Professor Sunil Lakhani

Head, Discipline of Pathology

UQ Centre for Clinical Research
Faculty of Medicine
s.lakhani@uq.edu.au
+61 7 334 66052

Overview

Sunil Lakhani is Head of Molecular & Cellular Pathology in The School of Medicine, University of Queensland, State Director, Anatomical Pathology, Pathology Queensland, and Head of the Breast Group at the University of Queensland Centre for Clinical Research (UQCCR) at the Royal Brisbane and Women’s Hospital.

Prior to his move to Australia in 2004, he was Professor of Breast Pathology at The Institute of Cancer Research and The Royal Marsden Hospital, London, UK

His current research interests include lobular carcinoma and its variants, normal and stem cells, tumours with a basal phenotype, mechanisms of brain and distant metastases and familial breast cancer.

He is a series editor for the WHO Tumour Classification Books and volume editor for the WHO Classification of Tumours of the Breast. He is on the editorial board of a number of pathology and experimental research journals.

Research Impacts

The recognition that ADH is biologically very similar to DCIS has led to a policy of excising all ADH lesions diagnosed on core biopsies at breast screening assessment

The demonstration that LCIS is a clonal neoplastic proliferation with the same molecular phenotype as invasive lobular carcinoma, and the subsequent dissemination of this knowledge through publication (Lakhani SR 2003, Lancet) and conference presentations has also changed the management of LCIS. It is accepted that it is a non-obligate precursor, rather than a hyperplastic lesion.

The recognition of the pleomorphic variant of lobular is now changing the way this proliferation is managed. Like other lobular lesions, it is multifocal/bilateral but a more aggressive variant. There is considerable ongoing discussion on the international stage regarding management and my work has played a role in this policy change.

We have also shown that columnar cell lesions, which are increasingly being diagnosed in the screening program, are clonal lesions with a progressive relationship to low grade DCIS (Simpson PT et al 2005 Am J Surg Pathol). We have shown that morphological atypia is associated with molecular profiles similar to that of DCIS and hence patients with atypical lesions on core biopsy are now subjected to further excision. It has been shown subsequently that many of these patients have worse pathology on further resection.

My expertise, in diagnostic and molecular biology of pre-invasive breast disease has also been acknowledged in being appointed Head of Breast Screen Pathology, North Brisbane as well as being a member of the Breast Screen Quality (‘Q’) group in Queensland.

My work as part of the BCLC has demonstrated that BRCA1-related breast cancers are high grade, highly proliferative tumours and occurred in young women. Hence there was an immediate impact on breast screening protocols. I was invited to many meetings to discuss the pathology in relation to the following: (i) should mammography be used in young women and how effective would it be in dense breasts? (ii) should another modality such as MRI be considered? (iii) irrespective of the modality, should the screening interval be shortened to reduce the risk that patients would present with interval cancers?

All these issues have been addressed subsequent to the publications – in particular, I was member of the steering group that published the experience of using MRI in young women at high risk of breast cancer (Leach et al 2005 MARIBS The Lancet). MRI is now used in many countries to screen high-risk women. The screening interval has been reduced to 1 year as many patients did present with interval cancers as predicted by the pathology.

In extending the original work on morphology, my group has also demonstrated that a large proportion of BRCA1associated cancers are ER negative and ‘basal-like’. This led us to propose that this phenotype could be used to improve the risk estimation and carrier probability of women seen in family cancer clinics (Lakhani et al 2005 Clin Can Res).

We have now published a number of papers supporting the use of pathology data to improve risk estimation as well as improving the likelihood of unclassified variants (UVs) being pathogenic. This work has been done with previous BCLC collaborators (Prof Doug Easton) as well as with Georgia Chenevix-Trench and Amanda Spurdle at QIMR (Chenevix-Trench et al 2006 Can Res, Lovelock et al 2007 Br Can Res, Spurdle et al 2008 JCO, Spurdle et al 2009 Hum Mut, Mavaddat et al 2010 Br Can Res) This approach is now being incorporated into the genetics clinics.

Qualifications

  • Fellow of Royal College of Pathologists
  • Doctor of Medicine, University of London
  • Bachelor of Medicine Bachelor of Surgery, University of London
  • Bachelor of Science (hons), University of London

Publications

  • Saunus, Jodi M., Smart, Chanel E., Kutasovic, Jamie R., Johnston, Rebecca L., Kalita-de Croft, Priyakshi, Miranda, Mariska, Rozali, Esdy N., Vargas, Ana Cristina, Reid, Lynne E., Lorsy, Eva, Cocciardi, Sibylle, Seidens, Tatjana, McCart Reed, Amy E., Dalley, Andrew J., Wockner, Leesa F., Johnson, Julie, Sarkar, Debina, Askarian-Amiri, Marjan E., Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia, Al-Ejeh, Fares and Lakhani, Sunil R. (2017) Multidimensional phenotyping of breast cancer cell lines to guide preclinical research. Breast Cancer Research and Treatment, 1-13. doi:10.1007/s10549-017-4496-x

  • Hendry, Shona, Salgado, Roberto, Gevaert, Thomas, Russell, Prudence A., John, Tom, Thapa, Bibhusal, Christie, Michael, van de Vijver, Koen, Estrada, M. V, Gonzalez-Ericsson, Paula I, Sanders, Melinda, Solomon, Benjamin sss, Solinas, Cinzia, Van den Eynden, Gert G. G. M., Allory, Yves, Preusser, Matthias, Hainfellner, Johannes, Pruneri, Giancarlo, Vingiani, Andrea, Demaria, Sandra, Symmans, Fraser, Nuciforo, Paolo, Comerma, Laura, Thompson, E. A., Lakhani, Sunil, Kim, Seong-Rim, Schnitt, Stuart, Colpaert, Cecile, Sotiriou, Christos, Scherer, Stefan J., Ignatiadis, Michail, Badve, Sunil, Pierce, Robert H., Viale, Giuseppe, Sirtaine, Nicolas, Penault-Llorca, Frederique, Sugie, Tomohagu, Fineberg, Susan, Paik, Soonmyung, Srinivasan, Ashok, Richardson, Andrea, Wang, Yihong, Chmielik, Ewa, Brock, Jane, Johnson, Douglas B., Balko, Justin, Wienert, Stephan, Bossuyt, Veerle, Michiels, Stefan, Ternes, Nils, Burchardi, Nicole, Luen, Stephen J., Savas, Peter, Klauschen, Frederick, Watson, Peter H., Nelson, Brad H., Criscitiello, Carmen, O'Toole, Sandra, Larsimont, Denis, de Wind, Roland, Curigliano, Giuseppe, Andre, Fabrice, Lacroix-Triki, Magali, van de Vijver, Mark, Rojo, Federico, Floris, Giuseppe, Bedri, Shahinaz, Sparano, Joseph, Rimm, David, Nielsen, Torsten, Kos, Zuzana, Hewitt, Stephen, Singh, Baljit, Farshid, Gelareh, Loibl, Sibylle, Allison, Kimberly H., Tung, Nadine, Adams, Sylvia, Willard-Gallo, Karen, Horlings, Hugo M., Gandhi, Leena, Moreira, Andre, Hirsch, Fred, Dieci, Maria V., Urbanowicz, Maria, Brcic, Iva, Korski, Konstanty, Gaire, Fabien, Koeppen, Hartmut, Lo, Amy, Giltnane, Jennifer, Rebelatto, Marlon C., Steele, Keith E., Zha, Jiping, Emancipator, Kenneth, Juco, Jonathan W., Denkert, Carsten, Reis-Filho, Jorge, Loi, Sherene and Fox, Stephen B. (2017) Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immunooncology Biomarkers Working Group: Part 1: assessing the host immune response, TILs in invasive breast carcinoma and ductal carcinoma in situ, metastatic tumor deposits and areas for further research. Advances in Anatomic Pathology, 24 5: 235-251. doi:10.1097/PAP.0000000000000162

  • Hendry, Shona, Pang, Jia-Min B., Byrne, David J., Lakhani, Sunil R., Cummings, Margaret C., Campbell, Ian G., Mann, G. Bruce, Gorringe, Kylie L. and Fox, Stephen B. (2017) Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features. Clinical Cancer Research, 23 17: 5210-5217. doi:10.1158/1078-0432.CCR-17-0743

View all Publications

Supervision

View all Supervision

Publications

Book Chapter

  • Smith, Deborah, McCart Reed, Amy and Lakhani, Sunil R. (2017). Forgotten resources – the autopsy. In Sunil R. Lakhani and Stephen B. Fox (Ed.), Molecular pathology in cancer research (pp. 335-348) New York, NY, United States: Springer. doi:10.1007/978-1-4939-6643-1

  • Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. In Sandra J. Shin (Ed.), A comprehensive guide to core needle biopsies of the breast (pp. 803-817) Cham, Switzerland: Springer. doi:10.1007/978-3-319-26291-8

  • Schnitt, Stuart J. and Lakhani, Sunil S. (2014). Breast Cancer. In Bernard W. Stewart and Christopher P. Wild (Ed.), World Cancer Report (pp. 362-373) Lyon, France: IARC.

  • Saunus, Jodi M., McCart-Reed, Amy, Momeny, Majid, Cummings, Margaret and Lakhani, Sunil R. (2013). Breast cancer heterogeneity in primary and metastatic disease. In Aamir Ahmad (Ed.), Breast Cancer Metastasis and Drug Resistance: Challenges and Progress (pp. 65-96) New York, NY, USA: Springer. doi:10.1007/978-1-4614-5647-6

  • Schnitt, S., Collins, L., Lakhani, S. R. and Simpson, P. T. (2012). Flat epithelial atypia. In WHO Classification of Tumours of the Breast 4th ed. (pp. 87-87) Lyon, France: IARC Press.

  • Lakhani, S. R., Rakha, E. and Simpson, P. T. (2012). Invasive lobular carcinoma. In WHO classification of tumours of the breast 4th ed. (pp. 40-42) Lyon, France: IARC Press.

  • Lakhani, S. R., Schnitt, S., O’Malley, F., van de Vijver, M., Simpson, P. T. and Palacios, J. (2012). Lobular neoplasia. In WHO classification of tumours of the breast 4th ed. (pp. 77-80) Lyon, France: IARC Press.

  • Smart, Chanel, Simpson, Peter T., Vargas, Ana Cristina and Lakhani, Sunil R. (2011). Genetic alterations in normal and malignant breast tissue. In Tot, Tibor (Ed.), Breast cancer, a lobar disease 1st Edition ed. (pp. 53-66) London, United Kingdom: Springer. doi:10.1007/978-1-84996-314-5_4

  • Smart, Chanel E., Furnival, Colin M. and Lakhani, Sunil R. (2010). High-risk lesions: ALH/LCIS/ADH. In Henry Mark Kuerer (Ed.), Kuerer's breast surgical oncology (pp. 179-187) New York, U.S.A.: McGraw-Hill Medical.

  • Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ. In Ismail Jatoi and M. Kaufmann (Ed.), Management of breast diseases (pp. 181-199) Heidelberg: Springer. doi:10.1007/978-3-540-69743-5_11

  • Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ : Biology and pathology. In Jay R. Harris, Marc E. Lippman, C. Kent Osborne and Monica Morrow (Ed.), Diseases of the breast 4th ed. (pp. 333-340) Philadelphia: Lippencott, Williams & Wilkins.

  • Penault-Llorca, F. and Lakhani, S. R. (2007). Pathology of ovarian tumors in mutation carriers. In Isaacs, C. and Rebbeck, T. R. (Ed.), Hereditary Breast Cancer (pp. 333-343) New York, U.S.A.: Informa Healthcare.

  • Jones, Chris, Simpson, Peter, Mackay, Alan and Lakhani, Sunil R. (2006). Expression profiling using cDNA microarrays. In Susan A. Brooks and Adrian Harris (Ed.), Breast cancer research protocols (pp. 403-414) Totowa, NJ, U.S.A.: Humana Press. doi:10.1385/1-59259-969-9:403

  • Simpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R. (2006). Gene expression analysis using filter cDNA microarrays. In Susan A. Brooks and Adrian Harris (Ed.), Breast cancer research protocols (pp. 415-424) Totowa, USA: Humana Press.

  • Reis-Filho, J.S. and Lakhani, S.R. (2006). Molecular genetics of ADH/DCIS and ALH/LCIS. In Goldblum, J.R. (Ed.), Breast Pathology (pp. 185-189) Philadelphia, U.S.A.: Churchill Livingstone.

  • Jones, Chris and Lakhani , Sunil R. (2006). Molecular investigation of breast disease. In G. Querci della Rovere, R. Warren and John R. Benson (Ed.), Early breast cancer: From screening to multidisciplinary management 2nd ed. (pp. 319-327) London, U.K. ; New York, U.S.A.: Informa Healthcare.

  • Fulford, Laura G., Reis-Filho, Jorge S. and Lakhani, Sunni R. (2004). Lobular carcinoma in situ: Biology and pathology. In Jay R. Harris, Marc E. Lippman, Monica Morrow and C. Kent Osborne (Ed.), Diseases of the breast 3rd ed. (pp. 489-495) Philadelphia, U.S.A.: Lippincott Williams & Wilkins.

  • Lakhani, Sunil and Dogan, A. (2004). Wound Healing. In Kirk, R.M. and Ribbans, W. J. (Ed.), Clinical surgery in general : RCS course manual 4th ed. (pp. 322-330) Edinburgh; New York: Churchill Livingstone.

Journal Article

  • Saunus, Jodi M., Smart, Chanel E., Kutasovic, Jamie R., Johnston, Rebecca L., Kalita-de Croft, Priyakshi, Miranda, Mariska, Rozali, Esdy N., Vargas, Ana Cristina, Reid, Lynne E., Lorsy, Eva, Cocciardi, Sibylle, Seidens, Tatjana, McCart Reed, Amy E., Dalley, Andrew J., Wockner, Leesa F., Johnson, Julie, Sarkar, Debina, Askarian-Amiri, Marjan E., Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia, Al-Ejeh, Fares and Lakhani, Sunil R. (2017) Multidimensional phenotyping of breast cancer cell lines to guide preclinical research. Breast Cancer Research and Treatment, 1-13. doi:10.1007/s10549-017-4496-x

  • Hendry, Shona, Salgado, Roberto, Gevaert, Thomas, Russell, Prudence A., John, Tom, Thapa, Bibhusal, Christie, Michael, van de Vijver, Koen, Estrada, M. V, Gonzalez-Ericsson, Paula I, Sanders, Melinda, Solomon, Benjamin sss, Solinas, Cinzia, Van den Eynden, Gert G. G. M., Allory, Yves, Preusser, Matthias, Hainfellner, Johannes, Pruneri, Giancarlo, Vingiani, Andrea, Demaria, Sandra, Symmans, Fraser, Nuciforo, Paolo, Comerma, Laura, Thompson, E. A., Lakhani, Sunil, Kim, Seong-Rim, Schnitt, Stuart, Colpaert, Cecile, Sotiriou, Christos, Scherer, Stefan J., Ignatiadis, Michail, Badve, Sunil, Pierce, Robert H., Viale, Giuseppe, Sirtaine, Nicolas, Penault-Llorca, Frederique, Sugie, Tomohagu, Fineberg, Susan, Paik, Soonmyung, Srinivasan, Ashok, Richardson, Andrea, Wang, Yihong, Chmielik, Ewa, Brock, Jane, Johnson, Douglas B., Balko, Justin, Wienert, Stephan, Bossuyt, Veerle, Michiels, Stefan, Ternes, Nils, Burchardi, Nicole, Luen, Stephen J., Savas, Peter, Klauschen, Frederick, Watson, Peter H., Nelson, Brad H., Criscitiello, Carmen, O'Toole, Sandra, Larsimont, Denis, de Wind, Roland, Curigliano, Giuseppe, Andre, Fabrice, Lacroix-Triki, Magali, van de Vijver, Mark, Rojo, Federico, Floris, Giuseppe, Bedri, Shahinaz, Sparano, Joseph, Rimm, David, Nielsen, Torsten, Kos, Zuzana, Hewitt, Stephen, Singh, Baljit, Farshid, Gelareh, Loibl, Sibylle, Allison, Kimberly H., Tung, Nadine, Adams, Sylvia, Willard-Gallo, Karen, Horlings, Hugo M., Gandhi, Leena, Moreira, Andre, Hirsch, Fred, Dieci, Maria V., Urbanowicz, Maria, Brcic, Iva, Korski, Konstanty, Gaire, Fabien, Koeppen, Hartmut, Lo, Amy, Giltnane, Jennifer, Rebelatto, Marlon C., Steele, Keith E., Zha, Jiping, Emancipator, Kenneth, Juco, Jonathan W., Denkert, Carsten, Reis-Filho, Jorge, Loi, Sherene and Fox, Stephen B. (2017) Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immunooncology Biomarkers Working Group: Part 1: assessing the host immune response, TILs in invasive breast carcinoma and ductal carcinoma in situ, metastatic tumor deposits and areas for further research. Advances in Anatomic Pathology, 24 5: 235-251. doi:10.1097/PAP.0000000000000162

  • Hendry, Shona, Pang, Jia-Min B., Byrne, David J., Lakhani, Sunil R., Cummings, Margaret C., Campbell, Ian G., Mann, G. Bruce, Gorringe, Kylie L. and Fox, Stephen B. (2017) Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features. Clinical Cancer Research, 23 17: 5210-5217. doi:10.1158/1078-0432.CCR-17-0743

  • Fielding, David, Dalley, Andrew J., Bashirzadeh, Farzad, Singh, Mahendra, Nandakumar, Lakshmy, Reed, Amy E. McCart, Black, Debra, Kazakoff, Stephen, Nones, Katia, Pearson, John, Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2017) Next-generation sequencing of endobronchial ultrasound transbronchial needle aspiration specimens in lung cancer. American Journal of Respiratory and Critical Care Medicine, 196 3: 388-391. doi:10.1164/rccm.201609-1935LE

  • Pang, Jia-Min B., Savas, Peter, Fellowes, Andrew P., Arnau, Gisela Mir, Kader, Tanjina, Vedururu, Ravikiran, Hewitt, Chelsee, Takano, Elena A., Byrne, David J., hoong, David Y. H., Millar, Ewan K. A., Lee, C. Soon, O'Toole, Sandra A., Lakhani, Sunil R., Cummings, Margaret C., Mann, G. Bruce, Campbell, Ian G., Dobrovic, Alexander, Loi, Sherene, Gorringe, Kylie L. and Fox, Stephen B. (2017) Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer. Modern Pathology, 30 7: 952-963. doi:10.1038/modpathol.2017.21

  • Davies, Helen, Glodzik, Dominik, Morganella, Sandro, Yates, Lucy R., Staaf, Johan, Zou, Xueqing, Ramakrishna, Manasa, Martin, Sancha, Boyault, Sandrine, Sieuwerts, Anieta M., Simpson, Peter T., King, Tari A., Raine, Keiran, Eyfjord, Jorunn E., Kong, Gu, Borg, Åke, Birney, Ewan, Stunnenberg, Hendrik G., Van De Vijver, Marc J., Borresen-Dale, Anne-Lise, Martens, John W. M., Span, Paul N., Lakhani, Sunil R., Vincent-Salomon, Anne, Sotiriou, Christos, Tutt, Andrew, Thompson, Alastair M., Van Laere, Steven, Richardson, Andrea L., Viari, Alain, Campbell, Peter J., Stratton, Michael R. and Nik-Zainal, Serena (2017) HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nature Medicine, 23 4: 517-525. doi:10.1038/nm.4292

  • Koteeswaran, Rajasekaran, Simpson, Peter, Bartle, Emma, Smith, Deborah, Bhutada, Ekta, Ayre, Julie and Lakhani, Sunil R. (2017) Flipping pathology: our experience at an Australian medical school. Medical Science Educator, . doi:10.1007/s40670-017-0406-4

  • Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B., Rahbari, Raheleh, Wedge, David C., Davies, Helen R., Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, Alder, Christopher, Patel, Nikita, Gamble, Steve, O'Meara, Sarah, Giri, Dilip D., Sauer, Torril, Pinder, Sarah E., Purdie, Colin A., Borg, Ake, Stunnenberg, Henk, van de Vijver, Marc, Tan, Benita K. T., Caldas, Carlos, Tutt, Andrew, Ueno, Naoto T., van't Veer, Laura J., Martens, John W. M., Sotiriou, Christos, Knappskog, Stian, Span, Paul N., Lakhani, Sunil R., Eyfjord, Jorunn Erla, Borresen-Dale, Anne-Lise, Richardson, Andrea, Thompson, Alastair M., Viari, Alain, Hurles, Matthew E., Nik-Zainal, Serena, Campbell, Peter J. and Stratton, Michael R. (2017) Somatic mutations reveal asymmetric cellular dynamics in the early human embryo. Nature, 543 7647: 714-718. doi:10.1038/nature21703

  • Glodzik, Dominik, Morganella, Sandro, Davies, Helen, Simpson, Peter T., Li, Yilong, Zou, Xueqing, Diez-Perez, Javier, Staaf, Johan, Alexandrov, Ludmil B., Smid, Marcel, Brinkman, Arie B., Rye, Inga Hansine, Russnes, Hege, Raine, Keiran, Purdie, Colin A., Lakhani, Sunil R., Thompson, Alastair M., Birney, Ewan, Stunnenberg, Hendrik G., Van De Vijver, Marc J., Martens, John W. M., Borresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Viari, Alain, Easton, Douglas, Evan, Gerard, Campbell, Peter J., Stratton, Michael R. and Nik-Zainal, Serena (2017) A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nature Genetics, 49 3: 341-348. doi:10.1038/ng.3771

  • Dahlstrom, Jane E., Rakha, Emad A., Lakhani, Sunil R. and Schnitt, Stuart J. (2017) Current topics in breast pathology: expert perspectives. Pathology, 49 2: 109-110. doi:10.1016/j.pathol.2016.12.001

  • Simmons, Alex, Burrage, Pamela M., Nicolau, Dan V., Lakhani, Sunil R. and Burrage, Kevin (2017) Environmental factors in breast cancer invasion: a mathematical modelling review. Pathology, 49 2: 172-180. doi:10.1016/j.pathol.2016.11.004

  • Saunus, Jodi M., McCart Reed, Amy E., Lim, Zhun Leong and Lakhani, Sunil R. (2017) Breast cancer brain metastases: clonal evolution in clinical context. International Journal of Molecular Sciences, 18 1: . doi:10.3390/ijms18010152

  • Kalita-De Croft, Priyakshi, Al-Ejeh, Fares, McCart Reed, Amy E., Saunus, Jodi M. and Lakhani, Sunil R. (2016) 'Omics approaches in breast cancer research and clinical practice. Advances in Anatomic Pathology, 23 6: 356-367. doi:10.1097/PAP.0000000000000128

  • Denkert, Carsten, Wienert, Stephan, Poterie, Audrey, Loibl, Sibylle, Budczies, Jan, Badve, Sunil, Bago-Horvath, Zsuzsanna, Bane, Anita, Bedri, Shahinaz, Brock, Jane, Chmielik, Ewa, Christgen, Matthias, Colpaert, Cecile, Demaria, Sandra, Van Den Eynden, Gert, Floris, Giuseppe, Fox, Stephen B., Gao, Dongxia, Ingold Heppner, Barbara, Kim, S. Rim, Kos, Zuzana, Kreipe, Hans H., Lakhani, Sunil R., Penault-Llorca, Frederique, Pruneri, Giancarlo, Radosevic-Robin, Nina, Rimm, David L., Schnitt, Stuart J., Sinn, Bruno V., Sinn, Peter., Sirtaine, Nicolas, O'Toole, Sandra A., Viale, Giuseppe, Van De Vijver, Koen, De Wind, Roland, Von Minckwitz, Gunter, Klauschen, Frederick, Untch, Michael, Fasching, Peter A., Reimer, Toralf, Willard-Gallo, Karen, Michiels, Stefan, Loi, Sherene and Salgado, Roberto (2016) Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group. Modern Pathology, 29 10: 1155-1164. doi:10.1038/modpathol.2016.109

  • Smid, Marcel, Rodriguez-Gonzalez, F. German, Sieuwerts, Anieta M., Salgado, Roberto, Prager-Van Der Smissen, Wendy J. C., van der Vlugt-Daane, Michelle, Van Galen, Anne, Nik-Zainal, Serena, Staaf, Johan, Brinkman, Arie B., Van De Vijver, Marc J., Richardson, Andrea L., Fatima, Aquila, Berentsen, Kim, Butler, Adam, Martin, Sancha, Davies, Helen R., Debets, Reno, Meijer-Van Gelder, Marion E., Van Deurzen, Carolien H. M., Macgrogan, Gaeetan, Van Den Eynden, Gert G. G. M., Purdie, Colin, Thompson, Alastair M., Caldas, Carlos, Span, Paul N., Simpson, Peter T., Lakhani, Sunil R., Van Laere, Steven, Desmedt, Christine, Ringner, Markus, Tommasi, Stefania, Eyford, Jorunn, Broeks, Annegien, Vincent-Salomon, Anne, Futreal, P. Andrew, Knappskog, Stian, King, Tari, Thomas, Gilles, Viari, Alain, Langerod, Anita, Borresen-Dale, Anne-Lise, Birney, Ewan, Stunnenberg, Hendrik G., Stratton, Mike, Foekens, John A. and Martens, John W. M. (2016) Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration. Nature Communications, 7 12910.1-12910.9. doi:10.1038/ncomms12910

  • Burgess, Joshua T., Bolderson, Emma, Saunus, Jodi M., Zhang, Shu-Dong, Reid, Lynne E., McNicol, Anne Marie, Lakhani, Sunil R., Cuff, Katharine, Richard, Kerry, Richard, Derek J. and O'Byrne, Kenneth J. (2016) SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer. Oncotarget, 7 45: 72807-72818. doi:10.18632/oncotarget.12020

  • Milevskiy, Michael J. G., Al-Ejeh, Fares, Saunus, Jodi M., Northwood, Korinne S., Bailey, Peter J., Betts, Joshua A., McCart Reed, Amy E., Nephew, Kenneth P., Stone, Andrew, Gee, Julia M. W., Dowhan, Dennis H., Dray, Eloise, Shewan, Annette M., French, Juliet D., Edwards, Stacey L., Clark, Susan J., Lakhani, Sunil R. and Brown, Melissa A. (2016) Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer. Human Molecular Genetics, 25 15: 3269-3283. doi:10.1093/hmg/ddw177

  • Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Young Seok, Smid, Marcel, Brinkman, Arie B., Morganella, Sandro, Aure, Miriam R., Lingjaerde, Ole Christian, Langerod, Anita, Ringner, Markus, Ahn, Sung-Min, Boyault, Sandrine, Brock, Jane E., Broeks, Annegien, Butler, Adam, Desmedt, Christine, Dirix, Luc, Dronov, Serge, Fatima, Aquila, Foekens, John A., Gerstung, Moritz, Hooijer, Gerrit K. J., Jang, Se Jin, Jones, David R., Kim, Hyung-Yong, King, Tari A., Krishnamurthy, Savitri, Lee, Hee Jin, Lee, Jeong-Yeon, Li, Yilong, McLaren, Stuart, Menzies, Andrew, Mustonen, Ville, O'Meara, Sarah, Pauporte, Iris, Pivot, Xavier, Purdie, Colin A., Raine, Keiran, Ramakrishnan, Kamna, Rodriguez-Gonzalez, F. German, Romieu, Gilles, Sieuwerts, Anieta M., Simpson, Peter T., Shepherd, Rebecca, Stebbings, Lucy, Stefansson, Olafur A., Teague, Jon, Tommasi, Stefania, Treilleux, Isabelle, Van den Eynden, Gert G., Vermeulen, Peter, Vincent-Salomon, Anne, Yates, Lucy, Caldas, Carlos, van't Veer, Laura, Tutt, Andrew, Knappskog, Stian, Tan, Benita Kiat Tee, Jonkers, Jos, Borg, Ake, Ueno, Naoto T., Sotiriou, Christos, Viari, Alain, Futreal, P. Andrew, Campbell, Peter J., Span, Paul N., Van Laere, Steven, Lakhani, Sunil R., Eyfjord, Jorunn E., Thompson, Alastair M., Birney, Ewan, Stunnenberg, Hendrik G., van de Vijver, Marc J., Martens, John W. M., Borresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles and Stratton, Michael R. (2016) Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature, 534 7605: 47-+. doi:10.1038/nature17676

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  • Waddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010) Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 3: 661-677. doi:10.1007/s10549-009-0653-1

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  • Grigoriadis, Anita, Caballero, Otavia L., Hoek, Keith S., da Silva, Leonard, Chen, Yao-Tseng, Shin, Sandra J., Jungbluth, Achim A., Miller, Lance D., Clouston, David, Cebon, Jonathan, Old, Lloyd J., Lakhani, Sunil R., Simpson, Andrew J.G. and Neville, A. Munro Neville (2009) CT-X antigen expression in human breast cancer. Proceedings of the National Academy of Sciences, 106 32: 13493-13498. doi:10.1073/pnas.0906840106

  • Gilbert, Fiona J., Warren, Ruth M. L., Kwan-Lim, Gek, Thompson, Deborah J., Eeles, Ros A., Evans, D. Gareth, Leach, Martin O., United Kingdom Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group and Lakhani, S. R. (2009) Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features. Radiology, 252 2: 358-368. doi:10.1148/radiol.2522081032

  • Cummings, Margaret C., Da Silva, Leonard, Papadimos, David J. and Lakhani, Sunil R. (2009) Fibroadenoma and intraduct papilloma--a common pathogenesis?. Virchows Archiv, 455 3: 271-275. doi:10.1007/s00428-009-0817-8

  • Shin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009) Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 4: 496-504. doi:10.1097/PAS.0b013e31818af361

  • Vargas, Ana-Cristina, Lakhani‌, Sunil R. and Simpson, Peter T. (2009) Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 2: 233-243. doi:10.2217/14796694.5.2.233

  • Pakkiri, P, Lakhani, SR and Smart, CE (2009) Current and future approach to the pathologist's assessment for targeted therapy in breast cancer. Pathology, 41 1: 89-99. doi:10.1080/00313020802563551

  • Da Silva, Leonard, Buck, Lyndall, Simpson, Peter T., Reid, Lynne, McCallum, Naomi, Madigan, Barry J. and Lakhani, Sunil R. (2009) Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archiv, 454 1: 107-114. doi:10.1007/s00428-008-0700-z

  • Smart, Chanel E., Clarke, Catherine, Brooks, Kelly M., Raghavendra, Ashwini, Brewster, Brooke L., French, Juliet D., Hetherington, Rehan, Fleming, Jean S., Rothnagel, Joseph A., Wainwright, Brandon, Lakhani, Sunil R. and Brown, Melissa A. (2008) Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Breast Cancer Research and Treatment, 112 2: 237-241. doi:10.1007/s10549-007-9859-2

  • Reis-Filho, J.S. and Lakhani, S.R. (2008) Breast cancer special types: why bother?. Journal of Pathology, 216 4: 394-398. doi:10.1002/path.2419

  • Morrison, Brian J., Schmidt, Chis W., Lakhani, Sunil, Reynolds, Brent A. and Alejandro, Lopez J. (2008) Breast cancer stem cells: Implications for therapy of breast cancer. Breast Cancer Research, 10 4: 210-1-210-14. doi:10.1186/bcr2111

  • Simpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008) Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 3: 231-244. doi:10.1002/path.2358

  • DA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008) Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 5: 773-783. doi:10.1097/PAS.0b013e318158d6c5

  • Spurdle, A.B., Lakhani, S.R., Healey, S., Parry, S., Da Silva, L. M., Brinkworth, R.I., Hopper, J.L., Brown, M.A., Babikyan, D., Chenevix-Trench, G., Tavtigian, S.V. and Goldgar, D.E. (2008) Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators. Journal of Clinical Oncology, 26 10: 1657-1663. doi:10.1200/JCO.2007.13.2779

  • Mortimer, R. and Lakhani, S. (2008) Pathology in education and practice: a time for integration?. Australian Health Review, 32 2: 319-321.

  • Wayte, Nicola, Da Silva, Leonard, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2008) What's in a cancer syndrome? Genes, phenotype and pathology. Pathology, 40 3: 247-259. doi:10.1080/00313020801911553

  • Lovelock, Paul K., Spurdle, Amanda B., Mok, Myth T. S., Farrugia, Daniel J., Lakhani, Sunil R., Healey, Sue, Arnold, Stephen, Buchanan, Daniel, kConFab Investigators, Couch, Fergus J., Henderson, Berik R., Goldgar, David E., Tavtigian, Sean V., Chenevix-Trench, Georgia and Brown, Melissa A (2007) Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?. Breast Cancer Research, 9 6: R82: 1-13. doi:10.1186/bcr1826

  • Marsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007) Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 3: 377-389. doi:10.1007/s10549-006-9461-z

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  • Da Silva, L., Clarke, C. and Lakhani, S.R. (2007) Demystifying basal-like breast carcinomas. Journal of Clinical Pathology, 60 12: 1328-1332. doi:10.1136/jcp.2006.041731

  • Fulford, L. G., Reis, J. S., Mackay, A., Fenwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, H. W. and Lakhani, S. R. (2007) Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi. Laboratory Investigation, 87 Supplement 1s: 305A-306A. doi:10.1038/sj.labinvest.3700582

  • Fulford, Laura G., Reis-Filho, Jorge S., Ryder, Ken, Jones, Chris, Gillett, Cheryl E., Hanby, Andrew, Easton, Douglas and Lakhani, Sunil R. (2007) Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Research, 9 1: 1-11. doi:10.1186/bcr1636

  • Fulford, L. G., Reis, J. S., Mackay, A., Feinwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, R. H. W. and Lakhani, Sunil R. (2007) Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis. Modern Pathology, 20 Supplement 2s: 305A-306A. doi:10.1038/sj.modpathol.3800815

  • Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007) In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 5: 409-411. doi:10.1016/j.ccr.2007.10.026

  • Reis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006) FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 22: 6652-6662. doi:10.1158/1078-0432.CCR-06-1164

  • Chenevix-Trench, Georgia, Healey, Sue, Lakhani, Sunil, Waring, Paul, Cummings, Margaret, Brinkworth, Ross, Deffenbaugh, Amie M., Burbidge, Lynn Anne, Pruss, Dmitry, Judkins, Thad, Scholl, Tom, Bekessy, Anna, Marsh, Anna, Lovelock, Paul, Wong, Ming, Tesoriero, Andrea, Renard, Helene, Southey, Melissa, Hopper, John L., Yannoukakos, Koulis, Brown, Melissa, kConFab Investigators, Easton, Douglas, Tavtigian, Sean V., Goldgar, David and Spurdle, Amanda B. (2006) Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variance of Unknown Clinical Significance. Cancer Research, 66 4: 2019-2027. doi:10.1158/0008-5472.CAN-05-3546

  • Warren, Ruth, Hayes, Carmel, Pointon, Linda, Hoff, Rebecca, Gilbert, Fiona J., Padhani, Anwar R., Rubin, Caroline, Kaplan, Glenda, Raza, Kauza, Wilkinson, Laura, Hall-Craggs, Margaret, Kessar, Preminda, Rankin, Sheila, Dixon, Adrian K., Walsh, James, Turnbull, Lindsay, Britton, Peter, Sinnatamby, Ruchi, Easton, Doug, Thompson, Deborah, Lakhani, Sunil R., Leach, Martin O. and MARIBS (2006) A Test of Performance of Breast MRI Interpretation in a Multicentre Screening Study. Magnetic Resonance Imaging, 24 7: 917-929. doi:10.1016/j.mri.2006.03.004

  • Banerjee, S., Reis, J. S., Ashley, S., Steele, D., Ashworth, A., Lakhani, S. R. and Smith, I. E. (2006) Basal-like breast carcinomas: clinical outcome and response to chemotherapy. Journal of Clinical Pathology, 59 7: 729-735. doi:10.1136/jcp.2005.033043

  • Griebsch, I., Brown, J., Boggis, C., Dixon, A., Dixon, M., Easton, D., Eeles, R., Evans, D. G., Gilbert, F. J., Hawnaur, J., Kessar, P., Lakhani, S. R., Moss, S. M., Nerurkar, A. and Padhani, A. R. (2006) Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer. British Journal of Cancer, 95 7: 801-810. doi:10.1038/sj.bjc.6603356

  • Reis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R. and Schmitt, F. C. (2006) EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology, 209 4: 445-453. doi:10.1002/path.2004

  • Lakhani, S. R. (2006) EGFR expression predicts BRCA1 status in patients with breast cancer - In response. Clinical Cancer Research, 12 2: 671-671. doi:10.1158/1078-0432.CCR-05-2297

  • Warren, RML, Thompson, D, Pointon, LJ, Hoff, R, Gilbert, FJ, Padhani, AR, Easton, DF, Lakhani, SR and Leach, MO (2006) Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study. Radiology, 239 3: 677-685. doi:10.1148/radiol.2393042007

  • Lakhani, S. and Bissell, M. (2006) Introduction: The role of myoepithelial cells in integration of form and function in the mammary gland. Journal of Mammary Gland Biology & Neoplasia, 10 3: 197-198. doi:10.1007/s10911-005-9580-x

  • Clarke, C. L., Sandle, J., Jones, A. A., Sofronis, A., Patani, N. R. and Lakhani, S. R. (2006) Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers. British Journal of Cancer, 95 4: 515-519. doi:10.1038/sj.bjc.6603298

  • Reis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R. and Schmitt, F. C. (2006) Metaplastic breast carcinomas are basal-like tumours. Histopathology, 49 1: 10-21. doi:10.1111/j.1365-2559.2006.02467.x

  • Jones, R. L., Lakhani, S. R., Ring, A. E., Ashley, S., Walsh, G. and Smith, I. E. (2006) Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma. British Journal of Cancer, 94 3: 358-362. doi:10.1038/sj.bjc.6602950

  • Lakhani, Sunil R. (2006) Reply to the letter to the editor by Van Diest, et al. Clinical Cancer Research, 12 2: 671-671. doi:10.1158/1078-0432.CCR-05-2297

  • Fulford, L. G., Easton, D. F., Reis-Filho, J. S., Sofronis, A., Gillett, C. E., Lakhani, S. R. and Hanby, A. (2006) Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology, 49 1: 22-34. doi:10.1111/j.1365-2559.2006.02453.x

  • Lakhani, SR, Audretsch, W, Cleton-Jensen, AM, Cutuli, B, Ellis, I, Eusebi, V, Greco, M, Houslton, RS, Kuhl, CK, Kurtz, J, Palacios, J, Peterse, H, Rochard, F and Rutgers, E (2006) The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?. European Journal of Cancer, 42 14: 2205-2211. doi:10.1016/j.ejca.2006.03.019

  • Reis-Filho, Jorge S., Simpson, Peter T., Gale, Theodora and Lakhani, Sunil R. (2005) The molecular genetics of breast cancer: The contribution of comparative genomic hybridization. Pathology Research & Practice, 201 11: 713-725. doi:10.1016/j.prp.2005.05.013

  • Clarke, Catherine, Sandle, Jennifer and Lakhani, Sunil R. (2005) Myoepithelial calls: Pathology, cell separation and markers of myoepithelial differentiation. Journal of Mammary Gland Biology and Neoplasia, 10 3: 273-280. doi:10.1007/s10911-005-9587-3

  • Stephens, P., Edkins, S., Davies, H., Greenman, C., Cox, C., Hunter, C., Bignell, G., Teague, J., Smith, R., Stevens, C., O'Meara, S., Parker, A., Tarpey, P., Avis, T., Barthorpe, A., Brackenbury, L., Buck, G., Butler, A., Clements, J., Cole, J., Dicks, E., Edwards, K., Forbes, S., Gorton, M., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J., Jones, D., Kosmidou, V., Laman, R., Lugg, R., Menzies, A., Perry, J., Petty, R., Raine, K., Shepherd, R., Small, A., Solomon, H., Stephens, Y., Tofts, C., Varian, J., Webb, A., West, S., Widaa, S., Yates, A., Brasseur, F., Cooper, C.S., Flanagan, A.M., Green, A., Knowles, M., Leung, S.Y., Looijenga, L.H.J., Malkowicz, B., Pierotti, M. A., Teh, B., Yuen, S.T., Nicholson, A.G., Lakhani, S., Easton, D.F., Weber, B.L., Stratton, M.R., Futreal, P.A. and Wooster, R. (2005) A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nature Genetics, 37 6: 590-592. doi:10.1038/ng1571

  • Simpson, P. T., Gale, T., Reis-Filho, J. S., Jones, C., Parry, S., Sloane, J. P., Hanby, A., Pinder, S. E., Lee, A. H. S., Humphreys, S., Ellis, I. O. and Lakhani, S. R. (2005) Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. American Journal of Surgical Pathology, 29 6: 734-746. doi:10.1097/01.pas.0000157295.93914.3b

  • Banerji, Udai, O'Donnell, Anne, Scurr, Michelle, Pacey, Simon, Stapleton, Sarah, Asad, Yasmin, Simmons, Laura, Maloney, Alison, Raynaud, Florence, Campbell, Maeli, Walton, Micheal, Lakhani, Sunil, Kaye, Stanley, Workman, Paul and Judson, Ian (2005) Phase I pharmacokinetic and pharmacodynarnic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies. Journal of Clinical Oncology, 23 18: 4152-4161. doi:10.1200/JCO.2005.00.612

  • Gui, GPH, Joubert, DJ, Reichert, R, Ward, A, Lakhani, S, Osin, P, Nerurkar, A, A'Hern, R, Benson, K and Underwood, SR (2005) Continued axillary sampling is unnecessary and provides no further information to sentinel node biopsy in staging breast cancer. Ejso, 31 7: 707-714. doi:10.1016/j.ejso.2005.04.014

  • Reis-Filho, Jorge S., Milanezi, Fernanda, Carvalho, Silvia, Simpson, Peter T., Steele, Dawn, Savage, Kay, Lambros, Maryou B. K., Pereira, Emilio M., Nesland, John M., Lakhani, Sunil R. and Schmitt, Fernando C. (2005) Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Research, 7 6: R1028-R1035. doi:10.1186/bcr1341

  • Simpson, P. T., Reis-Filho, J. S., Gale, T. and Lakhani, S. R. (2005) Molecular evolution of breast cancer. Journal of Pathology, 205 2: 248-254. doi:10.1002/path.1691

  • Reis-Filho, J. S., Simpson, P. T., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Valgeirrson, H., Lambros, M., Ashworth, A., Palacios, J., Schmitt, F. and Lakhani, S. R. (2005) Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity. Journal of Pathology, 207 1: 1-13. doi:10.1002/path.1806

  • Lakhani, S. R., Reis-Filho, J. S., Fulford, L., Penault-Llorca, F., van der Vjiver, M., Parry, S., Bishop, T., Benitez, J., Rivas, C., Bignon, Y. J., Chang-Claude, J., Hamann, U., Cornelisse, C. J., Devilee, P. and Beckmann, M. W. (2005) Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clinical Cancer Research, 11 14: 5175-5180. doi:10.1158/1078-0432.CCR-04-2424

  • Warren, RML, Pointon, L, Thompson, D, Hoff, R, Gilbert, FJ, Padhani, A, Easton, D, Lakhani, SR and Leach, MO (2005) Reading protocol for dynamic contrast-enhanced MR images of the breast: Sensitivity and specificity analysis. Radiology, 236 3: 779-788. doi:10.1148/radiol.2363040735

  • Leach, M. O., Boggis, C. R. M., Dixon, A. K., Easton, D. F., Eeles, R. A., Evans, D. G. R., Gilbert, F. J., Griebsch, I., Hoff, R. J. C., Kessar, P., Lakhani, S. R. and Moss, S. M. (2005) Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS). The Lancet, 365 9473: 1769-1778. doi:10.1016/S0140-6736(05)66481-1

  • Davies, H, Hunter, C, Smith, R, Stephens, P, Greenman, C, Bignell, G, Teague, B, Butler, A, Edkins, S, Stevens, C, Parker, A, O'Meara, S, Avis, T, Barthorpe, S, Brackenbury, L, Buck, G, Clements, B, Cole, J, Dicks, E, Edwards, K, Forbes, S, Gorton, M, Gray, K, Halliday, K, Harrison, R, Hills, K, Hinton, J, Jones, D, Kosmidou, V, Laman, R, Lugg, R, Menzies, A, Perry, J, Petty, R, Raine, K, Shepherd, R, Small, A, Solomon, H, Stephens, Y, Tofts, C, Varian, J, Webb, A, West, S, Widaa, S, Yates, A, Brasseur, F, Cooper, CS, Flanagan, AM, Green, A, Knowles, M, Leung, SY, Looijenga, LHJ, Malkowicz, B, Pierotti, MA, Teh, BT, Yuen, ST, Lakhani, SR, Easton, DF, Weber, BL, Goldstraw, P, Nicholson, AG, Wooster, R, Stratton, MR and Futreal, PA (2005) Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Research, 65 17: 7591-7595. doi:10.1158/0008-5472.CAN-05-1855

  • Jacquemier, J., Padovani, L., Rabayrol, L., Lakhani, S. R., Penault-Llorca, F., Denoux, Y., Fiche, M., Figueiro, P., Maisongrosse, V., Ledoussal, V., Penuela, J. M., Udvarhely, N., El Makdissi, G., Ginestier, C. and Geneix, J. (2005) Typical medullary breast carcinomas have a basal/myoepithelial phenotype. Journal of Pathology, 207 3: 260-268. doi:10.1002/path.1845

  • Jones, Chris, Ford, Emily, Gillett, Cheryl, Ryder, Ken, Merrett, Samantha, Reis, Jorge S., Fulford, Laura G., Hanby, Andrew and Lakhani, Sunil R. (2004) Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. Clinical Cancer Research, 10 18: 5988-5997. doi:10.1158/1078-0432.CCR-03-0731

  • Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Cossu, Antonio, Reis-Filho, Jorge S., Fulford, Laura, Dexter, Tim, Davies, Susan, Bulmer, Karen, Ford, Emily, Parry, Suzanne, Budroni, Mario, Palmieri, Giuseppe, Neville, A. Munro, O'Hare, Michael J. and Lakhani, Sunil R. (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. Cancer Research, 64 9: 3037-3045. doi:10.1158/0008-5472.CAN-03-2028

  • Lakhani, Sunil R. (2004) Putting the brakes on cylindromatosis?. New England Journal of Medicine, 350 2: 187-188. doi:10.1056/NEJMcibr032650

  • Reis-Filho, J. S., Fulford, L. G., Crebassa, B., Carpentier, S. and Lakhani, S. R. (2004) Collagenous spherulosis in an adenomyoepithelioma of the breast. Journal of Clinical Pathology, 57 1: 83-86. doi:10.1136/jcp.57.1.83

  • Clarke, CL, Sandle, J, Parry, SC, Reis, JS, O'Hare, MJ and Lakhani, SR (2004) Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. Journal of Pathology, 204 2: 147-152. doi:10.1002/path.1647

  • Simpson, Peter T., Gale, Theodora, Reis-Filho, Jorge S, Jones, Chris, Parry, Suzanne, Steele, Dawn, Cossu, Antonio, Budroni, Mario, Palmieri, Giuseppe and Lakhani, Sunil R (2004) Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue. Journal of Pathology, 202 3: 274-285. doi:10.1002/path.1530

  • Angele, S., Jones, C., Reis Filho, J. S., Fulford, L. G., Treilleux, I. and Lakhani, S. R. (2004) Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast. Journal of Clinical Pathology, 57 11: 1179-1184. doi:10.1136/jcp.2004.017434

  • Millis, R. R., Pinder, S. E., Ryder, K., Howitt, R. and Lakhani, S. R. (2004) Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast. British Journal of Cancer, 90 8: 1538-1542. doi:10.1038/sj.bjc.6601704

  • Ring, A. E., Smith, I. E., Ashley, S., Fulford, L. G. and Lakhani, S. R. (2004) Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. British Journal of Cancer, 91 12: 2012-2017. doi:10.1038/sj.bjc.6602235

  • Lakhani, SR, Manek, S, Penault-Llorca, F, Flanagan, A, Arnout, L, Merrett, S, McGuffog, L, Steele, D, Devilee, P, Klijn, JGM, Meijers-Heijboer, H, Radice, P, Pilotti, S, Nevanlinna, H, Butzow, R, Sobol, H, Jacquemier, J, Lyonet, DS, Neuhausen, SL, Weber, B, Wagner, T, Winqvist, R, Bignon, YJ, Monti, F, Schmitt, F, Lenoir, G, Seitz, S, Hamman, U, Pharoah, P, Lane, G, Ponder, B, Bishop, DT and Easton, DF (2004) Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clinical Cancer Research, 10 7: 2473-2481. doi:10.1158/1078-0432.CCR-1029-3

  • Lakhani, Sunil R. (2004) The diagnosis and management of pre-invasive breast disease: Editor's reply. Breast Cancer Research, 6 1: E4: 1-2. doi:10.1186/bcr741

  • Gui, GPH, Behranwala, KA, Abdullah, N, Seet, J, Osin, P, Nerurkar, A and Lakhani, SR (2004) The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction. British Journal of Plastic Surgery, 57 2: 146-149. doi:10.1016/j.bjps.2003.11.030

  • Reis-Filho, Jorge S., Fulford, Laura G., Freeman, Alex and Lakhani, Sunil R. (2003) Pathologic quiz case: A 93-year-old woman with an enlarged and tender left breast. Archives of Pathology & Laboratory Medicine, 127 12: 1626-1628.

  • Lakhani, Sunil R. (2003) The diagnosis and management of pre-invasive breast disease: Editor's reply. Breast Cancer Research, 6 1: E4.1-E4.2. doi:10.1186/bcr741

  • Reis-Filho, Jorge S., Fulford, Laura G., Lakhani, Sunil R. and Schmitt, Fernando C. (2003) A 62-year-old woman with a 4.5-cm nodule in the right breast. Archives of Pathology and Laboratory Medicine, 127 9: e396-e398.

  • Lakhani, Sunil R. (2003) The morphology of breast tumors in BRCA1/2 carriers. Pathology Case Reviews, 8 5: 240-244.

  • Jones, Chris, Tooze, Reuben and Lakhani, Sunil R. (2003) Malignant adenomyoepithelioma of the breast metastasizing to the liver [Letter to the Editor]. Virchows Archiv, 442 5: 504-506. doi:10.1007/s00428-003-0806-2

  • Timpanidis, Penelope C., Lakhani, Sunil R. and Groves, Richard W. (2003) Progesterone receptor-positive eruptive syringoma associated with diabetes. Journal of The American Academy of Dermatology, 48 5, Supp. 1: S103-S104. doi:10.1067/mjd.2003.159

  • Logarajah, S, Hunter, P, Kraman, M, Steele, D, Lakhani, S, Bobrow, L, Venkitaraman, A and Wagner, S (2003) BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. Oncogene, 22 36: 5572-5578. doi:10.1038/sj.onc.1206689

  • Warren, R and Lakhani, SR (2003) Can the stroma provide the clue to the cellular basis for mammographic density?. Breast Cancer Research, 5 5: 225-227. doi:10.1186/bcr642

  • Jones, C, Merrett, S, Thomas, VA, Barker, TH and Lakhani, SR (2003) Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast. Journal of Pathology, 199 2: 152-156. doi:10.1002/path.1280

  • Reis-Filho, Jorge S. and Lakhani, Sunil R. (2003) Genetic alterations in pre-invasive lesions. Breast Cancer Research, 5 6: 313-319. doi:10.1186/bcr650

  • Lakhani, Sunil R. (2003) In-situ lobular neoplasia: time for an awakening. The Lancet, 361 9352: 96-96. doi:10.1016/S0140-6736(03)12240-4

  • Simpson, Peter T., Gale, Theodora, Fulford, Laura G., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2003) Pathology of atypical lobular hyperplasia and lobular carcinoma in situ. Breast Cancer Research, 5 5: 258-262. doi:10.1186/bcr624

  • Pia-Foschini, M., Reis, J. S., Eusebi, V. and Lakhani, S. R. (2003) Salivary gland-like tumours of the breast: surgical and molecular pathology. Journal of Clinical Pathology, 56 7: 497-506. doi:10.1136/jcp.56.7.497

  • Lakhani, Sunil R. (2003) The diagnosis and management of pre-invasive breast disease — current challenges, future hopes. Breast Cancer Research, 5 5: 248-249. doi:10.1186/bcr641

  • Novelli, M, Cossu, A, Oukrif, D, Quaglia, A, Lakhani, S, Poulsom, R, Sasieni, P, Carta, P, Contini, M, Pasca, A, Palmieri, G, Bodmer, W, Tanda, F and Wright, N (2003) X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proceedings of The National Academy of Sciences of The United States of America, 100 6: 3311-3314. doi:10.1073/pnas.0437825100

  • Mackay, A., Jones, C., Dexter, T., Silva, R. L. A., Bulmer, K., Jones, A., Simpson, P., Harris, R. A., Jat, P. S., Neville, A. M., Reis, L. F. L., Lakhani, S. R. and O'Hare, M. J. (2003) cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells. Oncogene, 22 17: 2680-2688. doi:10.1038/sj.onc.1206349

  • Lakhani, Sunil R., van de Vijver, Marc J., Jacquemier, Jocelyne, Anderson, Thomas J., Osin, Peter P., McGuffog, Lesley and Easton, Douglas F. (2002) The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. Journal of Clinical Oncology, 20 9: 2310-2318. doi:10.1200/JCO.2002.09.023

  • Clarke, C. and Lakhani, S. R. (2002) The Significance of Early Breast Lesions. Breast Cancer Online, 5 1-5.

  • Sawyer, EJ, Hanby, AM, Rowan, AJ, Gillett, CE, Thomas, RE, Poulsom, R, Lakhani, SR, Ellis, IO, Ellis, P and Tomlinson, IPM (2002) The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours. Journal of Pathology, 196 4: 437-444. doi:10.1002/path.1067

  • Suzuki, RN, Entwistle, A, Atherton, AJ, Clarke, C, Lakhani, SR and O'Hare, MJ (2002) The expression patterns of integrin subunits on human breast tissues obtained during pregnancy. Cell Biology International, 26 7: 593-598. doi:10.1006/cbir.2002.0880

  • Lakhani, Sunil R. and Ashworth, Alan (2001) Microarray and histopathological analysis of tumours: The future and the past?. Nature Reviews Cancer, 1 2: 151-157. doi:10.1038/35101087

  • Jones, C., Nonni, A. V., Fulford, L., Merrett, S., Chaggar, R., Eusebi, V. and Lakhani, S. R. (2001) CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. British Journal of Cancer, 85 3: 422-427. doi:10.1054/bjoc.2001.1869

  • Lakhani, Sunil R., O'Hare, Michael J. and Ashworth, Alan (2001) Profiling familial breast cancer. Nature Medicine, 7 4: 408-410. doi:10.1038/86464

  • Lakhani, SR, O'Hare, MJ and Ashworth, A (2001) Profiling familial breast cancer. Nature Medicine, 7 4: 408-410. doi:10.1038/86464

  • Stone, JG, Coleman, G, Gusterson, B, Marossy, A, Lakhani, SR, Ward, A, Nash, A, McKinna, A, A'Hern, R, Stratton, MR and Houlston, RS (2001) Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. Cancer Letters, 167 2: 171-174. doi:10.1016/S0304-3835(01)00448-7

  • Leonard, N, Chaggar, R, Jones, C, Takahashi, M, Nikitopoulou, A and Lakhani, SR (2001) Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours. Journal of Clinical Pathology, 54 9: 689-692.

  • Ralleigh, G, Walker, AE, Hall-Craggs, MA, Lakhani, SR and Saunders, C (2001) MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change. European Radiology, 11 9: 1651-1658. doi:10.1007/s003300100837

  • Jones, C, Damiani, S, Wells, D, Chaggar, R, Lakhani, SR and Eusebi, V (2001) Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast. American Journal of Pathology, 158 1: 207-214. doi:10.1016/S0002-9440(10)63959-4

  • Lakhani, SR (2001) Molecular genetics of solid tumours: translating research into clinical practice. What we could do now: breast cancer. Journal of Clinical Pathology-molecular Pathology, 54 5: 281-284.

  • Lakhani, SR and O'Hare, MJ (2001) The mammary myoepithelial cell - Cinderella or ugly sister?. Breast Cancer Research, 3 1: 1-4. doi:10.1186/bcr260

  • Suzuki, R., Atherton, A. J., O'Hare, M. J., Entwistle, A., Lakhani, S. R. and Clarke, C. (2000) Proliferation and differentiation in the human breast during pregnancy. Differentiation, 66 2-3: 106-115. doi:10.1046/j.1432-0436.2000.660205.x

  • Peng, Huaizheng, Lakhani, Sunil R., Lee, Chungyin, Zheng, Qiang, Chaggar, Ranbir K., Wright, Nicholas A., Pan, Langxing and Isaacson, Peter G. (2000) Clonality analysis of defined cell populations in paraffin-embedded tissue sections by RT-PCR amplification of X-linked G6PD gene. Journal of Pathology, 191 3: 313-317. doi:10.1002/1096-9896(2000)9999:9999<::AID-PATH621>3.0.CO;2-3

  • Jones, C., Foschini, M. P., Chaggar, R., Lu, Y. J., Wells, D., Shipley, J. M., Eusebi, V. and Lakhani, S. R. (2000) Comparative genomic hybridization analysis of myoepithelial carcinoma of the breast. Laboratory Investigation, 80 6: 831-836.

  • Bignell, Graham R., Warren, William, Seal, Sheila, Takahashi, Meiko, Rapley, Elizabeth, Barfoot, Rita, Green, Helen, Brown, Carolanne, Biggs, Patrick J., Lakhani, Sunil R., Jones, Christopher, Hansen, Juliana, Blair, Edward, Hofmann, Benedikt, Siebert, Reiner, Turner, Gwen, Evans, D. Gareth, Schrander-Stumpel, Connie, Beemer, Frits A., van den Ouweland, Ans, Halley, Dicky, Delpech, Bertrand, Cleveland, Mark G., Jaakko, Irene Leigh, Rasmussen, Leisti Sonja, Wallace, Margaret R., Fenske, Christiane, Banerjee, Piu, Oiso, Naoki, Chaggar, Ranbir, Merrett, Samantha, Leonard, Niamh, Huber, Marcel, Hohl, Daniel, Chapman, Pam, Burn, John, Swift, Sally, Smith, Anna, Ashworth, Alan and Stratton, Michael R. (2000) Identification of the familial cylindromatosis tumour-suppressor gene. Nature Genetics, 25 2: 160-165. doi:10.1038/76006

  • Bigio, Irving J., Bown, Stephen G., Briggs, Gavin, Kelley, Christine, Lakhani, Suni, Pickard, David, Ripley, Paul M., Rose, Ian G. and Saunders, Christobel (2000) Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results. Journal of Biomedical Optics, 5 2: 221-228. doi:10.1117/1.429990

  • Masters, John R. W. and Lakhani, Sunil R. (2000) How diagnosis with microarrays can help cancer patients. Nature, 404 6781: 921-921. doi:10.1038/35010139

  • Waddington, W. A., Taylor, I., Lakhani, S. R., Short, M. D. and Ell, P. J. (2000) Radiation safety of the sentinel lymph node technique in breast cancer. European Journal of Nuclear Medicine, 27 4: 277-291.

  • Jones, Chris, Payne, Joachim, Wells, Dagan, Delhanty, Joy D. A., Lakhani, Sunil R. and Kortenkamp, Andreas (2000) Comparative genomic hybridization reveals extensive variation among different MCF-7 cell stocks. Cancer Genetics and Cytogenetics, 117 2: 153-158. doi:10.1016/S0165-4608(99)00158-2

  • Payne, J., Jones, C., Lakhani, S. and Kortenkamp, A. (2000) Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens. Science of the Total Environment, 248 1: 51-62. doi:10.1016/S0048-9697(99)00479-9

  • Sawyer, Elinor J., Hanby, Andrew M., Ellis, Paul, Lakhani, Sunil R., Ellis, Ian O., Boyle, Sue and Tomlinson, Ian P. M. (2000) Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components. American Journal of Pathology, 156 3: 1093-1098. doi:10.1016/S0002-9440(10)64977-2

  • Lakhani, Sunil R., Gusterson, Barry A., Jacquemier, Jocelyne, Sloane, John P., Anderson, Thomas J., van de Vijver, Marc J., Venter, Deon, Freeman, Alex, Antoniou, Antonios, McGuffog, Lesley, Smyth, Elizabeth, Steel, C. Michael, Haites, Nava, Scott, Rodney J., Goldgar, David, Neuhausen, Susan, Daly, Peter A., Ormiston, Wilma, McManus, Ross, Scherneck, Siegfried, Ponder, Bruce A. J., Futreal, P. Andrew, Peto, Julian, Stoppa-Lyonnet, Dominique, Bignon, Yves-Jean, Struewing, Jeffery P., Bishop, D. Timothy, Klijn, J.G.M., Devilee, Peter, Cornelisse, Cees J., Lasset, Christine, Lenoir, Gilbert, Barkardottir, Rosa Bjork, Egilsson, Valgardur, Hamann, Ute, Chang-Claude, Jenny, Sobol, Hagay, Weber, Barbara, Easton, Douglas F. and Stratton, Michael R. (2000) The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2. Clinical Cancer Research, 6 3: 782-789.

  • Rahman, N., Stone, J. G., Coleman, G., Gusterson, B., Seal, S., Lakhani, S. R., Ward, A., Nash, A., McKinna, A., A'Hern, R. and Houlston, R. S. (2000) Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene. British Journal of Cancer, 82 3: 568-570. doi:10.1054/bjoc.1999.0965

  • Takahashi, M., Rapley, E., Biggs, P. J., Lakhani, S. R., Cooke, D., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Schrander-Stumpel, C., Beemer, F. A., van Vloten, W. A., Breuning, M. H., van den Ouweland, A., Halley, D., Delpech, B., Cleveland, M., Leigh, I., Chapman, P., Burn, J., Hohl, D., Gorog, J. P., Seal, S., Mangion, J., Warren, W., Bignell, G. and Stratton, M. R. (2000) Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13. Human Genetics, 106 1: 58-65. doi:10.1007/s004399900227

  • Lakhani, Sunil R., Chaggar, Ranbir, Davies, Susan, Jones, Chris, Collins, Nadine, Odel, Christopher, Stratton, Michael R. and O'Hare, Michael J. (1999) Genetic alterations in 'normal' luminal and myoepithelial cells of the breast. Journal of Pathology, 189 4: 496-503. doi:10.1002/(SICI)1096-9896(199912)189:4<496::AID-PATH485>3.3.CO;2-4

  • Colville, C. C., Krysa, J., Saunders, C., Schneidau, A. and Lakhani, S. R. (1999) re: Fibroadenoma with keratinous squamous cysts. Breast, 8 6: 347-349. doi:10.1054/brst.1999.0076

  • Brimmell, M., Burns, J. S., Munson, P., Mcdonald, L., O'Hare, M. J., Lakhani, S. R. and Packham, G. (1999) High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers. British Journal of Cancer, 81 6: 1042-1051. doi:10.1038/sj.bjc.6690805

  • Lakhani, Sunil R. (1999) The pathology of hereditary breast cancer. Disease Markers, 15 1-3: 113-114. doi:10.1155/1999/459486

  • Lishman, S. C. and Lakhani, S. R. (1999) Atypical lobular hyperplasia and lobular carcinoma in situ: surgical and molecular pathology. Histopathology, 35 3: 195-200. doi:10.1046/j.1365-2559.1999.00815.x

  • Douek, M., Hall-Craggs, M. A., Lakhani, S. R. and Baum, M. (1999) Does preoperative MRI influence the extent of surgical resection in conservative breast cancer surgery?. Breast, 8 2: 84-88. doi:10.1016/S0960-9776(99)90005-X

  • Lakhani, Sunil R. (1999) The transition from hyperplasia to invasive carcinoma of the breast. Journal of Pathology, 187 3: 272-278. doi:10.1002/(SICI)1096-9896(199902)187:3<272::AID-PATH265>3.0.CO;2-2

  • Dunsmuir, W. D., Edwards, S. M., Lakhani, S. R., Young, M., Corbishley, C., Kirby, R. S., Dearnaley, D. P., Dowe, A., Ardern-Jones, A., Kelly, J., CRCBPG UK Familial Prostate Cancer Study Collaborators and Eeles, R. A. (1998) Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. British Journal of Cancer, 78 11: 1430-1433. doi:10.1038/bjc.1998.703

  • Lu, Yong-Jie, Osin, Pinchas, Lakhani, Sunil R., Di Palma, Silvana, Gusterson, Barry A. and Shipley, Janet M. (1998) Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia. Cancer Research, 58 20: 4721-4727.

  • Edwards, Stephen M., Dunsmuir, William D., Gillett, Cheryl E., Lakhani, Sunil R., Corbishley, Catherine, Young, Martin, Kirby, Roger S., Dearnaley, David P., Dowe, Anna, Ardern-Jones, Audrey, Kelly, Jo, CRC/BPG UK Fmilial Prostate Cancer Study Collaborators, Spurr, Nigel, Barnes, Diana M. and Eeles, Rosalind A. (1998) Immunohistochemical expression of BRCA2 protein and allelic loss at the BRCA2 locus in prostate cancer. International Journal of Cancer, 78 1: 1-7. doi:10.1002/(SICI)1097-0215(19980925)78:1<1::AID-IJC1>3.0.CO;2-U

  • Lakhani, Sunil R., Jacquemier, Jocelyne, Sloane, John P, Gusterson, Barry A., Anderson, Thomas J., van de Vijver, Marc J., Farid, Linda M., Venter, Deon, Antoniou, Antonios, Storfer-Isser, Amy, Smyth, Elizabeth, Steel, C. Michael, Haites, Neva, Scott, Rodney J., Goldgar, David, Neuhausen, Susan, Daly, Peter A., Ormiston, Wilma, McManus, Ross, Scherneck, Siegfried, Ponder, Bruce A. J., Ford, Debbie, Peto, Julian, Stoppa-Lyonnet, Dominique, Bignon, Yves-Jean, Struewing, Jeffrey P., Spurr, Nigel K., Bishop, D. Timothy, Klijn, J. G. M., Devilee, Peter, Cornelisse, Cornelisse J., Lasset, Christine, Lenoir, Gilbert, Barkardottir, Rosa Bjork, Egilsson, Valgurdur, Hamann, Ute, Chang-Claude, Jenny, Sobol, Hagay, Weber, Barbara, Stratton, Michael R. and Easton, Douglas F. (1998) Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. Journal of the National Cancer Institute, 90 15: 1138-1145. doi:10.1093/jnci/90.15.1138

  • Douek, Michael, Vaidya, Jayant S., Lakhani, Sunil R., Hall-Craggs, Margaret A., Baum, Michael and Taylor, Irving (1998) Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity?. Lancet, 351 9105: 801-802. doi:10.1016/S0140-6736(98)24011-6

  • Keshtgar, M., Davidson, T., Soundy, V., Lakhani, S. R. and Miller, R. (1997) Breast disease in HIV positive males. The Breast, 6 5: 281-283. doi:10.1016/S0960-9776(97)90005-9

  • Breast Cancer Linkage Consortium*, Lakhani, Sunil R., Easton, Douglas F., Stratton, Michael R., Anderson, Thomas J., Farid, Linda M., Gusterson, B. A., Jaquemier, J., Sloane, J. P., Venter, D., VandeVijver, M. J., Bishop, D. T., Barkardottir, R. B., Bignon, Y. J., Cornelisse, C., ChangClaude, J., Daly, P. A., Devilee, P., Egilsson, V., Ford, D., Goldgar, D., Haites, N., Hamann, U., Klijn, J. G. M., Lasset, C., Lenoir, G., McManus, R., Neuhausen, S., Ormiston, W., Ponder, B. A. J., Peto, J., Steel, C. M., StoppaLyonnet, D., Smyth, E., Sobol, H., Spurr, N. K., Scott, R. J., Scherneck, S., Streuwing, J. P. and Vasen, H. (1997) Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet, 349 9064: 1505-1510.

  • Quinn, Cecily, Ostrowski, Julian, Oxley, Dwight K., Sloane, J. P., Lakhani, S. R., Stratton, M. R., Baum, Michael, Simpson, Jean F., Jensen, Roy A. and Page, David L. (1996) Terminology for carcinoma-in-situ of the breast. Lancet, 347 9010: 1259-1260. doi:10.1016/S0140-6736(96)90774-6

  • Chapman, P., Lakhani, S. R. and Burn, J. (1996) The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas. Oncogene, 12 6: 1375-1377.

  • Lakhani, S. R., Slack, D. N., Hamoudi, R. A., Collins, N., Stratton, M. R. and Sloane, J. P. (1996) Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. Laboratory Investigation, 74 1: 129-135.

  • Cleton-Jansen, A. -M., Collins, N., Lakhani, S. R., Weissenbach, J., Devilee, P., Cornelisse, C. J. and Stratton, M. R. (1995) Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13. British Journal of Cancer, 72 5: 1241-1244. doi:10.1038/bjc.1995.493

  • Lakhani, S. R., Collins, N., Stratton, M. R. and Sloane, J. P. (1995) Atypical ductal hyperplasia of the breast: Clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p. Journal of Clinical Pathology, 48 7: 611-615. doi:10.1136/jcp.48.7.611

  • De Potter, Christian R., Schelfhout, Anne-Marie, Verbeeck, Paul, Lakhani, Sunil R., Brunken, Roland, Van Den Tweel, Jan G., Schauer, Alfred J. and Sloane, John P. (1995) neu Overexpression correlates with extent of disease in large cell ductal carcinoma in situ of the breast. Human Pathology, 26 6: 601-606. doi:10.1016/0046-8177(95)90163-9

  • Collins, N., McManus, R., Wooster, R., Mangion, J., Seal, S., Lakhani, S. R., Ormiston, W., Daly, P. A., Ford, D., Easton, D. F. and Stratton, M. R. (1995) Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene, 10 8: 1673-1675.

  • Stratton, M. R., Collins, N., Lakhani, S. R. and Sloane, J. P. (1995) Loss of heterozygosity in ductal carcinoma in situ of the breast. Journal of Pathology, 175 2: 195-201. doi:10.1002/path.1711750207

  • Lakhani, S. R., Ohare, M. J., Winehouse, J., Gazet, J. C. and Sloane, J. P. (1995) Malignant myoepithelioma (Myoepithelial carcinoma) of the breast - a detailed cytokeratin study. Journal of Clinical Pathology, 48 2: 164-167. doi:10.1136/jcp.48.2.164

  • Lakhani, S. R. and Hall, J. M. (1994) Intravascular malignant lymphomatosis (angiotropic large-cell lymphoma). A case report with evidence for T-cell lineage with polymerase chain reaction analysis. Histopathology, 25 3: 283-286. doi:10.1111/j.1365-2559.1994.tb01331.x

  • Stern, S. C. M., Lakhani, S. and Morgan, S. H. (1994) Renal allograft dysfunction due to vesicoureteric obstruction by nodular malakoplakia. Nephrology, Dialysis, Transplantation, 9 8: 1188-1190.

  • Lakhani, S. R. (1993) Early clinical pathologists: Robert Koch (1843-1910). Journal of Clinical Pathology, 46 7: 596-598.

  • Lakhani, S. R. (1992) Early clinical pathologists: Edward Jenner (1749-1823). Journal of Clinical Pathology, 45 9: 756-758. doi:10.1136/jcp.45.9.756

  • Bolodeoku, J., Lakhani, S., Dunne, F., Ratcliffe, W. A., Clarke, M. and Barron, J. L. (1992) Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease. Journal of Clinical Pathology, 45 6: 541-542. doi:10.1136/jcp.45.6.541

  • Tildsley, G. J. and Lakhani, S. (1992) Early clinical pathologists 4: Rudolf Virchow (1821-1902). Journal of Clinical Pathology, 45 1: 6-7. doi:10.1136/jcp.45.1.6

  • Lakhani, S. (1991) Early clinical pathologists 4: John Hunter (1728-1793). Journal of Clinical Pathology, 44 8: 621-623.

  • Graham, M. D., Lakhani, S. and Gazet, J. C. (1991) Breast conserving surgery in the management of in situ breast carcinoma. European Journal of Surgical Oncology, 17 3: 258-264.

  • Jones, A. L., Millar, J. L., Millar, B. C., Powell, B., Selby, P., Winkley, A., Lakhani, S., Gore, M. E. and McElwain, T. J. (1990) Enhanced anti-tumour activity of carmustine (BCNU) with tumour necrosis factor in vitro and in vivo. British Journal of Cancer, 62 5: 776-780. doi:10.1038/bjc.1990.378

  • Lakhani, S., Chambers, T. J. and Dilly, S. A. (1990) How do we teach pathology? The teaching of pathology at St. George's Hospital Medical School, London. Journal of Pathology, 161 2: 179-181. doi:10.1002/path.1711610214

  • Lakhani, S., Hangartner, J. R. W. and Dilly, S. A. (1990) Choroid-plexus papillomas - immunohistochemical study. Histopathology, 16 4: 419-419. doi:10.1111/j.1365-2559.1990.tb01153.x

  • Lakhani, S., Selby, P., Bliss, J. M., Perren, T. J., Gore, M. E. and McElwain, T. J. (1990) Chemotherapy for malignant melanoma: Combinations and high doses produce more responses without survival benefit. British Journal of Cancer, 61 2: 330-334. doi:10.1038/bjc.1990.65

  • Banerjee, A. K., Lakhani, S., Vincent, M. and Selby, P. (1988) Dose-dependent acute hepatitis associated with administration of high dose methotrexate. Human Toxicology, 7 6: 561-562.

  • Forgeson, G. V., Selby, P., Lakhani, S., Zulian, G., Viner, C., Maitland, J. and McElwain, T. J. (1988) Infused vincristine and adriamycin with high dose methylprednisolone (VAMP) in advanced previously treated multiple myeloma patients. British Journal of Cancer, 58 4: 469-473. doi:10.1038/bjc.1988.243

  • Lakhani, S. and Jones, P. W. (1987) Amebic-colitis - an often misdiagnosed disease. The Practitioner, 231 1438: 1431-1432.

  • Lakhani, S., Leach, R. D. and Jarrett, P. E. M. (1987) Effect of a surgical day unit on waiting lists. Journal of the Royal Society of Medicine, 80 10: 628-629.

  • Banerjee, A., Lakhani, S., McElwain, T. J. and Powles, R. (1987) Intensive therapy for medical complications of haematological malignancy at The Royal Marsden Hospital. Intensive Care Medicine, 13 3: 213-214.

  • Shaunak, S., Lakhani, S. R., Abraham, R. and Maxwell, J. D. (1986) Differences among Asian patients. BMJ, 293 6555: 1169-1169. doi:10.1136/bmj.293.6555.1169

  • Lakhani, S., Davidson, R. N., Hiwaizi, F. and Marsden, R. A. (1984) Razoxane and leukemia. Lancet, 2 8397: 288-289.

  • Carter, D. A., Lakhani, S. and Whitehead, S. A. (1983) Characterization of the inhibitory effects of hyperprolactinaemia on the mechanism controlling LH secretion in chronically ovariectomized rats. Journal of Reproduction and Fertility, 69 1: 57-64.

  • Lakhani, S. and Sondhi, R. (1983) Iron in flour. Lancet, 2 8356: 967-967.

Conference Publication

  • Saunus, Jodi M., Kalita-de Croft, Priyakshi, Lee, F. T., Al-Ejeh, Fares, Lim, Malcolm, Ensbey, Kathleen, Niland, Colleen, Jeffree, Rosalind L., Thomas, Paul, Day, Bryan W., Rose, Stephen, Scott, Andrew M. and Lakhani, Sunil R. (2016). Investigating the Her2-3 dimer as a theranostic target in brain metastases. In: COSA's 43 and ANZBCTG's 38 Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, (114-114). 15-17 November 2016. doi:10.1111/ajco.12646

  • Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (215-215). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

  • Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Reid, Lynne, Holland, Jane D., Birchmeier, Walter, Jat, Parmjit, Brandner, Sebastian, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2015). Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastases. In: Abstracts - 15th International Biennial Congress of the Metastasis Research Society. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (236-236). 28 June - 01 July 2014. doi:10.1007/s10585-015-9708-3

  • Koteeswaran, Raja, Deborah Smith, Ekta Bhutada, Simpson, Peter T., Emma Bartle, Julie Elizabeth Ayre, Galea, Melanie, Joanne Lester, Bowker, Shari and Lakhani, Sunil (2015). Flipping pathology and its impact on learning in second year medical students at University of Queensland, School of Medicine, Australia. In: The 2015 AAMC Medical Education Meeting, Baltimore, Maryland, USA, (). 10-12 November 2015.

  • Saunus, J. M., Quinn, M. C. J., Patch, A. M., Pearson, J. V., Bailey, P. J., Cloonan, N., Nones, K., Miller, D., Mariasegaram, M., Lau, Q., Jeffree, L., Khanna, K. K., Chenevix-Trench, G., Grimmond, S. M., Simpson, P. T., Waddell, N. and Lakhani, S. R. (2015). Genomic and transcriptomic landscapes of human brain metastases. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (236-236). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

  • Nair, Radhika, Teo, Wee Siang, Ye, Sunny, McFarland, Andrea, Harvey, Kate, Roden, Daniel, Junankar, Simon, Baker, Laura, Yang, Jessica, Fluke, Nicola, Millar, Ewan, Mellick, Albert, Naylor, Matthew, Ormandy, Christopher, Lakhani, Sunil, O'Toole, Sandra and Swarbrick, Alexander (2015). The inhibitor of differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (224-224). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

  • Reed, McCart A. E., Kutasovic, J. R., Vargas, A. C., Da Silva, L., Jayanthan, J., Al-Murrani, A., Reid, L. E., Evans, E., Porter, A., Lakhani, S. R. and Simpson, P. T. (2015). The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (239-240). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

  • Junankar, Simon, Baker, Laura, Roden, Daniel, Nair, Radhika, Elsworth, Ben, Lakhani, Sunil, Simpson, Peter, Ormandy C, Chris, O'Toole, Sandra and Swarbrick, Alexander (2014). Id4 Controls Mammary Stem Cells and Marks Breast Cancers with a Stem Cell Like Phenotype. In: Special Issue: Sydney Cancer Conference 2014. Sydney Cancer Conference 2014, University of Sydney, NSW Australia, (15-15). 26 November 2014. doi:10.1111/ajco.12282

  • Lakhani, Sunil R. (2014). Update on WHO breast classification: 2 years on. In: Abstracts: XXXth Congress of the International Academy of Pathology 2014. IAP 2014: 30th Congress of the International Academy of Pathology 2014, Bangkok, Thailand, (S1-S1). 5-10 October, 2014. doi:10.1097/01.PAT.0000454053.47289.16

  • Da Silva, Leonard, McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Reid, Lynne, Fritz, Brian, Cummings, Margaret C, Porter, Alan, Evans, Elizabeth, Lakhani, Sunil R and Simpson, Peter T (2012). Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. In: 24th Lorne Cancer Conference 2012, Lorne, VIC, Australia, (). 9-11 February 2012.

  • Peters, A. A., Simpson, P. T., Bassett, J. J., Lee, J. M., Song, S., Parat, M. O., Lakhani, S. R., Kenny, P. A., Roberts-Thomson, S. J. and Monteith, G. R. (2012). Calcium channel transient receptor potential V6 (TRPV6) as a potential therapeutic target for some breast cancers. In: Abstracts of 24 EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin Ireland, (163-164). 6-9 November 2012.

  • Teo, W., Nair, R., McFarland, A., Ye, S., Mellick, A., Lakhani, S. and Swarbrick, A. (2012). Dissecting the role of the inhibitor of differentiation 1 in breast cancer metastasis and characterization of pathways controlling breast cancer stem cell phenotype. In: Abstracts of the 22nd Biennial Congress of the European Association for Cancer Research. 22nd Biennial Congress of the European Association for Cancer Research, Barcelona Spain, (S37-S37). 07-10 July 2012.

  • Peters, Amelia, Lee, Wei C., Smart, Chanel E., Reid, Lynne, da Silva, Leonard, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2012). Immunohistochemical analysis of PMCA2 expression in normal and malignant human breast tissues. In: Joint ASCEPT-APSA 2012 Conference: Final Program and Abstract Book. Joint ASCEPT-APSA 2012 Conference, Medication Safety, Sydney, Australia, (132-132). 2-5 December 2012.

  • Saunus, Jodi M., Da Silva, Leonard, Momeny, Majid, Morrison, Brian, Lane, Annette, Smart, Chanel, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2012). Role of HER3 in brain metastases from primary breast cancer. In: 24th Lorne Cancer Conference, Lorne, VIC, Australia, (). 9-12 February 2012.

  • Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Vargas, Ana Cristina, Al-Ejeh, Fares, Morrison, Brian, Khanna, Kum Kum, Grimmond, Sean, Chenevix-Trench, Georgia, Jeffree, Rosalind L., Waddell, Nicola, Simpson, Peter T. and Lakhani, Sunil R. (2012). Uncovering molecular mechanisms involved in metastasis to the brain. In: 14th International Biennial Congress of the Metastasis Research Society, Brisbane, QLD, Australia, (). 2-5 September 2012.

  • Lee, W. C., Reid, L., Smart, Chanel, Simpson, P. T., Da Silva, L., Peters, Amelia, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). Expression of the calcium pump PMCA2 in lactating breast and breast cancer. In: ComBio 2011, Cairns, Australia, (). 25-29 September 2011.

  • Vargas, Ana Cristina, Simpson, Peter, McCart Reed, Amy, Lane, Annette, Smart, Chanel, Da Silva, Leonard and Lakhani, Sunil (2011). The Role of Type XI and Type XVII Collagen in Breast Cancer Progression. In: 100th Annual Meeting of the United States and Canadian Academy of Pathology, San Antonio, Texas, United States, (67A-67A). February 6 - March 4 2011.

  • Vargas, Ana Cristina, Simpson, Peter T., McCart Reed, Amy E., Smart, Chanel, Waddell, Nic, Lane, Annette and Lakhani, Sunil (2011). The role of Type XI Collagen in Breast Cancer Progression. In: LICR Translational Oncology Conference, Melbourne, Australia, (). 24-26 October 2011.

  • Peters, Amelia, Simpson, Peter T., Bassett, Johnathon, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues. In: American Association for Cancer Research 102nd Annual Meeting, Orlando, United States, (). 2 - 6 April 2011. doi:10.1158/1538-7445.AM2011-2954

  • Vargas, A. C., Simpson, P., Jayanthan, J., Lane, A., Reid, L., Evans, E., Porter, A. and Lakhani, S. (2010). Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast. In: Histopathology. 28th International Congress of the International-Academy-of-Pathology, Sao Paulo Brazil, (30-30). Oct 10-15, 2010.

  • Lakhani, SR and Simpson, PT (2010). Distinct pathological characteristics of lobular carcinoma. In: Ejc Supplements. European Breast Cancer Conference, Barcelona Spain, (121-121). Mar 24, 2010. doi:10.1016/S1359-6349(10)70242-1

  • Smart, Chanel E., Saunus, Jodi M., Keith, Patricia, Vargas, Ana Cristina, Malik, Neelam, Clarke, Catherine, Simpson, Peter T. and Lakhani, Sunil R. (2010). Shifting phenotypes in primary human mammary epithelial culture. In: Sixth International Conference on Hormonal Oncogenesis, Tokyo, Japan, (). 12-16 September 2010.

  • Shin, S. J., Simpson, P. T., Da Silva, L., Mahalinga-Iyer, J., Lakhani, S. R. and Rosen, P. P. (2008). Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions. In: 97th Annual Meeting of the United States and Canadian Academy of Pathology, Denver, CO, United States, (55A-55A). 1-7 March 2008.

  • Da Silva, L., Parry, S., Keith, P., Lakhani, S. R. and Simpson, P. (2007). Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status. In: Modern Pathology: Annual Meeting Abstracts. United States and Canadian Academy of Pathology 2007 Annual Meeting, San Diego, California, (28A-28A). 24-30 March, 2007.

  • Smart, C. E., Clarke, C., Brooks, K. M., Raghavendra, A., Brewster, B. L., French, J. D., Hetherington, R., Fleming, J. S., Rothnagel, J. A., Wainwright, B., Lakhani, S. R. and Brown, M. A. (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. In: Australian Breast Cancer Conference. Australian Breast Cancer Conference, Melbourne, Australia, (). 2007.

  • Brewster, Brooke, Brooke, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. In: kConFab Familial Breast Cancer Conference. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, (). 21-24 August 2007.

  • Brewster, Brooke, Brooks, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. In: Mammary Gland Biology. Gordon Research Conference: Mammary Gland Biology, Newport, RI, (). 10-15 June 2007.

  • Reis, JS, Pinheiro, C, Lambros, MBK, Milanezi, F, Carvalho, S, Savage, K, Simpson, PT, Jones, C, Swift, S, Mackay, A, Reis, RM, Hornick, JL, Pereira, EM, Baltazar, F, Fletcher, CDM, Ashworth, A, Lakhani, SR and Schmitt, FC (2006). EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. In: Journal of Pathology. 190th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Manchester England, (59-59). Jul 04-07, 2006.

  • Chenevix-Trench, G., Healey, S. C., Lakhani, S., Brinkworth, R. I., KConFab, K. C. F., Marsh, A., Brown, M. A., Easton, D. F., Tavtigian, S., Goldgar, D. E. and Spurdle, A. B. (2005). Genetic and immunohistopathological evaluation of BRCA1 and BRCA2 unclassified variants. In: Proceedings of the Familial Cancer 2005: Research and Practice. Familial Cancer 2005: Research and Practice, Couran Cove, Queensland, (). 30 August - 3 September, 2005.

  • Lakhani, S. R. (1997). Is there a benign to malignant progression?. In: 2nd International Meeting on Current Topics in Breast Cancer Research, Cambridge, England, (93-104). Sep, 1996.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Principal Advisor

  • Doctor Philosophy — Joint Principal Advisor

    Other advisors:

  • Doctor Philosophy — Joint Principal Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision