The University of Queensland

Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers

Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A. and Thurecht, Kristofer J. (2023). Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers. Biomaterials, 302 122318, 1-18. doi: 10.1016/j.biomaterials.2023.122318

A salivary biomarker panel to detect liver cirrhosis

Trevisan França de Lima, Lucas, Crawford, Darrell H. G., Broszczak, Daniel A., Zhang, Xi, Bridle, Kim R. and Punyadeera, Chamindie (2023). A salivary biomarker panel to detect liver cirrhosis. iScience, 26 (7) 107015, 107015. doi: 10.1016/j.isci.2023.107015

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver

Crawford, Darrell H. G., Ramm, Grant A., Bridle, Kim R., Nicoll, Amanda J., Delatycki, Martin B. and Olynyk, John K. (2023). Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver. Hepatology International, 17 (3), 522-541. doi: 10.1007/s12072-023-10510-3

Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysis

Liu, Xin, Wang, Haolu, Liu, Xinyao, Bridle, Kim, Crawford, Darrell and Liang, Xiaowen (2022). Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysis. Pharmacology and Therapeutics, 237 108163, 108163. doi: 10.1016/j.pharmthera.2022.108163

Long-term survival and postoperative complications of pre-liver transplantation transarterial chemoembolisation in hepatocellular carcinoma: a systematic review and meta-analysis

Butcher, Daniel A., Brandis, Kelli J., Wang, Haolu, Spannenburg, Liam, Bridle, Kim R., Crawford, Darrell HG. and Liang, Xiaowen (2022). Long-term survival and postoperative complications of pre-liver transplantation transarterial chemoembolisation in hepatocellular carcinoma: a systematic review and meta-analysis. European Journal of Surgical Oncology, 48 (3), 621-631. doi: 10.1016/j.ejso.2021.09.017

CD73 and PD-L1 as potential therapeutic targets in gallbladder cancer

Cao, Lu, Bridle, Kim R., Shrestha, Ritu, Prithviraj, Prashanth, Crawford, Darrell H. G. and Jayachandran, Aparna (2022). CD73 and PD-L1 as potential therapeutic targets in gallbladder cancer. International Journal of Molecular Sciences, 23 (3) 1565, 1565. doi: 10.3390/ijms23031565

Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways

Crawford, Darrell H.G., Ross, Diana G.F., Jaskowski, Lesley-Anne, Burke, Leslie J., Britton, Laurence J., Musgrave, Nick, Briskey, David, Rishi, Gautam, Bridle, Kim R. and Subramaniam, V. Nathan (2021). Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (7) 166142, 166142. doi: 10.1016/j.bbadis.2021.166142

Dual targeting of sorafenib-resistant HCC-derived cancer stem cells

Shrestha, Ritu, Bridle, Kim R., Cao, Lu, Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Dual targeting of sorafenib-resistant HCC-derived cancer stem cells. Current Oncology, 28 (3), 2150-2172. doi: 10.3390/curroncol28030200

Prognostic role of immune checkpoint regulators in cholangiocarcinoma: a pilot study

Cao, Lu, Prithviraj, Prashanth, Shrestha, Ritu, Sharma, Revati, Anaka, Matthew, Bridle, Kim R., Kannourakis, George, Crawford, Darrell H.G. and Jayachandran, Aparna (2021). Prognostic role of immune checkpoint regulators in cholangiocarcinoma: a pilot study. Journal of Clinical Medicine, 10 (10) 2191, 2191. doi: 10.3390/jcm10102191

Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to sorafenib treatment

Shrestha, Ritu, Prithviraj, Prashanth, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to sorafenib treatment. Journal of Clinical Medicine, 10 (9) 1889, 1889. doi: 10.3390/jcm10091889

Inhibition of MLKL attenuates necroptotic cell death in a murine cell model of ischaemia injury

Baidya, Raji, Gautheron, Jérémie, Crawford, Darrell H. G., Wang, Haolu and Bridle, Kim R. (2021). Inhibition of MLKL attenuates necroptotic cell death in a murine cell model of ischaemia injury. Journal of Clinical Medicine, 10 (2) 212, 1-18. doi: 10.3390/jcm10020212

Immune checkpoint molecules are regulated by transforming growth factor (Tgf)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Immune checkpoint molecules are regulated by transforming growth factor (Tgf)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma. International Journal of Medical Sciences, 18 (12), 2466-2479. doi: 10.7150/ijms.54239

Assessment and transplantation of orphan donor livers: a back-to-base approach to normothermic machine perfusion

Reiling, Janske, Butler, Nick, Simpson, Andrew, Hodgkinson, Peter, Campbell, Catherine, Lockwood, David, Bridle, Kim, Santrampurwala, Nishreen, Britton, Laurence, Crawford, Darrell, Dejong, Cornelius H. C. and Fawcett, Jonathan (2020). Assessment and transplantation of orphan donor livers: a back-to-base approach to normothermic machine perfusion. Liver Transplantation, 26 (12), 1618-1628. doi: 10.1002/lt.25850

The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

Trevisan França de Lima, Lucas, Broszczak, Daniel, Zhang, Xi, Bridle, Kim, Crawford, Darrell and Punyadeera, Chamindie (2020). The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinoma. Biochimica et Biophysica Acta - Reviews on Cancer, 1874 (2) 188451, 188451. doi: 10.1016/j.bbcan.2020.188451

Necroptosis in hepatosteatotic ischaemia-reperfusion injury

Baidya, Raji, Crawford, Darrell H. G., Gautheron, Jérémie, Wang, Haolu and Bridle, Kim R. (2020). Necroptosis in hepatosteatotic ischaemia-reperfusion injury. International Journal of Molecular Sciences, 21 (16) 5931, 1-29. doi: 10.3390/ijms21165931

TNF-α-mediated epithelial-to-mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H.G. and Jayachandran, Aparna (2020). TNF-α-mediated epithelial-to-mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma. Molecular Medicine Reports, 21 (4), 1849-1860. doi: 10.3892/mmr.2020.10991

Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review

Jayachandran, Aparna, Shrestha, Ritu, Bridle, Kim R. and Crawford, Darrell H. G. (2020). Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review. Hepatoma Research, 6 8. doi: 10.20517/2394-5079.2019.35

Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma

Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun-Xia, Crawford, Darrell H. G., Roberts, Michael S. and Liang, Xiaowen (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147 (6) ijc.32899, 1519-1527. doi: 10.1002/ijc.32899

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900

Immune checkpoint blockade therapies for HCC: current status and future implications

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2019). Immune checkpoint blockade therapies for HCC: current status and future implications. Hepatoma Research, 2019 (5) 32. doi: 10.20517/2394-5079.2019.24

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

Núñez, Kelley G., Frank, Anderson, Gonzalez-Rosario, Janet, Galliano, Gretchen, Bridle, Kim, Crawford, Darrell, Seal, John, Abbruscato, Frank, Vashistha, Himanshu, Thevenot, Paul T. and Cohen, Ari J. (2019). Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury. PLoS One, 14 (4) e0216242, e0216242. doi: 10.1371/journal.pone.0216242

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

Huang, I-Tao, Dhungel, Bijay, Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna and Steel, Jason C (2019). Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma. Expert Opinion on Investigational Drugs, 28 (1), 7-18. doi: 10.1080/13543784.2019.1551359

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

Jayachandran, Aparna, Manda, Sasidhar Venkata, Shrestha, Ritu, Bridle, Kim R., Prithviraj, Prashanth and Crawford, Darrell H. G. (2018). Exosome-based liquid biopsy in the management of hepatocellular carcinoma. Hepatoma Research, 4 (8) 44, 44. doi: 10.20517/2394-5079.2018.59

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

Shrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R., Crawford, Darrell H. G., Dhungel, Bijay, Steel, Jason C. and Jayachandran, Aparna (2018). Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma. Frontiers in Oncology, 8 (JUL) 269, 269. doi: 10.3389/fonc.2018.00269

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

Britton, Laurence, Bridle, Kim, Reiling, Janske, Santrampurwala, Nishreen, Wockner, Leesa, Ching, Helena, Stuart, Katherine, Subramaniam, V Nathan, Jeffrey, Gary, St Pierre, Tim, House, Michael, Gummer, Joel, Trengove, Robert, Olynyk, John, Crawford, Darrell and Adams, Leon (2018). Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. Hepatology Communications, 2 (6), 644-653. doi: 10.1002/hep4.1190

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

Britton, Laurence, Jaskowski, Lesley-Anne, Bridle, Kim, Secondes, Eriza, Wallace, Daniel, Santrampurwala, Nishreen, Reiling, Janske, Miller, Gregory, Mangiafico, Salvatore, Andrikopoulos, Sofianos, Subramaniam, V. Nathan and Crawford, Darrell (2018). Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet. CMGH, 5 (3), 319-331. doi: 10.1016/j.jcmgh.2018.01.005

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, Kim, Jaskowski, Lesley-Anne, He, Jingjing, Ng, Choaping, Ruelcke, Jayde E., Mohamed, Ahmed, Reiling, Janske, Santrampurwala, Nishreen, Hill, Michelle M., Whitehead, Jonathan P., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2018). Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes. Cellular and Molecular Gastroenterology and Hepatology, 6 (2), 214-217. doi: 10.1016/j.jcmgh.2018.04.005

The Implications of the Shift Toward Donation After Circulatory Death in Australia

Reiling, Janske, Forrest, Elizabeth, Bridle, Kim R., Britton, Laurence J., Santrampurwala, Nishreen, Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2017). The Implications of the Shift Toward Donation After Circulatory Death in Australia. Transplantation Direct, 3 (12) e226, 1-7. doi: 10.1097/TXD.0000000000000743

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

Reiling, J., Bridle, K. R., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Jansen, P. L. M., Damink, S. W. M. O., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model. Biochimica et Biophysica Acta, 1864 (4 Pt B), 1284-1292. doi: 10.1016/j.bbadis.2017.06.028

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374, 45374. doi: 10.1038/srep45374

Contribution of liver nonparenchymal cells to hepatic fibrosis: interactions with the local microenvironment

Fausther, Michel, Pritchard, Michele T., Popov, Yury V. and Bridle, Kim (2017). Contribution of liver nonparenchymal cells to hepatic fibrosis: interactions with the local microenvironment. Biomed Research International, 2017 6824762, 6824762-4. doi: 10.1155/2017/6824762

Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model

Reiling, Janske, Bridle, Kim R., Gijbels, Marion, Schaap, Frank G., Jaskowski, Lesley, Santrampurwala, Nishreen, Britton, Laurence J., Campbell, Catherine M., Olde Damink, Steven W. M., Crawford, Darrell H. G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2017). Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model. Liver Transplantation, 23 (2), 194-206. doi: 10.1002/lt.24681

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

Britton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan and Crawford, Darrell (2016). Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiological Reports, 4 (12) e12837, e12837. doi: 10.14814/phy2.12837

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

Bridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494

Urea production during Normothermic Machine Perfusion: Price of Success?

Reiling, Janske, Lockwood, David S. R., Simpson, Andrew H., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell Henry G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2015). Urea production during Normothermic Machine Perfusion: Price of Success?. Liver Transplantation, 21 (5), 700-703. doi: 10.1002/lt.24094

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

Sobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720

Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging

Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780

Diagnostic imaging and therapeutic application of nanoparticles targeting the liver

Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 (6), 939-958. doi: 10.1039/C4TB01611D

Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Subramaniam,V. Nathan, Clouston, Andrew D., Crane, Denis I., Bridle, Kim R., Anderson, Gregory J. and Fletcher, Linda M. (2013). Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. Laboratory Investigation, 93 (12), 1295-1312. doi: 10.1038/labinvest.2013.121

Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic Pathways

Bridle, K.R, Popa, C, Morgan, ML, Sobbe, AL, Clouston, AD, Fletcher, LM and Crawford, DHG (2009). Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic Pathways. Liver Transplantation, 15 (10), 1315-1324. doi: 10.1002/lt.21804

Fibrogenesis in Pediatric Cholestatic Liver Disease: Role of Taurocholate and Hepatocyte-Derived Monocyte Chemotaxis Protein-1 in Hepatic Stellate Cell Recruitment

Ramm, GA, Shepherd, RW, Hoskins, AC, Greco, SA, Ney, AD, Pereira, TN, Bridle, Kim R., Doecke, JD, Meikle, PJ, Turlin, B and Lewindon, PJ (2009). Fibrogenesis in Pediatric Cholestatic Liver Disease: Role of Taurocholate and Hepatocyte-Derived Monocyte Chemotaxis Protein-1 in Hepatic Stellate Cell Recruitment. Hepatology, 49 (2), 533-544. doi: 10.1002/hep.22637

Hepcidin regulation in wild-type and Hfe knockout mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

Heritage, Mandy L., Murphy, Therese L., Bridle, Kim R., Anderson, Gregory J., Crawford, Darrell H. G. and Fletcher, Linda M. (2009). Hepcidin regulation in wild-type and Hfe knockout mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. Alcoholism, Clinical and Experimental Research, 33 (8), 1391-1400. doi: 10.1111/j.1530-0277.2009.00969.x

Effect of phorbol ester and platelet-derived growth factor on protein kinase C in rat hepatic stellate cells

Kobayashi, Yoshimasa, Bridle, Kim R., Ramm, Grant A., O'Neill, Rosemary, Britton, Robert S. and Bacon, Bruce R. (2007). Effect of phorbol ester and platelet-derived growth factor on protein kinase C in rat hepatic stellate cells. Liver International, 27 (8), 1066-1075. doi: 10.1111/j.1478-3231.2007.01573.x

Hepcidin gene expression is further suppressed in HFE-/-mice following chronic ethanol consumption

Fletcher, LM, Heritage, ML, Bridle, KR, Murphy, TL, Anderson, GJ and Crawford, DH (2007). Hepcidin gene expression is further suppressed in HFE-/-mice following chronic ethanol consumption. American Journal of Hematology, 82 (6), 528-529.

Coordinate activation of intracellular signaling pathways by insulin-like growth factor-1 and platelet-derived growth factor in rat hepatic stellate cells

Bridle, K. R., Li, L., O'Neill, R., Britton, R. S. and Bacon, B. R. (2006). Coordinate activation of intracellular signaling pathways by insulin-like growth factor-1 and platelet-derived growth factor in rat hepatic stellate cells. The Journal of Laboratory and Clinical Medicine, 147 (5), 234-241. doi: 10.1016/j.lab.2005.12.009

Hepcidin is down-regulated in alcoholic liver injury: Implications for the pathogenesis of alcoholic liver disease

Bridle, Kim R., Cheung, Ting-Kin, Murphy, Therese L., Walters, Margaret M., Anderson, Gregory J., Crawford, Darrell H. G. and Fletcher, Linda M. (2006). Hepcidin is down-regulated in alcoholic liver injury: Implications for the pathogenesis of alcoholic liver disease. Alcoholism-clinical And Experimental Research, 30 (1), 106-112. doi: 10.1111/j.1530-0277.2006.00002.x

Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver

Chang, P., Hung, D. Y., Siebert, G. A., Bridle, K. and Roberts, M. S. (2005). Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. Digestive Diseases And Sciences, 50 (4), 745-752. doi: 10.1007/s10620-005-2567-z

Reply

Anderson, Gregory J., Frazer, David M., Bridle, Kim R., Crawford, Darell H. G., Subramaniam, V. Nathan, Powell, Lawrie W. and Ramm, Grant A. (2004). Reply. Gastroenterology, 126 (2), 616-616. doi: 10.1053/j.gastro.2003.12.054

Identification and characterization of the hepatic stellate cell transferrin receptor

Bridle, Kim R., Crawford, Darrell H. G. and Ramm, Grant A. (2003). Identification and characterization of the hepatic stellate cell transferrin receptor. American Journal of Pathology, 162 (5), 1661-1667. doi: 10.1016/S0002-9440(10)64300-3

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis

Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Purdie, D. M., Crawford, D. H. G., Subramaniam, V. N, Powell, L. W., Anderson, G. J. and Ramm, G. A. (2003). Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet, 361 (9358), 669-673. doi: 10.1016/S0140-6736(03)12602-5

Effect of alcohol on iron storage diseases of the liver

Fletcher, LM, Bridle, KR and Crawford, DHG (2003). Effect of alcohol on iron storage diseases of the liver. Best Practice & Research In Clinical Gastroenterology, 17 (4), 663-677. doi: 10.1053/ybega.2003.378

Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis

Bridle, K. R., Crawford, D. H. G., Fletcher, L. M., Smith, J. L., Powell, L. W. and Ramm, G. A. (2003). Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis. Journal of Hepatology, 38 (4), 426-433. doi: 10.1016/S0168-8278(02)00444-0

The role of hepatic stellate cells and transforming growth factor-beta(1) in cystic fibrosis liver disease

Lewindon, PJ, Pereira, TN, Hoskins, AC, Bridle, KR, Williamson, RM and Ramm, GA (2002). The role of hepatic stellate cells and transforming growth factor-beta(1) in cystic fibrosis liver disease. American Journal of Pathology, 160 (5), 1705-1715. doi: 10.1016/S0002-9440(10)61117-0

Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis

Bridle, Kim R., Crawford, Darrell H. G., Powell, Lawrie W. and Ramm, Grant A. (2001). Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis. Liver, 21 (2), 96-104. doi: 10.1034/j.1600-0676.2001.021002096.x

Erratum: Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominantly in acinar zone 3. (Journal of Gastroenterology and Hepatology (2001) 16 (599-606))

Macdonald, G. A., Bridle, K. R. and Ward, P. J. (2001). Erratum: Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominantly in acinar zone 3. (Journal of Gastroenterology and Hepatology (2001) 16 (599-606)). Journal of Gastroenterology and Hepatology (Australia), 16 (8), 953-953. doi: 10.1046/j.1440-1746.2001.01681.x

Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3

Macdonald, G., Bridle, K. R., Ward, P. J., Walker, N. I., Houglum, K., George, D. K., Smith, J. L., Powell, L. W., Crawford, D. and Ramm, G. A. (2001). Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3. Journal of Gastroenterology and Hepatology, 16 (6), 599-606. doi: 10.1046/j.1440-1746.2001.02445.x

Morphology of liver repair following cholestatic liver injury: Resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts

Ramm, G. A., Carr, S. C., Bridle, K. R., Li, L., Britton, R. S., Crawford, D. H. G., Vogler, C. A., Bacon, B. R. and Tracy, T. F. (2000). Morphology of liver repair following cholestatic liver injury: Resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts. Liver, 20 (5), 387-396. doi: 10.1034/j.1600-0676.2000.020005387.x

Repetitive acute pancreatic injury in the mouse induces procollagen alpha(1)(I) expression colocalized to pancreatic stellate cells

Neuschwander-Tetri, BA, Bridle, KR, Wells, LD, Marcu, M and Ramm, GA (2000). Repetitive acute pancreatic injury in the mouse induces procollagen alpha(1)(I) expression colocalized to pancreatic stellate cells. Laboratory Investigation, 80 (2), 143-150. doi: 10.1038/labinvest.3780018

Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia

Ramm, G. A., Nair, V. G., Bridle, K. R., Shepherd, R. W. and Crawford, D. H. G. (1998). Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia. American Journal of Pathology, 153 (2), 527-535. doi: 10.1016/S0002-9440(10)65595-2

Hepatic iron stores and steatosis are associated with lipid peroxidation and fibrosis

Macdonald, GA, Bridle, KR, Ward, PJ, Walker, NI, Houglum, K, Powell, LW, Crawford, DHG and Ramm, GA (1998). Hepatic iron stores and steatosis are associated with lipid peroxidation and fibrosis. Hepatology, 28 (4, Part 2 Suppl.), 639A-639A.

Evidence that 'myofibroblast-like' cells are the cellular source of capsular collagen in hepatocellular carcinoma

Ooi, L. P. J., Crawford, D. H. G., Gotley, D. C., Clouston, A. D., Strong, R. W., Gobe, G. C., Halliday, J. W., Bridle, K. R. and Ramm, G. A. (1997). Evidence that 'myofibroblast-like' cells are the cellular source of capsular collagen in hepatocellular carcinoma. Journal of Hepatology, 26 (4), 798-807. doi: 10.1016/S0168-8278(97)80245-0

Effect of Extracellular-Matrix Proteins On Vascular Smooth-Muscle Cell Phenotype

Hayward, I.P., Bridle, K.R., Campbell, G.R., Underwood, P.A. and Campbell, J.H. (1995). Effect of Extracellular-Matrix Proteins On Vascular Smooth-Muscle Cell Phenotype. Cell Biology International, 19 (10), 839-846. doi: 10.1006/cbir.1995.1019

Effect of Extracellular-Matrix Proteins On Vascular Smooth-Muscle Cell Phenotype

Hayward, I.P., Bridle, K.R., Campbell, G.R., Underwood, P.A. and Campbell, J.H. (1995). Effect of Extracellular-Matrix Proteins On Vascular Smooth-Muscle Cell Phenotype. Cell Biology International, 19 (9), 727-734. doi: 10.1006/cbir.1995.1123

Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury

Baidya, R., Jaskowski, L., Gautheron, J., Jayachandran, A., Wang, H., Thevenot, P., Cohen, A., Crawford, D. and Bridle, K. (2019). Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14798

Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells

Cao, L., Shrestha, R., Bridle, K., Crawford, D. and Jayachandran, A. (2019). Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14797

Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma

Shrestha, R., Bridle, K., Cao, L., Crawford, D. and Jayachandran, A. (2019). Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Richmond, VIC, Australia: Wiley-Blackwell.

Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death

Reiling, Janske, Hohenhaus, Daniel M., Sweet, Matt J., Raj, Ashok S., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2018). Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death. 14th World Congress of the International-Pancreas-and-Islet-Transplant-Association (IPITA), Monterey Ca, 24-27 September 2013. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000543959.06247.92

Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron

Jaskowski, Lesley, Bridle, Kim, Britton, Laurence J., Jayachandran, Apama, Ramm, Grant A. and Crawford, Darrell H. G. (2018). Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA, United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury

Baidya, Raji, Jaskowski, Lesley, Jayachandran, Aparna, Thevenot, Paul, Cohen, Ari J., Crawford, Darrell H.G. and Bridle, Kim (2018). Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, California, 9-13 November 2018 . Hoboken, NJ, United States: John Wiley & Sons.

Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

Shrestha, Ritu, Prithiviraj, Prashanth, Bridle, Kim, Anake, Matthew, Crawford, Darrell H. G. and Jayachandran, Aparna (2018). Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, CA United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?

Reiling, J., Bridle, K. B., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Damink, S. W. M. Olde, Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?. HOBOKEN: WILEY.

Iron blocks the secretion of apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, K., Jaskowski, L. A., He, J., Ng, C., Ruelcke, J. E., Reiling, J., Santrampurwala, N., Hill, M. M., Whitehead, J. P., Subramaniam, V. N. and Crawford, D. H. G. (2017). Iron blocks the secretion of apolipoprotein E in cultured human adipocytes. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology , Gold Coast, QLD, Australia, 20–22 August 2017. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Liver disease in Vietnam veterans: a comparison of veterans with and without PTSD

Hlaing, P. M., Bridle, K. R., Jaskowski, L. A., Harvey, W. M. and Crawford, D. H. G. (2016). Liver disease in Vietnam veterans: a comparison of veterans with and without PTSD. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

The application of normothermic machine perfusion to bench-test human donor livers

Reiling, J., Simpson, A., Bridle, K. R., Lockwood, D., Santrampurwala, N., Britton, L., Dejong, C. H. C., Crawford, D. H. G. and Fawcett, J. (2016). The application of normothermic machine perfusion to bench-test human donor livers. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes

Santrampurwala, N., Bridle, K. R., Reiling, J., Britton, L. J., Jaskowski, L. A., Subramaniam, V. N. and Crawford, D. H. G. (2015). Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Pre-treatment with TIMP-3 prevents the development of biliary injury in an LPS enhanced ischaemia-reperfusion animal model

Reiling, J., Bridle, K., Campbell, C., Santrampurwala, N., Britton, L., Cohen, A., Crawford, D., Dejong, C. and Fawcett, J. (2015). Pre-treatment with TIMP-3 prevents the development of biliary injury in an LPS enhanced ischaemia-reperfusion animal model. World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease

Britton, L., Bridle, K., Reiling, J., Santrampurwala, N., Wockner, L., Ching, H., Subramaniam, V., Crawford, D. and Adams, L. (2015). Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model

Reiling, J., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12736_8

Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers

Reiling, J., Lockwood, D. S. R., Simpson, A. H., Campbell, C. M., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, United States, 7 - 11 November 2014. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

Wilkinson, Ashley S., Bridle, Kim, Britton, Laurence, Jaskowski, Lesley, Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2013). Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington, DC, United States, 1 - 5 November 2013. Hoboken, NJ, United States: John Wiley & Sons.

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

Wilkinson, A. S., Bridle, K. R., Britton, L. J., Jaskowski, L. A., Fletcher, L. M., Subramaniam, V. N. and Crawford, D. H. G. (2013). An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

Britton, Laurence, Jaskowski, Lesley, Wilkinson, Ashley, Bridle, Kim, Subramaniam, Nathan and Crawford, Darrell (2013). Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

Britton, L., Jaskowski, L., Wilkinson, A., Bridle, K., Subramaniam, N. and Crawford, D. (2013). Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

Santrampurwala, N., Bridle, K. R., Heritage, M. L., Jaskowski, L. A., Wilkinson, A. S., Subramaniam, V. N. and Crawford, D. H. G. (2013). Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

Sobbe, A. L., Frazer, D. M., Bridle, K. R., Jaskowski, L. A., Anderson, G. J., Subramaniam, V. N. and Crawford, D. H. (2013). Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

Sobbe, Amy, Frazer, David, Bridle, Kim, Jaskowski, Lesley, Ostini, Lesa, de Guzman, Erika, Santrampurwala, Nishreen, Anderson, Gregory, Subramaniam, V. Nathan and Crawford, Darrell (2013). Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD

Wilkinson, Ashley S., Heritage, Mandy L., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Clouston, Andrew, Bridle, Kim, Macdonald, Graeme A., Anderson, Gregory, Fletcher, Linda M., Subramaniam, Nathan and Crawford, Darrell H. (2012). Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice

Sobbe, Amy, Bridle, Kim, de Guzman, Cloe Erika, Santrampurwala, Nishreen, Subramaniam, Nathan and Crawford, Darrell H. (2012). Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, 9-13 November 2012. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/hep.26040

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy L., Wilkinson, Ashley S., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Bridle, Kim, Clouston, Andrew, Anderson, Gregory, Fletcher, Linda M., Macdonald, Graeme A., Subramaniam, Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. Abstracts of the Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators

Marbach, J., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis

Hsu, L., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism

Sobbe, A. L., Bridle, K. R., Jaskowski, L. A., Ostini, L., De Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis

Sobbe, A., Bridle, K., Jaskowski, L., Ostini, L., de Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis

Bridle, K. R., Sobbe, A., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Fletcher, L. and Crawford, D. H. (2011). Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis

Heritage, M., Stuart, K. A., Bridle, K., Murphy, T. L., Sobbe, A., Jaskowski, L., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis

Heritage, M. L., Stuart, K. A., Bridle, K. R., Murphy, T. L., Sobbe, A. L., Jaskowski, L. A., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. G. (2011). The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Altered expression of iron-regualtory genes in an animal model of cholestasis

Sobbe, A. L., Bridle, K.R., Fletcher, L. and Crawford, D, H. G. (2010). Altered expression of iron-regualtory genes in an animal model of cholestasis. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2010.06450.x

Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis C

Sobbe, A.L., Bridle, K.R., Morgan, M.L., Lipka, G., Fletcher, L. and Crawford, D.H.G. (2009). Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis C. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney Convention & Exhibition Centre, Sydney, NSW, Australia, 21-24 October 2009. Carlton South, Vic.: Blackwell Publishing Asia.

The antifibrotic effect of low dose rapamycin is diminished in Mdr2-/- when administered to animals with advanced hepatic fibrosis

Sobbe, AL, Bridle, KR and Crawford, DHG (2009). The antifibrotic effect of low dose rapamycin is diminished in Mdr2-/- when administered to animals with advanced hepatic fibrosis. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney, Australia, 21-24 October 2009. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

Hepcidin regulation in response to alcohol consumption: evidence for an alcohol-induced hypoxic response

Heritage, M. L., Jaskowski, L. A., Bridle, K. R., Murphy, T. L., Anderson, G. J., Crawford, D. H. and Fletcher, L. M. (2008). Hepcidin regulation in response to alcohol consumption: evidence for an alcohol-induced hypoxic response. Australian Gastroenterology Week, Brisbane, Qld, Australia, 22-25 October, 2008. Carlton South, Vic, Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2008.05613.x

Hepcidin regulation in wild-type and HFE-/mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Bridle, K. R., Anderson, G. J. and Crawford, D. H. (2008). Hepcidin regulation in wild-type and HFE-/mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. 43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy, 23-27 April, 2008. Copenhagen, Denmark: Elsevier. doi: 10.1016/S0168-8278(08)60888-0

Hepcidin regulation in wild-type and Hfe(-/-) mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

FletcherLM, Heritage, ML, MurphyTL, BridleKR, AndersonGJ and CrawfordDH (2008). Hepcidin regulation in wild-type and Hfe(-/-) mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. 43rd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Milan ITALY, APR 23-27, 2008. doi: 10.1016/S0168-8278(08)60888-0

Multiple pathways to hepatic fibrosis are inhibited by rapamycin

Bridle, K. R., Sobbe, A. L., Fletcher, L. M., Clouston, A. D. and Crawford, D. H. G. (2008). Multiple pathways to hepatic fibrosis are inhibited by rapamycin. Australian Gastroenterology Week 2008, Brisbane, Qld, Australia, 22-25 October 2008. Carlton South, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2008.05613.x

Rapamycin as an inhibitor of hepatic fibrosis: relevance to whole blood levels

Popa, C., Bridle, K. R., Morgan, M. L., Clouston, A. D., Fletcher, L. M. and Crawford, D. H. G. (2008). Rapamycin as an inhibitor of hepatic fibrosis: relevance to whole blood levels. 43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy, 23-27 April, 2008. Ireland: Elsevier. doi: 10.1016/S0168-8278(08)60467-5

Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis

Heritage, M. L., Murphy, T. L., Popa, C., Bridle, K. R., Anderson, G. J., Crawford, D. H. G. and Fletcher, L. M. (2007). Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis. Australian Gastroenterology Week 2007, Perth, Australia, 24–27 October 2007. Melbourne, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2007.05161.x

Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Popa, C., Bridle, K. R., Anderson, G. J. and Crawford, D. H. (2007). Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis. 58th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, U.S.A., 1-6 November 2007. U.S.A.: Wiley InterScience. doi: 10.1002/hep.22022

Hepciden gene expression is further suppressed in Hfe-/- mice following chronic ethanol consumption

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Bridle, K. R., Anderson, G. J. and Crawford, D. H. G. (2007). Hepciden gene expression is further suppressed in Hfe-/- mice following chronic ethanol consumption. 2007 International BioIron Society Meeting, Kyoto, Japan, 1-6 April, 2007. New York: Wiley-LISS. doi: 10.1002/ajh.20964

Rapamycin as an anti-fibrotic agent

Popa, C., Bridle, K. R., Morgan, M. L., Robinson, M. W., Fletcher, L. M. and Crawford, D. H. (2007). Rapamycin as an anti-fibrotic agent. Australian Gastroenterology Week, Perth, Australia, 24-27 October 2007. Australia. doi: 10.1111/j.1440-1746.2007.05161.x

Post liver transplantation disease recurrence: influence of matrix degradation proteins

Bridle, K. R., Murphy, T. L., Fletcher, L. M. and Crawford, D. H. G. (2006). Post liver transplantation disease recurrence: influence of matrix degradation proteins. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Serum adiponectin is increased in HFE-/- mice fed alcohol

Bridle, K. R., Murphy, T. L., Anderson, G. J., Macdonald, G. A., Crawford, D. H. G. and Fletcher, L. M. (2006). Serum adiponectin is increased in HFE-/- mice fed alcohol. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Very low dose rapamycin : In vitro evidence for its use as an antifibrotic agent

Morgan, M. L., Bridle, K. R., Fletcher, L. M. and Crawford, D. H. G. (2006). Very low dose rapamycin : In vitro evidence for its use as an antifibrotic agent. Australian Gastroenterology Week, Adelaide, SA, Australia, 11-14 October 2006. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Very low dose rapamycin: in vitro evidence for its use as an antifibrotic agent

Morgan, M. L., Bridle, K. R., Fletcher, L. M. and Crawford, D. H. G. (2006). Very low dose rapamycin: in vitro evidence for its use as an antifibrotic agent. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis

Bridle, K. R., Patella, S., Tchongue, J., Fletcher, L. M., Sievert, W. and Crawford, D. H. G. (2006). Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis. Australian Gastroenterology Week, Adelaide, Australia, 11–14 October 2006. Oxford United Kingdom: Wiley.

Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis

Bridle, K. R., Patella, S., Tchongue, J., Fletcher, L. M., Sievert, W. and Crawford, D. H. G. (2006). Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Expression of the iron regulatory peptide hepcidin is reduced in patients with chronic liver disease

Anderson, Greg, Frazer, David M., Bridle, Kim R., Macdonald, Graeme A., Smith, Jeffrey L., Turlin, Bruno, Subramaniam, Nathan, Crawford, Darrell H., Powell, Lawrie W. and Ramm, Grant A. (2005). Expression of the iron regulatory peptide hepcidin is reduced in patients with chronic liver disease. 47th Annual Meeting of the American Society of Hematology, Atlanta, Georgia, USA, 10-13 December, 2005. Washington, D.C., USA: American Society of Hematology.

Optimising conditions for assessing glucose output from isolated rat hepatocytes in response to insulin

Stephenson, M. D., Bridle, K. R., Whitehead, J. P. and Macdonald, G. A. (2005). Optimising conditions for assessing glucose output from isolated rat hepatocytes in response to insulin. Australian Gastroenterology Week 2005, Brisbane, Qld, Australia, 19-22 October, 2005. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2005.04091_4.x

Rapamycin, but not cyclosporine A or tacrolimus, reduces hepatic stellate cell activation: implications for post-transplant fibrogenesis

Bridle, K. R., Robinson, M. W., Fletcher, L. M. and Crawford, D. H. (2005). Rapamycin, but not cyclosporine A or tacrolimus, reduces hepatic stellate cell activation: implications for post-transplant fibrogenesis. Australian Gastroenterology Week 2005, Brisbane, Qld, Australia, 19-22 October, 2005. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2005.04091_4.x

Alcohol-induced down-regulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, K. R., Murphy, T., Walters, M., Crawford, D. H. G. and Fletcher, L. M. (2004). Alcohol-induced down-regulation of hepcidin mRNA expression is mediated by oxidative stress. Australian Gastroenterology Week 2004, Brisbane Convention Centre, Brisbane Qld, Australia, 4-8 October, 2004. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2004.3615_3..x

Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, K., Murphy, T., Walters, M., Crawford, D. and Fletcher, L. (2004). Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress. 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston MA, United States, Oct 29 - Nov 02 2004. Hoboken, NJ United States: John Wiley & Sons.

Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, Kim, Crawford, Darrell, Fletcher, Linda, Murphy, Therese and Walters, Margaret (2004). Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress. The Liver Meeting 2004: 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, U.S.A., 29 October-2 November 2004. Hoboken, NJ, U.S.A: John Wiley & Sons. doi: 10.1002/hep.1840400508

Factors affecting the gene expression of hepcidin in chronic viral hepatitis C

Bridle, K. R., Fletcher, L. M., Jonsson, J. R., Richardson, M. M., Clouston, A. D., Powell, E. E. and Crawford, D. H. G. (2004). Factors affecting the gene expression of hepcidin in chronic viral hepatitis C. Australian Gastroenterology Week 2004, Brisbane Convention Centre, Brisbane, Qld Australia, 4-8 October, 2004. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2004.3615_3..x

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia

Bridle, K. R., Fletcher, L. M., Murphy, T., Walters, M., Hung, D., Chang, P., Siebert, G., Roberts, M. and Crawford, D. H. G. (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24-28 October 2003. Carlton South, Vic.: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia

Fletcher,Linda, Bridle, Kim, Murphy, Therese, Walters, Margaret, Hung, Daniel, Chang, Ping, Siebert, Gerhard, Roberts, Michael and Crawford, Darrell (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24 - 28 October, 2003. Hoboken, NJ, U.S.A: Wiley Interscience. doi: 10.1002/hep.1840380508

Failure of hepcidin upregulation in HFE-associated haemochromatosis implicates the liver in the regulation of body iron homeostasis

Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Millard, K. N., Crawford, D. H. G., Subramaniam, V. N., Powell, L. W., Anderson, G. J. and Ramm , G. A. (2003). Failure of hepcidin upregulation in HFE-associated haemochromatosis implicates the liver in the regulation of body iron homeostasis. Australian Gastroenterology Week, Cairns, Australia, 7-10 October 2003. Carlton South, Vic., Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis

Cheung, T. K., Fletcher, L., Bridle, K., Murphy, T. and Crawford, D. (2003). Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis. 54th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, Boston MA, United States, Oct 24-28, 2003. Hoboken, NJ United States: John Wiley & Sons.

Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis.

Bridle, Kim, Cheung, Ting Kin, Crawford, Darrell, Fletcher, Linda and Murphy, Therese (2003). Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis.. The Liver Meeting 2003: 54th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, U.S.A., 25-28 October 2003. 0270-9139 (print); 1527-3350 (electronic): John Wiley & Sons. doi: 10.1002/hep.1840380508

Reduced hepcidin expression in alcohol-fed rats may be a contributing factor in alcoholic hepatic siderosis

Cheung, T. K., Fletcher, L. M., Bridle, K. R., Murphy, T. L. and Crawford, D. H. G. (2003). Reduced hepcidin expression in alcohol-fed rats may be a contributing factor in alcoholic hepatic siderosis. Australian Gastroenterology Week 2003, Cairns, QLD, Australia, 7-10 Ocrober, 2003. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

Hepatic fibrogenesis in cystic fibrosis liver disease

Blanch, N. L., Bridle, K., Greco, S., Lewindon, P., Murphy, T. M., Pereira, T., Ramm, G. A., Shepherd, R. W., Smith, J. L. and Walker, N. I. (1999). Hepatic fibrogenesis in cystic fibrosis liver disease. 50th Annual Meeting and Postgraduate Conference, Dallas, Texas, Nov 1999. USA: Harcourt and Brace (WD Saunders).

Identification and characterisation of a receptor for transferrin on hepatic stellate cells: role in the transformation to myofibroblasts

Bridle, K., Blanch, N. L., Crawford, D. H. and Ramm, G. A. (1999). Identification and characterisation of a receptor for transferrin on hepatic stellate cells: role in the transformation to myofibroblasts. Australian Gastroenterology Week 1999, Brisbane, 4 - 8 Oct, 1999. Carlton, Vic: Blackwell Science Asia.

Identification and characterisation of the hepatic stellate cell transferrin receptor and influence of transferrin on hepatic stellate cell activation

Bridle, K., Stewart, N. L., Crawford, D. H., Anderson, G. and Ramm, G. A. (1999). Identification and characterisation of the hepatic stellate cell transferrin receptor and influence of transferrin on hepatic stellate cell activation. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, 23 - 28 May 1999. Italy: SGC.

The contribution of inflammatory cells to iron-induced hepatic fibrogenesis in hemochromatosis

Bridle, K. R., Crawford, D. H. G., Smith, J. L., Fletcher, L. M., Walker, N. I. and Ramm, G. A. (1998). The contribution of inflammatory cells to iron-induced hepatic fibrogenesis in hemochromatosis. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

In vivo hepatic activities of matrix metalloproteinases-2, 3 and 9 are increased in prefibrotic animal and human iron overload

George, D.K., Ramm, G.A., Bridle, K.R., Fletcher, L.M. and Crawford, D.H.G. (1997). In vivo hepatic activities of matrix metalloproteinases-2, 3 and 9 are increased in prefibrotic animal and human iron overload. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

Interferon-gamma but not transforming growth factor-beta gene expression is upregulated in liver tissue of patients with genetic hemochromatosis

Bridle, K.R., Crawford, D.H.G., Fletcher, L.M. and Ramm, G.A. (1997). Interferon-gamma but not transforming growth factor-beta gene expression is upregulated in liver tissue of patients with genetic hemochromatosis. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

The role of activated hepatic stellate cells in capsule formation in hepatocellular carcinoma and colorectal metastases to the liver

Ramm, G.A., Ooi, L. L. P. J., Gotley, D. C., Clouston, A. D., Bridle, K. R. and Crawford, D. H. G. (1997). The role of activated hepatic stellate cells in capsule formation in hepatocellular carcinoma and colorectal metastases to the liver. 8th International Symposium on the Cells of the Hepatic Sinusoid, Bordeaux, France, 1-5 September 1996. Leiden, Netherlands: Kupffer Cell Foundation.

Biliary decompression results in rapid reversal of procollagen alpha(1)(I) gene expression in experimental biliary fibrosis

Ramm, G.A., Crawford, D.H.G., Bridle, K.R., Britton, R.S. and Bacon, B.R. (1996). Biliary decompression results in rapid reversal of procollagen alpha(1)(I) gene expression in experimental biliary fibrosis. 47th Annual Meeting of the American Association for the Study of Liver Disease, Chicag, Il, United States, 8-12 November 1996. Hoboken, NJ, United States: John Wiley & Sons.