A/Prof Barbara Rolfe is a Group Leader at the Australian Institute for Bioengineering and Nanotechnology. A/Prof Rolfe is an immunologist and cell biologist, whose major research interests are the role of the innate immune system in cancer, the identification of novel therapeutic strategies for cancer, and nanomaterial safety. Her research has led to the identification of a previously unknown mechanism by which dysregulation of the immune system contributes to cancer development and growth, and provided information regarding the immune response to nanomaterials and the influence of physicochemical characteristics on biodistribution and cellular uptake. A/Prof Rolfe has used mouse models and small peptide agonists and antagonists to investigate the role of the innate immune system in tumour development and growth. This research demonstrated for the first time an important role for complement proteins in promoting tumour growth via regulation of immunosuppressive innate immune cells. Ongoing research is aimed focussed on gaining a better understanding of the role of complement proteins in tumour growth, developing novel immunotherapeutic strategies for cancer and investigating the application of nanomaterials for targeted delivery of anti-cancer drugs.
Journal Article: Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
Ortiz-Espinosa, Sergio, Morales, Xabier, Senent, Yaiza, Alignani, Diego, Tavira, Beatriz, Macaya, Irati, Ruiz, Borja, Moreno, Haritz, Remírez, Ana, Sainz, Cristina, Rodriguez-Pena, Alejandro, Oyarbide, Alvaro, Ariz, Mikel, Andueza, Maria P., Valencia, Karmele, Teijeira, Alvaro, Hoehlig, Kai, Vater, Axel, Rolfe, Barbara, Woodruff, Trent M., Lopez-Picazo, Jose Maria, Vicent, Silvestre, Kochan, Grazyna, Escors, David, Gil-Bazo, Ignacio, Perez-Gracia, Jose Luis, Montuenga, Luis M., Lambris, John D., Ortiz de Solorzano, Carlos ... Pio, Ruben (2022). Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis. Cancer Letters, 529, 70-84. doi: 10.1016/j.canlet.2021.12.027
Conference Publication: Immunoregulatory role for complement receptors in murine breast cancer
Rolfe, Barbara, Sonderegger, Stefan, McGirr, Crystal and Woodruff, Trent (2022). Immunoregulatory role for complement receptors in murine breast cancer. 28th Virtual International Complement Workshop (ICW) of the International-Complement-Society (ICS), Virtual, 6-10 December 2021. Oxford, United Kingdom: Elsevier.
Journal Article: Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity
Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174
ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals
(2023–2028) ARC Industrial Transformation Research Hubs
(2022) Exopharm
Complement C5aR1: A novel therapeutic target for brain cancer
(2021–2023) Brain Cancer Innovation Project Grants
Targeting hypoxic cancer stem cells with nanoparticles
(2021) Doctor Philosophy
Harnessing the Innate Immune System to Target Cancer: A Novel Immunotherapeutic Strategy for Solid Tumors
Doctor Philosophy
Contribution of complement anaphylatoxin receptors to melanoma growth: potential therapeutic targets
(2016) Doctor Philosophy
Gu, Z., Rolfe, Barbara E., Thomas, A. C., Campbell, Julie H., Lu, G. Q. Max and Xu, Z. P. (2012). Heparin-related nanomaterials. Heparin, properties, uses and side effects. (pp. 159-178) edited by David E. Piyathilake and Rhong Liang. New York, United States: Nova Science.
The fibrotic response to implanted biomaterials: Implications for tissue engineering
Rolfe, Barbara, Mooney, Jane, Zhang, Bing, Jahnke, Sani, Le, Sarah-Jane, Chau, Yu-Qian, Huang, Qiping, Wang, Hao, Campbell, Gordon and Campbell, Julie (2011). The fibrotic response to implanted biomaterials: Implications for tissue engineering. Regenerative Medicine and Tissue Engineering: Cells and Biomaterials. (pp. 551-568) edited by Daniel Eberli. Rijeka, Croatia: InTech Publishing.
Ortiz-Espinosa, Sergio, Morales, Xabier, Senent, Yaiza, Alignani, Diego, Tavira, Beatriz, Macaya, Irati, Ruiz, Borja, Moreno, Haritz, Remírez, Ana, Sainz, Cristina, Rodriguez-Pena, Alejandro, Oyarbide, Alvaro, Ariz, Mikel, Andueza, Maria P., Valencia, Karmele, Teijeira, Alvaro, Hoehlig, Kai, Vater, Axel, Rolfe, Barbara, Woodruff, Trent M., Lopez-Picazo, Jose Maria, Vicent, Silvestre, Kochan, Grazyna, Escors, David, Gil-Bazo, Ignacio, Perez-Gracia, Jose Luis, Montuenga, Luis M., Lambris, John D., Ortiz de Solorzano, Carlos ... Pio, Ruben (2022). Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis. Cancer Letters, 529, 70-84. doi: 10.1016/j.canlet.2021.12.027
Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity
Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174
An immunoregulatory role for complement receptors in murine models of breast cancer
Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002
Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Wang, Wenqian, Ta, Hang Thu, Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E., Gooding, J. Justin, Gaus, Katharina and Whittaker, Andrew K. (2020). Correction to High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging. ACS Nano, 14 (10), 14245-14246. doi: 10.1021/acsnano.0c07373
Editorial: The Role of Complement in Tumors
Rolfe, Barbara E., Pio, Ruben, Woodruff, Trent M., Markiewski, Maciej M. and Manthey, Helga D. (2020). Editorial: The Role of Complement in Tumors. Frontiers in Immunology, 11 139, 139. doi: 10.3389/fimmu.2020.00139
C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma
Nabizadeh, Jamileh A., Manthey, Helga D., Panagides, Nadya, Steyn, Frederik J., Lee, John D., Li, Xaria X., Akhir, Fazrena N. M., Chen, Weiyu, Boyle, Glen M., Taylor, Stephen M., Woodruff, Trent M. and Rolfe, Barbara E. (2019). C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma. FASEB Journal, 33 (10), fj201800980RR-11071. doi: 10.1096/fj.201800980rr
Chen, Weiyu, Zuo, Huali, Rolfe, Barbara, Schembri, Mark A., Cobbold, Rowland N., Zhang, Bing, Mahony, Timothy J. and Xu, Zhi Ping (2018). Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli. Journal of Controlled Release, 292, 196-209. doi: 10.1016/j.jconrel.2018.11.008
Yan, Shiyu, Xu, Kewei, Li, Li, Gu, Wenyi, Rolfe, Barbara E. and Xu, Zhi P. (2018). The pathways for layered double hydroxide nanoparticles to enhance antigen (cross)-presentation on immune cells as adjuvants for protein vaccines. Frontiers in Pharmacology, 9 (SEP) 1060, 1060. doi: 10.3389/fphar.2018.01060
Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles
Chen, Liyu, Glass, Joshua J., De Rose, Robert, Sperling, Claudia, Kent, Stephen J., Houston, Zachary H., Fletcher, Nicholas L., Rolfe, Barbara E. and Thurecht, Kristofer J. (2018). Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles. ACS Applied Bio Materials, 1 (3) acsabm.8b00220, 756-767. doi: 10.1021/acsabm.8b00220
Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Wang, Wenqian, Ta, Hang Thu, Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E., Gooding, John Justin, Gaus, Katharina and Whittaker, Andrew Keith (2018). High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging. ACS Nano, 12 (9) acsnano.8b03726, 9162-9176. doi: 10.1021/acsnano.8b03726
Chen, Weiyu, Zuo, Huali, Li, Bei, Duan, Chengcheng, Rolfe, Barbara, Zhang, Bing, Mahony, Timothy J and Xu, Zhi Ping (2018). Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation. Small, 14 (19) 1704465, e1704465. doi: 10.1002/smll.201704465
Fanning, Jonathon P., See Hoe, Louise E., Passmore, Margaret R., Barnett, Adrian G., Rolfe, Barbara E., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky and Fraser, John F. (2018). Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction. Therapeutic Advances in Neurological Disorders, 11, 1756286418759493. doi: 10.1177/1756286418759493
Yan, Shiyu, Gu, Wenyi, Zhang, Bing, Rolfe, Barbara E and Xu, Zhi Ping (2017). High adjuvant activity of layered double hydroxide nanoparticles and nanosheets in anti-tumour vaccine formulations. Dalton Transactions, 47 (9), 2956-2964. doi: 10.1039/c7dt03725b
Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611
Gu, Zi, Yan, Shiyu, Cheong, Soshan, Cao, Zhenbang, Zuo, Huali, Thomas, Anita C., Rolfe, Barbara E. and Xu, Zhi Ping (2017). Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system. Journal of Colloid and Interface Science, 512, 404-410. doi: 10.1016/j.jcis.2017.10.069
Chen, Weiyu, Zuo, Huali, Mahony, Timothy J, Zhang, Bing, Rolfe, Barbara and Xu, Zhi Ping (2017). Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge. Scientific reports, 7 (1) 13367, 1-12. doi: 10.1038/s41598-017-13570-2
Nabizadeh, Jamileh A., Manthey, Helga D., Steyn, Frederik J., Chen, Weiyu, Widiapradja, Alexander, Akhir, Fazrena N. Md, Boyle, Glen M., Taylor, Stephen M., Woodruff, Trent M. and Rolfe, Barbara E. (2016). The complement C3a receptor contributes to melanoma tumorigenesis by inhibiting neutrophil and CD4+ T cell responses. Journal of Immunology, 196 (11), 4783-4792. doi: 10.4049/jimmunol.1600210
Chen, Weiyu, Zhang, Bing, Mahony, Timothy, Gu, Wenyi, Rolfe, Barbara and Xu, Zhi Ping (2016). Efficient and durable vaccine against Intimin β of Diarrheagenic E. Coli induced by clay nanoparticles. Small, 12 (12), 1627-1639. doi: 10.1002/smll.201503359
Ma, Yiming, Fuchs, Adrian V., Boase, Nathan R. B., Rolfe, Barbara E., Coombes, Allan G. A. and Thurecht, Kristofer J. (2015). The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 393-403. doi: 10.1016/j.ejpb.2015.06.014
Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG
Yan, Shiyu, Rolfe, Barbara E., Zhang, Bing, Mohammed, Yousuf H., Gu, Wenyi and Xu, Zhi P. (2014). Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG. Biomaterials, 35 (35), 9508-9516. doi: 10.1016/j.biomaterials.2014.07.055
Development of a polymer theranostic for prostate cancer
Pearce, Amanda K., Rolfe, Barbara E., Russell, Pamela J., Tse, Brian W.-C., Whittaker, Andrew K., Fuchs, Adrian V. and Thurecht, Kristofer J. (2014). Development of a polymer theranostic for prostate cancer. Polymer Chemistry, 5 (24), 6932-6942. doi: 10.1039/C4PY00999A
Synthesis of a multimodal molecular imaging probe based on a hyperbranched polymer architecture
Boase, Nathan R. B., Blakey, Idriss, Rolfe, Barbara E., Mardon, Karine and Thurecht, Kristofer J. (2014). Synthesis of a multimodal molecular imaging probe based on a hyperbranched polymer architecture. Polymer Chemistry, 5 (15), 4450-4458. doi: 10.1039/c4py00513a
Transcriptional switching in macrophages associated with the peritoneal foreign body response
Mooney, Jane E., Summers, Kim M., Gongora, Milena, Grimmond, Sean M., Campbell, Julie H., Hume, David A. and Rolfe, Barbara E. (2014). Transcriptional switching in macrophages associated with the peritoneal foreign body response. Immunology and Cell Biology, 92 (6), 518-526. doi: 10.1038/icb.2014.19
Rolfe, Barbara E., Blakey, Idriss, Squires, Oliver, Peng, Hui, Boase, Nathan R. B., Alexander, Cameron, Parsons, Peter G., Boyle, Glen M., Whittaker, Andrew K. and Thurecht, Kristofer J. (2014). Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo. Journal of the American Chemical Society, 136 (6), 2413-2419. doi: 10.1021/ja410351h
Restenosis treatments using nanoparticle-based drug delivery systems
Gu, Zi, Rolfe, Barbara E., Thomas, Anita C. and Xu, Zhi Ping (2013). Restenosis treatments using nanoparticle-based drug delivery systems. Current Pharmaceutical Design, 19 (35), 6330-6339. doi: 10.2174/1381612811319350009
The in vivo and in vitro corrosion of high-purity magnesium and magnesium alloys WZ21 and AZ91
Abidin, Nor Ishida Zainal, Rolfe, Barbara, Owen, Helen, Malisano, Julian, Martin, Darren, Hofstetter, Joelle, Uggowitzer, Peter J. and Atrens, Andrej (2013). The in vivo and in vitro corrosion of high-purity magnesium and magnesium alloys WZ21 and AZ91. Corrosion Science, 75, 354-366. doi: 10.1016/j.corsci.2013.06.019
Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice
Matsumoto, Aya, Manthey, Helga D., Marsh, Susan A., Fassett, Robert G., de Haan, Judy B., Rolfe, Barbara E. and Coombes, Jeff S. (2013). Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice. International Journal of Cardiology, 167 (4), 1282-1288. doi: 10.1016/j.ijcard.2012.03.172
Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo
Coles, Daniel J., Rolfe, Barbara E., Boase, Nathan R. B., Veedu, Rakesh N. and Thurecht, Kristofer J. (2013). Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo. Chemical Communications, 49 (37), 3836-3838. doi: 10.1039/c3cc00127j
Antibody-targeted drug delivery to injured arteries using layered double hydroxide nanoparticles
Gu, Zi, Rolfe, Barbara E., Xu, Zhi Ping, Campbell, Julie H., Lu, G. Q. (Max) and Thomas, Anita C. (2012). Antibody-targeted drug delivery to injured arteries using layered double hydroxide nanoparticles. Advanced Healthcare Materials, 1 (5), 669-673. doi: 10.1002/adhm.201200069
Complement C5a: Impact on the field of veterinary medicine
Hezmee, M. N. M., Shiels, I. A., Rolfe, B. E. and Mills, P. C. (2012). Complement C5a: Impact on the field of veterinary medicine. The Veterinary Journal, 192 (3), 264-271. doi: 10.1016/j.tvjl.2011.12.008
Gu, Zi, Rolfe, Barbara E., Thomas, Anita C., Campbell, Julie H., Lu, G.Q. (Max) and Xu, Zhi P. (2011). Cellular trafficking of low molecular weight heparin incorporated in layered double hydroxide nanoparticles in rat vascular smooth muscle cells. Biomaterials, 32 (29), 7234-7240. doi: 10.1016/j.biomaterials.2011.05.083
Chau, Lien T., Rolfe, Barbara E. and Cooper-White, Justin J. (2011). A microdevice for the creation of patent, three-dimensional endothelial cell-based microcirculatory networks. Biomicrofluidics, 5 (3) 034115, Article number 034115-3411514. doi: 10.1063/1.3609264
Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice
Manthey, Helga D., Thomas, Anita C., Shiels, Ian A., Zernecke, Alma, Woodruff, Trent M., Rolfe, Barbara and Taylor, Stephen M. (2011). Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice. FASEB Journal, 25 (7), 2447-2455. doi: 10.1096/fj.10-174284
Zhu, Congli, Zhang, Liang, Zheng, Yong, Xu, Jing, Song, Jian, Rolfe, Barbara E. and Campbell, Julie H. (2011). Effects of estrogen on stress-induced premature senescence of vascular smooth muscle cells: A novel mechanism for the "time window theory" of menopausal hormone therapy. Atherosclerosis, 215 (2), 294-300. doi: 10.1016/j.atherosclerosis.2010.12.025
Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors
Hezmee, Mohd Noor Mohd, Kyaw-Tanner, Myat, Lee, Jia Yu Peppermint, Shiels, Ian A., Rolfe, Barbara, Woodruff, Trent and Mills, Paul C. (2011). Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors. Veterinary Immunology and Immunopathology, 139 (1), 50-56. doi: 10.1016/j.vetimm.2010.08.005
Gu, Zi, Rolfe, Barbara E., Xu, Zhi P., Thomas, Anita C., Campbell, Julie H. and Lu, Gao Q.M. (2010). Enhanced effects of low molecular weight heparin intercalated with layered double hydroxide nanoparticles on rat vascular smooth muscle cells. Biomaterials, 31 (20), 5455-5462. doi: 10.1016/j.biomaterials.2010.03.050
Gene expression profile of the fibrotic response in the peritoneal cavity
Le, S. J., Gongora, M., Zhang, B., Grimmond, S., Campbell, G. R., Campbell, J. H. and Rolfe, B. E. (2010). Gene expression profile of the fibrotic response in the peritoneal cavity. Differentiation, 79 (4-5), 232-243. doi: 10.1016/j.diff.2010.03.001
Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response
Mooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010). Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 (1), 369-380. doi: 10.2353/ajpath.2010.090545
Engineering tissue tubes using novel multilayered scaffolds in the rat peritoneal cavity
Cao, Yang, Zhang, Bing, Croll, Tristan, Rolfe, Barbara E., Campbell, Julie H., Campbell, Gordon R., Martin, Darren and Cooper-White, Justin J. (2008). Engineering tissue tubes using novel multilayered scaffolds in the rat peritoneal cavity. Journal of Biomedical Materials Research. Part A, 87A (3), 719-727. doi: 10.1002/jbm.a.31781
Campbell, Gordon R., Geoffrey Turnbull, Xiang, Lina, Haines, Michael, Shannon Armstrong, Rolfe, Barbara E. and Campbell, Julie H. (2008). The peritoneal cavity as a bioreactor for tissue engineering visceral organs: bladder, uterus and vas deferens. Journal of Tissue Engineering and Regenerative Medicine, 2 (1), 50-60. doi: 10.1002/term.66
Mechanics of cellular adhesion to artificial artery templates
Knoner, Gregor, Rolfe, Barbara E., Campbell, Julie H., Parkin, Simon J., Heckenberg, Norman R. and Rubinsztein-Dunlop, Halina (2006). Mechanics of cellular adhesion to artificial artery templates. Biophysical Journal, 91 (8), 3085-3096. doi: 10.1529/biophysj.105.076125
Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006). Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 (11), 7000-7007. doi: 10.4049/jimmunol.176.11.7000
Engineering tissue tubes using novel multilayered scaffolds in the rabbit and rat peritoneal cavity
Cao, Yang, Zhang, Bing, Croll, Tristan I., Rolfe, Barbara E., Campbell, Julie H., Campbell, Gordon R., Martin, Darren J. and Cooper-White, Justin J. (2006). Engineering tissue tubes using novel multilayered scaffolds in the rabbit and rat peritoneal cavity. Tissue Engineering, 12 (4), 1020-1021.
Cholestanol: A serum marker to guide LDL cholesterol-lowering therapy
Hoenig, Michel R., Rolfe, Barbara E. and Campbell, Julie H. (2006). Cholestanol: A serum marker to guide LDL cholesterol-lowering therapy. Atherosclerosis, 184 (2), 247-254. doi: 10.1016/j.atherosclerosis.2005.09.007
Growth factor regulation of myofibroblast differentiation
Rolfe, B. E., Zhang, B., Wigan, M. P., Pearson, K., Chen, Y., Pantarat, S., Campbell, J. H., Jahnke, S, Chau, Y. and Campbell, G. R. (2006). Growth factor regulation of myofibroblast differentiation. Cytometry Part A, 69A (5), 423-424.
Life and death in developing myofibroblast capsules
Le, S., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (2006). Life and death in developing myofibroblast capsules. Cytometry Part A, 69A (5), 419-419. doi: 10.1002/cyto.a.20264
Monocytes/macrophages and foreign body encapsulation in the peritoneal cavity
Mooney, J. E., Rolfe, B. E., Zhang, B., Sester, P., Campbell, J. H. and Campbell, G. R. (2006). Monocytes/macrophages and foreign body encapsulation in the peritoneal cavity. Cytometry Part A, 69A (5), 421-421.
Tissue-engineered blood vessels: Alternative to autologous grafts?
Hoenig, Michel R., Campbell, Gordon R., Rolfe, Barbara E. and Campbell, Julie H. (2005). Tissue-engineered blood vessels: Alternative to autologous grafts?. Arteriosclerosis, Thrombosis, and Vascular Biology, 25 (6), 1128-1134. doi: 10.1161/01.ATV.0000158996.03867.72
Rolfe, B. E., Worth, N. F., World, C. J., Campbell, J. H. and Campbell, G. R. (2005). Rho and vascular disease. Atherosclerosis, 183 (1), 1-16. doi: 10.1016/j.atherosclerosis.2005.04.023
Rho expression and activation in vascular smooth muscle cells
Worth, N. F., Campbell, G. R., Campbell, J. H. and Rolfe, B. E. (2004). Rho expression and activation in vascular smooth muscle cells. Cell Motility and the Cytoskeleton, 59 (3), 189-200. doi: 10.1002/cm.20036
THE THERAPEUTIC ACTIONS OF LIF ON THE VASCULATURE
World, Cameron, Rolfe, Barbara and Campbell, Julie (2004). THE THERAPEUTIC ACTIONS OF LIF ON THE VASCULATURE. Cardiovascular Pathology, 13 (3), 61. doi: 10.1016/j.carpath.2004.03.179
The effects of leukemia inhibitory factor (LIF) on neointimal formation in injured arteries
World, C.J., Merrilees, M.J., Beaumont, B., Campbell, G. R., Campbell, J. H. and Rolfe, B. E. (2004). The effects of leukemia inhibitory factor (LIF) on neointimal formation in injured arteries. Biomedical Research, 15 (2), 169-175.
Leukaemia inhibitory factor retards the progression of atherosclerosis
Rolfe, Barbara E., Stamatiou, Steve, World, Cameron J., Brown, Lindsay, Thomas, Anita C., Bingley, John A., Worth, Nathalie F. and Campbell, Julie H. (2003). Leukaemia inhibitory factor retards the progression of atherosclerosis. Cardiovascular Research, 58 (1), 222-230. doi: 10.1016/S0008-6363(02)00832-5
Rho and smooth muscle cell phenotype
Worth, N. F., Rolfe, B. E., Campbell, J. H. and Campbell, G. R. (2003). Rho and smooth muscle cell phenotype. International Congress Series, 1262 (C), 111-114. doi: 10.1016/S0531-5131(03)01863-6
Regulation of LIF receptor expression in vascular smooth muscle
World, C., Rolfe, B. E. and Campbell, J. H. (2001). Regulation of LIF receptor expression in vascular smooth muscle. Annals of the New York Academy of Sciences, 947 (1), 323-328. doi: 10.1111/j.1749-6632.2001.tb03956.x
Song, J., Rolfe, B. E., Hayward, I. P., Campbell, G. R. and Campbell, J. H. (2001). Reorganization of structural proteins in vascular smooth muscle cells grown in collagen gel and basement membrane matrices (Matrigel): A comparison with their in situ counterparts. Journal of Structural Biology, 133 (1), 43-54. doi: 10.1006/jsbi.2001.4327
Worth, N. F., Rolfe, B. E., Song, J. and Campbell, G. R. (2001). Vascular smooth muscle cell phenotypic modulation in culture is associated with reorganisation of contractile and cytoskeletal proteins. Cell Motility And The Cytoskeleton, 49 (3), 130-145. doi: 10.1002/cm.1027
ICAM-1expression by vascular smooth muscle cells is phenotype-dependent
Rolfe, B. E., Muddiman, J. D., Smith, N. J., Campbell, G. R. and Campbell, J. H. (2000). ICAM-1expression by vascular smooth muscle cells is phenotype-dependent. Atherosclerosis, 149 (1), 99-110. doi: 10.1016/S0021-9150(99)00322-6
Cuff-induced intimal thickening in the carotid artery of the marmoset
Badorrek, B., Rolfe, B. E., Campbell, J. H. and Campbell, G. R. (2000). Cuff-induced intimal thickening in the carotid artery of the marmoset. Biomedical Research, 11 (2), 179-188.
Do sub-populations of smooth muscle cells exist in the artery wall?
Thomas, A. C., Campbell, J. H., Rolfe, B. E. and Campbell, G. R. (2000). Do sub-populations of smooth muscle cells exist in the artery wall?. Journal of Molecular and Cellular Cardiology, 30, A40-A40.
Song, J., Rolfe, B. E., Hayward, I. P., Campbell, G. R. and Campbell, J. H. (2000). Effects of collagen gel configuration on behavior of vascular smooth muscle cells in vitro: association with vascular morphogenesis. In Vitro Cellular and Developmental Biology, 36 (9), 600-610. doi: 10.1290/1071-2690(2000)036
Song, J., Worth, N. F., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (2000). Heterogeneous distribution of isoactins in cultured vascular smooth muscle cells does not reflect segregation of contractile and cytoskeletal domains. Journal of Histochemistry & Cytochemistry, 48 (11), 1441-1452. doi: 10.1177/002215540004801101
Uzal, FA, Rolfe, BE, Smith, NJ, Thomas, AC and Kelly, WR (1999). Resistance of Ovine, Caprine and Bovine Endothelial Cells to Clostridium perfringens type D Epsilon Toxin In Vitro. Veterinary Research Communications, 23 (5), 275-284. doi: 10.1023/A:1006362819202
Song, J., Rolfe, B. E., Campbell, J. H. and Campbell, G. R. (1998). Changes in three-dimensional architecture of microfilaments in cultured vascular smooth muscle cells during phenotypic modulation. Tissue & Cell, 30 (3), 324-333. doi: 10.1016/S0040-8166(98)80045-1
Effect of estrogen on vascular smooth muscle cells is dependent upon cellular phenotype
Song, J., Wan, Y., Rolfe, B. E., Campbell, J. H. and Campbell, G. R. (1998). Effect of estrogen on vascular smooth muscle cells is dependent upon cellular phenotype. Atherosclerosis, 140 (1), 97-104. doi: 10.1016/S0021-9150(98)00122-1
T-Lymphocytes Affect Smooth-Muscle Cell Phenotype and Proliferation
Rolfe, B.E., Campbell, J.H., Smith, N.J., Cheong, M.W. and Campbell, G.R. (1995). T-Lymphocytes Affect Smooth-Muscle Cell Phenotype and Proliferation. Arteriosclerosis Thrombosis and Vascular Biology, 15 (8), 1204-1210. doi: 10.1161/01.ATV.15.8.1204
Rolfe, BE, Athanasasplatsis, S, Hoskin, MJ, Morton, H and Cavanagh, AC (1995). Purification and Partial Characterization of An Early-Pregnancy Factor-Induced Suppressor Factor (epf-S-1). American Journal of Reproductive Immunology, 33 (6), 485-494. doi: 10.1111/j.1600-0897.1995.tb00911.x
Athanasasplatsis, S, Hoskin, MJ, Rolfe, BE, Cavanagh, AC and Morton, H (1995). A Monoclonal-Antibody to An Early-Pregnancy Factor-Induced Suppressor Factor (epf-S-1) Disrupts Implantation in Mice. American Journal of Reproductive Immunology, 33 (3), 259-266. doi: 10.1111/j.1600-0897.1995.tb00893.x
Morton, H., Rolfe, B. E. and Cavanagh, A. C. (1992). Early-Pregnancy Factor. Seminars in Reproductive Endocrinology, 10 (2), 72-82. doi: 10.1055/s-2007-1018863
Early-Pregnancy Factor Has Immunosuppressive and Growth-Factor Properties
Morton, H, Cavanagh, AC, Athanasasplatsis, S, Quinn, KA and Rolfe, BE (1992). Early-Pregnancy Factor Has Immunosuppressive and Growth-Factor Properties. Reproduction Fertility and Development, 4 (4), 411-422. doi: 10.1071/RD9920411
Cavanagh, AC, Rolfe, BE, Athanasasplatsis, S, Quinn, KA and Morton, H (1991). Relationship Between Early-Pregnancy Factor, Mouse Embryo-Conditioned Medium and Platelet-Activating-Factor. Journal of Reproduction and Fertility, 93 (2), 355-365. doi: 10.1530/jrf.0.0930355
Identification of a Putative Inhibitor of Early-Pregnancy Factor in Mice
Cavanagh, AC, Morton, H, Athanasasplatsis, S, Quinn, KA and Rolfe, BE (1991). Identification of a Putative Inhibitor of Early-Pregnancy Factor in Mice. Journal of Reproduction and Fertility, 91 (1), 239-248. doi: 10.1530/jrf.0.0910239
Monoclonal-Antibodies to Early-Pregnancy Factor Perturb Tumor-Cell Growth
Quinn, KA, Athanasasplatsis, S, Wong, TY, Rolfe, BE, Cavanagh, AC and Morton, H (1990). Monoclonal-Antibodies to Early-Pregnancy Factor Perturb Tumor-Cell Growth. Clinical and Experimental Immunology, 80 (1), 100-108. doi: 10.1111/j.1365-2249.1990.tb06448.x
Athanasasplatsis, S, Quinn, KA, Wong, TY, Rolfe, BE, Cavanagh, AC and Morton, H (1989). Passive-Immunization of Pregnant Mice Against Early-Pregnancy Factor Causes Loss of Embryonic Viability. Journal of Reproduction and Fertility, 87 (2), 495-502. doi: 10.1530/jrf.0.0870495
Rolfe B., Quinn K., Athanasas S., Cavanagh A. and Morton H. (1989). Genetically-restricted effector molecules released by human lymphocytes in response to early pregnancy factor.. Immunology and cell biology, 67 (3), 205-208. doi: 10.1038/icb.1989.31
Identification of 2 Suppressor Factors Induced by Early-Pregnancy Factor
Rolfe, BE, Cavanagh, AC, Quinn, KA and Morton, H (1988). Identification of 2 Suppressor Factors Induced by Early-Pregnancy Factor. Clinical and Experimental Immunology, 73 (2), 219-225.
OVUM factor and early pregnancy factor
Morton, Halle, Rolfe, Barbara E. and Cavanagh, Alice C. (1987). OVUM factor and early pregnancy factor. Current Topics in Developmental Biology, 23 (C), 73-92. doi: 10.1016/S0070-2153(08)60620-1
Ovum Factor and Early-Pregnancy Factor
Morton, H, Rolfe, BE and Cavanagh, AC (1987). Ovum Factor and Early-Pregnancy Factor. Current Topics in Developmental Biology, 23, 73-92.
Rolfe, Barbara, Cavanagh, Alice, Forde, Caron, Bastin, Fern, Chen, Christopher and Morton, Halle (1984). Modified rosette inhibition test with mouse lymphocytes for detection of early pregnancy factor in human pregnancy serum. Journal of Immunological Methods, 70 (1), 1-11. doi: 10.1016/0022-1759(84)90383-1
Rolfe, BE, Morton, H, Cavanagh, AC and Gardiner, RA (1983). Detection of An Early-Pregnancy Factor-Like Substance in Sera of Patients with Testicular Germ-Cell Tumors. American Journal of Reproductive Immunology, 3 (2), 97-100. doi: 10.1111/j.1600-0897.1983.tb00223.x
Rolfe, BE, Morton, H and Clarke, FM (1983). Early-Pregnancy Factor Is An Immunosuppressive Contaminant of Commercial Preparations of Human Chorionic-Gonadotropin. Clinical and Experimental Immunology, 51 (1), 45-52.
Rolfe, BE (1982). Detection of Fetal Wastage. Fertility and Sterility, 37 (5), 655-660. doi: 10.1016/S0015-0282(16)46278-3
Ovum Factor - a 1st Signal of Pregnancy
Cavanagh, AC, Morton, H, Rolfe, BE and Gidleybaird, AA (1982). Ovum Factor - a 1st Signal of Pregnancy. American Journal of Reproductive Immunology, 2 (2), 97-101. doi: 10.1111/j.1600-0897.1982.tb00093.x
Rosette inhibition test: A multicentre investigation of early pregnancy factor in humans
Morton, Halle, Tinneberg, Hans-Rudolf, Rolfe, Barbara, Wolf, Marianne and Mettler, Lilo (1982). Rosette inhibition test: A multicentre investigation of early pregnancy factor in humans. Journal of Reproductive Immunology, 4 (5), 251-261. doi: 10.1016/0165-0378(82)90001-8
Early pregnancy factor: tissues involved in its production in the mouse
Morton, H., Rolfe, B. E., McNeill, L., Clarke, P., Clarke, F. M. and Clunie, G. J. A. (1980). Early pregnancy factor: tissues involved in its production in the mouse. Journal of Reproductive Immunology, 2 (2), 73-82. doi: 10.1016/0165-0378(80)90044-3
Partial Characterization of Early-Pregnancy Factor in the Sheep
Clarke, FM, Morton, H, Rolfe, BE and Clunie, Gja (1980). Partial Characterization of Early-Pregnancy Factor in the Sheep. Journal of Reproductive Immunology, 2 (3), 151-162. doi: 10.1016/0165-0378(80)90033-9
An early pregnancy factor detected in human serum by the Rosette Inhibition Test
Morton, Halle, Rolfe, Barbara, Clunie, Gordon J. A, Anderson, Margaret J. and Morrison, John (1977). An early pregnancy factor detected in human serum by the Rosette Inhibition Test. The Lancet, 309 (8008), 394-397. doi: 10.1016/S0140-6736(77)92605-8
Immunoregulatory role for complement receptors in murine breast cancer
Rolfe, Barbara, Sonderegger, Stefan, McGirr, Crystal and Woodruff, Trent (2022). Immunoregulatory role for complement receptors in murine breast cancer. 28th Virtual International Complement Workshop (ICW) of the International-Complement-Society (ICS), Virtual, 6-10 December 2021. Oxford, United Kingdom: Elsevier.
Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma
Nabizadeh, J., Manthey, H., Panagides, N., Steyn, F., Lee, J., Li, X., Woodruff, T. and Rolfe, B. (2019). Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October 2019. Weinheim, Germany: Wiley.
Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Ta, Hang T., Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E. and Whittaker, Andrew K. (2018). High F-Content Perfluoropolyether-based Polymers for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging. World Polymer Congress Macro 2018, Cairns QLD Australia, 1-5 July 2018.
Effect of hydrogels or lipoxinA4 on rat periodontal fibroblasts in-vitro
Varanasi, S., Wang, D., Peng, H., Do, H.L., Smid, J., Rolfe, B., Rasoul, F., Whittaker, A.K. and Symons, A. (2010). Effect of hydrogels or lipoxinA4 on rat periodontal fibroblasts in-vitro. Australian/New Zealand Division Golden Jubilee Meeting, Sebel Harbourside Hotel, Kiama, New South Wales, Australia,, September 27-29 2010.
Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis
Manthey, Helga, Thomas, Anita, Taylor, Stephen, Woodruff, Trent, Moore, Tyson, Shiels, Ian and Rolfe, Barbara (2008). Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September - 2 October 2008. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.molimm.2008.08.167
Does C5a have a role in the pathophysiology of atherosclerosis?
Manthey, H., Taylor, S., Shiels, I. and Rolfe, B. (2007). Does C5a have a role in the pathophysiology of atherosclerosis?. XXI International Complement Workshop, Beijing, China, 22-26 October 2006. Oxford, United Kingdom: Pergamon. doi: 10.1016/j.molimm.2006.07.154
Inhibition of myofibroblast differentiation by silencing transforming growth factor beta receptor
Chau, Yu-Qian, Zhang, Bing, Rolfe, Barbara, Wei, Ming and Campbell, Julie (2007). Inhibition of myofibroblast differentiation by silencing transforming growth factor beta receptor. Annual Congress of the European Society of Gene and Cell Therapy, De Doelen, Rotterdam, The Netherlands, 27-30 October, 2007. NEW ROCHELLE: MARY ANN LIEBERT INC.
Surface protein regulators of rat bone marrow-derived mesenchymal stem cell morphology
Clark, Sharon F., Cao, Yang, Croll, Tristan, Jahnke, Sani, Dyne, Al, Rolfe, Barbara, Brooke, Gary, Atkinson, Kerry, Campbell, Julie and Cooper-White, Justin (2007). Surface protein regulators of rat bone marrow-derived mesenchymal stem cell morphology. International Society for Stem Cell Research (ISSCR) Annual Meeting, Cairns, Qld, Australia, 17-20 June, 2007.
The peritoneal cavity as a bioreactor for tissue engineered arteries
Campbell, Julie H., Mooney, Jane, Le, Sarah, Walker, Philip, Zhang, Bing, Rolfe, Barbara and Campbell, Gordon R. (2006). The peritoneal cavity as a bioreactor for tissue engineered arteries. XIVth International Vascular Biology Meeting, Noordwijkerhout, Netherlands, 6-10 June 2006. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.vph.2006.08.128
Artifical arteries from cells of bone marrow origin
Campbell, J. H., Efendy, J., Chue, W., Daly, C., Mooney, J., Zhang, B., Rolfe, B., Walker, P. and Campbell, G. R. (2005). Artifical arteries from cells of bone marrow origin. Vascular 2005, Sydney, 9-14 Sep, 2005.
Rho and smooth muscle cell phenotype
Worth, N.F., Rolfe, B.E., Campbell, J.H. and Campbell, G.R. (2004). Rho and smooth muscle cell phenotype. Thirteenth International Symposium on Atherosclerosis, Kyoto, Japan, 27 September - 3 October 2003. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0531-5131(03)01863-6
Rho and smooth muscle cell phenotype
Worth, N. F., Rolfe, B. E. and Campbell, G. R. (2003). Rho and smooth muscle cell phenotype. 13th International Atherosclerosis Symposium, Kyoto, Japan, 28 September - 2 October 2004. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/S1567-5688(03)90774-4
A role for Rho in smooth muscle phenotypic regulation
Worth, N. F., Campbell, G. R. and Rolfe, B. E. (2001). A role for Rho in smooth muscle phenotypic regulation. 6th Saratoga International Conference on Atherosclerosis, Tokyo, Japan, 3-6 April 2001. Malden, MA United States: Wiley-Blackwell. doi: 10.1111/j.1749-6632.2001.tb03955.x
A role for Rho in smooth muscle phenotypic regulation
Campbell, G. R., Worth, N. F. and Rolfe, B. E. (2001). A role for Rho in smooth muscle phenotypic regulation. Australian Vascular Biology Society, Noosa, Queensland, Australia, Ausgust, 2001. New York: The Academy.
World, C., Rolfe, B. E. and Campbell, J. H. (2001). Attenuation of smooth muscle proliferation by leukaemia inhibitory factor involves the activation of negative feed-back regulators. COMBIO, Canberra, October 2001.
Rho as a regulator of smooth muscle phenotype
Rolfe, B. E., Worth, N.F. and Campbell, G. R. (2001). Rho as a regulator of smooth muscle phenotype. COMBIO, Canberra, October 2001.
Smooth muscle, the cytoskeleton and cell signalling
Worth, N.F., Rolfe, B. E. and Campbell, G. R. (2001). Smooth muscle, the cytoskeleton and cell signalling. Australian Vascular Biology Society 9th Scientific Annual Meeting, Noosa, Qld, 30 August - 2 September 2001.
World, C., Rolfe, B. E. and Campbell, J. H. (2001). The signal attenuating effects of LIF treated vascular smooth muscle cells as a means of inhibiting hyperplasia. Australian Vascular Biology Society 9th Annual Scientific Meeting, Noosa Qld, 30 August - September 2, 2001.
A role for Rho in smooth muscle phenotypic regulation
Worth, N., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (2000). A role for Rho in smooth muscle phenotypic regulation. International Congress on Differentiation & Cell Biology, Gold Coast, Australia, 24-28 September 2000. Australia: Magic Touch Pty Ltd.
Expression of LIF receptor subunits by cells of the artery wall
World, C., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (2000). Expression of LIF receptor subunits by cells of the artery wall. The Australian Vascular Biology Society 2000 Annual Scientific Meeting, Marysville, Victoria, 19-22 October 2000. Melbourne: Australian Vascular Biology Society.
Rho and vascular smooth muscle cell phenotype
Worth, N., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (2000). Rho and vascular smooth muscle cell phenotype. Xth International Vascular Biology Meeting, Geneva Switzerland, 5-9 September 2000. Siena, Italy: Nova Immagine Editrice - Siena.
The role of leukemia inhibitory factor in vascular smooth muscle cell function
World, C., Rolfe, B. E. and Campbell, J. H. (2000). The role of leukemia inhibitory factor in vascular smooth muscle cell function. International Congress on Differentiation & Cell Biology, Gold Coast, Australia, 24-28 September 2000. Australia: Magic Touch Pty Ltd.
Behaviour of rabbit aortic smooth muscle cells grown in three-dimensional collagen gel
Song, J., Rolfe, B. E., Hayward, I. P., Campbell, G. R. and Campbell, J. H. (1999). Behaviour of rabbit aortic smooth muscle cells grown in three-dimensional collagen gel. Combio99 Symposium, Gold Coast, 27-30 Sept 1999. Kent Town SA: Aust. Society for Biochemistry and Molecular Biology ..
Modified vascular smooth muscle cell behaviour in vitro by extracellular matrix
Song, J., Rolfe, B. E., Worth, N., Campbell, J. H., Campbell, G. R. and Hayward, I. P. (1999). Modified vascular smooth muscle cell behaviour in vitro by extracellular matrix. The Australian Vascular Biology Society 1999 Annual Scientific Meeting, 321003, 730106. Adelaide: The Aust. Vascular Biology Society 1999 Annual Scientific Meeting.
The influence of the small GTP-binding protein Rho on vascular smooth muscle cell phenotype
Worth, N., Rolfe, B. E., Campbell, G. R. and Campbell, J. H. (1999). The influence of the small GTP-binding protein Rho on vascular smooth muscle cell phenotype. Gold Coast, 27-30 Sept, 1999. Kent Town SA: Aust. Society for Biochemistry and Molecular Biology.
Early-Pregnancy Factor - a Suppressor Releasing Hormone
Rolfe, BE, Cavanagh, AC, Quinn, KA and Morton, H (1985). Early-Pregnancy Factor - a Suppressor Releasing Hormone. NEW YORK: WILEY-LISS.
Detection of An Epf-Like Substance in Sera of Patients with Testicular Germ-Cell Tumors
Gardiner, RA, Morton, H, Cavanagh, AC and Rolfe, BE (1984). Detection of An Epf-Like Substance in Sera of Patients with Testicular Germ-Cell Tumors. OXFORD: BLACKWELL SCIENCE LTD.
Early-Pregnancy Factor in Pre-Implantation Pregnancy
Morton, H, Rolfe, BE and Cavanagh, AC (1982). Early-Pregnancy Factor in Pre-Implantation Pregnancy. COPENHAGEN: MUNKSGAARD INT PUBL LTD.
Production of An Epf-Like Substance by Male Germ-Cell Tumors
Rolfe, BE, Morton, H, Cavanagh, AC and Gardiner, R (1982). Production of An Epf-Like Substance by Male Germ-Cell Tumors. COPENHAGEN: MUNKSGAARD INT PUBL LTD.
Early pregnancy factor: immunological, biochemical and clinical aspects
Rolfe, Barbara (1983). Early pregnancy factor: immunological, biochemical and clinical aspects. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland. doi: 10.14264/uql.2014.580
ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals
(2023–2028) ARC Industrial Transformation Research Hubs
(2022) Exopharm
Complement C5aR1: A novel therapeutic target for brain cancer
(2021–2023) Brain Cancer Innovation Project Grants
(2019–2023) NHMRC Development Grant
(2019) UQ Major Equipment and Infrastructure
A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
(2017–2018) UQ Major Equipment and Infrastructure
Targeting the Complement Cascade: A Novel Therapeutic Strategy for Metastatic Melanoma
(2016–2018) NHMRC Project Grant
(2015) UQ Major Equipment and Infrastructure
Complement C3a receptor, a novel therapeutic target for melanoma
(2014–2015) Cancer Council Queensland
Development of a rapid ex vivo screening assay for immunotoxicity of nanoparticles
(2014–2015) UQ Collaboration and Industry Engagement Fund - Seed Research Grant
(2011–2013) Wesley Merdical Research
(2010–2012) UQ Collaboration and Industry Engagement Fund
Establishment of a centralised live animal imaging fluorescence/bio-luminescence suite
(2010) UQ Major Equipment and Infrastructure
Cellular Mechanisms of Peritoneal Sclerosis
(2009–2010) Wesley Merdical Research
Origin of cells in the 'artificial' artery grown in the peritoneal cavity
(2005–2007) NHMRC Project Grant
Vascular smooth muscle cells of bone marrow origin - mechanisms of differentiation.
(2003–2004) National Heart Foundation of Australia
Human leukaemia factor as an anti-atherogenic agent
(2002–2003) Prince Charles Hospital Foundation
Non-lipid-lowering effects of statins: are they all beneficial?
(2002) Perpetual Trustee Company Limited
The signalling protein Rho as a regulator of smooth muscle cell phenotype: its role in atherogenesis
(2000–2001) National Heart Foundation of Australia
Leukaemia inhibitory factor: cellular mechanisms of action in the artery wall
(2000) Perpetual Trustee Company Limited
Leukaemia inhibitory factor: cellular mechanisms of action in the artery wall
(2000) Ronald Geoffrey Arnott Foundation
Human Leukaemia Inhibitory Factor (hLIF): A Potential Anti-Atherosclerotic/Anti-Restenotic Agent
(1998–2000) NHMRC Project Grant
Human leukaemia inhibitory factor as a potential inhibitor of restenosis
(1998–1999) Prince Charles Hospital Foundation
The Smooth Muscle Cell Cytoskeleton and its Role in Cell Phenotypic Change and AtherogenesisAN
(1998–1999) National Heart Foundation of Australia
Regulation of smooth muscle phenotype in atherosclerosis
(1998) Ramaciotti Foundation
(1997) UQ Travel Grants Scheme
T-lymphocytes and atherogenesis.
(1996–1998) National Heart Foundation of Australia
Equipment - Changes in smooth muscle proliferation and function in artherosclerosis
(1995) Ramaciotti Foundation
Non-immunological influences of T-cells in atherogenesis
(1995) Mayne Bequest Fund
Harnessing the Innate Immune System to Target Cancer: A Novel Immunotherapeutic Strategy for Solid Tumors
Doctor Philosophy — Principal Advisor
Other advisors:
Modulating the Mononuclear Phagocyte System for Improved Nanomaterial Delivery
Doctor Philosophy — Associate Advisor
Other advisors:
Targeting hypoxic cancer stem cells with nanoparticles
(2021) Doctor Philosophy — Principal Advisor
Other advisors:
Contribution of complement anaphylatoxin receptors to melanoma growth: potential therapeutic targets
(2016) Doctor Philosophy — Principal Advisor
Other advisors:
The Role of Transforming Growth Factor and Leukaemia Inhibitory Factor on Myofibroblast Differentiation in the Peritoneal Cavity
(2013) Doctor Philosophy — Principal Advisor
Characterisation of Myeloid Cells in the Peritoneal Foreign Body Response: Evidence for Phenotypic Plasticity
(2012) Doctor Philosophy — Principal Advisor
Other advisors:
Characterisation of Cells in the Foreign Body Response
(2008) Doctor Philosophy — Joint Principal Advisor
Application of clay nanoparticles as efficient adjuvant in vaccine against pathogenic diarrheagenic E. Coli
(2018) Doctor Philosophy — Associate Advisor
Other advisors:
(2018) Doctor Philosophy — Associate Advisor
Other advisors:
Physiological Response to Polymeric Materials in Nanomedicine
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
Controlled delivery of nanoparticles to the colon for tumour targeting
(2015) Doctor Philosophy — Associate Advisor
Other advisors:
(2014) Doctor Philosophy — Associate Advisor
Other advisors:
The influence of substrate creep on mesenchymal stem cell behaviour and phenotype
(2012) Doctor Philosophy — Associate Advisor
Other advisors:
Exercise, RhoA and Cardioprotection
(2011) Doctor Philosophy — Associate Advisor
Other advisors:
Defining the role of C5a in atherosclerosis
(2010) Doctor Philosophy — Associate Advisor
Ex vivo tissue vascularisation
(2010) Doctor Philosophy — Associate Advisor
Other advisors:
THE DEVELOPMENT OF ARTIFICIAL ARTERY AND ARTIFICIAL UTERUS FROM THE PERITONEAL-DERIVED TISSUE CAPSULE
(2004) Master Philosophy — Associate Advisor
THE MOLECULAR AND CELLULAR ACTIONS OF THE THERAPEUTIC CYTOKINE LIF ON THE VASCULATURE
(2004) Doctor Philosophy — Associate Advisor
TISSUE CAPSULE FORMATION IN THE PERITONEAL CAVITY
(2004) Master Philosophy — Associate Advisor
SMOOTH MUSCLE CELL CYTOSKELETAL PROTEINS AND REGULATION OF SMOOTH MUSCLE CELL PHENOTYPE
(2003) Doctor Philosophy — Associate Advisor
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.
The role of the complement system in tumour growth