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IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes… Targeting immunomodulatory molecules on T cells in non-melanoma skin cancer… determined by a balance between pro- and anti- rejection regulatory forces in skin, and the balance…
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Measuring performance in skin cancer practice: the SCARD initiative… Although dermoscopy has been primarily designed for aiding the in vivo diagnosis of skin tumors…
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We aim to identify where exactly in the epithelium (skin and mucosa) vaccines need to be delivered… Hpv16 E7 Transgenic Skin Is Not Rejected in E7 Immunized Mice… Preclinical development of Q2361, a transforming new drug for skin cancer prevention in organ transplant recipients… Dry-coated microprojections can deliver vaccine to abundant antigen-presenting cells in the skin…
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology …
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Expression of HPV16-E7 oncoprotein in skin exacerbates the contact hypersensitivity response to DNCB… Skin immune sentinels: roles and functions of immunoregulatory T cells in HPV16 skin infection in mice… skin grafts expressing the same antigens. In humans, clinical trials have reported successful…
After receiving a PhD on immune regulation from La Sorbonne Universitas in France, Anne-Sophie joined Prof. Ian Frazer’s lab in Australia where she led a highly successful and independent research program on the mechanisms of immune tolerance in human papillomavirus (HPV)-associated lesions in mic …
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Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions… Is there really a viral cause for skin cancer?… and skin cancer. In his time in the Frazer lab, he developed an interest in bioinformatics analyses… hyperproliferative epithelium. Here we examine keratin gene expression profile in skin from mice expressing…
Dr. Kelvin Tuong is a Senior Research Fellow/Group Leader at the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR), Child Health Research Centre. He is interested in single-cell analysis of immune cells and harnessing adaptive immune receptors for understanding immune cell development …
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regulatory cells maintains skin integrity. Despite their importance, little is known about the… Saving your skin: physiology of immune regulation in mammalian lymph nodes… Hair follicles are skin appendages that undergo periods of growth (anagen), regression (catagen…
Dr Andrew Brooks is the Group Leader of the Cytokine Receptor Signalling Group at the University of Queensland Diamantina Institute (UQ DI) within the Translational Research Institute. Andrew completed his Honours research on Flaviviruses in 1996 at the Department of Microbiology and Immunology at J …
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In the last 10 years I have published in journals including Science, Nature Cell Biology, Blood, Oncogene, J Immunol, and Nature Reviews. I have over 1000 citations (Web of Knowledge or over 1500 Google Scholar) with an h-index of 16 (Web of Knowledge) or 19 (Google Scho …
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