanomaterials, Interfaces and Hard Matter, 119 (22), 12674-12680. doi: 10.1021/acs.jpcc.5b01234
Vaidyanathan, Ramanathan, van Leeuwen, Lara Michelle, Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt (2015). A multiplexed device based on tunable nanoshearing for specific detection of multiple protein biomarkers in serum. Scientific Reports, 5 (1) 9756, 9756.1-9756.7. doi: 10.1038/srep09756
O'Leary, Valerie Brid, Ovsepian, Saak Victor, Carrascosa, Laura Garcia, Buske, Fabian Andreas, Radulovic, Vanja, Niyazi, Maximilian, Moertl, Simone, Trau, Matt and Atkinson, Michael John (2015). PARTICLE, a triplex-forming long ncRNA, regulates locus-specific methylation in response to low-dose irradiation. Cell Reports, 11 (3), 474-485. doi: 10.1016/j.celrep.2015.03.043
Multiplex bisulfite PCR resequencing of clinical FFPE DNA
Korbie, Darren, Lin, Erica, Wall, David, Nair, Shalima S., Stirzaker, Clare, Clark, Sue J. and Trau, Matt (2015). Multiplex bisulfite PCR resequencing of clinical FFPE DNA. Clinical Epigenetics, 7 (28) 28, 1-11. doi: 10.1186/s13148-015-0067-3
Stirzaker, Clare, Zotenko, Elena, Song, Jenny Z., Qu, Wenja, Nair, Shalima, Locke, Warwick J., Stone, Andrew Stone, Armstrong, Nicola J., Robinson, Mark D., Dobrovic, Alexander, Avery-Kiejda, Kelly A., Peters, Kate M., French, Juliet D., Stein, Sandra, Korbie, Darren J., Trau, Matt, Forbes, John F., Scott, Rodney J., Brown, Melissa A., Francis, Glenn D. and Clark, Susan J. (2015). Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value. Nature Communications, 6 (5899) 5899, 1-11. doi: 10.1038/ncomms6899
Wee, E. J. H., Lau, H. Y., Botella, J. and Trau, M. (2015). Re-purposing bridging flocculation for on-site, rapid, qualitative DNA detection in resource-poor settings. Chemical Communications, 51 (27), 5828-5831. doi: 10.1039/C4CC10068A
Lane, Rebecca E., Korbie, Darren, Anderson, Will, Vaidyanathan, Ramanathan and Trau, Matt (2015). Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing. Scientific Reports, 5 (1) 7639, 7639.1-7639.7. doi: 10.1038/srep07639
Wang, Yuling, Wee, Eugene J. H. and Trau, Matt (2015). Highly sensitive DNA methylation analysis at CpG resolution by surface-enhanced Raman scattering via ligase chain reaction. Chemical Communications, 51 (54), 10953-10956. doi: 10.1039/c5cc03921e
Vaidyanathan, Ramanathan, Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt (2014). Tuneable surface shear forces to physically displace nonspecific molecules in protein biomarker detection. Biosensors and Bioelectronics, 61, 184-191. doi: 10.1016/j.bios.2014.03.061
Molecular inversion probe: a new tool for highly specific detection of plant pathogens
Lau, Han Yih, Palanisamy, Ramkumar, Trau, Matt and Botella, Jose R. (2014). Molecular inversion probe: a new tool for highly specific detection of plant pathogens. PLoS One, 9 (10) e111182, e111182.1-e111182.9. doi: 10.1371/journal.pone.0111182
Vaidyanathan, Ramanathan, Naghibosadat, Maedeh, Rauf, Sakandar, Korbie, Darren, Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2014). Detecting exosomes specifically: a multiplexed device based on alternating current electrohydrodynamic induced nanoshearing. Analytical Chemistry, 86 (22), 11125-11132. doi: 10.1021/ac502082b
Koo, Kevin M., Sina, Abu Ali Ibn, Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2014). eMethylsorb: rapid quantification of DNA methylation in cancer cells on screen-printed gold electrodes. Analyst, 139 (23), 6178-6184. doi: 10.1039/c4an01641f
DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing
Wee, Eugene J. H., Rauf, Sakandar, Shiddiky, Muhammad J. A., Dobrovic, Alexander and Trau, Matt (2014). DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing. Clinical Chemistry, 61 (1), 163-171. doi: 10.1373/clinchem.2014.227546
Sina, Abu Ali Ibn, Howell, Sidney, Carrascosa, Laura G., Rauf, Sakandar, Shiddiky, Muhammad J. A . and Trau, Matt (2014). eMethylsorb: electrochemical quantification of DNA methylation at CpG resolution using DNA-gold affinity interactions. Chemical Communications, 50 (86), 13153-13156. doi: 10.1039/C4CC06732K
Wang, Yuling, Rauf, Sakandar, Grewal, Yadveer S., Spadafora, Lauren J., Shiddiky, Muhammad J. A., Cangelosi, Gerard A., Schlücker, Sebastian and Trau, Matt (2014). Duplex microfluidic SERS detection of pathogen antigens with nanoyeast single-chain variable fragments. Analytical Chemistry, 86 (19), 9930-9938. doi: 10.1021/ac5027012
Electrochemical detection of glycan and protein epitopes of glycoproteins in serum
Shah, Alok K., Hill, Michelle M., Shiddiky, Muhammad J. A. and Trau, Matt (2014). Electrochemical detection of glycan and protein epitopes of glycoproteins in serum. Analyst, 139 (22), 5970-5976. doi: 10.1039/C4AN00781F
Enzyme catalysis: evolution made easy
Wee, Eugene J. H. and Trau, Matt (2014). Enzyme catalysis: evolution made easy. Nature Chemistry, 6 (9), 756-757. doi: 10.1038/nchem.2046
Measuring whole genome methylation via oxygen channelling chemistry
Wee, Eugene J. H. and Trau, Matt (2014). Measuring whole genome methylation via oxygen channelling chemistry. Chemical Communications, 50 (74), 10894-10896. doi: 10.1039/C4CC04623D
Microdevices for detecting locus-specific DNA methylation at CpG resolution
Koo, Kevin M., Wee, Eugene, Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt (2014). Microdevices for detecting locus-specific DNA methylation at CpG resolution. Biosensors and Bioelectronics, 56, 278-285. doi: 10.1016/j.bios.2014.01.029
Grewal, Yadveer S., Shiddiky, Muhammad J. A., Spadafora, Lauren J., Cangelosi, Gerard A. and Trau, Matt (2014). Nano-yeast–scFv probes on screen-printed gold electrodes for detection of Entamoeba histolytica antigens in a biological matrix. Biosensors and Bioelectronics, 55, 417-422. doi: 10.1016/j.bios.2013.12.043
Electrohydrodynamic removal of non-specific colloidal adsorption at electrode interfaces
Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt (2014). Electrohydrodynamic removal of non-specific colloidal adsorption at electrode interfaces. Chemical Communications, 50 (37), 4813-4815. doi: 10.1039/C4CC01357C
Vaidyanathan, Ramanathan, Rauf, Sakandar, Dray, Eloïse, Shiddiky, Muhammad J. A. and Trau, Matt (2014). Alternating current electrohydrodynamics induced nanoshearing and fluid micromixing for specific capture of cancer cells. Chemistry: A European Journal, 20 (13), 3724-3729. doi: 10.1002/chem.201304590
Carrascosa, Laura G., Sina, Abu Ali Ibn, Palanisamy, Ramkumar, Sepulveda, Borja, Otte, Marinus A., Rauf, Sakandar, Shiddiky, Muhamad J. A. and Trau, Matt (2014). Molecular inversion probe-based SPR biosensing for specific, label-free and real-time detection of regional DNA methylation. Chemical Communications, 50 (27), 3585-3588. doi: 10.1039/C3CC49607D
Vaidyanathan, Ramanathan, Shiddiky, Muhammad J. A., Rauf, Sakandar, Dray, Eloise, Tay, Zhikai and Trau, Matt (2014). Tuneable “Nano-Shearing”: a physical mechanism to displace nonspecific cell adhesion during rare cell detection. Analytical Chemistry, 86 (4), 2042-2049. doi: 10.1021/ac4032516
Shiddiky, Muhammad J. A., Vaidyanathan, Ramanathan, Rauf, Sakandar, Tay, Zhikay and Trau, Matt (2014). Molecular nanoshearing: an innovative approach to shear off molecules with AC-induced nanoscopic fluid flow. Scientific Reports, 4 (1) 3716, 3716.1-3716.7. doi: 10.1038/srep03716
Methylsorb: a simple method for quantifying DNA methylation using DNA-gold affinity interactions
Sina, Abu Ali Ibn, G. Carrascosa, Laura, Palanisamy, Ramkumar, Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt (2014). Methylsorb: a simple method for quantifying DNA methylation using DNA-gold affinity interactions. Analytical Chemistry, 86 (20), 10179-10185. doi: 10.1021/ac502214z
Anderson, Will, Kozak, Darby, Coleman, Victoria A., Jämting, Asa K. and Trau, Matt (2013). A comparative study of submicron particle sizing platforms: accuracy, precision and resolution analysis of polydisperse particle size distributions. Journal of Colloid and Interface Science, 405, 322-330. doi: 10.1016/j.jcis.2013.02.030
Wee, Eugene J. H., Rauf, Sakandar, Koo, Kevin, Shiddiky, Muhammad J. A. and Trau, Matt (2013). mu-eLCR: a microfabricated device for electrochemical detection of DNA base changes in breast cancer cell lines. Lab on a Chip, 13 (22), 4385-4391-4385-4391. doi: 10.1039/C3LC50528F
"Drill and fill" lithography for controlled fabrication of 3D platinum electrodes
Rauf, Sakandar, Muhammad J. A. Shiddiky and Trau, Matt (2013). "Drill and fill" lithography for controlled fabrication of 3D platinum electrodes. Sensors and Actuators B: Chemical, 185, 543-547. doi: 10.1016/j.snb.2013.05.040
Accurate detection of methylated cytosine in complex methylation landscapes
Palanisamy, Ramkumar, Connolly, Ashley R. and Trau, Matt (2013). Accurate detection of methylated cytosine in complex methylation landscapes. Analytical Chemistry, 85 (14), 6575-6579. doi: 10.1021/ac3031948
Grewal, Yadveer S., Shiddiky, Muhammad J. A., Gray, Sean A., Weigel, Kris M., Cangelosi, Gerard A. and Trau, Matt (2013). Label-free electrochemical detection of an Entamoeba histolytica antigen using cell-free yeast-scFv probes. Chemical Communications, 49 (15), 1551-1553. doi: 10.1039/c2cc38882k
Rauf, Sakandar, Shiddiky, Muhammad J. A., Trau, Matt and Dimitrov, Krassen (2013). "Drill and fill" lithography: fabrication of platinum electrodes and their use in label-free immunosensing. RSC Advances, 3 (13), 4189-4192. doi: 10.1039/c3ra21900c
eLCR: electrochemical detection of single DNA base changes via ligase chain reaction
Wee, Eugene J. H., Shiddiky, Muhammad J. A., Brown, Melissa A. and Trau, Matt (2012). eLCR: electrochemical detection of single DNA base changes via ligase chain reaction. Chemical Communications, 48 (98), 1214-1216. doi: 10.1039/C2CC35841G
Shiddiky, Muhammad J. A., Kithva, Prakash H., Kozak, Darby and Trau, Matt (2012). An electrochemical immunosensor to minimize the nonspecific adsorption and to improve sensitivity of protein assays in human serum. Biosensors and Bioelectronics, 38 (1), 132-137. doi: 10.1016/j.bios.2012.05.014
Tuning particle velocity and measurement sensitivity by changing pore sensor dimensions
Kozak, Darby, Anderson, Will and Trau, Matt (2012). Tuning particle velocity and measurement sensitivity by changing pore sensor dimensions. Chemistry Letters, 41 (10), 1134-1136. doi: 10.1246/cl.2012.1134
Kozak, Darby, Anderson, Will, Vogel, Robert, Chen, Shaun, Antaw, Fiach and Trau, Matt (2012). Simultaneous size and zet-potential measurements of individual nanoparticles in dispersion using size-tunable pore sensors. Acs Nano, 6 (8), 6990-6997. doi: 10.1021/nn3020322
Shiddiky, Muhammad J. A., Rauf, Sakandar, Kithva, Prakash H. and Trau, Matt (2012). Graphene/quantum dot bionanoconjugates as signal amplifiers in stripping voltammetric detection of EpCAM biomarkers. Biosensors and Bioelectronics, 35 (1), 251-257. doi: 10.1016/j.bios.2012.02.057
Shiddiky, Muhammad J. A., Kithva, Prakash H., Rauf, Sakandar and Trau, Matt (2012). Femtomolar detection of a cancer biomarker protein in serum with ultralow background current by anodic stripping voltammetry. Chemical Communications, 48 (51), 6411-6413. doi: 10.1039/c2cc32810k
Modeling Elastic Pore Sensors for Quantitative Single Particle Sizing
Kozak, Darby, Anderson, Will, Grevett, Matthew and Trau, Matt (2012). Modeling Elastic Pore Sensors for Quantitative Single Particle Sizing. The Journal of Physical Chemistry C: Nanomaterials, Interfaces and Hard Matter, 116 (15), 8554-8561. doi: 10.1021/jp211845t
Kozak, Darby, Anderson, Will, Vogel, Robert and Trau, Matt (2011). Advances in resistive pulse sensors: Devices bridging the void between molecular and microscopic detection. Nano Today, 6 (5), 531-545. doi: 10.1016/j.nantod.2011.08.012
Sensitive quantification of somatic mutations using molecular inversion probes
Hirani, Rena, Connolly, Ashley R., Putral, Lisa, Dobrovic, Alexander and Trau, Matt (2011). Sensitive quantification of somatic mutations using molecular inversion probes. Analytical Chemistry, Articles ASAP (21), 8215-8221. doi: 10.1021/ac2019409
Multiplatform comparison of multiplexed bead arrays using HPV genotyping as a test case
Corrie, Simon R., Feng, Qinghua, Blair, Tiffany, Hawes, Stephen E., Kiviat, Nancy B. and Trau, Matt (2011). Multiplatform comparison of multiplexed bead arrays using HPV genotyping as a test case. Cytometry Part A, 79A (9), 713-719. doi: 10.1002/cyto.a.21109
Characterisation of amine functionalised poly(3-hydroxybuturate-co-3-hydroxyvalerate) surfaces
Luk, Jing Zhong, Rondeau, Elisabeth, Trau, Matt, Cooper-White, Justin and Grondahl, Lisbeth (2011). Characterisation of amine functionalised poly(3-hydroxybuturate-co-3-hydroxyvalerate) surfaces. Polymer, 52 (15), 3251-3258. doi: 10.1016/j.polymer.2011.05.048
Protein resistance of dextran and dextran-poly(ethylene glycol) copolymer films
Kozak, D, Chen, A, Bax, J and Trau, M (2011). Protein resistance of dextran and dextran-poly(ethylene glycol) copolymer films. Biofouling, 27 (5), 497-503. doi: 10.1080/08927014.2011.584618
Rapid DNA detection by beacon-assisted detection amplification
Connolly, Ashley R and Trau, Matt (2011). Rapid DNA detection by beacon-assisted detection amplification. Nature Protocols, 6 (6), 772-778. doi: 10.1038/nprot.2011.326
Quantitative sizing of nano/microparticles with a tunable elastomeric pore sensor
Vogel, Robert, Willmott, Geoff, Kozak, Darby, Roberts, Seth G., Anderson, Will, Groenewegen, Linda, Glossop, Ben, Barnett, Anne, Turner, Ali and Trau, Matt (2011). Quantitative sizing of nano/microparticles with a tunable elastomeric pore sensor. Analytical Chemistry, 83 (9), 3499-3506. doi: 10.1021/ac200195n
Epiallele quantification using molecular inversion probes
Palanisamy, Ramkumar, Connolly, Ashley R. and Trau, Matt (2011). Epiallele quantification using molecular inversion probes. Analytical Chemistry, 83 (7), 2631-2637. doi: 10.1021/ac103016n
Corrie, Simon R., Sova, Pavel, Feng, Qinghua, Blair, Tiffany, Kiviat, Nancy B. and Trau, Matt (2011). Bisulfite-free analysis of 5MeC-binding proteins and locus-specific methylation density using a microparticle-based flow cytometry assay. Analyst, 136 (4), 688-691. doi: 10.1039/c0an00790k
Pradal, Clementine, Kithva, Prakash, Martin, Darren, Trau, Matt and Grøndahl, Lisbeth (2011). Improvement of the wet tensile properties of nanostructured hydroxyapatite and chitosan biocomposite films through hydrophobic modification. Journal of Materials Chemistry, 21 (7), 2330-2337. doi: 10.1039/c0jm03080e
Xue, Ying, O'Mara, Megan L., Surawski, Peter P. T., Trau, Matt and Mark, Alan E. (2011). Effect of poly(ethylene glycol) (PEG) spacers on the conformational properties of small peptides: A molecular dynamics study. Langmuir, 27 (1), 296-303. doi: 10.1021/la103800h
Development of encoded particle-polymer arrays for the accelerated screening of antifouling layers
Kozak, Darby, Kithva, Prakash, Bax , Jacinda, Surawski, Peter P. T., Monteiro, Michael J. and Trau, Matt (2011). Development of encoded particle-polymer arrays for the accelerated screening of antifouling layers. Chemical Communications, 47 (34), 9687-9689. doi: 10.1039/c1cc13571f
Roberts, G. Seth, Kozak, Darby, Anderson, Will, Broom, Murray F., Vogel, Robert and Trau, Matt (2010). Tunable nano/micropores for particle detection and discrimination: Scanning ion occlusion spectroscopy. Small, 6 (23), 2653-2658. doi: 10.1002/smll.201001129
Use of tunable nanopore blockade rates to investigate colloidal dispersions
Willmott, G. R., Vogel, R., Yu, S. S. C., Groenewegen, L. G., Roberts, G. S., Kozak, D., Anderson, W. and Trau, M. (2010). Use of tunable nanopore blockade rates to investigate colloidal dispersions. Journal of Physics: Condensed Matter, 22 (45) 454116, 454116-1-454116-11. doi: 10.1088/0953-8984/22/45/454116
Considerations of solid-phase DNA amplification
Palanisamy, Ramkumar, Connolly, Ashley R. and Trau, Matt (2010). Considerations of solid-phase DNA amplification. Bioconjugate Chemistry, 21 (4), 690-695. doi: 10.1021/bc900491s
Isothermal detection of DNA by beacon-assisted detection amplification
Connolly, Ashley R. and Trau, Matt (2010). Isothermal detection of DNA by beacon-assisted detection amplification. Angewandte Chemie (International Edition), 49 (15), 2720-2723. doi: 10.1002/anie.200906992
Tissue transplantation by stealth — Coherent alginate microcapsules for immunoisolation
Leung, Andy, Nielsen, Lars K., Trau, Matt and Timmins, Nicholas E. (2010). Tissue transplantation by stealth — Coherent alginate microcapsules for immunoisolation. Biochemical Engineering Journal, 48 (3), 337-347. doi: 10.1016/j.bej.2009.10.007
Marcon, Lionel, Battersby, Bronwyn J., Ruhmann, Andreas, Ford, Kym, Daley, Matthew, Lawrie, Gwendolyn A. and Trau, Matt (2010). 'On-the-fly' optical encoding of combinatorial peptide libraries for profiling of protease specificity. Molecular Biosystems, 6 (1), 225-233. doi: 10.1039/b909087h
Kithva, P., Grondahl, L., Martin, D. and Trau, M. (2010). Biomimetic synthesis and tensile properties of nanostructured high volume fraction hydroxyapatite and chitosan biocomposite films. Journal of Materials Chemistry, 20 (2), 381-389. doi: 10.1039/b914798e
Quantitative considerations for suspension array assays
Connolly, A.R., Palanisamy, R. and Trau, M. (2010). Quantitative considerations for suspension array assays. Journal of Biotechnology, 145 (1), 17-22. doi: 10.1016/j.jbiotec.2009.10.004
Corrie, Simon, Sova, Pavel, Lawrie, Gwen, Battersby, Bronwyn, Kiviat, Nancy and Trau, Matt (2009). Development of a multiplexed bead-based assay for detection of DNA methylation in cancer-related genes. Molecular Biosystems, 5 (3), 262-268. doi: 10.1039/b813077a
Antifouling Surface Layers for Improved Signal-to-Noise of Particle-Based Immunoassays
Chen, A., Kozak, D., Battersby, B.J., Forrest, R.M., Scholler, N., Urban, N. and Trau, M. (2009). Antifouling Surface Layers for Improved Signal-to-Noise of Particle-Based Immunoassays. Langmuir, 25 (23), 13510-13515. doi: 10.1021/la903148n
Kithva, Prakash Hariram, Grondahl, Lisbeth, Kumar, Rajendra, Martin, Darren and Trau, Matt (2009). An organic matrix-mediated processing methodology to fabricate hydroxyapatite based nanostructured biocomposites. Nanoscale, 1 (2), 229-232. doi: 10.1039/b9nr00062c
Trau, M. and Battersby, B. (2009). Biosensing cancer biomarkers. The Chemical Engineer (820), 30-31.
Synthesis and Application of FRET Nanoparticles in the Profiling of a Protease
Marcon, L., Spriet, C., Meehan, T.D., Battersby, B.J., Lawrie, G.A., Heliot, L. and Trau, M. (2009). Synthesis and Application of FRET Nanoparticles in the Profiling of a Protease. Small, 5 (18), 2053-2056. doi: 10.1002/smll.200801887
Jack, Kevin S., Velayudhan, Shiny, Luckman, Paul, Trau, Matt, Grondahl, Lisbeth and Cooper-White, Justin (2009). The fabrication and characterization of biodegradable HA/PHBV nanoparticle-polymer composite scaffolds. Acta Biomaterialia, 5 (7), 2567-2667. doi: 10.1016/j.actbio.2009.03.017
Kozak, D., Surawski, P., Thoren, K.M., Lu, C.Y., Marcon, L. and Trau, M. (2009). Improving the Signal-to-Noise Performance of Molecular Diagnostics with PEG-Lysine Copolymer Dendrons. BIOMACROMOLECULES, 10 (2), 360-365. doi: 10.1021/bm8011314
Noohom, Wadcharawadee, Jack, Kevin S., Martin, Darren and Trau, Matt (2009). Understanding the roles of nanoparticle dispersion and polymer crystallinity in controlling the mechanical properties of HA/PHBV nanocomposites. Biomedical Materials, 4 (015003), 015003. doi: 10.1088/1748-6041/4/1/015003
Leung, Andy, Trau, Matt and Nielsen, Lars Keld (2009). Assembly of multilayer PSS/PAH membrane on coherent alginate/PLO microcapsule for long-term graft transplantation. Journal of Biomedical Materials Research Part A, 88A (1), 226-237. doi: 10.1002/jbm.a.31891
Surawski, PPT, Battersby, BJ, Vogel, R, Lawrie, G and Trau, M (2009). Modification and optimization of organosilica microspheres for peptide synthesis and microsphere-based immunoassays. Molecular Biosystems, 5 (8), 826-831. doi: 10.1039/b817080k
Rai, B., Grondahl, L. and Trau, M. (2008). Combining chemistry and biology to create colloidally stable bionanohydroxyapatite particles: Toward load-bearing bone applications. Langmuir, 24 (15), 7744-7749. doi: 10.1021/la8005212
Chen, Annie, Kozak, Darby, Battersby, Bronwyn J. and Trau, Matt (2008). Particle-by-particle quantification of protein adsorption onto poly(ethylene glycol) grafted surfaces. Biofouling, 24 (4), 267-273. doi: 10.1080/08927010802058471
Corrie, S. R., Lawrie, G. A., Battersby, B. J., Ford, K., Rühmann, A., Koehler, K., Sabath, D. E. and Trau, M. (2008). Quantitative data analysis methods for bead-based DNA hybridization assays using generic flow cytometry platforms. Cytometry. Part A, 73A (5), 467-476. doi: 10.1002/cyto.a.20534
Surawski, Peter P. T., Battersby, Bronwyn J., Lawrie, Gwendolyn A., Ford, Kym, Ruhmann, Andreas, Marcon, Lionel, Kozak, Darby and Trau, Matt (2008). Flow cytometric detection of proteolysis in peptide libraries synthesised on optically encoded supports. Molecular Biosystems, 4 (7), 774-778. doi: 10.1039/b718513h
Rai, B., Noohom, W., Kithva, P.H., Grondahl, L. and Trau, M. (2008). Bionanohydroxyapatite/Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composites with improved particle dispersion and superior mechanical properties. Chemistry of Materials, 20 (8), 2802-2808. doi: 10.1021/cm703045u
Profiling protein-surface interactions of multicomponent suspensions via flow cytometry
Kozak, Darby, Chen, Annie and Trau, Matt (2008). Profiling protein-surface interactions of multicomponent suspensions via flow cytometry. Langmuir, 24 (4), 1204-1211. doi: 10.1021/la701847x
Marcon, L., Kozak, D., Battersby, B.J., Chappell, K., Fairlie, D., Young, P.R. and Trau, M. (2008). A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases. Analytical Biochemistry, 2008 (376), 151-153. doi: 10.1016/j.ab.2008.01.034
A structural study of hybrid organosilica materials for colloid-based DNA biosensors
Corrie, Simon R., Vogel, Robert, Keen, Imelda, Jack, Kevin, Kozak, Darby, Lawrie, Gwendolyn A., Battersby, Bronwyn J., Fredericks, Peter and Trau, Matt (2008). A structural study of hybrid organosilica materials for colloid-based DNA biosensors. Journals of Materials Chemistry, 18 (5), 523-529. doi: 10.1039/b714309e
Leung, A.H.M., Lawrie, G.A., Nielsen, L.K. and Trau, M. (2008). Synthesis and characterization of alginate/poly-L-ornithine/alginate microcapsules for local immunosuppression. Journal of Microencapsulation, 25 (6), 387-398. doi: 10.1080/02652040802008857
Toward colloid-based biosensors for SNP genotyping and personalised medicine applications
Johnston, Angus P. R., Lawrie, Gwendolyn A., Battersby, Bronwyn J., Corrie, Simon R. and Trau, Matt (2008). Toward colloid-based biosensors for SNP genotyping and personalised medicine applications. International Journal of Nanotechnology, 5 (2-3), 299-317. doi: 10.1504/IJNT.2008.016920
Fluorescent organosilica micro- and nanoparticles with controllable size
Vogel, R., Surawski, P.T., Littleton, B. N., Miller, C., Lawrie, G. A., Battersby, B. J. and Trau, M. (2007). Fluorescent organosilica micro- and nanoparticles with controllable size. Journal of Colloid and Interface Science, 310 (1), 144-150. doi: 10.1016/j.jcis.2007.01.092
Keen, I., Raggatt, L.J., Cool, S.M., Nurcombe, V., Fredericks, P., Trau, M. and Grondahl, L. (2007). Investigations into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) surface properties causing delayed osteoblast growth. Journal of Biomaterials Science-polymer Edition, 18 (9), 1101-1123. doi: 10.1163/156856207781554046
Cool, SM, Kenny, B, Wu, A, Nurcombe, V, Trau, M, Cassady, AI and Grondahl, L (2007). Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composite biomaterials for bone tissue regeneration: In vitro performance assessed by osteoblast proliferation, osteoclast adhesion and resorption, and macrophage proinflammatory response. Journal of Biomedical Materials Research Part A, 82A (3), 599-610. doi: 10.1002/jbm.a.31174
Jack, K.S., Vizcarra, T.G. and Trau, M. (2007). Characterization and surface properties of amino-acid-modified, carbonate-containing hydroxyapatite particles. Langmuir, 23 (24), 12233-12242. doi: 10.1021/la701848c
Optically encoded particles and their applications in multiplexed biomedical assays
Battersby, B.J. and Trau, M. (2007). Optically encoded particles and their applications in multiplexed biomedical assays. Australian Journal of Chemistry, 60 (5), 343-353. doi: 10.1071/CH07006
Refractometry of organosilica microspheres
Seet, K. Y. T., Vogel, R., Nieminen, T. A., Knoner, G., Rubinsztein-Dunlop, H., Trau, M. and Zvyagin, A. V. (2007). Refractometry of organosilica microspheres. Applied Optics, 46 (9), 1554-1561. doi: 10.1364/AO.46.001554
Johnston, Angus P. R., Battersby, Bronwyn J., Lawrie, Gwendolyn A., Lambert, Lynette K. and Trau, Matt (2006). A mechanism for forming large fluorescent organo-silica particles: Potential supports for combinatorial synthesis. Chemistry of Materials, 18 (26), 6163-6169. doi: 10.1021/cm0526260
Keen, I., Broota, P., Rintoul, L., Fredericks, P., Trau, M. and Grondahl, L. (2006). Introducing amine functionalities on a poly(3-hydroxybutyrate-co-3-hydroxyvalerate) surface: Comparing the use of ammonia plasma treatment and ethylenediamine aminolysis. Biomacromolecules, 7 (2), 427-434. doi: 10.1021/bm050497a
Multiplexed microsphere diagnostic tools in gene expression applications: Factors and futures
Lawrie, Gwendolyn A., Robinson, Jodie, Corrie, Simon, Ford, Kym, Battersby, Bronwyn J. and Trau, Matt (2006). Multiplexed microsphere diagnostic tools in gene expression applications: Factors and futures. International Journal Nanomedicine, 1 (2), 195-201. doi: 10.2147/nano.2006.1.2.195
Quantitative analysis and characterization of biofunctionalized fluorescent silica particles
Corrie, Simon R., Lawrie, Gwendolyn A. and Trau, Matt (2006). Quantitative analysis and characterization of biofunctionalized fluorescent silica particles. Langmuir, 22 (6), 2731-2737. doi: 10.1021/la052433r
Wu, Andy C. K., Grondahl, Lisbeth, Jack, Kevin S., Foo, Michelle X., Trau, Matt, Hume, David A. and Cassady, Alan I. (2006). Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate). Biomaterials, 27 (27), 4715-4725. doi: 10.1016/j.biomaterials.2006.05.010
Lawrie, Gwendolyn, Grondahl, Lisbeth, Battersby, Bronwyn, Keen, Imelda, Lorentzen, Michael, Surawski, Peter and Trau, Matt (2006). Tailoring surface properties to build colloidal diagnostic devices: Controlling interparticle associations. Langmuir, 22 (1), 497-505. doi: 10.1021/la051833b
Functionalized organosilica microspheres via a novel emulsion-based route
Miller, CR, Vogel, R, Surawski, PPT, Jack, KS, Corrie, SR and Trau, M (2005). Functionalized organosilica microspheres via a novel emulsion-based route. Langmuir, 21 (21), 9733-9740. doi: 10.1021/la0514112
Biomolecular screening with novel organosilica microspheres
Miller, C. R., Vogel, R., Surawski, P. P. T., Corrie, S. R., Ruhmann, A. and Trau, M. (2005). Biomolecular screening with novel organosilica microspheres. Chemical Communications, 2005 (38), 4783-4785. doi: 10.1039/b509503d
Emulsion strategies in the microencapsulation of cells: Pathways to thin coherent membranes
Leung, A, Ramaswamy, Y, Munro, P, Lawrie, G, Nielsen, L and Trau, M (2005). Emulsion strategies in the microencapsulation of cells: Pathways to thin coherent membranes. Biotechnology And Bioengineering, 92 (1), 45-53. doi: 10.1002/bit.20597
Grondahl, Lisbeth, Chandler-Temple, Adrienne and Trau, Matt (2005). Polymeric grafting of acrylic acid onto poly(3-hydroxybutyrate-co-3-hydroxyvalerate): Surface functionalization for tissue engineering applications. Biomacromolecules, 6 (4), 2197-2203. doi: 10.1021/bm050127m
Porous functionalised silica particles: a potential platform for biomolecular screening
Johnston, APR, Battersby, BJ, Lawrie, GA and Trau, M (2005). Porous functionalised silica particles: a potential platform for biomolecular screening. Chemical Communications, 7 (-), 848-850. doi: 10.1039/b415376f
Bioballs: manipulating colloidal nanostructures for biotechnology applications
Lawrie, G. A., Battersby, B. J. and Trau, M. (2004). Bioballs: manipulating colloidal nanostructures for biotechnology applications. Applied Nanoscience, 1 (1), 17-24.
Postsynthesis stabilization of free-standing mesoporous silica films
Vogel, R, Dobe, C, Whittaker, A, Edwards, G, Riches, JD, Harvey, M, Trau, M and Meredith, P (2004). Postsynthesis stabilization of free-standing mesoporous silica films. Langmuir, 20 (7), 2908-2914. doi: 10.1021/la035788o
Lawrie, G. A., Battersby, B. J., Grondahl, L. and Trau, M. (2003). Advances in encoding of colloids for combinatorial libraries: Applications in genomics, proteomics and drug discovery. Current Pharmaceutical Biotechnology, 4 (6), 439-449. doi: 10.2174/1389201033377256
Mesoporous dye-doped titanium dioxide for micro-optoelectronic applications
Vogel, Robert, Meredith, Paul, Kartini, Indriana, Harvey, Michael, Riches, Jamie D., Bishop, Alexis, Heckenberg, Norman, Trau, Matt and Rubinsztein-Dunlop, Halina (2003). Mesoporous dye-doped titanium dioxide for micro-optoelectronic applications. ChemPhysChem, 4 (6), 595-603. doi: 10.1002/cphc.200200494
Analysis of RNA-protein interactions by flow cytometry
Brodsky, AS, Johnston, AP, Trau, M and Silver, PA (2003). Analysis of RNA-protein interactions by flow cytometry. Current Opinion In Molecular Therapeutics, 5 (3), 235-240.
Analysis of the phase behavior of the aqueous poly(ethylene glycol)-Ficoll system
Croll, T., Munro, P., Winzor, D. J., Trau, M. and Nielsen, L. K. (2003). Analysis of the phase behavior of the aqueous poly(ethylene glycol)-Ficoll system. Biotechnology Progress, 19 (4), 1269-1273. doi: 10.1021/bp025711a
Micropatterned lead zirconium titanate thin films
Vartuli, JS, Ozenbas, M, Chun, CM, Trau, M and Aksay, IA (2003). Micropatterned lead zirconium titanate thin films. Journal of Materials Research, 18 (5), 1259-1265. doi: 10.1557/JMR.2003.0173
Quantitative prediction of phase diagrams for polymer partitioning in aqueous two-phase systems
Croll, T., Munro, P. D., Winzor, D. J., Trau, M. and Nielsen, L. K. (2003). Quantitative prediction of phase diagrams for polymer partitioning in aqueous two-phase systems. Journal of Polymer Science Part B-polymer Physics, 41 (5), 437-443. doi: 10.1002/polb.10402
Lawrie, GA, Battersby, BJ and Trau, M (2003). Synthesis of optically complex core-shell colloidal suspensions: Pathways to multiplexed biological screening. Advanced Functional Materials, 13 (11), 887-896. doi: 10.1002/adfm.200304390
Dimer-to-monomer transformation of Rhodamine 6G in aqueous PEO−PPO−PEO block copolymer solutions
Vogel, R., Harvey, M., Edwards, G., Meredith, P., Heckenberg, N., Trau, M. and Rubinsztein-Dunlop, H. (2002). Dimer-to-monomer transformation of Rhodamine 6G in aqueous PEO−PPO−PEO block copolymer solutions. Macromolecules, 35 (6), 2063-2070. doi: 10.1021/ma010995l
Novel miniaturized systems in high-throughput screening
Battersby, BJ and Trau, M (2002). Novel miniaturized systems in high-throughput screening. Trends In Biotechnology, 20 (4), 167-173. doi: 10.1016/S0167-7799(01)01898-4
Optical barcoding of colloidal suspensions: applications in genomics, proteomics and drug discovery
Battersby, Bronwyn J., Lawrie, Gwendolyn A., Johnston, Angus P. R. and Trau, Matt (2002). Optical barcoding of colloidal suspensions: applications in genomics, proteomics and drug discovery. Chemical Communications, 2 (14), 1435-1441. doi: 10.1039/b200038p
Chemistry for the future at the IUPAC World Chemistry Congress
Trau, M (2001). Chemistry for the future at the IUPAC World Chemistry Congress. Australian Journal of Chemistry, 54 (9-10), 549-549. doi: 10.1071/CH02028
Multi-fluorescent silica colloids for encoding large combinatorial libraries
Matthews, D. C., Grondahl, L., Battersby, B. J. and Trau, M. (2001). Multi-fluorescent silica colloids for encoding large combinatorial libraries. Australian Journal of Chemistry, 54 (9-10), 649-656. doi: 10.1071/CH01120
Novel colloidal materials for high-throughput screening applications in drug discovery and genomics
Trau, M and Battersby, BJ (2001). Novel colloidal materials for high-throughput screening applications in drug discovery and genomics. Advanced Materials, 13 (12-13), 975-+. doi: 10.1002/1521-4095(200107)13:12/13<975::AID-ADMA975>3.0.CO;2-#
Optical encoding of microbeads for gene screening: alternatives to microarrays
Battersby, BJ, Lawrie, GA and Trau, M (2001). Optical encoding of microbeads for gene screening: alternatives to microarrays. Drug Discovery Today, 6 (12), S19-S26. doi: 10.1016/s1359-6446(01)00149-0
Encoding combinatorial libraries: A novel application of fluorescent silica colloids
Grondahl, Lisbeth, Battersby, Bronwyn J., Bryant, Darryn and Trau, Matt (2000). Encoding combinatorial libraries: A novel application of fluorescent silica colloids. Langmuir, 16 (25), 9709-9715. doi: 10.1021/la000995z
Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry
Battersby, Bronwyn J., Bryant, Darryn, Meutermans, Wim, Matthews, Daniel, Smythe, Mark L. and Trau, Matt (2000). Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry. Journal of the American Chemical Society, 122 (9), 2138-2139. doi: 10.1021/ja993634i
Microscopic patterning of orientated mesoscopic silica through guided growth
Trau, M., Yao, N., Kim, E, Xia, Y, Whitesides, G. M. and Aksay, I. A. (1997). Microscopic patterning of orientated mesoscopic silica through guided growth. Nature, 390 (6661), 674-676. doi: 10.1038/37764
Assembly of colloidal crystals at electrode interfaces
Trau, M., Saville, D. A. and Aksay, I. A. (1997). Assembly of colloidal crystals at electrode interfaces. Langmuir, 13 (24), 6375-6381. doi: 10.1021/la970568u
Mesoporous silicate film growth at the air-water interface: direct observation by x-ray reflectivity
Brown, A. S., Holt, S. A., Dam, Thien, Trau, M. and White, J. W. (1997). Mesoporous silicate film growth at the air-water interface: direct observation by x-ray reflectivity. Langmuir, 13 (24), 6363-6365. doi: 10.1021/la970832j
Biomimetic pathways for assembling inorganic thin films
Aksay, I. A., Trau, M., Manne, S., Honma, I., Yao, N., Zhou, L., Fenter, P., Eisenberger, P. M. and Gruner, S. M. (1996). Biomimetic pathways for assembling inorganic thin films. Science, 273 (5277), 892-898. doi: 10.1126/science.273.5277.892
Field-induced layering of colloidal crystals
Trau, M., Saville, D. A. and Aksay, I. A. (1996). Field-induced layering of colloidal crystals. Science, 272 (5262), 706-709. doi: 10.1126/science.272.5262.706
Pattern formation in nonaqueous colloidal dispersions via electrohydrodynamic flow
Trau, M., Sankaran, S., Saville, D. A. and Aksay, I. A. (1995). Pattern formation in nonaqueous colloidal dispersions via electrohydrodynamic flow. Langmuir, 11 (12), 4665-4672. doi: 10.1021/la00012a015
Electric-field-induced pattern formation in colloidal dispersions
Trau, M., Sankaran, S., Saville, D. A. and Aksay, I. A. (1995). Electric-field-induced pattern formation in colloidal dispersions. Nature, 374 (6521), 437-439. doi: 10.1038/374437a0
Trau, Mathias, Grieser, Franz, Healy, Thomas W. and White, Lee R. (1994). Evanescent wave spectroscopy: application to the study of the spatial distribution of charged groups on an adsorbed polyelectrolyte at the silica/water interface. Journal of the Chemical Society, Faraday Transactions, 90 (9), 1251-1259. doi: 10.1039/FT9949001251
Trau, Mathias, Grieser, Franz, Healy, Thomas W. and White, Lee R. (1992). Investigation by evanescent waves of the charge and conformation of an adsorbed polyelectrolyte at the silica/aqueous solution interface. Langmuir, 8 (10), 2349-2353. doi: 10.1021/la00046a001
An ellipsometric study of thin films on silica plates formed by alkylchlorosilylation reagents
Trau, Mathias, Murray, Brent Stuart, Grant, Kasenya and Grieser, Franz (1992). An ellipsometric study of thin films on silica plates formed by alkylchlorosilylation reagents. Journal of Colloid and Interface Science, 148 (1), 182-189. doi: 10.1016/0021-9797(92)90126-7
The entry of free radicals into polystyrene latex particles
Adams, Mary E., Trau, Mathias, Gilbert, Robert G., Napper, Donald H. and Sangster, David F. (1988). The entry of free radicals into polystyrene latex particles. Australian Journal of Chemistry, 41 (12), 1799-1813. doi: 10.1071/CH9881799
Koo, K., Wee, E., Mainwaring, P., Wang, Y. and Trau, M. (2016). Towards precision medicine: A cancer molecular subtyping nano-strategy for RNA biomarkers in tumor and urine. 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich Germany, November 29 - December 2 2016. United Kingdom: Pergamon. doi: 10.1016/S0959-8049(16)32680-6
Enabling rapid and specific SERS immunoassay using nano-scaled surface shear forces
Vaidyanathan, Ramanathan, Wang, Yuling, Shiddiky, Muhammad J. A. and Trau, Matt (2015). Enabling rapid and specific SERS immunoassay using nano-scaled surface shear forces. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, 25-29 October 2015. Washington, DC USA: Chemical and Biological Microsystems Society.
Wee, Eugene J. H., Koo, Kevin M., Mainwaring, Paul N. and Trau, Mattias (2015). Towards rapid and cost-effective point-of-care detection of TMPRSS2:ERG fusion transcripts in urine via a novel methodology. Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL United States, 29 May-02 June 2015. Alexandria, VA United States: American Society of Clinical Oncology.
Vaidyanathan, Ramanathan, van Leeuwen, Lara Michelle, Rauf, Sakandar, Shiddiky, Muhammad J. A and Trau, Matt (2014). A Multiplex Device Based on Tunable Nanoshear Forces for Highly Specific Detection of Multiple Protein Biomarkers. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, San Antonio, TX United States, 26-30 October 2014. San Antonio, TX United States: MicroTAS.
Shiddiky, Muhammad J, Vaidyanathan, Ramanathan, Naghibosadat, Maedeh, Rauf, Sakandar, Korbie, Darren, Carrascosa, Laura G and Trau, Matt (2014). Detecting Exosomes Specifically: a Microfluidic Approach Based on Alternating Current Electrohydrodynamic Induced Nanoshearing. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, San Antonio, TX United States, 26-30 October 2014. San Antonio, TX United States: MicroTAS.
Methylsorb: A Simple Method for Quantifying DNA Methylation Using DNA-gold Affinity Interactions
Shiddiky, Muhammad J, Sina, Abu Ali Ibn, Carracosa, Laura G, Palanisamy, Ramkumar, Rauf, Sakandar and Trau, Matt (2014). Methylsorb: A Simple Method for Quantifying DNA Methylation Using DNA-gold Affinity Interactions. 8th International Conference on Electrical and Computer Engineering, Dhaka, Bangladesh, 20-22 December 2014. New York, NY United States: I E E E. doi: 10.1109/ICECE.2014.7027002
Tunable Nano-Shearing: Some New Ideas for Capturing Ctcs and Rare Molecules From Blood
Trau, Matt (2014). Tunable Nano-Shearing: Some New Ideas for Capturing Ctcs and Rare Molecules From Blood. COSA's 41st Annual Scientific Meeting. Joining Forces - Accelerating Progress, Melbourne, VIC Australia, 2-4 December 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12304
Shiddiky, Muhammad J. A., Vaidyanathan, Ramanathan, Rauf, Sakandar, Tay, Zhikai and Trau, Matt (2013). Tuneable "nanoshearing": an innovative mechanism for the accurate and specific capture of rare cancer cells. μTAS 2013: The 17th International Conference on Miniaturised Systems for Chemistry and Life Sciences (MicroTAS 2013), Freiburg, Germany, 27-31 October, 2013. San Diego, CA, USA: The Chemical and Biological Microsystems Society (CBMS).
Understanding and control of mechanical properties of HA/PHBV nanocomposites for bone applications
Noohom, Wadcharawadee, Jack, Kevin S., Martin, Darren J. and Trau, Matt (2009). Understanding and control of mechanical properties of HA/PHBV nanocomposites for bone applications. 8th World Biomaterials Conference, Amsterdam, Netherlands, 28 May- 1 June, 2008. Red Hook, N.Y. U.S.A.: Curran Associates, Inc..
Corrie, S. R., Lawrie, G. A., Battersby, B. J., Ford, K., Ruhmann, A., Koehler, K., Sabath, D. E. and Trau, M. (2007). Quantitative data analysis methods for bead-based DNA hybridization assays using generic flow cytometry platforms. Association for Molecular Pathology 2007 Annual Meeting, The Hyatt Regency Century Plaza Hotel, Los Angeles, California, 7-10 November, 2007. Bethesda, MD: American Society for Investigative Pathology and the Association of Molecular Pathology.
Wu, A. C., Grondahl, L., Jack, K. S., Trau, M. and Cassady, A. I. (2006). Minimization of pro-inflammatory responses of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for use in bone tissue engineering. 28th Australasian Polymer Symposium & Australian Society for Biomat, Rotorua, 5-9th February, 2006.
Organosilica particles for DNA screening applications
Corrie, Simon, Lawrie, Gwen, Battersby, Bronwyn and Trau, Matt (2006). Organosilica particles for DNA screening applications. ICONN 2006: International Conference On Nanoscience and Nanotechnology, Brisbane, QLD, Australia, 3-7 July, 2006. Piscataway, NJ, USA: IEEE. doi: 10.1109/ICONN.2006.340599
Tailoring poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for bone tissue engineering
Grondahl, L, Keen, I, Raggatt, L, Chandler-Temple, A. F., Cool, S M and Trau, M (2006). Tailoring poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for bone tissue engineering. 28th Australasian Polymer Symposium & Aust Society for Biomat, Rotorua, 5-9 Feb, 2006.
Poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) supports in vitro osteogenesis
Kumarasuriyar, A., Jackson, R. A., Grondahl, L., Trau, M., Nurcombe, V. and Cool, S. M. (2005). Poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) supports in vitro osteogenesis. New Rochelle: Mary Ann Liebert Inc. doi: 10.1089/ten.2005.11.1281
Keen, I., Raggatt, L., Cool, S. M., Nurcombe, V., Fredericks, P., Trau, M. and Grondahl, L. (2005). Response of osteoblast cells to the surface properties of Poly(3-hydroxybutyrate-co-hydroxyvalerate) PHBV. 2nd ARC Centre For Functional Nanomaterials Annual Conference, Maroochydore, Nov, 2005.
Development and in vitro testing of a biodegradable bone scaffold
Grondahl, L., Lutton, C. J., Kenny, B., Cool, S. M., Cassady, A.I. and Trau, M. (2004). Development and in vitro testing of a biodegradable bone scaffold. 7th World Biomaterials Congress, Sydney, May, 2004.
In vitro analysis of a bioactive, biodegradable material for bone repair
Kumarasuriyar, A., Jackson, R., Grondahl, L., Trau, M., Nurcombe, V. and Cool, S. M. (2004). In vitro analysis of a bioactive, biodegradable material for bone repair. 7th World Biomaterials Congress, Sydney, May, 2004.
Influence of solvent on the surface properties of PHBV solvent cast films
Keen, I., Grondahl, L., Raggatt, L., Fredericks, P.M., Nurcombe, V., Trau, M. and Cool, S. M. (2004). Influence of solvent on the surface properties of PHBV solvent cast films. 27th Australasian Polymer Symposium, Adelaide, Nov, 2004.
Surface modification of PHBV for bone tissue engineering
Keen, I., Grondahl, L., Cool, S. M., Nurcombe, V. and Trau, M. (2004). Surface modification of PHBV for bone tissue engineering. 7th World Biomaterials Congress, Sydney, May, 2004.
Biodegradable polyester materials: Uses in bone regeneration
Grondahl, L., Chandler-Temple, A. F., Luong-Van, E. K., Riding, A. S., Kumarasuriyar, A., Kenny, B., Cool, S. M., Nurcombe, V., Whittaker, A. K., Cassady, I.A. and Trau, M. (2003). Biodegradable polyester materials: Uses in bone regeneration. 26th Australian Polymer Conference, Noosa, July, 2003.
Surface modification for PHBV for enhanced biocompatibility
Chandler-Temple, A. F., Grondahl, L., Trau, M., Cool, S. M. and Nurcombe, V. (2003). Surface modification for PHBV for enhanced biocompatibility. 13th Annual Conference of Australian Society for Biomaterials, Brisbane, March, 2003.
Lawrie, G. A., Battersby, B. J., Grondahl, L., Tam, T., Lorentzen, M. and Trau, M. (2003). To stick or not to stick: Surface modification of colloidal nanoparticles to control interparticle associations. 11th International Conference on Surface & Colloid Science, Brazil, September, 2003.
Nanostructured biomaterials: a novel approach to artificial bone implants
Lutton, C, Read, J and Trau, M (2001). Nanostructured biomaterials: a novel approach to artificial bone implants. Australia: CSIRO Publishing. doi: 10.1071/CH01118
Field-induced two- and three-dimensional colloidal crystals
Trau, M., Saville, D. A. and Aksay, I. A. (1996). Field-induced two- and three-dimensional colloidal crystals. 1995 MRS Fall Meeting & Exhibit, Boston, MA, USA, 27 November-1 December, 1995. Washington, DC, United States: American Chemical Society.
Sensors. Special issue: "Biomarkers and Nanosensors: New Approaches for Biology and Medicine"
Sensors. Special issue: "Biomarkers and Nanosensors: New Approaches for Biology and Medicine". (2012). 12 (SI 7)
Digital chemistry and catalysis: redefining reactions in confined systems
(2024–2028) ARC Australian Laureate Fellowships
(2023–2027) University of Sydney
An integrated nano-bioengineered chip for enhanced molecular evolution
(2022–2025) ARC Discovery Projects
nanoIMPAC: Monitoring immune toxicities and tumour immune evasion in lung cancer
(2022–2025) Cancer Australia
(2022–2023) Metro South Hospital and Health Service
(2021–2028) Evolution Mining Limited
Single molecule sensing on nanopillars: Reading complex molecular circuits
(2021–2023) ARC Discovery Projects
The amplification of DNA from environmental metazoan cells (enCells)
(2021–2023) CSIRO
Cannabis genetic marker development for the breeding of medicinal cannabis varieties
(2021–2022) CannaPacific Pty Ltd
(2020–2022) Queensland Institute of Medical Research
(2019–2022) University of Newcastle
(2018–2022) NHMRC Project Grant
DNA exhibits new self-assembled structures due to clustered DNA methylation
(2018–2021) ARC Discovery Projects
Genomics markers in breast cancer
(2018–2021) Queen Mary University of London
(2018) Metro North Hospital and Health Service
(2018) Queensland University of Technology
Rapid detection and quantitation of Campylobacter jejuni/coli in processing.
(2016–2019) Queensland Department of Agriculture and Fisheries
AC electrohydrodynamics in microfluidic devices
(2016–2018) UniQuest Pty Ltd
Trapping and Watching Biomolecular Complexes near Nanopores
(2016–2018) ARC Discovery Projects
(2016–2017) Queen Mary University of London
Does prostatic manipulation result in increased numbers and clusters of circulating tumour cells?
(2016) Royal Brisbane and Women's Hospital Foundation
Exosome and Bio/Nanoparticle Characterisation Facility
(2016) UQ Major Equipment and Infrastructure
(2014–2016) ARC Discovery Projects
Optimisation of the single drop genomics assay to detect food pathogens
(2014–2015) Australian Centre for International Agricultural Research
Enabling Clinical Epigenetic Diagnostics: The Next Generation of Personalized Breast Cancer Care
(2013–2019) National Breast Cancer Foundation
Accelerated Molecular Probe Pipeline (NIH grant administered by the University of Washington)
(2012–2014) University of Washington (Seattle)
(2012) UQ Major Equipment and Infrastructure
Mass spectrometer for biomolecule discovery, structural analysis and quantification.
(2011) UQ Major Equipment and Infrastructure
Fabrication and Testing Facilites for Mono-Dispersed Nanoporous Spheres in Advanced Bio-applications
(2010) UQ Major Equipment and Infrastructure
Accelerated Molecular Probe Pipeline
(2009–2012) Seattle Biomedical Research Institute
(2008–2013) National Breast Cancer Foundation
(2008–2011) Cancer Australia
(2008) UQ Major Equipment and Infrastructure
Advanced environmental and process analysis facility
(2008) UQ Major Equipment and Infrastructure
Automated Microvave Reactor for Polymer Chemistry, Materials Development and Nanotechnology
(2008) UQ Major Equipment and Infrastructure
(2008) UQ Major Equipment and Infrastructure
(2008) UQ Major Equipment and Infrastructure
Novel Nanotechnology Platforms for Disease Biomarker Diagnostics
(2007–2010) Queensland Government Smart State National and International Research Alliances Program
Early detection of breast cancer via nanoscaled biomarker discovery and diagnostics
(2007) National Breast Cancer Foundation
(2006) ARC Linkage Infrastructure, Equipment and Facilities
Small Angle Scattering Facility for the Materials and Biological Sciences
(2006) ARC Linkage Infrastructure, Equipment and Facilities
Multiplexed Molecular Reading of Protein Associations via Nanoscaled Devices
(2005–2007) ARC Discovery Projects
Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing
(2004–2009) ARC Federation Fellowships
(2004–2006) University of Technology Sydney
(2003–2010) ARC Centres of Excellence
DEVELOPMENT OF A NOVEL BIOMATERIAL FOR BONE TISSUE ENGINEERING
(2003) ARC Discovery Projects
Designed nanostructures for Ti02-based solar cells
(1999–2001) Sustainable Technologies Australia
Designed nanostructures for Ti02-based solar cells
(1999–2001) Sustainable Technologies Australia
Self-assembled membranes for protection of foreign tissue transplants
(1999–2001) ARC Australian Research Council (Large grants)
Biomaterials and Nanotechnology Research Initiative
(1999) UQ Foundation Research Excellence Awards - DVC(R) Funding
Designed nanostructured materials through bi-inspired assembly
(1999) UQ External Support Enabling Grant
Rapid DNA sequencing by hybridization of a patterned colloidal array
(1998–2000) ARC Australian Research Council (Large grants)
Mechanistic Studies of the Anti-HIV drug FP-21399
(1998) UQ Foundation
Febrication of nanostructured ceramic materials and devices
(1997) ARC Australian Research Council (Small grants)
Rapid DNA sequencing by hybridization of a patterned colloidal array
(1997) University of Queensland New Staff Research Grant
Bioengineering yeast nanofragment affinity probes for dengue diagnostics
Doctor Philosophy — Principal Advisor
Other advisors:
Single-nanoparticle upconversion nanolasers for probing biological systems
Doctor Philosophy — Principal Advisor
Other advisors:
Radiopharmaceutical on Demand ¿ Reinventing the Infrastructure of Nuclear Medicine Therapy
Doctor Philosophy — Principal Advisor
Other advisors:
A novel technology for the measurement of protein phosphoryation
Doctor Philosophy — Principal Advisor
Other advisors:
An integrated nano-bioengineered chip for enhanced molecular evolution
Doctor Philosophy — Principal Advisor
Other advisors:
PhageExpress - A novel approach to proteomic highthroghput screening
Doctor Philosophy — Principal Advisor
Other advisors:
Single molecule sensing on nanopillars: Reading complex molecular circuits
Doctor Philosophy — Principal Advisor
Other advisors:
A nano-engineered chip to help manage acute and long-haul COVID-19 patients
Doctor Philosophy — Principal Advisor
Other advisors:
Utilising extracellular vesicles for the diagnosis of lung cancer.
Doctor Philosophy — Principal Advisor
Other advisors:
Monitoring molecular heterogeneity in extracellular vesicles and understanding cellular communications during treatment procedure
Doctor Philosophy — Principal Advisor
Other advisors:
The investigation of microglial activation in brain cancer and brain metastasis by an integrated nano-sensor
Doctor Philosophy — Associate Advisor
Other advisors:
A potential pan-cancer diagnostic utilizing DNA methylation landscapes
Doctor Philosophy — Associate Advisor
Other advisors:
Harnessing nanotechnology to unravel the phenotypic heterogeneity of extracellular vesicles
Doctor Philosophy — Associate Advisor
Other advisors:
A protein phosphorylation mapping tool for monitoring tyrosine kinase inhibition therapy in cancer patients
Doctor Philosophy — Associate Advisor
Other advisors:
Surface engineering of nanoyeast
Doctor Philosophy — Associate Advisor
Other advisors:
Novel Nanotechnology Platforms for Cancer Diagnostics
(2023) Doctor Philosophy — Principal Advisor
Other advisors:
(2023) Doctor Philosophy — Principal Advisor
Other advisors:
A Bioinformatics Approach Towards an Integrative Multi-Omics Analysis of Pan Cancer Biomarkers
(2022) Doctor Philosophy — Principal Advisor
Other advisors:
Driving Nanomaterial-Based Systems towards "Multiomics" Detection for Precision Oncology
(2021) Doctor Philosophy — Principal Advisor
Nanoparticle tracking and trapping using computerised feedback control
(2021) Doctor Philosophy — Principal Advisor
Probing cancer epigenetics with highly multiplexed PCR and targeted resequencing
(2021) Doctor Philosophy — Principal Advisor
Other advisors:
(2021) Doctor Philosophy — Principal Advisor
Other advisors:
(2020) Doctor Philosophy — Principal Advisor
Extracellular Vesicles as Circulating Breast Cancer Biomarkers
(2020) Doctor Philosophy — Principal Advisor
Other advisors:
SERS-Microfluidic Assay for Rapid Profiling of Cancer Biomarkers
(2020) Doctor Philosophy — Principal Advisor
Miniaturized Techniques for Rare Cell Isolation, Release and Molecular Analysis
(2019) Doctor Philosophy — Principal Advisor
Point-of-care tuberculosis diagnostics: Meeting global needs through innovative nanotechnologies
(2019) Doctor Philosophy — Principal Advisor
Other advisors:
Unravelling pathologic protein phosphorylation with interfacial biosensing: a new approach for cancer detection and therapy monitoring
(2019) Doctor Philosophy — Principal Advisor
Advancing Gene Fusion Detection towards Personalized Cancer Nanodiagnostics
(2018) Doctor Philosophy — Principal Advisor
Bioinformatic Tools and Applications for Analysis of DNA Methylation
(2017) Master Philosophy — Principal Advisor
Other advisors:
Detecting DNA methylation at the gold interface: A gateway towards next generation cancer diagnostics
(2017) Doctor Philosophy — Principal Advisor
(2016) Doctor Philosophy — Principal Advisor
Nanoyeast Antibody Fragments: Engineering the Next Generation of Molecular Diagnostics
(2015) Doctor Philosophy — Principal Advisor
Towards comprehensive DNA methylation analysis using molecular inversion probes
(2014) Doctor Philosophy — Principal Advisor
Development of a Multiplexed Particle-based Immunoassay for Biomarker Screening
(2010) Doctor Philosophy — Principal Advisor
Dual Purpose Colloids for Peptide Synthesis and Bio-Assay Applications
(2008) Doctor Philosophy — Principal Advisor
Other advisors:
DEVEOPMENT A LOAD-BEARING NANOCOMPOSITE BIODEGRADABLE SCAFFOLD FOR USE IN BONE TISSUE ENGINEERING
(2007) Doctor Philosophy — Principal Advisor
Other advisors:
ENCODING MICROSPHERE-BASED LIBRARIES USING FLOW CYTOMETRY: A SCALABLE METHOD FOR DIRECTED COMBINATORIAL SYNTHESIS
(2007) Doctor Philosophy — Principal Advisor
Other advisors:
DEVELOPMENT OF MULTIPLEXED PARTICLE ASSAYS FOR DNA SCREENING APPLICATIONS
(2006) Doctor Philosophy — Principal Advisor
Other advisors:
PREPARATION OF NOVEL MATERIALS FOR RAPID DNA SEQUENCING
(2006) Doctor Philosophy — Principal Advisor
Other advisors:
NANOSTRUCTURED BIOMATERIALS AND DEVICES
(2003) Doctor Philosophy — Principal Advisor
Other advisors:
Nanoshearing: A Microfluidic Approach for Isolation and Enumeration of Cancer Biomarkers
(2015) Doctor Philosophy — Joint Principal Advisor
Development of point-of-care and multiplex diagnostic methods for the detection of plant pathogens
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
Detection and quantification of miRNA promoter DNA methylation as prognostic biomarkers for breast cancer
(2012) Doctor Philosophy — Associate Advisor
Other advisors:
(2010) Doctor Philosophy — Associate Advisor
Other advisors:
Self Assembled Nano-coats for Protection of Foreign Tissue Transplants
(2008) Doctor Philosophy — Associate Advisor
Other advisors:
IN VITRO AND IN VIVO CHARACTERIZATION OF CELLULAR RESPONSES TO PHBV AND HYDROXYAPATITE/PHBV COMPOSITES AS BONE BIOMATERIALS
(2007) Doctor Philosophy — Associate Advisor
Other advisors: