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Trapping and Watching Biomolecular Complexes near Nanopores (2016–2018)

Abstract:
Our investigators have recently developed the first prototype of a highly innovative methodology to trap and interrogate nano-scaled objects as small as 190 nm within a nanopore device. By performing research to fully understand, miniaturise and develop this method further, this project aims to enable the quantitative observation of nano-scaled biological machinery involved in cell-to-cell communication and DNA unfolding. Given the extremely broad applications of such a generic technology platform capable of interrogating individual objects in the 1-1000 nm size range, this project aims to have a transformative effect in areas as diverse as biology, biotechnology and advanced materials.
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Matt Trau

    ARC Australian Laureate Fellow
    Australian Institute for Bioengineering and Nanotechnology
    ARC Laureate Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council