The University of Queensland

Control of neurosecretion by Munc18 (2010–2012)

Abstract:

Neuronal communication relies on the process of exocytosis by which neurons release a neurotransmitter. Exocytosis is critical for the simplest muscle movement to complex tasks such as learning and memory, and is altered in several neurodegenerative pathologies. We will investigate how the protein Munc18 controls exocytosis. This research will be important for understanding how neurons communicate in health and disease and will be relevant to other processes such as insulin release in diabetes.

Grant type:

NHMRC Project Grant

Researchers:

• 

  Professor Frederic Meunier

  Professor and Academic Snr Gp Lead
  

  Queensland Brain Institute

• 

  Professor Brett Collins

  NHMRC Leadership Fellow - GL
  

  Institute for Molecular Bioscience

Funded by:

National Health and Medical Research Council