Isaac A. Thangasamy MBBS FRACS (Urol)
Isaac is a urological surgeon with a subspecialty interest in urological cancers of the kidney, bladder and prostate. He also enjoys treating patients with urinary stone disease, bladder dysfunction, prostate conditions and other general urological conditions. After completing his undergraduate medical degree at University of New South Wales, Isaac spent two years as a junior doctor in the northern suburbs of Sydney. Following this, he commenced specialty urology training in Queensland. During this period, he began teaching medical students and is now senior lecturer at the University of Queensland. He also enjoys engaging in the University's state-of-the-art mentorship program. After five years in Queensland, Isaac returned to Sydney to complete his final year of specialty urology training at Nepean Hospital where he developed his robotic surgical skills further. This was followed by a uro-oncology surgery fellowship at the esteemed Peter MacCallum Cancer Centre in Melbourne. Upon completion, he returned to Queensland to take up a position as Director of Urology at Ipswich Hospital, West Moreton Health.
Isaac has a keen interest in surgical education and clinical research. He is currently completing a Doctor of Clinical Surgery through The University of Sydney. His thesis on clinician-related barriers to active surveillance for men with low risk prostate cancer is partially funded by a Movember Quality Improvement research grant.
Journal Article: Navigating systemic therapy for metastatic castration-naïve prostate cancer
Kwan, E. M., Thangasamy, I. A., Teh, J., Alghazo, O., Sathianathen, N. J., Lawrentschuk, N. and Azad, A. A. (2020). Navigating systemic therapy for metastatic castration-naïve prostate cancer. World Journal of Urology, 39 (2), 339-348. doi: 10.1007/s00345-019-03060-7
Journal Article: Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists
Thangasamy, Isaac A., Kwan, Edmond M., Teh, Jiasian, Sathianathen, Niranjan, Alghazo, Omar, Siva, Shankar, Azad, Arun and Murphy, Declan G. (2019). Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists. BJU International, 125 (3), 342-345. doi: 10.1111/bju.14936
Journal Article: Evaluating the effectiveness of an online journal club: experience from the International Urology Journal Club
Thangasamy, Isaac A., Loeb, Stacy, Sathianathen, Niranjan J., Leveridge, Michael, Stork, Brian, Davies, Benjamin J. and Woo, Henry H. (2019). Evaluating the effectiveness of an online journal club: experience from the International Urology Journal Club. European Urology Focus, 7 (2), 482-488. doi: 10.1016/j.euf.2019.10.006
Journal Article: International urology journal club via twitter: 12-month experience
Thangasamy, Isaac A., Leveridge, Michael, Davies, Benjamin J., Finelli, Antonio, Stork, Brian and Woo, Henry H. (2014). International urology journal club via twitter: 12-month experience. European Urology, 66 (1), 112-117. doi: 10.1016/j.eururo.2014.01.034
Thangasamy, Isaac A., Chalasani, Venu, Bachmann, Alexander and Wood, Henry H. (2012). Photoselective vaporisation of the prostate using 80-W and 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis from 2002 to 2012. European Urology, 62 (2), 315-323. doi: 10.1016/j.eururo.2012.04.051
Navigating systemic therapy for metastatic castration-naïve prostate cancer
Kwan, E. M., Thangasamy, I. A., Teh, J., Alghazo, O., Sathianathen, N. J., Lawrentschuk, N. and Azad, A. A. (2020). Navigating systemic therapy for metastatic castration-naïve prostate cancer. World Journal of Urology, 39 (2), 339-348. doi: 10.1007/s00345-019-03060-7
Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists
Thangasamy, Isaac A., Kwan, Edmond M., Teh, Jiasian, Sathianathen, Niranjan, Alghazo, Omar, Siva, Shankar, Azad, Arun and Murphy, Declan G. (2019). Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists. BJU International, 125 (3), 342-345. doi: 10.1111/bju.14936
Thangasamy, Isaac A., Loeb, Stacy, Sathianathen, Niranjan J., Leveridge, Michael, Stork, Brian, Davies, Benjamin J. and Woo, Henry H. (2019). Evaluating the effectiveness of an online journal club: experience from the International Urology Journal Club. European Urology Focus, 7 (2), 482-488. doi: 10.1016/j.euf.2019.10.006
International urology journal club via twitter: 12-month experience
Thangasamy, Isaac A., Leveridge, Michael, Davies, Benjamin J., Finelli, Antonio, Stork, Brian and Woo, Henry H. (2014). International urology journal club via twitter: 12-month experience. European Urology, 66 (1), 112-117. doi: 10.1016/j.eururo.2014.01.034
Thangasamy, Isaac A., Chalasani, Venu, Bachmann, Alexander and Wood, Henry H. (2012). Photoselective vaporisation of the prostate using 80-W and 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis from 2002 to 2012. European Urology, 62 (2), 315-323. doi: 10.1016/j.eururo.2012.04.051
Kam, Jonathan, McClintock, George, Makary, Josh, Jackson, Stuart, Hanna, Bishoy, Grant, Alice, Rahkala, Jake, Arianayagam, Mohan, Canagasingham, Bertram, Ferguson, Richard, Goolam, Ahmed, Winter, Matthew, Jeffery, Nicola, Ko, Raymond, Mehan, Nicholas, Khadra, Mohamed, Thangasamy, Isaac and Varol, Celi (2023). MP61-16 INITIAL CLINICAL TRIAL OF FOCAL LASER ABLATION UTILISING PROFOCAL-R® FOR LOCALISED PROSTATE CANCER. Journal of Urology, 209 (Supplement 4). doi: 10.1097/ju.0000000000003319.16
Kam, Jonathan, Kissane, Luke, Makary, Josh, Hanna, Bishoy, Jackson, Stuart, McClintock, George, Grant, Alice, Arianayagam, Mohan, Canagasingham, Bertram, Ferguson, Richard, Goolam, Ahmed, Winter, Matthew, Ko, Raymond, Mehan, Nicholas, Thangasamy, Isaac, Khadra, Mohamed, Varol, Celi, Azzi, Maria and Jeffery, Nicola (2023). PD15-09 REAL WORLD ASSESSMENT OF MRI PREDICTORS OF RECTAL COMPLICATIONS FOLLOWING TRANSPERINEAL SPACEOAR HYDROGEL INSERTION. Journal of Urology, 209 (Supplement 4). doi: 10.1097/ju.0000000000003262.09
Initial clinical trial of focal laser ablation utilising ProFocal-Rx™ for localised prostate cancer
Kam, J., Mcclintock, G., Hanna, B., Jackson, S., Makary, J., Grant, A., Rahkala, J., Arianayagam, M., Canagasingham, B., Ferguson, R., Goolam, A., Jeffery, N., Winter, M., Khadra, M., Ko, R., Mehan, N., Thangasamy, I. and Varol, C. (2023). Initial clinical trial of focal laser ablation utilising ProFocal-Rx™ for localised prostate cancer. European Urology, 83, S1380. doi: 10.1016/s0302-2838(23)01003-5
Modern Active Surveillance in Prostate Cancer: A Narrative Review
Pattenden, Trent A, Samaranayke, Dhanika, Morton, Andrew, Ong, Wee Loon, Murphy, Declan G, Pritchard, Elizabeth, Evans, Susan, Millar, Jeremy, Chalasani, Venu, Rashid, Prem, Winter, Matthew, Vela, Ian, Pryor, David, Mark, Stephen, Lawrentschuk, Nathan and Thangasamy, Isaac A (2023). Modern Active Surveillance in Prostate Cancer: A Narrative Review. Clinical Genitourinary Cancer, 21 (1), 115-123. doi: 10.1016/j.clgc.2022.09.003
Protocol for mixed-method systematic review of urology in medical school education
Samaranayake, Dhanika, Pattenden, Trent, Morton, Andrew and Thangasamy, Isaac (2022). Protocol for mixed-method systematic review of urology in medical school education. BMJ Open, 12 (12) e061418, 1-4. doi: 10.1136/bmjopen-2022-061418
Khadhouri, Sinan, Gallagher, Kevin M., MacKenzie, Kenneth R., Shah, Taimur T., Gao, Chuanyu, Moore, Sacha, Zimmermann, Eleanor F., Edison, Eric, Jefferies, Matthew, Nambiar, Arjun, Anbarasan, Thineskrishna, Mannas, Miles P., Lee, Taeweon, Marra, Giancarlo, Gómez Rivas, Juan, Marcq, Gautier, Assmus, Mark A., Uçar, Taha, Claps, Francesco, Boltri, Matteo, La Montagna, Giuseppe, Burnhope, Tara, Nkwam, Nkwam, Austin, Tomas, Boxall, Nicholas E., Downey, Alison P., Sukhu, Troy A., Antón-Juanilla, Marta, Rai, Sonpreet ... Zainuddin, Zulkifli (2022). Developing a diagnostic multivariable prediction model for urinary tract cancer in patients referred with Haematuria: results from the IDENTIFY collaborative study. European Urology Focus, 8 (6), 1673-1682. doi: 10.1016/j.euf.2022.06.001
Pattenden, Trent, Samaranayake, Dhanika, Morton, Andrew and Thangasamy, Isaac (2022). Bladder cancer in Aboriginal and Torres Strait Islander people living in Australia: a scoping review protocol. BMJ open, 12 (4) e059144, e059144. doi: 10.1136/bmjopen-2021-059144
Large variation in conservative management for low‐risk prostate cancer in Australia and New Zealand
Ong, Wee Loon, Thangasamy, Isaac, Murphy, Declan, Pritchard, Elizabeth, Evans, Susan, Millar, Jeremy, Chalasani, Venu, Rashid, Prem, Winter, Matthew, Vela, Ian, Pryor, David, Mark, Stephen and Lawrentschuk, Nathan (2022). Large variation in conservative management for low‐risk prostate cancer in Australia and New Zealand. BJU International, 130 (S1), 17-19. doi: 10.1111/bju.15698
Khadhouri, Sinan, Gallagher, Kevin M., MacKenzie, Kenneth R., Shah, Taimur T., Gao, Chuanyu, Moore, Sacha, Zimmermann, Eleanor F., Edison, Eric, Jefferies, Matthew, Nambiar, Arjun, Mannas, Miles P., Lee, Taeweon, Marra, Giancarlo, Lillaz, Beatrice, Gómez Rivas, Juan, Olivier, Jonathan, Assmus, Mark A., Uçar, Taha, Claps, Francesco, Boltri, Matteo, Burnhope, Tara, Nkwam, Nkwam, Tanasescu, George, Boxall, Nicholas E., Downey, Alison P., Lal, Asim A, Antón-Juanilla, Marta, Clarke, Holly, Lau, David H. W. ... Zainuddin, Zulkifli (2021). The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study. BJU International, 128 (4), 440-450. doi: 10.1111/bju.15483
Performance of Ga-68 PSMA PET/CT for diagnosis and grading of local prostate cancer
Kwan, Timothy N., Spremo, Sandra, Teh, Amy Y.M., McHarg, David, Thangasamy, Isaac and Woo, Henry H. (2021). Performance of Ga-68 PSMA PET/CT for diagnosis and grading of local prostate cancer. Prostate International, 9 (2), 107-112. doi: 10.1016/j.prnil.2020.07.008
Quality and readability of online patient information on treatment for erectile dysfunction
Pattenden, Trent A., Raleigh, Rachael A., Pattenden, Elle R. and Thangasamy, Isaac A. (2021). Quality and readability of online patient information on treatment for erectile dysfunction. BJUI Compass, 2 (6) bco2.87, 412-418. doi: 10.1002/bco2.87
Robotic prostatectomy after abandoned open radical prostatectomy—technical aspects and outcomes
O’Connor, E., Koschel, S., Bagguley, D., Sathianathen, N. J., Cumberbatch, M. G., Thangasamy, I. A., Moon, D. and Murphy, D. G. (2020). Robotic prostatectomy after abandoned open radical prostatectomy—technical aspects and outcomes. BJUI Compass, 1 (5) bco2.34, 174-179. doi: 10.1002/bco2.34
Condon, Benjamin, Liskaser, Grace, Thangasamy, Isaac A. and Murphy, Declan G. (2020). Chemotherapy, not androgen receptor-targeted therapy should be used upfront for metastatic hormone-sensitive prostate cancer. CON: Novel oral agents provide an attractive alternative to chemotherapy in metastatic hormone-sensitive prostate cancer. Current Opinion in Urology, 30 (4), 620-622. doi: 10.1097/MOU.0000000000000694
Zhong, Wenjie, Roberts, Matthew, Saad, Jeremy, Thangasamy, Isaac, Arianayagam, Ranjan, Sathianathen, Niranjan, Gendy, Rasha, Goolam, Ahmed, Khadra, Mohamed, Arianayagam, Mohan, Varol, Celi, Ko, Raymond, Canagasingham, Bertram, Ferguson, Richard and Winter, Matthew (2020). A systematic review and meta-analysis of pelvic drain insertion after robot-assisted radical prostatectomy. Journal of Endourology, 34 (4) end.2019.0554, 401-408. doi: 10.1089/end.2019.0554
Sathianathen, Niranjan J., Koschel, Samantha, Thangasamy, Isaac A., Teh, Jiasian, Alghazo, Omar, Butcher, Georgiana, Howard, Harriet, Kapoor, Jada, Lawrentschuk, Nathan, Siva, Shankar, Azad, Arun, Tran, Ben, Bolton, Damien and Murphy, Declan G. (2020). Indirect comparisons of efficacy between combination approaches in metastatic hormone-sensitive prostate cancer: a systematic review and network meta-analysis. European Urology, 77 (3), 365-372. doi: 10.1016/j.eururo.2019.09.004
Teh, Jiasian, Koschel, Samantha, Thangasamy, Isaac, Sathianathen, Niranjan, Murphy, Declan G. and Eapen, Renu (2020). Re: A comparative study of robot-assisted and open radical prostatectomy in 10 790 men treated by highly trained surgeons for both procedures. European Urology, 77 (2), 285-286. doi: 10.1016/j.eururo.2019.08.027
Nouhaud, F. X., Williams, M., Yaxley, W., Cho, J., Perera, M., Thangasamy, I., Esler, R. and Coughlin, G. (2020). Robot-assisted orthotopic “W” ileal neobladder in male patients: step-by-step video-illustrated technique and preliminary outcomes. Journal of Robotic Surgery, 14 (5), 739-744. doi: 10.1007/s11701-020-01048-9
Navigating systemic therapy for metastatic castration-naïve prostate cancer
Kwan, E. M., Thangasamy, I. A., Teh, J., Alghazo, O., Sathianathen, N. J., Lawrentschuk, N. and Azad, A. A. (2020). Navigating systemic therapy for metastatic castration-naïve prostate cancer. World Journal of Urology, 39 (2), 339-348. doi: 10.1007/s00345-019-03060-7
Sathianathen, Niranjan J., Thangasamy, Isaac, Lane, Robert, Condon, Benjamin, Murphy, Declan G., Lawrentschuk, Nathan, Weight, Christopher J. and Lamb, Alastair D. (2020). Corrigendum to “Early Online Attention Can Predict Citation Counts for Urological Publications: The #UroSoMe_Score” [Eur Urol Focus 6 (2020) 458–62] (European Urology Focus (2020) 6(3) (458–462), (S2405456919303372), (10.1016/j.euf.2019.10.015)). European Urology Focus, 7 (3), 668-668. doi: 10.1016/j.euf.2020.05.017
Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists
Thangasamy, Isaac A., Kwan, Edmond M., Teh, Jiasian, Sathianathen, Niranjan, Alghazo, Omar, Siva, Shankar, Azad, Arun and Murphy, Declan G. (2019). Novel agents for metastatic hormone-sensitive prostate cancer - a practice guide for urologists. BJU International, 125 (3), 342-345. doi: 10.1111/bju.14936
Thangasamy, Isaac A., Loeb, Stacy, Sathianathen, Niranjan J., Leveridge, Michael, Stork, Brian, Davies, Benjamin J. and Woo, Henry H. (2019). Evaluating the effectiveness of an online journal club: experience from the International Urology Journal Club. European Urology Focus, 7 (2), 482-488. doi: 10.1016/j.euf.2019.10.006
Thangasamy, Isaac A., Alghazo, Omar and Murphy, Declan G. (2019). Are we ready to adopt the European Association of Urology recommendations on multiparametric magnetic resonance imaging in the early detection of prostate cancer?. Investigative and Clinical Urology, 60 (4), 225-226. doi: 10.4111/icu.2019.60.4.225
Re: Darolutamide in nonmetastatic castration-resistant prostate cancer
Alghazo, Omar, Thangasamy, Isaac, Sathianathen, Niranjan and Murphy, Declan G. (2019). Re: Darolutamide in nonmetastatic castration-resistant prostate cancer. European Urology, 76 (4), 536-537. doi: 10.1016/j.eururo.2019.04.028
Idiopathic partial thrombosis of the corpus cavernosum: an unusual presentation to consider
Ranasinghe, Sachinka V., Chen, Michael, Roberts, Matthew J., Westera, Jurjen, Thangasamy, Isaac and Dunglison, Nigel (2018). Idiopathic partial thrombosis of the corpus cavernosum: an unusual presentation to consider. Journal of Clinical Urology, 12 (1), 205141581774747-77. doi: 10.1177/2051415817747476
Yaxley, Anna J., Yaxley, John W., Thangasamy, Isaac A., Ballard, Emma and Pokorny, Morgan R. (2017). Comparison between target magnetic resonance imaging (MRI) in-gantry and cognitively directed transperineal or transrectal-guided prostate biopsies for Prostate Imaging–Reporting and Data System (PI-RADS) 3–5 MRI lesions. BJU International, 120 (S3), 43-50. doi: 10.1111/bju.13971
Vega Vega, Antonio, Thangasamy, Isaac and Moore, Craig (2017). Free Split-Skin Grafting to Correct Radical Circumcision: An Alternative Solution for an Under-Reported Complication. Urology and Andrology - Open Journal, 1 (2), 32-34. doi: 10.17140/uaoj-1-109
Transcaval ureter: a rare embryological anomaly causing obstructive uropathy
Giddy, Stephanie, Thangasamy, Isaac and Vega Vega, Antonio (2015). Transcaval ureter: a rare embryological anomaly causing obstructive uropathy. BMJ Case Reports, 2015 (feb18 1), bcr2014208076-bcr2014208076. doi: 10.1136/bcr-2014-208076
Tattersall, Timothy Lee, Thangasamy, Isaac A. and Reynolds, Jamie (2014). Bilateral adrenal haemorrhage associated with heparin-induced thrombocytopaenia during treatment of fournier gangrene. BMJ Case Reports, 2014 (oct14 1) 206070, bcr2014206070-bcr2014206070. doi: 10.1136/bcr-2014-206070
Thangasamy, Isaac and Woo, Henry H. (2014). Re: Eija Laurikainen, Antti Valpas, Pauliina Aukee, et al. Five-year Results of a Randomized Trial Comparing Retropubic and Transobturator Midurethral Slings for Stress Incontinence. Eur Urol 2014;65:1109–14. European Urology, 66 (3), e55-e55. doi: 10.1016/j.eururo.2014.04.025
International urology journal club via twitter: 12-month experience
Thangasamy, Isaac A., Leveridge, Michael, Davies, Benjamin J., Finelli, Antonio, Stork, Brian and Woo, Henry H. (2014). International urology journal club via twitter: 12-month experience. European Urology, 66 (1), 112-117. doi: 10.1016/j.eururo.2014.01.034
Woo, Henry, Thangasamy, Isaac and Chalasani, Venu (2013). Photoselective vaporization with the green light laser vs transurethral resection of the prostate for treating benign prostate hyperplasia: a systematic review and meta-analysis. BJU International, 111 (4), E137-E137. doi: 10.1111/j.1464-410X.2013.11397.x
Campbell, Nicholas A., Chung, Amanda S. J., Yoon, Peter D., Thangasamy, Isaac and Woo, Henry H. (2013). Early experience photoselective vaporisation of the prostate using the 180W lithium triborate and comparison with the 120W lithium triborate laser. Prostate International, 1 (1), 42-45. doi: 10.12954/PI.12006
Thangasamy, Isaac A., Chalasani, Venu, Bachmann, Alexander and Wood, Henry H. (2012). Photoselective vaporisation of the prostate using 80-W and 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis from 2002 to 2012. European Urology, 62 (2), 315-323. doi: 10.1016/j.eururo.2012.04.051
Caecal bascule: a rare complication following emergency caesarean section
Thangasamy, Isaac and Silcock, R. (2010). Caecal bascule: a rare complication following emergency caesarean section. Journal of Surgical Case Reports, 2010 (7). doi: 10.1093/jscr/2010.7.8
International urology journal club on Twitter - a growing educational forum
Thangasamy, I., Leveridge, M., Davies, B., Stork, B., Loeb, S. and Woo, H. (2015). International urology journal club on Twitter - a growing educational forum. 68th Annual Scientific Meeting of the Urological Society of Australia and New Zealand, Adelaide, SA Australia, 11-14 April 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.13072
Laparoscopic intervention in a young female with transcaval ureter: a case report
Giddy, S., Thangasamy, I. and Vega, A. Vega (2014). Laparoscopic intervention in a young female with transcaval ureter: a case report. 67th Annual Scientific Meeting of the Urological Society of Australia and New Zealand, Brisbane, QLD Australia, 16-19 March 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.12619
Campbell, N., Chung, A. S. J., Yoon, P. D., Thangasamy, I. and Woo, H. H. (2012). Early experience photoselective vaporisation of the prostate using the 180W lithium triborate and comparison with the 120W lithium triborate laser. 65th Annual Scientific Meeting on Urological-Society-of-Australia-and-New Zealand, Darwin, Australia, 21-24 April 2012. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/j.1464-410X.2012.11073.x