Associate Professor Kristen Radford

Honorary Associate Professor

Mater Research Institute-UQ
Faculty of Medicine

Overview

A/Prof Kristen Radford is a Senior Research Fellow and NHMRC CDA Level 2 fellow. She completed her PhD in 1997 from the University of Newcastle, NSW and was awarded NSW Young Australian of the Year in 1998. She then undertook a postdoctoral position at Imperial Cancer Research Fund, London (now Cancer Research UK) developing new dendritic cell-based vaccine strategies for cancer immunotherapy. She joined Mater Research in 2001 and played a key role in obtaining the preclinical data that justified the first blood dendritic cell vaccine trial in prostate cancer that was completed in 2009. Her research interests are focussed on understanding basic dendritic cell biology in humans and applying this knowledge to develop more potent cancer vaccines.

Areas of expertise:

  • human immunology
  • dendritic cells
  • cancer immunology
  • immunotherapy
  • humanised mice

Techniques used / available:

  • humanised mice
  • flow cytometry
  • human immune cell isolation and function
  • human dendritic cell generation

Publications

  • Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019) MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, . doi:10.1038/s41388-019-0951-y

  • O’Brien, Liam J., Guillerey, Camille and Radford, Kristen J. (2019) Can Dendritic Cell vaccination prevent leukemia relapse?. Cancers, 11 6: 875. doi:10.3390/cancers11060875

  • Macri, Christophe, Fancke, Ben, Radford, Kristen J. and O’Keeffe, Meredith (2019). Monitoring dendritic cell activation and maturation. In Peter van Endert (Ed.), Antigen Processing 2nd ed. (pp. 403-418) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-9450-2_28

View all Publications

Supervision

View all Supervision

Publications

Book Chapter

  • Macri, Christophe, Fancke, Ben, Radford, Kristen J. and O’Keeffe, Meredith (2019). Monitoring dendritic cell activation and maturation. In Peter van Endert (Ed.), Antigen Processing 2nd ed. (pp. 403-418) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-9450-2_28

  • Lee, Yoke Seng and Radford, Kristen J. (2019). The role of dendritic cells in cancer. In Claire Lhuillier and Lorenzo Galluzzi (Ed.), International Review of Cell and Molecular Biology (pp. 123-178) Maryland Heights, MO, United States: Academic Press. doi:10.1016/bs.ircmb.2019.07.006

  • Radford, Kristen J., Shortman, Ken and O'Keefe, Meredith (2013). Dendritic cells in autoimmune disease. In Noel R. Rose and Ian R. Mackay (Ed.), The autoimmune diseases 5th ed. (pp. 175-186) San Diego, United States: Elsevier.

  • Kassianos, Andrew J., Jongbloed, Sarah L., Hart, Derek N.J. and Radford, Kristen J. (2010). Isolation of Human Blood DC Subtypes. In Shalin H. Naik (Ed.), Dendritic cell protocols 2nd ed. (pp. 45-54) New York , NY, U.S.A.: Humana Press. doi:10.1007/978-1-60761-421-0

  • Vulink, A., Radford, K. J., Melief, C. and Hart, D. N. J. (2008). Dendritic Cells in Cancer Immunotherapy. In Advances in Cancer Research (pp. 363-407) London, U.K.: Elsevier Inc.. doi:10.1016/S0065-230X(07)99006-5

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision