Professor Peter Nestor

Professor in Neuroscience

Queensland Brain Institute
p.nestor@uq.edu.au
+61 7 334 66389

Overview

Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).

His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia; and improving differential diagnosis between the major categories of neurodegenerative diseases.

He works on development of neuropsychological tests of cognition, both to acccurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occuring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).

Research Interests

  • Cognitive neurology
  • frontotemporal lobar degeneration
  • progressive aphasia
  • Alzheimer's disease
  • Neurodegenerative diseases

Qualifications

  • Doctor of Philosophy in Medicine, University of Cambridge

Publications

  • Schreiber, Stefanie, Spotorno, Nicola, Schreiber, Frank, Acosta-Cabronero, Julio, Kaufmann, Jörn, Machts, Judith, Debska-Vielhaber, Grazyna, Garz, Cornelia, Bittner, Daniel, Hensiek, Nathalie, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J. and Vielhaber, Stefan (2018) Significance of CSF NfL and tau in ALS. Journal of Neurology, 265 11: 2633-2645. doi:10.1007/s00415-018-9043-0

  • Acosta-Cabronero, Julio, Machts, Judith, Schreiber, Stefanie, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Spotorno, Nicola, Kaufmann, Joern, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2018) Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis. Radiology, 289 1: 180112-203. doi:10.1148/radiol.2018180112

  • Boccardi, Marina, Festari, Cristina, Altomare, Daniele, Gandolfo, Federica, Orini, Stefania, Nobili, Flavio, Frisoni, Giovanni B., EANM-EAN Task Force, Agosta, Federica, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter and Walker, Zuzana (2018) Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia. European Journal of Nuclear Medicine and Molecular Imaging, 45 9: 1470-1486. doi:10.1007/s00259-018-4024-1

View all Publications

Publications

Book Chapter

  • Nestor, Peter J. (2017). Frontotemporal dementia. In David Ames, John T. O'Brien and Alistair Burns (Ed.), Dementia 5th ed. (pp. 749-758) Boca Raton, FL, United States: CRC Press.

  • Sajjadi, S. A. and Nestor, P. J. (2016). Bedside assessment of cognition. In Hussain, M. and Schott, J. M. (Ed.), Oxford Textbook of Cognitive Neurology and Dementia (pp. 105-112) Oxford University Press, Oxford, UK: OUP.

  • Nestor, Peter J. and Hodges, John R. (2010). Disturbances of higher cerebral function. In David A. Warrell, Timothy M. Cox and John D. Firth (Ed.), Oxford Textbook of Medicine 5th ed. (pp. 4786-4795) Oxford, United Kingdom: Oxford University Press. doi:10.1093/med/9780199204854.003.2441

  • Nestor, Peter J. (2007). Disorders of memory. In Anthony H.V. Schapira (Ed.), Neurology and Clinical Neuroscience (pp. 43-57) Philadelphia, PA, United States: Elsevier. doi:10.1016/b978-0-323-03354-1.50008-0

  • Nestor, Peter J. (2007). Neuroimaging and other investigative findings. In John R. Hodges (Ed.), Frontotemporal Dementia Syndromes (pp. 134-160) Cambridge, United Kingdom: Cambridge University Press. doi:10.1017/cbo9781316135457.007

Journal Article