Professor Bernard Degnan

Director CMS & UQ Develop. Fellow

School of Biological Sciences
Faculty of Science
b.degnan@uq.edu.au
+61 7 336 52467

Overview

I am the Director of the Centre for Marine Science, and teach and lead a research group in the School of Biological Sciences.

Research Interests

  • Genomes, Development & Evolution
    We are interested in the genomic, cellular and developmental mechanisms that underpin the evolution, formation and functioning of animals. Our lab studies a wide range of coral reef invertebrates - sponges, echinoderms, molluscs and ascidians - some that have traits of economic and environmental value and others that act as models to address fundamental questions in biology and biomedicine.
  • 1. Origin of animal complexity
    We seek to understand the nature and evolution of the genome-encoded rules governing animal systems, including development, stem cells and regeneration.
  • 2. Marine biology and biotechnology
    We undertake basic, strategic and applied research into the molecular, cellular and developmental biology of coral reef invertebrates, including development of novel biocontrol strategies.
  • 3. Genomics and evolution of biomineralization
    We study the formation and patterning of complex biomaterials comprising marine skeletons and shells, some which are of commercial value.

Qualifications

  • PhD (Biochemistry), The University of Queensland
  • Bachelor of Science (Marine Biology), University of California

Publications

  • Sogabe, Shunsuke, Hatleberg, William L., Kocot, Kevin M., Say, Tahsha E., Stoupin, Daniel, Roper, Kathrein E., Fernandez-Valverde, Selene L., Degnan, Sandie M. and Degnan, Bernard M. (2019) Pluripotency and the origin of animal multicellularity. Nature, 570 7762: 519-522. doi:10.1038/s41586-019-1290-4

  • Sebé-Pedrós, Arnau, Chomsky, Elad, Pang, Kevin, Lara-Astiaso, David, Gaiti, Federico, Mukamel, Zohar, Amit, Ido, Hejnol, Andreas, Degnan, Bernard M. and Tanay, Amos (2018) Early metazoan cell type diversity and the evolution of multicellular gene regulation. Nature Ecology & Evolution, 2 7: 1176-1188. doi:10.1038/s41559-018-0575-6

  • Gaiti, Federico, Calcino, Andrew D., Tanurdzic, Miloš and Degnan, Bernard M. (2017) Origin and evolution of the metazoan non-coding regulatory genome. Developmental Biology, 427 2: 193-202. doi:10.1016/j.ydbio.2016.11.013

  • Sebe-Pedros, Arnau, Degnan, Bernard M. and Ruiz-Trillo, Inaki (2017) The origin of Metazoa: a unicellular perspective. Nature Reviews Genetics, 18 8: 498-512. doi:10.1038/nrg.2017.21

  • Gaiti, Federico, Jindrich, Katia, Fernandez-Valverde, Selene L., Roper, Kathrein E., Degnan, Bernard M. and Tanurdzic, Milos (2017) Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity. Elife, 6 . doi:10.7554/eLife.22194

  • Aguilera, Felipe, McDougall, Carmel and Degnan, Bernard M. (2017) Co-option and de novo gene evolution underlie molluscan shell diversity. Molecular Biology and Evolution, 34 4: 779-792. doi:10.1093/molbev/msw294

  • Hall, Michael R., Kocot, Kevin M., Baughman, Kenneth W., Fernandez-Valverde, Selene L., Gauthier, Marie E. A., Hatleberg, William L. ., Krishnan, Arunkumar, McDougall, Carmel, Motti, Cherie A., Shoguchi, Eiichi, Wang, Tianfang, Xiang, Xueyan, Zhao, Min, Bose, Utpal, Shinzato, Chuya, Hisata, Kanako, Fujie, Manabu, Kanda, Miyuki, Cummins, Scott F., Satoh, Noriyuki, Degnan, Sandie M. and Degnan, Bernard M. (2017) The crown-of-thorns starfish genome as a guide for biocontrol of this coral reef pest. Nature, 544 7649: 231-234. doi:10.1038/nature22033

  • Ueda, Nobuo, Richards, Gemma S., Degnan, Bernard M., Kranz, Alexandrea, Adamska, Maja, Croll, Roger P. and Degnan, Sandie M. (2016) An ancient role for nitric oxide in regulating the animal pelagobenthic life cycle: evidence from a marine sponge. Scientific Reports, 6 37546: 37546. doi:10.1038/srep37546

  • Levin, Michal, Anavy, Leon, Cole, Alison G., Winter, Eitan, Mostov, Natalia, Khair, Sally, Senderovich, Naftalie, Kovalev, Ekaterina, Silver, David H., Feder, Martin, Fernandez-Valverde, Selene L., Nakanishi, Nagayasu, Simmons, David, Simakov, Oleg, Larsson, Tomas, Liu, Shang-Yun, Jerafi-Vider, Ayelet, Yaniv, Karina, Ryan, Joseph F., Martindale, Mark Q., Rink, Jochen C., Arendt, Detlev, Degnan, Sandie M., Degnan, Bernard M., Hashimshony, Tamar and Yanai, Itai (2016) The mid-developmental transition and the evolution of animal body plans. Nature, 531 7596: 637-+. doi:10.1038/nature16994

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Featured Publications

  • Sogabe, Shunsuke, Hatleberg, William L., Kocot, Kevin M., Say, Tahsha E., Stoupin, Daniel, Roper, Kathrein E., Fernandez-Valverde, Selene L., Degnan, Sandie M. and Degnan, Bernard M. (2019) Pluripotency and the origin of animal multicellularity. Nature, 570 7762: 519-522. doi:10.1038/s41586-019-1290-4

  • Sebé-Pedrós, Arnau, Chomsky, Elad, Pang, Kevin, Lara-Astiaso, David, Gaiti, Federico, Mukamel, Zohar, Amit, Ido, Hejnol, Andreas, Degnan, Bernard M. and Tanay, Amos (2018) Early metazoan cell type diversity and the evolution of multicellular gene regulation. Nature Ecology & Evolution, 2 7: 1176-1188. doi:10.1038/s41559-018-0575-6

  • Gaiti, Federico, Calcino, Andrew D., Tanurdzic, Miloš and Degnan, Bernard M. (2017) Origin and evolution of the metazoan non-coding regulatory genome. Developmental Biology, 427 2: 193-202. doi:10.1016/j.ydbio.2016.11.013

  • Sebe-Pedros, Arnau, Degnan, Bernard M. and Ruiz-Trillo, Inaki (2017) The origin of Metazoa: a unicellular perspective. Nature Reviews Genetics, 18 8: 498-512. doi:10.1038/nrg.2017.21

  • Gaiti, Federico, Jindrich, Katia, Fernandez-Valverde, Selene L., Roper, Kathrein E., Degnan, Bernard M. and Tanurdzic, Milos (2017) Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity. Elife, 6 . doi:10.7554/eLife.22194

  • Aguilera, Felipe, McDougall, Carmel and Degnan, Bernard M. (2017) Co-option and de novo gene evolution underlie molluscan shell diversity. Molecular Biology and Evolution, 34 4: 779-792. doi:10.1093/molbev/msw294

  • Hall, Michael R., Kocot, Kevin M., Baughman, Kenneth W., Fernandez-Valverde, Selene L., Gauthier, Marie E. A., Hatleberg, William L. ., Krishnan, Arunkumar, McDougall, Carmel, Motti, Cherie A., Shoguchi, Eiichi, Wang, Tianfang, Xiang, Xueyan, Zhao, Min, Bose, Utpal, Shinzato, Chuya, Hisata, Kanako, Fujie, Manabu, Kanda, Miyuki, Cummins, Scott F., Satoh, Noriyuki, Degnan, Sandie M. and Degnan, Bernard M. (2017) The crown-of-thorns starfish genome as a guide for biocontrol of this coral reef pest. Nature, 544 7649: 231-234. doi:10.1038/nature22033

  • Ueda, Nobuo, Richards, Gemma S., Degnan, Bernard M., Kranz, Alexandrea, Adamska, Maja, Croll, Roger P. and Degnan, Sandie M. (2016) An ancient role for nitric oxide in regulating the animal pelagobenthic life cycle: evidence from a marine sponge. Scientific Reports, 6 37546: 37546. doi:10.1038/srep37546

  • Levin, Michal, Anavy, Leon, Cole, Alison G., Winter, Eitan, Mostov, Natalia, Khair, Sally, Senderovich, Naftalie, Kovalev, Ekaterina, Silver, David H., Feder, Martin, Fernandez-Valverde, Selene L., Nakanishi, Nagayasu, Simmons, David, Simakov, Oleg, Larsson, Tomas, Liu, Shang-Yun, Jerafi-Vider, Ayelet, Yaniv, Karina, Ryan, Joseph F., Martindale, Mark Q., Rink, Jochen C., Arendt, Detlev, Degnan, Sandie M., Degnan, Bernard M., Hashimshony, Tamar and Yanai, Itai (2016) The mid-developmental transition and the evolution of animal body plans. Nature, 531 7596: 637-+. doi:10.1038/nature16994

Book Chapter

Journal Article

Conference Publication

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

Completed Supervision