Caveolin-1 and the formation of new blood vessels (2009–2010)
To grow and spread, tumors need to be supplied with blood. Preventing the formation of new blood vessels represents a highly promising improvement of cancer treatment. We have shown that the distribution of caveolin-1 is uneven in cells that migrate to initiate new capillaries. We will determine the mechanisms and consequences of this uneven distribution. This will improve our understanding of tumor blood vessel formation and provide the basis for development of new anti cancer treatments.