The University of Queensland

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

Millard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058

Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Wu, Andy C., Kaur, Simranpreet, Sun, Lucas W.H., Williams, Kyle, Sandrock, Cheyenne, Ng, Pei Ying, Irvine, Katharine M., Bartnikowski, Michal, Glatt, Vaida, Pavlos, Nathan J. and Pettit, Allison R. (2021). Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. Journal of Bone and Mineral Research, 36 (11), 2214-2228. doi: 10.1002/jbmr.4413

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936. doi: 10.1016/j.biomaterials.2021.120936

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033

Osteomacs and bone regeneration

Batoon, Lena, Millard, Susan Marie, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). Osteomacs and bone regeneration. Current Osteoporosis Reports, 15 (4), 385-395. doi: 10.1007/s11914-017-0384-x

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

Alexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

Kaur, Simranpreet, Raggatt, Liza Jane, Batoon, Lena, Hume, David Arthur, Levesque, Jean-Pierre and Pettit, Allison Robyn (2016). Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches. Seminars in Cell and Developmental Biology, 61, 12-21. doi: 10.1016/j.semcdb.2016.08.009

Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts

Millard, Susan M., Pettit, Allison R., Ellis, Rebecca, Chan, Jerry K. Y., Raggatt, Liza J., Khosrotehrani, Kiarash and Fisk, Nicholas M. (2015). Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts. Stem Cell Reports, 5 (5), 682-689. doi: 10.1016/j.stemcr.2015.09.017

Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification

Raggatt, Liza J., Wullschleger, Martin E., Alexander, Kylie A., Wu, Andy C. K., Millard, Susan M., Kaur, Simranpreet, Maugham, Michelle L., Gregory, Laura S., Steck, Roland and Pettit, Allison R. (2014). Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification. American Journal of Pathology, 184 (12), 3192-3204. doi: 10.1016/j.ajpath.2014.08.017

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse

Jacobsen, Rebecca N., Forristal, Catherine E., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Kaur, Simranpreet, van Rooijen, Nico, Winkler, Ingrid G., Pettit, Allison R. and Levesque, Jean-Pierre (2014). Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse. Experimental Hematology, 42 (7), 547-561. doi: 10.1016/j.exphem.2014.03.009

Unraveling macrophage contributions to bone repair

Wu, Andy C., Raggatt, Liza J., Alexander, Kylie A. and Pettit, Allison R. (2013). Unraveling macrophage contributions to bone repair. BoneKEy Reports, 2 (373), 1-1. doi: 10.1038/bonekey.2013.107

Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury model

Raggatt, Liza J., Alexander, Kylie A., Kaur, Simranpreet, Wu, Andy C., MacDonald, Kelli P. A. and Pettit, Allison R. (2013). Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury model. American Journal of Pathology, 182 (5), 1501-1508. doi: 10.1016/j.ajpath.2013.01.046

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

Roberts, Tara L., Ho, Uda, Luff, John, Lee, C. Soon, Apte, Simon H., MacDonald, Kelli P. A., Raggatt, Liza-Jane, Pettit, Allison R., Morrow, Carl A., Waters, Michael J., Chen, Phil, Woods, Rick G., Thomas, Gethin P., St. Pierre, Liam, Farah, Camile S., Clarke, Raymond A., Brown, James A. L. and Lavin, Martin F. (2013). Smg1 haploinsufficiency predisposes to tumor formation and inflammation. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 110 (4), E285-E294. doi: 10.1073/pnas.1215696110

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation

Winkler, I. G., Pettit, A. R., Raggatt, L. J., Jacobsen, R. N., Forristal, C. E., Barbier, V., Nowlan, B., Cisterne, A., Bendall, L. J., Sims, N. A. and Levesque, J-P. (2012). Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia, 26 (7), 1594-1601. doi: 10.1038/leu.2012.17

Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

Alexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Winkler, Ingrid G., Sims, Natalie A., Pettit, Allison R., Barbier, Valérie, Nowlan, Bianca, Helwani, Falak, Poulton, Ingrid J., van Rooijen, Nico van, Alexander, Kylie A., Raggatt, Liza J. and Levesque, Jean-Pierre (2010). Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood, 116 (23), 4815-4828. doi: 10.1182/blood-2009-11-253534

Cellular and molecular mechanisms of bone remodeling

Raggatt, Liza J. and Partridge, Nicola C. (2010). Cellular and molecular mechanisms of bone remodeling. Journal of Biological Chemistry, 285 (33), 25103-25108. doi: 10.1074/jbc.R109.041087

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1

Summers, Kim M., Bokil, Nilesh J., Baisden, John M., West, Malcolm J., Sweet, Matthew J., Raggatt, Liza J. and Hume, David A. (2009). Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1. Genomics, 94 (4), 233-240. doi: 10.1016/j.ygeno.2009.06.005

Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation

Markey, KA, Banovic, T, Kuns, RD, Olver, SD, Don, ALJ, Raffelt, NC, Wilson, YA, Raggatt, LJ, Pettit, AR, Bromberg, JS, Hill, GR and MacDonald, KPA (2009). Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation. BLOOD, 113 (22), 5644-5649. doi: 10.1182/blood-2008-12-191833

Osteal macrophages: A new twist on coupling during bone dynamics

Pettit, A. R., Chang, M. K., Hume, D. A. and Raggatt, L. J. (2008). Osteal macrophages: A new twist on coupling during bone dynamics. Bone, 43 (6), 976-982. doi: 10.1016/j.bone.2008.08.128

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

Chang, Ming K., Raggatt, Liza-Jane, Alexander, Kylie A., Kuliwaba, Julia S., Fazzalari, Nicola L., Schroder, Kate, Maylin, Erin R., Ripoll, Vera M, Hume, David A. and Pettit, Allison R. (2008). Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo. The Journal of Immunology, 181 (2), 1232-1244. doi: 10.4049/jimmunol.181.2.1232

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

Pettit, Allison R., Hume, David A. and Raggatt, Liza-Jane (2008). Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats. Bone, 42 (4), 825-825. doi: 10.1016/j.bone.2007.12.217

Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions

Raggatt, Liza-Jane, Qin, Ling, Tamasi, Joseph, Jefcoat, Jr., Stephen C., Shimizu, Emi, Selvamurugan, Nagarajan, Liew, Foo Y., Bevelock, Laura, Feyen, Jean H. M. and Partridge, Nicola C. (2008). Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions. The Journal of Biological Chemistry, 283 (11), 6790-6798. doi: 10.1074/jbc.M709909200

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

Ripoll, V. M, Meadows, N. A., Raggatt, L. J., Chang, M. K., Pettit, A. R., Cassady, A. I. and Hume, D. A. (2008). Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene, 413 (1-2), 32-41. doi: 10.1016/j.gene.2008.01.014

Investigations into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) surface properties causing delayed osteoblast growth

Keen, I., Raggatt, L.J., Cool, S.M., Nurcombe, V., Fredericks, P., Trau, M. and Grondahl, L. (2007). Investigations into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) surface properties causing delayed osteoblast growth. Journal of Biomaterials Science-polymer Edition, 18 (9), 1101-1123. doi: 10.1163/156856207781554046

Matrix metalloproteinase-13 influences ERK signalling in articular rabbit chondrocytes

Raggatt, L. J., Jefcoat, S. C., Choudhury, I., Williams, S., Tiku, M. and Partridge, N. C. (2006). Matrix metalloproteinase-13 influences ERK signalling in articular rabbit chondrocytes. Osteoarthritis and cartilage, 14 (7), 680-689. doi: 10.1016/j.joca.2006.01.006

Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation

Qin, Ling, Tamasi, Joseph, Raggatt, Liza, Li, Xin, Feyen, Jean H. M., DiCicco-Bloom|, Emanuel and Partridge, Nicola C. (2005). Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation. Journal of Biological Chemistry, 280 (5), 3974-3981. doi: 10.1074/jbc.M409807200

Parathyroid Hormone: a Double-Edged Sword for Bone Metabolism

Qin, Ling, Raggatt, Liza J. and Partridge, Nicola C. (2004). Parathyroid Hormone: a Double-Edged Sword for Bone Metabolism. Trends in Endocrinology & Metabolism, 15 (2), 60-65. doi: 10.1016/j.tem.2004.01.006

Impairment of the Collagenase-3 Endocytotic Receptor System in Cells from Patients with Osteoarthritis

Walling, H. W., Raggatt, L. J., Irvine, D. W., Barmina, O. Y., Toledano, J. E., Goldring, M. B., Hruska, K. A., Adkisson, H. D., Burdge, R. E., Gatt, C. J. Jr., Harwood, D. A. and Partridge, N. C. (2003). Impairment of the Collagenase-3 Endocytotic Receptor System in Cells from Patients with Osteoarthritis. Osteoarthritis and Cartilage, 11 (12), 854-863. doi: 10.1016/S1063-4584(03)00170-5

Calcitonin Decreases the Adherence and Survival of HEK-293 Cells by a Caspase-Independent Mechanism

Findlay, D. M., Raggatt, L. J., Bouralexis, S., Hay, S., Atkins, G. J. and Evdokiou, A. (2002). Calcitonin Decreases the Adherence and Survival of HEK-293 Cells by a Caspase-Independent Mechanism. Journal of Endocrinology, 175 (3), 715-725. doi: 10.1677/joe.0.1750715

HMG-CoA Reductase Inhibitors as Immunomodulators: Potential Use in Transplant Rejection

Raggatt, Liza J. and Partridge, Nicola C. (2002). HMG-CoA Reductase Inhibitors as Immunomodulators: Potential Use in Transplant Rejection. Drugs, 62 (15), 2185-2191. doi: 10.2165/00003495-200262150-00002

Expression of Alternatively-spliced MDM2 Transcripts in Giant Cell Tumours of Bone

Evdokiou, A., Atkins, G. J., Bouralexis, S., Hay, S., Raggatt, L. J, Cowled, P. A., Graves, S. E., Clayer, M. and Findlay, D. M. (2001). Expression of Alternatively-spliced MDM2 Transcripts in Giant Cell Tumours of Bone. International Journal of Oncology, 19 (3), 625-632.

Identification of a novel calcitonin receptor response element in the promoter of the human p21WAF1/CIP1 gene

Evdokiou, A., Raggatt, L. J., Sakai, T. and Findlay, M. D. (2000). Identification of a novel calcitonin receptor response element in the promoter of the human p21WAF1/CIP1 gene. Journal Of Molecular Endocrinology, 25 (2), 195-206. doi: 10.1677/jme.0.0250195

Sustained Activation of Erk1/2 MAPK and Cell Growth Suppression by the Insert-negative, but not the Insert-positive Isoform of the Human Calcitonin Receptor

Raggatt, L. J., Evdokiou, A. and Findlay, D. M. (2000). Sustained Activation of Erk1/2 MAPK and Cell Growth Suppression by the Insert-negative, but not the Insert-positive Isoform of the Human Calcitonin Receptor. Journal of Endocrinology, 167 (1), 93-105. doi: 10.1677/joe.0.1670093

Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest

Evdokiou, Andreas, Raggatt, Liza-Jane, Atkins, Gerald J. and Findlay, David M. (1999). Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest. Molecular Endocrinology, 13 (10), 1738-1750. doi: 10.1210/me.13.10.1738

Activation of the insert negative human calcitonin receptor: Phosphorylation of MAP kinase and inhibition of cellular proliferation

Raggatt, L. J., Evdokiou, A. and Findlay, D. M. (1999). Activation of the insert negative human calcitonin receptor: Phosphorylation of MAP kinase and inhibition of cellular proliferation. Journal of Bone and Mineral Research, 14 (SA042 Suppl.), x.

Differential expression of MDM2 splice variants in bone tumors

Evdokiou, A., Atkins, G. J., Bouralexis, S., Hay, S. J., Raggatt, L. J., Graves, S. E. and Findlay, D. M. (1999). Differential expression of MDM2 splice variants in bone tumors. Molecular Biology of the Cell, 10 (Suppl .), 2475.

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology

Pettit, Allison, Batoon, Lena, Millard, Susan, Wu, Andy and Raggatt, Liza (2019). Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology. Annual Meeting of the American Society for Bone and Mineral Research, Orlando, FL, United States, 20-23 September, 2019. Hoboken, NJ, United States: Wiley-Blackwell Publishing Asia.

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

Levesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Kaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral Ossification

Pettit, A., Raggatt, L., Wullschleger, M., Alexander, K., Steck, R., Kaur, S. and Wu, A. (2013). Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral Ossification. Annual Meeting of the American Society for Bone and Mineral Research, Baltimore MD United States, 4-7 October 2013. Hoboken, NJ United States: Wiley-Blackwell.

Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages

Jacobsen, Rebecca, Pettit, Allison, Barbier, Valerie, Nowlan, Bianca, Raggatt, Liza, Winkler, Ingrid and Levesque, Jean-Pierre (2013). Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages. 42nd Annual Scientific Meeting of ISEH - Society for Hematology and Stem Cells, Vienna, Austria, 22-25 August 2013. Philadelphia, PA United States: Elsevier Inc. doi: 10.1016/j.exphem.2013.05.230

Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages

Jacobsen, Rebecca, Pettit, Allison R., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Forristal, Catherine E., Winkler, Ingrid G. and Levesque, Jean-Pierre (2013). Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. WASHINGTON: AMER SOC HEMATOLOGY.

B Cells Do Not Influence Intramembranous Bone Modelling in Vivo

Pettit, A. R., Kaur, S., Alexander, K. A., MacDonald, K. P. A. and Raggatt, L. J. (2011). B Cells Do Not Influence Intramembranous Bone Modelling in Vivo. IOF Regionals 2nd Asia-Pacific Osteoporosis and Bone Meeting / ANZBMS Annual Scientific Meeting held with the JSBMR, Gold Coast, QLD Australia, 4-8 September 2011. London, United Kingdom: Springer.

Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis

Levesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

Jacobsen, RN, Levesque, JP, Barbier, V, Raggatt, LJ and Pettit, AR (2010). DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS. 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne AUSTRALIA, SEP 15-18, 2010. NEW YORK: ELSEVIER SCIENCE INC.

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

Levesque, J. P., Raggatt, L. J., Pettit, A. R., Sims, N. A., Bendall, L. J. and Helwani, F. (2009). Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. NEW YORK: ELSEVIER SCIENCE INC.

Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing

Alexander, K. A., Raggatt, L., Chang, M., Maylin, E., Muller, R., Kohler, T., Wu, A., Hume, D. and Pettit, A. (2009). Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, Colorado, USA, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.

Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing

Alexander, K. A., Raggatt, L. J., Chang, M. K., Maylin, E. R., Muller, R., Kohler, T., Wu, A. C. K., Hume, D. A. and Pettit, A. R. (2009). Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, NSW, Australia, 21-25 March 2009. United States: Elsevier. doi: 10.1016/j.bone.2009.01.076

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082

Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling

Raggatt, L., Chang, M., Alexander, K., Maylin, E., Walsh, N., Gravallese, E., Hume, D. and Pettit, A. (2009). Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, CO, United States, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.

Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling

Raggatt, L. J., Chang, M. K., Alexander, K. A., Maylin, E. R., Walsh, N. C., Gravallese, E. M., Hume, D. A. and Pettit, A. R. (2009). Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, Australia, 21-25 March, 2009. New York: Elsevier Science. doi: 10.1016/j.bone.2009.01.300

Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation

Chang, M. K., Pettit, A. R., Schroder, K., Ripoll, V. M., Alexander, K. A., Hume, D. A. and Raggatt, L. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation. ECTS 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, NY, U.S.A.: Springer New York. doi: 10.1007/s00223-008-9118-5

Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization

Alexander, K. A., Chang, M. K., Hume, D. A., Pettit, A. R., Raggatt, L., Ripoli, V. M. and Schroder, K. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization. 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, USA: Springer. doi: 10.1007/s00223-008-9118-5

Osteal Macrophages: Novel regulators of Bone Formation

Raggatt, L. J., Chang, M. K., Alexander, K. A., Kuiliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal Macrophages: Novel regulators of Bone Formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, 16th -19th September, 2007. Washington, D.C., United States: American Society for Bone and Mineral Research.

Osteal macrophages: Novel regulators of bone formation

Raggatt, L. J., Alexander, K. A., Kuliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal macrophages: Novel regulators of bone formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, United States, 16-19 September 2007.

Primary Murine Osteoblast Cultures Contain Macrophages that Enhance Osteoblast Mineralisation

Chang, M., Hume, D. A., Pettit, A. R., Raggatt, L., Ripoll, V. M. and Schroder, K. (2007). Primary Murine Osteoblast Cultures Contain Macrophages that Enhance Osteoblast Mineralisation. 29th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Honolulu, Hawaii, USA, 16th - 19th September, 2007. Washington, D. C.: American Society for Bone and Mineral Research.

The endosteal bone niche contains macrophages that regulate osteoblast function

Pettit, A. R., Chang, M. K., Alexander, K. A., Wu, A. C., Hume, D. A. and Raggatt, L. J. (2007). The endosteal bone niche contains macrophages that regulate osteoblast function. 17th Scientific Meeting of the International Bone & Mineral Society, Montreal, Canada, 24-29 June 2007. New York: Elsevier Science. doi: 10.1016/j.bone.2007.04.166

Tailoring poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for bone tissue engineering

Grondahl, L, Keen, I, Raggatt, L, Chandler-Temple, A. F., Cool, S M and Trau, M (2006). Tailoring poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for bone tissue engineering. 28th Australasian Polymer Symposium & Aust Society for Biomat, Rotorua, 5-9 Feb, 2006.

Parathyroid hormone stimulation of syndecan-4 in osteoblastic cells.

Raggatt, L. J., Qin, L., Cool, S., Nurcombe, V. and Partridge, N. (2005). Parathyroid hormone stimulation of syndecan-4 in osteoblastic cells.. 27th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Nashville, TN USA, 23-27 September 2005. Hoboken, NJ USA: Wiley-Blackwell Publishing.

Parathyroid hormone regulation of syndecan-4 in osteoblast cells

Raggatt, J. L., Qin, L., Cool, S. M., Nurcombe, V. and Partridge, N. C. (2005). Parathyroid hormone regulation of syndecan-4 in osteoblast cells. 27th Annual Meeting of the American Society for Bone and Mineral Research, Nashville, TN USA, 23-27 September 2005. Washington, DC USA: Wiley-Blackwell.

Parathyroid hormone stimulation of Syndecan-4 in osteoblastic cells

Raggatt, J. L., Qin, L., Cool, S. M., Nurcombe, V. and Partridge N. C. (2005). Parathyroid hormone stimulation of Syndecan-4 in osteoblastic cells. 27th Annual Meeting of the American Society for Bone and Mineral Research, Nashville, TN USA, 24-26 September, 2005. Malden, MA USA: American Society for Bone and Mineral Research.

Response of osteoblast cells to the surface properties of Poly(3-hydroxybutyrate-co-hydroxyvalerate) PHBV

Keen, I., Raggatt, L., Cool, S. M., Nurcombe, V., Fredericks, P., Trau, M. and Grondahl, L. (2005). Response of osteoblast cells to the surface properties of Poly(3-hydroxybutyrate-co-hydroxyvalerate) PHBV. 2nd ARC Centre For Functional Nanomaterials Annual Conference, Maroochydore, Nov, 2005.

Amphiregulin is a novel growth factor in bone stimulated by parathyroid hormone and required for normal bone development

Qin, L., Tamasi, J., Raggatt, L., Li, X., Feyen, J., Lee, D., DiCicco-Bloom, E. and Partridge, N. C. (2004). Amphiregulin is a novel growth factor in bone stimulated by parathyroid hormone and required for normal bone development. Annual Meeting of the American Society for Biochemistry-and-Molecular-Biology/8th Congress of the International Union for Biochemistry and Molecular Biology, Boston, MA, USA, 12-16 June 2004. Bethesda, MD, USA: Federation of American Societies for Experimental Biology.

Influence of solvent on the surface properties of PHBV solvent cast films

Keen, I., Grondahl, L., Raggatt, L., Fredericks, P.M., Nurcombe, V., Trau, M. and Cool, S. M. (2004). Influence of solvent on the surface properties of PHBV solvent cast films. 27th Australasian Polymer Symposium, Adelaide, Nov, 2004.

Amphiregulin: A possible mediator of parathyroid hormone's anabolic actions in bone.

Qin, L, Raggatt, L, Li, X, Tamasi, J, Feyen, JHM and Partridge, NC (2003). Amphiregulin: A possible mediator of parathyroid hormone's anabolic actions in bone.. 25th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Minneapolis Minnesota, Sep 19-23, 2003. WASHINGTON: AMER SOC BONE & MINERAL RES.

Parathyroid hormone stimulation of IL-18 in osteoblastic cells.

Raggatt, LJ, Qin, L and Partridge, NC (2003). Parathyroid hormone stimulation of IL-18 in osteoblastic cells.. 25th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Minneapolis Minnesota, Sep 19-23, 2003. WASHINGTON: AMER SOC BONE & MINERAL RES.

Amphiregulin: A possible mediator of parathyroid hormone's anabolic actions in bone

Qin, Ling, Raggatt, L., Li, X., Tamasi, J., Feyen, J. H. M. and Partridge, N. C. (2003). Amphiregulin: A possible mediator of parathyroid hormone's anabolic actions in bone. 25th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, Minnesota, U.S.A., 19-23 September, 2003. Washington, D.C., U.S.: American Society for Bone and Mineral Research.

Interaction of Collagenase-3 with its Specific Receptor and LRP-1

Choudhury, I., Williams, S., Raggatt, L. J, Byrne, M. H., Krane, S. M. and Partridge, N. C. (2003). Interaction of Collagenase-3 with its Specific Receptor and LRP-1. Experimental Biology 2003 Meeting, San Diego, California, USA, 11th - 15th April, 2003. Bethesda, MD: Federation of American Societies for Experimental Biology.

Parathyroid hormone stimulation of IL-18 gene expression in osteoblasts

Raggatt, Liza Jane, Qin, Ling and Partridge, Nicola (2003). Parathyroid hormone stimulation of IL-18 gene expression in osteoblasts. AAA Annual Meeting at Experimental Biology 2003, San Diego, CA, U.S.A., 11-15 April 2003. Bethesda, MD, U.S.A.: Federation of American Societies for Experimental Biology.

Parathyroid hormone stimulation of IL-18 in osteoblastic cells

Raggatt, L. J., Qin, L. and Partridge, N. C. (2003). Parathyroid hormone stimulation of IL-18 in osteoblastic cells. 25th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, U.S., 19-23 September, 2003. Washington, D.C., U.S.: American Society for Bone and Mineral Research.

Characterization of collagenase-3 binding and internalization by rabbit chondrocytes.

Raggatt, LJ, Choudhury, I, Williams, S, Tiku, ML and Partridge, NC (2002). Characterization of collagenase-3 binding and internalization by rabbit chondrocytes.. 24th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, San Antonio Texas, Sep 20-24, 2002. WASHINGTON: AMER SOC BONE & MINERAL RES.

Characterization of collagenase-3 binding to the collagenase-3 specific receptor and LRP1.

Choudhury, I, Williams, S, Raggatt, LJ, Byrne, MH, Krane, SM and Partridge, NC (2002). Characterization of collagenase-3 binding to the collagenase-3 specific receptor and LRP1.. 24th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, San Antonio Texas, Sep 20-24, 2002. WASHINGTON: AMER SOC BONE & MINERAL RES.

Characterization of Collagenase-3 Binding and Internalization by Rabbit Chondrocytes

Raggatt, L. J., Choudhury, I., Williams, S., Tiku ,M. L. and Partridge, N. C. (2002). Characterization of Collagenase-3 Binding and Internalization by Rabbit Chondrocytes. 24th Annual Meeting of the American Society for Bone and Mineral Research, San Antonio, Texas, USA, 20th - 24th September, 2002. Washington, D. C.: American Society for Bone and Mineral Research.

Characterization of Collagenase-3 Binding to the Collagenase-3 Specific Receptor and LRP1

Choudhury, I., Williams, S., Raggatt, L. J., Byrne, M. H., Krane, S. M. and Partridge, N. C (2002). Characterization of Collagenase-3 Binding to the Collagenase-3 Specific Receptor and LRP1. 24th Annual Meeting of the American Society for Bone and Mineral Research, San Antonio, Texas, USA, 20th - 24th September, 2002. Washington, D. C.: American Society for Bone and Mineral Research.

Activation of the insert negative human calcitonin receptor: Phosphorylation of MAP kinase and inhibition of cellular proliferation.

Raggatt, LJ, Evdokiou, A and Findlay, DM (1999). Activation of the insert negative human calcitonin receptor: Phosphorylation of MAP kinase and inhibition of cellular proliferation.. DURHAM: AMER SOC BONE & MINERAL RES.

Growth inhibition by calcitonin of HEK293 cells is accompanied by induction of p21/WAF1/CIP1 and G2/M arrest

Evdokiou, A, Raggatt, L, Atkins, GJ and Findlay, DM (1998). Growth inhibition by calcitonin of HEK293 cells is accompanied by induction of p21/WAF1/CIP1 and G2/M arrest. BETHESDA: AMER SOC CELL BIOLOGY.