An Infectious Diseases Physician and Microbiologist, Dr Paul Griffin was appointed as the Director of Infectious Diseases at Mater Health Services in 2013. In addition Dr Griffin continues appointments as Principal Investigator at Q-Pharm, as Visiting Scientist/Honorary Research Fellow at Mater Medical Research Institute and Queensland Institute of Medical Research, and also as Senior Lecturer at the University of Queensland.
Dr Paul Griffin's primary research interests include clinical trials in the field of infectious diseases particularly malaria human challenge and transmission blocking studies, as well as the detection of antibiotic resistance particularly VRE by mass spectrometry in the clinical microbiology laboratory.
Evans, Thomas G, Bussey, Louise, Eagling-Vose, Elizabeth, Rutkowski, Kathryn, Ellis, Chris, Argent, Chris, Griffin, Paul, Kim, Joshua, Thackwray, Susan, Shakib, Sepehr, Doughty, Julia, Gillies, John, Wu, Jian, Druce, Julian, Pryor, Melinda and Gilbert, Sarah (2022). Efficacy and safety of a universal influenza A vaccine (MVA-NP+M1) in adults when given after seasonal quadrivalent influenza vaccine immunisation (FLU009): a phase 2b, randomised, double-blind trial. The Lancet Infectious Diseases, 22 (6), 857-866. doi: 10.1016/S1473-3099(21)00702-7
Journal Article: Safety, tolerability, pharmacokinetics, and pharmacodynamics of coadministered Ruxolitinib and Artemether-Lumefantrine in healthy adults
Chughlay, M. Farouk, Barnes, Karen I., El Gaaloul, Myriam, Abla, Nada, Möhrle, Jörg J., Griffin, Paul, van Giersbergen, Paul, Reuter, Stephanie E., Schultz, Hayley B., Kress, Anita, Tapley, Peter, Webster, Rebecca A., Wells, Timothy, McCarthy, James S., Barber, Bridget E., Marquart, Louise, Boyle, Michelle J., Engwerda, Christian R. and Chalon, Stephan (2022). Safety, tolerability, pharmacokinetics, and pharmacodynamics of coadministered Ruxolitinib and Artemether-Lumefantrine in healthy adults. Antimicrobial Agents and Chemotherapy, 66 (1) e01584-21, e0158421. doi: 10.1128/AAC.01584-21
Journal Article: Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine
Webster, Rebecca, Sekuloski, Silvana, Odedra, Anand, Woolley, Stephen, Jennings, Helen, Amante, Fiona, Trenholme, Katharine R., Healer, Julie, Cowman, Alan F., Eriksson, Emily M., Sathe, Priyanka, Penington, Jocelyn, Blanch, Adam J., Dixon, Matthew W. A., Tilley, Leann, Duffy, Michael F., Craig, Alister, Storm, Janet, Chan, Jo-Anne, Evans, Krystal, Papenfuss, Anthony T., Schofield, Louis, Griffin, Paul, Barber, Bridget E., Andrew, Dean, Boyle, Michelle J., de Labastida Rivera, Fabian, Engwerda, Christian and McCarthy, James S. (2021). Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine. BMC Medicine, 19 (1) 293, 293. doi: 10.1186/s12916-021-02150-x
(2019–2022) Children's Health Queensland Hospital and Health Service
Eisemann, Jared E. and Griffin, Paul M. (2017). Diloxanide furoate. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 3195-3199) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Doshi, Jaslyn and Griffin, Paul M. (2017). Furazolidone (furazolidine). Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 3187-3194) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Griffin, Paul M. and McCarthy, James (2017). Niclosamide. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 3405-3409) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Griffin, Paul (2014). Australian Bat Lyssavirus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) edited by Victor L. Yu, Rainer Weber and Didier Raoult. Pittsburgh, PA, USA: Antimicrobe.
Griffin, Paul (2014). Barmah Forest Virus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) edited by Victor L. Yu, Rainer Weber and Didier Raoult. Pittsburgh, PA, USA: Antimicrobe.
Griffin, P. M. (2014). Menangle. Infectious Disease and Antimicrobial Agents. (pp. 1-1) Pittsburgh, PA, United States: Antimicrobe.
Griffin, Paul (2014). Ross River Virus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) Pittsburgh, PA, United States: Antimicrobe.
Griffin, Paul M. (2010). Diloxanide furoate. Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. (pp. 2121-2124) edited by M. Lindsay Grayson, Suzanne M. Crowe, James S. McCarthy, John Mills, Johan W. Mouton, S. Ragnar Norrby, David L. Paterson and Michael A. Pfaller. Boca Raton, FL, USA: CRC Press. doi: 10.1201/b13787-206
Griffin, Paul M. (2010). Furazolidone (furazolidine). Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. (pp. 2114-2120) edited by M. Lindsay Grayson, Suzanne M. Crowe, James S. McCarthy, John Mills, Johan W. Mouton, S. Ragnar Norrby, David L. Paterson and Michael A. Pfaller. Boca Raton, FL, USA: CRC Press. doi: 10.1201/b13787-205
Griffin, Paul M. and McCarthy, James (2010). Niclosamide. Kucers' the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs. (pp. 2293-2296) edited by M. Lindsay Grayson, Suzanne M. Crowe, James S. McCarthy, John Mills, Johan W. Mouton, S. Ragnar Norrby, David L. Paterson and Michael A. Pfaller. Boca Raton, FL, United States: CRC Press. doi: 10.1201/b13787-232
Evans, Thomas G, Bussey, Louise, Eagling-Vose, Elizabeth, Rutkowski, Kathryn, Ellis, Chris, Argent, Chris, Griffin, Paul, Kim, Joshua, Thackwray, Susan, Shakib, Sepehr, Doughty, Julia, Gillies, John, Wu, Jian, Druce, Julian, Pryor, Melinda and Gilbert, Sarah (2022). Efficacy and safety of a universal influenza A vaccine (MVA-NP+M1) in adults when given after seasonal quadrivalent influenza vaccine immunisation (FLU009): a phase 2b, randomised, double-blind trial. The Lancet Infectious Diseases, 22 (6), 857-866. doi: 10.1016/S1473-3099(21)00702-7
Chughlay, M. Farouk, Barnes, Karen I., El Gaaloul, Myriam, Abla, Nada, Möhrle, Jörg J., Griffin, Paul, van Giersbergen, Paul, Reuter, Stephanie E., Schultz, Hayley B., Kress, Anita, Tapley, Peter, Webster, Rebecca A., Wells, Timothy, McCarthy, James S., Barber, Bridget E., Marquart, Louise, Boyle, Michelle J., Engwerda, Christian R. and Chalon, Stephan (2022). Safety, tolerability, pharmacokinetics, and pharmacodynamics of coadministered Ruxolitinib and Artemether-Lumefantrine in healthy adults. Antimicrobial Agents and Chemotherapy, 66 (1) e01584-21, e0158421. doi: 10.1128/AAC.01584-21
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine
Webster, Rebecca, Sekuloski, Silvana, Odedra, Anand, Woolley, Stephen, Jennings, Helen, Amante, Fiona, Trenholme, Katharine R., Healer, Julie, Cowman, Alan F., Eriksson, Emily M., Sathe, Priyanka, Penington, Jocelyn, Blanch, Adam J., Dixon, Matthew W. A., Tilley, Leann, Duffy, Michael F., Craig, Alister, Storm, Janet, Chan, Jo-Anne, Evans, Krystal, Papenfuss, Anthony T., Schofield, Louis, Griffin, Paul, Barber, Bridget E., Andrew, Dean, Boyle, Michelle J., de Labastida Rivera, Fabian, Engwerda, Christian and McCarthy, James S. (2021). Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine. BMC Medicine, 19 (1) 293, 293. doi: 10.1186/s12916-021-02150-x
Chappell, Keith J., Mordant, Francesca L., Li, Zheyi, Wijesundara, Danushka K., Ellenberg, Paula, Lackenby, Julia A., Cheung, Stacey T. M., Modhiran, Naphak, Avumegah, Michael S., Henderson, Christina L., Hoger, Kym, Griffin, Paul, Bennet, Jillian, Hensen, Luca, Zhang, Wuji, Nguyen, Thi H. O., Marrero-Hernandez, Sara, Selva, Kevin J., Chung, Amy W., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D., Hogarth, P Mark, Kedzierska, Katherine ... Munro, Trent P. (2021). Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. The Lancet Infectious Diseases, 21 (10), 1383-1394. doi: 10.1016/S1473-3099(21)00200-0
Yamada, Miko, Miller, Dennis M., Lowe, Melinda, Rowe, Casey, Wood, Dominic, Soyer, H. Peter, Byrnes-Blake, Kelly, Parrish-Novak, Julia, Ishak, Laura, Olson, James M., Brandt, Gordon, Griffin, Paul, Spelman, Lynda and Prow, Tarl W. (2021). A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients. Contemporary Clinical Trials Communications, 23 100830, 1-6. doi: 10.1016/j.conctc.2021.100830
Krishnan, Ravi, Duiker, Melanie, Rudd, Penny A., Skerrett, Donna, Pollard, James G. D., Siddel, Carolyn, Rifat, Rifat, Ng, Jennifer H. K., Georgius, Peter, Hererro, Lara J. and Griffin, Paul (2021). Pentosan polysulfate sodium for Ross River virus-induced arthralgia: a phase 2a, randomized, double-blind, placebo-controlled study. BMC Musculoskeletal Disorders, 22 (1) 271. doi: 10.1186/s12891-021-04123-w
McCarthy, James S., Abd-Rahman, Azrin N., Collins, Katharine A., Marquart, Louise, Griffin, Paul, Kummel, Anne, Fuchs, Aline, Winnips, Cornelis, Mishra, Vishal, Csermak-Renner, Katalin, Jain, J. Prakash and Gandhi, Preetam (2021). Defining the antimalarial activity of cipargamin in healthy volunteers experimentally infected with blood-stage Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 65 (2) e01423-20. doi: 10.1128/aac.01423-20
Phase 1-2 trial of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine
Keech, Cheryl, Albert, Gary, Cho, Iksung, Robertson, Andreana, Reed, Patricia, Neal, Susan, Plested, Joyce S., Zhu, Mingzhu, Cloney-Clark, Shane, Zhou, Haixia, Smith, Gale, Patel, Nita, Frieman, Matthew B., Haupt, Robert E., Logue, James, McGrath, Marisa, Weston, Stuart, Piedra, Pedro A., Desai, Chinar, Callahan, Kathleen, Lewis, Maggie, Price-Abbott, Patricia, Formica, Neil, Shinde, Vivek, Fries, Louis, Lickliter, Jason D., Griffin, Paul, Wilkinson, Bethanie and Glenn, Gregory M. (2020). Phase 1-2 trial of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine. The New England Journal of Medicine, 383 (24), 2320-2332. doi: 10.1056/NEJMoa2026920
Aliprantis, Antonios O., Shaw, Christine A., Griffin, Paul, Farinola, Nicholas, Railkar, Radha A., Cao, Xin, Liu, Wen, Sachs, Jeffrey R., Swenson, Christine J., Lee, Heather, Cox, Kara S., Spellman, Daniel S., Winstead, Colleen J., Smolenov, Igor, Lai, Eseng, Zaks, Tal, Espeseth, Amy S. and Panther, Lori (2020). A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults. Human Vaccines and Immunotherapeutics, 17 (5), 1-14. doi: 10.1080/21645515.2020.1829899
Henderson, A., Paterson, D. L., Chatfield, M. D., Tambyah, P. A., Lye, D. C., De, P. P., Lin, R. T. P., Chew, K. L., Yin, M., Lee, T. H., Yilmaz, M., Cakmak, R., Alenazi, T. H., Arabi, Y. M., Falcone, M., Bassetti, M., Righi, E., Rogers, B.A., Kanj, S. S., Bhally, H., Iredell, J., Mendelson, M., Boyles, T. H., Looke, D. F. M., Runnegar, N. J., Miyakis, S., Walls, G., AI Khamis, M., Zikri, A. ... For the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2020). Association between minimum inhibitory concentration, beta-lactamase genes and mortality for patients treated with piperacillin/tazobactam or meropenem from the MERINO study. Clinical Infectious Diseases, 73 (11), e3842-e3850. doi: 10.1093/cid/ciaa1479
Lickliter, Jason, Kanceva, Radmila, Vincent, Emmanuelle, Schueler, Armin, Harrison-Moench, Eleanor, Yue, Corinne Seng, Stahl, Michael, Ullmann, Martin, Ghori, Vishal and Griffin, Paul (2020). Pharmacokinetics and pharmacodynamics of a proposed pegfilgrastim biosimilar MSB11455 versus the reference pegfilgrastim Neulasta® in healthy subjects: a randomized, double-blind trial. Clinical Therapeutics, 42 (8), 1508-1518.e1. doi: 10.1016/j.clinthera.2020.05.020
Collins, Katharine A., Abd-Rahman, Azrin N., Marquart, Louise, Ballard, Emma, Gobeau, Nathalie, Griffin, Paul, Chalon, Stephan, Möhrle, Jörg J. and McCarthy, James S. (2020). Antimalarial activity of artefenomel against asexual parasites and transmissible gametocytes during experimental blood-stage Plasmodium vivax infection. The Journal of Infectious Diseases, 225 (6), 1062-1069. doi: 10.1093/infdis/jiaa287
Playford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6
McCarthy, James S., Rückle, Thomas, Elliott, Suzanne L., Ballard, Emma, Collins, Katharine A., Marquart, Louise, Griffin, Paul, Chalon, Stephan and Möhrle, Jörg J. (2020). A single-dose combination study with the experimental antimalarials artefenomel and DSM265 to determine safety and antimalarial activity against blood-stage Plasmodium falciparum in healthy volunteers. Antimicrobial Agents and Chemotherapy, 64 (1) e01371-19, e01371-19. doi: 10.1128/AAC.01371-19
Chandra, Janin, Woo, Wai-Ping, Dutton, Julie L., Xu, Yan, Li, Bo, Kinrade, Sally, Druce, Julian, Finlayson, Neil, Griffin, Paul, Laing, Kerry J., Koelle, David M. and Frazer, Ian H. (2019). Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: a randomized double blinded phase I/IIa trial. PLoS One, 14 (12) e0226320, 1-20. doi: 10.1371/journal.pone.0226320
Collins, Katharine A., Rueckle, Thomas, Elliott, Suzanne, Marquart, Louise, Ballard, Emma, Chalon, Stephan, Griffin, Paul, Moehrle, Joern J. and McCarthy, James S. (2019). DSM265 at 400 milligrams clears asexual stage parasites but not mature gametocytes from the blood of healthy subjects experimentally infected with Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 63 (4) e01837-18. doi: 10.1128/AAC.01837-18
Manton, Kerry J., Gauld, Cassandra S., White, Katherine M., Griffin, Paul M. and Elliott, Suzanne L. (2019). Qualitative study investigating the underlying motivations of healthy participants in phase I clinical trials. BMJ Open, 9 (1) e024224, e024224. doi: 10.1136/bmjopen-2018-024224
Playford, Elliott, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2019). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a randomised, first-in-human phase 1 study. SSRN Electronic Journal. doi: 10.2139/ssrn.3457427
Harris, Patrick N. A., Tambyah, Paul A., Lye, David C., Mo, Yin, Lee, Tau H., Yilmaz, Mesut, Alenazi, Thamer H., Arabi, Yaseen, Falcone, Marco, Bassetti, Matteo, Righi, Elda, Rogers, Benjamin A., Kanj, Souha, Bhally, Hasan, Iredell, Jon, Mendelson, Marc, Boyles, Tom H., Looke, David, Miyakis, Spiros, Walls, Genevieve, Al Khamis, Mohammed, Zikri, Ahmed, Crowe, Amy, Ingram, Paul, Daneman, Nick, Griffin, Paul, Athan, Eugene, Lorenc, Penelope, Baker, Peter ... MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2018). Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a randomized clinical trial. JAMA, 320 (10), 984-994. doi: 10.1001/jama.2018.12163
Proietto, Joseph, Malloy, Jaret, Zhuang, Dongliang, Arya, Mark, Cohen, Neale D., de Looze, Ferdinandus J., Gilfillan, Christopher, Griffin, Paul, Hall, Stephen, Nathow, Thomas, Oldfield, Geoffrey S., O'Neal, David N., Roberts, Adam, Stuckey, Bronwyn G. A., Yue, Dennis, Taylor, Kristin and Kim, Dennis (2018). Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial. Diabetologia, 61 (9), 1918-1922. doi: 10.1007/s00125-018-4677-0
Sekuloski, Silvana, Batzloff, Michael R., Griffin, Paul, Parsonage, William, Elliott, Suzanne, Hartas, Jon, O'Rourke, Peter, Marquart, Louise, Pandey, Manisha, Rubin, Fran A., Carapetis, Jonathan, McCarthy, James and Good, Michael F. (2018). Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial. PLoS One, 13 (7) e0198658, e0198658. doi: 10.1371/journal.pone.0198658
Fernando, Germain J. P., Hickling, Julian, Jayashi Flores, Cesar M., Griffin, Paul, Anderson, Christopher D., Skinner, S. Rachel, Davies, Cristyn, Witham, Katey, Pryor, Melinda, Bodle, Jesse, Rockman, Steve, Frazer, Ian H. and Forster, Angus H. (2018). Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™). Vaccine, 36 (26), 3779-3788. doi: 10.1016/j.vaccine.2018.05.053
Woodford, John, Shanks, G Dennis, Griffin, Paul, Chalon, Stephan and McCarthy, James (2018). The Dynamics of Liver Function Test Abnormalities after Malaria Infection: A Retrospective Observational Study. The American Journal of Tropical Medicine and Hygiene, 98 (4), 1113-1119. doi: 10.4269/ajtmh.17-0754
Griffin, Paul, Elliot, Suzanne, Krauer, Kenia, Davies, Cristyn, Skinner, Rachel, Anderson, Christopher D. and Forster, Anguis (2017). Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects. Vaccine, 35 (48), 6676-6684. doi: 10.1016/j.vaccine.2017.10.021
McCarthy, James S., Lotharius, Julie, Ruckle, Thomas, Chalon, Stephan, Phillips, Margaret A., Elliott, Suzanne, Sekuloski, Silvana, Griffin, Paul, Ng, Caroline L., Fidock, David A., Marquart, Louise, Williams, Noelle S., Gobeau, Nathalie, Bebrevska, Lidiya, Rosario, Maria, Marsh, Kennan and Mohrle, Jorg J. (2017). Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study. The Lancet Infectious Diseases, 17 (6), 626-635. doi: 10.1016/S1473-3099(17)30171-8
First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery
Bursle, Evan, Playford, E. Geoffrey, Coulter, Chris and Griffin, Paul (2017). First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery. Infection, Disease and Health, 22 (1), 1-5. doi: 10.1016/j.idh.2017.01.003
Plasmodium vivax controlled human malaria infection - progress and prospects
Payne, Ruth O., Griffin, Paul M., McCarthy, James S. and Draper, Simon J. (2016). Plasmodium vivax controlled human malaria infection - progress and prospects. Trends in Parasitology, 33 (2), 141-150. doi: 10.1016/j.pt.2016.11.001
Griffin, Paul, Pasay, Cielo, Elliott, Suzanne, Sekuloski, Silvana, Sikulu, Maggy, Hugo, Leon, Khoury, David, Cromer, Deborah, Davenport, Miles, Sattabongkot, Jetsumon, Ivinson, Karen, Ockenhouse, Christian and McCarthy, James (2016). Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission. PLoS Neglected Tropical Diseases, 10 (12) e0005139, e0005139. doi: 10.1371/journal.pntd.0005139
MALDI-TOF MS meets WGS in a VRE outbreak investigation
Schlebusch, S., Price, G. R., Gallagher, R. L., Horton-Szar, V., Elbourne, L. D. H., Griffin, P., Venter, D. J., Jensen, S. O. and van Hal, S. J. (2016). MALDI-TOF MS meets WGS in a VRE outbreak investigation. European Journal of Clinical Microbiology and Infectious Diseases, 36 (3), 1-5. doi: 10.1007/s10096-016-2824-4
McCarthy, James S., Ruckle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O'Rourke, Peter, Griffin, Paul, Marquart, Louise, van Huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study. Malaria Journal, 15 (469) 469, 469. doi: 10.1186/s12936-016-1511-3
McCarthy, James S., Baker, Mark, O'Rourke, Peter, Marquart, Louise, Griffin, Paul, van huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers. Journal of Antimicrobial Chemotherapy, 71 (9), 2620-2627. doi: 10.1093/jac/dkw174
Stanisic, Danielle I., Gerrard, John, Fink, James, Griffin, Paul M., Liu, Xue Q., Sundac, Lana, Sekuloski, Silvana, Rodriguez, Ingrid B., Pingnet, Jolien, Yang, Yuedong, Zhou, Yaoqi, Trenholme, Katharine R., Wang, Claire Y. T., Hackett, Hazel, Chan, Jo-Anne A., Langer, Christine, Hanssen, Eric, Hoffman, Stephen L., Beeson, James G., McCarthy, James S. and Good, Michael F. (2016). Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite. Infection and Immunity, 84 (9), 2689-2696. doi: 10.1128/IAI.00414-16
Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872
McCarthy, James S., Marquart, Louise, Sekuloski, Silvana, Trenholme, Katherine, Elliott, Suzanne, Griffin, Paul, Rockett, Rebecca, O'Rourke, Peter, Sloots, Theo, Angulo-Barturen, Inigo, Ferrer, Santiago, Jimenez-Diaz, Maria Belen, Martinez, Maria-Santos, van Huijsduijnen, Rob Hoof, Duparc, Stephan, Leroy, Didier, Wells, Timothy N. C., Baker, Mark and Mohrle, Jorg J. (2016). Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development. Antimicrobial Agents and Chemotherapy, 60 (6), 3669-3675. doi: 10.1128/AAC.02883-15
Gassiep, Ian, Armstrong, Mark, Van Havre, Zoe, Schlebusch, Sanmarie, McCormack, Joseph and Griffin, Paul (2015). Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study. Healthcare Infection, 20 (4), 115-123. doi: 10.1071/HI15013
Stein, Daniel S, Jain, Jay Prakash, Kangas, Michael, Lefèvre, Gilbert, Machineni, Surendra, Griffin, Paul and Lickliterf, Jason (2015). Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine. Antimicrobial Agents and Chemotherapy, 59 (6), 3493-3500. doi: 10.1128/AAC.00340-15
Delusions of disseminated fungosis
Gassiep, Ian and Griffin, Paul Matthew (2014). Delusions of disseminated fungosis. Case Reports in Infectious Diseases, 2014 (458028), 1-3. doi: 10.1155/2014/458028
Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report
Dang, Lily V., Byrom, Lisa, Muir, Jim and Griffin, Paul M. (2014). Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report. Infectious Diseases in Clinical Practice, 22 (5), e119-e121. doi: 10.1097/IPC.0000000000000182
Griffin, Paul M., Elliott, Suzanne L. and Manton, Kerry J. (2014). Fasting increases serum bilirubin levels in clinically normal, healthy males but not females: a retrospective study from phase I clinical trial participants. Journal of Clinical Pathology, 67 (6), 529-534. doi: 10.1136/jclinpath-2013-202155
Maldi in infection control (VRE)
Griffin, Paul (2014). Maldi in infection control (VRE). Pathology, 46, S45. doi: 10.1097/01.pat.0000443496.32732.1d
Experimentally induced blood-stage plasmodium vivax infection in healthy volunteers
McCarthy, James S., Griffin, Paul M., Sekuloski, Silvana, Bright, A. Taylor, Rockett, Rebecca, Looke, David, Elliott, Suzanne, Whiley, David, Sloots, Theo, Winzeler, Elizabeth A. and Trenholme, Katharine R. (2013). Experimentally induced blood-stage plasmodium vivax infection in healthy volunteers. Journal of Infectious Diseases, 208 (10), 1688-1694. doi: 10.1093/infdis/jit394
Rapid identification of VRE with MALDI-TOF MS
Griffin, Paul M., Price, Gareth R., Schooneveldt, Jacqueline M., Schlebusch, Sanmarié, Urbanski, Tess, Hamilton, Brett and Venter, Deon (2013). Rapid identification of VRE with MALDI-TOF MS. Pathology, 45, S57-S57. doi: 10.1097/01.pat.0000426852.32930.4a
Chronic urticaria following acute hepatitis A
Griffin, Paul M., Kevat, Dev A. S., McCarthy, James S. and Woods, Marion L. (2012). Chronic urticaria following acute hepatitis A. BMJ case reports, 2012 (sep18 1), bcr2012006479-bcr2012006479. doi: 10.1136/bcr-2012-006479
Griffin, Paul M., Price, Gareth R., Schooneveldt, Jacqueline M., Schlebusch, Sanmarie, Tilse, Martyn H., Urbanski, Tess, Hamilton, Brett and Venter, Deon (2012). Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry to identify vancomycin-resistant enterococci and investigate the epidemiology of an outbreak. Journal of Clinical Microbiology, 50 (9), 2918-2931. doi: 10.1128/JCM.01000-12
McCarthy, James S., Sekuloski, Silvana, Griffin, Paul M., Elliott, Suzanne, Douglas, Nanette, Peatey, Chris, Rockett, Rebecca, O'Rourke, Peter, Marquart, Louise, Hermsen, Cornelius, Duparc, Stephan, Moehrle, Joerg, Trenholme, Katharine R. and Humberstone, Andrew J. (2011). A pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs. PLoS ONE, 6 (8) e21914, e21914-1-e21914-8. doi: 10.1371/journal.pone.0021914
Griffin, Paul and McCarthy, James (2010). Malaria: Part 2. Medical Observer, 23-23.
Griffin, Paul and McCarthy, James (2010). Malaria: Part 1. Medical Observer, 23-23.
Lickliter, Jason D., Griffin, Paul, Vincent, Emmanuelle, Schuler, Armin, Harrison-Moench, Eleanor, Stahl, Michael, El Bawab, Samer, Kanceva, Radmila and Gascon, Pere (2019). Pharmacokinetic/pharmacodynamic assessment of a proposed biosimilar MSB11455 versus the currently licensed pegfilgrastim: A randomized, double-blind trial. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, United States, 31May - 4 June, 2019. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/JCO.2019.37.15_suppl.e14514
Collins, Jon, Jones, Lori, Snyder, Michele, Sicard, Eric, Griffin, Paul, Webster, Lindsey, Fong, Regan, Coquery, Christine and Piscitelli, Stephen (2019). RVT-1401, A Novel Anti-FcRn Monoclonal Antibody, Is Well Tolerated in Healthy Subjects and Reduces Plasma IgG Following Subcutaneous or Intravenous Administration. 71st Annual Meeting of the American Academy of Neurology (AAN), Philadelphia, PA, United States, 4-10 May, 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins.
Yamada, M., Miller, D., Lowe, M., Rowe, C., Wood, D., Byrnes-Blake, K., Parrish-Novak, J., Ishak, L., Olson, J., Brandt, G., Griffin, P., Spleman, L. and Prow, T. (2018). A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer. International Investigative Dermatology (IID) Meeting, Orlando, FL, United States, 16-19 May 2018. New York, United States: Elsevier.
First-in-human phase 1 safety study of BLZ-100 in subjects with skin cancer
Spelman, L., Johnston, J., Prow, T., Yamada, M., Griffin, P., Wood, D. and Miller, D. (2016). First-in-human phase 1 safety study of BLZ-100 in subjects with skin cancer. Australasian College of Dermatologists 49th Annual Scientific Meeting, Perth, Australia, 14–17 May 2016. HOBOKEN: WILEY-BLACKWELL.
Pasay, Cielo J., Rockett, Rebecca, Sekuloski, Silvana, Griffin, Paul, Marquart, Louise, Peatey, Christopher, Wang, Claire Y. T., O'Rourke, Peter, Elliott, Suzanne, Baker, Mark, Möhrle, Jörg J. and McCarthy, James S. (2016). Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia. Cary, NC, United States: Oxford University Press. doi: 10.1093/infdis/jiw128
Stein, Daniel, Jain, Jay Prakash, Lickliter, Jason, Kangas, Michael, Machineri, Surendra and Griffin, Paul (2014). A phase 1 evaluation of the pharmacokinetic/pharmacodynamics interaction of the antimalarial agent KAE609 and piperaquine (PPQ). Challanges in malaria research: Core science and innovation, Oxford, United Kingdom, 22-24 September 2014. London, United Kingdom: BioMed Central. doi: 10.1186/1475-2875-13-S1-P85
Rapid Identification of Vancomycin Resistant Enterococci with Maldi-Tof Mass Spectrometry
Griffin, Paul, Price, Gareth, Hamilton, Brett, Schooneveldt, Jacqueline, Urbanski, Tess, Schlebusch, Sanmarie and Venter, Deon (2013). Rapid Identification of Vancomycin Resistant Enterococci with Maldi-Tof Mass Spectrometry. The Royal Australasian College of Physicians Future Directions in Health Congress 2013 (RACP), Perth WA, Australia, 26-29 May 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12153
(2019–2022) Children's Health Queensland Hospital and Health Service