Honorary Professor Theo Sloots

Honorary Professor

Child Health Research Centre
Faculty of Medicine

Overview

Professor Theo Sloots is a PhD graduate in Microbiology, with a special interest in molecular microbiology and medical virology. He is the Director of Research at the Queensland Paediatric Infectious Diseases (QPID) laboratory at the Queensland Children’s Medical Research Institute, Brisbane. His laboratory conducts basic and applied research in infectious diseases, particularly respiratory and gastrointestinal infections, applies molecular technology to the diagnosis and characterisation of microorganisms, and investigates undiagnosed infectious disease in children. The QPID laboratory is considered a Centre of Excellence in diagnostic microbiology. Over the last 10 years Prof Sloots has attracted research funding in excess of $14 million from external granting bodies such as the NHMRC, ARC, NIH and the Children’s Health Foundation. He has published extensively with 205 scientific articles in peer-reviewed journals and books.He is a Fellow of the Australian Society for Microbiology and a Foundation Fellow, Faculty of Science (RCPA).

Research Impacts

Research conducted by Professor Sloots has significant clinical impact on health care within the State and nationally. It has resulted in a major paradigm shift in the diagnosis of infectious disease in Queensland Health which has directly benefited the Queensland population. It has underpinned the establishment and maintenance of a novel molecular diagnostic service at the Pathology Queensland Central laboratory, which is unique in Australia. This research has resulted in the award of two international patents which are currently undergoing commercial development.

Together with international collaborators, Prof Sloots has been responsible for the discovery of new viruses, or virus species, associated with the human respiratory tract which has enhanced our understanding of respiratory disease, and has initiated further research into the biology and pathogenesis of these new viral agents.

In addition, the laboratory supervised by Prof Sloots has made an international contribution to the understanding of molecular drug resistance mechanisms of human pathogens, particularly the pathogenic Neisseria.

Qualifications

  • Postgraduate Certificate in Management, Queensland University of Technology
  • Doctor of Philosophy, The University of Queensland
  • Master of Science, The University of Queensland
  • Bachelor of Science, The University of Queensland

Publications

View all Publications

Publications

Book Chapter

  • Rockett, Rebecca J., Nissen, Michael D., Sloots, Theo P. and Bialasiewicz, Seweryn (2016). Human polyomaviruses. Clinical Virology Manual. (pp. 427-442) edited by Michael J. Loeffelholz, Richard L. Hodinka, Stephen A. Young and Benjamin A. Pinsky. Washington DC, United States: American Society for Microbiology (ASM). doi: 10.1128/9781555819156

  • Whiley, David M. and Sloots, Theo P. (2016). Molecular amplification methods in diagnostic virology. Lennette's laboratory diagnosis of viral infections. (pp. 19-39) edited by Keith R. Jerome. Boca Raton, FL, United States: CRC Press.

  • Liang, Fang, Arora, Neetika, Zhang, Kang Liang, Yeh, David Che Cheng, Lai, Richard, Pearson, Darnley, Barnett, Graeme, Whiley, David, Sloots, Theo, Corrie, Simon R. and Barnard, Ross T. (2013). A new, multiplex, quantitative real-time polymerase chain reaction system for nucleic acid detection and quantification. Nucleic acid detection: methods and protocols. (pp. 51-68) edited by Dmitry M. Kolpashchikov and Yulia V. Gerasimova. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-535-4_4

  • Goire, Namraj, Sloots, Theo P., Whiley, David M. and Nissen, Michael D. (2012). Protocol for the molecular detection of antibiotic resistance mechanisms in Neisseria gonorrhoeae. Diagnosis of sexually transmitted diseases. (pp. 319-328) edited by Colin R. MacKenzie and Birgit Henrich. Heidelberg, Germany: Springer. doi: 10.1007/978-1-61779-937-2_22

  • Bialasiewicz, Seweryn, Mackay, Ian M., Whiley, David M. and Sloots, Theo P. (2012). Protocol for the use of enzyme-linked hybridization assays for genital ulcer disease. Diagnosis of sexually transmitted diseases. (pp. 225-233) edited by Colin R. MacKenzie and Birgit Henrich. New York, NY, United States: Humana Press. doi: 10.1007/978-1-61779-937-2_14

  • Bialasiewicz, Seweryn, Whiley, David M. and Sloots, Theo P. (2010). Malaria (P. falciparum, P. vivax, P. malariae, P. ovale). PCR for clinical microbiology : An Australian and international perspective. (pp. 373-377) edited by Margaret Schuller, Theo P. Sloots, Gregory S. James, Catriona L. Halliday and Ian W.J. Carter. Dordrecht ; London: Springer Publishing. doi: 10.1007/978-90-481-9039-3_64

  • Nissen, Michael D., Lambert, Stephen B., Whiley, David M. and Sloots, Theo P. (2010). Respiratory infections. PCR for clinical microbiology: an Australian and international perspective. (pp. 67-82) edited by Margret Schuller, Theo P. Sloots, Gregory S. James, Catriona L. Halliday and Ian W. J. Carter. Dordrecht, Netherlands : Springer. doi: 10.1007/978-90-481-9039-3_5

  • Mackay, I. M., Arden, K. E., Nissen, M. D. and Sloots, T. P. (2007). Challenges Facing Real-time PCR Characterization of Acute Respiratory Tract Infections.. Real-Time PCR in Microbiology from Diagnosis to Characterization.. (pp. 269-318) edited by Mackay, I.M.. United Kingdom: Horizon Press - Calister Academic Press.

  • Beld, M. G. H. M., Mackay, I. M., Sloots, T. P. and et. al. (2007). Experts' roundtable: Real time PCR and microbiology. Real-Time PCR in Microbiology From diagnosis to characterization. (pp. 357-444) edited by Ian M. Mackay. Norfolk, United Kingdom: Caister Academic.

  • Mackay I M, Bustin, S. A., Andrade, J. M., Kubista, M and Sloots, T P (2007). Quantification of Microorganisms: not Human, not Simple, not Quick.. Real-Time PCR in Microbiology From Diagnosis to Characterization.. (pp. 133-182) edited by Mackay, I. M.. United Kingdom: Horizon Press - Calister Academic Press.

  • Mackay, I. M., Mackay, J. F., Nissen, M. D. and Sloots, T. P. (2007). Real-time PCR; History and Fluorgenic Chemistries. Real-Time PCR in Microbiology From diagnosis to characterization. (pp. 1-40) edited by Mackay, I. M.. United Kingdom: Horizon Press - Calister Academic Press.

  • Whiley, D. M. and Sloots, T. P. (2006). Clinical Virology. Real-Time PCR. (pp. 231-276) edited by M. Tevfik Dorak. UK: Taylor & Francis.

  • Ratcliff, M., Chang, G., Kok, T. W. and Sloots, T. P. (2006). Molecular diagnosis of medical viruses. Current Technology and Applicantions. (pp. 269-298) edited by Juluri R. Rao, Colin C. Fleming and John E. Moore. Norfold, United Kingdom: Horizon Bioscience.

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Completed Supervision