The University of Queensland

Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study

Nikles, Catherine J., McKinlay, Lynne, Mitchell, Geoffrey K., Carmont, Sue-Ann S., Senior, Hugh E., Waugh, Mary-Clare A., Epps, Adrienne, Schluter, Philip J. and Lloyd, Owen T. (2014) Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study. Trials, 15 54: 1-11. doi:10.1186/1745-6215-15-54

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials

Nikles, Jane, Mitchell, Geoffrey K., Hardy, Janet, Agar, Meera, Senior, Hugh, Carmont, Sue-Ann, Schluter, Philip J., Good, Phillip, Vora, Rohan and Currow, David (2013) Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials. BMC Palliative Care, 12 39: 1-15. doi:10.1186/1472-684X-12-39

Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials

Senior, Hugh E. J., McKinlay, Lynne, Nikles, Jane, Schluter, Philip J., Carmont, Sue-Ann, Waugh, Mary-Clare, Epps, Adrienne, Lloyd, Owen and Mitchell, Geoffrey K. (2013) Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials. BMC Pediatrics, 13 1: 89.1-89.7. doi:10.1186/1471-2431-13-89

Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol

Senior, Hugh E. J., Mitchell, Geoffrey K., Nikles, Jane, Carmont, Sue-Ann, Schluter, Philip J., Currow, David C., Vora, Rohan, Yelland, Michael J., Agar, Meera, Good, Phillip D. and Hardy, Janet R. (2013) Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol. BMC Palliative Care, 12 1: 17.1-17.6. doi:10.1186/1472-684X-12-17

Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol)

Punja, Salima, Shamseer, Larissa, Hartling, Lisa, Urichuk, Liana, Vandermeer, Ben, Nikles, Catherine J. and Vohra, Sunita (2012) Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol). Cochrane Database of Systematic Reviews, 7: . doi:10.1002/14651858.CD009996

Impact of the SunSmart Early Childhood Program in Queensland

Harrison, Simone, Saunders, Vicki and Nikles, Jane (2012). Impact of the SunSmart Early Childhood Program in Queensland. In: Abstracts of the ACTM. Townsville Health Research Week, Townsville, QLD, Australia, (38-38). 8 - 12 October 2012.

Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care

Nikles, Jane, Mitchell, Geoffrey K., Schluter, Philip, Good, Phillip, Hardy, Janet, Rowett, Debra, Shelby-James, Tania, Vohra, Sunita and Currow, David (2011) Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care. Journal of Clinical Epidemiology, 64 5: 471-480. doi:10.1016/j.jclinepi.2010.05.009

Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer

Hardy, Janet Rea, Carmont, Sue-Ann S., O'Shea, Angela, Vora, Rohan, Schluter, Philip, Nikles, Catherine Jane and Mitchell, Geoffrey Keith (2010) Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer. Journal of Palliative Medicine, 13 10: 1193-1197. doi:10.1089/jpm.2010.0185

Using N-of-1 Trials to improve patient management and save costs

Scuffham, Paul A., Nikles, Jane, Mitchell, Geoffrey K., Yelland, Michael J., Vine, Norma, Poulos, Christopher J., Pillans, Peter I., Bashford, Guy, del Mar, Chris, Schluter, Philip J. and Glasziou, Paul (2010) Using N-of-1 Trials to improve patient management and save costs. Journal of General Internal Medicine, 25 9: 906-913. doi:10.1007/s11606-010-1352-7

Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use

Nikles, Jane, Mitchell, Geoffrey K., Clavarino, Alexandra, Yelland, Michael J. and Del Mar, Christopher B. (2010) Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use. Australian Health Review, 34 1: 131-136. doi:10.1071/AH09654

Prioritising drugs for single patient (n-of-1) trials in palliative care

Nikles, J., Mitchell, G., Walters, J., Hardy, J., Good, P., Rowett, D., Shelby-James, T. and Currow, D. (2009) Prioritising drugs for single patient (n-of-1) trials in palliative care. Palliative Medicine, 23 7: 623-634. doi:10.1177/0269216309106461

N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain

Yelland, Michael J., Poulos, Christopher J., Pillans, Peter I., Bashford, Guy M., Nikles, Catherine Jane, Sturtevant, Joanna M., Vine, Norma, Del Mar, Christopher, Schluter, Philip J., Tan, Meng, Chan, Jonathon, Mackenzie, Fraser and Brown, Robyn (2009) N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain. Pain Medicine, 10 4: 754-761. doi:10.1111/j.1526-4637.2009.00615.x

Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience

Scuffham, P. A., Yelland, M. J., Nikles, C. J., Pietrzak, E. and Wilkinson, D. (2008) Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience. Value in Health, 11 1: 97-109. doi:10.1111/j.1524-4733.2007.00218.x

Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder

Nikles, C. Jane, Mitchell, Geoffrey K., Del Mar, Chris B., McNairn, Norma and Clavarino, Alexandra (2007) Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder. European Journal of Clinical Pharmacology, 63 11: 985-989. doi:10.1007/s00228-007-0361-x

Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials

Yelland, M. J., Nikles, C. J., McNairn, N., Del Mar, C. B., Schluter, P. J. and Brown, R. M. (2007) Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials. Rheumatology, 46 1: 135-140. doi:10.1093/rheumatology/kel195

Using n-of-1 trials as a diagnostic clinical tool

Nikles, Jane (2006). Using n-of-1 trials as a diagnostic clinical tool PhD Thesis, Population Health, The University of Queensland.

An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder

Nikles, C. J., Mitchell, G. K., Del Mar, C. B., Clavarino, A. and McNairn, N. (2006) An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder. Pediatrics, 117 6: 2040-2046. doi:10.1542/peds.2005-1328

Using n-of-1 trials as a clinical tool to improve prescribing

Nikles, C. J., Clavarino, A. M. and Del Mar, C. B. (2005) Using n-of-1 trials as a clinical tool to improve prescribing. British Journal Of General Practice, 55 512: 175-180.

The role of paracetamol in chronic pain: An evidence-based approach

Nikles, C. J., Yelland, M., Del Mar, C. and Wilkinson, D. (2005) The role of paracetamol in chronic pain: An evidence-based approach. American Journal of Therapeutics, 12 1: 80-91. doi:10.1097/00045391-200501000-00011

Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials

Coxeter, P. D., Schluter, P. J., Eastwood, H. L., Nikles, C. J. and Glasziou, P. P. (2003) Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials. Complementary Therapies In Medicine, 11 4: 215-222. doi:10.1016/S0965-2299(03)00122-5

Bias Influencing Maternal Reports of Child Behaviour and Emotional State

Najman, J. M., Williams, G. M., Nikles, J., Spence, S., Bor, W., O'Callaghan, M., Le Brocque, R., Andersen, M. J. and Shuttlewood, G. J. (2001) Bias Influencing Maternal Reports of Child Behaviour and Emotional State. Social Psychiatry and Psychiatric Epidemiology, 36 4: 186-194. doi:10.1007/s001270170062

Preliminary experiences with a single-patient trials service in general practice

Nikles, C. J., Glasziou, P. P., Del Mar, C. B., Duggan, C. M., Clavarino, A. M. and Yelland, M. J. (2000) Preliminary experiences with a single-patient trials service in general practice. Medical Journal of Australia, 173 2: 100-103.

Mothers' mental illness and child behavior problems: Cause-effect association or observation bias

Najman, J. M., Williams, G. M., Nikles, J., Spence, S. H., Bor, W., O'Callaghan, M., Le Brocque, R. M. and Andersen, M.J. (2000) Mothers' mental illness and child behavior problems: Cause-effect association or observation bias. Journal of The American Academy of Child And Adolescent Psychiatry, 39 5: 592-602. doi:10.1097/00004583-200005000-00013

Managing ADHD in general practice. N of 1 trials can help!

Duggan, C. M., Mitchell, G. K., Nikles, C. J., Glasziou, P. P., Del Mar, C. B. and Clavarino, A. M. (2000) Managing ADHD in general practice. N of 1 trials can help!. Australian Family Physician, 29 12: 1205-1209.

Managing ADHD in general practice: N of 1 trials can help

Duggan, C., Mitchell, G., Nikles, J., Glasziou, P. and Del Mar, C. (2000) Managing ADHD in general practice: N of 1 trials can help. Australian Family Physician, 29 1205-1209.

N of 1 trials: practical tools for medication management

Nikles, C. J., Glasziou, P. P., Del Mar, C. B., Duggan, C. and Mitchell, G. K. (2000) N of 1 trials: practical tools for medication management. Australian Family Physician, 29 11: 1108-1112.

Using single patient trials to determine the effectiveness of psychostimulants in fatigue in advanced cancer patients

Mitchell, Geoffrey, Hardy, Janet, Vora, Rohan, Currow, David, Schluter, Philip, Nikles, Jane and Yelland, Michael (2008) Using single patient trials to determine the effectiveness of psychostimulants in fatigue in advanced cancer patients :

Introduction

Nikles, Jane and Mitchell, Geoffrey (2015). Introduction. In Jane Nikles and Geoffrey Mitchell (Ed.), The essential guide to N-of-1 trials in health (pp. 1-8) Dordrecht, The Netherlands: Springer. doi:10.1007/978-94-017-7200-6_1

What are N-of-1 Trials?

Nikles, Jane (2015). What are N-of-1 Trials?. In Jane Nikles and Geoffrey Mitchell (Ed.), The essential guide to N-of-1 trials in health (pp. 9-17) Dordecht, Netherlands: Springer. doi:10.1007/978-94-017-7200-6_2

Where Are N-of-1 Trials Headed?

Nikles, Jane (2015). Where Are N-of-1 Trials Headed?. In Jane Nikles and Geoffrey Mitchell (Ed.), The essential guide to N-of-1 trials in health (pp. 233-241) Dordrecht, The Netherlands: Springer. doi:10.1007/978-94-017-7200-6_17

Individualised medication effectiveness tests as a means of targeting stimulants to responders in attention deficit hyperactivity disorder

Nikles, C. J., Mitchell, G. K., Del Mar, C. B. and Clavarino, A. (2005). Individualised medication effectiveness tests as a means of targeting stimulants to responders in attention deficit hyperactivity disorder. In M. P. Larimer (Ed.), Attention Deficit Hyperactivity Disorder Research Developments 1 ed. (pp. 169-187) New York, U.S.A.: Nova Science.

A retrospective descriptive observational study of patients who presented to an Australian hospital Emergency Department with neck soft tissue injury

Nikles, Jane, Khan, Subaat, Leou, John, Keijzers, Gerben, Ng, Joanna, Bond, Catherine, Nakamura, Gota, Le, Rhonda and Sterling, Michele (2019) A retrospective descriptive observational study of patients who presented to an Australian hospital Emergency Department with neck soft tissue injury. Emergency Medicine Australiasia, . doi:10.1111/1742-6723.13253

Use of and attitudes to the role of medication for acute whiplash injury: a preliminary survey of emergency department doctors: emergency department Whiplash Medication Survey

Nikles, Jane, Keijzers, Gerben, De Silva, Muthuwahandi Ishan Diluka, Khan, Subaat and Sterling, Michele (2018) Use of and attitudes to the role of medication for acute whiplash injury: a preliminary survey of emergency department doctors: emergency department Whiplash Medication Survey. Emergency Medicine Australasia, . doi:10.1111/1742-6723.13190

Views and perceptions about locally manufactured medicines in Ethiopia: a qualitative study of physicians, patients and regulatory authorities

Alemayehu, Chalachew, Mitchell, Geoff, Nikles, Jane, Aseffa, Abraham and Clavarino, Alexandra (2018) Views and perceptions about locally manufactured medicines in Ethiopia: a qualitative study of physicians, patients and regulatory authorities. BMC Health Services Research, 18 1: 624. doi:10.1186/s12913-018-3410-5

N-of-1 trials in the clinical care of patients in developing countries: a systematic review

Alemayehu, Chalachew, Nikles, Jane and Mitchell, Geoffrey (2018) N-of-1 trials in the clinical care of patients in developing countries: a systematic review. Trials, 19 1: 246. doi:10.1186/s13063-018-2596-5

Herbal medicines used in the treatment of chronic insomnia and how they influence sleep patterns: a review

Harris, Thomas and Nikles, Jane (2018) Herbal medicines used in the treatment of chronic insomnia and how they influence sleep patterns: a review. Journal of Complementary Medicine and Alternative Healthcare, 6 1: . doi:10.19080/JCMAH.2018.06.555680

Barriers for conducting clinical trials in developing countries- A systematic review

Alemayehu, Chalachew, Mitchell, Geoffrey and Nikles, Jane (2018) Barriers for conducting clinical trials in developing countries- A systematic review. International Journal for Equity in Health, 17 1: 37. doi:10.1186/s12939-018-0748-6

Pregabalin versus placebo in targeting pro-nociceptive mechanisms to prevent chronic pain after whiplash injury in at-risk individuals - a feasibility study for a randomised controlled trial

Nikles, J., Keijzers, G., Mitchell, G., Schug, S., Ware, R., McLean, S. A., Connelly, L., Gibson, S., Farrell, S. F. and Sterling, M. (2018) Pregabalin versus placebo in targeting pro-nociceptive mechanisms to prevent chronic pain after whiplash injury in at-risk individuals - a feasibility study for a randomised controlled trial. Trials, 19 1: 1-11. doi:10.1186/s13063-018-2450-9

Management of Whiplash Associated Disorders in Australian general practice

Nikles, Jane, Yelland, Michael, Bayram, Clare, Miller, Graeme and Sterling, Michele (2017) Management of Whiplash Associated Disorders in Australian general practice. Bmc Musculoskeletal Disorders, 18 1-9. doi:10.1186/s12891-017-1899-0

Sun protective behaviors at an outdoor entertainment event in Australia

Barrett, Fiona, Usher, Kim, Woods, Cindy, Harrison, Simone L, Nikles, Jane and Conway, Jane (2017) Sun protective behaviors at an outdoor entertainment event in Australia. Nursing and Health Sciences, 20 1: 132-138. doi:10.1111/nhs.12396

A series of N-of-1 trials to assess therapeutic interchangeability of two Enalapril formulations in the treatment of hypertension, Addis Ababa, Ethiopia

Alemayu, Chalachew, Mitchell, Geoffrey, Aseffa, Abraham, Clavarino, Alexandra, McGree, James and Nikles, Jane (2017) A series of N-of-1 trials to assess therapeutic interchangeability of two Enalapril formulations in the treatment of hypertension, Addis Ababa, Ethiopia. Trials, 18 1: 470. doi:10.1186/s13063-017-2212-0

A series of n-of-1 trials of stimulants in brain injured children

Nikles, Jane, Mitchell, Geoffrey, McKinlay, Lynne, Waugh, Mary-Clare, Epps, Adrienne, Carmont, Sue-Ann, Schluter, Philip J., Lloyd, Owen and Senior, Hugh (2017) A series of n-of-1 trials of stimulants in brain injured children. NeuroRehabilitation, 40 1: 11-21. doi:10.3233/NRE-161386

The single-case reporting guideline in behavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2017) The single-case reporting guideline in behavioural interventions (SCRIBE) 2016 statement. Neuropsychological Rehabilitation, 27 1: 1-15. doi:10.1080/09602011.2016.1190533

The single-case reporting guideline in BEhavioural Interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The single-case reporting guideline in BEhavioural Interventions (SCRIBE) 2016 statement. Remedial and Special Education, 37 6: 370-380. doi:10.1177/0741932516652893

Melatonin in youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial

Punja, Salima, Nikles, Catherine J., Senior, Hugh, Mitchell, Geoffrey, Schmid, Christopher H., Heussler, Helen, Witmans, Manisha and Vohra, Sunita (2016) Melatonin in youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial. Trials, 17 1: 375. doi:10.1186/s13063-016-1499-6

The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement. Aphasiology, 30 7: 862-876. doi:10.1080/02687038.2016.1178022

Do N-of-1 trials need IRB review?

Cen, Ruiqi, Hussain, Azad, Pak, Kirk J., Mitchell, Geoffrey, Nikles, Jane, Gaudreau, Stephanie, Bazzano, Lydia A. and Breault, Joseph L. (2016) Do N-of-1 trials need IRB review?. Journal of Empirical Research on Human Research Ethics, 11 3: 250-255. doi:10.1177/1556264616662560

The single-case reporting guideline in BEhavioural interventions (SCRIBE) 2016 Statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The single-case reporting guideline in BEhavioural interventions (SCRIBE) 2016 Statement. Physical Therapy, 96 7: e1-e10. doi:10.2522/ptj.2016.96.7.e1

The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement. Evidence-Based Communication Assessment and Intervention, 10 1: 44-58. doi:10.1080/17489539.2016.1190525

Sun protection policies of Australian primary schools in a region of high sun exposure

Harrison, S. L., Garzon-Chavez, D. R. and Nikles, C. J. (2016) Sun protection policies of Australian primary schools in a region of high sun exposure. Health Education Research, 31 3: 416-428. doi:10.1093/her/cyw020

The Single-Case Reporting Guideline in BEhavioural Interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The Single-Case Reporting Guideline in BEhavioural Interventions (SCRIBE) 2016 statement. Canadian Journal of Occupational Therapy, 83 3: 184-195. doi:10.1177/0008417416648124

The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement. Journal of School Psychology, 56 133-142. doi:10.1016/j.jsp.2016.04.001

The Single-Case Reporting Guideline in BEhavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016) The Single-Case Reporting Guideline in BEhavioural interventions (SCRIBE) 2016 statement. Journal of Clinical Epidemiology, 73 142-152. doi:10.1016/j.jclinepi.2016.04.006

N-of-1 trials can be aggregated to generate group mean treatment effects: a systematic review and meta-analysis

Punja, Salima, Xu, Dongying, Schmid, Christopher H., Hartling, Lisa, Urichuk, Liana, Nikles, Catherine Jane and Vohra, Sunita (2016) N-of-1 trials can be aggregated to generate group mean treatment effects: a systematic review and meta-analysis. Journal of Clinical Epidemiology, 76 65-75. doi:10.1016/j.jclinepi.2016.03.026

Single patient multiple cross-over studies to determine the effectiveness of paracetamol in relieving pain suffered by patients with advanced cancer taking regular opioids: a pilot study.

Nikles, Jane, Mitchell, Geoffrey K., Hardy, Janet, Senior, Hugh, Carmont, Sue-Ann, Schluter, Philip J., Vora, Rohan, Currow, David and Yelland, Michael (2016) Single patient multiple cross-over studies to determine the effectiveness of paracetamol in relieving pain suffered by patients with advanced cancer taking regular opioids: a pilot study.. Palliative Medicine: a multiprofessional journal, 30 8: 1-3. doi:10.1177/0269216316635012

Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents (Review)

Punja, Salima, Shamseer, Larissa, Hartling, Lisa, Urichuk, Liana, Vandermeer, Ben, Nikles, Jane and Vohra, Sunita (2016) Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents (Review). Cochrane Database of Systematic Reviews, 2016 2: . doi:10.1002/14651858.CD009996.pub2

To meta-analyze or not to meta-analyze? A combined meta-analysis of N-of-1 trial data with RCT data on amphetamines and methylphenidate for pediatric ADHD

Punja, Salima, Schmid, Christopher H., Hartling, Lisa, Urichuk, Liana, Nikles, Catherine Jane and Vohra, Sunita (2016) To meta-analyze or not to meta-analyze? A combined meta-analysis of N-of-1 trial data with RCT data on amphetamines and methylphenidate for pediatric ADHD. Journal of Clinical Epidemiology, 76 76-81. doi:10.1016/j.jclinepi.2016.03.021

The effect of methylphenidate on fatigue in advanced cancer: an aggregated n-of-1 trial

Mitchell, Geoffrey K., Hardy, Janet R., Nikles, Catherine J., Carmont, Sue-Ann S., Senior, Hugh E., Schluter, Philip J., Good, Philip and Currow, David C. (2015) The effect of methylphenidate on fatigue in advanced cancer: an aggregated n-of-1 trial. Journal of Pain and Symptom Management, 50 3: 289-296. doi:10.1016/j.jpainsymman.2015.03.009

CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement

Vohra, Sunita, Shamseer, Larissa, Sampson, Margaret, Bukutu, Cecilia, Schmid, Christopher H., Tate, Robyn, Nikles, Jane, Zucker, Deborah R., Kravitz, Richard, Guyatt, Gordon, Altman, Douglas G., Moher, David and the CENT group (2015) CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement. Journal of Clinical Epidemiology, 76 9-17. doi:10.1016/j.jclinepi.2015.05.004

CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration

Shamseer, Larissa, Sampson, Margaret, Bukutu, Cecilia, Schmid, Christopher H., Nikles, Jane, Tate, Robyn, Johnston, Bradley C., Zucker, Deborah, Shadish, William R., Kravitz, Richard, Guyatt, Gordon, Altman, Douglas G., Moher, David, Vohra, Sunita and the CENT group (2015) CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration. Journal of Clinical Epidemiology, 76 18-46. doi:10.1016/j.jclinepi.2015.05.018

Testing pilocarpine drops for dry mouth in advanced cancer using n-of-1 trials: A feasibility study

Nikles, Jane, Mitchell, Geoffrey K., Hardy, Janet, Agar, Meera, Senior, Hugh Edgar John, Carmont, Sue-Ann, Schluter, Philip J., Good, Phillip, Vora, Rohan and Currow, David (2015) Testing pilocarpine drops for dry mouth in advanced cancer using n-of-1 trials: A feasibility study. Palliative Medicine, 29 10: 967-974. doi:10.1177/0269216315585473

CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement

Vohra, Sunita, Shamseer, Larissa, Sampson, Margaret, Bukutu, Cecilia, Schmid, Christopher H., Tate, Robyn, Nikles, Jane, Zucker, Deborah R., Kravitz, Richard, Guyatt, Gordon, Altman, Douglas G., Moher, David and the CENT group (2015) CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement. BMJ, 350 . doi:10.1136/bmj.h1738

CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration

Shamseer, Larissa, Sampson, Margaret, Bukutu, Cecilia, Schmid, Christopher H., Nikles, Jane, Tate, Robyn, Johnston, Bradley C., Zucker, Deborah, Shadish, William R., Kravitz, Richard, Guyatt, Gordon, Altman, Douglas G., Moher, David, Vohra, Sunita and the CENT group (2015) CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration. BMJ, 350 . doi:10.1136/bmj.h1793

Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study

Nikles, Catherine J., McKinlay, Lynne, Mitchell, Geoffrey K., Carmont, Sue-Ann S., Senior, Hugh E., Waugh, Mary-Clare A., Epps, Adrienne, Schluter, Philip J. and Lloyd, Owen T. (2014) Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study. Trials, 15 54: 1-11. doi:10.1186/1745-6215-15-54

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials

Nikles, Jane, Mitchell, Geoffrey K., Hardy, Janet, Agar, Meera, Senior, Hugh, Carmont, Sue-Ann, Schluter, Philip J., Good, Phillip, Vora, Rohan and Currow, David (2013) Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials. BMC Palliative Care, 12 39: 1-15. doi:10.1186/1472-684X-12-39

Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials

Senior, Hugh E. J., McKinlay, Lynne, Nikles, Jane, Schluter, Philip J., Carmont, Sue-Ann, Waugh, Mary-Clare, Epps, Adrienne, Lloyd, Owen and Mitchell, Geoffrey K. (2013) Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials. BMC Pediatrics, 13 1: 89.1-89.7. doi:10.1186/1471-2431-13-89

An observational study of sun-protective behaviour at an outdoor spectator sporting event in a region of high sun exposure

Nikles, Jane and Harrison, Simone Lee (2013) An observational study of sun-protective behaviour at an outdoor spectator sporting event in a region of high sun exposure. Journal of Carcinogenesis and Mutagenesis, . doi:10.4172/2157-2518.S4-003

Don’t burn the baby: advice from Australian nurses recommending therapeutic sun exposure during infancy

Harrison, Simone Lee, Nikles, Jane and Nowak, Madeleine (2013) Don’t burn the baby: advice from Australian nurses recommending therapeutic sun exposure during infancy. Open Journal of Preventive Medicine, 3 2: 212-218. doi:10.4236/ojpm.2013.32029

Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol

Senior, Hugh E. J., Mitchell, Geoffrey K., Nikles, Jane, Carmont, Sue-Ann, Schluter, Philip J., Currow, David C., Vora, Rohan, Yelland, Michael J., Agar, Meera, Good, Phillip D. and Hardy, Janet R. (2013) Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol. BMC Palliative Care, 12 1: 17.1-17.6. doi:10.1186/1472-684X-12-17

Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol)

Punja, Salima, Shamseer, Larissa, Hartling, Lisa, Urichuk, Liana, Vandermeer, Ben, Nikles, Catherine J. and Vohra, Sunita (2012) Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol). Cochrane Database of Systematic Reviews, 7: . doi:10.1002/14651858.CD009996

Exploring melatonin prescribing among customers of compounding pharmacies in Australia

Nikles, Jane, Lo, Victor, Giam, Jennifer A . and Saini, Bandana (2012) Exploring melatonin prescribing among customers of compounding pharmacies in Australia. Medical Journal of Australia, 196 6: 384-385. doi:10.5694/mja12.10145

Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care

Nikles, Jane, Mitchell, Geoffrey K., Schluter, Philip, Good, Phillip, Hardy, Janet, Rowett, Debra, Shelby-James, Tania, Vohra, Sunita and Currow, David (2011) Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care. Journal of Clinical Epidemiology, 64 5: 471-480. doi:10.1016/j.jclinepi.2010.05.009

Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer

Hardy, Janet Rea, Carmont, Sue-Ann S., O'Shea, Angela, Vora, Rohan, Schluter, Philip, Nikles, Catherine Jane and Mitchell, Geoffrey Keith (2010) Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer. Journal of Palliative Medicine, 13 10: 1193-1197. doi:10.1089/jpm.2010.0185

Using N-of-1 Trials to improve patient management and save costs

Scuffham, Paul A., Nikles, Jane, Mitchell, Geoffrey K., Yelland, Michael J., Vine, Norma, Poulos, Christopher J., Pillans, Peter I., Bashford, Guy, del Mar, Chris, Schluter, Philip J. and Glasziou, Paul (2010) Using N-of-1 Trials to improve patient management and save costs. Journal of General Internal Medicine, 25 9: 906-913. doi:10.1007/s11606-010-1352-7

Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use

Nikles, Jane, Mitchell, Geoffrey K., Clavarino, Alexandra, Yelland, Michael J. and Del Mar, Christopher B. (2010) Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use. Australian Health Review, 34 1: 131-136. doi:10.1071/AH09654

Prioritising drugs for single patient (n-of-1) trials in palliative care

Nikles, J., Mitchell, G., Walters, J., Hardy, J., Good, P., Rowett, D., Shelby-James, T. and Currow, D. (2009) Prioritising drugs for single patient (n-of-1) trials in palliative care. Palliative Medicine, 23 7: 623-634. doi:10.1177/0269216309106461

N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain

Yelland, Michael J., Poulos, Christopher J., Pillans, Peter I., Bashford, Guy M., Nikles, Catherine Jane, Sturtevant, Joanna M., Vine, Norma, Del Mar, Christopher, Schluter, Philip J., Tan, Meng, Chan, Jonathon, Mackenzie, Fraser and Brown, Robyn (2009) N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain. Pain Medicine, 10 4: 754-761. doi:10.1111/j.1526-4637.2009.00615.x

Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience

Scuffham, P. A., Yelland, M. J., Nikles, C. J., Pietrzak, E. and Wilkinson, D. (2008) Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience. Value in Health, 11 1: 97-109. doi:10.1111/j.1524-4733.2007.00218.x

Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder

Nikles, C. Jane, Mitchell, Geoffrey K., Del Mar, Chris B., McNairn, Norma and Clavarino, Alexandra (2007) Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder. European Journal of Clinical Pharmacology, 63 11: 985-989. doi:10.1007/s00228-007-0361-x

Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials

Yelland, M. J., Nikles, C. J., McNairn, N., Del Mar, C. B., Schluter, P. J. and Brown, R. M. (2007) Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials. Rheumatology, 46 1: 135-140. doi:10.1093/rheumatology/kel195

An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder

Nikles, C. J., Mitchell, G. K., Del Mar, C. B., Clavarino, A. and McNairn, N. (2006) An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder. Pediatrics, 117 6: 2040-2046. doi:10.1542/peds.2005-1328

Using n-of-1 trials as a clinical tool to improve prescribing

Nikles, C. J., Clavarino, A. M. and Del Mar, C. B. (2005) Using n-of-1 trials as a clinical tool to improve prescribing. British Journal Of General Practice, 55 512: 175-180.

Do individualized medication effectiveness tests (N-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?

Nikles, C. J., Yelland, M., Glasziou, P. P. and Del Mar, C (2005) Do individualized medication effectiveness tests (N-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?. American Journal of Therapeutics, 12 1: 92-97. doi:10.1097/00045391-200501000-00012

The role of paracetamol in chronic pain: An evidence-based approach

Nikles, C. J., Yelland, M., Del Mar, C. and Wilkinson, D. (2005) The role of paracetamol in chronic pain: An evidence-based approach. American Journal of Therapeutics, 12 1: 80-91. doi:10.1097/00045391-200501000-00011

Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials

Coxeter, P. D., Schluter, P. J., Eastwood, H. L., Nikles, C. J. and Glasziou, P. P. (2003) Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials. Complementary Therapies In Medicine, 11 4: 215-222. doi:10.1016/S0965-2299(03)00122-5

Bias Influencing Maternal Reports of Child Behaviour and Emotional State

Najman, J. M., Williams, G. M., Nikles, J., Spence, S., Bor, W., O'Callaghan, M., Le Brocque, R., Andersen, M. J. and Shuttlewood, G. J. (2001) Bias Influencing Maternal Reports of Child Behaviour and Emotional State. Social Psychiatry and Psychiatric Epidemiology, 36 4: 186-194. doi:10.1007/s001270170062

Preliminary experiences with a single-patient trials service in general practice

Nikles, C. J., Glasziou, P. P., Del Mar, C. B., Duggan, C. M., Clavarino, A. M. and Yelland, M. J. (2000) Preliminary experiences with a single-patient trials service in general practice. Medical Journal of Australia, 173 2: 100-103.

Mothers' mental illness and child behavior problems: Cause-effect association or observation bias

Najman, J. M., Williams, G. M., Nikles, J., Spence, S. H., Bor, W., O'Callaghan, M., Le Brocque, R. M. and Andersen, M.J. (2000) Mothers' mental illness and child behavior problems: Cause-effect association or observation bias. Journal of The American Academy of Child And Adolescent Psychiatry, 39 5: 592-602. doi:10.1097/00004583-200005000-00013

Managing ADHD in general practice. N of 1 trials can help!

Duggan, C. M., Mitchell, G. K., Nikles, C. J., Glasziou, P. P., Del Mar, C. B. and Clavarino, A. M. (2000) Managing ADHD in general practice. N of 1 trials can help!. Australian Family Physician, 29 12: 1205-1209.

Managing ADHD in general practice: N of 1 trials can help

Duggan, C., Mitchell, G., Nikles, J., Glasziou, P. and Del Mar, C. (2000) Managing ADHD in general practice: N of 1 trials can help. Australian Family Physician, 29 1205-1209.

N of 1 trials: practical tools for medication management

Nikles, C. J., Glasziou, P. P., Del Mar, C. B., Duggan, C. and Mitchell, G. K. (2000) N of 1 trials: practical tools for medication management. Australian Family Physician, 29 11: 1108-1112.

Infections in renal transplant recipients

Hardie, I. R., Moses, D. and Nikles, J. (1984) Infections in renal transplant recipients. Transplantation Proceedings, 16 4: 988-989.

N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension, Ethiopia

Alemayhu, Chalachew , Mitchell, Geoffrey , Nikles, Jane , Aseffa, Abraham , Clavarino, Alexandra and McGree, James (2017). N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension, Ethiopia. In: PCRIS, Brisbane, Australia, (). 7-9 August 2017.

Sun protection provided by regulation school uniforms worn by primary school students in Queensland during summer

Bates, N., Emeto, T., Turner, D., Nikles, J. and Harrison, S. (2016). Sun protection provided by regulation school uniforms worn by primary school students in Queensland during summer. In: Abstracts from the Townsville Health Research Week 2016. Townsville Health Research Week 2016: Spotlight on Preventative Health, Townsville, QLD, Australia, (25-25). 12-15 September 2016.

The single-case reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The single-case reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement. In: 2016 Annual Conference & Expo! 2016 Annual Conference and Expo. AOTA 96th Annual Conference and Expo, Chicag, Il, United States, (1-11). 7-10 April 2016. doi:10.5014/ajot.2016.704002

Randomised double blind placebo controlled phase II trial of melatonin for prevention of delirium in inpatients with advanced cancer

Agar, M., Lawlor, P., Caplan, G., Ely, E. W., Lam, L., de Souza, P. and Nikles, J. (2015). Randomised double blind placebo controlled phase II trial of melatonin for prevention of delirium in inpatients with advanced cancer. In: Australian Palliative Care Conference, Melbourne, VIC, Australia, (). 1-4 September 2015.

Using individualized randomized trials to improve health outcomes and reduce costs

Mitchell, G., Nikles, J., Senior, H., Whitty, J., McGree, James, Carmont, S., Kravitz, R., Bazzano, L. and Schmid, C. (2015). Using individualized randomized trials to improve health outcomes and reduce costs. In: US-Australia Biomedical Research Partnership Conference, Canberra, ACT, Australia, (28-28). 13 July 2015.

Overview of N-of-1 study suite – lessons learned from three aggregated N-of-1 trials

Mitchell, Geoff, Nikles, Jane, Carmont, Sue-Ann, Hardy, Janet, Good, Phillip, Agar, Meera, Clark, Katherine, Douglas, Carol, Vora, Rohan, Currow, David and Senior, H. (2013). Overview of N-of-1 study suite – lessons learned from three aggregated N-of-1 trials. In: PaCCSC 4th Annual Scientific Meeting and Research Forum 2013, Sydney, NSW, Australia, (28-28). 20-21 Mar, 2013.

Don't burn the baby: advice from Australian nurses recommending therapeutic sun exposure during infancy

Harrison, Simone and Nikles, Jane (2012). Don't burn the baby: advice from Australian nurses recommending therapeutic sun exposure during infancy. In: Abstracts of the ACTM. Townsville Health Research Week, Townsville, QLD, Australia, (30-30). 8 - 12 October 2012.

Impact of the SunSmart Early Childhood Program in Queensland

Harrison, Simone, Saunders, Vicki and Nikles, Jane (2012). Impact of the SunSmart Early Childhood Program in Queensland. In: Abstracts of the ACTM. Townsville Health Research Week, Townsville, QLD, Australia, (38-38). 8 - 12 October 2012.

Preliminary observations of hat wearing in Brisbane schools

Harrison, Simone and Nikles, Jane (2012). Preliminary observations of hat wearing in Brisbane schools. In: Abstracts of the ACTM. Townsville Health Research Week, Townsville, QLD, Australia, (38-38). 8 - 12 October 2012.

The effectiveness of methylphenidate in fatigue in advanced cancer: Aggregated n-of-1 trial results

Mitchell, G., Hardy, J., Carmont, S., Nikles, J., Senior, H., Schluter, P., Good, P., Agar, M., Clark, K., Vora, R. and Currow, D. (2012). The effectiveness of methylphenidate in fatigue in advanced cancer: Aggregated n-of-1 trial results. In: Australian and New Zealand Society of Palliative Medicine conference, Queenstown, New Zealand, (42-42). 4 - 7 September 2012.

The effectiveness of methylphenidate in fatigue in advanced cancer: aggregated N-of-1 trails

Mitchell, Geoffrey, Hardy, Janet, Carmont, Sue-Ann, Nikles, Jane, Senior, Hugh, Schluter, Philip, Good, Philip, Agar, Meera, Clark, Katherine, Vora,Rohan, Douglas, Carol and Currow, David (2012). The effectiveness of methylphenidate in fatigue in advanced cancer: aggregated N-of-1 trails. In: Ipswich Hospital Research Day, Ipswich, Qld, Australia, (). 1 September 2012.

Exploring melatonin use among customers of compounding pharmacies in Australia

Saini, B., Lo, V., Giam, J. and Nikles, J. (2011). Exploring melatonin use among customers of compounding pharmacies in Australia. In: Sleep and the city. Abstracts of Sleep DownUnder 2011, the 23rd Annual Scientific Meeting of the Australasian Sleep Association and Australasian Sleep Technologists Association. 23rd Annual Scientific Meeting of the Australasian Sleep Association and Australasian Sleep Technologists Association, Sydney, N.S.W., Australia, (38-38). 27-29 October 2011. doi:10.1111/j.1365-2869.2011.00953.x

The use of stimulant medication in children with brain injury

McKinlay, L., Lloyd, O., Nikles, J. and Mitchell, G. (2011). The use of stimulant medication in children with brain injury. In: Changed Lives, New pathways: A Conference on Children's Rehabilitation, Royal Children's Hospital, Herston QLD, Australia, (). 14 - 15 July 2011.

Investigating n-of-1 trials as a means of gathering palliative care evidence

Carmont, S., Currow, D., Hardy, J., Mitchell, G. K., Nikles, J., Schluter, P., Vora, R. and Yelland, M. (2008). Investigating n-of-1 trials as a means of gathering palliative care evidence. In: 8th Biennial Conference of the Australian and New Zealand Society of Palliative Medicine (ANZSPM), Darwin, NT, Australia, (). 23-26 September 2008.

Investigating the role of single patient trial as a means of gathering population level evidence in palliative care

Mitchell, G., Nikles, J., Hardy, J., Currow, D., Good, P., Rowett, D. and Walters, J. (2007). Investigating the role of single patient trial as a means of gathering population level evidence in palliative care. In: Prevention, Palliation and Cure: Progress through trials. Clinical Oncological Society of Australia 34th Annual Scientific Meeting, Adelaide, Australia, (A46-A46). 14-16 November, 2007. doi:10.1111/j.1743-7563.2007.00127.x

Could N-of-1 trials make prescribing more cost-effective?

Yelland, Michael, Pietrzak, Eva, Scuffham, Paul, Nikles, Jane and Wilkinson, David (2006). Could N-of-1 trials make prescribing more cost-effective?. In: 2006 General Practice and Primary Health Care Research Conference: Program & Abstracts. 2006 GP & PHC Research Conference: Optimising Impact, Perth, WA, Australia, (61-61). 5-7 July 2006.

Could N-of-1 trials make prescribing more cost-effective?

Yelland, Michael, Pietrzak, E,, Schluter, Philip, Nikles, Jane and Wilkinson, D. (2006). Could N-of-1 trials make prescribing more cost-effective?. In: RACGP 49th Annual Scientific Convention: Be the Future, Brisbane, QLD, Australia, (107-107). 5-8 October 2006.

Could n-of-1 trials make prescribing more cost effective?

Nikles, J., Pietrzak, E., Scuffham, P., Wilkinso, D. and Yelland, M. (2006). Could n-of-1 trials make prescribing more cost effective?. In: Convention Handbook. RACGP 49th Annual Scientific Convention: Be the Future, Brisbane, QLD, Australia, (107-107). 5-8 October 2006.

Do n-of-1 trials of celeocxib compared to sustained release paracetamol change patient use of drugs for osteoarthritis?

Yelland, Michael, Nikles, Jane, McNairn, Norma, Brown, Robyn, Del Mar, Christopher and Schluter, Philip (2006). Do n-of-1 trials of celeocxib compared to sustained release paracetamol change patient use of drugs for osteoarthritis?. In: RACGP 49th Annual Scientific Convention: Be the Future, Brisbane, QLD, Australia, (101-101). 5-8 October 2006.

Single patient trials of gabapentin - the experience from a pain clinic

Christopher Poulos, Guy Bashford, Michael Yelland, Jane Nikles, Norma McNairn and Nancy Fish (2006). Single patient trials of gabapentin - the experience from a pain clinic. In: Australian Faculty of Rehabilitation Medicine 14th Annual Scientific Meeting, Cairns, Australia, (). 2006.

Single patient trials of gabapentin for chronic neuropathic pain

Yelland, M. J., Nikles, J., McNairn, N. and Schluter, P. J. (2006). Single patient trials of gabapentin for chronic neuropathic pain. In: Australian Association of Musculoskeletal Medicine Annual Scientific Meeting, Canberra, Australia, (13-13). 21-24 September 2006.

Single patient trials comparing NSAIDs with paracetamol for osteoarthritis and chronic pain

Yelland, M., Nikles, J., McNairn, N., Glasziou, P. and Del Mar, C. (2005). Single patient trials comparing NSAIDs with paracetamol for osteoarthritis and chronic pain. In: Australian Association of Musculoskeletal Medicine Conference - Pain Management in the Elderly, Noosa, Australia, (). 3-7 March 2005.

Single patient trials comparing NSAIDs with paracetamol for osteoarthritis and chronic pain

Yelland, M., Nikles, J., McNairn, N., Glasziou, P. and Glasziou, C. (2005). Single patient trials comparing NSAIDs with paracetamol for osteoarthritis and chronic pain. In: Australian Association of Musculoskeletal Medicine Conference, Singapore, (). 2005.

Single patient trials of gabapentin for chronic neuropathic pain

Yelland, M. J., Nikles, C. J. and McNairn, N. (2005). Single patient trials of gabapentin for chronic neuropathic pain. In: Abstracts: 11th World Congress on Pain. 11th IASP World Congress on Pain, Sydney, NSW, Australia, (). 21-26 August 2005.

Do individualised medication effectiveness tests improve decisions about which drugs to use for osteoarthritis or chronic pain?

Nikles, C.J., Yelland, M., Glasziou, P., Del Mar, C., Pillans, P. and Sturtevant, J. (2004). Do individualised medication effectiveness tests improve decisions about which drugs to use for osteoarthritis or chronic pain?. In: 'Pain in the Modern Era'. 25th Annual Scientific Meeting of the Australian Pain Society, Canberra, Australia, (42-43). 7-10 March 2004.

Individual Medication Effectiveness Tests (IMETs) to assess the efficacy of gabapentin in individual patients with chronic neuropathic pain

Yelland, M., Nikles, J., Glasziou, P., Del Mar, C., Pillans, P. and Sturtevant, J. (2004). Individual Medication Effectiveness Tests (IMETs) to assess the efficacy of gabapentin in individual patients with chronic neuropathic pain. In: 25th Annual Scientific Meeting of the Australian Pain Society, Canberra, Australia, (). 7-10 March 2004.

Do individualised medication effectiveness tests improve decisions about which drugs to use for osteoarthritis or chronic pain?

Nikles, J., Yelland, M., Glasziou, P. and Del Mar, C. (2003). Do individualised medication effectiveness tests improve decisions about which drugs to use for osteoarthritis or chronic pain?. In: Queensland Health Research Conference, Brisbane, QLD, Australia, (). 2003.

Individual medication effectiveness tests (IMETs) to assess the efficacy of gabapentin in individual patients with chronic neuropathic pain

Yelland, M., Nikles, J., Glasziou, P., Del Mar, C., Pillans, P. and Sturtevant, J. (2003). Individual medication effectiveness tests (IMETs) to assess the efficacy of gabapentin in individual patients with chronic neuropathic pain. In: Queensland Health Research Conference, Brisbane, QLD, Australia, (). 2003.

N of 1 trials: individualizing the evidence

Mitchell, G., Del Mar, C., Glasziou, P. and Nikles, J. (2003). N of 1 trials: individualizing the evidence. In: The Australasian Pharmaceutical Science Association Annual Conference, Sydney, (49-49). 3-5 December 2003.

Achieving good compliance and followup in clinical trials

Yelland, M. J., Beller, E., Nikles, J. and Glasziou, P. (2002). Achieving good compliance and followup in clinical trials. In: 2002 General Practice Primary Health Care Research Conference: Research Making a difference to health and health care and Australian Association of Academic General Practice Research Meeting. Australian Association of Academic General Practice Research Meeting, Melbourne, VIC, Australia, (214-215). 29-31 May 2002.

Individual medication effectiveness tests of stimulants in the treatment of Attention Deficit Hyperactivity Disorder

Mitchell, G., Nikles, J., Glasziou, P., Del Mar, C. and Schluter, P. (2002). Individual medication effectiveness tests of stimulants in the treatment of Attention Deficit Hyperactivity Disorder. In: Quality Use of Medicines Conference, Canberra ACT, Australia, (). 2002.

Individual medication effectiveness tests of stimulants in the treatment of attention deficit hyperactivity disorder

Mitchell, G. K., Nikles, C.J., Glasziou, P. P., Del Mar, C. B. and Schluter, P. J. (2002). Individual medication effectiveness tests of stimulants in the treatment of attention deficit hyperactivity disorder. In: 2002 General Practice Primary Health Care Research Conference: Research - making a difference to health and health care. General Practice and Primary Health Care Conference, Melbourne, VIC, Australia, (165-166). 29-31 May 2002.

Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Yelland, M. and King, J. (2002). Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure. In: Quality Use of Medicines Conference, Canberra ACT, Australia, (). 2002.

Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Yelland, M. and King, J. (2002). Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure. In: General Practice and Primary Health Care conference, Melbourme, VIC, Australia, (). 29-31 May 2002.

Research as practice: using Individualised medication effectiveness tests to improve prescribing

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Mitchell, G., O'Connor, V., Price, J., Yelland, M., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A. and Schluter, P. (2002). Research as practice: using Individualised medication effectiveness tests to improve prescribing. In: General Practice and Primary Health Care conference, Melbourne VIC, Australia, (). 29-31 May 2002.

Research as practice: using individualised medication effectiveness tests to improve prescribing

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Mitchell, G., O'Connor, V., Price, J., Yelland, M., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A. and Schluter, P. (2002). Research as practice: using individualised medication effectiveness tests to improve prescribing. In: Quality Use of Medicines Conference, Canberra ACT, Australia, (). 2002.

Targeting stimulants to responders: Individual Medication Effectiveness Tests for Attention Deficit Hyperactivity Disorder

Mitchell, G. K., Nikles, C. J., Glasziou, P. P., Steer, P. and Jenkins-Manning, S. (2002). Targeting stimulants to responders: Individual Medication Effectiveness Tests for Attention Deficit Hyperactivity Disorder. In: Queensland Health & Medical Scientific Meeting: Smart Research, Smart Practice, Smart Outcomes. Queensland Health and Medical Scientific Meeting, Brisbane, Australia, (). 4-5 December, 2002.

Do psychological menopausal symptoms respond to HRT Individualised Medication Effectiveness Tests as an applied research tool

O'Connor, V. M., Askew, D. A., Spinks, A. B., Nikles, J.C.J., Duggan, C. M., Del Mar, C. B. and Glasziou, P. P. (2001). Do psychological menopausal symptoms respond to HRT Individualised Medication Effectiveness Tests as an applied research tool. In: Proceedings: General Practice & Primary Health Care Research Conference. General Practice & Primary Health Care Research Conference, Adelaide, Australia, (129-129). 31 May - 1 June 2001.

Do psychological menopausal symptoms respond to HRT? Individualised medication effectiveness tests as an applied research tool

O'Connor, V., Askew, D., Spinks, A., Nikles, J., Duggan, C., Del Mar, C. and Glasziou, P. (2001). Do psychological menopausal symptoms respond to HRT? Individualised medication effectiveness tests as an applied research tool. In: General Practice Evaluation Program Conference, Adelaide, South Australia, (). 2001.

Individualised Medication Effectiveness Tests to better manage ADHD

Mitchell, G. K., Duggan, C. M., Glasziou, P. P., Del Mar, C. B., Nikles, J.C.J., Janamian, T. and Schluter, P. J. (2001). Individualised Medication Effectiveness Tests to better manage ADHD. In: General Practice and Primary Health Care Research Conference - Proceedings. 2001 General Practice and Primary Health Care Research Conf, Canberra, (167-168). 31 May - 1 June 2001.

Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure

Nikles, J.C.J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B. and Yelland, M. J. (2001). Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure. In: Proceedings: General Practice & Primary Health Care Research Conference. General Practice & Primary Health Care Research Conference, Adelaide, South Australia, (141-141). 31 May - 1 June 2001.

Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure

Nikles, J., Duggan, C., Glasziou, P., Del Mar, C. and Yelland, M. (2001). Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure. In: General Practice Evaluation Program Conference, Adelaide, South Australia, (). 2001.

Individualised medication effectiveness tests of valerian for chronic insomnia

Nikles, J.C.J., Coxeter, P.D., Price, J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B. and Schluter, P. J. (2001). Individualised medication effectiveness tests of valerian for chronic insomnia. In: Proceedings: General Practice & Primary Health Care Research Conference. General Practice & Primary Health Care Research Conference, Adelaide, South Australia, (140-140). 31 May - 1 June 2001.

Individualised medication effectiveness tests of valerian for chronic insomnia

Nikles, J., Coxeter, P., Price, J., Duggan, C., Glasziou, P., Del Mar, C. and Schluter, P. (2001). Individualised medication effectiveness tests of valerian for chronic insomnia. In: General Practice Evaluation Program Conference, Adelaide, South Australia, (). 2001.

Individualised medication effectiveness tests to better manage ADHD

Mitchell, G., Duggan, C., Glasziou, P., Del Mar, C., Nikles, J., Janamian, T. and Schluter, P (2001). Individualised medication effectiveness tests to better manage ADHD. In: General Practice Evaluation Program Conference, Adelaide, South Australia, (). 2001.

Research as practice: using Individialised Medication Effectiveness tests to improve prescribing

Nikles, J.C.J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B., Coxeter, P.D., Askew, D. A., Janamian, T., Spinks, A. B., Clavarino, A. M., Mitchell, G. K., O'Connor, V. M., Price, J., Yelland, M. J. and Schluter, P. J. (2001). Research as practice: using Individialised Medication Effectiveness tests to improve prescribing. In: General Practice and Primary Health Care Research Conference - Proceedings. 2001 General Practice and Primary Health Care Research Conference & Australian Association of Academic General Practice Research Meeting 2001, Canberra, (143-144). 31 May - 1 June 2001.

Research as practice: using Individualised medication effectiveness tests to improve prescribing

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Mitchell, G., O'Connor, V., Price, J., Yelland, M., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A. and Schluter, P. (2001). Research as practice: using Individualised medication effectiveness tests to improve prescribing. In: General Practice and Primary Health Care conference, Brisbane, QLD, Australia, (). 2001.

Research as practice: using individualised medication effectiveness tests to improve prescribing

Nikles, J., Duggan, C., Glasziou, P., Del Mar, C., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A., Mitchell, G., O'Connor, V., Price, J., Yelland, M. and Schluter, P. (2001). Research as practice: using individualised medication effectiveness tests to improve prescribing. In: General Practice Evaluation Program Conference, Adelaide, South Australia, (). 2001.

Consumer perspectives of individualised medication effectiveness tests in General Practices

Nikles, J., Del Mar, C., Glasziou, P., Clavarino, A. and Duggan, C. (2000). Consumer perspectives of individualised medication effectiveness tests in General Practices. In: General Practice Evaluation Program Conference, Hobart , TAS, Australia, (). 2000.

Consumer perspectives of single patient trials in general practice

Clavarino, A. M., Del Mar, C. B., Duggan, C. M., Glasziou, P. P. and Nikles, C. J. (2000). Consumer perspectives of single patient trials in general practice. In: The 2000 General Practice Evaluation Program Conference Proceedings. The General Practice Evaluation Program, Hobart: Hotel Grand Chancellor, (210-211). 4-5 May 2000.

Individualised medication effectiveness tests of stimulants in Attention Deficit Hyperactivity Disorder

Mitchell G, Nikles, J., Glasziou, P. and Schluter P. (2000). Individualised medication effectiveness tests of stimulants in Attention Deficit Hyperactivity Disorder. In: General Practice Evaluation Program Conference, Hobart , TAS, Australia, (). 2000.

Individualised medication effectiveness tests service: feasibility in general practice

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Askew, D., Janamian, T. and Coxeter, P. (2000). Individualised medication effectiveness tests service: feasibility in general practice. In: RACGP 43rd Annual Scientific Convention, Townsville, QLD, Australia, (). 2000.

Is a individualised medication effectiveness tests service feasible in general practice? Preliminary experiences

Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Clavarino, A. and Yelland, M. (2000). Is a individualised medication effectiveness tests service feasible in general practice? Preliminary experiences. In: General Practice Evaluation Program Conference, Hobart , TAS, Australia, (). 2000.

Preliminary experience with single patient trials in general practice

Glasziou, P. P., Del Mar, C. B., Nikles, C. J. and Duggan, C. M. (2000). Preliminary experience with single patient trials in general practice. In: The 2000 General Practice Evaluation Program Conference Proceedings. The 2000 General Practice Evaluation Program, Hobart, (209-209). 2000.

Single patient trials in the treatment of ADHD in General Practice - a pilot study

Mitchell, G. K., Glasziou, P. P. and Nikles, C. J. (2000). Single patient trials in the treatment of ADHD in General Practice - a pilot study. In: WONCA 2000 Vienna Final Program. 6th European Conference on General Practice and Family Medicine, Vienna; Hafburg Conference Centre, Vienna, (136-137). 2-6 July 2000.

Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder

Mitchell, G. K., Nikles, C. J., Glasziou, P. P. and Schluter, P. J. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder. In: General Practice Evaluation Conference, Flinders University, Adelaide, Australia, (136-137). 2000.

Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study

Mitchell, G. K., Nikles, C. J., Glasziou, P. P. and Schluter, P. J. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study. In: 29th Annual Scientific Meeting Association of University Departments of General Practice, Bournemouth, England., (56-56). 2000.

Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study

Mitchell, G., Nikles, J., Glasziou, P. and Schluter, P. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study. In: 6th European WONCA Conference on General Practice & Family Doctors. 6th European Wonca Conference on General Practice & Family Doctors, Hafburg Conference Centre, Vienna, (143-143). 2 - 6 July 2000.

Single patient trials of stimulants in attention deficit hyperactivity disorder

Mitchell, G. K., Nikles, C. J., Glasziou, P. P. and Schluter, P. J. (2000). Single patient trials of stimulants in attention deficit hyperactivity disorder. In: The 2000 General Practice Evaluation Program Conference Proceedings. The General Practice Evaluation Program, Hobart, (203-203). 2000.

Individualised medication effectiveness tests in general practice

Nikles, J., Glasziou, P. and Del Mar, C. (1999). Individualised medication effectiveness tests in general practice. In: General Practice Evaluation Program Conference, Brisbane, QLD, Australia, (). 1999.

Single patient trials in general practice

Nikles, C. J., Glasziou, P. P. and Del Mar, C. B. (1999). Single patient trials in general practice. In: General Practice Evaluation Program Conference Program & Abstracts. General Practice Evaluation Program Conference, Sheraton, Brisbane, (97). 6-7 May 1999.

Infections in renal transplant recipients

Moses, Diana, Nikles, Jane, Leong, Geoff and Hardie, Ian (1983). Infections in renal transplant recipients. In: Proceedings of the Meeting of the Surgical Research Society of Australasia. Meeting of the Surgical Research Society of Australasia, Perth, Western Australia, (361-361). 14-16 October 1982. doi:10.1111/j.1445-2197.1983.tb02463.x

N-of-1 trials of stimulants versus placebo for paediatric traumatic brain injury: Pilot Final Report

McKinlay, L., Mitchell, G., Nikles, J., Lloyd, O., Waugh, M. and Epps, A. (2010) N-of-1 trials of stimulants versus placebo for paediatric traumatic brain injury: Pilot Final Report :

Using n-of-1 trials as a diagnostic clinical tool

Nikles, Jane (2006). Using n-of-1 trials as a diagnostic clinical tool PhD Thesis, Population Health, The University of Queensland.

An economic evaluation of n-of-1 trials in clinical practice : Final report

Clark, R., Del Mar, C. B., Mitchell, G. K., Nikles, C. J., Scuffham, P. and Yelland, M. (2006) An economic evaluation of n-of-1 trials in clinical practice : Final report Canberra, ACT, Australia: Australian Health Ministers Advisory Council

Individualised Medical Effectivenss Tests comparing Dexamphetamine or Methylphenidate with placebo for the treatment of Attention- Deficit Hyperactivity Disorder in General Practice

Mitchell, G. K., Nikles, C.J., Duggan, C., Glasziou, P. P. and Del Mar, C. B. (2002) Individualised Medical Effectivenss Tests comparing Dexamphetamine or Methylphenidate with placebo for the treatment of Attention- Deficit Hyperactivity Disorder in General Practice Australia: University of Queensland