Dr Jasim Uddin

Adjunct Senior Lecturer

School of Veterinary Science
Faculty of Science

Overview

I am passionate about the teaching and research on infectious diseases, and production of livestock to enhance animal (and human) health and welfare, and food security. My specific focus is to unravel the host-pathogen interactions using molecular and genomic techniques to improve disease resistance and benefit livestock industries. I also focus on meat quality and production traits of food animals to enhance the sustainability and quality of future food sources. My goal is to be recognized as a leading expert in these areas within both scientific circles and the livestock industry, and, to lead and train others in this work.

I am qualified and experienced academic and researcher who has held positions across universities and laboratories in Australia, Germany, and Bangladesh. I awarded DVM (Doctor of Veterinary Medicine) and MS from Bangladesh Agricultural University, and PhD from University of Bonn. Prior to joining in Murdoch University, I worked as an Associate Professor in Bangladesh Agricultural University, and as a Research Fellow in University of Bonn, and University of Queensland. I also worked as a Scientist (Virology) in the State (Queensland) Veterinary Research and Diagnostic Laboratory.

My research attracts both public and industry grants and establishes excellent collaborations with universities and industries nationally and internationally. My high-quality research publications, notably journal papers and industry reports, have also covered the animal health, welfare, and productions. I have received several awards including Best publication award and travels grants. I aim to continue to contribute to science and to produce such research outputs with collaboration networks. I aim to lead an applied research team with both scientific research and industry collaboration funding. I am actively looking for potential HDR students and research collaborations. Murdoch University offers scholarships for both domestic and international students. As infectious diseases and future food security become more topical, I anticipate that there will be increasing opportunity for research and collaborations to the broader community.

Research Interests

  • Genetics and genomics behind the production traits of livestock for sustainable animal productions
  • Identification of candidate genes and genetic markers controlling the immune competence and production traits in livestock.
  • Epigenetics of immune response and muscle growth in porcine model.
  • Host-pathogen interactions using next generation genomics and epigenetics tools.

Research Impacts

My present research School of Veterinary Science, UQ is to investigate the pathogenomics features of West Nile virus (WNV) in horses and model animal rabbits. We have established a new model for non-lethal WNV study model, the New Zealand White rabbit. I have eludicated the transcriptome response of equine and rabbit blood mononulcear cells induced by WNV. I have studied various aspects of animal genetics, genomics, and immunology, and virology during my PhD and subsequently workings as Research Associte in the Institute of Animal Science, University of Bonn. I have scanned the porcine genome to identify quantitative trait loci (QTL) affecting the antibody production against infectious disease and the QTL affecting the levels of innate immune components so that candidate genes and genetic markers could be identified with an aim to use in selective breeding to develop disease resistant lines. The transcriptomic expression variation with ages has been demonstrated to elucidate the host immune response variation with age. I have extended my work to identify QTL, candidate genes, markers, and epigenetics that are involved in porcine leg weakness and in the process of osteochondrosis development. My work has shed light on the patterns of immunological responses of porcine peripheral blood lymphocytes, alveolar macrophages and dendritic cells to bacterial products. I have contributed to transcriptome quantitation and association studies of genes and markers pivotal for boar fertility and meat quality traits. I have identified QTL that affect cholesterol, HDL, LDL and triglyceride levels in porcine, which is the most approximate model to human. Subsequently, I worked as a Research Associate (full-time) with special duty as “Group Leader for the Molecular Genetics of Pig group” in the IAS, UB in the host lab of Prof. Karl Schellander. I have worked in four different projects related to i) Meat Quality Trait-Drip loss: global transcriptome profiling, eQTL and genome wide association study for meat quality trait Drip loss, ii) Meat Quality Trait- Boar Taint: deciphering genomics of boar taint using next generation sequencing (NGS), iii) Immuno-genomics: cross-talk between porcine cells and PRRSV (porcine reproductive and respiratory syndrome virus): host pathogen interaction using NGS and microarray; innate immune responses of porcine cells induced by LPS and LTA, and iv) Epigenetics- immune response & growth: modulatory effects of HDAC inhibitor sulforaphane on the innate immune response of pigs, and epigenetics of myostatin gene and muscle development.

Qualifications

  • Doctor of Agricultural Sciences, University of Bonn
  • Master of Science, B'desh.Ag.
  • Doctor of Veterinary Medicine, B'desh.Ag.

Publications

View all Publications

Publications

Journal Article

Conference Publication

  • Listyarini, K., Sumantri, C., Rahayu, S., Uddin, M. J. and Gunawan, A. (2021). Identification and association of polymorphism in THOC5 gene with fatty acid composition in Indonesian sheep. 3rd International Conference of Animal Science and Technology, ICAST 2020, Makassar, Indonesia, 3 - 4 November 2020. Bristol, United Kingdom: IOP Publishing. doi: 10.1088/1755-1315/788/1/012020

  • Listyarini, K., Jakaria,, Furqon, A., Sumantri, C., Uddin, M. J. and Gunawan, A. (2018). Expression of CYP2A6, KIF12, and SULT1C1 in liver of sheep with divergent sheepmeat flavour and odour. 1st International Conference on Food Security and Sustainable Agriculture in The Tropics, IC-FSSAT 2017, Sulawesi Selatan, Indonesia, 24–25 October 2017. Bristol, United Kingdom: Institute of Physics Publishing. doi: 10.1088/1755-1315/157/1/012029

  • Abuzahra, M. A.M., Jakaria,, Listyarini, K., Furqon, A., Sumantri, C., Uddin, M. J. and Gunawan, A. (2018). Variant discovery in the sheepmeat odour and flavour in Javanese fat tailed sheep using RNA sequencing. 1st International Conference on Food Security and Sustainable Agriculture in The Tropics, IC-FSSAT 2017, Sulawesi Selatan, Indonesia, 24–25 October 2017. Bristol, United Kingdom: Institute of Physics Publishing. doi: 10.1088/1755-1315/157/1/012030

  • Uddin, Jasim M., Suen, Willy, Prow, Natalie A, Hall, Roy A. and Bielefeldt-Ohmann, Helle (2014). West Nile virus (WNV) infection alters the cytokines and TLRs transcriptome profiles in rabbit PBL. 2nd Annual Meeting of the International Cytokine and Interferon Society (ICIS), Melbourne, VIC Australia, 26 - 29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.194

  • Gunawan, A., Kaewmala, K., Uddin, M. J., Cinar, M. U., Tesfaye, D., Tholen, E., Looft, C. and Schellander, K. (2011). Expression analysis of porcine aromatase (CYP19) as a specific target gene in testis. 7th International Conference on Boar Semen Preservation, Bonn, Germany, 14-17 August 2011. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/j.1439-0531.2011.01854.x