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Suppressor NKT cell trafficking to epithelial precancer (2010–2012)

Abstract:
The clinical use of the body's immune system to attack existing cancers has met with limited success. Cancer often avoids the immune response by setting up a suppressive environment locally at the tumour. Our study addresses one component of this local environment which involves recruitment of a special subset of suppressive white blood cells - NKT cells. We will establish if drugs can block their recruitment and prevent progression of the cancer.
Grant type:
Cancer Council Queensland
Researchers:

  • Associate Professor Graham Leggatt

    Associate Professor in Immunology
    Frazer Institute
    Faculty of Medicine
    Director (Research Training)
    Research Strategy and Support (Medicine)
    Faculty of Medicine
Funded by:
Cancer Council Queensland