The University of Queensland

Cardiac troponin T and I: back to basics

Mingels, Alma M., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Thielmann, Matthias (2023). Cardiac troponin T and I: back to basics. European Heart Journal: Acute Cardiovascular Care, 12 (9), 631-632. doi: 10.1093/ehjacc/zuad084

Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol

Schults, Jessica A., Marsh, Nicole, Ullman, Amanda J., Kleidon, Tricia M., Ware, Robert S., Byrnes, Joshua, Young, Emily, Hall, Lisa, Keijzers, Gerben, Cullen, Louise, Calleja, Pauline, McTaggart, Steven, Peters, Nathan, Watkins, Stuart, Corley, Amanda, Brown, Christine, Lin, Zhen, Williamson, Frances, Burgess, Luke, Macfarlane, Fiona, Cooke, Marie, Battley, Callan and Rickard, Claire M. (2023). Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol. BMC Health Services Research, 23 (1) 587, 1-12. doi: 10.1186/s12913-023-09499-0

Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome

Stephensen, Laura, Greenslade, Jaimi, Starmer, Katrina, Starmer, Greg, Stone, Richard, Bonnin, Robert, Brazzale, Anthony, Drahm‐Butler, Tileah, Campbell, Virginia, Davis, Tania, Mowatt, Elizabeth, Brown, Nathan, Proctor, Karlie, Ashover, Sarah, Milburn, Tanya, McCormack, Louise, Graves, Nicholas, Gatton, Michelle, Mahoney, Ray, Parsonage, William and Cullen, Louise (2023). Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome. Emergency Medicine Australasia, 35 (3), 442-449. doi: 10.1111/1742-6723.14138

Healthcare cost burden of acute chest pain presentations

Dawson, Luke, Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew, Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2023). Healthcare cost burden of acute chest pain presentations. Emergency Medicine Journal, 40 (6) emermed-2022-212674, 1-7. doi: 10.1136/emermed-2022-212674

High-sensitivity cardiac troponin in stable atherosclerotic vascular disease

Morrow, David A., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Thielmann, Matthias (2023). High-sensitivity cardiac troponin in stable atherosclerotic vascular disease. European Heart Journal: Acute Cardiovascular Care, 12 (6), 396-398. doi: 10.1093/ehjacc/zuad054

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

Doudesis, Dimitrios, Lee, Kuan Ken, Boeddinghaus, Jasper, Bularga, Anda, Ferry, Amy V., Tuck, Chris, Lowry, Matthew T. H., Lopez-Ayala, Pedro, Nestelberger, Thomas, Koechlin, Luca, Bernabeu, Miguel O., Neubeck, Lis, Anand, Atul, Schulz, Karen, Apple, Fred S., Parsonage, William, Greenslade, Jaimi H., Cullen, Louise, Pickering, John W., Than, Martin P., Gray, Alasdair, Mueller, Christian, Mills, Nicholas L., Richards, A. Mark, Pemberton, Chris, Troughton, Richard W., Aldous, Sally J., Brown, Anthony F. T., Dalton, Emily ... CoDE-ACS Investigators (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29 (5), 1201-1210. doi: 10.1038/s41591-023-02325-4

Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study

Fabre-Estremera, Blanca, Smith, Stephen W., Sandoval, Yader, Schulz, Karen, Okeson, Brynn, Cullen, Louise and Apple, Fred S. (2023). Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study. Clinical Chemistry, 69 (6), 627-636. doi: 10.1093/clinchem/hvad033

Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey

Brownlee, Emily, Greenslade, Jaimi H, Kelly, Anne‐Maree, Meek, Robert A, Parsonage, William A and Cullen, Louise (2023). Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey. Emergency Medicine Australasia, 35 (2), 261-268. doi: 10.1111/1742-6723.14115

Sex differences in epidemiology, care, and outcomes in patients with acute chest pain

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Davis, Esther, Bloom, Jason, Cox, Shelley, Nelson, Adam J., Okyere, Daniel, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew J., Nicholls, Stephen J., Cullen, Louise, Kaye, David, Smith, Karen and Stub, Dion (2023). Sex differences in epidemiology, care, and outcomes in patients with acute chest pain. Journal of the American College of Cardiology, 81 (10), 933-945. doi: 10.1016/j.jacc.2022.12.025

Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research

Platz, Elke, Morrow, David A, Verbrugge, Frederik H, Vranckx, Pascal and Cullen, Louise (2023). Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research. European Heart Journal. Acute Cardiovascular Care, 12 (2), 77-79. doi: 10.1093/ehjacc/zuac170

Chest pain management using prehospital point-of-care troponin and paramedic risk assessment

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Ball, Jocasta, Zhou, Jennifer, Lefkovits, Jeffrey, Taylor, Andrew J., Horrigan, Mark, Chew, Derek P., Kaye, David, Cullen, Louise, Mihalopoulos, Cathrine, Smith, Karen and Stub, Dion (2023). Chest pain management using prehospital point-of-care troponin and paramedic risk assessment. JAMA Internal Medicine, 183 (3), 203-211. doi: 10.1001/jamainternmed.2022.6409

Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: Interactions between low troponin concentrations and participant sex within two randomized clinical trials

Lambrakis, Kristina, Khan, Ehsan, van den Merkhof, Anke, Papendick, Cynthia, Chuang, Anthony, Zhai, Yuze, Eng-Frost, Joanne, Rocheleau, Simon, Lehman, Sam J., Blyth, Andrew, Briffa, Tom, Quinn, Stephen, French, John K., Cullen, Louise and Chew, Derek P. (2023). Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: Interactions between low troponin concentrations and participant sex within two randomized clinical trials. International Journal of Cardiology, 393 131396, 131396. doi: 10.1016/j.ijcard.2023.131396

Personalized diagnosis in suspected myocardial infarction

Neumann, Johannes Tobias, Twerenbold, Raphael, Ojeda, Francisco, Aldous, Sally J., Allen, Brandon R., Apple, Fred S., Babel, Hugo, Christenson, Robert H., Cullen, Louise, Di Carluccio, Eleonora, Doudesis, Dimitrios, Ekelund, Ulf, Giannitsis, Evangelos, Greenslade, Jaimi, Inoue, Kenji, Jernberg, Tomas, Kavsak, Peter, Keller, Till, Lee, Kuan Ken, Lindahl, Bertil, Lorenz, Thiess, Mahler, Simon A., Mills, Nicholas L., Mokhtari, Arash, Parsonage, William, Pickering, John W., Pemberton, Christopher J., Reich, Christoph, Richards, A. Mark ... Zournazi, Anna (2023). Personalized diagnosis in suspected myocardial infarction. Clinical Research in Cardiology, 112 (9), 1288-1301. doi: 10.1007/s00392-023-02206-3

Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay

Meek, Robert, Cullen, Louise, Lu, Zhong, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2023). Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay. EMA - Emergency Medicine Australasia, 35 (6), 1005-1012. doi: 10.1111/1742-6723.14282

Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

Apple, Fred S., Smith, Stephen W., Greenslade, Jaimi H., Sandoval, Yader, Parsonage, William, Ranasinghe, Isuru, Gaikwad, Niranjan J, Schulz, Karen, Stephensen, Laura, Schmidt, Christian W., Okeson, Brynn and Cullen, Louise (2022). Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk. Circulation, 146 (25), 1918-1929. doi: 10.1161/circulationaha.122.061148

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain

Eggers, Kai M., Hammarsten, Ola, Aldous, Sally J., Cullen, Louise, Greenslade, Jaimi H., Lindahl, Bertil, Parsonage, William A., Pemberton, Christopher J., Pickering, John W., Richards, A. Mark, Troughton, Richard W. and Than, Martin P. (2022). Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain. PLoS One, 17 (11) e0276645, 1-14. doi: 10.1371/journal.pone.0276645

Machine learning to optimise use of cardiac troponin in the diagnosis of acute myocardial infarction

Doudesis, D, Lee, K K, Bularga, A, Ferry, A V, Tuck, C, Anand, A, Boeddinghaus, J, Mueller, C, Greenslade, J H, Pickering, J W, Than, M P, Cullen, L and Mills, N L (2022). Machine learning to optimise use of cardiac troponin in the diagnosis of acute myocardial infarction. European Heart Journal, 43 (Supplement_2). doi: 10.1093/eurheartj/ehac544.1349

Performance of the American Heart Association/American College of Cardiology/Heart Rhythm Society versus European Society of Cardiology guideline criteria for hospital admission of patients with syncope

du Fay de Lavallaz, Jeanne, Zimmermann, Tobias, Badertscher, Patrick, Lopez-Ayala, Pedro, Nestelberger, Thomas, Miró, Òscar, Salgado, Emilio, Zaytseva, Xenia, Gafner, Michele Sara, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Sigal, Alan, Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Strebel, Ivo, Schuler, Sereina, Manka, Robert, Bilici, Murat, Lohrmann, Jens, Kühne, Michael, Breidthardt, Tobias, Clark, Carol L. ... Storrow, Alan B. (2022). Performance of the American Heart Association/American College of Cardiology/Heart Rhythm Society versus European Society of Cardiology guideline criteria for hospital admission of patients with syncope. Heart Rhythm, 19 (10), 1712-1722. doi: 10.1016/j.hrthm.2022.05.024

The retirement of CKMB

Jaffe, Allan S., Mills, Nicholas L., Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin and Thygesen, Kristian (2022). The retirement of CKMB. European Heart Journal: Acute Cardiovascular Care, 11 (10), 784-785. doi: 10.1093/ehjacc/zuac113

Clinical utility of D-dimer for rule-out or rule-in of venous thromboembolism in syncope

Badertscher, Patrick, du Fay de Lavallaz, Jeanne, Hammerer-Lercher, Angelika, Mueller, Christian, Zimmermann, Tobias, Lopez-Ayala, Pedro, Nestelberger, Thomas, Gualandro, Danielle M., Miró, Òscar, Keller, Dagmar I., Martin-Sanchez, F. Javier, Bürgler, Franz, Than, Martin, Widmer, Velina, Christ, Michael, Cullen, Louise, Di Somma, Salvatore, Peacock, W. Frank, Geigy, Nicolas, Kühne, Michael, Freese, Michael, Salgado, Emilio, Martinez-Nadal, Gemma, Inostroza, Carolina Isabel Fuenzalida, Costabel, Juan Pablo, Mandrión, José Bustamante, Poepping, Imke, Rentsch, Katharina, von Eckardstein, Arnold ... Lohrmann, Jens (2022). Clinical utility of D-dimer for rule-out or rule-in of venous thromboembolism in syncope. Journal of Cardiovascular Translational Research, 16 (2), 427-429. doi: 10.1007/s12265-022-10306-0

Diagnoses and trends in use of imaging for low back pain in four Australian emergency departments between 2012 and 2019

Blokzijl, Johan, Lee, Hopin, Cullen, Louise, Coggins, Andrew, Golding, Michael, Gillett, Mark, Middleton, Paul M, Ferreira, Giovanni E, Machado, Gustavo C, Maher, Christopher G and Traeger, Adrian C (2022). Diagnoses and trends in use of imaging for low back pain in four Australian emergency departments between 2012 and 2019. Emergency Medicine Australasia, 34 (4), 539-546. doi: 10.1111/1742-6723.13928

Chest pain workup in the presence of atrial fibrillation: impacts on troponin testing, myocardial infarction diagnoses, and long-term prognosis

Lancini, Daniel, Greenslade, Jaimi, Martin, Paul, Prasad, Sandhir, Atherton, John, Parsonage, William, Aldous, Sally, Than, Martin and Cullen, Louise (2022). Chest pain workup in the presence of atrial fibrillation: impacts on troponin testing, myocardial infarction diagnoses, and long-term prognosis. European Heart Journal. Acute Cardiovascular Care, 11 (10), 772-781. doi: 10.1093/ehjacc/zuac090

Emergency department assessment of suspected acute coronary syndrome using the IMPACT pathway in Aboriginal and Torres Strait Islander people

Cullen, Louise, Stephensen, Laura, Greenslade, Jaimi, Starmer, Katrina, Starmer, Greg, Stone, Richard, Bonnin, Robert, Brazzale, Anthony, Drahm-Butler, Tileah, Campbell, Virginia, Davis, Tania, Mowatt, Elizabeth, Brown, Nathan J., Proctor, Karlie, Ashover, Sarah, Milburn, Tanya, McCormack, Louise, Graves, Nicholas and Parsonage, William (2022). Emergency department assessment of suspected acute coronary syndrome using the IMPACT pathway in Aboriginal and Torres Strait Islander people. Heart Lung and Circulation, 31 (7), 1029-1036. doi: 10.1016/j.hlc.2022.02.010

Care models for acute chest pain that improve outcomes and efficiency: JACC state-of-the-art review

Dawson, Luke P., Smith, Karen, Cullen, Louise, Nehme, Ziad, Lefkovits, Jeffrey, Taylor, Andrew J. and Stub, Dion (2022). Care models for acute chest pain that improve outcomes and efficiency: JACC state-of-the-art review. Journal of the American College of Cardiology, 79 (23), 2333-2348. doi: 10.1016/j.jacc.2022.03.380

Development and validation of a comprehensive early risk prediction model for patients with undifferentiated acute chest pain

Dawson, Luke P., Andrew, Emily, Nehme, Ziad, Bloom, Jason, Liew, Danny, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew J., Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2022). Development and validation of a comprehensive early risk prediction model for patients with undifferentiated acute chest pain. IJC Heart and Vasculature, 40 101043. doi: 10.1016/j.ijcha.2022.101043

International validation of the Canadian Syncope Risk Score: a cohort study

Zimmermann, Tobias, de Lavallaz, Jeanne du Fay, Nestelberger, Thomas, Gualandro, Danielle M., Lopez-Ayala, Pedro, Badertscher, Patrick, Widmer, Velina, Shrestha, Samyut, Strebel, Ivo, Glarner, Noemi, Diebold, Matthias, Miró, Òscar, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Bilici, Murat, Costabel, Juan Pablo, Kühne, Michael, Breidthardt, Tobias, Thiruganasambandamoorthy, Venkatesh, Mueller, Christian and BASEL IX Investigators† (2022). International validation of the Canadian Syncope Risk Score: a cohort study. Annals of Internal Medicine, 175 (6), 783-794. doi: 10.7326/m21-2313

Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease

Rajkumar, Christopher A., Wereski, Ryan, Parsonage, William, Cullen, Louise, Khamis, Ramzi, Foley, Michael, Harrell, Frank E., Shun-Shin, Matthew J., Mills, Nicholas L. and Al-Lamee, Rasha K. (2022). Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease. Journal of the American College of Cardiology, 79 (21), 2185-2187. doi: 10.1016/j.jacc.2022.03.369

Value of single troponin values in the emergency department for excluding acute myocardial infarction in Aboriginal and Torres Strait Islander people

Greenslade, Jaimi H., Berndt, Sara, Stephensen, Laura, Starmer, Katrina, Starmer, Greg, Parsonage, William, Lau, Victor, Drahm‐Butler, Tileah, Davis, Tania, Campbell, Virginia, Stone, Richard, Bonnin, Robert, Ashover, Sarah, Milburn, Tanya, Mowatt, Elizabeth, Proctor, Karlie, Brazzale, Anthony and Cullen, Louise Ann (2022). Value of single troponin values in the emergency department for excluding acute myocardial infarction in Aboriginal and Torres Strait Islander people. Medical Journal of Australia, 217 (1), 48-49. doi: 10.5694/mja2.51544

From little things, big things grow: An exploratory analysis of the national cost of peripheral intravenous catheter insertion in Australian adult emergency care

Morgan, Rachel, Callander, Emily, Cullen, Louise, Walker, Katie, Bumpstead, Suzanne, Hawkins, Tracey, Kuhn, Lisa and Egerton-Warburton, Diana (2022). From little things, big things grow: An exploratory analysis of the national cost of peripheral intravenous catheter insertion in Australian adult emergency care. EMA - Emergency Medicine Australasia, 34 (6), 877-883. doi: 10.1111/1742-6723.14009

The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction–from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC)

Mair, Johannes, Jaffe, Allan, Lindahl, Bertil, Mills, Nicholas, Möckel, Martin, Cullen, Louise, Giannitsis, Evangelos, Hammarsten, Ola, Huber, Kurt, Krychtiuk, Konstantin, Mueller, Christian and Thygesen, Kristian (2022). The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction–from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC). Biomarkers, 27 (5), 407-417. doi: 10.1080/1354750X.2022.2055792

Use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in the emergency department

Daniels, Lori B, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Jaffe, Allan S., Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin and Thygesen, Kristian (2022). Use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in the emergency department. European Heart Journal: Acute Cardiovascular Care, 11 (5), 440-441. doi: 10.1093/ehjacc/zuac042

The intra-individual variation of cardiac troponin I: the effects of sex, age, climatic season, and time between samples

Koerbin, Gus, Potter, Julia M., Pinto Do Nascimento, Marcela, Cullen, Louise, Scanlan, Samuel L., Woods, Catherine and Hickman, Peter E. (2022). The intra-individual variation of cardiac troponin I: the effects of sex, age, climatic season, and time between samples. Clinical Chemistry and Laboratory Medicine, 60 (7), 1101-1109. doi: 10.1515/cclm-2022-0125

What is an acceptable risk of major adverse cardiac event soon after discharge from emergency? the patient’s perspective

Greenslade, Jaimi H, Wilkinson, Sarah, Parsonage, William and Cullen, Louise (2022). What is an acceptable risk of major adverse cardiac event soon after discharge from emergency? the patient’s perspective. Emergency Medicine Journal, 39 (7) 212251, 519-520. doi: 10.1136/emermed-2021-212251

Troponins in myocardial infarction and injury

Potter, Julia M., Hickman, Peter E. and Cullen, Louise (2022). Troponins in myocardial infarction and injury. Australian Prescriber, 45 (2), 53-57. doi: 10.18773/austprescr.2022.006

Biomarker development in cardiology: Reviewing the past to inform the future

Kott, Katharine A., Bishop, Michael, Yang, Christina H. J., Plasto, Toby M., Cheng, Daniel C., Kaplan, Adam I., Cullen, Louise, Celermajer, David S., Meikle, Peter J., Vernon, Stephen T. and Figtree, Gemma A. (2022). Biomarker development in cardiology: Reviewing the past to inform the future. Cells, 11 (3) 588. doi: 10.3390/cells11030588

Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial

Chuang, Ming-yu Anthony, Gnanamanickam, Emmanuel S., Karnon, Jonathan, Lambrakis, Kristina, Horsfall, Matthew, Blyth, Andrew, Seshadri, Anil, Nguyen, Mau T., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, French, John K. and Chew, Derek P. (2022). Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial. IJC Heart and Vasculature, 38 100933. doi: 10.1016/j.ijcha.2021.100933

Implementation of more sensitive cardiac troponin T assay in a state-wide health service

Khan, Ehsan, Lambrakis, Kristina, Nazir, Sheraz A., Chuang, Anthony, Halabi, Amera, Tiver, Kathryn, Briffa, Tom, Cullen, Louise A., Horsfall, Matthew, French, John K., Sun, Benjamin C. and Chew, Derek P. (2022). Implementation of more sensitive cardiac troponin T assay in a state-wide health service. International Journal of Cardiology, 347, 66-72. doi: 10.1016/j.ijcard.2021.11.013

Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

Cullen, Louise, Collinson, Paul O. and Giannitsis, Evangelos (2022). Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities. Emergency Medicine Journal, 39 (11) emermed-2021-211907, 861-866. doi: 10.1136/emermed-2021-211907

Retrospective study of the prevalence and characteristics of adverse drug events in adults who present to an Australian emergency department

Brown, Nathan J., Doran, Elizabeth, Greenslade, Jaimi H., Lukin, Bill, Cottrell, Neil, Jaramillo, Fabian, Coombes, Ian, Donovan, Peter and Cullen, Louise (2022). Retrospective study of the prevalence and characteristics of adverse drug events in adults who present to an Australian emergency department. Emergency Medicine Australasia, 34 (4), 547-554. doi: 10.1111/1742-6723.13929

How to implement novel diagnostic algorithms for non-ST-segment elevation myocardial infarction in the emergency department

Cullen, Louise, Mills, Nicholas L, Morrow, David A and Mueller, Christian (2021). How to implement novel diagnostic algorithms for non-ST-segment elevation myocardial infarction in the emergency department. European Heart Journal. Acute Cardiovascular Care, 11 (1), 75-76. doi: 10.1093/ehjacc/zuab118

Chest pain assessment: what is our endgame?

Cullen, Louise, Greenslade, Jaimi and Parsonage, William (2021). Chest pain assessment: what is our endgame?. Clinical Chemistry, 68 (2), 261-263. doi: 10.1093/clinchem/hvab246

Applying a framework to assess the impact of cardiovascular outcomes improvement research

Sarkies, Mitchell N., Robinson, Suzanne, Briffa, Tom, Duffy, Stephen J., Nelson, Mark, Beltrame, John, Cullen, Louise, Chew, Derek, Smith, Julian, Brieger, David, Macdonald, Peter, Liew, Danny and Reid, Chris (2021). Applying a framework to assess the impact of cardiovascular outcomes improvement research. Health Research Policy and Systems, 19 (1) 67, 1-12. doi: 10.1186/s12961-021-00710-4

Evaluation of the Atellica TnIH cardiac troponin i assay and assessment of biological equivalence

Pretorius, Carel J., Parsonage, William, Cullen, Louise W., Wilgen, Urs, De Waal, Elzahn, Klingberg, Sandra, Dimeski, Goce, White, Rob, Greenslade, Jaimi and Ungerer, Jacobus P.J. (2021). Evaluation of the Atellica TnIH cardiac troponin i assay and assessment of biological equivalence. Clinical Chemistry and Laboratory Medicine, 60 (2) 0991, 283-290. doi: 10.1515/cclm-2021-0991

Potential impact of a novel pathway for suspected myocardial infarction utilising a new high-sensitivity cardiac troponin I assay

Meek, Rob, Cullen, Louise, Lu, Zhong Xian, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2021). Potential impact of a novel pathway for suspected myocardial infarction utilising a new high-sensitivity cardiac troponin I assay. Emergency Medicine Journal, 39 (11), 1-6. doi: 10.1136/emermed-2020-210812

Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain

Sharma, Sweekriti, Traeger, Adrian C., Tcharkhedian, Elise, Middleton, Paul M., Cullen, Louise and Maher, Chris G. (2021). Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain. International Journal for Quality in Health Care, 33 (4) mzab129, 1-11. doi: 10.1093/intqhc/mzab129

Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria

Dodd, Kenneth W., Zvosec, Deborah L., Hart, Michael A., Glass, George, Bannister, Laura E., Body, Richard M., Boggust, Brett A., Brady, William J., Chang, Anna M., Cullen, Louise, Gómez-Vicente, Rafael, Huis in ‘t Veld, Maite A., Karim, Rehan M., Meyers, H. Pendell, Miranda, David F., Mitchell, Gary J., Reynard, Charles, Rice, Clifford, Salverda, Bayert J., Stellpflug, Samuel J., Tolia, Vaishal M., Walsh, Brooks M., White, Jennifer L., Smith, Stephen W., Smith, Stephen W., Dodd, Kenneth W., Zvosec, Deborah L., Karim, Rehan M., Hart, Michael A. ... on behalf of the PERFECT study investigators (2021). Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria. Annals of Emergency Medicine, 78 (4), 517-529. doi: 10.1016/j.annemergmed.2021.03.036

Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle‐Branch Block

Nestelberger, Thomas, Boeddinghaus, Jasper, Lopez Ayala, Pedro, Gehrke, Juliane, Twerenbold, Raphael, Cullen, Louise, Mueller, Christian, Strebel, Ivo, Prepoudis, Alexandra, Gualandro, Danielle M., Puelacher, Christian, du Fay Lavallaz, Jeanne, Frey, Simon Martin, Ratmann, Paul David, Arslani, Ketina, Walter, Joan Elias, Freese, Michael, Shrestha, Samyut, Belkin, Maria, Koechlin, Luca, Hillinger, Petra, Potlukova, Eliska, Rentsch, Katharina, Mitrovic, Sandra, Kawecki, Damian, Morawiec, Beata, Munzk, Piotr, Geigy, Nicolas, Reichlin, Tobias ... on behalf of the APACE, ADAPT, TRAPID- AMI Investigators (2021). Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle‐Branch Block. Journal of the American Heart Association, 10 (18) e021262. doi: 10.1161/jaha.121.021262

Is a nudge all we need to promote deliberate clinical inertia and thoughtful clinical decision making?

Foster, Mieke, Egerton‐Warburton, Diana, Cullen, Louise, Fatovich, Daniel M. and Keijzers, Gerben (2021). Is a nudge all we need to promote deliberate clinical inertia and thoughtful clinical decision making?. Emergency Medicine Australasia, 33 (4), 748-752. doi: 10.1111/1742-6723.13782

Classification performance of clinical risk scoring in suspected acute coronary syndrome beyond a rule-out troponin profile

Khan, Ehsan, Lambrakis, Kristina, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, Horsfall, Matthew, Morton, Erin, French, John K., Papendick, Cynthia, Nelson, Adam J. and Chew, Derek P. (2021). Classification performance of clinical risk scoring in suspected acute coronary syndrome beyond a rule-out troponin profile. European Heart Journal. Acute Cardiovascular Care, 10 (9), 1038-1047. doi: 10.1093/ehjacc/zuab040

ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: a fond farewell at the retirement of CKMB

Jaffe, Allan S, Lindahl, Bertil, Giannitsis, Evangelos, Mueller, Christian, Cullen, Louise, Hammarsten, Ola, Mockel, Martin, Mair, Johannes, Krychtiuk, Konstantin A, Huber, Kurt, Mills, Nicholas L and Thygesen, Kristian (2021). ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: a fond farewell at the retirement of CKMB. European Heart Journal, 42 (23), 2260-2264. doi: 10.1093/eurheartj/ehaa1079

Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS

Lambrakis, Kristina, Papendick, Cynthia, French, John K., Quinn, Stephen, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J.R., Chuang, Anthony, Khan, Ehsan, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, Karnon, Jonathan, Briffa, Tom, Cullen, Louise A. and Chew, Derek P. (2021). Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS. Circulation, 144 (2), 113-125. doi: 10.1161/CIRCULATIONAHA.121.055009

Cardiovascular biomarkers in patients with COVID-19

Mueller, Christian, Giannitsis, Evangelos, Jaffe, Allan S., Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Mills, Nicholas L., Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Lindahl, Bertil and ESC Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association (2021). Cardiovascular biomarkers in patients with COVID-19. European Heart Journal. Acute Cardiovascular Care, 10 (3), 310-319. doi: 10.1093/ehjacc/zuab009

Development of an electrocardiogram-based risk calculator for a cardiac cause of syncope

Zimmermann, Tobias, du Fay de Lavallaz, Jeanne, Walter, Joan Elias, Strebel, Ivo, Nestelberger, Thomas, Joray, Lydia, Badertscher, Patrick, Flores, Dayana, Widmer, Velina, Geigy, Nicolas, Miro, Oscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martín-Sánchez, Francisco Javier, Di Somma, Salvatore, Peacock, W Frank, Keller, Dagmar, Costabel, Juan Pablo, Wussler, Desiree Nadine, Kawecki, Damian, Lohrmann, Jens, Gualandro, Danielle Menosi, Kuehne, Michael, Reichlin, Tobias, Sun, Benjamin and Mueller, Christian (2021). Development of an electrocardiogram-based risk calculator for a cardiac cause of syncope. Heart, 107 (22), 1796-1804. doi: 10.1136/heartjnl-2020-318430

Incidence, characteristics, determinants, and prognostic impact of recurrent syncope

Zimmermann, Tobias, du Fay de Lavallaz, Jeanne, Nestelberger, Thomas, Gualandro, Danielle M., Strebel, Ivo, Badertscher, Patrick, Lopez-Ayala, Pedro, Widmer, Velina, Freese, Michael, Miró, Òscar, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W Frank, Keller, Dagmar I., Boeddinghaus, Jasper, Twerenbold, Raphael, Wussler, Desiree, Koechlin, Luca, Walter, Joan E., Bürgler, Franz, Geigy, Nicolas, Kühne, Michael, Reichlin, Tobias, Lohrmann, Jens and Mueller, Christian (2020). Incidence, characteristics, determinants, and prognostic impact of recurrent syncope. Europace, 22 (12), 1885-1895. doi: 10.1093/europace/euaa227

Using Sex‐specific Cutoffs for High‐sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction

Peacock, W. Frank, Baumann, Brigitte M., Rivers, E. Joy, Davis, Thomas E., Handy, Beverly, Jones, Christopher W., Hollander, Judd E., Limkakeng, Alexander T., Mehrotra, Abhi, Than, Martin, Cullen, Louise, Ziegler, André and Dinkel‐Keuthage, Carina (2020). Using Sex‐specific Cutoffs for High‐sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction. Academic Emergency Medicine, 28 (4), 463-466. doi: 10.1111/acem.14098

Risk stratification scores for patients with acute heart failure in the Emergency Department: A systematic review

Miró, Òscar, Rossello, Xavier, Platz, Elke, Masip, Josep, Gualandro, Danielle M., Peacock, W. Frank, Price, Susanna, Cullen, Louise, DiSomma, Salvatore, de Oliveira Jr, Mucio Tavares, McMurray, John J. V., Martín-Sánchez, Francisco J., Maisel, Alan S., Vrints, Christiaan, Cowie, Martin R., Bueno, Héctor, Mebazaa, Alexandre, Mueller, Christian and The Study Group on Acute Heart Failure of the Acute Cardiovascular Care Association of the European Society of Cardiology (2020). Risk stratification scores for patients with acute heart failure in the Emergency Department: A systematic review. European Heart Journal. Acute Cardiovascular Care, 9 (5), 375-398. doi: 10.1177/2048872620930889

CSANZ Position Statement on the Evaluation of Patients Presenting With Suspected Acute Coronary Syndromes During the COVID-19 Pandemic

Parsonage, William A., Cullen, Louise, Brieger, David, Hillis, Graham S., Nasis, Arthur, Dwyer, Nathan, Wahi, Sudhir, Lo, Sidney, Than, Martin, Kerr, Andrew, Devlin, Gerard and Chew, Derek K. (2020). CSANZ Position Statement on the Evaluation of Patients Presenting With Suspected Acute Coronary Syndromes During the COVID-19 Pandemic. Heart, Lung and Circulation, 29 (7), e105-e110. doi: 10.1016/j.hlc.2020.05.003

Widespread introduction of a high-sensitivity troponin assay: assessing the impact on patients and health services

Greenslade, Jaimi H., Parsonage, William, Foran, Laura, McCormack, Louise, Ashover, Sarah, Milburn, Tanya, Berndt, Sara, Than, Martin, Brain, David and Cullen, Louise (2020). Widespread introduction of a high-sensitivity troponin assay: assessing the impact on patients and health services. Journal of Clinical Medicine, 9 (6) 1883, 1-12. doi: 10.3390/jcm9061883

Application of the fourth universal definition of myocardial infarction in clinical practice

Mair, Johannes, Cullen, Louise, Giannitsis, Evangelos, Hammarsten, Ola, Huber, Kurt, Jaffe, Allan, Mills, Nicholas, Möckel, Martin, Müller, Christian, Thygesen, Kristian and Lindahl, Bertil (2020). Application of the fourth universal definition of myocardial infarction in clinical practice. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 25 (4), 322-330. doi: 10.1080/1354750X.2020.1764108

Examining the translational success of an initiative to accelerate the assessment of chest pain for patients in an Australian emergency department: A pre-post study

Greenslade, Jaimi H., Ho, Ariel, Hawkins, Tracey, Parsonage, William, Crilly, Julia and Cullen, Louise (2020). Examining the translational success of an initiative to accelerate the assessment of chest pain for patients in an Australian emergency department: A pre-post study. BMC Health Services Research, 20 (1) 419, 1-9. doi: 10.1186/s12913-020-05296-1

Facilitators and barriers for emergency department clinicians using a rapid chest pain assessment protocol: qualitative interview research

Crilly, Julia, Greenslade, Jaimi H., Berndt, Sara, Hawkins, Tracey and Cullen, Louise (2020). Facilitators and barriers for emergency department clinicians using a rapid chest pain assessment protocol: qualitative interview research. BMC Health Services Research, 20 (1) 74, 1-11. doi: 10.1186/s12913-020-4923-2

Factors influencing physician risk estimates for acute cardiac events in emergency patients with suspected acute coronary syndrome

Greenslade, Jaimi H., Sieben, Nicolas, Parsonage, William A., Knowlman, Thomas, Ruane, Lorcan, Than, Martin, Pickering, John W., Hawkins, Tracey and Cullen, Louise (2019). Factors influencing physician risk estimates for acute cardiac events in emergency patients with suspected acute coronary syndrome. Emergency Medicine Journal, 37 (1), 2-7. doi: 10.1136/emermed-2019-208916

A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT)

Chew, Derek P., Lambrakis, Kristina, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, Karnon, Jonathan, Chuang, Anthony, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, French, John K. and Papendick, Cynthia (2019). A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT). Circulation, 140 (19), 1543-1556. doi: 10.1161/CIRCULATIONAHA.119.042891

Two-hour algorithm for rapid triage of suspected acute myocardial infarction using a high-sensitivity cardiac troponin I assay

Nestelberger, Thomas, Boeddinghaus, Jasper, Greenslade, Jaimi, Parsonage, William A., Than, Martin, Wussler, Desiree, Lopez-Ayala, Pedro, Zimmermann, Tobias, Meier, Mario, Troester, Valentina, Badertscher, Patrick, Koechlin, Luca, Wildi, Karin, Anwar, Mahnoor, Freese, Michael, Keller, Dagmar, Reichlin, Tobias, Twerenbold, Raphael, Cullen, Louise and Mueller, Christian (2019). Two-hour algorithm for rapid triage of suspected acute myocardial infarction using a high-sensitivity cardiac troponin I assay. Clinical Chemistry, 65 (11), 1437-1447. doi: 10.1373/clinchem.2019.305193

Diagnosis of acute myocardial infarction in the presence of left bundle branch block

Nestelberger, Thomas, Cullen, Louise, Lindahl, Bertil, Reichlin, Tobias, Greenslade, Jaimi H., Giannitsis, Evangelos, Christ, Michael, Morawiec, Beata, Miro, Oscar, Martín-Sánchez, Francisco Javier, Wussler, Desiree Nadine, Koechlin, Luca, Twerenbold, Raphael, Parsonage, William, Boeddinghaus, Jasper, Rubini Gimenez, Maria, Puelacher, Christian, Wildi, Karin, Buerge, Tobias, Badertscher, Patrick, DuFaydeLavallaz, Jeanne, Strebel, Ivo, Croton, Lukas, Bendig, Garnet, Osswald, Stefan, Pickering, John William, Than, Martin, Mueller, Christian and APACE, ADAPT and TRAPID-AMI Investigators (2019). Diagnosis of acute myocardial infarction in the presence of left bundle branch block. Heart, 105 (20), 1559-1567. doi: 10.1136/heartjnl-2018-314673

Letter by Egerton-Warburton et al Regarding Article, “Duration of Electrocardiographic Monitoring of Emergency Department Patients With Syncope”

Egerton-Warburton, Diana, Maclean, Patrick and Cullen, Louise (2019). Letter by Egerton-Warburton et al Regarding Article, “Duration of Electrocardiographic Monitoring of Emergency Department Patients With Syncope”. Circulation, 140 (12). doi: 10.1161/circulationaha.119.040717

Machine Learning to Predict the Likelihood of Acute Myocardial Infarction

Than, Martin P., Pickering, John W., Sandoval, Yader, Shah, Anoop S.V., Tsanas, Athanasios, Apple, Fred S., Blankenberg, Stefan, Cullen, Louise, Mueller, Christian, Neumann, Johannes T., Twerenbold, Raphael, Westermann, Dirk, Beshiri, Agim, Mills, Nicholas L., George, Peter M., Richards, A Mark, Troughton, Richard W., Aldous, Sally J., Chapman, Andrew R., Anand, Atul, Greenslade, Jaimi, Parsonage, William, Boeddinghaus, Jasper, Wildi, Karin, Nestelberger, Thomas, Badertscher, Patrick, Du, Shaoqing, Huang, Janel, Smith, Stephen W. ... On behalf of the MI Collaborative (2019). Machine Learning to Predict the Likelihood of Acute Myocardial Infarction. Circulation, 140 (11), 899-909. doi: 10.1161/circulationaha.119.041980

Prevalence of pulmonary embolism in patients with syncope

Badertscher, Patrick, du Fay de Lavallaz, Jeanne, Hammerer-Lercher, Angelika, Nestelberger, Thomas, Zimmermann, Tobias, Geiger, Marc, Imahorn, Orell, Miró, Òscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Walter, Joan, Boeddinghaus, Jasper, Twerenbold, Raphael, Méndez, Adriana, Gospodinov, Boris, Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Kawecki, Damian, Geigy, Nicolas, Strebel, Ivo, Lohrmann, Jens ... Osswald, Stefan (2019). Prevalence of pulmonary embolism in patients with syncope. Journal of the American College of Cardiology, 74 (6), 744-754. doi: 10.1016/j.jacc.2019.06.020

Application of high-sensitivity troponin in suspected myocardial infarction

Neumann, Johannes T., Twerenbold, Raphael, Ojeda, Francisco, Sörensen, Nils A., Chapman, Andrew R., Shah, Anoop S.V., Anand, Atul, Boeddinghaus, Jasper, Nestelberger, Thomas, Badertscher, Patrick, Mokhtari, Arash, Pickering, John W., Troughton, Richard W., Greenslade, Jaimi, Parsonage, William, Mueller-Hennessen, Matthias, Gori, Tommaso, Jernberg, Tomas, Morris, Niall, Liebetrau, Christoph, Hamm, Christian, Katus, Hugo A., Münzel, Thomas, Landmesser, Ulf, Salomaa, Veikko, Iacoviello, Licia, Ferrario, Marco M., Giampaoli, Simona, Kee, Frank ... Blankenberg, Stefan (2019). Application of high-sensitivity troponin in suspected myocardial infarction. New England Journal of Medicine, 380 (26), 2529-2540. doi: 10.1056/nejmoa1803377

Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure

Platz, Elke, Jhund, Pardeep S., Girerd, Nicolas, Pivetta, Emanuele, McMurray, John J.V., Peacock, W. Frank, Masip, Josep, Martin‐Sanchez, Francisco Javier, Miró, Òscar, Price, Susanna, Cullen, Louise, Maisel, Alan S., Vrints, Christiaan, Cowie, Martin R., DiSomma, Salvatore, Bueno, Hector, Mebazaa, Alexandre, Gualandro, Danielle M., Tavares, Mucio, Metra, Marco, Coats, Andrew J.S., Ruschitzka, Frank, Seferovic, Petar M., Mueller, Christian and on behalf of the Study Group on Acute Heart Failure of the Acute Cardiovascular Care Association and the Heart Failure Association of the European Society of Cardiology (2019). Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure. European Journal of Heart Failure, 21 (7), 844-851. doi: 10.1002/ejhf.1499

B-Type Natriuretic Peptides and Cardiac Troponins for Diagnosis and Risk-Stratification of Syncope

du Fay de Lavallaz, Jeanne, Badertscher, Patrick, Nestelberger, Thomas, Zimmermann, Tobias, Miró, Òscar, Salgado, Emilio, Christ, Michael, Geigy, Nicolas, Cullen, Louise, Than, Martin, Javier Martin-Sanchez, F., Di Somma, Salvatore, Frank Peacock, W., Morawiec, Beata, Walter, Joan, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, Boeddinghaus, Jasper, Koechlin, Luca, Strebel, Ivo, Keller, Dagmar I., Lohrmann, Jens, Michou, Eleni, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola ... For the BASEL IX Investigators (2019). B-Type Natriuretic Peptides and Cardiac Troponins for Diagnosis and Risk-Stratification of Syncope. Circulation, 139 (21), 2403-2418. doi: 10.1161/circulationaha.118.038358

Recognizing the potential for overdiagnosis: are high-sensitivity cardiac troponin assays an example?

Bell, Katy J. L., Doust, Jenny, Glasziou, Paul, Cullen, Louise, Harris, Ian A., Smith, Leon, Buchbinder, Rachelle and Barratt, Alexandra (2019). Recognizing the potential for overdiagnosis: are high-sensitivity cardiac troponin assays an example?. Annals of Internal Medicine, 170 (4), 259-+. doi: 10.7326/M18-2645

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Validity of a novel point-of-care troponin assay for single-test rule-out of acute myocardial infarction

Pickering, John W., Young, Joanna M., George, Peter M., Watson, Antony S., Aldous, Sally J., Troughton, Richard W., Pemberton, Christopher J., Richards, A. Mark, Cullen, Louise A. and Than, Martin P. (2018). Validity of a novel point-of-care troponin assay for single-test rule-out of acute myocardial infarction. JAMA Cardiology, 3 (11), 1108-1112. doi: 10.1001/jamacardio.2018.3368

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC

Prospective validation of prognostic and diagnostic syncope scores in the emergency department

du Fay de Lavallaz, Jeanne, Badertscher, Patrick, Nestelberger, Thomas, Isenrich, Rahel, Miró, Òscar, Salgado, Emilio, Geigy, Nicolas, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Bustamante Mandrión, José, Di Somma, Salvatore, Peacock, W. Frank, Kawecki, Damian, Boeddinghaus, Jasper, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, Strebel, Ivo, Keller, Dagmar I., Poepping, Imke, Kühne, Michael, Mueller, Christian, Reichlin, Tobias, Giménez, Maria Rubini, Walter, Joan, Kozhuharov, Nikola, Shrestha, Samyut ... For the BASEL IX Investigators (2018). Prospective validation of prognostic and diagnostic syncope scores in the emergency department. International Journal of Cardiology, 269, 114-121. doi: 10.1016/j.ijcard.2018.06.088

Circadian, weekly, seasonal, and temperature-dependent patterns of syncope aetiology in patients at increased risk of cardiac syncope

du Fay de Lavallaz, Jeanne, Badertscher, Patrick, Nestelberger, Thomas, Flores, Dayana, Miró, Òscar, Salgado, Emilio, Geigy, Nicolas, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Rodriguez-Adrada, Esther, Di Somma, Salvatore, Peacock, W. Frank, Kawecki, Damian, Boeddinghaus, Jasper, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, Strebel, Ivo, Keller, Dagmar I., Poepping, Imke, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, Giménez, Maria Rubini, Walter, Joan, Kozhuharov, Nikola, Shrestha, Samyut ... BASEL IX Investigators (2018). Circadian, weekly, seasonal, and temperature-dependent patterns of syncope aetiology in patients at increased risk of cardiac syncope. EP Europace, 21 (3), 511-521. doi: 10.1093/europace/euy186

Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department

Kavsak, Peter A., Neumann, Johannes T., Cullen, Louise, Than, Martin, Shortt, Colleen, Greenslade, Jaimi H., Pickering, John W., Ojeda, Francisco, Ma, Jinhui, Clayton, Natasha, Sherbino, Jonathan, Hill, Stephen A., McQueen, Matthew, Westermann, Dirk, Sörensen, Nils A., Parsonage, William A., Griffith, Lauren, Mehta, Shamir R., Devereaux, P.J., Richards, Mark, Troughton, Richard, Pemberton, Chris, Aldous, Sally, Blankenberg, Stefan and Worster, Andrew (2018). Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department. Canadian Medical Association Journal, 190 (33), E974-E984. doi: 10.1503/cmaj.180144

Deliberate clinical inertia: using meta-cognition to improve decision-making

Keijzers, Gerben, Fatovich, Daniel M., Egerton-Warburton, Diana, Cullen, Louise, Scott, Ian A., Glasziou, Paul and Croskerry, Pat (2018). Deliberate clinical inertia: using meta-cognition to improve decision-making. Emergency Medicine Australasia, 30 (4), 585-590. doi: 10.1111/1742-6723.13126

Re: Medical student enquiries on the art of clinical inertia

Keijzers, Gerben, Cullen, Louise, Egerton-Warburton, Diana and Fatovich, Daniel M (2018). Re: Medical student enquiries on the art of clinical inertia. EMA - Emergency Medicine Australasia, 30 (3), 435-436. doi: 10.1111/1742-6723.12980

‘What the hell is water?’ How to use deliberate clinical inertia in common emergency department situations

Egerton‐Warburton, Diana, Cullen, Louise, Keijzers, Gerben and Fatovich, Daniel M. (2018). ‘What the hell is water?’ How to use deliberate clinical inertia in common emergency department situations. Emergency Medicine Australasia, 30 (3), 426-430. doi: 10.1111/1742-6723.12950

Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: an observational study

Than, Martin P., Aldous, Sally J., Troughton, Richard W., Pemberton, Christopher J., Richards, A. Mark, Frampton, Christopher M. A., Florkowski, Christopher M., George, Peter M., Bailey, Samantha, Young, Joanna M., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William A., Everett, Brendan M., Peacock, W. Frank, Jaffe, Allan S. and Pickering, John W. (2018). Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: an observational study. Clinical Chemistry, 64 (7), 1044-1053. doi: 10.1373/clinchem.2017.285700

The assessment and management of chest pain in primary care: 'a focus on acute coronary syndrome'

Thomsett, Richard and Cullen, Louise (2018). The assessment and management of chest pain in primary care: 'a focus on acute coronary syndrome'. Australian Journal of General Practice, 47 (5), 246-251. doi: 10.31128/AFP-08-17-4304

A critical evaluation of the Beckman Coulter Access hsTnI: analytical performance, reference interval and concordance

Pretorius, Carel J., Tate, Jillian R., Wilgen, Urs, Cullen, Louise and Ungerer, Jacobus P. J. (2018). A critical evaluation of the Beckman Coulter Access hsTnI: analytical performance, reference interval and concordance. Clinical Biochemistry, 55, 49-55. doi: 10.1016/j.clinbiochem.2018.03.003

Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction

van der Linden, Noreen, Wildi, Karin, Twerenbold, Raphael, Pickering, John W, Than, Martin, Cullen, Louise, Greenslade, Jaimi, Parsonage, William, Nestelberger, Thomas, Boeddinghaus, Jasper, Badertscher, Patrick, Rubini Giménez, Maria, Klinkenberg, Lieke J J, Bekers, Otto, Schöni, Aline, Keller, Dagmar I, Sabti, Zaid, Puelacher, Christian, Cupa, Janosch, Schumacher, Lukas, Kozhuharov, Nikola, Grimm, Karin, Shrestha, Samyut, Flores, Dayana, Freese, Michael, Stelzig, Claudia, Strebel, Ivo, Miró, Òscar, Rentsch, Katharina ... Mueller, Christian (2018). Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction. Circulation, 138 (10), CIRCULATIONAHA.117.032003-999. doi: 10.1161/CIRCULATIONAHA.117.032003

Don't just do something, stand there! The value and art of deliberate clinical inertia

Keijzers, Gerben, Cullen, Louise, Egerton-Warburton, Diana and Fatovich, Daniel M (2018). Don't just do something, stand there! The value and art of deliberate clinical inertia. Emergency medicine Australasia : EMA, 30 (2), 273-278. doi: 10.1111/1742-6723.12922

Characteristics and occurrence of type 2 myocardial infarction in emergency department patients: a prospective study

Greenslade, Jaimi H., Adikari, Thushani, Mueller, Christian, Sandoval, Yader, Nestelberger, Thomas, Parsonage, William, Hawkins, Tracey and Cullen, Louise (2018). Characteristics and occurrence of type 2 myocardial infarction in emergency department patients: a prospective study. Emergency Medicine Journal : EMJ, 35 (3), 169-175. doi: 10.1136/emermed-2017-206869

Developing a value proposition for high-sensitivity troponin testing

St John, Andrew, Cullen, Louise, Jülicher, Paul and Price, Christopher P. (2018). Developing a value proposition for high-sensitivity troponin testing. Clinica Chimica Acta, 477, 154-159. doi: 10.1016/j.cca.2017.12.007

Evaluating rapid rule-out of acute myocardial infarction by use of a high-sensitivity cardiac troponin I assay at presentation

Greenslade, Jaimi, Cho, Elizabeth, Van Hise, Christopher, Hawkins, Tracey, Parsonage, William, Ungerer, Jacobus, Tate, Jillian, Pretorius, Carel, Than, Martin and Cullen, Louise (2018). Evaluating rapid rule-out of acute myocardial infarction by use of a high-sensitivity cardiac troponin I assay at presentation. Clinical Chemistry, 64 (5), 820-829. doi: 10.1373/clinchem.2017.283887

Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department

Greenslade, Jaimi H., Chung, Kimberly, Parsonage, William A., Hawkins, Tracey, Than, Martin, Pickering, John W. and Cullen, Louise (2018). Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department. Emergency Medicine Australasia : EMA, 30 (1), 47-54. doi: 10.1111/1742-6723.12913

ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway

Than, Martin P., Pickering, John W., Dryden, Jeremy M., Lord, Sally J., Aitken, S. Andrew, Aldous, Sally J., Allan, Kate E., Ardagh, Michael W., Bonning, John W. N., Callender, Rosie, Chapman, Laura R. E., Christiansen, Jonathan P., Cromhout, Andre P. J., Cullen, Louise, Deely, Joanne M., Devlin, Gerard P., Ferrier, Katherine A., Florkowski, Christopher M., Frampton, Christopher M. A., George, Peter M., Hamilton, Gregory J., Jaffe, Allan S., Kerr, Andrew J., Larkin, G. Luke, Makower, Richard M., Matthews, Timothy J. E., Parsonage, William A., Peacock, W. Frank, Peckler, Bradley F. ... Yates, Kim M. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway. Circulation, 137 (4), 354-363. doi: 10.1161/CIRCULATIONAHA.117.031984

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904

Indications and practical approach to non-invasive ventilation in acute heart failure

Masip, Josep, Frank Peacock, W., Price, Susanna, Cullen, Louise, Javier Martin-Sanchez, F., Seferovic, Petar, Maisel, Alan S., Miro, Oscar, Filippatos, Gerasimos, Vrints, Christiaan, Christ, Michael, Cowie, Martin, Platz, Elke, McMurray, John, DiSomma, Salvatore, Zeymer, Uwe, Bueno, Hector, Gale, Chris P., Lettino, Maddalena, Tavares, Mucio, Ruschitzka, Frank, Mebazaa, Alexandre, Harjola, Veli-Pekka and Mueller, Christian (2018). Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39 (1), 17-25. doi: 10.1093/eurheartj/ehx580

Prohormones in the early diagnosis of cardiac syncope

Badertscher, Patrick, Nestelberger, Thomas, de Lavallaz, Jeanne du Fay, Than, Martin, Morawiec, Beata, Kawecki, Damian, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Bustamante, José, Geigy, Nicolas, Christ, Michael, Di Somma, Salvatore, Peacock, W. Frank, Cullen, Louise, Sarasin, François, Flores, Dayana, Tschuck, Michael, Boeddinghaus, Jasper, Twerenbold, Raphael, Wildi, Karin, Sabti, Zaid, Puelacher, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola, Shrestha, Samyut, Strebel, Ivo, Rentsch, Katharina, Keller, Dagmar I. ... Mueller, Christian (2017). Prohormones in the early diagnosis of cardiac syncope. Journal of the American Heart Association, 6 (12) e006592. doi: 10.1161/JAHA.117.006592

Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome

Greenslade, Jaimi H., Carlton, Edward W., Van Hise, Christopher, Cho, Elizabeth, Hawkins, Tracey, Parsonage, William A., Tate, Jillian, Ungerer, Jacobus and Cullen, Louise (2017). Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome. Annals of Emergency Medicine, 71 (4), 439-451.e3. doi: 10.1016/j.annemergmed.2017.10.030

Diving into research: a practical guide for emergency medicine trainees

Cullen, Louise and Brown, Nathan (2017). Diving into research: a practical guide for emergency medicine trainees. Emergency Medicine Australasia : EMA, 29 (6), 722-723. doi: 10.1111/1742-6723.12891

Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome

Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter A., Blankenberg, Stefan, Neumann, Johannes, Söerensen, Nils A., Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J. E., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Ferry, Amy, Sandeman, Dennis, Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward ... Mills, Nicholas L. (2017). Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA - Journal of the American Medical Association, 318 (19), 1913-1924. doi: 10.1001/jama.2017.17488

Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study

Hawkins, Tracey, Greenslade, Jaimi H., Suna, Jessica, Williams, Julian, Jensen, Matthew, Donohue, Maria, Ho, Elizabeth, Van Hise, Christopher, Egerton-Warburton, Diana and Cullen, Louise (2017). Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study. Academic Emergency Medicine , 25 (1), 26-32. doi: 10.1111/acem.13335

A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department

Pickering, John W., Flaws, Dylan, Smith, Stephen W., Greenslade, Jaimi, Cullen, Louise, Parsonage, William, Carlton, Edward, Mark Richards, A., Troughton, Richard, Pemberton, Christopher, George, Peter M. and Than, Martin P. (2017). A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department. Academic Emergency Medicine, 25 (4), 434-443. doi: 10.1111/acem.13343

External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction

Van Hise, Christopher B., Greenslade, Jaimi H., Parsonage, William, Than, Martin, Young, Joanna and Cullen, Louise (2017). External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction. Clinical Biochemistry, 52, 161-163. doi: 10.1016/j.clinbiochem.2017.10.001

Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy

Carlton, Edward Watts, Pickering, John William, Greenslade, Jaimi, Cullen, Louise, Than, Martin, Kendall, Jason, Body, Richard, Parsonage, William A., Khattab, Ahmed and Greaves, Kim (2017). Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy. Heart (British Cardiac Society), 104 (8), 665-672. doi: 10.1136/heartjnl-2017-311983

Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016)

Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E. G. (2017). Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016). Heart Lung and Circulation, 26 (10), 1117-1117. doi: 10.1016/j.hlc.2017.08.004

Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study

Etaher, Aisha, Chew, Derek, Redfern, Julie, Briffa, Tom, Ellis, Chris, Hammett, Christopher, Lefkovits, Jeffrey, Elliott, John, Cullen, Louise, Brieger, David and French, John K. (2017). Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study. Heart, Lung and Circulation, 26 (10), 1051-1058. doi: 10.1016/j.hlc.2016.11.018

Implementing change: evaluating the Accelerated Chest pain Risk Evaluation (ACRE) project

Parsonage, William A., Milburn, Tanya, Ashover, Sarah, Skoien, Wade, Greenslade, Jaimi H., McCormack, Louise and Cullen, Louise (2017). Implementing change: evaluating the Accelerated Chest pain Risk Evaluation (ACRE) project. Medical Journal of Australia, 207 (5), 201-205. doi: 10.5694/mja16.01479

Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes

Cullen, Louise, Greenslade, Jaimi H., Hawkins, Tracey, Hammett, Chris, O'Kane, Shanen, Ryan, Kimberley, Parker, Kate, Schluter, Jessica, Dalton, Emily, Brown, Anthony F. T., Than, Martin, Peacock, W. Frank, Jaffe, Allan, O'Rourke, Peter K. and Parsonage, William A. (2017). Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes. Medical Journal of Australia, 207 (5), 195-200. doi: 10.5694/mja16.01351

A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study

Papendick, Cynthia, Blyth, Andrew, Seshadri, A., Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise, Quinn, Stephen, Karnon, Jon, Chuang, Anthony, Nelson, Adam J., Horsfall, Matthew, Morton, Erin and Chew, Derek P. (2017). A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study. American Heart Journal, 190, 25-33. doi: 10.1016/j.ahj.2017.05.004

Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain

Greenslade, Jaimi H., Nayer, Robert, Parsonage, William, Doig, Shaela, Young, Joanna, Pickering, John W., Than, Martin, Hammett, Christopher and Cullen, Louise (2017). Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain. Emergency Medicine Journal, 34 (8), 517-523. doi: 10.1136/emermed-2016-206366

Comparing the no objective testing rule to the HEART pathway

Greenslade, Jaimi and Cullen, Louise (2017). Comparing the no objective testing rule to the HEART pathway. Academic Emergency Medicine, 24 (9), 1169-1170. doi: 10.1111/acem.13240

Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm

Wildi, Karin, Cullen, Louise, Twerenbold, Raphael, Greenslade, Jaimi H., Parsonage, William, Boeddinghaus, Jasper, Nestelberger, Thomas, Sabti, Zaid, Rubini-Gimenez, Maria, Puelacher, Christian, Cupa, Janosch, Schumacher, Lukas, Badertscher, Patrick, Grimm, Karin, Kozhuharov, Nikola, Stelzig, Claudia, Freese, Michael, Rentsch, Katharina, Lohrmann, Jens, Kloos, Wanda, Buser, Andreas, Reichlin, Tobias, Pickering, John W., Than, Martin and Mueller, Christian (2017). Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm. Clinical Chemistry, 63 (7), 1227-1236. doi: 10.1373/clinchem.2016.268359

The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis

Jülicher, Paul, Greenslade, Jaimi H, Parsonage, William A and Cullen, Louise (2017). The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis. BMJ Open, 7 (6) e013653. doi: 10.1136/bmjopen-2016-013653

Rational clinical evaluation of suspected acute coronary syndromes: The value of more information

Hancock, David G., Chuang, Ming-Yu Anthony, Bystrom, Rebecca, Halabi, Amera, Jones, Rachel, Horsfall, Matthew, Cullen, Louise, Parsonage, William A. and Chew, Derek P. (2017). Rational clinical evaluation of suspected acute coronary syndromes: The value of more information. Emergency Medicine Australasia, 29 (6), 664-671. doi: 10.1111/1742-6723.12819

European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department

Miro, Oscar, Peacock, Frank W., McMurray, John J., Bueno, Hector, Christ, Michael, Maisel, Alan S., Cullen, Louise, Cowie, Martin R., Di Somma, Salvatore, Martin Sanchez, Francisco J., Platz, Elke, Masip, Josep, Zeymer, Uwe, Vrints, Christiaan, Price, Susanna, Mebazaa, Alexander and Mueller, Christian (2017). European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department. European Heart Journal-Acute Cardiovascular Care, 6 (4), 311-320. doi: 10.1177/2048872616633853

Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis

Pickering, John W., Than, Martin P., Cullen, Louise, Aldous, Sally, Ter Avest, Ewoud, Body, Richard, Carlton, Edward W., Collinson, Paul, Dupuy, Anne Marie, Ekelund, Ulf, Eggers, Kai M., Florkowski, Christopher M., Freund, Yonathan, George, Peter, Goodacre, Steve, Greenslade, Jaimi H., Jaffe, Allan S., Lord, Sarah J., Mokhtari, Arash, Mueller, Christian, Munro, Andrew, Mustapha, Sebbane, Parsonage, William, Peacock, W. Frank, Pemberton, Christopher, Richards, A. Mark, Sanchis, Juan, Staub, Lukas P., Troughton, Richard ... Young, Joanna (2017). Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis. Annals of Internal Medicine, 166 (10), 715-724. doi: 10.7326/M16-2562

Echocardiography and lung ultrasonography for the assessment and management of acute heart failure

Price, Susanna, for the Acute Heart Failure Study Group of the European Society of Cardiology Acute Cardiovascular Care Association, Platz, Elke, Cullen, Louise, Tavazzi, Guido, Christ, Michael, Cowie, Martin R., Maisel, Alan S., Masip, Josep, Miro, Oscar, McMurray, John J., Peacock, W. Frank, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Bueno, Hector, Zeymer, Uwe and Mueller, Christian (2017). Echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nature Reviews Cardiology, 14 (7), 427-440. doi: 10.1038/nrcardio.2017.56

Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction"

Than, Martin P., Pickering, John W., Cullen, Louise and Kavsak, Peter A. (2017). Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction". Circulation, 135 (16), e923-e924. doi: 10.1161/CIRCULATIONAHA.117.027479

Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI

Tan, Jack Wei Chieh, Lam, Carolyn S. P., Kasim, Sazzli Shahlan, Aw, Tar Choon, Abanilla, Joel M., Chang, Wei-Ting, Dang, Van Phuoc, Iboleon-Dy, Maria, Mumpuni, Sari Sri, Phommintikul, Arintaya, Ta, Manh Cuong, Topipat, Punkiat, Yiu, Kai Hang and Cullen, Louise (2017). Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI. Heart Asia, 9 (1) e000357, 81-87. doi: 10.1136/heartasia-2016-010818

Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study

Lavery, Tim, Greenslade, Jaimi H., Parsonage, William A., Hawkins, Tracey, Dalton, Emily, Hammett, Christopher and Cullen, Louise (2017). Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study. Emergency Medicine Australasia, 29 (2), 210-216. doi: 10.1111/1742-6723.12735

The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain

Knowlman, Thomas, Greenslade, Jaimi H., Parsonage, William, Hawkins, Tracey, Ruane, Lorcan, Martin, Paul, Prasad, Sandhir, Lancini, Daniel and Cullen, Louise (2017). The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain. Academic Emergency Medicine, 24 (3), 344-352. doi: 10.1111/acem.13123

The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol

Huis in ’t Veld, Maite Anna, Cullen, Louise, Mahler, Simon A., Backus, Barbra E., Dezman, Zachary D.W. and Mattu, Amal (2017). The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol. Western Journal of Emergency Medicine, 18 (3), 474-478. doi: 10.5811/westjem.2016.12.32676

Differences in presentation, management and outcomes in women and men presenting to an emergency department with possible cardiac chest pain

Ruane, Lorcan, Greenslade, Jaime H., Parsonage, William, Hawkins, Tracey, Hammett, Christopher, Lam, Carolyn S. P., Knowlman, Thomas, Doig, Shaela and Cullen, Louise (2017). Differences in presentation, management and outcomes in women and men presenting to an emergency department with possible cardiac chest pain. Heart, Lung and Circulation, 26 (12), 1282-1290. doi: 10.1016/j.hlc.2017.01.003

Panic Disorder in Patients Presenting to the Emergency Department With Chest Pain: Prevalence and Presenting Symptoms

Greenslade, Jaimi H., Hawkins, Tracey, Parsonage, William and Cullen, Louise (2017). Panic Disorder in Patients Presenting to the Emergency Department With Chest Pain: Prevalence and Presenting Symptoms. Heart, lung & circulation, 26 (12), 1310-1316. doi: 10.1016/j.hlc.2017.01.001

Appropriate use of high-sensitivity cardiac troponin levels in patients with suspected acute myocardial infarction- reply

Carlton, Edward, Cullen, Louise and Body, Richard (2017). Appropriate use of high-sensitivity cardiac troponin levels in patients with suspected acute myocardial infarction- reply. JAMA Cardiology, 2 (2), 229-230. doi: 10.1001/jamacardio.2016.4256

European Society of Cardiology - Acute Cardiovascular Care Association position paper on acute heart failure: a call for interdisciplinary care

Mueller, Christian, Christ, Michael, Cowie, Martin, Cullen, Louise, Maisel, Alan S., Masip, Josep, Miro, Oscar, McMurray, John, Peacock, Frank W., Price, Susanna, DiSomma, Salvatore, Bueno, Hector, Zeymer, Uwe, Mebazaa, Alexandre and Acute Heart Failure Study Group of the ESC Acute Cardiovascular Care Association (2017). European Society of Cardiology - Acute Cardiovascular Care Association position paper on acute heart failure: a call for interdisciplinary care. European Heart Journal: Acute Cardiovascular Care, 6 (1), 81-86. doi: 10.1177/2048872615593279

Heart failure in patients presenting with dyspnoea to the emergency department in the Asia Pacific region: an observational study

Keijzers, Gerben, Kelly, Anne-Maree, Cullen, Louise, Klim, Sharon, Graham, Colin A., Craig, Simon, Kuan, Win Sen, Jones, Peter, Holdgate, Anna, Lawoko, Charles and Laribi, Said (2017). Heart failure in patients presenting with dyspnoea to the emergency department in the Asia Pacific region: an observational study. BMJ Open, 7 (2) e013812, e013812. doi: 10.1136/bmjopen-2016-013812

Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics

Apple, Fred S., Cullen, Louise, Felker, G. Michael, Ginsburg, Geoffrey and Morrow, David (2017). Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics. Clinical Chemistry, 63 (1), 1-4. doi: 10.1373/clinchem.2016.263350

Early Rule-Out and Rule-In Strategies for Myocardial Infarction

Cullen, Louise A., Mills, Nicholas L., Mahler, Simon and Body, Richard (2017). Early Rule-Out and Rule-In Strategies for Myocardial Infarction. Clinical Chemistry, 63 (1), 129-139. doi: 10.1373/clinchem.2016.254730

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I

Neumann, Johannes Tobias, Sörensen, Nils Arne, Ojeda, Francisco, Schwemer, Tjark, Lehmacher, Jonas, Gönner, Saskia, Jarsetz, Nikolas, Keller, Till, Schaefer, Sarina, Renné, Thomas, Landmesser, Ulf, Clemmensen, Peter, Makarova, Nataliya, Schnabel, Renate B., Zeller, Tanja, Karakas, Mahir, Pickering, John W., Than, Martin, Parsonage, William, Greenslade, Jaimi, Cullen, Louise, Westermann, Dirk and Blankenberg, Stefan (2017). Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I. Clinical Chemistry, 63 (1), 394-402. doi: 10.1373/clinchem.2016.262659

Point: The Use of Sex-Specific Cutpoints for High-Sensitivity Cardiac Troponin Assays

Cullen, Louise A. and Mills, Nicholas L. (2017). Point: The Use of Sex-Specific Cutpoints for High-Sensitivity Cardiac Troponin Assays. Clinical Chemistry, 63 (1), 261-263. doi: 10.1373/clinchem.2016.254672

Does uric acid level provide additional risk stratification information in emergency patients with symptoms of possible acute coronary syndrome?

Jin, Harry, Greenslade, Jaimi H., Parsonage, William A., Hawkins, Tracey, Than, Martin and Cullen, Louise (2016). Does uric acid level provide additional risk stratification information in emergency patients with symptoms of possible acute coronary syndrome?. Critical Pathways in Cardiology, 15 (4), 169-173. doi: 10.1097/HPC.0000000000000092

Assessment of the European society of cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction

Pickering, John W., Greenslade, Jaimi H., Cullen, Louise, Flaws, Dylan, Parsonage, William, Aldous, Sally, George, Peter, Worster, Andrew, Kavsak, Peter A. and Than, Martin P. (2016). Assessment of the European society of cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction. Circulation, 134 (20), 1532-1541. doi: 10.1161/CIRCULATIONAHA.116.022677

Practical approach on frail older patients attended for acute heart failure

Martin-Sanchez, Francisco J., Christ, Michael, Miro, Òscar, Peacock, W. Frank, McMurray, John J., Bueno, Héctor, Maisel, Alan S., Cullen, Louise, Cowie, Martin R., Di Somma, Salvatore, Platz, Elke, Masip, Josep, Zeymer, Uwe, Vrints, Christiaan, Price, Susanna and Mueller, Christian (2016). Practical approach on frail older patients attended for acute heart failure. International Journal of Cardiology, 222, 62-71. doi: 10.1016/j.ijcard.2016.07.151

Use of the Theoretical Domains Framework to evaluate factors driving successful implementation of the Accelerated Chest pain Risk Evaluation (ACRE) project

Skoien, Wade, Page, Katie, Parsonage, William, Ashover, Sarah, Milburn, Tanya and Cullen, Louise (2016). Use of the Theoretical Domains Framework to evaluate factors driving successful implementation of the Accelerated Chest pain Risk Evaluation (ACRE) project. Implementation Science, 11 (1) 136. doi: 10.1186/s13012-016-0500-9

Agreement between patient-reported and cardiology-adjudicated medical history in patients with possible ischemic chest pain: an observational study

Iliceto, Alessandro, Berndt, Sara Louise, Greenslade, Jaimi H., Parsonage, William A., Hammett, Christopher, Than, Martin, Hawkins, Tracey, Parker, Kate, O'Kane, Shannen and Cullen, Louise (2016). Agreement between patient-reported and cardiology-adjudicated medical history in patients with possible ischemic chest pain: an observational study. Critical Pathways in Cardiology, 15 (3), 121-125. doi: 10.1097/HPC.0000000000000082

External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP)

Flaws, Dylan, Than, Martin, Scheuermeyer, Frank Xavier, Christenson, James, Boychuk, Barbara, Greenslade, Jaimi H., Aldous, Sally, Hammett, Christopher J., Parsonage, William A., Deely, Joanne M., Pickering, John W. and Cullen, Louise (2016). External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emergency Medicine Journal, 33 (9), 618-625. doi: 10.1136/emermed-2015-205028

National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016

Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E.G. (2016). National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016. Heart Lung and Circulation, 25 (9), 895-951. doi: 10.1016/j.hlc.2016.06.789

Heart fatty acid binding protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction

Young, Joanna M., Pickering, John W., George, Peter M., Aldous, Sally J., Wallace, John, Frampton, Chris M., Troughton, Richard W., Richards, Mark A., Greenslade, Jaimi H., Cullen, Louise and Than, Martin P. (2016). Heart fatty acid binding protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction. BMC Emergency Medicine, 16 (1) 34, 34. doi: 10.1186/s12873-016-0089-y

Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests

Parsonage, W. A., Mueller, C., Greenslade, J. H., Wildi, K., Pickering, J., Than, M., Aldous, S., Boeddinghaus, J., Hammett, C. J., Hawkins, T., Nestelberger, T., Reichlin, T., Reidt, S., Rubin Gimenez, M., Tate, J. R., Twerenbold, R., Ungerer, J. P. and Cullen, L. (2016). Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests. Heart, 102 (16), 1279-86. doi: 10.1136/heartjnl-2016-309270

National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of acute coronary syndromes 2016

Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E. G. (2016). National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of acute coronary syndromes 2016. Medical Journal of Australia, 205 (3), 128-133. doi: 10.5694/mja16.00368

Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction

Pickering, John W., Greenslade, Jaimi H., Cullen, Louise, Flaws, Dylan, Parsonage, William, George, Peter, Worster, Andrew, Kavsak, Peter A. and Than, Martin P. (2016). Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction. Heart, 102 (16), 1270-1278. doi: 10.1136/heartjnl-2015-308505

Appropriate use of serum troponin testing in general practice: a narrative review

Aroney, Constantine N. and Cullen, Louise (2016). Appropriate use of serum troponin testing in general practice: a narrative review. Medical Journal of Australia, 205 (2), 91-94. doi: 10.5694/mja16.00263

Diagnosis of myocardial infarction using a high-sensitivity Troponin I 1-hour algorithm

Neumann, Johannes Tobias, Sörensen, Nils Arne, Schwemer, Tjark, Ojeda, Francisco, Bourry, Rafael, Sciacca, Vanessa, Schaefer, Sarina, Waldeyer, Christoph, Sinning, Christoph, Renné, Thomas, Than, Martin, Parsonage, William, Wildi, Karin, Makarova, Nataliya, Schnabel, Renate B., Landmesser, Ulf, Mueller, Christian, Cullen, Louise, Greenslade, Jaimi, Zeller, Tanja, Blankenberg, Stefan, Karakas, Mahir and Westermann, Dirk (2016). Diagnosis of myocardial infarction using a high-sensitivity Troponin I 1-hour algorithm. JAMA Cardiology, 1 (4), 397-404. doi: 10.1001/jamacardio.2016.0695

Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice

Than, Martin P., Pickering, John W., Aldous, Sally J., Cullen, Louise, Frampton, Christopher M.A., Peacock, W. Frank, Jaffe, Allan S., Goodacre, Steve W., Richards, A. Mark, Ardagh, Michael W., Deely, Joanne M., Florkowski, Chris M., George, Peter, Hamilton, Gregory J., Jardine, David L., Troughton, Richard W., van Wyk, Pieter, Young, Joanna M., Bannister, Laura and Lord, Sally J. (2016). Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice. Annals of Emergency Medicine, 68 (1), 93-102.e1. doi: 10.1016/j.annemergmed.2016.01.001

Evaluation of high-sensitivity cardiac troponin I levels in patients with suspected acute coronary syndrome

Carlton, Edward, Greenslade, Jaimi, Cullen, Louise, Body, Richard, Than, Martin, Pickering, John W., Aldous, Sally, Carley, Simon, Hammett, Christopher, Kendall, Jason, Keevil, Brian, Lord, Sarah, Parsonage, William and Greaves, Kim (2016). Evaluation of high-sensitivity cardiac troponin I levels in patients with suspected acute coronary syndrome. JAMA Cardiology, 1 (4), 405-412. doi: 10.1001/jamacardio.2016.1309

Outcome at 30 days for low-risk chest pain patients assessed using an accelerated diagnostic pathway in the emergency department : Clinical Outcome of an ADP for low Risk Chest Pain in ED

Meek, Robert, Braitberg, George, Cullen, Louise, Than, Martin, Graudins, Andis and Glynn, Deirdre (2016). Outcome at 30 days for low-risk chest pain patients assessed using an accelerated diagnostic pathway in the emergency department : Clinical Outcome of an ADP for low Risk Chest Pain in ED. Emergency Medicine Australasia, 28 (3), 279-286. doi: 10.1111/1742-6723.12570

Time to presentation and 12-month health outcomes in patients presenting to the emergency department with symptoms of possible acute coronary syndrome

Cullen, Louise, Greenslade, Jaimi H., Menzies, Louven, Leong, Ashley, Than, Martin, Pemberton, Christopher, Aldous, Sally, Pickering, John, Dalton, Emily, Crosling, Bianca, Foreman, Rachelle and Parsonage, William A. (2016). Time to presentation and 12-month health outcomes in patients presenting to the emergency department with symptoms of possible acute coronary syndrome. Emergency Medicine Journal, 33 (6), 390-395. doi: 10.1136/emermed-2015-204978

Relationship between physiological parameters and acute coronary syndrome in patients presenting to the emergency department with undifferentiated chest pain

Greenslade, Jaimi H., Beamish, Daniel, Parsonage, William, Hawkins, Tracey, Schluter, Jessica, Dalton, Emily, Parker, Kate, Than, Martin, Hammett, Christopher, Lamanna, Arvin and Cullen, Louise (2016). Relationship between physiological parameters and acute coronary syndrome in patients presenting to the emergency department with undifferentiated chest pain. Journal of Cardiovascular Nursing, 31 (3), 267-273. doi: 10.1097/JCN.0000000000000228

Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction by use of high-sensitivity cardiac troponin I

Boeddinghaus, Jasper, Reichlin, Tobias, Cullen, Louise, Greenslade, Jaimi H., Parsonage, William A., Hammett, Christopher, Pickering, John W., Hawkins, Tracey, Aldous, Sally, Twerenbold, Raphael, Wildi, Karin, Nestelberger, Thomas, Grimm, Karin, Rubini-Gimenez, Maria, Puelacher, Christian, Kern, Vera, Rentsch, Katharina, Than, Martin and Mueller, Christian (2016). Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction by use of high-sensitivity cardiac troponin I. Clinical Chemistry, 62 (3), 494-504. doi: 10.1373/clinchem.2015.249508

The predictive value of high sensitivity-troponin velocity within the first 6h of presentation for cardiac outcomes regardless of acute coronary syndrome diagnosis

Chuang, Anthony, Hancock, David G., Horsfall, Matthew, Alhammad, Nasser J., Zhou, Julia, Cullen, Louise, French, John and Chew, Derek P. (2016). The predictive value of high sensitivity-troponin velocity within the first 6h of presentation for cardiac outcomes regardless of acute coronary syndrome diagnosis. International Journal of Cardiology, 204, 106-111. doi: 10.1016/j.ijcard.2015.11.132

Change to costs and lengths of stay in the emergency department and the Brisbane protocol: an observational study

Cheng, Qinglu, Greenslade, Jaimi H., Parsonage, William A., Barnett, Adrian G., Merollini, Katharina, Graves, Nicholas, Peacock, W. Frank and Cullen, Louise (2016). Change to costs and lengths of stay in the emergency department and the Brisbane protocol: an observational study. BMJ Open, 6 (2) e009746, 1-11. doi: 10.1136/bmjopen-2015-009746

Sex-specific versus overall cut points for a high sensitivity troponin I assay in predicting 1-year outcomes in emergency patients presenting with chest pain

Cullen, Louise, Greenslade, Jaimi H., Carlton, Edward W., Than, Martin, Pickering, John W., Ho, Ariel, Greaves, Kim, Berndt, Sara L., Body, Richard, Ryan, Kimberley and Parsonagel, William A. (2016). Sex-specific versus overall cut points for a high sensitivity troponin I assay in predicting 1-year outcomes in emergency patients presenting with chest pain. Heart, 102 (2), 120-126. doi: 10.1136/heartjnl-2015-308506

Myocardial infarction: rapid ruling out in the emergency room

Cullen, Louise, Parsonage, William and Than, Martin (2015). Myocardial infarction: rapid ruling out in the emergency room. The Lancet, 386 (10012), 2449-2450. doi: 10.1016/s0140-6736(15)00449-3

The incremental value of stress testing in patients with acute chest pain beyond serial cardiac troponin testing

Aldous, Sally, Richards, A Mark, Cullen, Louise, Pickering, John W and Than, Martin (2015). The incremental value of stress testing in patients with acute chest pain beyond serial cardiac troponin testing. Emergency Medicine Journal, 33 (5), 319-324. doi: 10.1136/emermed-2015-204823

Factors associated with triage assignment of emergency department patients ultimately diagnosed with acute myocardial infarction

Ryan, Kimberley, Greenslade, Jaimi, Dalton, Emily, Chu, Kevin, Brown, Anthony F. T. and Cullen, Louise (2015). Factors associated with triage assignment of emergency department patients ultimately diagnosed with acute myocardial infarction. Australian Critical Care, 29 (1), 23-26. doi: 10.1016/j.aucc.2015.05.001

'Chest pain typicality' in suspected acute coronary syndromes and the impact of clinical experience

Carlton, Edward W., Than, Martin, Cullen, Louise, Khattab, Ahmed and Greaves, Kim (2015). 'Chest pain typicality' in suspected acute coronary syndromes and the impact of clinical experience. American Journal of Medicine, 128 (10), 1109-1116.e2. doi: 10.1016/j.amjmed.2015.04.012

A Clinical Decision Rule to Identify Emergency Department Patients at Low Risk for Acute Coronary Syndrome Who Do Not Need Objective Coronary Artery Disease Testing: The No Objective Testing Rule

Greenslade, Jaimi H., Parsonage, William, Than, Martin, Scott, Adam, Aldous, Sally, Pickering, John W., Hammett, Christopher J. and Cullen, Louise (2015). A Clinical Decision Rule to Identify Emergency Department Patients at Low Risk for Acute Coronary Syndrome Who Do Not Need Objective Coronary Artery Disease Testing: The No Objective Testing Rule. Annals of Emergency Medicine, 67 (4), 478-489.e2. doi: 10.1016/j.annemergmed.2015.08.006

The utility of presentation and 4-hour high sensitivity troponin I to rule-out acute myocardial infarction in the emergency department

Pickering, John W., Young, Joanna M., George, Peter, Aldous, Sally, Cullen, Louise, Greenslade, Jaimi H., Richards, A. Mark, Troughton, Richard, Ardagh, Michael, Frampton, Christopher M. and Than, Martin P. (2015). The utility of presentation and 4-hour high sensitivity troponin I to rule-out acute myocardial infarction in the emergency department. Clinical Biochemistry, 48 (18), 1219-1224. doi: 10.1016/j.clinbiochem.2015.07.033

High-Sensitivity Cardiac Troponin T Concentrations below the Limit of Detection to Exclude Acute Myocardial Infarction: A Prospective Evaluation

Body, Richard, Burrows, Gillian, Carley, Simon, Cullen, Louise, Than, Martin, Jaffe, Allan S and Lewis, Philip S (2015). High-Sensitivity Cardiac Troponin T Concentrations below the Limit of Detection to Exclude Acute Myocardial Infarction: A Prospective Evaluation. Clinical Chemistry, 61 (7), 983-989. doi: 10.1373/clinchem.2014.231530

Two-hour diagnostic algorithms for early assessment of patients with acute chest pain - Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile

Eggers, Kai M, Aldous, Sally, Greenslade, Jaimi H, Johnston, Nina, Lindahl, Bertil, Parsonage, William A, Pickering, John W, Than, Martin and Cullen, Louise (2015). Two-hour diagnostic algorithms for early assessment of patients with acute chest pain - Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile. Clinica Chimica Acta, 445, 19-24. doi: 10.1016/j.cca.2015.03.002

Cost and outcomes of assessing patients with chest pain in an Australian emergency department

Cullen, Louise, Greenslade, Jaimi, Merollini, Katharina, Graves, Nicholas, Hammett, Christopher J. K., Hawkins, Tracey, Than, Martin P., Brown, Anthony F. T., Huang, Christopher B., Panahi, Seyed E., Dalton, Emily and Parsonage, William A. (2015). Cost and outcomes of assessing patients with chest pain in an Australian emergency department. Medical Journal of Australia, 202 (8), 427-432. doi: 10.5694/mja14.00472

Utility of Routine Exercise Stress Testing among Intermediate Risk Chest Pain Patients Attending an Emergency Department

Greenslade, Jaimi H, Parsonage, William, Ho, Ariel, Scott, Adam, Dalton, Emily, Hammett, Christopher, Brown, Anthony F.T, Parker, Kate and Cullen, Louise (2015). Utility of Routine Exercise Stress Testing among Intermediate Risk Chest Pain Patients Attending an Emergency Department. Heart Lung and Circulation, 24 (9), 879-884. doi: 10.1016/j.hlc.2015.03.025

Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients

Meller, Bernadette, Cullen, Louise, Parsonage, William A., Greenslade, Jaimi H., Aldous, Sally, Reichlin, Tobias, Wildi, Karin, Twerenbold, Raphael, Jaeger, Cedric, Hillinger, Petra, Haaf, Philip, Puelacher, Christian, Kern, Vera, Rentsch, Katharina, Stallone, Fabio, Rubini Gimenez, Maria, Ballarino, Paola, Bassetti, Stefano, Walukiewicz, Astrid, Troughton, Richard, Pemberton, Christopher J., Richards, A. Mark, Chu, Kevin, Reid, Christopher M., Than, Martin and Mueller, Christian (2015). Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients. International Journal of Cardiology, 184 (1), 208-15. doi: 10.1016/j.ijcard.2015.02.006

Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T

Reichlin, Tobias, Cullen, Louise, Parsonage, William A., Greenslade, Jaimi, Twerenbold, Raphael, Moehring, Berit, Wildi, Karin, Mueller, Sandra, Zellweger, Christa, Mosimann, Tamina, Rubini Gimenez, Maria, Rentsch, Katharina, Osswald, Stefan and Muller, Christian (2015). Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. American Journal of Medicine, 128 (4), 369-379.e4. doi: 10.1016/j.amjmed.2014.10.032

Combining presentation high-sensitivity cardiac troponin I and glucose measurements to rule-out an acute myocardial infarction in patients presenting to emergency department with chest pain

Greenslade, J. H., Kavsak, P., Parsonage, W., Shortt, C., Than, M., Pickering, J. W., Aldous, S. and Cullen, L. (2015). Combining presentation high-sensitivity cardiac troponin I and glucose measurements to rule-out an acute myocardial infarction in patients presenting to emergency department with chest pain. Clinical Biochemistry, 48 (4-5), 288-291. doi: 10.1016/j.clinbiochem.2014.11.019

A novel diagnostic protocol to identify patients suitable for discharge after a single high-sensitivity troponin

Carlton, Edward W, Cullen, Louise, Than, Martin, Gamble, James, Khattab, Ahmed and Greaves, Kim (2015). A novel diagnostic protocol to identify patients suitable for discharge after a single high-sensitivity troponin. Heart, 101 (13), 1041-1046. doi: 10.1136/heartjnl-2014-307288

Admission glycaemia and its association with acute coronary syndrome in Emergency Department patients with chest pain

Gardner, Logan S, Nguyen-Pham, Sallyanne, Greenslade, Jaimi H, Parsonage, William, D'Emden, Michael, Than, Martin, Aldous, Sally, Brown, Anthony and Cullen, Louise (2015). Admission glycaemia and its association with acute coronary syndrome in Emergency Department patients with chest pain. Emergency Medicine Journal, 32 (8), 608-612. doi: 10.1136/emermed-2014-204046

Availability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry

Cullen, Louise, French, John K, Briffa, Tom G, Redfern, Julie, Hammett, Christopher J K, Brieger, David B, Parsonage, William A, Lefkovits, Jeffrey, Ellis, Chris, Astley, Carolyn, Howell, Tegwen Eleanor, Elliott, John M and Chew, Derek P B (2015). Availability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry. Medical Journal of Australia, 202 (1), 36-39. doi: 10.5694/mja13.00275

Comparison of new point-of-care troponin assay with high sensitivity troponin in diagnosing myocardial infarction

Aldous, Sally, Richards, A. Mark, George, Peter M., Cullen, Louise, Parsonage, William A., Flaws, Dylan, Florkowski, Christopher M., Troughton, Richard W., O'Sullivan, Jack W., Reid, Christopher M., Bannister, Laura and Than, Martin (2014). Comparison of new point-of-care troponin assay with high sensitivity troponin in diagnosing myocardial infarction. International Journal of Cardiology, 177 (1), 182-186. doi: 10.1016/j.ijcard.2014.09.026

Decision limits and the reporting of cardiac troponin: Meeting the needs of both the cardiologist and the ED physician

Hickman, Peter E., Lindahl, Bertil, Cullen, Louise, Koerbin, Gus, Tate, Jill and Potter, Julia M. (2014). Decision limits and the reporting of cardiac troponin: Meeting the needs of both the cardiologist and the ED physician. Critical Reviews in Clinical Laboratory Sciences, 52 (1), 28-44. doi: 10.3109/10408363.2014.972497

The promise of high‐sensitivity troponin testing

Chew, Derek P B and Cullen, Louise (2014). The promise of high‐sensitivity troponin testing. Medical Journal of Australia, 201 (3), 125-126. doi: 10.5694/mja14.00858

Undetectable hs-cTnT in the Emergency Department and Risk of Myocardial Infarction

Cullen, Louise, Than, Martin and Peacock, W. Frank (2014). Undetectable hs-cTnT in the Emergency Department and Risk of Myocardial Infarction. Journal of the American College of Cardiology, 64 (6), 632-633. doi: 10.1016/j.jacc.2014.04.061

Towards a consistent definition of a significant delta troponin with z-scores: a way out of chaos?

Pretorius, Carel J., Cullen, Louise, Parsonage, William A., Greenslade, Jaimi H., Tate, Jillian R., Wilgen, Urs and Ungerer, Jacobus P. J. (2014). Towards a consistent definition of a significant delta troponin with z-scores: a way out of chaos?. European Heart Journal: Acute Cardiovascular Care, 3 (2), 149-157. doi: 10.1177/2048872613517084

Use of Observed Within-Person Variation of Cardiac Troponin in Emergency Department Patients for Determination of Biological Variation and Percentage and Absolute Reference Change Values

Simpson, Aaron J, Potter, Julia M, Koerbin, Gus, Oakman, Carmen, Cullen, Louise, Wilkes, Garry J, Scanlan, Samuel L, Parsonage, William and Hickman, Peter E (2014). Use of Observed Within-Person Variation of Cardiac Troponin in Emergency Department Patients for Determination of Biological Variation and Percentage and Absolute Reference Change Values. Clinical Chemistry, 60 (6), 848-854. doi: 10.1373/clinchem.2013.219410

Limited utility of exercise stress testing in the evaluation of suspected acute coronary syndrome in patients aged less than 40 years with intermediate risk features

Scott, Adam C., Bilesky, Jennifer, Lamanna, Arvin, Cullen, Louise, Brown, Anthony F. T., Denaro, Charles and Parsonage, William (2014). Limited utility of exercise stress testing in the evaluation of suspected acute coronary syndrome in patients aged less than 40 years with intermediate risk features. EMA - Emergency Medicine Australasia, 26 (2), 170-176. doi: 10.1111/1742-6723.12222

In suspected ACS, a diagnostic protocol using hs-TnI identified patients at low cardiac risk at 30 days

Cullen, L. and Carpenter, Christopher R. (2014). In suspected ACS, a diagnostic protocol using hs-TnI identified patients at low cardiac risk at 30 days. Annals of Internal Medicine, 160 (6). doi: 10.7326/0003-4819-160-6-201403180-02013

Implementation of a chest pain management service improves patient care and reduces length of stay

Scott, Adam C., O'Dwyer, Kristina M., Cullen, Louise, Brown, Anthony, Denaro, Charles and Parsonage, William (2014). Implementation of a chest pain management service improves patient care and reduces length of stay. Critical Pathways in Cardiology, 13 (1), 9-13. doi: 10.1097/01.hpc.0000441082.64971.54

Development and validation of the Emergency Department assessment of chest pain score and 2h accelerated diagnostic protocol

Than, Martin, Flaws, Dylan, Sanders, Sharon, Doust, Jenny, Glasziou, Paul, Kline, Jeffery, Aldous, Sally, Troughton, Richard, Reid, Christopher, Parsonage, William A., Frampton, Christopher, Greenslade, Jaimi H., Deely, Joanne M., Hess, Erik, Sadiq, Amr Bin, Singleton, Rose, Shopland, Rosie, Vercoe, Laura, Woolhouse-Williams, Morgana, Ardagh, Michael, Bossuyt, Patrick, Bannister, Laura and Cullen, Louise (2014). Development and validation of the Emergency Department assessment of chest pain score and 2h accelerated diagnostic protocol. EMA - Emergency Medicine Australasia, 26 (1), 34-44. doi: 10.1111/1742-6723.12164

Effect of recalibration of the hs-TnT assay on diagnostic performance

Parsonage, William A., Tate, Jillian R., Greenslade, Jaimi H., Hammett, Christopher J., Ungerer, Jacobus P. J., Pretorius, Carel J., Brown, Anthony F. T. and Cullen, Louise (2014). Effect of recalibration of the hs-TnT assay on diagnostic performance. Clinical Chemistry and Laboratory Medicine, 52 (2), E25-E27. doi: 10.1515/cclm-2013-0490

The new Vancouver Chest Pain Rule using troponin as the only biomarker: an external validation study

Cullen, L., Greenslade, J.H., Than, M., Brown, A.F.T., Hammett, C.J., Lamanna, A., Flaws, D.F., Chu, K., Fowles, L.F. and Parsonage, W.A. (2014). The new Vancouver Chest Pain Rule using troponin as the only biomarker: an external validation study. American Journal of Emergency Medicine, 32 (2), 129-134. doi: 10.1016/j.ajem.2013.10.021

Validation of an accelerated high‐sensitivity troponin T assay protocol in an Australian cohort with chest pain

Parsonage, William A, Greenslade, Jaimi H, Hammett, Christopher J, Lamanna, Arvin, Tate, Jillian R, Ungerer, Jacobus P, Chu, Kevin, Than, Martin, Brown, Anthony F T and Cullen, Louise (2014). Validation of an accelerated high‐sensitivity troponin T assay protocol in an Australian cohort with chest pain. Medical Journal of Australia, 200 (3), 161-165. doi: 10.5694/mja13.10466

A 2-Hour Diagnostic Protocol for Possible Cardiac Chest Pain in the Emergency Department : A Randomized Clinical Trial

Than, Martin, Aldous, Sally, Lord, Sarah Jane, Goodacre, Stephen, Frampton, Christopher M. A., Troughton, Richard, George, Peter, Florkowski, Christopher Michael, Ardagh, Michael, Smyth, David, Jardine, David Lewis, Peacock, William Frank, Young, Joanna, Hamilton, Gregory, Deely, Joanne M., Cullen, Louise and Richards, A. Mark (2014). A 2-Hour Diagnostic Protocol for Possible Cardiac Chest Pain in the Emergency Department : A Randomized Clinical Trial. JAMA Internal Medicine, 174 (1), 51-58. doi: 10.1001/jamainternmed.2013.11362

Comparison of high sensitivity troponin T and I assays in the diagnosis of non-ST elevation acute myocardial infarction in emergency patients with chest pain

Cullen, L., Aldous, S., Than, M., Greenslade, J. H., Tate, J. R., George, P. M., Hammett, C. J., Richards, A. M., Ungerer, J. P. J., Troughton, R. W., Brown, A. F. T., Flaws, D. F., Lamanna, A., Pemberton, C. J., Florkowski, C., Pretorius, C. J., Chu, K. and Parsonage, W. A. (2014). Comparison of high sensitivity troponin T and I assays in the diagnosis of non-ST elevation acute myocardial infarction in emergency patients with chest pain. Clinical Biochemistry, 47 (6), 321-326. doi: 10.1016/j.clinbiochem.2013.11.019

Performance of Risk Stratification for Acute Coronary Syndrome with Two-hour Sensitive Troponin Assay Results

Cullen, L., Greenslade, J., Than, M., Tate, J., Ungerer, J. P. J., Pretorius, C., Hammett, C. J., Lamanna, A., Chu, K., Brown, A. F. T. and Parsonage, W. A. (2014). Performance of Risk Stratification for Acute Coronary Syndrome with Two-hour Sensitive Troponin Assay Results. Heart Lung and Circulation, 23 (5), 428-434. doi: 10.1016/j.hlc.2013.11.003

Acute assessment of possible cardiac chest pain

Cullen, L. and Parsonage, W. (2013). Acute assessment of possible cardiac chest pain. Medicine Today, 14 (12), 41-44.

Troponin testing: End of an era?

Peacock, W. Frank, Cullen, Louise, Mueller, Christian and Than, Martin (2013). Troponin testing: End of an era?. Clinical Biochemistry, 46 (16-17), 1627-1628. doi: 10.1016/j.clinbiochem.2013.10.008

Delta troponin for the early diagnosis of AMI in emergency patients with chest pain

Cullen, L., Parsonage, W. A., Greenslade, J., Lamanna, A., Hammett, C. J., Than, M., Tate, J., Kalinowski, L., Ungerer, J. P. J., Chu, K. and Brown, A. (2013). Delta troponin for the early diagnosis of AMI in emergency patients with chest pain. International Journal of Cardiology, 168 (3), 2602-2608. doi: 10.1016/j.ijcard.2013.03.044

Validation of High-Sensitivity Troponin I in a 2-Hour Diagnostic Strategy to Assess 30-Day Outcomes in Emergency Department Patients With Possible Acute Coronary Syndrome

Cullen, Louise, Mueller, Christian, Parsonage, William A., Wildi, Karin, Greenslade, Jaimi H., Twerenbold, Raphael, Aldous, Sally, Meller, Bernadette, Tate, Jillian R., Reichlin, Tobias, Hammett, Christopher J., Zellweger, Christa, Ungerer, Jacobus P. J., Gimenez, Maria Rubini, Troughton, Richard, Murray, Karsten, Brown, Anthony F. T., Mueller, Mira, George, Peter, Mosimann, Tamina, Flaws, Dylan F., Reiter, Miriam, Lamanna, Arvin, Haaf, Philip, Pemberton, Christopher J., Richards, A. Mark, Chu, Kevin, Reid, Christopher M., Peacock, William Frank ... Than, Martin (2013). Validation of High-Sensitivity Troponin I in a 2-Hour Diagnostic Strategy to Assess 30-Day Outcomes in Emergency Department Patients With Possible Acute Coronary Syndrome. Journal of the American College of Cardiology, 62 (14), 1242-1249. doi: 10.1016/j.jacc.2013.02.078

The HEART score for the assessment of patients with chest pain in the emergency department: A multinational validation study

Six, A.J., Cullen, L., Backus, B.E., Greenslade, J., Parsonage, W., Aldous, S., Doevendans, P.A. and Than, M. (2013). The HEART score for the assessment of patients with chest pain in the emergency department: A multinational validation study. Critical Pathways in Cardiology, 12 (3), 121-126. doi: 10.1097/HPC.0b013e31828b327e

Introduction of an accelerated diagnostic protocol in the assessment of emergency department patients with possible acute coronary syndrome: The Nambour Short Low-Intermediate Chest pain project

George, Terry, Ashover, Sarah, Cullen, Louise, Larsen, Peter, Gibson, Jason, Bilesky, Jennifer, Coverdale, Steven and Parsonage, William (2013). Introduction of an accelerated diagnostic protocol in the assessment of emergency department patients with possible acute coronary syndrome: The Nambour Short Low-Intermediate Chest pain project. Emergency Medicine Australasia, 25 (4), 340-344. doi: 10.1111/1742-6723.12091

The approach to patients with possible cardiac chest pain

Parsonage, W.A., Cullen, L. and Younger, J.F. (2013). The approach to patients with possible cardiac chest pain. Medical Journal of Australia, 199 (1), 30-34. doi: 10.5694/mja12.11171

Examining Renal Impairment as a Risk Factor for Acute Coronary Syndrome: A Prospective Observational Study

Greenslade, Jaimi H., Cullen, Louise, Kalinowski, Lauren, Parsonage, William, Palmer, Suetonia, Aldous, Sally, Richards, Mark, Chu, Kevin, Brown, Anthony F. T., Troughton, Richard, Pemberton, Chris and Than, Martin (2013). Examining Renal Impairment as a Risk Factor for Acute Coronary Syndrome: A Prospective Observational Study. Annals of Emergency Medicine, 62 (1), 38-46. doi: 10.1016/j.annemergmed.2013.01.011

Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study

Greenslade, Jaimi H., Cullen, Louise, Than, Martin, Aldous, Sally, Chu, Kevin, Brown, Anthony F. T., Richards, A. Mark, Pemberton, Christopher J., George, Peter and Parsonage, William A. (2013). Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study. American Journal of Emergency Medicine, 31 (7), 1103-1107. doi: 10.1016/j.ajem.2013.04.016

What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey

Than, Martin, Herbert, Mel, Flaws, Dylan, Cullen, Louise, Hess, Erik, Hollander, Judd E., Diercks, Deborah, Ardagh, Michael W., Kline, Jeffrey A., Munro, Zea and Jaffe, Allan (2013). What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey. International Journal of Cardiology, 166 (3), 752-754. doi: 10.1016/j.ijcard.2012.09.171

Cardiac Risk Stratification Scoring Systems for Suspected Acute Coronary Syndromes in the Emergency Department

Than, M. P., Flaws, D. F., Cullen, L. and Deely, J. M. (2013). Cardiac Risk Stratification Scoring Systems for Suspected Acute Coronary Syndromes in the Emergency Department. Current Emergency and Hospital Medicine Reports, 1 (1), 53-63. doi: 10.1007/s40138-012-0004-0

Comparison of three risk stratification rules for predicting patients with acute coronary syndrome presenting to an australian emergency department

Cullen, L., Greenslade, J., Hammett, C.J., Brown, A.F.T., Chew, D.P., Bilesky, J., Than, M., Lamanna, A., Ryan, K., Chu, K. and Parsonage, W.A. (2013). Comparison of three risk stratification rules for predicting patients with acute coronary syndrome presenting to an australian emergency department. Heart Lung and Circulation, 22 (10), 844-851. doi: 10.1016/j.hlc.2013.03.074

Comparison of early biomarker strategies with the Heart Foundation of Australia/Cardiac Society of Australia and New Zealand guidelines for risk stratification of ED patients with chest pain

Cullen, Louise, Parsonage, William A., Greenslade, Jaimi, Lamanna, Arvin, Hammett, Christopher J., Than, Martin, Ungerer, Jacobus P. J., Chu, Kevin, O'Kane, Shanen and Brown, Anthony F. T. (2012). Comparison of early biomarker strategies with the Heart Foundation of Australia/Cardiac Society of Australia and New Zealand guidelines for risk stratification of ED patients with chest pain. Emergency Medicine Australasia, 24 (6), 595-603. doi: 10.1111/1742-6723.12008

A 2-hour thrombolysis in myocardial infarction score outperforms other risk stratification tools in patients presenting with possible acute coronary syndromes: comparison of chest pain risk stratification tools

Aldous, Sally J., Richards, Mark, Cullen, Louise, Troughton, Richard and Than, Martin (2012). A 2-hour thrombolysis in myocardial infarction score outperforms other risk stratification tools in patients presenting with possible acute coronary syndromes: comparison of chest pain risk stratification tools. American Heart Journal, 164 (4), 516-523. doi: 10.1016/j.ahj.2012.06.025

Highly sensitive troponin assays - a two-edged sword?

Scott, Ian A., Cullen, Louise, Tate, Jillian R. and Parsonage, William (2012). Highly sensitive troponin assays - a two-edged sword?. Medical Journal of Australia, 197 (6), 320-323. doi: 10.5694/mja11.11199

2-hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: The ADAPT trial

Than, Martin, Cullen, Louise, Aldous, Sally, Parsonage, William A., Reid, Christopher M., Greenslade, Jaimi, Flaws, Dylan, Hammett, Christopher J., Beam, Daren M., Ardagh, Michael W., Troughton, Richard, Brown, Anthony F.T., George, Peter, Florkowski, Christopher M., Kline, Jeffrey A., Peacock, W. Frank, Maisel, Alan S., Lim, Swee Han, Lamanna, Arvin and Richards, A. Mark (2012). 2-hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: The ADAPT trial. Journal of the American College of Cardiology, 59 (23), 2091-2098. doi: 10.1016/j.jacc.2012.02.035

A new improved accelerated diagnostic protocol safely identifies low-risk patients with chest pain in the emergency department

Aldous, Sally J., Richards, Mark A., Cullen, Louise, Troughton, Richard and Than, Martin (2012). A new improved accelerated diagnostic protocol safely identifies low-risk patients with chest pain in the emergency department. Academic Emergency Medicine, 19 (5), 510-516. doi: 10.1111/j.1553-2712.2012.01352.x

Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain

Aldous, Sally J., Richards, Mark, Cullen, Louise, Troughton, Richard and Than, Martin (2012). Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain. Canadian Medical Association Journal, 184 (5), E260-E268. doi: 10.1503/cmaj.110773

Examining the signs and symptoms experienced by individuals with suspected acute coronary syndrome in the Asia-pacific region: A prospective observational study

Greenslade, Jaimi H., Cullen, Louise, Parsonage, William, Reid, Christopher M., Body, Richard, Richards, Mark, Hawkins, Tracey, Lim, Swee Han and Than, Martin (2012). Examining the signs and symptoms experienced by individuals with suspected acute coronary syndrome in the Asia-pacific region: A prospective observational study. Annals of Emergency Medicine, 60 (6), 777-785. doi: 10.1016/j.annemergmed.2012.05.008

In reply

Aldous, Sally J., Richards, A. Mark, Cullen, Louise and Than, Martin P. (2012). In reply. Clinical Chemistry, 58 (1), 313-314. doi: 10.1373/clinchem.2011.176305

The role of cardiac computed tomography in assessment of acute chest pain

Parsonage, W.A., Cullen, L., Younger, J.F. and Than, M. (2012). The role of cardiac computed tomography in assessment of acute chest pain. Heart, Lung and Circulation, 21 (11), 763-763. doi: 10.1016/j.hlc.2012.04.011

Early dynamic change in high-sensitivity cardiac troponin T in the investigation of acute myocardial infarction

Aldous, Sally J., Richards, A. Mark, Cullen, Louise and Than, Martin P. (2011). Early dynamic change in high-sensitivity cardiac troponin T in the investigation of acute myocardial infarction. Clinical Chemistry, 57 (8), 1154-1160. doi: 10.1373/clinchem.2010.161166

Troponin: A risk-defining biomarker for emergency department physicians

Cullen, Louise (2011). Troponin: A risk-defining biomarker for emergency department physicians. Emergency Medicine Australasia, 23 (4), 391-394. doi: 10.1111/j.1742-6723.2011.01458.x

The evolution of Chest pain pathways

Mangleson, Frances Iris Jean, Cullen, Louise and Scott, Adam Charles (2011). The evolution of Chest pain pathways. Critical Pathways in Cardiology, 10 (2), 69-75. doi: 10.1097/HPC.0b013e3182215b48

A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): A prospective observational validation study

Than, Martin, Cullen, Louise, Reid, Christopher M., Lim, Swee Han, Aldous, Sally, Ardagh, Michael W., Peacock, W. Frank, Parsonage, William A., Ko, Hiu Fai, Kasliwal, Ravi R., Bansal, Manish, Soerianata, Sunarya, Hu, Dayi, Ding, Rongjing, Hua, Qi, Seok-Min, Kang, Sritara, Piyamitr, Sae-Lee, Ratchanee, Chiu, Te-Fa, Tsai, Kuang-Chau, Chu, Fang-Yeh, Chen, Wei-Kung, Chang, Wen-Han, Flaws, Dylan F., George, Peter M. and Richards, A. Mark (2011). A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): A prospective observational validation study. The Lancet, 377 (9771), 1077-1084. doi: 10.1016/S0140-6736(11)60310-3

Authors' reply

Than, Martin, Cullen, Louise, Reid, Christopher M., Lim, Swee Han and Richards, Mark (2011). Authors' reply. The Lancet, 378 (9789), 398-399. doi: 10.1016/S0140-6736(11)61206-3

Future developments in chest pain diagnosis and management

Brown, Anthony F. T., Cullen, Louise and Than, Martin (2010). Future developments in chest pain diagnosis and management. Medical Clinics of North America, 94 (2), 375-400. doi: 10.1016/j.mcna.2010.01.010

Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia

Cullen, Louise, Than, Martin, Brown, Anthony F. T., Richards, Mark, Parsonage, William, Flaws, Dylan, Hollander, Judd E., Christenson, Robert H., Kline, Jeffrey A., Goodacre, Steven and Jaffe, Allan S. (2010). Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia. Emergency Medicine Australasia, 22 (1), 35-55. doi: 10.1111/j.1742-6723.2010.01256.x

Nebulized Lidocaine Decreases the Discomfort of Nasogastric Tube Insertion: a randomized, Double-blind Trial

Cullen, Louise, Taylor, David, Taylor, Simone and Chu, Kevin (2004). Nebulized Lidocaine Decreases the Discomfort of Nasogastric Tube Insertion: a randomized, Double-blind Trial. Annals of Emergency Medicine, 44 (2), 131-137. doi: 10.1016/j.annemergmed.2004.03.033

Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain in the emergency department

Sharma, Sweekriti, Traeger, Adrian, Tcharkhedian, Elise, Middleton, Paul, Cullen, Louise and Maher, Chris G. (2022). Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain in the emergency department. OXFORD: OXFORD UNIV PRESS.

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

Hoe, L. See, Shuker, T., Bartnikowski, N., Passmore, M., Bouquet, M., Obonyo, N., Engkilde-Pedersen, S., McDonald, C., Wells, M., Boon, A., Hyslop, K., James, L., Wildi, K., Cullen, L., Bassi, G. Li, Suen, J., McGiffin, D. and Fraser, J. (2019). Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model. 67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, Australia, 8-11 August 2019. chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2019.06.074

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116

Impact of routine implementation of high sensitivity troponin in a state-wide health service

Khan, E., Chuang, A., Halabi, A., Tiver, K., Horsfall, M., Briffa, T., Sun, B., Cullen, L., French, J. and Chew, D. (2018). Impact of routine implementation of high sensitivity troponin in a state-wide health service. European Society of Cardiology Congress, Munich, Germany, 25-29 August 2018. Oxford, United Kingdom: Oxford University Press.

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Positive predictive value of exercise electrocardiography in patients referred from a Brisbane Emergency Department with chest pain

Camuglia, A., Gibson, J., Hammett, C., Brown, A., Cullen, L. and Parsonage, W. (2010). Positive predictive value of exercise electrocardiography in patients referred from a Brisbane Emergency Department with chest pain. The Cardiac Society of Australia and New Zealand, Annual Scientific Meeting, Adelaide, SA, Australia, 5-8 August 2010. Chatswood, NSW, Australia: Elsevier Australia. doi: 10.1016/j.hlc.2010.06.742