The University of Queensland

Invasive pulmonary aspergillosis in critically ill patients

Blot, S. , Koulenti, Despoina and Dimopoulos, G. (2013). Invasive pulmonary aspergillosis in critically ill patients. Annual Update in Intensive Care and Emergency Medicine 2013. (pp. 63-75) edited by Jean-Louis Vincent. Berlin, Heidelberg: Springer. doi: https://doi.org/10.1007/978-3-642-35109-9

Risk factors

Gattarello, Simone, Koulenti, Despoina and Rello, Jordi (2013). Risk factors. Hospital-acquired Pneumonia. (pp. 6-16) edited by Ilias I. Siempos. London, United Kingdom: Future Medicine. doi: 10.2217/ebo.12.221

Symptoms, diagnosis and prognosis

Koulenti, Despoina and Tabah, Alexis (2013). Symptoms, diagnosis and prognosis. Hospital-acquired pneumonia. (pp. 33-48) edited by Ilias I. Siempos. London, United Kingdom: Future Medicine. doi: 10.2217/EBO.12.286

Hospital-Acquired Pneumonia Caused by Staphylococcus aureus

Koulenti, Despoina and Agbaht, Kemal (2007). Hospital-Acquired Pneumonia Caused by Staphylococcus aureus. Nosocomial Pneumonia: Strategies for Management. (pp. 107-129) Chichester, UK: John Wiley & Sons, Ltd.. doi: 10.1002/9780470518274.ch7

Sepsis in Obstetrics

Koulenti, D. and Correa, H. (2007). Sepsis in Obstetrics. Infectious Diseases in Critical Care.. (pp. 488-493) edited by Rello, J.,, Kollef, M., Díaz, E. and Rodríguez, A.. Berlin, Heidelberg: Springer. doi: 10.1007/978-3-540-34406-3_46

Novel Antimicrobial Agents for Gram-Negative Pathogens

Karvouniaris, Marios, Almyroudi, Maria Panagiota, Abdul-Aziz, Mohd Hafiz, Blot, Stijn, Paramythiotou, Elisabeth, Tsigou, Evdoxia and Koulenti, Despoina (2023). Novel Antimicrobial Agents for Gram-Negative Pathogens. Antibiotics, 12 (4) 761, 761. doi: 10.3390/antibiotics12040761

Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial

Chastre, Jean, François, Bruno, Bourgeois, Marc, Komnos, Apostolos, Ferrer, Ricard, Rahav, Galia, De Schryver, Nicolas, Lepape, Alain, Koksal, Iftihar, Luyt, Charles-Edouard, Sánchez-García, Miguel, Torres, Antoni, Eggimann, Philippe, Koulenti, Despoina, Holland, Thomas L., Ali, Omar, Shoemaker, Kathryn, Ren, Pin, Sauser, Julien, Ruzin, Alexey, Tabor, David E., Akhgar, Ahmad, Wu, Yuling, Jiang, Yu, DiGiandomenico, Antonio, Colbert, Susan, Vandamme, Drieke, Coenjaerts, Frank, Malhotra-Kumar, Surbhi ... Polk, Christopher (2022). Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial. Critical Care, 26 (1) 355. doi: 10.1186/s13054-022-04204-9

Impact of secondary sepsis on mortality in adult intensive care unit patients

Karvouniaris, Marios, Papadopoulos, Dimitrios, Koulenti, Despoina, Chatzimichail, Maria, Papamichalis, Panagiotis, Ntafoulis, Nikolaos, Valsamaki, Asimina, Katsiafylloudis, Perikles, Vaitsi, Eleni, Oikonomou, Katerina, Papapostolou, Evangelia, Xanthoudaki, Maria-Antonia, Papadogoulas, Antonios, Palli, Eleni, Poulakou, Garyphallia and Komnos, Apostolos (2022). Impact of secondary sepsis on mortality in adult intensive care unit patients. Intensive and Critical Care Nursing, 75 103345, 103345. doi: 10.1016/j.iccn.2022.103345

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

De Pascale, Gennaro, Antonelli, Massimo, Deschepper, Mieke, Arvaniti, Kostoula, Blot, Koen, Brown, Ben Creagh, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Dimopoulos, George, Eckmann, Christian, Francois, Guy, Girardis, Massimo, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovetsky, Fernando, Maseda, Emilio, Montravers, Philippe, Mikstacki, Adam, Paiva, José-Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Vogelaers, Dirk, Blot, Stijn, Lamrous, Amin, Lipovestky, Fernando, Rezende-Neto, Joao ... Davis, Noelle (2022). Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis. Intensive Care Medicine, 48 (11), 1593-1606. doi: 10.1007/s00134-022-06883-y

Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set

Conway Morris, Andrew, Kohler, Katharina, De Corte, Thomas, Ercole, Ari, De Grooth, Harm-Jan, Elbers, Paul W. G., Povoa, Pedro, Morais, Rui, Koulenti, Despoina, Jog, Sameer, Nielsen, Nathan, Jubb, Alasdair, Cecconi, Maurizio, De Waele, Jan, Bezzi, Marco, Gira, Alicia, Eller, Philipp, Hamid, Tarikul, Haque, Injamam Ull, De Buyser, Wim, Cudia, Antonella, De Backer, Daniel, Foulon, Pierre, Collin, Vincent, De Waele, Jan, Van Hecke, Jolien, De Waele, Elisabeth, Van Malderen, Claire, Mesland, Jean-Baptiste ... for the ESICM UNITE COVID investigators (2022). Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set. Critical Care, 26 (1) 249, 249. doi: 10.1186/s13054-022-04124-8

Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set

Conway Morris, Andrew, Kohler, Katharina, De Corte, Thomas, Ercole, Ari, De Grooth, Harm-Jan, Elbers, Paul W. G., Povoa, Pedro, Morais, Rui, Koulenti, Despoina, Jog, Sameer, Nielsen, Nathan, Jubb, Alasdair, Cecconi, Maurizio, De Waele, Jan, Bezzi, Marco, Gira, Alicia, Eller, Philipp, Hamid, Tarikul, Haque, Injamam Ull, De Buyser, Wim, Cudia, Antonella, De Backer, Daniel, Foulon, Pierre, Collin, Vincent, De Waele, Jan, Van Hecke, Jolien, De Waele, Elisabeth, Van Malderen, Claire, Mesland, Jean-Baptiste ... and for the ESICM UNITE COVID investigators (2022). Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set. Critical Care, 26 (1) 236, 1-13. doi: 10.1186/s13054-022-04108-8

Clinical features and outcomes of monobacterial and polybacterial episodes of ventilator‐associated pneumonia due to multidrug‐resistant​​​​​​​ Acinetobacter baumannii

Adukauskiene, Dalia, Ciginskiene, Ausra, Adukauskaite, Agne, Koulenti, Despoina and Rello, Jordi (2022). Clinical features and outcomes of monobacterial and polybacterial episodes of ventilator‐associated pneumonia due to multidrug‐resistant​​​​​​​ Acinetobacter baumannii. Antibiotics, 11 (7) 892, 1-13. doi: 10.3390/antibiotics11070892

Epidemiology of candidemia and fluconazole resistance in an ICU before and during the COVID-19 pandemic era

Routsi, Christina, Meletiadis, Joseph, Charitidou, Efstratia, Gkoufa, Aikaterini, Kokkoris, Stelios, Karageorgiou, Stavros, Giannopoulos, Charalampos, Koulenti, Despoina, Andrikogiannopoulos, Petros, Perivolioti, Efstathia, Argyropoulou, Athina, Vasileiadis, Ioannis, Vrioni, Georgia and Paramythiotou, Elizabeth (2022). Epidemiology of candidemia and fluconazole resistance in an ICU before and during the COVID-19 pandemic era. Antibiotics, 11 (6) 771, 1-12. doi: 10.3390/antibiotics11060771

Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: An international cohort study

Arvaniti, Kostoula, Dimopoulos, George, Antonelli, Massimo, Blot, Koen, Creagh-Brown, Ben, Deschepper, Mieke, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Eckmann, Christian, Einav, Sharon, Francois, Guy, Fjeldsoee-Nielsen, Hans, Girardis, Massimo, Jovanovic, Bojan, Lindner, Matthias, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovestky, Fernando, Makikado, Luis Daniel Umezawa, Maseda, Emilio, Mikstacki, Adam, Montravers, Philippe, Paiva, José Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Tomescu, Dana ... Blot, Stijn (2022). Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: An international cohort study. International Journal of Antimicrobial Agents, 60 (1) 106591, 106591. doi: 10.1016/j.ijantimicag.2022.106591

Current perspectives on the diagnosis and management of healthcare-associated ventriculitis and meningitis

Karvouniaris, Marios, Brotis, Alexandros, Tsiakos, Konstantinos, Palli, Eleni and Koulenti, Despoina (2022). Current perspectives on the diagnosis and management of healthcare-associated ventriculitis and meningitis. Infection and Drug Resistance, 15, 697-721. doi: 10.2147/IDR.S326456

An international survey on aminoglycoside practices in critically ill patients: the AMINO III study

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4

Antimicrobial stewardship in the ICU in COVID-19 times: the known unknowns

Schouten, Jeroen, De Waele, Jan, Lanckohr, Christian, Koulenti, Despoina, Haddad, Nisrine, Rizk, Nesrine, Sjövall, Fredrik and Kanj, Souha S. (2021). Antimicrobial stewardship in the ICU in COVID-19 times: the known unknowns. International Journal of Antimicrobial Agents, 58 (4) 106409, 106409. doi: 10.1016/j.ijantimicag.2021.106409

Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units

Vogelaers, Dirk, Blot, Stijn, Van den Berge, Andries, Montravers, Philippe, Francois, Guy, Labeau, Sonia, Blot, Koen, Deschepper, Mieke, Antonelli, Massimo, Lipman, Jeffrey, Lamrous, Amin, Pereyra, Cecilia, Lipovestky, Fernando, Koulenti, Despoina, De Waele, Jan, Rezende-Neto, Joao, Cardenas, Yenny, Vymazal, Tomas, Fjeldsoee-Nielsen, Hans, Kott, Matthias, Kostoula, Arvaniti, Javeri, Yash, Girardis, Massimo, Einav, Sharon, de Lange, Dylan, Makikado, Luis Daniel Umezawa, Mikstacki, Adam, Paiva, José-Artur, Tomescu, Dana ... Davis, Noelle (2021). Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units. Drugs, 81 (9), 1065-1078. doi: 10.1007/s40265-021-01534-w

How to measure microaspiration of subglottic secretions in clinical research in intubated patients?

Nseir, Saad, Koulenti, Despoina and Blot, Stijn (2021). How to measure microaspiration of subglottic secretions in clinical research in intubated patients?. Intensive and Critical Care Nursing, 63 103010, 1-2. doi: 10.1016/j.iccn.2020.103010

Nosocomial pneumonia in the era of multidrug-resistance: updates in diagnosis and management

Xu, Elena, Pérez-Torres, David, Fragkou, Paraskevi C., Zahar, Jean-Ralph and Koulenti, Despoina (2021). Nosocomial pneumonia in the era of multidrug-resistance: updates in diagnosis and management. Microorganisms, 9 (3) 534, 1-39. doi: 10.3390/microorganisms9030534

Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE study

Koulenti, Despoina, Armaganidis, Apostolos, Arvaniti, Kostoula, Blot, Stijn, Brun-Buisson, Christian, Deja, Maria, De Waele, Jan, Du, Bin, Dulhunty, Joel M., Garcia-Diaz, Julia, Judd, Matthew, Paterson, David L., Putensen, Christian, Reina, Rosa, Rello, Jordi, Restrepo, Marcos I., Roberts, Jason A., Sjovall, Fredrik, Timsit, Jean-Francois, Tsiodras, Sotirios, Zahar, Jean-Ralph, Zhang, Yuchi, Lipman, Jeffrey and On behalf of the Working Group on Pneumonia of the European Society of Intensive Care Medicine (2021). Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE study. Critical Care and Resuscitation, 23 (1), 59-66. doi: 10.51893/2021.1.oa5

Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans

Nepogodiev, Dmitri, Omar, Omar M, Glasbey, James C, Li, Elizabeth, Simoes, Joana FF, Abbott, Tom EF, Ademuyiwa, Adesoji O, Biccard, Bruce M, Chaudhry, Daoud, Davidson, Giana H, Di Saverio, Salomone, Gallo, Gaetano, Ghosh, Dhruv, Harrison, Ewen M, Hutchinson, Peter J, Kamarajah, Sivesh K, Keller, Deborah S, Lawani, Ismail, Minaya-Bravo, Ana, Moore, Rachel, Morton, Dion G, Ntirenganya, Faustin, Pata, Francesco, Pearse, Rupert M, la Medina, Antonio Ramos-De, Tabiri, Stephen, Venn, Mary L, Omar, Aneel Bhangu Omar M, Bhangu, Aneel ... COVIDSurg Collaborative (2020). Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans. British Journal of Surgery, 107 (11), 1440-1449. doi: 10.1002/bjs.11746

Nosocomial pneumonia diagnosis revisited

Koulenti, Despoina, Zhang, Yuchi and Fragkou, Paraskevi C. (2020). Nosocomial pneumonia diagnosis revisited. Current Opinion in Critical Care, 26 (5), 442-449. doi: 10.1097/MCC.0000000000000756

Pandrug-resistant Acinetobacter baumannii treatment: still a debatable topic with no definite solutions

Papathanakos, Georgios, Andrianopoulos, Ioannis, Papathanasiou, Athanasios, Koulenti, Despoina, Gartzonika, Konstantina and Koulouras, Vasilios (2020). Pandrug-resistant Acinetobacter baumannii treatment: still a debatable topic with no definite solutions. The Journal of antimicrobial chemotherapy, 75 (10), 3081-3081. doi: 10.1093/jac/dkaa264

Editorial for special issue “multidrug-resistant pathogens”

Koulenti, Despoina, Fragkou, Paraskevi C. and Tsiodras, Sotirios (2020). Editorial for special issue “multidrug-resistant pathogens”. Microorganisms, 8 (9) 1383, 1383-15. doi: 10.3390/microorganisms8091383

Evaluation of the quality of evidence supporting guideline recommendations for the nutritional management of critically ill adults

Xu, Elena, Tejada, Sofia, Solé-Lleonart, Candela, Campogiani, Laura, Valenzuela-Sanchez, Francisco, Koulenti, Despoina and Rello, Jordi (2020). Evaluation of the quality of evidence supporting guideline recommendations for the nutritional management of critically ill adults. Clinical Nutrition ESPEN, 39, 144-149. doi: 10.1016/j.clnesp.2020.07.004

Quality of evidence supporting surviving sepsis campaign recommendations

Rello, Jordi, Tejada, Sofia, Xu, Elena, Solé-Lleonart, Candela, Campogiani, Laura, Koulenti, Despoina, Ferreira-Coimbra, João and Lipman, Jeff (2020). Quality of evidence supporting surviving sepsis campaign recommendations. Anaesthesia Critical Care and Pain Medicine, 39 (4), 497-502. doi: 10.1016/j.accpm.2020.06.015

Pathogenesis-targeted preventive strategies for multidrug resistant ventilator-associated pneumonia: a narrative review

Cotoia, Antonella, Spadaro, Savino, Gambetti, Guido, Koulenti, Despoina and Cinnella, Gilda (2020). Pathogenesis-targeted preventive strategies for multidrug resistant ventilator-associated pneumonia: a narrative review. Microorganisms, 8 (6) 821, 821. doi: 10.3390/microorganisms8060821

Patterns in the epidemiology of candidemia as a consequence of antibiotic and antifungal exposure

Koulenti, Despoina and Blot, Stijn (2020). Patterns in the epidemiology of candidemia as a consequence of antibiotic and antifungal exposure. Burns, 46 (2), 500-501. doi: 10.1016/j.burns.2019.11.010

Colistin-resistant acinetobacter baumannii bacteremia: a serious threat for critically ill patients

Papathanakos, Georgios, Andrianopoulos, Ioannis, Papathanasiou, Athanasios, Priavali, Efthalia, Koulenti, Despoina and Koulouras, Vasilios (2020). Colistin-resistant acinetobacter baumannii bacteremia: a serious threat for critically ill patients. Microorganisms, 8 (2) 287, 287. doi: 10.3390/microorganisms8020287

Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?

Koulenti, Despoina, Arvaniti, Kostoula, Judd, Mathew, Lalos, Natasha, Tjoeng, Iona, Xu, Elena, Armaganidis, Apostolos and Lipman, Jeffrey (2020). Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?. Antibiotics, 9 (2) 51, 51. doi: 10.3390/antibiotics9020051

Emerging treatment options for infections by multidrug-resistant gram-positive microorganisms

Koulenti, Despoina, Xu, Elena, Song, Andrew, Mok, Isaac Yin Sum , Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Tsiodras, Sotirios and Lipman, Jeffrey (2020). Emerging treatment options for infections by multidrug-resistant gram-positive microorganisms. Microorganisms, 8 (2), 1-40. doi: 10.3390/microorganisms8020191

Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project

Blot, Stijn, Antonelli, Massimo, Arvaniti, Kostoula, Blot, Koen, Creagh-Brown, Ben, de Lange, Dylan, De Waele, Jan, Deschepper, Mieke, Dikmen, Yalim, Dimopoulos, George, Eckmann, Christian, Francois, Guy, Girardis, Massimo, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovestky, Fernando, Maseda, Emilio, Montravers, Philippe, Mikstacki, Adam, Paiva, Jose-Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Vogelaers, Dirk, Lamrous, Amin, Rezende-Neto, Joao, Cardenas, Yenny, Vymazal, Tomas ... Davis, Noelle (2019). Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project. Intensive Care Medicine, 45 (12), 1703-1717. doi: 10.1007/s00134-019-05819-3

Diagnosing invasive pulmonary aspergillosis in ICU patients: putting the puzzle together

Blot, Stijn, Rello, Jordi and Koulenti, Despoina (2019). Diagnosing invasive pulmonary aspergillosis in ICU patients: putting the puzzle together. Current Opinion in Critical Care, 25 (5), 430-437. doi: 10.1097/MCC.0000000000000637

Lefamulin. Comment on: “Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms, 2019, 7, 270”

Koulenti, Despoina, Xu, Elena, Yin Sum Mok, Isaac, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Lefamulin. Comment on: “Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms, 2019, 7, 270”. Microorganisms, 7 (10) 386, 386. doi: 10.3390/microorganisms7100386

Novel antibiotics for multidrug-resistant gram-positive microorganisms

Koulenti, Despoina, Xu, Elena, Mok, Isaac Yin Sum, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Novel antibiotics for multidrug-resistant gram-positive microorganisms. Microorganisms, 7 (8), 270. doi: 10.3390/microorganisms7080270

Factors associated with ventilator-associated events: an international multicenter prospective cohort study

Rello, Jordi, Ramírez-Estrada, Sergio, Romero, Anabel, Arvaniti, Kostoula, Koulenti, Despoina, Nseir, Saad, Oztoprak, Nefise, Bouadma, Lila, Vidaur, Loreto, Lagunes, Leonel, Peña-López, Yolanda, Almirante, Benito, Bastug, Aliye, Bassetti, Mateo, Bozkurt, Ilkay, Dimopoulos, George, Inan, Asuman, Oikonomou, Marina, Poulakou, Garyphallia, Thompson, David, Torrivilla, Estefania, Totorika, Izarne and Varghese, Vipin (2019). Factors associated with ventilator-associated events: an international multicenter prospective cohort study. European Journal of Clinical Microbiology and Infectious Diseases, 38 (9), 1693-1699. doi: 10.1007/s10096-019-03596-x

The role of minocycline in the treatment of nosocomial infections caused by multidrug, extensively drug and randrug resistant Acinetobacter baumannii: a systematic review of clinical evidence

Fragkou, Paraskevi C., Poulakou, Garyfallia, Blizou, Andromachi, Blizou, Myrto, Rapti, Vasiliki, Karageorgopoulos, Drosos E., Koulenti, Despoina, Papadopoulos, Antonios, Matthaiou, Dimitrios K. and Tsiodras, Sotirios (2019). The role of minocycline in the treatment of nosocomial infections caused by multidrug, extensively drug and randrug resistant Acinetobacter baumannii: a systematic review of clinical evidence. Microorganisms, 7 (6) 159, 159. doi: 10.3390/microorganisms7060159

Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2)

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2). European Journal of Clinical Microbiology and Infectious Diseases, 38 (4), 649-649. doi: 10.1007/s10096-019-03518-x

The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?. European Journal of Clinical Microbiology & Infectious Diseases, 38 (4), 637-647. doi: 10.1007/s10096-019-03486-2

Pharmacokinetic evaluation of linezolid administered intravenously in obese patients with pneumonia

Xie, Feifan, Mantzarlis, Konstantinos, Malliotakis, Polychronis, Koulouras, Vasileios, Degroote, Sophie, Koulenti, Despoina, Blot, Stijn, Boussery, Koen, Van Bocxlaer, Jan, Colin, Pieter and LIMOP study collaborators (2019). Pharmacokinetic evaluation of linezolid administered intravenously in obese patients with pneumonia. Journal of Antimicrobial Chemotherapy, 74 (3), 667-674. doi: 10.1093/jac/dky500

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669

Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?

Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019). Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 (3), 211-224. doi: 10.1016/j.ijantimicag.2018.10.011

Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Abbott, T. E.F., Patel, A., Ahmed, Tahania, Pearse, Rupert M., Greaves, K. E., Haddow, James, Futier, Emmanuel, Biais, Matthieu, Slim, Karem, Beattie, Scott, Clavien, Pierre-Alain, Demartines, Nicolas, Fleisher, Lee A., Grocott, Mike, Hoeft, Andreas, Holt, Peter, Moreno, Rui, Pritchard, Naomi, Rhodes, Andrew, Wijeysundera, Duminda, Wilson, Matt, Everingham, Kirsty, Hewson, Russell, Januszewska, Marta, Phull, Mandeep-Kaur, Halliwell, Richard, Cope, Jennifer, Shulman, Mark, Myles, Paul ... International Surgical Outcomes Study (ISOS) group (2019). Prospective observational cohort study on grading the severity of postoperative complications in global surgery research. British Journal of Surgery, 106 (2), e73-e80. doi: 10.1002/bjs.11025

Microbial cause of ICU-acquired pneumonia: hospital-acquired pneumonia versus ventilator-associated pneumonia

Luyt, Charles-Edouard, Hékimian, Guillaume, Koulenti, Despoina and Chastre, Jean (2018). Microbial cause of ICU-acquired pneumonia: hospital-acquired pneumonia versus ventilator-associated pneumonia. Current Opinion in Critical Care, 24 (5), 332-338. doi: 10.1097/MCC.0000000000000526

Assessing predictive accuracy for outcomes of ventilator-associated events in an international cohort: the EUVAE study

Ramírez-Estrada, Sergio, Lagunes, Leonel, Peña-López, Yolanda, Vahedian-Azimi, Amir, Nseir, Saad, Arvaniti, Kostoula, Bastug, Aliye, Totorika, Izarne, Oztoprak, Nefise, Bouadma, Lilla, Koulenti, Despoina, Rello, Jordi and EU-VAE Study Investigators Group (2018). Assessing predictive accuracy for outcomes of ventilator-associated events in an international cohort: the EUVAE study. Intensive Care Medicine, 44 (8), 1212-1220. doi: 10.1007/s00134-018-5269-7

Candida burn wound sepsis: The "holy trinity" of management

Matthaiou, Dimitrios K., Blot, Stijn and Koulenti, Despoina (2018). Candida burn wound sepsis: The "holy trinity" of management. Intensive and Critical Care Nursing, 46, 4-5. doi: 10.1016/j.iccn.2018.02.001

Nebulization of antimicrobial agents in mechanically ventilated adults in 2017: an international cross-sectional survey

Alves, Joana, Alp, Emine, Koulenti, Despoina, Zhang, Zhongheng, Ehrmann, Stephan, Blot, Stijn, Bassetti, Matteo, Conway-Morris, Andrew, Reina, Rosa, Teran, Enrique, Sole-Lleonart, Candela, Ruiz-Rodríguez, Maria, Rello, Jordi and SANEME-2 Investigators (2018). Nebulization of antimicrobial agents in mechanically ventilated adults in 2017: an international cross-sectional survey. European Journal of Clinical Microbiology & Infectious Diseases, 37 (4), 785-794. doi: 10.1007/s10096-017-3175-5

The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

Abbott, T. E. F., Ahmad, T., Phull, M. K., Fowler, A. J., Hewson, R., Biccard, B. M., Chew, M. S., Gillies, M., Pearse, R. M., International Surgical Outcomes Study (ISOS) group and Koulenti, Despoina (2018). The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis. British Journal of Anaesthesia, 120 (1), 146-155. doi: 10.1016/j.bja.2017.08.002

The CVC and CRBSI: don’t use it and lose it!

Laupland, K. B., Koulenti, D. and Schwebel, C. (2017). The CVC and CRBSI: don’t use it and lose it!. Intensive Care Medicine, 44 (2), 1-3. doi: 10.1007/s00134-017-5033-4

Evaluating rates of ventilator-associated pneumonia: consider patient, organizational & educational risk factors

Koulenti, Despoina, Boulanger, Carole and Blot, Stijn (2017). Evaluating rates of ventilator-associated pneumonia: consider patient, organizational & educational risk factors. Indian Journal of Medical Research, 145 (5), 697-698. doi: 10.4103/ijmr.IJMR_435_17

Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery

Ahmad, T., Bouwman, R. A., Grigoras, I., Aldecoa, C., Hofer, C., Hoeft, A., Holt, P., Buhre, W., Pearse, Rupert M., Clavien, Pierre-Alain, Demartines, Nicolas, Grocott, Mike, Haddow, James, Holt, Peter, Moreno, Rui, Pritchard, Naomi, Rhodes, Andrew, Wilson, Matt, Ahmed, Tahania, Halliwell, Richard, Shulman, Mark, Myles, Paul, Schmid, Werner, Hiesmayr, Michael, Wouters, Patrick, De Hert, Stefan, Lobo, Suzana, Beattie, Scott, Wijeysundera, Duminda ... on behalf the International Surgical Outcomes Study (ISOS) group (2017). Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery. British Journal of Anaesthesia, 119 (2), 258-266. doi: 10.1093/bja/aex185

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

Kahan, Brennan C., Koulenti, Desponia, Arvaniti, Kostoula, Beavis, Vanessa, Campbell, Douglas, Chan, Matthew, Moreno, Rui, Pearse, Rupert M. and The International Surgical Outcomes Study (ISOS) group (2017). Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries. Intensive Care Medicine, 43 (7), 971-979. doi: 10.1007/s00134-016-4633-8

The authors reply

Arvaniti, Kostoula, Lathyris, Dimitrios, Blot, Stijin, Apostolidou-Kiouti, Fani, Koulenti, Despoina and Haidich, Anna-Bettina (2017). The authors reply. Critical Care Medicine, 45 (7), E735-E736. doi: 10.1097/CCM.0000000000002442

What we learned from the EU-VAP/CAP Study for severe pneumonia

Leoni, Davide, Blot, Stijn, Tsigou, Evdoxia and Koulenti, Despoina (2017). What we learned from the EU-VAP/CAP Study for severe pneumonia. Clinical Pulmonary Medicine, 24 (3), 112-120. doi: 10.1097/CPM.0000000000000204

Cumulative Evidence of Randomized Controlled and Observational Studies on Catheter-Related Infection Risk of Central Venous Catheter Insertion Site in ICU Patients: A Pairwise and Network Meta-Analysis

Arvaniti, Kostoula, Lathyris, Dimitrios, Blot, Stijn, Apostolidou-Kiouti, Fani, Koulenti, Despoina and Haidich, Anna-Bettina (2017). Cumulative Evidence of Randomized Controlled and Observational Studies on Catheter-Related Infection Risk of Central Venous Catheter Insertion Site in ICU Patients: A Pairwise and Network Meta-Analysis. Critical Care Medicine, 45 (4), e437-e448. doi: 10.1097/CCM.0000000000002092

Improved survival among ICU-hospitalized patients with community-acquired pneumonia by unidentified organisms: a multicenter case–control study

Rello, J., Diaz, E., Mañez, R., Sole-Violan, J., Valles, J., Vidaur, L., Zaragoza, R., Gattarello, S., Alvarez, B., Alvarez, L., Blanquer, J., Blasco, Ma, Borges-Sa, M., Bouza, E., Bunsow, E., Catalan, M., Diaz, E., Garnacho, J., Koulenti, D., Lisboa, T., Lopez, D., Lopez-Pueyo, Mj, Lucena, F., Luque, P., Mañez, R., Martin, A., Pereira, J., Rello, J., Jorda, R. ... Zaragoza, R. (2017). Improved survival among ICU-hospitalized patients with community-acquired pneumonia by unidentified organisms: a multicenter case–control study. European Journal of Clinical Microbiology and Infectious Diseases, 36 (1), 123-130. doi: 10.1007/s10096-016-2779-5

Optimizing educational initiatives to prevent ventilator-associated complications

Blot, Stijn, Koulenti, Despoina and Labeau, Sonia (2017). Optimizing educational initiatives to prevent ventilator-associated complications. American Journal of Infection Control, 45 (1), 102-103. doi: 10.1016/j.ajic.2016.05.035

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries

International Surgical Outcomes Study group and Koulenti, Despoina (2016). Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. British Journal of Anaesthesia, 117 (5), 601-609. doi: 10.1093/bja/aew316

Factors influencing outcomes in intensive care unit patients with nosocomial infections

Blot, Stijn and Koulenti, Despoina (2016). Factors influencing outcomes in intensive care unit patients with nosocomial infections. Archives of Iranian Medicine, 19 (9), 677-678.

The value of polyurethane-cuffed endotracheal tubes to reduce microaspiration and intubation-related pneumonia: a systematic review of laboratory and clinical studies

Blot, Stijn I., Rello, Jordi and Koulenti, Despoina (2016). The value of polyurethane-cuffed endotracheal tubes to reduce microaspiration and intubation-related pneumonia: a systematic review of laboratory and clinical studies. Critical Care, 20 (1) 203, 203. doi: 10.1186/s13054-016-1380-8

Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study

Koulenti, D., Tsigou, E. and Rello, J. (2016). Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study. European Journal of Clinical Microbiology and Infectious Diseases, 36 (11), 1-8. doi: 10.1007/s10096-016-2703-z

Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study

Paiva, Jose-Artur, Pereira, Jose Manuel, Tabah, Alexis, Mikstacki, Adam, de Carvalho, Frederico Bruzzi, Koulenti, Despoina, Ruckly, Stephane, Cakar, Nahit, Misset, Benoit, Dimopoulos, George, Antonelli, Massimo, Rello, Jordi, Ma, Xiaochun, Tamowicz, Barbara and Timsit, Jean-Francois (2016). Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study. Critical Care, 20 (1) 53, 53. doi: 10.1186/s13054-016-1229-1

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

COPD patients with ventilator-associated pneumonia: implications for management

Koulenti, D., Blot, S., Dulhunty, J.M., Papazian, L., Martin-Loeches, I., Dimopoulos G., Brun-Buisson C., Nauwynck M., Putensen C., Sole-Violan J., Armaganidis A., Rello J. and The Eu-Vap/Cap Study Group (2015). COPD patients with ventilator-associated pneumonia: implications for management. European Journal of Clinical Microbiology and Infectious Diseases, 34 (12), 2403-2411. doi: 10.1007/s10096-015-2495-6

The surviving sepsis campaign bundles and outcome: results from the international multicentre prevalence study on sepsis (the IMPreSS study)

Rhodes, Andrew, Phillips, Gary, Beale, Richard, Cecconi, Maurizio, Chiche, Jean Daniel, de Backer, Daniel, Divatia, Jigeeshu, Du, Bin, Evans, Laura, Ferrer, Ricard, Girardis, Massimo, Koulenti, Despoina, Machado, Flavia, Simpson, Steven Q., Tan, Cheng Cheng, Wittebole, Xavier and Levy, Mitchell (2015). The surviving sepsis campaign bundles and outcome: results from the international multicentre prevalence study on sepsis (the IMPreSS study). Intensive Care Medicine, 41 (9), 1620-1628. doi: 10.1007/s00134-015-3906-y

Angiopoietin-2 associations with the underlying infection and sepsis severity

Lymperopoulou, Korina, Velissaris, Dimitrios, Kostaki, Antigone, Antypa, Elli, Georgiadou, Sara, Tsanganos, Thomas, Koulenti, Despoina , Paggalou, Evgenia, Damoraki, Georgia, Karagiannidis, Napoleon and Orfanos, Stylianos E. (2015). Angiopoietin-2 associations with the underlying infection and sepsis severity. Cytokine, 73 (1), 163-168. doi: 10.1016/j.cyto.2015.01.022

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015). Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 (5), 969-969. doi: 10.1007/s00134-015-3772-7

Bloodstream infections in ICU with increased resistance: epidemiology and outcomes

Dimopoulos, G., Koulenti, D., Tabah, A., Poulakou, G., Vesin, A., Arvaniti, K., Lathyris, D., Matthaiou, D. K., Armaganidis, A. and Timsit, J. F. (2015). Bloodstream infections in ICU with increased resistance: epidemiology and outcomes. Minerva Anestesiologica, 81 (4), 405-418.

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3

Point prevalence of surgical checklist use in Europe: Relationship with hospital mortality

Jammer, I, Ahmad, T, Aldecoa, C, Koulenti, D, Goranovic, T, Grigoras, I, Mazul-Sunko, B, Matos, R, Moreno, R, Sigurdsson, G. H, Toft, P, Walder, B, Rhodes, A and Pearse, R. M (2015). Point prevalence of surgical checklist use in Europe: Relationship with hospital mortality. British Journal of Anaesthesia, 114 (5), 801-807. doi: 10.1093/bja/aeu460

World alliance against antibiotic resistance: The WAAAR declaration against antibiotic resistance

Carlet, Jean, Aaron, Laurent, Abassi, Mohamed Salah, Abbo, Lilian, Aboderin, Oladipo, Abraham, Edward, Abroug, Fekri, Acar, Jacques, Achour, Wafa, Adachi, Javier, Al-Abri, Seif, Al-Mousa, Haifaa, Albaya-Moreno, Antonio, Alberti, Corinne, Alfandari, Serge, Alnimr, Amani, Aranda, Celia Alpuche, de Lerma, Francisco Alvarez, Amer, Fatma, Andremont, Antoine, Angoulvant, François, Anguill, Maryvonne, Antonelli, Massimo, Antoniadou, Eleni, Arlet, Guillaume, Armaganidis, Apostolos, Arnera, Anne, Artigas, Antonio, Attali, Claude ... Zubareva, Nadezhda (2015). World alliance against antibiotic resistance: The WAAAR declaration against antibiotic resistance. Medicina Intensiva, 39 (1), 34-39. doi: 10.1016/j.medin.2014.10.004

Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels

Hanberger, Hakan, Antonelli, Massimo, Holmbom, Martin, Lipman, Jeffrey, Pickkers, Peter, Leone, Marc, Rello, Jordi, Sakr, Yasser, Walther, Sten M., Vanhems, Philippe, Vincent, Jean-Louis, for the EPIC II Group of Investigators and Koulenti, D. (2014). Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels. BMC Infectious Diseases, 14 (513) 513. doi: 10.1186/1471-2334-14-513

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403

Respiratory infections in patients undergoing mechanical ventilation

Rello, Jordi, Lisboa, Thiago and Koulenti, Despoina (2014). Respiratory infections in patients undergoing mechanical ventilation. The Lancet Respiratory Medicine, 2 (9), 764-774. doi: 10.1016/S2213-2600(14)70171-7

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014). Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 (3) R99, 1-11. doi: 10.1186/cc13874

What's new in invasive pulmonary aspergillosis in the critically ill

Koulenti, Despoina, Vogelaers, Dirk and Blot, Stijn (2014). What's new in invasive pulmonary aspergillosis in the critically ill. Intensive Care Medicine, 40 (5), 723-726. doi: 10.1007/s00134-014-3254-3

DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 (8), 1072-1083. doi: 10.1093/cid/ciu027

Approach to invasive pulmonary aspergillosis in critically ill patients

Koulenti, Despoina, Garnacho-Montero, Jose and Blot, Stijn (2014). Approach to invasive pulmonary aspergillosis in critically ill patients. Current Opinion in Infectious Diseases, 27 (2), 174-183. doi: 10.1097/QCO.0000000000000043

Persistence of colonisation with MDRO following discharge from the ICU

Lucet, Jean-Christophe, Koulenti, Despoina and Zahar, Jean-Ralph (2014). Persistence of colonisation with MDRO following discharge from the ICU. Intensive Care Medicine, 40 (4), 603-605. doi: 10.1007/s00134-014-3258-z

Something Behind "Age" Reply

Blot, Stijn, Koulenti, Despoina and Rello, Jordi (2014). Something Behind "Age" Reply. Critical Care Medicine, 42 (4), E314-E315. doi: 10.1097/CCM.0000000000000179

Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients

Blot, Stijn, Koulenti, Despoina, Dimopoulos, George, Martin, Claude, Komnos, Apostolos, Krueger, Wolfgang A., Spina, Giuseppe, Armaganidis, Apostolos and Rello, Jordi (2014). Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients. Critical Care Medicine, 42 (3), 601-609. doi: 10.1097/01.ccm.0000435665.07446.50

Critically ill elderly adults with infection: analysis of the extended prevalence of infection in intensive care study

Dimopoulos, George , Koulenti, Despoina , Blot, Stijn, Sakr, Yasser, Anzueto, Antonio , Spies, Claudia , Violan, Jordi Solé, Kett, Daniel , Armaganidis, Apostolos , Martin, Claude , Vincent, Jean Louis and Extended Prevalence of Infection in Intensive Care Study Investigators (2014). Critically ill elderly adults with infection: analysis of the extended prevalence of infection in intensive care study. Journal of American Geriatric Society, 61 (12), 2065-2071. doi: 10.1111/jgs.12544

Erratum: Critically ill elderly adults with infection: analysis of the extended prevalence of infection in intensive care study

Dimopoulos, G., Koulenti, D. and Blot, S. (2014). Erratum: Critically ill elderly adults with infection: analysis of the extended prevalence of infection in intensive care study. Journal of the American Geriatrics Society, 62 (4). doi: 10.1111/jgs.12873

Hospital mortality of adults admitted to intensive care units in hospitals with and without intermediate care units: A multicentre European cohort study

Capuzzo, Maurizia, Volta, Carlo Alberto, Tassinati, Tania, Moreno, Rui Paulo, Valentin, Andreas, Guidet, Bertrand, Iapichino, Gaetano, Martin, Claude, Perneger, Thomas, Combescure, Christophe, Poncet, Antoine, Oeyen, Sandra, Rhodes, Andrew, on behalf of the Working Group on Health Economics of the European Society of Intensive Care Medicine, Matejovic, Martin, Toft, Palle, Wrigge, Hermann, Koulenti, Despoina, Breen, Dorothy, Melotti, Rita Maria, Strand, Kristian, Tamowicz, Barbara, Matos, Ricardo, Hagau, Natalia, Navarro, Pedro Navarrete, Dikmen, Yalim and Cecconi, Maurizio (2014). Hospital mortality of adults admitted to intensive care units in hospitals with and without intermediate care units: A multicentre European cohort study. Critical Care, 18 (5) 18. doi: 10.1186/s13054-014-0551-8

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014). Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 (9), 1340-1351. doi: 10.1007/s00134-014-3403-8

Update in hospital-acquired bacteremia respiratory infections: experience from the EUROBACT study

Timsit, Jean-Francois, Tabah, Alexis, Koulenti, Despoina, Ruckly, Stephane, Laupland, Kevin B., Garrouste-Orgeas, Maite, Zahar, Jean-Ralph, Blot, Sjin, De Carvalho, Frederico Bruzzi, Paiva, Jose A. and Dimopoulos, George (2014). Update in hospital-acquired bacteremia respiratory infections: experience from the EUROBACT study. Clinical Pulmonary Medicine, 21 (1), 9-15. doi: 10.1097/CPM.0000000000000014

Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study

Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014). Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 (5), 423-430. doi: 10.1016/j.ijantimicag.2014.01.023

Diagnosis and management of temperature abnormality in ICUs: A EUROBACT investigators' survey

Niven, Daniel J, Laupland, Kevin B, Tabah, Alexis, Vesin, Aurélien, Rello, Jordi, Koulenti, Despoina, Dimopoulos, George, de Waele, Jan and Timsit, Jean-Francois (2013). Diagnosis and management of temperature abnormality in ICUs: A EUROBACT investigators' survey. Critical Care, 17 (6) R289, R289.1-R289.8. doi: 10.1186/cc13153

What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013). What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 (4), 289-293. doi: 10.1016/j.ijantimicag.2013.05.018

Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors

Martin-Loeches, Ignacio, Deja, Maria, Koulenti, Despoina, Dimopolous, George, Marsh, Brian, Torres, Antonio, Niederman, Michael S., Rello, Jordi and EU-VAP Study Investigators (2013). Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors. Intensive Care Medicine, 39 (4), 672-681. doi: 10.1007/s00134-012-2808-5

Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study

Tabah, Alexis, Koulenti, Despoina, Laupland, Kevin, Misset, Benoit, Valles, Jordi, de Carvalho, Frederico Bruzzi, Paiva, Jose Artur, Cakar, Nahit, Ma, Xiaochun, Eggimann, Philippe, Antonelli, Massimo, Bonten, Marc J. M., Csomos, Akos, Krueger, Wolfgang A., Mikstacki, Adam, Lipman, Jeffrey, Depuydt, Pieter, Vesin, Aurelien, Garrouste-Orgeas, Maite, Zahar, Jean-Ralph, Blot, Stijn, Carlet, Jean, Brun-Buisson, Christian, Martin, Claude, Rello, Jordi, Dimopoulos, Georges, Timsit, Jean-Francois and EUROBACT Study Group (2012). Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Medicine, 38 (12), 1930-1945. doi: 10.1007/s00134-012-2695-9

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012). DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 (1) 152, 152.1-152.7. doi: 10.1186/1471-2334-12-152

Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia

Rello, J., Ulldemolins, M., Lisboa, T., Koulenti, D., Manez, R., Martin-Loeches, I., De Waele, J. J., Putensen, C., Guven, M., Deja, M., Diaz, E. and EU-VAP/CAP Study Group (2011). Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia. The European Respiratory Journal, 37 (6), 1332-1339. doi: 10.1183/09031936.00093010

Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study

Magret, Mònica, Lisboa, Thiago, Martin-Loeches, Ignacio, Manez, Rafael, Nauwynck, Marc, Wrigge, Hermann, Cardellino, Silvano, Diaz, Emili, Koulenti, Despina, Rello, Jordi and EU-VAP/CAP Study Group (2011). Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study. Critical Care, 15 (1) R62. doi: 10.1186/cc10036

Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection

Martin-Loeches, Ignacio, Lisboa, Thiago, Rhodes, Andrew, Moreno, R. P., Silva, Eliezer, Sprung, C., Chiche, Jean-Daniel, Barahona, Diego, Villabon, Mario, Balasini, Carina, Pearse, Rupert, Matos, Ricardo, Rello, Jordi, Rodriguez, Alejandro, Capuzzo, Maurizia, Reina, Rosa, Marsh, Brian, Flaaten, Haans, Sigurdsson, Gisli, Ivana, Zykova, Cerny, Vladimir, Quintel, Michael, Welte, Tobias, Mayorga, Manuel, Offenstadt, Georges, Guidet, Bertrand, Levin, Phillip, Rothen, Hans-Ulrich, Gomersall, Charles ... The ESICM H1N1 Registry Contributors (2011). Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection. Intensive Care Medicine, 37 (2), 272-283. doi: 10.1007/s00134-010-2078-z

Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients

Blot, Stijn I., Serra, Mireia Llaurado, Koulenti, Despoina, Lisboa, Thiago, Deja, Maria, Myrianthefs, Pavlos, Manno, Emilpaolo, Diaz, Emili, Topeli, Arzu, Martin-Loeches, Ignacio and Rello, Jordi (2011). Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients. American Journal of Critical Care, 20 (1), e1-e9. doi: 10.4037/ajcc2011555

Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units

Koulenti, Despoina, Lisboa, Thiago, Brun-Buisson, Christian, Krueger, Wolfgang, Macor, Antonio, Sole-Violan, Jordi, Diaz, Emili, Topeli, Arzu, DeWaele, Jan, Carneiro, Antonio, Martin-Loeches, Ignacio, Armaginidis, Apostolos, Rello, Jordi and EU-VAP/CAP Study (2009). Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units. Critical Care Medicine, 37 (8), 2360-2368. doi: 10.1097/CCM.0b013e3181a037ac.

Quality of life outcome of critical care survivors eighteen months after discharge from intensive care

Fildissis, George, Zidianakis, Vasilios, Tisgou, Efi, Koulenti, Despina, Katostaras, Theofanis , Economou, Aikaterini and Baltopoulos, George (2007). Quality of life outcome of critical care survivors eighteen months after discharge from intensive care. Croatian Medical Journal, 48 (6), 814-821. doi: 10.3325/cmj.2007.6.814

Oral care practices in intensive care units: a survey of 59 European ICUs

Rello, Jordi, Koulenti, Despoina, Blot, Stijn, Sierra, Rafael, Diaz, Emili, De Waele, Jan J., Macor, Antonio, Agbaht, Kemal and Rodriguez, Alejandro (2007). Oral care practices in intensive care units: a survey of 59 European ICUs. Intensive Care Medicine, 33 (6), 1066-1070. doi: 10.1007/s00134-007-0605-3

Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care

Koulenti, Despoina and Rello, Jordi (2006). Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care. Expert Opinion in Pharmacotherapy, 7 (12), 1555-1569. doi: 10.1517/14656566.7.12.1555

Gram-negative bacterial pneumonia: aetiology and management

Koulenti, Despoina and Rello, Jordi (2006). Gram-negative bacterial pneumonia: aetiology and management. Current Opinion in Pulmonary Medicine, 12 (3), 198-204. doi: 10.1097/01.mcp.0000219269.73180.5d

Desmoid tumor presenting as intra-abdominal abscess

Cholongitas, E., Despoina, K., Panetsos, G., Kafiri, G., Tzirakis, E., Thalasinou, P. and Papatheodoridis, G. V. (2006). Desmoid tumor presenting as intra-abdominal abscess. Digestive Diseases and Sciences, 51 (1), 68-69. doi: 10.1007/s10620-006-3086-2

Neumonía nosocomial causada por Staphylococcus aureus resistente a meticilina [Hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus]

Koulenti, Despoina (2005). Neumonía nosocomial causada por Staphylococcus aureus resistente a meticilina [Hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus]. Enfermedades Infecciosas y Microbiología Clínica, 23 (Supplement 3), 37-45. doi: 10.1157/13091219

Nimesulide-induced acute hepatitis

Cholongitas, E., Koulenti, D., Petraki, K. and Papatheodoridis, George V. (2003). Nimesulide-induced acute hepatitis. Annals of Gastroenterology, 16 (4), 359-362.

Intraabdominal abscess formation as a first presentation of desmoid tumor

Koulenti, D., Panetsos, G., Cholongitas, E., Kafiri, G., Tzirakis, G., Thalasinou, P. and Papatheodoridis, G. V. (2003). Intraabdominal abscess formation as a first presentation of desmoid tumor. Archives of Hellenic Medicine, 20 (3), 308-311.

Hospital-Acquired Bloodstream Infections in Greek Icus: Results From the Eurobact Study

Dimopoulos, George, Koulenti, Despoina, Tabah, Alexis, Arvaniti, Kostoula, Poulakou, Garyphalia, Matthaiou, Dimitrios, Armaganidis, Apostolos and Timsit, Jean Francois (2012). Hospital-Acquired Bloodstream Infections in Greek Icus: Results From the Eurobact Study. 42nd Critical Care Congress of the Society-of-Critical-Care-Medicine, San Juan Pr, Jan 19-23, 2013. LIPPINCOTT WILLIAMS & WILKINS.

CHARACTERISTICS OF HOSPITAL-ACQUIRED BLOODSTREAM INFECTIONS IN INTENSIVE CARE UNITS: THE EUROBACT STUDY

Tabah, A., Koulenti, D., Blot, S., Misset, B., Bruzzi de Carvalho, F., Cakar, N., Mikstacki, A., Laupland, K., Rello, J., Martin, C., Zahar, J. -R and Timsit, J. -F (2011). CHARACTERISTICS OF HOSPITAL-ACQUIRED BLOODSTREAM INFECTIONS IN INTENSIVE CARE UNITS: THE EUROBACT STUDY. NEW YORK: SPRINGER.

Center- and Patient-Based Determinants of Day28 Mortality of Hospital-Acquired Bloodstream Infections in Intensive Care Units: the Eurobact Study

Timsit, J. -F., Laupland, K., Koulenti, D., Antonelli, M., Xiaochun, M., Vesin, A., Bonten, M., Brun-Buisson, C., Eggimann, P., Krueger, W., Garrouste-Orgcas, M., Valles, J., Carlet, J., Paiva, J. -A., Tabah, A. and Dimopoulos, G. (2011). Center- and Patient-Based Determinants of Day28 Mortality of Hospital-Acquired Bloodstream Infections in Intensive Care Units: the Eurobact Study. SPRINGER.

Characteristics of liver dysfunction in critically ill patients

Koulenti, D., Mis, M., Myrianthefs, P., Tsigou, E., Ioannidis, C., Gavala, A., Grigoriou, P. and Baltopoulos, G. (2004). Characteristics of liver dysfunction in critically ill patients. 17th ESICM Annual Congress, Berlin, Germany, 10-13 October 2004. Heidelberg, Germany: Springer.

Outcome of ICU patients compared to admission status

Myrianthefs, P., Tsigou, E., Koulenti, D., Zidianakis, V., Fildisis, G. and Baltopoulos, G. (2004). Outcome of ICU patients compared to admission status. 17th Annual Congress of the European Society of Intensive Care Medicine, Berlin, Germany, 10-13 October 2004. Springer.