Dr Danielle Borg

Honorary Fellow

Mater Research Institute-UQ
Faculty of Medicine

Overview

Dr Borg is a post-doctoral researcher at the Mater Research Institute-University of Queensland who completed her undergraduate with honours in 2006 (BAppSciHons) at QUT and her PhD in 2012 at the Technische Universität Dresden, Germany. Her interests lie in Diabetes, Islet Biology and Immunology. She has broad research interests and enjoys working with peers from various disciplines. During research career, she has learnt techniques in the fields of Biomaterials, Cell Biology, High Throughput Imaging, Microsurgery, Islet Transplantation, Human Cell Isolation and Biochemistry in a number of European and Australian laboratories. Dr Borg has served on organisation committees for local conferences and national Islet and Diabetes societies. Dr Borg has a particular interest in teaching and supporting undergraduate and RHD students in career progression. She was selected to be the co-chair of the Early Career Research Committee at Mater Reseach Institute-UQ. Dr Borg is an advocate for equity and diversity in science and currently serves on the Gender Equity Working Group at the Mater Research Institute. Connect with her on Twitter @DrDanBorg.

Research Interests

  • New therapeutics for diabetes
  • Immunology and autoimmune diseases
  • Contributors to type 1 diabetes pathogenesis
  • Pancreatic islet transplantation
  • Biomaterial-assisted delivery for cell transplantation

Research Impacts

Dr Borg is an early-career, post-doctoral scientist who is developing track record within the field of diabetes and pancreatic islet biology. She has authored 13 publications in the field of Biomaterial Transplantation, Islet Transplantation, Stem Cell Biology, RAGE/AGE Biology and Diabetes. Her particular expertise lies within pancreatic islet function within type 1 diabetes and her main research interests have concentrated on developing therapeutics that may better treat or inhibit diabetes progression. As a consquence Dr Borg has been invited to review both national grant schemes and original manuscripts in a number of peer-reviewed international journals. Dr Borg enjoys communicating science to the public and has been involved in a number of community projects both in Germany during her PhD and in Australia during her post-doctoral research.

Publications

  • Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017) Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 1: 10-24. doi:10.1080/19382014.2017.1405189

  • Ward, Micheal S, Flemming, Nicole B, Gallo, Linda A, Fotheringham, Amelia K, McCarthy, Domenica A, Zhuang, Aowen, Tang, Peter H, Borg, Danielle J, Shaw, Hannah, Harvie, Benjamin, Briskey, David R, Roberts, Llion A, Plan, Manuel R, Murphy, Michael P, Hodson, Mark P and Forbes, Josephine M (2017) Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific reports, 7 1: 15190. doi:10.1038/s41598-017-15589-x

  • Hardy, Margaret C., Desselle, Mathilde R., the 2016 Catch a Rising Star Consortium, Allen, Jennifer, Andrews, Katherine T., Barrington, Dani J., Borg, Danielle, Butler, Kaylene, Colvin, Rebecca, Cooper, Tarni Louisa, Furlong, Emily, Hugo, Honor, Johnston, Elecia, Iacona, Gwenllian, Kenkel, Carly, Kuempel, Caitlin, Khosla, Amie, Langbecker, Danette, Liddle, Jacki, Lucia, Diana, Lussini, Vanessa, Nazareth, Lynn, Peel, Alison, Saunders, Megan, Smith, Meaghan and Velasquez, Johana Tello (2017) Engaging rural Australian communities in national science week helps increase visibility for women researchers. Royal Society Open Science, 4 10: . doi:10.1098/rsos.170548

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

Conference Publication

  • Fotheringham, A. K., Solon-Biet, S. M., Mcmahon, A. C., Ballard, W. O., Ruohonen, K., Borg, D. J., Raubenheimer, D., Le Couteur, D. G., Simpson, S. J. and Forbes, J. M. (2017). Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging. In: Nephrology. , , (37-37). .

  • McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION. In: Joint Congress of the International-Pancreas-and-Islet-Transplantation-Association, International-Xenotransplantation-Association and Cell-Transplant-Society, Melbourne Australia, (S86-S86). Nov 15-19, 2015.

  • McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-mediated suppression of islet inflammation. In: Xenotransplantation. IPITA/IXA/CTS Joint Congress, Melbourne Australia, (S54-S54). Nov 15-19, 2015.

  • Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. In: Journal of Gene Medicine. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville Australia, (205-205). Apr 29-May 01, 2015.

  • Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. In: 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm Sweden, (S103-S103). Sep 14-18, 2015. doi:10.1007/s00125-015-3687-4

  • Borg, D. J., McCarthy, D., Reeves, P., Ward, M. S., Fotheringham, A. K., Gallo, L. A., Harcourt, B. E., Agrawal, N., Steptoe, R. and Forbes, J. M. (2015). Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes. In: Immunology of Diabetes Society 14th International Congress, Munich, Germany, (). 12-16 April 2015.

  • Borg, Danielle J., Harcourt, Brooke, Ward, Micheal, Tom, Lisa, Fotheringham, Amelia, Mccarthy, Domenica and Forbes, Josephine (2014). Glycation Lowering Therapies Differ in Their Mode of Action in Experimental Autoimmune Diabetes. In: Diabetes. , , (A429-A429). .

  • Harcourt, Brooke E., Leung, Christopher, Borg, Danielle J., Mccarthy, Domenica A., Tom, Lisa, Andrikopoulos, Sofianos, Kieffer, Timothy J. and Forbes, Josephine M. (2014). Receptor for Advanced Glycation End Products Is a Negative Regulator of Glucagon Production. In: Diabetes. , , (A440-A440). .

  • Tesch, G. H., Sourris, K. C., Summers, S. A., Mccarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. and Forbes, J. M. (2014). Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice. In: 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, (41-41). 25–27 August 2014. doi:10.1111/nep.12301

  • Leung, C., Fotheringham, A. K., Zhuang, A., Borg, D. J., Ward, M. S., Coughlan, M. T., Mccarthy, D. A., Gallo, L. A., Harcourt, B. E. and Forbes, J. M. (2014). Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes. In: 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, (62-63). 25–27 August 2014. doi:10.1111/nep.12302

  • Borg, D. J., Yap, F. Y. T., Fotheringham, A. K., Harcourt, B. E., McCarthy, D., Ward, M., Slattery, R., Coughlan, M. T., Kantharidis, P. and Forbes, J. M. (2013). Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner. In: Abstracts of the 49th EASD Annual Meeting. 49th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, (S140-S140). 23 -27 September 2013. doi:10.1007/s00125-013-3012-z

PhD and MPhil Supervision

Current Supervision