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The LACE study is a clinical trial comparing two types of surgery for women with early-stage cancer… Cancer specialists are aware that not only the survival time but also the quality of life is a key… The value of serum CA125 for the development of virtual follow-up strategies for patients with epithelial ovarian cancer: A retrospective study… feMMe: Uterus-preserving treatment of endometrial cancer… Prophylactic surgery and breast cancer… levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps… Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC… Background: Serum CA125 is routinely used in the follow up of ovarian cancer. The objective of the…
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and …
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national …
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Primarily endometrial cancer… Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer… Identifying the regulatory targets of common endometrial cancer risk variants… We and our international Endometrial Cancer Association Consortium collaborators have identified… Gynaecological cancer genetics… -enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research… Excessive exposure to estrogen is a well-established risk factor for endometrial cancer (EC…
After completing his BSc and MSc (Hons) at the University of Canterbury (NZ), Dylan worked for five years as a Research Scientist at Antisoma Research Limited (London, UK), developing antibody-enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research into an …
Large numbers of germline genetic variants have been found to associate with disease. A major roadblock in our understanding of how genetics contribute to disease has been a lack of knowledge of the molecular effects of variants. Thus, the aim of my research program is to use genetic analyses to ass …
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Therapeutic Opportunity in Cancers with Poor Survival… Complex neoantigen prediction in cancers… genome sequencing technologies in biomedical research. In particular large cancer research…
Research officer, Medical Genomics
QIMR Berghofer Medical Research Institute
My research addressed the challenges related to key genomic components in tumour-immune editing variation in cancers with poor survival and predicting the responses to cancer immunotherapies. Characterizing genomic determinants in underlying response and resistance to cancer immunotherapy. Through w …
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Using published datasets, and tissue donated by Brisbane breast cancer patients, we're trying to… Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R… Development of new theranostic agents for metastatic breast cancer surveillance and treatment… Molecular validation of autofluorescence and narrow band imaging of oral cancer resection margins… Most of the time, treatments for early breast cancer successfully prevent metastatic spread, but… Biomarkers of triple-negative breast cancer progression and response to therapy… cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research… BRCA1 is a breast cancer susceptibility gene that is down-regulated in the majority of cases of…
Dr Jodi Saunus is a senior fellow who specialises in translational research on metastatic breast cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research in 2022 to help facilitate patient-focused research at the interface of biomedical R&D and clinical pra …
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modalities of neoadjuvant therapy – results from the AGITG DOCTOR trial and the cancer evolution biobank… Cancer genetics… Barbour. Dr Brosda was awarded a PhD in bioinformatics and cancer genetics from the… set of 89 esophageal cancer samples. The most hypermethylated tumors showed worse patient survival.…
Dr Sandra Brosda is a Research Fellow within the Surgical Oncology group led by Professor Andrew Barbour.
Dr Brosda was awarded a PhD in bioinformatics and cancer genetics from the University of Queensland in November 2020. Her research focused on biomarker discovery and intra-tumour heterogeneity …
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Development of novel therapeutics for melanoma and non-melanoma cancer… Hypoxia-induced stress responses in cancer and cancer stem cells… Skin Cancer… ) promotes stress and death of the organism. However, cancer cells have evolved adaptive mechanisms to…
Researcher Biography
Dr Snehlata Kumari is the head of skin inflammation and immunity laboratory at the Frazer Institute, the University of Queensland in Brisbane, Australia. She is a board member of the Australasian Society for Dermatology Research (ASDR).
After PhD and post-doctoral training in …
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Cell biology: Ran, mitosis and the cancer Lconnection… Cancer chemotherapy… studying cancer, autoimmune diseases, infection and immunity, and the genetic basis of disease… -9 phosphorylation in the regulation of apoptosis during development and in pathological states, including cancer.…
Paul Clarke is Director of the Frazer Institute, a leading translational medical research centre studying cancer, autoimmune diseases, infection and immunity, and the genetic basis of disease. Professor Clarke became Director in 2017 and was previously Associate Dean (Research) in Medicine at the Un …
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Cancers induce immunosuppressive mechanisms, and immunotherapy can either alleviate… early cancer detection and disease monitoring. These specific adaptive immune receptors are essential… Immunotherapy for persisting viral infection and associated cancer… Approaching antigen-presenting cell immunotherapy for cervical cancers using single-cell transcriptomics… health and in cancer. Dr. Tuong was born and raised in Singapore and moved to Brisbane… precancerous neoplasia that can eventuate in cervical cancer. Dendritic cells (DCs) are efficient in priming…
Dr. Kelvin Tuong is a Senior Research Fellow/Group Leader at the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR), Child Health Research Centre. He is interested in single-cell analysis of immune cells and harnessing adaptive immune receptors for understanding immune cell development …
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Salivary exosomes as potential biomarkers in cancer… signalling pathways in diseases such as obesity, diabetes, and ovarian cancer, with a focus on… exosomes mediate cancer progression and metastasis. Given the important biological role played by…
Soumyalekshmi Nair has a degree in Veterinary and Animal Sciences (2009) and a Master of Veterinary Science in Animal Biotechnology (2011) from India. She completed her PhD in 2021 from the Faculty of Medicine, the University of Queensland. In her PhD she investigated the role of extracellular vesi …
The research work on gestational diabetes elucidated the role of extracellular vesicle signalling in the regulation of glucose homeostasis in metabolic conditions. The major impact of my publications has been (1) Identifying the role of extracellular vesicle and their cargo in metabolic conditions a …
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New approaches to immunotherapy for HPV associated cancer… cytotoxic T lymphocyte responses and suggest that they may be the most relevant targets for vaccination against cancers, viruses, and other pathogens.…
Dr Kassianos is a Senior Scientist at the Conjoint Internal Medical Laboratory, Queensland Health. Dr Kassianos has made significant contributions to understanding the cell-cell communication between discrete kidney cell and immune cell populations and the therapeutic potential of targeting this cro …