The role of the BRCA1 3'UTR in breast cancer (2010–2012)
Basal breast cancer is a subtype of breast cancer that is associated with a particularly poor prognosis. The molecular basis of this subtype of breast cancer is not well understood and is the subject of this research project. We will determine the role of the BRCA1 3'UTR and miRNAs that target the BRCA1 3'UTR in basal breast cancer predisposition and development. The outcome will be improved early diagnosis and the development of more effective therapies.