I am an academic paediatric neurologist, clinical researcher, and specialist in acquired brain injury in children and adolescence. I studied at the University of Edinburgh and British Columbia before taking up my first academic position at the University of Calgary in 2002. Here I developed and directed the Traumatic Brain Injury and Concussion Research Program at the Alberta Children's Hospital and where I cemented my interest in the biology and treatment of children with brain injuries. I have extensive clinical research experience, devising and overseeing clinical trials in children both nationally and internationally. I moved to the Child Health Research Centre at the University of Queensland, Australia in October 2017 and joined the Queensland Paediatric Rehabilitation Service and Queensland Cerebral Palsy Rehabililation Centre to facilitate research into improving the health outcomes of children with acquired brain injury in Queensland and Australia.
My research focuses on the neurobiological signatures and treatment of subtle neurological dysfunction in mild traumatic brain injury and concussion, especially the behavioural and cognitive impairments that are found in post-concussion syndrome. I use multimodal neurological assessments to do this. My research explores combining neuroimaging and neurophysiological investigations, including perfusion studies using MRI (ASL-fMRI) and transcranial magnetic stimulation to help us understand the changes in the brain in children who are slow to recovery following a concussion. This is to help us develop and assess more effective and tailored treatments for children with concussion and traumatic brain injury. I explore novel therapies for children with persistent post-concussive symptoms in clinical trials including the use of neuraceuticals, pharmacotherapies, and non-invasive brain stimulation treatment.
I am the director of the newly-established KidStim Lab at the Child Health Research Centre. This is the first non-invasive neuromodulation facility aimed at improving the health outcomes of children with brain injury in Australia and is led by a mulitdisciplinary team of clinicians and scientists from Brisbane bring a unique clinical and scientific knowledge-base to help achieve our goals. Rehabilitation therapy in combination with repetitive transcranial direct current stimulation (rTMS) and other direct current stimulation modalities (e.g. tDCS) will be explored. It also offers the potential for treatment of the mood and behavioural disorders (e.g. depression and anxiety) commonly seen after brain injury but also so disruptive to the life of the normally developing teenager.
Journal Article: Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months
Banoei, Mohammad M., Lee, Chel Hee, Hutchison, James, Panenka, William, Wellington, Cheryl, Wishart, David S., Winston, Brent W., Joffe, Ari, Barlow, Karen, Yeates, Keith, Esser, Michael, Winston, Brent, Wellington, Cheryl, Torres, Ivan, Walley, Keith, Silverberg, Noah, Carrion, Priscilla, Doan, Quynh, Stukas, Sophie, Vercauteren, Susan, Panenka, Will, Aquino, Angela, Lorelei, Audas, Clarke, David, Martin, Kelly, Davis, Adrienne, Colantonio, Angela, Wheeler, Anne, Guerguerian, Anne-Marie ... Lacroix, Jacques (2023). Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months. Critical Care, 27 (1) 295. doi: 10.1186/s13054-023-04573-9
Yeates, Keith Owen, Räisänen, Anu M, Premji, Zahra, Debert, Chantel T, Frémont, Pierre, Hinds, Sidney, Smirl, Jonathan D, Barlow, Karen, Davis, Gavin A, Echemendia, Ruben J, Feddermann-Demont, Nina, Fuller, Colm, Gagnon, Isabelle, Giza, Christopher C, Iverson, Grant L, Makdissi, Michael and Schneider, Kathryn J (2023). What tests and measures accurately diagnose persisting post-concussive symptoms in children, adolescents and adults following sport-related concussion? A systematic review. British Journal of Sports Medicine, 57 (12), 780-788. doi: 10.1136/bjsports-2022-106657
Journal Article: Structural brain network lateralization across childhood and adolescence
Craig, Brandon T., Geeraert, Bryce, Kinney‐Lang, Eli, Hilderley, Alicia J., Yeates, Keith O., Kirton, Adam, Noel, Melanie, MacMaster, Frank P., Bray, Signe, Barlow, Karen M., Brooks, Brian L., Lebel, Catherine and Carlson, Helen L. (2023). Structural brain network lateralization across childhood and adolescence. Human Brain Mapping, 44 (4), 1711-1724. doi: 10.1002/hbm.26169
(2022–2026) Murdoch Childrens Research Institute
(2022–2025) Curtin University
(2022–2024) NHMRC MRFF Traumatic Brain Injury Mission
Helping children to flourish by improving sleep after childhood traumatic brain injury
Doctor Philosophy
Using Non-Invasive Brain Stimulation to "Rewire" the Brain After Childhood Brain Injury
Doctor Philosophy
Exploring neuromodulation therapies for post concussive symptoms in children
Using mulitmodal neuroimaging to explore the neurobiology of post-concussion syndrome in children
Clinical care pathways following concussion - using technology to guide the way
Cerebral activation of attention and working memory in traumatic brain injury
Stein, Athena, Iyer, Kartik K. and Barlow, Karen M. (2022). Cerebral activation of attention and working memory in traumatic brain injury. Diagnosis and Treatment of Traumatic Brain Injury. (pp. 151-167) London, United Kingdom: Academic Press. doi: 10.1016/b978-0-12-823347-4.00025-7
Pediatric Concussion Diagnosis, Management, and Rehabilitation
Samuel, Tina L. and Barlow, Karen M. (2019). Pediatric Concussion Diagnosis, Management, and Rehabilitation. Traumatic Brain Injury: A Clinician’s Guide to Diagnosis, Management, and Rehabilitation: Second Edition. (pp. 383-397) Springer International Publishing. doi: 10.1007/978-3-030-22436-3_19
Transcranial magnetic stimulation neurophysiology of pediatric traumatic brain injury
Barlow, K. M. and Seeger, T. A. (2016). Transcranial magnetic stimulation neurophysiology of pediatric traumatic brain injury. Pediatric brain stimulation: mapping and modulating the developing brain. (pp. 345-374) edited by Adam Kirton and Donald L. Gilbert. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-802001-2.00017-5
Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months
Banoei, Mohammad M., Lee, Chel Hee, Hutchison, James, Panenka, William, Wellington, Cheryl, Wishart, David S., Winston, Brent W., Joffe, Ari, Barlow, Karen, Yeates, Keith, Esser, Michael, Winston, Brent, Wellington, Cheryl, Torres, Ivan, Walley, Keith, Silverberg, Noah, Carrion, Priscilla, Doan, Quynh, Stukas, Sophie, Vercauteren, Susan, Panenka, Will, Aquino, Angela, Lorelei, Audas, Clarke, David, Martin, Kelly, Davis, Adrienne, Colantonio, Angela, Wheeler, Anne, Guerguerian, Anne-Marie ... Lacroix, Jacques (2023). Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months. Critical Care, 27 (1) 295. doi: 10.1186/s13054-023-04573-9
Yeates, Keith Owen, Räisänen, Anu M, Premji, Zahra, Debert, Chantel T, Frémont, Pierre, Hinds, Sidney, Smirl, Jonathan D, Barlow, Karen, Davis, Gavin A, Echemendia, Ruben J, Feddermann-Demont, Nina, Fuller, Colm, Gagnon, Isabelle, Giza, Christopher C, Iverson, Grant L, Makdissi, Michael and Schneider, Kathryn J (2023). What tests and measures accurately diagnose persisting post-concussive symptoms in children, adolescents and adults following sport-related concussion? A systematic review. British Journal of Sports Medicine, 57 (12), 780-788. doi: 10.1136/bjsports-2022-106657
Structural brain network lateralization across childhood and adolescence
Craig, Brandon T., Geeraert, Bryce, Kinney‐Lang, Eli, Hilderley, Alicia J., Yeates, Keith O., Kirton, Adam, Noel, Melanie, MacMaster, Frank P., Bray, Signe, Barlow, Karen M., Brooks, Brian L., Lebel, Catherine and Carlson, Helen L. (2023). Structural brain network lateralization across childhood and adolescence. Human Brain Mapping, 44 (4), 1711-1724. doi: 10.1002/hbm.26169
Yeates, Keith Owen, Barlow, Karen M., Wright, Bruce, Tang, Ken, Barrett, Olesya, Berdusco, Edward, Black, Amanda M., Clark, Brenda, Conradi, Alf, Godfrey, Heather, Kolstad, Ashley T., Ly, Anh, Mikrogianakis, Angelo, Purser, Ross, Schneider, Kathryn, Stang, Antonia S., Zemek, Roger, Zwicker, Jennifer D. and Johnson, David W. (2023). Health care impact of implementing a clinical pathway for acute care of pediatric concussion: a stepped wedge, cluster randomised trial. Canadian Journal of Emergency Medicine, 25 (7), 627-636. doi: 10.1007/s43678-023-00530-1
Stein, Athena and Barlow, Karen (2023). Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol. Brain Stimulation, 16 (1), 300. doi: 10.1016/j.brs.2023.01.540
Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Maas, Andrew I R, Menon, David K, Manley, Geoffrey T, Abrams, Mathew, Åkerlund, Cecilia, Andelic, Nada, Aries, Marcel, Bashford, Tom, Bell, Michael J, Bodien, Yelena G, Brett, Benjamin L, Büki, András, Chesnut, Randall M, Citerio, Giuseppe, Clark, David, Clasby, Betony, Cooper, D Jamie, Czeiter, Endre, Czosnyka, Marek, Dams-O'Connor, Kristen, De Keyser, Véronique, Diaz-Arrastia, Ramon, Ercole, Ari, Van Essen, Thomas A, Falvey, Eanna, Ferguson, Adam R, Figaji, Anthony, Fitzgerald, Melinda, Foreman, Brandon ... Zumbo, Fabrizio (2022). Traumatic brain injury: progress and challenges in prevention, clinical care, and research. The Lancet Neurology, 21 (11), 1004-1060. doi: 10.1016/S1474-4422(22)00309-X
Fitzgerald, Melinda, Ponsford, Jennie, Lannin, Natasha A., O'Brien, Terence J., Cameron, Peter, Cooper, D. James, Rushworth, Nick, Gabbe, Belinda, AUS-TBI Investigators, Barlow, Karen and Bellapart, Judith (2022). AUS-TBI: The Australian Health Informatics Approach to Predict Outcomes and Monitor Intervention Efficacy after Moderate-to-Severe Traumatic Brain Injury. Neurotrauma Reports, 3 (1), 217-223. doi: 10.1089/neur.2022.0002
Ly, Anh, Zemek, Roger, Wright, Bruce, Zwicker, Jennifer, Schneider, Kathryn, Mikrogianakis, Angelo, Conradi, Alf, Johnson, David, Clark, Brenda, Barlow, Karen, Burey, Joseph, Kolstad, Ash and Yeates, Keith Owen (2021). “What is the actual goal of the pathway?”: examining emergency department physician and nurse perspectives on the implementation of a pediatric concussion pathway using the theoretical domains framework. BMC Health Services Research, 21 (1) 119, 119. doi: 10.1186/s12913-021-06110-2
Post‐traumatic headache: an unmet medical need
Barlow, Karen M. (2021). Post‐traumatic headache: an unmet medical need. Headache: The Journal of Head and Face Pain, 61 (10), 1465-1466. doi: 10.1111/head.14241
Barlow, Karen M., Iyer, Kartik, Yan, Tingting, Scurfield, Alex, Carlson, Helen and Wang, Yang (2021). Cerebral blood flow predicts recovery in children with persistent post-concussion symptoms after mild traumatic brain injury. Journal of Neurotrauma, 38 (16), 2275-2283. doi: 10.1089/neu.2020.7566
Enticott, Peter G, Barlow, Karen, Guastella, Adam J, Licari, Melissa K, Rogasch, Nigel C, Middeldorp, Christel M, Clark, Scott R, Vallence, Ann-Maree, Boulton, Kelsie A, Hickie, Ian B, Whitehouse, Andrew J O, Galletly, Cherrie, Alvares, Gail A, Fujiyama, Hakuei, Heussler, Helen, Craig, Jeffrey M, Kirkovski, Melissa, Mills, Natalie T, Rinehart, Nicole J, Donaldson, Peter H, Ford, Talitha C, Caeyenberghs, Karen, Albein-Urios, Natalia, Bekkali, Soukayna and Fitzgerald, Paul B (2021). Repetitive transcranial magnetic stimulation (rTMS) in autism spectrum disorder: protocol for a multicentre randomised controlled clinical trial. BMJ Open, 11 (7) e046830, 1-9. doi: 10.1136/bmjopen-2020-046830
Australian and New Zealand guideline for mild to moderate head injuries in children
Babl, Franz E, Tavender, Emma, Ballard, Dustin W, Borland, Meredith L, Oakley, Ed, Cotterell, Elizabeth, Halkidis, Lambros, Goergen, Stacy, Davis, Gavin A, Perry, David, Anderson, Vicki, Barlow, Karen M, Barnett, Peter, Bennetts, Scott, Bhamjee, Roisin, Cole, Joanne, Craven, John, Haskell, Libby, Lawton, Ben, Lithgow, Anna, Mullen, Glenda, O'Brien, Sharon, Paproth, Michelle, Wilson, Catherine L, Ring, Jenny, Wilson, Agnes, Leo, Grace SY and Dalziel, Stuart R (2021). Australian and New Zealand guideline for mild to moderate head injuries in children. Emergency Medicine Australasia, 33 (2), 214-231. doi: 10.1111/1742-6723.13722
Stein, Athena, Iyer, Kartik K., Khetani, Aneesh M. and Barlow, Karen M. (2021). Changes in working memory-related cortical responses following pediatric mild traumatic brain injury: a longitudinal fMRI study. Journal of Concussion, 5. doi: 10.1177/20597002211006541
Concussion burden, recovery, and risk factors in elite youth ice hockey players
Schneider, Kathryn J., Nettel-Aguirre, Alberto, Palacios-Derflingher, Luz, Mrazik, Martin, Brooks, Brian L., Woollings, Kaikanani, Blake, Tracy, McKay, Carly, Lebrun, Constance, Barlow, Karen, Taylor, Kirsten, Lemke, Nicole, Meeuwisse, Willem H. and Emery, Carolyn A. (2021). Concussion burden, recovery, and risk factors in elite youth ice hockey players. Clinical Journal of Sport Medicine, 31 (1), 70-77. doi: 10.1097/JSM.0000000000000673
Ofoghi, Zahra, Rohr, Christiane S., Dewey, Deborah, Bray, Signe, Yeates, Keith Owen, Noel, Melanie and Barlow, Karen M. (2021). Functional connectivity of the anterior cingulate cortex with pain-related regions in children with post-traumatic headache. Cephalalgia Reports, 4. doi: 10.1177/25158163211009477
Neural signatures of sleep recovery following melatonin treatment for pediatric concussion
Iyer, Kartik, Zalesky, Andrew, Cocchi, Luca and Barlow, Karen Maria (2020). Neural signatures of sleep recovery following melatonin treatment for pediatric concussion. Journal of Neurotrauma, 37 (24), 2647-2655. doi: 10.1089/neu.2020.7200
Barlow, Karen Maria, Kirk, Valerie, Brooks, Brian, Esser, Michael Joachim, Yeates, Keith Owen, Zemek, Roger, Kirton, Adam, Mikrogianakis, Angelo, MacMaster, Frank, Nettel-Aguirre, Alberto, Hutchison, James, Turley, Brenda, Cameron, Candice, Hill, Michael, Boyd, Roslyn and Dewey, Deborah (2020). Efficacy of melatonin for sleep disturbance in children with persistent post-concussion symptoms: secondary analysis of a randomized controlled trial. Journal of Neurotrauma, 38 (8), 950-959. doi: 10.1089/neu.2020.7154
Huth, Samuel Fergus, Slater, Anthony, Waak, Michaela, Barlow, Karen Maria and Raman, Sainath (2020). Predicting neurological recovery following traumatic brain injury in children: a systematic review of prognostic models. Journal of Neurotrauma, 37 (20) neu.2020.7158, 2141-2149. doi: 10.1089/neu.2020.7158
Brooks, Brian L., Virani, Shane, Khetani, Aneesh, Carlson, Helen, Jadavji, Zeanna, Mauthner, Micaela, Low, Trevor A., Plourde, Vickie, MacMaster, Frank P., Bray, Signe, Harris, Ashley D., Lebel, Catherine, Lebel, R. Marc, Esser, Michael J., Yeates, Keith Owen and Barlow, Karen M. (2020). Functional magnetic resonance imaging study of working memory several years after pediatric concussion. Brain Injury, 34 (7), 1-10. doi: 10.1080/02699052.2020.1753240
George, Joanne M., Pagnozzi, Alex M., Bora, Samudragupta, Boyd, Roslyn N., Colditz, Paul B., Rose, Stephen E., Ware, Robert S., Pannek, Kerstin, Bursle, Jane E., Fripp, Jurgen, Barlow, Karen, Iyer, Kartik, Leishman, Shaneen J. and Jendra, Rebecca L. (2020). Prediction of childhood brain outcomes in infants born preterm using neonatal MRI and concurrent clinical biomarkers (PREBO-6): study protocol for a prospective cohort study. BMJ Open, 10 (5) e036480, e036480. doi: 10.1136/bmjopen-2019-036480
Zewdie, E., Ciechanski, P., Kuo, H. C., Giuffre, A., Kahl, C., King, R., Cole, L., Godfrey, H., Seeger, T., Swansburg, R., Damji, O., Rajapakse, T., Hodge, J., Nelson, S., Selby, B., Gan, L., Jadavji, Z., Larson, J. R., MacMaster, F., Yang, J. F., Barlow, K., Gorassini, M., Brunton, K. and Kirton, A. (2020). Safety and tolerability of transcranial magnetic and direct current stimulation in children: prospective single center evidence from 3.5 million stimulations. Brain Stimulation, 13 (3), 565-575. doi: 10.1016/j.brs.2019.12.025
Barlow, Karen M., Girgulis, Katherine A., Goldstein, Genevieve, Crowe, Erica G., Vo, Mai K., Su, Peter, Esser, Michael J., Dewey, Deborah and Kirk, Valerie G. (2020). Sleep parameters and overnight urinary melatonin production in children with persistent post-concussion symptoms. Pediatric Neurology, 105, 27-34. doi: 10.1016/j.pediatrneurol.2019.11.006
Efficacy of melatonin in children With postconcussive symptoms: a randomized clinical trial
Barlow, Karen M., Brooks, Brian L., Esser, Michael J., Kirton, Adam, Mikrogianakis, Angelo, Zemek, Roger L., MacMaster, Frank P., Nettel-Aguirre, Alberto, Yeates, Keith Owen, Kirk, Valerie, Hutchison, James S., Crawford, Susan, Turley, Brenda, Cameron, Candice, Hill, Michael D., Samuel, Tina, Buchhalter, Jeffrey, Richer, Lawrence, Platt, Robert, Boyd, Roslyn and Dewey, Deborah (2020). Efficacy of melatonin in children With postconcussive symptoms: a randomized clinical trial. Pediatrics, 145 (4) e20192812, e20192812. doi: 10.1542/peds.2019-2812
Ofoghi, Zahra, Dewey, Deborah and Barlow, Karen M. (2020). A Systematic Review of Structural and Functional Imaging Correlates of Headache or Pain after Mild Traumatic Brain Injury. Journal of Neurotrauma, 37 (7) neu.2019.6750, 907-923. doi: 10.1089/neu.2019.6750
Default mode network anatomy and function is linked to pediatric concussion recovery
Iyer, Kartik K., Zalesky, Andrew, Barlow, Karen M. and Cocchi, Luca (2019). Default mode network anatomy and function is linked to pediatric concussion recovery. Annals of Clinical and Translational Neurology, 6 (12) acn3.50951, 2544-2554. doi: 10.1002/acn3.50951
Tomfohr-Madsen, Lianne, Madsen, Joshua W., Bonneville, Dominique, Virani, Shane, Plourde, Vickie, Barlow, Karen M., Yeates, Keith Owen and Brooks, Brian L. (2019). A pilot randomized controlled trial of cognitive-behavioral therapy for insomnia in adolescents with persistent postconcussion symptoms. Journal of Head Trauma Rehabilitation, 35 (2), 1-E112. doi: 10.1097/HTR.0000000000000504
Khetani, Aneesh, Rohr, Christiane S., Sojoudi, Alireza, Bray, Signe and Barlow, Karen M. (2019). Alteration in cerebral activation during a working memory task after pediatric mild traumatic brain injury: a prospective controlled cohort study. Journal of Neurotrauma, 36 (23) neu.2018.6117, 3274-3283. doi: 10.1089/neu.2018.6117
Yeates, Keith Owen, Tang, Kenneth, Barrowman, Nick, Freedman, Stephen B., Gravel, Jocelyn, Gagnon, Isabelle, Sangha, Gurinder, Boutis, Kathy, Beer, Darcy, Craig, William, Burns, Emma, Farion, Ken J., Mikrogianakis, Angelo, Barlow, Karen, Dubrovsky, Alexander S., Meeuwisse, Willem, Gioia, Gerard, Meehan, William P., Beauchamp, Miriam H., Kamil, Yael, Grool, Anne M., Hoshizaki, Blaine, Anderson, Peter, Brooks, Brian L., Vassilyadi, Michael, Klassen, Terry, Keightley, Michelle, Richer, Lawrence, DeMatteo, Carol ... Zemek, Roger (2019). Derivation and initial validation of clinical phenotypes of children presenting with concussion acutely in the emergency department: latent class analysis of a multi-center, prospective cohort, observational study. Journal of Neurotrauma, 36 (11), 1758-1767. doi: 10.1089/neu.2018.6009
King, Regan, Kirton, Adam, Zewdie, Ephrem, Seeger, Trevor A., Ciechanski, Patrick and Barlow, Karen M. (2019). Longitudinal Assessment of Cortical Excitability in Children and Adolescents With Mild Traumatic Brain Injury and Persistent Post-concussive Symptoms. Frontiers in Neurology, 10 (MAY) 451, 451. doi: 10.3389/fneur.2019.00451
King, Regan, Grohs, Melody N., Kirton, Adam, Lebel, Catherine, Esser, Michael J. and Barlow, Karen M. (2019). Microstructural neuroimaging of white matter tracts in persistent post-concussion syndrome: a prospective controlled cohort study. NeuroImage: Clinical, 23 101842, 101842. doi: 10.1016/j.nicl.2019.101842
Relating brain connectivity with persistent symptoms in pediatric concussion
Iyer, Kartik K., Barlow, Karen M., Brooks, Brian, Ofoghi, Zahra, Zalesky, Andrew and Cocchi, Luca (2019). Relating brain connectivity with persistent symptoms in pediatric concussion. Annals of Clinical and Translational Neurology, 6 (5) acn3.764, 954-961. doi: 10.1002/acn3.764
Primum non nocere: a call for balance when reporting on CTE
Stewart, William, Allinson, Kieren, Al-Sarraj, Safa, Bachmeier, Corbin, Barlow, Karen, Belli, Antonio, Burns, Mark P, Carson, Alan, Crawford, Fiona, Dams-O'Connor, Kristen, Diaz-Arrastia, Ramon, Dixon, C Edward, Edlow, Brian L, Ferguson, Scott, Fischl, Bruce, Folkerth, Rebecca D, Gentleman, Steve, Giza, Christopher C, Grady, M Sean, Helmy, Adel, Herceg, Mark, Holton, Janice L, Howell, David, Hutchinson, Peter J, Iacono, Diego, Iglesias, Juan E, Ikonomovic, Milos D, Johnson, Victoria E, Keene, C Dirk ... Smith, Douglas H (2019). Primum non nocere: a call for balance when reporting on CTE. The Lancet Neurology, 18 (3), 231-233. doi: 10.1016/S1474-4422(19)30020-1
N-acetyl-aspartate in the dorsolateral prefrontal cortex long after concussion in youth
MacMaster, Frank P., McLellan, Quinn, Harris, Ashley D., Virani, Shane, Barlow, Karen M., Langevin, Lisa Marie, Yeates, Keith Owen and Brooks, Brian L. (2019). N-acetyl-aspartate in the dorsolateral prefrontal cortex long after concussion in youth. Journal of Head Trauma Rehabilitation, 35 (2), E127-E135. doi: 10.1097/HTR.0000000000000535
Natural Progression of Symptom Change and Recovery From Concussion in a Pediatric Population
Ledoux, Andree-Anne, Tang, Ken, Yeates, Keith O., Pusic, Martin, Boutis, Kathy, Craig, William R., Gravel, Jocelyn, Freedman, Stephen B., Gagnon, Isabelle, Gioia, Gerard A., Osmond, Martin H., Zemek, Roger L., for the Pediatric Emergency Research Canada (PERC) Concussion Team, McGahern, Candice, Sangha, Gurinder, Beer, Darcy, Burns, Emma, Farion, Ken J., Mikrogianakis, Angelo, Barlow, Karen, Dubrovsky, Alexander S., Meeuwisse, Willem, Meehan, William P., Kamil, Yael, Beauchamps, Miriam H., Hoshizaki, Blaine, Anderson, Peter, Brooks, Brian L., Vassilyadi, Michael ... DeMatteo, Carol (2019). Natural Progression of Symptom Change and Recovery From Concussion in a Pediatric Population. Jama Pediatrics, 173 (1). doi: 10.1001/jamapediatrics.2018.3820
Barlow, Karen, Esser, Michael M. J., Veidt, Myra and Boyd, Roslyn (2018). Melatonin as a treatment after traumatic brain injury: a systematic review and meta-analysis of the pre-clinical and clinical literature. Journal of Neurotrauma, 36 (4) neu.2018.5752, 523-537. doi: 10.1089/neu.2018.5752
No association between metoclopramide treatment in ED and reduced risk of post-concussion headache
Bresee, Natalie, Aglipay, Mary, Dubrovsky, Alexander Sasha, Ledoux, Andrée-Anne, Momoli, Franco, Gravel, Jocelyn, Freedman, Stephen B., Barlow, Karen, Richer, Lawrence, Barrowman, Nicholas J, Zemek, Roger and Pediatric Emergency Research Canada (PERC) 5P concussion team (2018). No association between metoclopramide treatment in ED and reduced risk of post-concussion headache. The American Journal of Emergency Medicine, 36 (12), 2225-2231. doi: 10.1016/j.ajem.2018.04.007
Determining if rest is best after concussion
Giza, Christopher C., Choe, Meeryo C. and Barlow, Karen M. (2018). Determining if rest is best after concussion. JAMA Neurology, 75 (4), 399-400. doi: 10.1001/jamaneurol.2018.0006
Pediatric Traumatic Brain Injury and Concussion
Choe, Meeryo and Barlow, Karen M. (2018). Pediatric Traumatic Brain Injury and Concussion. CONTINUUM Lifelong Learning in Neurology, 24 (1), 300-311. doi: 10.1212/CON.0000000000000569
Plourde, Vickie, Daya, Hussain, Low, Trevor A., Barlow, Karen M. and Brooks, Brian L. (2018). Evaluating anxiety and depression symptoms in children and adolescents with prior mild traumatic brain injury: Agreement between methods and respondents. Child Neuropsychology, 25 (1), 1-16. doi: 10.1080/09297049.2018.1432585
Cerebral blood flow in children and adolescents several years after concussion
Brooks, Brian L., Low, Trevor A., Plourde, Vickie, Virani, Shane, Jadavji, Zeanna, MacMaster, Frank P., Barlow, Karen M., Lebel, R. Marc and Yeates, Keith Owen (2018). Cerebral blood flow in children and adolescents several years after concussion. Brain Injury, 33 (2), 1-9. doi: 10.1080/02699052.2018.1540798
Cervicovestibular rehabilitation following sport-related concussion
Schneider, Kathryn J., Meeuwisse, Willem H., Barlow, Karen M. and Emery, Carolyn A. (2018). Cervicovestibular rehabilitation following sport-related concussion. British Journal of Sports Medicine, 52 (2), 100-101. doi: 10.1136/bjsports-2017-098667
Post, Andrew, Blaine Hoshizaki, T., Gilchrist, Michael D., Koncan, David, Dawson, Lauren, Chen, Wesley, Ledoux, Andrée-Anne, Zemek, Roger, McGahern, Candice, Sangha, Gurinder, Beer, Darcy, Craig, William, Farion, Ken J., Mikrogianakis, Angelo, Barlow, Karen, Dubrovsky, Alexander S., Meeuwisse, Willem, Meehan, William P., Kamil, Yael, Grool, Anne M., Hoshizaki, Blaine, Anderson, Peter, Brooks, Brian L., Vassilyadi, Michael, Klassen, Terry, Keightley, Michelle, Richer, Lawrence and DeMatteo, Carol (2018). Response. Journal of Neurosurgery: Pediatrics, 21 (1), 95-96. doi: 10.3171/2017.5.PEDS17231
Experts’ opinion about the pediatric secondary headaches diagnostic criteria of the ICHD-3 beta
Ozge, Aynur, Abu-Arafeh, Ishaq, Gelfand, Amy A., Goadsby, Peter James, Cuvellier, Jean Christophe, Valeriani, Massimiliano, Sergeev, Alexey, Barlow, Karen, Uluduz, Derya, Yalin, Osman Ozgur, Faedda, Noemi, Lipton, Richard B., Rapoport, Alan and Guidetti, Vincenzo (2017). Experts’ opinion about the pediatric secondary headaches diagnostic criteria of the ICHD-3 beta. Journal of Headache and Pain, 18 (1) 113. doi: 10.1186/s10194-017-0819-x
Ozge, Aynur, Faedda, Noemi, Abu-Arafeh, Ishaq, Gelfand, Amy A., Goadsby, Peter James, Cuvellier, Jean Christophe, Valeriani, Massimiliano, Sergeev, Alexey, Barlow, Karen, Uluduz, Derya, Yalin, Osman Ozgur, Lipton, Richard B., Rapoport, Alan and Guidetti, Vincenzo (2017). Experts’ opinion about the primary headache diagnostic criteria of the ICHD-3rd edition beta in children and adolescents. Journal of Headache and Pain, 18 (1) 109. doi: 10.1186/s10194-017-0818-y
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Maas, Andrew I. R., Menon, David K., Adelson, P. David, Andelic, Nada, Bell, Michael J., Belli, Antonio, Bragge, Peter, Brazinova, Alexandra, Büki, András, Chesnut, Randall M., Citerio, Giuseppe, Coburn, Mark, Cooper, D. Jamie, Crowder, A. Tamara, Czeiter, Endre, Czosnyka, Marek, Diaz-Arrastia, Ramon, Dreier, Jens P., Duhaime, Ann-Christine, Ercole, Ari, van Essen, Thomas A., Feigin, Valery L., Gao, Guoyi, Giacino, Joseph, Gonzalez-Lara, Laura E., Gruen, Russell L., Gupta, Deepak, Hartings, Jed A., Hill, Sean ... Barlow, Karen (2017). Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. The Lancet Neurology, 16 (12), 987-1048. doi: 10.1016/S1474-4422(17)30371-X
Yamakawa, Glenn R., Salberg, Sabrina, Barlow, Karen M., Brooks, Brian L., Esser, Michael J., Yeates, Keith Owen and Mychasiuk, Richelle (2017). Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology, gene expression, and response to melatonin treatment in rats. Experimental Neurology, 295, 55-65. doi: 10.1016/j.expneurol.2017.06.001
Yeates, Keith Owen, Beauchamp, Miriam, Craig, William, Doan, Quynh, Zemek, Roger, Bjornson, Bruce H., Gravel, Jocelyn, Mikrogianakis, Angelo, Goodyear, Bradley, Abdeen, Nishard, Beaulieu, Christian, Dehaes, Mathieu, Deschenes, Sylvain, Harris, Ashley, Lebel, Catherine, Lamont, Ryan, Williamson, Tyler, Barlow, Karen Maria, Bernier, Francois, Brooks, Brian L., Emery, Carolyn, Freedman, Stephen B., Kowalski, Kristina, Mrklas, Kelly, Tomfohr-Madsen, Lianne and Schneider, Kathryn J. (2017). Advancing Concussion Assessment in Pediatrics (A-CAP): A prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: Protocol study. BMJ Open, 7 (7) e017012, e017012. doi: 10.1136/bmjopen-2017-017012
Concussion rates and recovery in elite youth ice hockey players
Schneider, Kathryn J., Nettel-Aguirre, Alberto, Palacios-Derflingher, Luz, Mrazik, Martin, Brooks, Brian L., Woollings, Kaikanani, Blake, Tracy A., McKay, Carly D., Lebrun, Constance M., Barlow, Karen, Taylor, Kirsten A., Meeuwisse, Willem H. and Emery, Carolyn A. (2017). Concussion rates and recovery in elite youth ice hockey players. British Journal of Sports Medicine, 51 (11), A39-A40. doi: 10.1136/bjsports-2016-097270.101
Post, Andrew, Hoshizaki, T. Blaine, Gilchrist, Michael D., Koncan, David, Dawson, Lauren, Chen, Wesley, Ledoux, Andree-Anne, Zemek, Roger, The Pediatric Emergency Research Canada (PERC) 5P Concussion Team and Barlow, Karen (2017). A comparison in a youth population between those with and without a history of concussion using biomechanical reconstruction. Journal of Neurosurgery-Pediatrics, 19 (4), 502-510. doi: 10.3171/2016.10.PEDS16449
Cortical excitability after pediatric mild traumatic brain injury
Seeger, Trevor A., Kirton, Adam, Esser, Michael J., Gallagher, Clare, Dunn, Jeff, Zewdie, Ephrem, Damji, Omar, Ciechanski, Patrick and Barlow, Karen M. (2017). Cortical excitability after pediatric mild traumatic brain injury. Brain Stimulation, 10 (2), 305-314. doi: 10.1016/j.brs.2016.11.011
Validation of a Case Definition for Pediatric Brain Injury Using Administrative Data
McChesney-Corbeil, Jane, Barlow, Karen, Quan, Hude, Chen, Guanmin, Wiebe, Samuel and Jette, Nathalie (2017). Validation of a Case Definition for Pediatric Brain Injury Using Administrative Data. Canadian Journal of Neurological Sciences, 44 (2), 161-169. doi: 10.1017/cjn.2016.419
Grool, Anne M., Aglipay, Mary, Momoli, Franco, Meehan, William P., Freedman, Stephen B., Yeates, Keith Owen, Gravel, Jocelyn, Gagnon, Isabelle, Boutis, Kathy, Meeuwisse, Willem, Barrowman, Nick, Ledoux, Andrée-Anne, Osmond, Martin H., Zemek, Roger, Pediatric Emergency Research Canada (PERC) Concussion Team and Barlow, Karen (2016). Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents. JAMA, 316 (23), 2504-2514. doi: 10.1001/jama.2016.17396
Khetani, Aneesh M., Brooks, Brian L., Mikrogianakis, Angelo and Barlow, Karen M. (2016). Incorporating a computerized cognitive battery into the emergency department care of pediatric mild traumatic brain injuries—is it feasible?. Pediatric Emergency Care, 34 (7), 1-506. doi: 10.1097/pec.0000000000000959
Brooks, Brian L., Low, Trevor A., Daya, Hussain, Khan, Samna, Mikrogianakis, Angelo and Barlow, Karen M. (2016). Test or rest? Computerized cognitive testing in the emergency department after pediatric mild traumatic brain injury does not delay symptom recovery. Journal of Neurotrauma, 33 (23), 2091-2096. doi: 10.1089/neu.2015.4301
Hebert, Debbie, Lindsay, M. Patrice, McIntyre, Amanda, Kirton, Adam, Rumney, Peter G., Bagg, Stephen, Bayley, Mark, Dowlatshahi, Dar, Dukelow, Sean, Garnhum, Maridee, Glasser, Ev, Halabi, Mary-Lou, Kang, Ester, MacKay-Lyons, Marilyn, Martino, Rosemary, Rochette, Annie, Rowe, Sarah, Salbach, Nancy, Semenko, Brenda, Stack, Bridget, Swinton, Luchie, Weber, Valentine, Mayer, Matthew, Verrilli, Sue, DeVeber, Gabrielle, Andersen, John, Barlow, Karen, Cassidy, Caitlin, Dilenge, Marie-Emmanuelle ... Teasell, Robert (2016). Canadian stroke best practice recommendations: stroke rehabilitation practice guidelines, update 2015. International Journal of Stroke, 11 (4), 459-484. doi: 10.1177/1747493016643553
Brooks, Brian L., Daya, Hussain, Khan, Samna, Carlson, Helen L., Mikrogianakis, Angelo and Barlow, Karen M. (2016). Cognition in the emergency department as a predictor of recovery after pediatric mild traumatic brain injury. Journal of the International Neuropsychological Society, 22 (4), 379-387. doi: 10.1017/S1355617715001368
Zemek, Roger, Barrowman, Nick, Freedman, Stephen B., Gravel, Jocelyn, Gagnon, Isabelle, McGahern, Candice, Aglipay, Mary, Sangha, Gurinder, Boutis, Kathy, Beer, Darcy, Craig, William, Burns, Emma, Farion, Ken J., Mikrogianakis, Angelo, Barlow, Karen, Dubrovsky, Alexander S., Meeuwisse, Willem, Gioia, Gerard, Meehan, William P., Beauchamp, Miriam H., Kamil, Yael, Grool, Anne M., Hoshizaki, Blaine, Anderson, Peter, Brooks, Brian L., Yeates, Keith Owen, Vassilyadi, Michael, Klassen, Terry, Keightley, Michelle ... Osmond, Martin H. (2016). Clinical risk score for persistent postconcussion symptoms among children with acute concussion in the ED. JAMA-Journal of the American Medical Association, 315 (10), 1014-1025. doi: 10.1001/jama.2016.1203
Emery, Carolyn A., Barlow, Karen M., Brooks, Brian L., Max, Jeffrey E., Villavicencio-Requis, Angela, Gnanakumar, Vithya, Robertson, Helen Lee, Schneider, Kathryn and Yeates, Keith Owen (2016). A systematic review of psychiatric, psychological, and behavioural outcomes following mild traumatic brain injury in children and adolescents. Canadian Journal of Psychiatry, 61 (5), 259-269. doi: 10.1177/0706743716643741
Occipital Nerve Blocks for Pediatric Posttraumatic Headache: A Case Series
Seeger, Trevor A., Orr, Serena, Bodell, Lisa, Lockyer, Lisette, Rajapakse, Thilinie and Barlow, Karen M. (2015). Occipital Nerve Blocks for Pediatric Posttraumatic Headache: A Case Series. Journal of Child Neurology, 30 (9), 1142-1146. doi: 10.1177/0883073814553973
QTc Prolongation in Acute Pediatric Migraine
May, Lindsay J., Millar, Kelly, Barlow, Karen M. and Dicke, Frank (2015). QTc Prolongation in Acute Pediatric Migraine. Pediatric Emergency Care, 31 (6), 409-411. doi: 10.1097/PEC.0000000000000250
Urban, Karolina J., Barlow, Karen M., Jimenez, Jon J., Goodyear, Bradley G. and Dunn, Jeff F. (2015). Functional near-infrared spectroscopy reveals reduced interhemispheric cortical communication after pediatric concussion. Journal of Neurotrauma, 32 (11), 833-840. doi: 10.1089/neu.2014.3577
Barlow, Karen M., Crawford, Susan, Brooks, Brian L., Turley, Brenda and Mikrogianakis, Angelo (2015). The Incidence of Postconcussion Syndrome Remains Stable Following Mild Traumatic Brain Injury in Children. Pediatric Neurology, 53 (6), 491-497. doi: 10.1016/j.pediatrneurol.2015.04.011
Postconcussion syndrome: A review
Barlow, Karen M. (2014). Postconcussion syndrome: A review. Journal of Child Neurology, 31 (1), 57-67. doi: 10.1177/0883073814543305
Neurocognition in the emergency department after a mild traumatic brain injury in youth
Brooks, Brian L., Khan, Samna, Daya, Hussain, Mikrogianakis, Angelo and Barlow, Karen M. (2014). Neurocognition in the emergency department after a mild traumatic brain injury in youth. Journal of Neurotrauma, 31 (20), 1744-1749. doi: 10.1089/neu.2014.3356
Barlow, Karen M., Brooks, Brian L., MacMaster, Frank P., Kirton, Adam, Seeger, Trevor, Esser, Michael, Crawford, Susan, Nettel-Aguirre, Alberto, Zemek, Roger, Angelo, Mikrogianakis, Kirk, Valerie, Emery, Carolyn A., Johnson, David, Hill, Michael D., Buchhalter, Jeff, Turley, Brenda, Richer, Lawrence, Platt, Robert, Hutchison, Jamie and Dewey, Deborah (2014). A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): Study protocol for a randomized controlled trial. Trials, 15 (1) 271. doi: 10.1186/1745-6215-15-271
Cervicovestibular rehabilitation in sport-related concussion: a randomised controlled trial
Schneider, Kathryn J., Meeuwisse, Willem H., Nettel-Aguirre, Alberto, Barlow, Karen, Boyd, Lara, Kang, Jian and Emery, Carolyn A. (2014). Cervicovestibular rehabilitation in sport-related concussion: a randomised controlled trial. British Journal of Sports Medicine, 48 (17), 1294-1298. doi: 10.1136/bjsports-2013-093267
Absence of differences between male and female adolescents with prior sport concussion
Brooks, Brian L., Mrazik, Martin, Barlow, Karen M., McKay, Carly D., Meeuwisse, Willem H. and Emery, Carolyn A. (2014). Absence of differences between male and female adolescents with prior sport concussion. Journal of Head Trauma Rehabilitation, 29 (3), 257-264. doi: 10.1097/HTR.0000000000000016
Taylor, K., Brooks, B.L., Schneider, K.J., Blake, T.A., McKay, C.D., Meeuwisse, W.H., Barlow, K.M., Kang, J. and Emery, C.A. (2014). Neurocognitive performance at return to play in elite youth hockey players with sport-related concussion. British Journal of Sports Medicine, 48 (7), 664-664. doi: 10.1136/bjsports-2014-093494.278
Brooks, Brian L., Kadoura, Basil, Turley, Brenda, Crawford, Susan, Mikrogianakis, Angelo and Barlow, Karen M. (2014). Perception of recovery after pediatric mild traumatic brain injury is influenced by the "good old days" bias: tangible implications for clinical practice and outcomes research. Archives of Clinical Neuropsychology, 29 (2), 186-193. doi: 10.1093/arclin/act083
Smyth, Kim, Sandhu, Sandeep S., Crawford, Susan, Dewey, Deborah, Parboosingh, Jillian and Barlow, Karen M. (2014). The role of serotonin receptor alleles and environmental stressors in the development of post-concussive symptoms after pediatric mild traumatic brain injury. Developmental Medicine and Child Neurology, 56 (1), 73-77. doi: 10.1111/dmcn.12263
Subjective, but not objective, lingering effects of multiple past concussions in adolescents
Brooks, Brian L., McKay, Carly D., Mrazik, Martin, Barlow, Karen M., Meeuwisse, Willem H. and Emery, Carolyn A. (2013). Subjective, but not objective, lingering effects of multiple past concussions in adolescents. Journal of Neurotrauma, 30 (17), 1469-1475. doi: 10.1089/neu.2012.2720
Zemek, Roger, Osmond, Martin H., Barrowman, Nick, Pediatric Emergency Research Canada (PERC) Concussion Team and Barlow, Karen (2013). Predicting and preventing postconcussive problems in paediatrics (5P) study: protocol for a prospective multicentre clinical prediction rule derivation study in children with concussion. BMJ Open, 3 (8). doi: 10.1136/bmjopen-2013-003550
Kuczynski, Andrea, Crawford, Susan, Bodell, Lisa, Dewey, Deborah and Barlow, Karen M. (2013). Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort. Developmental Medicine and Child Neurology, 55 (7), 636-641. doi: 10.1111/dmcn.12152
Linkage between neurological registry data and administrative data
Jette, Nathalie, Atwood, Kristin, Hamilton, Mark, Hayward, Rachel, Day, Lundy, Mobach, Theo, Maxwell, Colleen, Fortin, Claire Marie, Fiebelkorn, Guillermo, Barlow, Karen, Shevell, Michael, Kapral, Moira K., Casha, Steve, Johnston, Megan, Wiebe, Samuel, Korngut, Lawrence and Pringsheim, Tamara (2013). Linkage between neurological registry data and administrative data. Canadian Journal of Neurological Sciences, 40 (4), S32-S34. doi: 10.1017/S0317167100017145
Patient Recruitment by Neurological Registries
Hamilton, Mark, Genge, Angela, Johnston, Megan, Lam, Darren, Mobach, Theo, Marriott, James, Steeves, Thomas, Donner, Elizabeth, Wysocki, Julie, Barlow, Karen, Shevell, Michael, Marrie, Ruth Ann, Casha, Steve, MacKean, Gail, Casselman, Lisa, Korngut, Lawrence, Pringsheim, Tamara and Jette, Nathalie (2013). Patient Recruitment by Neurological Registries. Canadian Journal of Neurological Sciences, 40 (4), S23-S26. doi: 10.1017/S0317167100017121
Validation and interpretation of neurological registry data
Pringsheim, Tamara, Lam, Darren, Day, Lundy, Genge, Angela, Hogan, David, Shevell, Michael, Fortin, Claire, Maxwell, Colleen, Fiebelkorn, Guillermo, Barlow, Karen, Kapral, Moira, Casha, Steve, Mobach, Theo, Johnston, Megan, Jette, Nathalie and Korngut, Lawrence (2013). Validation and interpretation of neurological registry data. Canadian Journal of Neurological Sciences, 40 (S2), S51-S53. doi: 10.1017/S0317167100017182
Barlow, Karen Maria (2013). Traumatic brain injury. Handbook of Clinical Neurology, 112, 891-904. doi: 10.1016/B978-0-444-52910-7.00011-8
Weight gain after childhood traumatic brain injury
Barlow, Karen (2012). Weight gain after childhood traumatic brain injury. Developmental Medicine and Child Neurology, 54 (7), 583-583. doi: 10.1111/j.1469-8749.2012.04303.x
Sarnat, Harvey B., Wei, Xing-Chang, Flores-Sarnat, Laura, Trevenen, Cynthia L. and Barlow, Karen (2012). Fetal opercular cavernous angioma causing cerebral cleft: contralateral primitive vascular anomaly and subicular dysgenesis. Journal of Child Neurology, 27 (4), 478-484. doi: 10.1177/0883073811420293
Brooks, Brian L. and Barlow, Karen M. (2011). A methodology for assessing treatment response in Hashimoto's encephalopathy: a case study demonstrating repeated computerized neuropsychological testing. Journal of Child Neurology, 26 (6), 786-791. doi: 10.1177/0883073810391532
Smith, Sabrina E., Kirkham, Fenella J., Deveber, Gabrielle, Millman, Guy, Dirks, Peter B., Wirrell, Elaine, Telfeian, Albert E., Sykes, Kim, Barlow, Karen and Ichord, Rebecca (2011). Outcome following decompressive craniectomy for malignant middle cerebral artery infarction in children. Developmental Medicine and Child Neurology, 53 (1), 29-33. doi: 10.1111/j.1469-8749.2010.03775.x
Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury
Barlow, Karen Maria, Crawford, Susan, Stevenson, Andrea, Sandhu, Sandeep Sona, Belanger, Francois and Dewey, Deborah (2010). Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury. Pediatrics, 126 (2), E374-E381. doi: 10.1542/peds.2009-0925
Intracranial pressure measurement in children
Barlow, Karen M. (2007). Intracranial pressure measurement in children. Developmental Medicine and Child Neurology, 49 (12), 886-886. doi: 10.1111/j.1469-8749.2007.00886.x
Neurorehabilitation of children with cerebral palsy
Maria Barlow, Karen (2007). Neurorehabilitation of children with cerebral palsy. Handbook of Clinical Neurology, 87, 591-609. doi: 10.1016/S0072-9752(07)87032-1
Sleep disturbances in children with epilepsy compared with their nearest-aged siblings
Wirrell, E, Blackman, M, Barlow, K, Mah, J and Hamiwka, L (2005). Sleep disturbances in children with epilepsy compared with their nearest-aged siblings. Developmental Medicine and Child Neurology, 47 (11), 754-759. doi: 10.1017/S0012162205001581
Use of complementary and alternative medical therapies in a pediatric neurology clinic
Soo, Isaac, Mah, Jean K., Barlow, Karen, Hamiwka, Lorie and Wirrell, Elaine (2005). Use of complementary and alternative medical therapies in a pediatric neurology clinic. Canadian Journal of Neurological Sciences, 32 (4), 524-528. doi: 10.1017/S0317167100004558
Autosomal recessive cerebellar hypoplasia in the Hutterite population
Glass, H. C., Boycott, K. M., Adams, C., Barlow, K., Scott, J. N., Chudley, A. E., Fujiwara, T. M., Morgan, K., Wirrell, E. and McLeod, D. R. (2005). Autosomal recessive cerebellar hypoplasia in the Hutterite population. Developmental Medicine and Child Neurology, 47 (10), 691-695. doi: 10.1017/S0012162205001404
Late neurologic and cognitive sequelae of inflicted traumatic brain injury in infancy
Barlow, Karen M., Thomson, Elaine, Johnson, David and Minns, Robert A. (2005). Late neurologic and cognitive sequelae of inflicted traumatic brain injury in infancy. Pediatrics, 116 (2), E174-E185. doi: 10.1542/peds.2004-2739
Stroke after varicella vaccination
Wirrell, E, Hill, MD, Jadavji, T, Kirton, A and Barlow, K (2004). Stroke after varicella vaccination. Journal of Pediatrics, 145 (6), 845-847. doi: 10.1016/j.jpeds.2004.08.005
The neurological outcome of non-accidental head injury
Barlow, Karen, Thompson, Elaine, Johnson, David and Minns, Robert A. (2004). The neurological outcome of non-accidental head injury. Pediatric Rehabilitation, 7 (3), 195-203. doi: 10.1080/13638490410001715331
Annual incidence of shaken impact syndrome in young children
Barlow, KM and Minns, RA (2000). Annual incidence of shaken impact syndrome in young children. Lancet, 356 (9241), 1571-1572. doi: 10.1016/S0140-6736(00)03130-5
Early posttraumatic seizures in non-accidental head injury: relation to outcome
Barlow, Karen M., Spowart, Jacqui J. and Minns, Robert A. (2000). Early posttraumatic seizures in non-accidental head injury: relation to outcome. Developmental Medicine and Child Neurology, 42 (9), 591-594. doi: 10.1111/j.1469-8749.2000.tb00363.x
Magnetic resonance imaging in acute non-accidental head injury
Barlow, K. M., Gibson, R. J., McPhillips, M. and Minns, R. A. (1999). Magnetic resonance imaging in acute non-accidental head injury. Acta Paediatrica, International Journal of Paediatrics, 88 (7), 734-740. doi: 10.1080/08035259950169017
The relation between intracranial pressure and outcome in non-accidental head injury
Barlow, Karen M. and Minns, Robert A. (1999). The relation between intracranial pressure and outcome in non-accidental head injury. Developmental Medicine and Child Neurology, 41 (4) S0012162299000481, 220-225. doi: 10.1111/j.1469-8749.1999.tb00588.x
Neurological and neuropsychological outcome of non-accidental head injury
Barlow, K. M., Thomson, E. and Minns, R. A. (1999). Neurological and neuropsychological outcome of non-accidental head injury. European Journal of Paediatric Neurology, 3 (6), A139-A140. doi: 10.1016/s1090-3798(99)91352-1
Barlow, K. M., Milne, S., Aitken, K. and Minns, R. A. (1998). A Retrospective Epidemiological Analysis of Non-Accidental Head Injury in Children in Scotland over a 15 Year Period. Scottish Medical Journal, 43 (4), 112-114. doi: 10.1177/003693309804300407
Dizygotic Twins Discordant for Hiv and Hepatitis-C Virus
Barlow, KM and Mok, Jyq (1993). Dizygotic Twins Discordant for Hiv and Hepatitis-C Virus. Archives of Disease in Childhood, 68 (4), 507-507. doi: 10.1136/adc.68.4.507
Dizygotic twins discordant for HIV and hepatitis C virus
Barlow, Karen M. and Mok, Jacqueline Y. Q. (1993). Dizygotic twins discordant for HIV and hepatitis C virus. Archives of Disease in Childhood, 68 (4), 507-507. doi: 10.1136/adc.68.4.507
Bonthron, D. T., Barlow, K. M., Burt, A. M. and Barr, D. G. (1993). Parental consanguinity in the blepharophimosis, heart defect, hypothyroidism, mental retardation syndrome (Young-Simpson syndrome). Journal of Medical Genetics, 30 (3), 255-256. doi: 10.1136/jmg.30.3.255
Samuel, Tina, Lockyer, Lisette, Turley, Brenda, Bodell, Lisa, Yeates, Keith and Barlow, Karen (2017). Curious about concussions: An evaluation of an education session about concussion and mild traumatic brain injuries management. TAYLOR & FRANCIS INC.
Plourde, V., Low, T., Jadavji, Z., Virani, S., Barlow, K., Yeates, K. and Brooks, B. (2017). Do Pre-existing Psychological or Neurodevelopmental Problems Predict Long-term Functioning in Children and Adolescents with Prior Concussions?. OXFORD UNIV PRESS. doi: 10.1093/arclin/acx076.149
Khetani, Aneesh, Hu, Sophie, MacMaster, Frank P., Bray, Signe and Barlow, Karen (2017). Evaluation of a visuo-spatial n-back task in FMRI to examine working memory network activation in children following a mild traumatic brain injury. TAYLOR & FRANCIS INC.
Godfrey, Heather, Samuel, Tina and Barlow, Karen (2017). Improving paediatric concussion care through knowledge translation and confidence building in paediatric emergency room nurses. unknown, unknown, unknown. TAYLOR & FRANCIS INC.
Longitudinal follow-up of cortical excitability in paediatric traumatic brain injury
King, Regan, Seeger, Trevor, Zewdie, Ephrem, Ciechanski, Patrick, Damji, Omar, Kirton, Adam, Barlow, Karen and Nettel-Aguirre, Alberto (2017). Longitudinal follow-up of cortical excitability in paediatric traumatic brain injury. TAYLOR & FRANCIS INC.
Yan, Tingting, Carlson, Helen, Lebel, Marc, Beutle, Alexander, Khetani, Aneesh and Barlow, Karen (2017). Quantifying cerebral perfusion changes over time during recovery from a mild traumatic brain injury in children. TAYLOR & FRANCIS INC.
Watch me go: Activity in children following concussion and its association with outcome
Park, Sarah (Suhyeon), Goldstein, Genevieve, Ofoghi, Zahra and Barlow, Karen (2017). Watch me go: Activity in children following concussion and its association with outcome. TAYLOR & FRANCIS INC.
Barlow, K. M., Marcil, L. D., Dewey, D., Carlson, H., MacMaster, F. P., Brooks, B. L. and Lebel, R. M. (2016). A.03 Cerebral perfusion and its relationship to post-concussion syndrome in mild traumatic brain injury: a prospective controlled cohort study. Canadian Neurological Sciences Federation 51st Congress, Quebec City, Canada, 21-24 June 2016. New York, NY United States: Cambridge University Press. doi: 10.1017/cjn.2016.55
Barlow, Karen, Lorenzo, Marcil, Calson, Helen and Marc, Lebel (2016). Cerebral Perfusion Changes in Children with and without Post-Concussion Syndrome Following a Mild Traumatic Brain Injury Using Arterial Spin Labelling. 68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver Canada, 15-21 April 2016. Philadelphia, PA United States: Lippincott Williams & Williams.
Barlow, Karen, Lorenzo, Marcil, Calson, Helen and Marc, Lebel (2016). Cerebral Perfusion Changes in Children with and without Post-Concussion Syndrome Following a Mild Traumatic Brain Injury Using Arterial Spin Labelling. 68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver Canada, Apr 15-21, 2016. LIPPINCOTT WILLIAMS & WILKINS.
Barlow, Karen, Lorenzo, Marcil, Calson, Helen and Marc, Lebel (2016). Cerebral Perfusion Changes in Children with and without Post-Concussion Syndrome Following a Mild Traumatic Brain Injury Using Arterial Spin Labelling. 68th Annual Meeting of the American Academy of Neurology (AAN), Vancouver, BC, Canada, 15-21 April 2016. Philadelphia, PA, United States: Lippincott Williams & Wilkins.
Clinical risk score for persistent post-concussion symptoms in paediatrics
Zemek, Roger, Barrowman, Nick, Freedman, Stephen B., Gravel, Jocelyn, Gagnon, Isabelle, McGahern, Candice, Aglipay, Mary, Sangha, Gurinder, Boutis, Kathy, Beer, Darcy, Craig, William, Burns, Emma, Farion, Ken J., Mikrogianakis, Angelo, Barlow, Karen, Dubrovsky, Alexander S., Meeuwisse, Willem, Gioia, Gerard and Osmond, Martin (2016). Clinical risk score for persistent post-concussion symptoms in paediatrics. TAYLOR & FRANCIS INC.
Cortical Excitability After Mild Traumatic Brain Injury in Children
Seeger, Trevor, Kirton, Adam and Barlow, Karen (2016). Cortical Excitability After Mild Traumatic Brain Injury in Children. 68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver, Canada, 15-21 April 2016. LIPPINCOTT WILLIAMS & WILKINS.
Dunn, J. F., Urban, K. J., Goodyear, B. G. and Barlow, K. M. (2016). Using Functional Near-Infrared Spectroscopy to Map Reduced Inter-Hemispheric Connectivity in Pediatric Concussion Patients. 27th International Symposium on Cerebral Blood Flow, Metabolism and Function / 12th International Conference on Quantification of Brain Function with PET, Vancouver Canada, Jun 27-30, 2015. SAGE PUBLICATIONS INC.
The influence of pre-injury headaches on outcome following concussion in children
Barlow, K., Crawford, S., Turley, B. and Mikrogianakis, A. (2015). The influence of pre-injury headaches on outcome following concussion in children. International Headache Congress of the International-Headache-Society, Valencia, Spain, 14-17 May 2015. London, United Kingdom: Sage Publications.
Barlow, K. M., Dewey, D., Urban, K. J., Seeger, T., Kirton, A., MacMaster, F., Brooks, B., Mikrogianakis, A., Crawford, S., Netel-Aguirre, A., Johnson, D., Kirk, V., Zemek, R. and Buchhalter, J. (2014). PLAYGAME: A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL OF MELATONIN FOR THE TREATMENT OF POST CONCUSSION SYNDROME IN YOUTH. 32nd Annual National Neurotrauma Symposium, San Francisco Ca, Jun 29-Jul 02, 2014. NEW ROCHELLE: MARY ANN LIEBERT, INC.
Schneider, Kathryn, Meeuwisse, Willem, Nettel-Aguirre, Alberto, Barlow, Karen, Boyd, Lara, Kang, Jian and Emery, Carolyn (2014). Cervico-vestibular physiotherapy in the treatment of individuals with persistent symptoms following sport-related concussion: A randomized controlled trial. LONDON: INFORMA HEALTHCARE.
Response to occipital nerve block after traumatic brain injury in adolescents
Seeger, Trevor, Bodell, Lisa, Rajapakse, Thilinie, Lockyer, Lisette, Esser, Michael and Barlow, Karen (2014). Response to occipital nerve block after traumatic brain injury in adolescents. LONDON: INFORMA HEALTHCARE.
The feasibility of computerized cognitive testing in the paediatric emergency room
Khetani, Aneesh, Khan, Annie, Kadoura, Basil, Narous, Mariam, Brooks, Brian and Barlow, Karen Maria (2014). The feasibility of computerized cognitive testing in the paediatric emergency room. LONDON: INFORMA HEALTHCARE.
Urban, K. J., Barlow, K. M., Jimenez, J. J., Goodyear, B. G. and Dunn, J. F. (2014). Pediatric Post-Concussion Symptoms Are Associated with Reduced Cortical Communication as Detected with Near-Infrared Spectroscopy. 32nd Annual National Neurotrauma Symposium, San Francisco Ca, Jun 29-Jul 02, 2014. MARY ANN LIEBERT, INC.
Hong, Taeyoung Peter, Scurfield, Alex, Schneider, Kathryn, Narous, Mariam, Esser, Michael and Barlow, Karen Maria (2014). Vestibular dysfunction following paediatric traumatic brain injury-Prevalence and exploration of a novel diagnostic tool. INFORMA HEALTHCARE.
The "Good Old Days" Bias in Pediatric Mild Traumatic Brain Injury
Kadoura, Basil, Brian, Brooks, Crawford, Susan, Mikrogianakis, Angelo and Barlow, Karen (2013). The "Good Old Days" Bias in Pediatric Mild Traumatic Brain Injury. 65th Annual Meeting of the American-Academy-of-Neurology (AAN), San Diego Ca, Mar 16-23, 2013. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Barlow, Karen Maria, Kuczynski, Andrea, Crawford, Susan and Bodell, Lisa (2012). The characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment. LONDON: INFORMA HEALTHCARE.
Exploring the "good old days" bias in pediatric mild traumatic brain injury
Barlow, Karen Maria, Kadoura, Basil and Brooks, Brian (2012). Exploring the "good old days" bias in pediatric mild traumatic brain injury. unknown, unknown, unknown. INFORMA HEALTHCARE.
Predicting the outcome of mild traumatic brain injury in children
Barlow, Karen, Crawford, Susan and Dewie, Deborah (2012). Predicting the outcome of mild traumatic brain injury in children. The International Brain Injury Association's Ninth World Congress on Brain Injury, Edinburgh, United Kingdom, 21-25 March 2012. Abingdon, Oxfordshire, United Kingdom: Taylor & Francis. doi: 10.3109/02699052.2012.660091
Exploring the "good old days" Bias in Paediatric Mild Traumatic Brain Injury
Kadoura, Basil, Brooks, Brian, Crawford, Susan and Barlow, Karen (2011). Exploring the "good old days" Bias in Paediatric Mild Traumatic Brain Injury. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Executive Functioning, DTI, and Cortical Thickness in Pediatric Epilepsy
Sherman, E., Carlson, H., Gaxiola-Valdez,, Wei, X., Beaulieu, C., Hader, W., Brooks, B., Kirton, A., Barlow, K., Hrabok, M., Mohamed, and Wiebe, S. (2011). Executive Functioning, DTI, and Cortical Thickness in Pediatric Epilepsy. 31st Annual Meeting of the National Academy of Neuropsychology, Marco Island, FL, United States, 16-19 November 2011. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/arclin/acr052
Brooks, B., Fay, T. and Barlow, K. (2010). Hashimoto's encephalopathy: a pediatric case study with pre- and post-treatment neuropsychological testing. Archives of Clinical Neuropsychology 2010 Annual Meeting Abstracts, Unknown, 2010. Oxford, United Kingdom: Oxford University Press.
Predicting post-concussion syndrome at three months after a mild traumatic head injury in children
Barlow, Karen Maria, Crawford, Susan, Sandhu, Sona and Dewey, Deborah (2009). Predicting post-concussion syndrome at three months after a mild traumatic head injury in children. 2nd Joint Symposium of the National-and-International-Neurotrauma-Societies, Santa Barbara, CA, United States, 7-11 September 2009. New Rochelle, NY, United States: Mary Ann Liebert.
Chronic daily headache in children attending a tertiary referral headache clinic
Kohut, Elizabeth, Vaz, Jason A. and Barlow, Karen Maria (2008). Chronic daily headache in children attending a tertiary referral headache clinic. 7th International Congress on Headache in Children and Adolescents, Istanbul Turkey, 17-21 May 2008. London, United Kingdom: Sage.
Vaz, J., Kohut, E., Mah, J. and Barlow, K. M. (2007). A large retrospective study examining the clinical features of children seen by a neurology service in a tertiary referral centre. 36th Annual Meeting of the Child-Neurology-Society, Quebec City, QC, Canada, 10-13 October 2007. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ana.11636
Barlow, K. M., Stevenson, A. S., Latter, J., Hage, B., Crawford, S., Nettel-Aguirre, A. and Dewey, D. (2007). The epidemiology of post-concussion syndrome in children following traumatic brain injury: A preliminary report. 36th Annual Meeting of the Child-Neurology-Society, Quebec City Canada, Oct 10-13, 2007. HOBOKEN: WILEY-LISS.
A study of rehabilitative services utilization among pediatric neurosciences patients
Lee, C, Mah, J and Barlow, K (2005). A study of rehabilitative services utilization among pediatric neurosciences patients. 34th Annual Meeting of the Child-Neurology-Society, Los Angeles Ca, Sep 28-Oct 01, 2005. HOBOKEN: WILEY-LISS.
Dysequilibrium syndrome in Hutterites: Autosomal-recessive cerebellar hypoplasia
Glass, HC, Boycott, KM, Adams, C, Barlow, K, Scott, J, Morgan, K, Fujiwara, M, Wirrell, E and McLeod, DR (2004). Dysequilibrium syndrome in Hutterites: Autosomal-recessive cerebellar hypoplasia. 33rd Annual Meeting of the Child-Neurology-Society, Toronto Canada, Oct 13-16, 2004. HOBOKEN: WILEY-LISS.
Sleep disturbances in children with epilepsy compared with their nearest-aged siblings
Wirrell, E. C., Hamiwka, L. D., Blackman, M. A., Mah, J. K., Barlow, K. M. and Brisbane, J. (2004). Sleep disturbances in children with epilepsy compared with their nearest-aged siblings. Annual Meeting of the American-Epilepsy-Society, New Orlands La, 03-07 December 2004. Hoboken, NJ United States: Wiley-Blackwell Publishing.
The prognostic significance of early post-traumatic seizures in non-accidental head injury
Barlow, K. M., Spowart, J. J. and Minns, R. A. (1999). The prognostic significance of early post-traumatic seizures in non-accidental head injury. New York, United States: Nature Publishing Group. doi: 10.1203/00006450-199906000-00132
The relationship between intracranial pressure and outcome in nonaccidental head injury
Barlow, KM and Minns, RA (1998). The relationship between intracranial pressure and outcome in nonaccidental head injury. LIPPINCOTT WILLIAMS & WILKINS.
Melatonin as a therapeutic agent for post-concussion syndrome after mild traumatic brain injury
Barlow, Karen (2020). Melatonin as a therapeutic agent for post-concussion syndrome after mild traumatic brain injury. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2020.851
(2022–2026) Murdoch Childrens Research Institute
(2022–2025) Curtin University
(2022–2024) NHMRC MRFF Traumatic Brain Injury Mission
(2020–2024) Deakin University
(2019–2023) Motor Accident Insurance Commission
Healthcare utilisation after childhood traumatic brain injury in Queensland
(2019–2022) Motor Accident Insurance Commission
Health care utilization after childhood acquired brain injury in Queensland: A cost-of-illness study
(2019–2021) The Children's Hospital Foundation
(2018–2021) Financial Markets Foundation for Children
(2018–2019) Ian Potter Foundation
(2018) UQ Major Equipment and Infrastructure
(2018) The Children's Hospital Foundation
Helping children to flourish by improving sleep after childhood traumatic brain injury
Doctor Philosophy — Principal Advisor
Other advisors:
Using Non-Invasive Brain Stimulation to "Rewire" the Brain After Childhood Brain Injury
Doctor Philosophy — Principal Advisor
Other advisors:
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.
Exploring neuromodulation therapies for post concussive symptoms in children
Using mulitmodal neuroimaging to explore the neurobiology of post-concussion syndrome in children
Clinical care pathways following concussion - using technology to guide the way
Health service utilization after traumatic brain injury in children: what do they need and how can we help?