The University of Queensland

Pharmacokinetic and pharmacodynamic tools to increase efficacy

Sinnollareddy, Mahipal G., Cotta, Menino O. and Roberts, Jason A. (2017). Pharmacokinetic and pharmacodynamic tools to increase efficacy. Developments in emerging and existing infectious diseases: Antimicrobial stewardship. (pp. 85-98) edited by Celine Pulcini, Önder Ergönül, Füsun Can and Bojana Beović. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810477-4.00007-6

Pharmacokinetic and pharmacodynamic principles of antimicrobials

Osbert Cotta, Menino and Roberts, Jason (2016). Pharmacokinetic and pharmacodynamic principles of antimicrobials. Antimicrobial stewardship. (pp. 71-78) edited by Matthew Laundy, Mark Gilchrist and Laura Whitney. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780198758792.003.0009

A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20

Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices

Imani, Sahand, Alffenaar, Jan-Willem, Cotta, Menino O., Daveson, Kathryn, van Hal, Sebastiaan, Lau, Cindy, Marriott, Debbie, Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Trethewy, Nicholas, Williams, Paul and Sandaradura, Indy (2020). Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. International Journal of Antimicrobial Agents, 56 (6) 106180, 106180. doi: 10.1016/j.ijantimicag.2020.106180

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731

What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). What are the current approaches to optimising antimicrobial dosing in the intensive care unit?. Pharmaceutics, 12 (7) 638, 1-22. doi: 10.3390/pharmaceutics12070638

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis

Vickers, Mark L., Malacova, Eva, Milinovich, Gabriel J., Harris, Patrick, Eriksson, Lars, Dulhunty, Joel M. and Cotta, Menino O. (2019). Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis. ANZ Journal of Surgery, 89 (10) ans.15393, 1256-1260. doi: 10.1111/ans.15393

Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis

Setiawan, Eko, Wibowo, Yosi I., Setiadi, Adji P., Nurpatria, Yul'aini, Sosilya, Hernycane, Wardhani, Dian K., Cotta, Menino O., Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis. Indonesian Journal of Clinical Pharmacy, 8 (2), 141-156. doi: 10.15416/ijcp.2019.8.2.141

Antibiotic exposure at the site of infection: principles and assessment of tissue penetration

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68.

Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram

Williams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

Mabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8

Risk factors for multidrug-resistant Gram-negative infection in burn patients

Vickers, Mark L., Dulhunty, Joel M., Ballard, Emma, Chapman, Paul, Muller, Michael, Roberts, Jason A. and Cotta, Menino O. (2018). Risk factors for multidrug-resistant Gram-negative infection in burn patients. ANZ Journal of Surgery, 88 (5), 480-485. doi: 10.1111/ans.14144

Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

What are the similarities and differences in antimicrobial prescribing between Australian public and private hospitals?

Cotta, M. O., Chen, C., Tacey, M., James, R. S., Buising, K. L., Marshall, C. and Thursky, K. A. (2016). What are the similarities and differences in antimicrobial prescribing between Australian public and private hospitals?. Internal Medicine Journal, 46 (10), 1182-1188. doi: 10.1111/imj.13209

Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.

Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

Evaluating antimicrobial therapy: how reliable are remote assessors?

Cotta, Menino Osbert, Spelman, Tim, Chen, Caroline, James, Rodney S., Liew, Danny, Thursky, Karin A., Buising, Kirsty L. and Marshall, Caroline (2016). Evaluating antimicrobial therapy: how reliable are remote assessors?. Infection, Disease & Health, 21 (1), 3-10. doi: 10.1016/j.idh.2016.01.002

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

Does critical illness change levofloxacin pharmacokinetics?

Roberts, Jason A., Cotta, Menino Osbert, Cojutti, Piergiorgio, Lugano, Manuela, Rocca, Giorgio D. and Pea, Federico (2016). Does critical illness change levofloxacin pharmacokinetics?. Antimicrobial Agents and Chemotherapy, 60 (3), 1459-1463. doi: 10.1128/AAC.02610-15

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Antimicrobial stewardship in Australian hospitals and other settings

Cairns, Kelly A., Roberts, Jason A., Cotta, Menino O. and Cheng, Allen C. (2015). Antimicrobial stewardship in Australian hospitals and other settings. Infectious Diseases and Therapy, 4 (Supp.1), 27-38. doi: 10.1007/s40121-015-0083-9

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool

James, Rodney, Upjohn, Lydia, Cotta, Menino, Luu, Susan, Marshall, Caroline, Buising, Kirsty and Thursky, Karin (2015). Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool. Journal of Antimicrobial Chemotherapy, 70 (6) dkv047, 1912-1918. doi: 10.1093/jac/dkv047

Post-operative iatrogenic pneumothorax and associated mortality: lessons learnt

Cotta, Menino Osbert, Tan, Shu Yi, Cotta, Maria Virginia Pereira E. and Bowers, Kaye (2015). Post-operative iatrogenic pneumothorax and associated mortality: lessons learnt. ANZ Journal of Surgery, 85 (5), 389-390. doi: 10.1111/ans.12955

Implementing antimicrobial stewardship in the Australian private hospital system: a qualitative study

Cotta, Menino O., Robertson, Megan S., Marshall, Caroline, Thursky, Karin A., Liew, Danny and Buising, Kirsty L. (2015). Implementing antimicrobial stewardship in the Australian private hospital system: a qualitative study. Australian Health Review, 39 (3), 315-322. doi: 10.1071/AH14111

Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831

An experience with dracunculiasis in Melbourne, Australia

Cotta, Menino O., Cotta, Maria V. Pereira E., Darby, Jonathan, Sutherland, Tom R. and Sheorey, Harsha (2014). An experience with dracunculiasis in Melbourne, Australia. Pathology, 46 (7), 652-653. doi: 10.1097/PAT.0000000000000169

Attitudes towards antimicrobial stewardship: results from a large private hospital in Australia

Cotta, Menino O., Robertson, Megan S., Tacey, Mark, Marshall, Caroline, Thursky, Karin A., Liew, Danny and Buising, Kirsty L. (2014). Attitudes towards antimicrobial stewardship: results from a large private hospital in Australia. Healthcare Infection, 19 (3), 89-94. doi: 10.1071/HI14008

Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals

Cotta, M. O., Robertson, M. S., Upjohn, L. M., Marshall, C., Liew, D. and Buising, K. L. (2014). Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals. Internal Medicine Journal, 44 (3), 240-246. doi: 10.1111/imj.12353

Antimicrobial stewardship of β-lactams in intensive care units

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014). Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 (5), 581-595. doi: 10.1586/14787210.2014.902308

Antimicrobial stewardship in Victorian hospitals: a statewide survey to identify current gaps

James, Rodney S., McIntosh, Kylle A., Luu, Susan B., Cotta, Menino O., Marshall, Caroline, Thursky, Karin A. and Buising, Kirsty L. (2013). Antimicrobial stewardship in Victorian hospitals: a statewide survey to identify current gaps. Medical Journal of Australia, 199 (10), 692-695. doi: 10.5694/mja13.10422

Development of an electronic case record form (AU-Crit) for antimicrobial stewardship program initiation

Pathiraj, John Preshanth Kumar, Hande, Manjunatha H., Varma, Murulidhar, Mukhyopadhay, Chiranjoy, Jathanna, Roshan David, Cotta (Os), Menino Osbert and Ghaffur, Abdul (2016). Development of an electronic case record form (AU-Crit) for antimicrobial stewardship program initiation. 5th International Australasian College for Infection Prevention and Control 2016, Melbourne, VIC, Australia, 20-23 November 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2016.09.039

The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units

Tabah, A., Roberts, J., De Waele, J. J., Lipman, J., Zahar, J. R., Cotta, M. O., Barton, G. and Timsit, J. -F. (2014). The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units. 27th Annual Congress of the European Society of Intensive Care Medicine (ESICM), Barcelona, Spain, 27 September-1 October 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00134-014-3451-0