Dr Andy Moore

ATH - Associate Professor

Child Health Research Centre
Faculty of Medicine

Overview

Associate Professor Andy Moore is a Paediatric Oncologist and Director of Research at Children's Health Queensland Hospital & Health Service (CHQ). He is also Director of the Queensland Children's Tumour Bank, which is part of UQ's Child Health Research Centre. The Queensland Children's Tumour Bank is a unique resource located on the Queensland Children's Hospital precinct, facilitating local, national and international collaborative research across all childhood cancer types. Dr Moore's clinical and research interests focus on childhood leukaemia, particularly acute myeloid leukaemia (AML), an aggressive form of leukaemia with a poor prognosis.

Research Interests

  • Acute Myeloid Leukaemia
  • Leukaemia
  • Blood Cancers
  • Paediatric Oncology
  • Childhood Cancer
  • Biobanking

Qualifications

  • Doctor of Philosophy, University of London
  • Bachelor of Medicine & Bachelor of Surgery, The University of Queensland

Publications

  • Yeoh, Daniel K., Moore, Andrew S., Kotecha, Rishi S., Bartlett, Adam W., Ryan, Anne L., Cann, Megan P., McMullan, Brendan J., Thursky, Karin, Slavin, Monica, Blyth, Christopher C., Haeusler, Gabrielle M. and Clark, Julia E. (2021). Invasive fungal disease in children with acute myeloid leukaemia: an Australian multicentre 10‐year review. Pediatric Blood and Cancer, e29275. doi: 10.1002/pbc.29275

  • Ferretti, Roberta, Baldassarre, Antonella, Billy, Emmanuel de, M Carcaboso, Angel, Moore, Andrew, Carai, Andrea, Mastronuzzi, Angela, Masotti, Andrea and Vinci, Maria (2021). Tumor cell invasion into Matrigel: optimized protocol for RNA extraction. BioTechniques, 70 (6), 327-335. doi: 10.2144/btn-2021-0001

  • Wong, Marie, Mayoh, Chelsea, Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Pinese, Mark, Kumar, Amit, Barahona, Paulette, Wilkie, Emilie E., Sullivan, Patricia, Bowen-James, Rachel, Syed, Mustafa, Martincorena, Iñigo, Abascal, Federico, Sherstyuk, Alexandra, Bolanos, Noemi A., Baber, Jonathan, Priestley, Peter, Dolman, M. Emmy M., Fleuren, Emmy D. G., Gauthier, Marie-Emilie, Mould, Emily V. A., Gayevskiy, Velimir, Gifford, Andrew J., Grebert-Wade, Dylan, Strong, Patrick A., Manouvrier, Elodie, Warby, Meera, Thomas, David M., Kirk, Judy ... Cowley, Mark J. (2020). Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer. Nature Medicine, 26 (11), 1742-1753. doi: 10.1038/s41591-020-1072-4

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Grants

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Supervision

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Publications

Journal Article

Conference Publication

  • Pericoli, Giulia, Galardi, Angela, Petrilli, Lucia Lisa, Colletti, Marta, Ferretti, Roberta, Paolini, Alessandro, Masotti, Andrea, Mortera, Stefano Levi, Petrini, Stefania, de Billy, Emmanuel, Pascucci, Luisa, Court, Will, Cacchione, Antonella, Carai, Andrea, Camassei, Francesca Diomedi, Moore, Andrew, Carcaboso, Angel Montero, Jones, Chris, Mastronuzzi, Angela, Locatelli, Franco, Di Giannatale, Angela and Vinci, Maria (2018). Diffuse intrinsic pontine glioma and pediatric glioblastoma derived-exosomes have specific oncogenic signatures. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, LA, United States, 14-18 November 2018. Cary, NC, United States: Oxford University Press.

  • Bjerke, Lynn, Mackay, Alan, Carvalho, Diana, Pemberton, Helen, Molinari, Valeria, Vinci, Maria, Carceller, Fernando, Marshall, Lynley, Moore, Andrew, Montero Carcaboso, Angel, Lord, Chris, Hargrave, Darren and Jones, Chris (2018). Targeting H3.3G34R/V re-wiring of the epigenome in paediatric glioblastoma of children and young adults. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, United States, 14-18 November, 2018. Cary, NC, United States: Oxford University Press.

  • Zhang, Christine R. C., Afrin, Sadia, Maybury, Mellissa, Pham, Thy, Fink, Lynn and Moore, Andrew S. (2018). Aberrant splicing of KMT2A as a potential molecular MRD marker in cytogenetically-normal AML. 60th Annual Meeting of the American Society of Hematology (ASH), San Diego, CA USA, 1-4 December 2018. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2018-99-117759

  • Afrin, Sadia, Zhang, Christine R. C., Meyer, Claus, Maybury, Mellissa, Pham, Thy, Venn, Nicola, Trahair, Toby N., Sutton, Rosemary, Marschalek, Rolf, Fink, Lynn and Moore, Andrew S. (2018). Quantitative analysis of MLL fusion transcripts by droplet digital PCR to monitor minimal residual disease in MLL-rearranged acute myeloid leukemia. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA USA, 1-4 December 2018. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2018-99-117761

  • Clarke, M. T., Jones, D., Carvalho, D. M., Mackay, A., Izquierdo, E., Hargrave, D., Moore, A. S., Popov, S., Jacques, T. S. and Jones, C. (2018). The Molecular Pathology of Infant Gliomas. Winter Meeting on Epigenetics - Understanding Disease and Guiding Therapies / Joint Meeting of the Royal-Society-of-Medicine / 209th Scientific Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Marylebone England, 25-26 January 2018. Hoboken, NJ United States: Wiley.

  • Clarke, M., Jones, D. T. W., Carvalho, D., Mackay, A., Izquierdo, E., Hargrave, D., Moore, A. S., Popov, S., Jacques, T. and Jones, C. (2018). The molecular pathology of infant gliomas. 119th Meeting of the British-Neuropathological-Society (BNS) / Epilepsy Neuropathology Symposium, London England, Feb 28-Mar 02 2018. Hoboken, NJ United States: Wiley.

  • Hennig, S., Kunarajah, K., Norris, R., Lobb, M., Charles, B., Pinkerton, R. and Moore, A. S. (2016). A pilot study to investigate the relationship between doxorubicin and doxorubicinol pharmacokinetics and cardiotoxicity in children and adolescents with cancer.. World Conference of Pharmacometrics, Brisbane / Brisbane Convention Centre, 21-24 August 2016.

  • Hahn, Christopher N., Babic, Milena, Schreiber, Andreas W., Kutyna, Monika M., Wee, L. Amilia, Brown, Anna L., Perugini, Michelle, Singhal, Deepak, Hiwase, Smita, Feng, Jinghua, Parker, Wendy T., Moore, Sarah, Bardy, Peter G., Saal, Russell, Marlton, Paula, Moore, Andrew S., Gonda, Thomas J., Leo, Paul, Branford, Susan, DAndrea, Richard J., Lewis, Ian D., Bik, Luen, Scott, Harnish S. and Hiwase, Devendra (2015). Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome. 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, United States, 5-8 December 2015. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood.V126.23.1644.1644

  • Bruedigam, Claudia, Bagger, Frederik Otzen, Heidel, Florian H., Kuhn, Catherine, Guignes, Solene, Song, Axia, Austin, Rebecca, Vu, Therese, Lee, Erwin M., Moore, Andrew S., Lock, Richard B., Bullinger, Lars, Hill, Geoff R. and Lane, Steven W. (2014). Inhibition of Telomerase with Imetelstat Is Detrimental to Leukemia Stem Cells in Acute Myeloid Leukemia (AML). 56th Annual Meeting of the American Society of Hematology, San Francisco CA, United States, 06-09 December 2014. Washington, DC United States: American Society of Hematology.

  • Lobb, M., Norris, R. L. G., Charles, B., Gilshenan, K., Moore, A. and Pinkerton, R. (2011). Blood collection technique for pharmacokinetic studies of doxorubicin in paediatric patients. 12th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Stuttgart, Germany, 2-6 October, 2011. Philadelphia PA, United States: Lippincott Wiliams & Wilkins. doi: 10.1097/01.ftd.0000400651.94145.ba

  • Moore, AS, Faisal, A, Bavetsias, V, de Castro, DG, Sun, CB, Atrash, B, Valenti, M, Brandon, AD, Avery, S, Pearson, ADJ, Workman, P, Blagg, J, Raynaud, FI, Eccles, SA and Linardopoulos, S (2011). Resistance to Selective FLT3 Inhibitors, Driven by FLT3 Ligand and FLT3 Point Mutations, Can Be Overcome with the Dual FLT3-Aurora Kinase Inhibitor CCT241736. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego CA, DEC 10-13, 2011.

  • Podesta, JE, Griffin, MJ, Sugar, R, Squires, MS, Boddy, A, Linardopoulos, S, Pearson, ADJ and Moore, AS (2010). Adaptation and Validation of the Plasma Inhibitory Activity (PIA) Assay to Detect Inhibition of Aurora, ABL and FLT3 kinases by AT9283 In Children and Adolescents with Leukaemia.. 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando FL, DEC 04-07, 2010.

  • Moore, AS, Faisal, A, Bavetsias, V, Sun, CB, Atrash, B, Valenti, M, Brandon, AD, Avery, S, Raynaud, FI, Workman, P, Pearson, ADJ, Blagg, J, Eccles, SA and Linardopoulos, S (2010). Dual Inhibition of Aurora and FLT3 Kinases by CCT137690: A Novel Treatment Strategy Against FLT3-ITD Positive AML In Vitro and In Vivo. 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando FL, DEC 04-07, 2010.

  • Moore, A.S. and Hallahan, A.R. (2008). Use of etanercept in children following haematopoietic stem cell transplantation: a single institution experience. 48th Annual Scientific Meeting of the British Society for Haematology, Glasgow, Scotland, 7-9 April 2008. United Kingdom: Wiley-Blackwell Publishing Ltd.. doi: 10.1111/j.1365-2141.2008.07061.x

  • Moore, Andrew, Charles, Bruce, Wilkinson, Catherine, Weier, Steven and Pinkerton, Ross (2007). Does myelosuppression during consolidation or high-dose methotrexate clearance correlate with tolerance of initial maintenance therapy in childhood acute lymphoblastic leukaemia?. 39th Annual Conference of the International Society of Paediatric Oncology SIOP 2007, Mumbai, India, 31 October-3 November 2007. Hoboken: Wiley-Liss, Inc. doi: 10.1002/pbc.21342

Grants (Administered at UQ)

PhD and MPhil Supervision

Note for students: Dr Andy Moore is not currently available to take on new students.

Completed Supervision