The University of Queensland

(Z)-N'-(1H-Benzo[d]imidazol-2-Yl)-arylimidamide adducts of 2-aminobenzimidazole and aromatic nitriles: structural and spectroscopic proof of regiochemical and stereochemical outcomes

Stoermer, Martin J., Egan, Simon, Forsyth, Craig M. and Moloney, Gerard P. (2019). (Z)-N'-(1H-Benzo[d]imidazol-2-Yl)-arylimidamide adducts of 2-aminobenzimidazole and aromatic nitriles: structural and spectroscopic proof of regiochemical and stereochemical outcomes.

Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular Clefts

Stoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Allan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2017). Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular Clefts. European Journal of Organic Chemistry, 2017 (45), 6793-6796. doi: 10.1002/ejoc.201701319

Orally absorbed cyclic peptides

Nielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2017). Orally absorbed cyclic peptides. Chemical Reviews, 117 (12), 8094-8128. doi: 10.1021/acs.chemrev.6b00838

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists

Seow, Vernon, Lim, Junxian, Cotterell, Adam J., Yau, Mei-Kwan, Xu, Weijun, Lohman, Rink-Jan, Kok, W. Mei, Stoermer, Martin J., Sweet, Matthew J., Reid, Robert C., Suen, Jacky Y. and Farilie, David P. (2016). Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. Scientific Reports, 6 (1) 24575, 24575.1-24575.12. doi: 10.1038/srep24575

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.

Shannon, A. E, Chappell, K. J., Stoermer, M. J., Chow, S. Y., Kok, W. M., Fairlie, D. P. and Young, P. R. (2015). Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.. Protein Expression and Purification, 119, 124-129. doi: 10.1016/j.pep.2015.11.022

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J, Tay, Stephanie, McMahon, Roisin M, Fairlie, David P and Martin, Jennifer L (2015). Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA. Plos One, 10 (7) e0133805, e0133805. doi: 10.1371/journal.pone.0133805

Three homology models for PAR2 derived from different templates: Application to antagonist discovery

Perry, Samuel R., Xu, Weijun, Wirija, Anna, Lim, Junxian, Yau, Mei-Kwan, Stoermer, Martin J., Lucke, Andrew J. and Fairlie, David P. (2015). Three homology models for PAR2 derived from different templates: Application to antagonist discovery. Journal of Chemical Information And Modeling, 55 (6), 1181-1191. doi: 10.1021/acs.jcim.5b00087

Potent heterocyclic ligands for human complement C3a receptor

Reid, Robert C., Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K., Lim, Junxian, Stoermer, Martin J. and Fairlie, David P. (2014). Potent heterocyclic ligands for human complement C3a receptor. Journal of Medicinal Chemistry, 57 (20), 8459-8470. doi: 10.1021/jm500956p

Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed

Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823

ChemInform Abstract: Lithium Perchlorate Accelerated Friedel-Crafts Addition of Furans to β-Nitrostyrenes

Stoermer, Martin J., Richter, Hans-Matthias and Kaufmann, Dieter E. (2014). ChemInform Abstract: Lithium Perchlorate Accelerated Friedel-Crafts Addition of Furans to β-Nitrostyrenes. ChemInform, 45 (15), no-no. doi: 10.1002/chin.201415112

Lithium perchlorate accelerated Friedel-Crafts addition of furans to β-nitrostyrenes

Stoermer, Martin J., Richter, Hans-Matthias and Kaufmann, Dieter E. (2013). Lithium perchlorate accelerated Friedel-Crafts addition of furans to β-nitrostyrenes. Tetrahedron Letters, 54 (49), 6776-6778. doi: 10.1016/j.tetlet.2013.10.018

Downsizing a human inflammatory protein to a small molecule with equal potency and functionality

Reid, Robert C., Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K., Reed, Anthony N., Chu, Peifei, Suen, Jacky Y., Stoermer, Martin J., Blakeney, Jade S., Lim, Junxian, Faber, Jonathan M. and David P. Fairlie, (2013). Downsizing a human inflammatory protein to a small molecule with equal potency and functionality. Nature Communications, 4 (2802) 2802, 1-9. doi: 10.1038/ncomms3802

An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein

Tan, Cindy S. E., Hobson-Peters, Jody M., Stoermer, Martin J., Fairlie, David P., Khromykh, Alexander A. and Hall, Roy A. (2013). An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein. Journal of General Virology, 94 (Pt. 9), 1961-1971. doi: 10.1099/vir.0.054395-0

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds

Ngoei, Kevin R. W., Ng, Dominic C. H., Gooley, Paul R., Fairlie, David P., Stoermer, Martin J. and Bogoyevitch, Marie A. (2013). Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1834 (6), 1077-1088. doi: 10.1016/j.bbapap.2013.02.001

Identification of crotonyl glycine in urine of sheep after 48h road transport

Li, Juan, Schirra, Horst Joachim, Yu, Yihua, Colgrave, Michelle L., Stoermer, Martin J. and Wijffels, Gene (2012). Identification of crotonyl glycine in urine of sheep after 48h road transport. Journal of Pharmaceutical and Biomedical Analysis, 67–68, 129-136. doi: 10.1016/j.jpba.2012.04.028

Structures of peptide agonists for human protease activated receptor 2

Stoermer, Martin J., Flanagan, Bernadine, Beyer, Renée L., Madala, Praveen K. and Fairlie, David P. (2012). Structures of peptide agonists for human protease activated receptor 2. Bioorganic and Medicinal Chemistry Letters, 22 (2), 916-919. doi: 10.1016/j.bmcl.2011.12.029

In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses

Kampmann, T., Yennamalli, R., Campbell, P., Stoermer, M. J., Fairlie, D. P., Kobe, B. and Young, P. R. (2009). In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses. Antiviral Research, 84 (3), 234-241. doi: 10.1016/j.antiviral.2009.09.007

Base-sensitivity of arginine alpha-ketoamide inhibitors of serine proteases

Stoermer, Martin J., Leung, Donmienne, Young, Paul R. and Fairlie, David P. (2009). Base-sensitivity of arginine alpha-ketoamide inhibitors of serine proteases. Australian Journal of Chemistry, 62 (9), 988-992. doi: 10.1071/CH09150

Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation

Robin, Gautier, Chappell, Keith, Stoermer, Martin J., Hu, Shu-Hong, Young, Paul R., Fairlie, David P. and Martin, Jennifer L. (2009). Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation. Journal of Molecular Biology, 385 (5), 1568-1577. doi: 10.1016/j.jmb.2008.11.026

West Nile Virus NS2B/NS3 protease as an antiviral target

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2008). West Nile Virus NS2B/NS3 protease as an antiviral target. Current Medicinal Chemistry, 15 (27), 2771-2784. doi: 10.2174/092986708786242804

Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity

Stoermer, Martin J., Chappell, Keith J., Liebscher, Susann, Jensen, Christina M., Gan, Chun H., Gupta, Praveer K., Xu, Wei-Jun, Young, Paul R. and Fairlie, David P. (2008). Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. Journal of Medicinal Chemistry, 51 (18), 5714-5721. doi: 10.1021/jm800503y

ChemInform Abstract: Synthesis and Cannabinoid Activity of 1-Substituted-indole-3-oxadiazole Derivatives: Novel Agonists for the CB1Receptor

Moloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). ChemInform Abstract: Synthesis and Cannabinoid Activity of 1-Substituted-indole-3-oxadiazole Derivatives: Novel Agonists for the CB1Receptor. ChemInform, 39 (31) doi: 10.1002/chin.200831222

Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

Chappell, Keith J., Stoermer, Martin J., Fairlie, David P. and Young, Paul R. (2008). Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity. Journal of General Virology, 89 (4), 1010-1014. doi: 10.1099/vir.0.83447-0

Synthesis and cannabinoid activity of 1-substituted-Indole-3-oxadiazole derivatives: Novel agonists for the CB1 Receptor

Moloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Lay, Lucy, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). Synthesis and cannabinoid activity of 1-substituted-Indole-3-oxadiazole derivatives: Novel agonists for the CB1 Receptor. European Journal of Medicinal Chemistry, 43 (3), 513-539. doi: 10.1016/j.ejmech.2007.04.007

Synthesis and cannabinoid activity of a variety of 2,3-substituted 1-Benzo[b]thiophen derivatives and 2,3-substituted benzofuran: Novel agonists for the CB1 receptor

Moloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Lay, Lucy, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). Synthesis and cannabinoid activity of a variety of 2,3-substituted 1-Benzo[b]thiophen derivatives and 2,3-substituted benzofuran: Novel agonists for the CB1 receptor. Australian Journal of Chemistry, 61 (7), 484-499. doi: 10.1071/CH07412

Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2007). Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3. Protein Expression and Purification, 53 (1), 87-96. doi: 10.1016/j.pep.2006.10.022

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006

Current Status of Virtual Screening as Analysed by Target Classes

Stoermer, M J (2006). Current Status of Virtual Screening as Analysed by Target Classes. Medicinal Chemistry, 2 (1), 89-112. doi: 10.2174/157340606775197750

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2006). Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. Journal of Biological Chemistry, 281 (50), 38448-38458. doi: 10.1074/jbc.M607641200

Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions

Chappell, Keith J., Nall, Tessa A., Stoermer, Martin J., Fang, Ning-Xia, Tyndall, Joel D. A., Fairlie, David P. and Young, Paul R. (2005). Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions. Journal of Biological Chemistry, 280 (4), 2896-2903. doi: 10.1074/jbc.M409931200

Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles

Singh, Y, Stoermer, MJ, Lucke, AJ, Guthrie, T and Fairlie, DP (2005). Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. Journal of The American Chemical Society, 127 (18), 6563-6572. doi: 10.1021/ja0455300

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease

Nall, T. A., Chappell, K. J., Stoermer, M. J., Fang, N. X., Tyndall, J. D. A., Young, P. R. and Fairlie, D. P. (2004). Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease. Journal of Biological Chemistry, 279 (47), 48535-48542. doi: 10.1074/jbc.M406810200

Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity

March, Darren R., Proctor, Lavinia M., Stoermer, Martin J., Sbaglia, Robert, Abbenante, Giovanni, Reid, Robert C., Woodruff, Trent M., Wadi, Khemar, Paczkowski, Natalii, Tyndall, Joel D. A., Taylor, Stephen M. and Fairlie, David P. (2004). Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity. Molecular Pharmacology, 65 (4), 868-879. doi: 10.1124/mol.65.4.868

Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles

Stoermer, M. J., Butler, D. N., Warrener, R. N., Weerasuria, K. D. V. and Fairlie, D. P. (2003). Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles. Chemistry-a European Journal, 9 (9), 2068-2071. doi: 10.1002/chem.200204619

Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles

Singh, Y, Stoermer, MJ, Lucke, AJ, Glenn, MP and Fairlie, DP (2002). Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. Organic Letters, 4 (20), 3367-3370. doi: 10.1021/ol026463m

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors

Leung, D., Schroder, K., White, H., Fang, N. X., Stoermer, M. J., Abbenante, G., Martin, J. L., Young, P. R. and Fairlie, D. P. (2001). Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. Journal of Biological Chemistry, 276 (49), 45762-45771. doi: 10.1074/jbc.M107360200

2-(Het)aryl-Substituted 7-Azabicyclo[2.2.1]heptane Systems

Otten, Albert, Namyslo, Jan Christoph, Stoermer, Martin and Kaufmann, Dieter E. (1998). 2-(Het)aryl-Substituted 7-Azabicyclo[2.2.1]heptane Systems. European Journal of Organic Chemistry, 1998 (9), 1997-2001. doi: 10.1002/(sici)1099-0690(199809)1998:9<1997::aid-ejoc1997>3.0.co;2-a

(E)-1-Bromo-2-methyl-4-phenyl-1-butene

Stoermer, Martin and Pinhey, John (1998). (E)-1-Bromo-2-methyl-4-phenyl-1-butene. Molecules, 3 (8), M58. doi: 10.3390/m58

(E)-2-Methyl-5-phenyl-2-pentenoic acid

Stoermer, Martin and Pinhey, John (1998). (E)-2-Methyl-5-phenyl-2-pentenoic acid. Molecules, 3 (3), M64. doi: 10.3390/m64

(E)-3-(2-Methoxyphenyl)-2-butenoic Acid

Stoermer, Martin and Pinhey, John (1998). (E)-3-(2-Methoxyphenyl)-2-butenoic Acid. Molecules, 3 (8), M73. doi: 10.3390/m73

(E)-3-Methyl-5-phenyl-2-pentenoic Acid

Stoermer, Martin and Pinhey, John (1998). (E)-3-Methyl-5-phenyl-2-pentenoic Acid. Molecules, 3 (8), M53. doi: 10.3390/m53

(Z)-2-Bromo-5-phenyl-2-pentene

Stoermer, Martin and Pinhey, John (1998). (Z)-2-Bromo-5-phenyl-2-pentene. Molecules, 3 (3), M66. doi: 10.3390/m66

(Z)-3-Methyl-5-phenyl-2-pentenoic Acid

Stoermer, Martin and Pinhey, John (1998). (Z)-3-Methyl-5-phenyl-2-pentenoic Acid. Molecules, 3 (8), M54. doi: 10.3390/m54

2(R,S),3(S,R)-2,3-Dibromo-3-methyl-5-phenyl-2-pentanoic Acid

Stoermer, Martin and Pinhey, John (1998). 2(R,S),3(S,R)-2,3-Dibromo-3-methyl-5-phenyl-2-pentanoic Acid. Molecules, 3 (3), M56. doi: 10.3390/m56

2(S,R),3(R,S)-2,3-Dibromo-3-methyl-5-phenyl-2-pentanoic Acid

Stoermer, Martin and Pinhey, John (1998). 2(S,R),3(R,S)-2,3-Dibromo-3-methyl-5-phenyl-2-pentanoic Acid. Molecules, 3 (8), M55. doi: 10.3390/m55

2,3-Dibromo-2-methyl-5-phenylpentanoic acid

Stoermer, Martin and Pinhey, John (1998). 2,3-Dibromo-2-methyl-5-phenylpentanoic acid. Molecules, 3 (3), M65. doi: 10.3390/m65

3-Hydroxy-3-methyl-5-phenylpentanoic acid

Stoermer, Martin and Pinhey, John (1998). 3-Hydroxy-3-methyl-5-phenylpentanoic acid. Molecules, 3 (3), M61. doi: 10.3390/m61

Ethyl (E)-2-Methyl-5-phenyl-2-pentenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (E)-2-Methyl-5-phenyl-2-pentenoate. Molecules, 3 (3), M62. doi: 10.3390/m62

Ethyl (E)-3-(2-Methoxyphenyl)-2-butenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (E)-3-(2-Methoxyphenyl)-2-butenoate. Molecules, 3 (3), M71. doi: 10.3390/m71

Ethyl (E)-3-methyl-5-phenyl-2-pentenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (E)-3-methyl-5-phenyl-2-pentenoate. Molecules, 3 (3), M51. doi: 10.3390/m51

Ethyl (Z)-2-Methyl-5-phenyl-2-pentenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (Z)-2-Methyl-5-phenyl-2-pentenoate. Molecules, 3 (8), M63. doi: 10.3390/m63

Ethyl (Z)-3-(2-Methoxyphenyl)-2-butenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (Z)-3-(2-Methoxyphenyl)-2-butenoate. Molecules, 3 (8), M72. doi: 10.3390/m72

Ethyl (Z)-3-Methyl-5-phenyl-2-pentenoate

Stoermer, Martin and Pinhey, John (1998). Ethyl (Z)-3-Methyl-5-phenyl-2-pentenoate. Molecules, 3 (8), M52. doi: 10.3390/m52

Ethyl 3-Acetoxy-3-methyl-5-phenylpentanoate

Stoermer, Martin and Pinhey, John (1998). Ethyl 3-Acetoxy-3-methyl-5-phenylpentanoate. Molecules, 3 (8), M60. doi: 10.3390/m60

Ethyl 3-Hydroxy-3-methyl-5-phenylpentanoate

Stoermer, Martin and Pinhey, John (1998). Ethyl 3-Hydroxy-3-methyl-5-phenylpentanoate. Molecules, 3 (8), M59. doi: 10.3390/m59

Tributyl-[(Z)-5-phenyl-2-penten-2-yl]stannane

Stoermer, Martin and Pinhey, John (1998). Tributyl-[(Z)-5-phenyl-2-penten-2-yl]stannane. Molecules, 3 (3), M67. doi: 10.3390/m67

[(Z)-5-Phenyl-2-penten-2-yl]mercury Acetate

Stoermer, Martin and Pinhey, John (1998). [(Z)-5-Phenyl-2-penten-2-yl]mercury Acetate. Molecules, 3 (8), M69. doi: 10.3390/m69

[(Z)-5-Phenyl-2-penten-2-yl]mercury Bromide

Stoermer, Martin and Pinhey, John (1998). [(Z)-5-Phenyl-2-penten-2-yl]mercury Bromide. Molecules, 3 (8), M68. doi: 10.3390/m68

bis-[(Z)-5-Phenyl-2-penten-2-yl]mercury

Stoermer, Martin and Pinhey, John (1998). bis-[(Z)-5-Phenyl-2-penten-2-yl]mercury. Molecules, 3 (3), M70. doi: 10.3390/m70

Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease.

Abbenante, G., Bergman, D. A., Brinkworth, R. I., March, D. R., Reid, R. C., Hunt, P. A., James, I. W., Dancer, R. J., Garnham, B., Stoermer, M. L. and Fairlie, D. P. (1996). Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease.. Bioorganic & Medicinal Chemistry Letters, 6 (21), 2531-2536. doi: 10.1016/0960-894X(96)00468-4

1H NMR evidence for the formation of vinyllead triacetates. The reactions of vinylmercury, vinyltin, and vinylboronic acids with lead tetraacetate

Parkinson, Christopher J. and Stoermer, Martin J. (1996). 1H NMR evidence for the formation of vinyllead triacetates. The reactions of vinylmercury, vinyltin, and vinylboronic acids with lead tetraacetate. Journal of Organometallic Chemistry, 507 (1-2), 207-214. doi: 10.1016/0022-328x(95)05746-c

A selective and versatile synthesis of substituted chromones via addition of phenols to dimethyl acetylenedicarboxylate

Stoermer, Martin J. and Fairlie, David P. (1995). A selective and versatile synthesis of substituted chromones via addition of phenols to dimethyl acetylenedicarboxylate. Australian Journal of Chemistry, 48 (3), 677-686. doi: 10.1071/CH9950677

Flavones are inhibitors of HIV-1 proteinase

Brinkworth R.I., Stoermer M.J. and Fairlie D.P. (1992). Flavones are inhibitors of HIV-1 proteinase. Biochemical and Biophysical Research Communications, 188 (2), 631-637. doi: 10.1016/0006-291X(92)91103-W

Electrophilic vinylations by vinyllead triacetates and tribenzoates generated by tin–lead exchange

Parkinson, Christopher J., Pinhey, John T. and Stoermer, Martin J. (1992). Electrophilic vinylations by vinyllead triacetates and tribenzoates generated by tin–lead exchange. Journal of the Chemical Society, Perkin Transactions 1 (15), 1911-1915. doi: 10.1039/p19920001911

Vinyl cation formation by decomposition of vinyllead(IV) triacetates. Part 2

Pinhey, John T. and Stoermer, Martin J. (1991). Vinyl cation formation by decomposition of vinyllead(IV) triacetates. Part 2. Journal of the Chemical Society, Perkin Transactions 1 (10), 2455-2460. doi: 10.1039/p19910002455

Vinyl cation formation by decomposition of vinyl-lead triacetates. The reactions of vinylmercury and vinyltin compounds with lead tetra-acetate

Moloney, Mark G., Pinhey, John T. and Stoermer, Martin J. (1990). Vinyl cation formation by decomposition of vinyl-lead triacetates. The reactions of vinylmercury and vinyltin compounds with lead tetra-acetate. Journal of the Chemical Society, Perkin Transactions 1 (10), 2645-2655. doi: 10.1039/p19900002645

Homology Models and Molecular Dynamics of SARS-CoV-2 Coronaviral Protease 3CLpro

Stoermer, Martin J. (2020). Homology Models and Molecular Dynamics of SARS-CoV-2 Coronaviral Protease 3CLpro. Royal Society of Chemistry Twitter Conference 2020, London (but held online), 3rd-4th March 2020. London, United Kingdom: Royal Society of Chemistry.

Molecular dynamics study of the UQ construct of West Nile Virus NS2B/NS3 protease and it’s interactions with inhibitors

Stoermer, Martin J. (2019). Molecular dynamics study of the UQ construct of West Nile Virus NS2B/NS3 protease and it’s interactions with inhibitors. 2019 Royal Society of Chemistry Twitter Conference, London (but held online), 5-6 March 2019. London, United Kingdom: Royal Society of Chemistry.

Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular clefts

Stoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Alan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2018). Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular clefts. 2018 Royal Society of Chemistry Twitter Conference, London, United Kingdom (held online), 6-7 March 2018. London, United Kingdom: Royal Society of Chemistry.

Flaviviral virus proteases. What do crystal structures and homology models actually tell us?

Stoermer, Martin J. (2017). Flaviviral virus proteases. What do crystal structures and homology models actually tell us?. Royal Society of Chemistry Twitter Conference 2017, London (but held online), 20-21 March 2017. London, United Kingdom: Royal Society of Chemistry. doi: 10.6084/m9.figshare.7823423

Why are there so few Australian chemists on Twitter?

Stoermer, Martin (2016). Why are there so few Australian chemists on Twitter?. Queensland Annual Chemistry Symposium, Hawken Building, University of Queensland, 25th November 2016. doi: 10.6084/m9.figshare.7849403

Downsizing Proteins Without Losing Potency or Function

Fairlie, David P. , Yau, Mei-Kwan , Hamidon, Johan K. , Singh, Ranee , Lim, Junxian , Suen, Jacky Y. , Rowley, Jessica A. , Lohman, Rink-Jan , Stoermer, Martin J. , Iyer, Abishek and Reid, Robert C. (2015). Downsizing Proteins Without Losing Potency or Function. American Peptide Symposium 2015, Orlando , Florida, United States, 20-25 June 2015. American Peptide Society. doi: 10.17952/24APS.2015.016

Mining physicochemical features that contribute to oral bioavailability in peptide middle space

Plisson, Fabien , Lucke, Andrew, Nielsen, Daniel , Stoermer, Martin J. and Fairlie, David (2014). Mining physicochemical features that contribute to oral bioavailability in peptide middle space. European QSAR Symposium, St Petersburg, Russia, September 2014.

Novel inhibitors of DENV NS2B/NS3pro protease

Chow, Shiao Yun, Stoermer, Martin J., Chappell, Keith J., Young, Paul R. and Fairlie, David P. (2013). Novel inhibitors of DENV NS2B/NS3pro protease. 246th National Meeting of the American-Chemical-Society (ACS), Indianapolis in, Sep 08-12, 2013. WASHINGTON: AMER CHEMICAL SOC.

Toward more orally bioavailable inhibitors of phospholipase A(2) GIIA (pla2g2a) to treat chronic inflammation

Barbero, Sheila, Reid, Robert C., Stoermer, Martin J., Lohman, Rink J. and Fairlie, David P. (2013). Toward more orally bioavailable inhibitors of phospholipase A(2) GIIA (pla2g2a) to treat chronic inflammation. 246th National Meeting of the American-Chemical-Society (ACS), Indianapolis, IN, United States, 8-12 September 2013. Washington, DC, United States: American Chemical Society.

Towards orally bioavailable peptides and peptidomimetics

Fairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, 27-31 March 2011. Washington, DC, United States: American Chemical Society.

Identification of crotonyl glycine in sheep urine using RP-HPLC, NMR and ESI-MS

Li, J., Wijffels, G., Colgrave, M., Stoermer, M.J. and Schirra, H.J. (2010). Identification of crotonyl glycine in sheep urine using RP-HPLC, NMR and ESI-MS. Metabolomics and More - 1st International Metabolomics Symposium in Germany, Freising, Germany, 10-12 March, 2010.

Potent inhibitors of West Nile Virus NS2B/NS3 protease

Chappell, K. J., Fairlie, D. P., Gan, C. H., Gupta, P. K., Hu, S., Jensen, C. M., Liebscher, S., Martin, J. L., Robin, G., Stoermer M. J., Xu, W. and Young, P. R. (2010). Potent inhibitors of West Nile Virus NS2B/NS3 protease. 6th General Meeting of the International Proteolysis Society, Gold Coast, QLD, Australia, 26-30 October 2009. Berlin, Germany: Walter De Gruyter.

Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates

Liebscher, Susan, Chappell, K. J., Stoermer, Martin J., Watterson, Daniel, Webb, Richard I., Khromykh, Alexander A., Fairlie, David P. and Young, Paul R. (2010). Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates. PlusStrand 2010: The Ninth International Symposium on Positive-Strand RNA Viruses, Atlanta, GA, U.S.A., 17-21 May 2010.

Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 protease

Liebscher, S., Chappell, K.J., Stoermer, M.J., Fairlie, D.P. and Young, P.R (2009). Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 protease. 6th General Meeting of the International Proteolysis Society, Gold Coast , QLD, Australia, 26-30 October, 2009.

Potent inhibitors of West Nile Virus NS2B/NS3 protease

Stoermer, Martin , Chappell, Keith J. , Jensen, Christina M. , Liebscher, Susann , Gan, Chun H. , Gupta, Praveer K. , Xu, Wei-Jun , Young, Paul R. , Fairlie, David P. and Watterson, Dan (2009). Potent inhibitors of West Nile Virus NS2B/NS3 protease. 6th General Meeting of the International Proteolysis Society, Gold Coast, QLD, Australia, 26-30 October 2009.

Regulating protein and peptide activated GPCRs

Fairlie, David P., Madala, Praveen K., Stoermer, Martin J., Suen, Jacky, Barry, Grant and Lohman, Rink-Jan (2009). Regulating protein and peptide activated GPCRs. 229th National Meeting of the American Chemical Society, San Diego, California, 13-17 March 2005. Washington DC, United States: American Chemical Society.

COMP 264-Unraveling the mechanism of antagonism for human C5a receptor: Comparison of three structurally different antagonists

Madala, P. K., Stoermer, M., Tyndall, J. D. A., Monk, P. N., Higginbottom, A. and Fairlie, D. P. (2008). COMP 264-Unraveling the mechanism of antagonism for human C5a receptor: Comparison of three structurally different antagonists. 236th National Meeting of the American Chemical Society, Philadelphia, USA, 17-21 August, 2008. Washington, D. C., USA: American Chemical Society.

Defining the ligand binding site on the human C5a receptor

Monk, Peter N., Higginbottom, Adrian, Madala, Praveen K., Tyndall, Joel D. A., Stoermer, Martin and Fairlie, David P. (2006). Defining the ligand binding site on the human C5a receptor. 231st National Meeting of the American-Chemical-Society, Atlanta Ga, Mar 26-30, 2006. WASHINGTON: AMER CHEMICAL SOC.

Defining the ligand binding site on the human C5a receptor

Monk, Peter N., Higginbottom, Adrian, Madala, Praveen K., Tyndall, Joel D. A., Stoermer, Martin and Fairlie, David P. (2006). Defining the ligand binding site on the human C5a receptor. The 231st ACS National Meeting, Atlanta, GA, U.S.A., 26-30 March 2006. Washington, D.C.: American Chemical Society.

Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification

Chappell, K. J., Stoermer, M J, Fairlie, D and Young, P R (2006). Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Qld, 2-6 July, 2006.

Multiple targets for antiviral inhibitors

Young, P. R., Chappell, K. J., Stoermer, M. J., Fairlie, D., Kampmann, T. and Kobe, B. (2006). Multiple targets for antiviral inhibitors. 7th Asia Pacific Congress of Virology, New Delhi, 13-15 Nov, 2006.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. 30th Lorne Conference on Protein Structure & Function, Lorne, 6-10 Feb, 2005.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. International Congress of Virology, San Francisco, 23-27 July, 2005.

Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis. 3rd Australian Virology Group Meeting, Phillip Island, Vic., 9-12 Dec, 2005.

Development of antiviral drugs targeting the flavivirus fusion mechanism

Kampmann, T., Yennamalli Madhava R, R., Stoermer, M. J., Kobe, B. and Young, P. R. (2005). Development of antiviral drugs targeting the flavivirus fusion mechanism. 30th Lorne Conference on Protein Structure & Function, Lorne, 6-10 Feb, 2005.

Development of antiviral drugs targeting the flaviviruses fusion mechanism

Kampmann, T., Yennamalli, R., Stoermer, M., Kobe, B. and Young, P. (2005). Development of antiviral drugs targeting the flaviviruses fusion mechanism. 30th FEBS Congress - 9th IUBMB Conference, Budapest, Hungary, 2-7tJuly 2005. Oxford, England: Blackwell Publishing. doi: 10.1111/j.1742-4658.2005.4739_15.x

Discovery of antiviral inhibitors targeting the fusion mechanism of the flavivirus family members Dengue, Kunjin and Yellow fever

Kampmann, T., Yennamalli Madhava R, R., Stoermer, M. J., Kobe, B. and Young, P. R. (2005). Discovery of antiviral inhibitors targeting the fusion mechanism of the flavivirus family members Dengue, Kunjin and Yellow fever. 30th FEBS Congress - 9th Int Union of Biochem & Molecular Biof, Budapest, 2-7 July, 2005.

Template-assembled peptide loops, helices, sheets and nanofibres

Fairlie, DP, Singh, Y, Sharpe, P and Stoermer, M (2003). Template-assembled peptide loops, helices, sheets and nanofibres. 225th National Meeting of the American-Chemical-Society, New Orleans Louisiana, Mar 23-27, 2003. WASHINGTON: AMER CHEMICAL SOC.

Macrocyclic peptides as ligands for cellular receptors. When a little rigidity is just right...

Martin J. Stoermer (2003). Macrocyclic peptides as ligands for cellular receptors. When a little rigidity is just right.... Brisbane Biological and Organic Symposium (BBOCS) 2003, Brisbane, 28 November 2003. doi: 10.6084/m9.figshare.7849310

Template-assembled peptide loops, helices, sheets, and nanofibers

Fairlie, David P ., Singh, Yogendra, Sharpe, Philip and Stoermer, Martin (2003). Template-assembled peptide loops, helices, sheets, and nanofibers. 225th ACS National Meeting, New Orleans, LA, United States, 23-27 March 2003.

Are ketoamides suitable electrophilic isosteres for incorporation in inhibitors of serine proteases?

Stoermer, Martin , Leung, Donmienne and Fairlie, David (2001). Are ketoamides suitable electrophilic isosteres for incorporation in inhibitors of serine proteases?. Brisbane Biological & Organic Chemistry Symposium 2001(BBOCS 2001), University of Queensland, Australia, 30 November, 2001.

In vitro catalytic activity of recombinant forms of the dengue virus NS3 protease

Young, P. R., Fang, N., Leung, D., Arakaki, T., Stoermer, M. J., Fairlie, D. and Martin, J. L. (2001). In vitro catalytic activity of recombinant forms of the dengue virus NS3 protease. 6th International Symposium on Positive Strand Viruses, Paris, France, 28 May - 2 June, 2001.

Inhibition of Human Secretory Phospholipase A2 (Type IIA)

Clark, Chris , Reid, Bob , Hansford, Karl , Stoermer, Martin and Fairlie, David (2000). Inhibition of Human Secretory Phospholipase A2 (Type IIA). First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November 2000.

Synthesis, SAR, and Pharmacological Activities of a Series of Tyrosine-Derived Inhibitors of Human Nonpancreatic Secretory Phospholipase A2

Hansford, Karl A. , Clark, Chris I. , Reid, Robert C. , Stoermer, Martin J. , Shiels, Ian , Taylor, Stephen and Fairlie, David P. (2000). Synthesis, SAR, and Pharmacological Activities of a Series of Tyrosine-Derived Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November 2000.

Towards Arginine Mimetics

Stoermer, Martin and Fairlie, David (2000). Towards Arginine Mimetics. The First Brisbane Biological and Organic Chemistry Symposium, Griifith University, Brisbane, Queensland, Australia, 27th November 2000. doi: 10.6084/m9.figshare.7836131

Modelling Studies Of Molecular Receptors

Chalmers, David K., Stoermer, Martin J. and Fairlie, David P. (1998). Modelling Studies Of Molecular Receptors. Royal Australian Chemical Institute 16th National Organic Chemistry Conference, Leura, Blue Mountains, New South Wales, 12-17 July 1998.

Design and synthesis of inhibitors of HIV-1 protease

Abbenante, Gioavanni , March, Darren , Reid, Robert , Stoermer, Martin , West, Michael , Bergmann, Doug , Alewood, Dianne , Alewood, Paul and Fairlie, David (1994). Design and synthesis of inhibitors of HIV-1 protease. 14th National Conference of the Royal Australian Chemical Institute, Division of Organic Chemistry , University of Wollongong, NSW, Australia, 1994.

Design and synthesis of new cavitands which are stereochemically rigid, hydrophobic and internally functionalised

Stoermer, Martin and Fairle, David (1993). Design and synthesis of new cavitands which are stereochemically rigid, hydrophobic and internally functionalised. Royal Australian Chemical Institute, Division of Medicinal and Agricultural Chemistry and the New Zealand Chemical Institute Conference, Auckland, New Zealand, 1993.

A selective and versatile synthesis of substituted chromones via addition of phenols to dimethyl acetylenedicarboxylate

Stoermer, Martin J. and Fairlie, David P. (1992). A selective and versatile synthesis of substituted chromones via addition of phenols to dimethyl acetylenedicarboxylate. 13th National Conference of the Royal Australian Chemical Institute, Division of Organic Chemistry , Monash University, Melbourne, 1992.

Design and synthesis of new cavitands which are stereochemically rigid, hydrophobic and internally functionalised

Stoermer, M.J., Wickramasinghe, W., Weerasuria, K.D.V., Fairlie, D., Butler, D. and Warrener, R. (1992). Design and synthesis of new cavitands which are stereochemically rigid, hydrophobic and internally functionalised. Royal Australian Chemical Institute National Conference 1992, Monash University, Melbourne, Australia, 28 Sept - 2 October 1992.

Synthesis of cavitands as catalytic environments

Stoermer, Martin J. and Fairlie, David P. (1991). Synthesis of cavitands as catalytic environments. 12th National Conference of the Royal Australian Chemical Institute, Division of Organic Chemistry, University of Queensland, Australia, 1991.

The alpha-vinylation of beta-dicarbonyl compounds via vinyllead triacetates

Stoermer, Martin J. (1990). The alpha-vinylation of beta-dicarbonyl compounds via vinyllead triacetates. Royal Australian Chemical Institute, Fifth Brisbane Organic Chemistry Symposium (BOCS), Griffith University, Brisbane, Australia, 1990.

Vinyllead triacetates: a source of vinyl cations or alkylidene carbenes?

Stoermer, Martin J. and Pinhey, John T. (1989). Vinyllead triacetates: a source of vinyl cations or alkylidene carbenes?. 11th National Conference of the Royal Australian Chemical Institute, Division of Organic Chemistry , James Cook University of North Queensland, Townsville, 1989.

Generation of vinyl cations from vinyllead triacetates

Stoermer, Martin J. , Moloney, Mark L. and Pinhey, John T. (1986). Generation of vinyl cations from vinyllead triacetates. 9th National Conference of the Royal Australian Chemical Institute, Division of Organic Chemistry , University of Adelaide and Flinders University, South Australia, 1986.

Homology Models of the Papain-Like Protease PLpro from Coronavirus 2019-nCoV

Stoermer, Martin J. (2020). Homology Models of the Papain-Like Protease PLpro from Coronavirus 2019-nCoV.

Homology Models of Coronavirus 2019-nCoV 3CLpro Protease

Stoermer, Martin J. (2020). Homology Models of Coronavirus 2019-nCoV 3CLpro Protease.

Supporting Raw Molecular Dynamics Data for Homology models of Coronavirus 2019-nCoV 3CLpro Protease

Stoermer, Martin J. (2020). Supporting Raw Molecular Dynamics Data for Homology models of Coronavirus 2019-nCoV 3CLpro Protease. The University of Queensland. (Dataset) doi: 10.14264/uql.2020.155

Supplementary Data tables for: Orally absorbed cyclic peptides

Nielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2019). Supplementary Data tables for: Orally absorbed cyclic peptides. The University of Queensland. (Dataset) doi: 10.14264/uql.2019.213

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P., Fairlie, David P. and Schafer, Karl (2007). Compounds and inhibitors of phospholipases. US7253194.

New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis

Clark, C. I., Fairlie, D. P., Hansford, K., McGeary, R. P., Reid, R. C. and Stoermer, M. J. (2007). New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis.

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P., Fairlie, David P. and Schafer, Karl (2004). Compounds and inhibitors of phospholipases. US2004033995.

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P. and Fairlie, David P. (2002). Compounds and inhibitors of phospholipases. WO0208189.