The University of Queensland

Macrophage heterogeneity in the single cell era: facts and artefacts

Hume, David A, Millard, Susan M and Pettit, Allison R. (2023). Macrophage heterogeneity in the single cell era: facts and artefacts. Blood Journal. doi: 10.1182/blood.2023020597

3152 – HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION

Millard, Susan, Kaur, Simranpreet, Choo, Fang Ming and Pettit, Allison (2023). 3152 – HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION. Experimental Hematology, 124, S125. doi: 10.1016/j.exphem.2023.06.259

Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

Tseng, Hsu‐Wen, Kulina, Irina, Girard, Dorothée, Gueguen, Jules, Vaquette, Cedryck, Salga, Marjorie, Fleming, Whitney, Jose, Beulah, Millard, Susan M., Pettit, Allison R., Schroder, Kate, Thomas, Gethin, Wheeler, Lawrie, Genêt, François, Banzet, Sébastien, Alexander, Kylie A. and Levesque, Jean‐Pierre (2022). Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification. Journal of Bone and Mineral Research, 37 (3), 531-546. doi: 10.1002/jbmr.4482

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Tseng, Hsu-Wen, Girard, Dorothée, Alexander, Kylie A., Millard, Susan M., Torossian, Frédéric, Anginot, Adrienne, Fleming, Whitney, Gueguen, Jules, Goriot, Marie-Emmanuelle, Clay, Denis, Jose, Beulah, Nowlan, Bianca, Pettit, Allison R., Salga, Marjorie, Genêt, François, Bousse-Kerdilès, Marie-Caroline Le, Banzet, Sébastien and Lévesque, Jean-Pierre (2022). Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Research, 10 (1) 22, 22. doi: 10.1038/s41413-022-00188-y

1015 – APPEARANCES CAN BE DECEIVING: MACROPHAGE FRAGMENTATION CONFOUNDS EX VIVO HAEMATOPOIETIC TISSUE ANALYSIS

Pettit, Allison R, Batoon, Lena, Heng, Ostyn, Hume, David, Irvine, Kate, Kaur, Simranpreet, Levesque, Jean-Pierre, Magor, Graham, Millard, Susan, Noll, Jacqueline, Perkins, Andrew, Raggatt, Liza, Sandrock, Cheyenne, Sehgal, Anuj, Sester, David, Opperman, Khatora Shanae, Summers, Kim, Wu, Andy and Zannettino, Andrew (2022). 1015 – APPEARANCES CAN BE DECEIVING: MACROPHAGE FRAGMENTATION CONFOUNDS EX VIVO HAEMATOPOIETIC TISSUE ANALYSIS. Experimental Hematology, 111, S23. doi: 10.1016/j.exphem.2022.07.018

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

Millard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058

Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation

Lévesque, Jean-Pierre, Summers, Kim M., Bisht, Kavita, Millard, Susan M., Winkler, Ingrid G. and Pettit, Allison R. (2021). Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation. Experimental Hematology, 103, 1-14. doi: 10.1016/j.exphem.2021.08.011

Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Wu, Andy C., Kaur, Simranpreet, Sun, Lucas W.H., Williams, Kyle, Sandrock, Cheyenne, Ng, Pei Ying, Irvine, Katharine M., Bartnikowski, Michal, Glatt, Vaida, Pavlos, Nathan J. and Pettit, Allison R. (2021). Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. Journal of Bone and Mineral Research, 36 (11), 2214-2228. doi: 10.1002/jbmr.4413

Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches

Lévesque, Jean-Pierre, Summers, Kim M., Millard, Susan, Bisht, Kavita, Winkler, Ingrid G. and Pettit, Allison R. (2021). Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches. Experimental Hematology, 100, 12-31. doi: 10.1016/j.exphem.2021.07.001

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936, 120936. doi: 10.1016/j.biomaterials.2021.120936

Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells

Lukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402

Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1

Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

Tay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

Alexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033

Osteomacs and bone regeneration

Batoon, Lena, Millard, Susan Marie, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). Osteomacs and bone regeneration. Current Osteoporosis Reports, 15 (4), 385-395. doi: 10.1007/s11914-017-0384-x

Role of osteoblast Gi signaling in age-related bone loss in female mice

Millard, Susan M., Wang, Liping, Wattanachanya, Lalita, O'Carroll, Dylan, Fields, Aaron J., Pang, Joyce, Kazakia, Galateia, Lotz, Jeffrey C. and Nissenson, Robert A. (2017). Role of osteoblast Gi signaling in age-related bone loss in female mice. Endocrinology, 158 (6), 1715-1726. doi: 10.1210/en.2016-1365

Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells

Karpova, Darja, Ritchey, Julie K., Holt, Matthew S., Abou-Ezzi, Grazia, Monlish, Darlene, Batoon, Lena, Millard, Susan, Spohn, Gabriele, Wiercinska, Eliza, Chendamarai, Ezhil, Yang, Wei, Christ, Stephanie, Gehrs, Leah, Schuettpelz, Laura G., Dembowsky, Klaus, Pettit, Allison R., Rettig, Michael P., Bonig, Halvard and DiPersio, John F. (2017). Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. Blood, 129 (21), 2939-2949. doi: 10.1182/blood-2016-10-746909

Gs/Gi regulation of bone cell differentiation: review and insights from engineered receptors

Hsiao, E. C., Millard, S. M. and Nissenson, R. A. (2016). Gs/Gi regulation of bone cell differentiation: review and insights from engineered receptors. Hormone and Metabolic Research, 48 (11), 689-699. doi: 10.1055/s-0042-116156

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

Alexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74

Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts

Millard, Susan M., Pettit, Allison R., Ellis, Rebecca, Chan, Jerry K. Y., Raggatt, Liza J., Khosrotehrani, Kiarash and Fisk, Nicholas M. (2015). Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts. Stem Cell Reports, 5 (5), 682-689. doi: 10.1016/j.stemcr.2015.09.017

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle

Genet, Francois, Kulina, Irina, Vaquette, Cedryck, Torossian, Frederic, Millard, Susan, Pettit, Allison R., Sims, Natalie A., Anginot, Adrienne, Guerton, Bernadette, Winkler, Ingrid G., Barbier, Valerie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline, Hutmacher, Dietmar W. and Levesque, Jean-Pierre (2015). Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle. Journal of Pathology, 236 (2), 229-240. doi: 10.1002/path.4519

Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs–G protein signaling in osteoblasts

Wattanachanya, Lalita, Wang, Liping, Millard, Susan M., Lu, Wei-Dar, O’Carroll, Dylan, Hsiao, Edward C., Conklin, Bruce R. and Nissenson, Robert A. (2015). Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs–G protein signaling in osteoblasts. Experimental Cell Research, 333 (2), 289-302. doi: 10.1016/j.yexcr.2015.02.009

Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification

Raggatt, Liza J., Wullschleger, Martin E., Alexander, Kylie A., Wu, Andy C. K., Millard, Susan M., Kaur, Simranpreet, Maugham, Michelle L., Gregory, Laura S., Steck, Roland and Pettit, Allison R. (2014). Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification. American Journal of Pathology, 184 (12), 3192-3204. doi: 10.1016/j.ajpath.2014.08.017

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription

Abankwa, Daniel, Millard, Susan M., Martel, Nick, Choong, Catherine S., Yang, Miao, Butler, Lisa M., Buchanan, Grant, Tilley, Wayne D., Ueki, Nobuhide, Hayman, Michael J. and Leong, Gary M. (2013). Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription. Bmc Biochemistry, 14 (1) 10, 10.1-10.8. doi: 10.1186/1471-2091-14-10

Mesenchymal stem cells for systemic therapy: shotgun approach or magic bullets?

Millard, Susan M. and Fisk, Nicholas M. (2013). Mesenchymal stem cells for systemic therapy: shotgun approach or magic bullets?. BioEssays, 35 (3), 173-182. doi: 10.1002/bies.201200087

Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation

Millard, Susan .M, Louie, Alyssa M., Wattanachanya, Lalita, Wronski, Thomas J., Conklin, Bruce R. and Nissenson, Robert A. (2011). Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation. Journal of Bone and Mineral Research, 26 (4), 822-832. doi: 10.1002/jbmr.273

Ligand-mediated activation of an engineered Gs G protein-coupled receptor in osteoblasts increases trabecular bone formation

Hsiao, Edward C., Millard, Susan M., Louie, Alyssa, Huang, Yong, Conklin, Bruce R. and Nissenson, Robert A. (2010). Ligand-mediated activation of an engineered Gs G protein-coupled receptor in osteoblasts increases trabecular bone formation. Molecular Endocrinology, 24 (3), 621-631. doi: 10.1210/me.2009-0424

The Ski proto-oncogene regulates body composition and suppresses lipogenesis

Leong, G. M., Kee, A. J., Millard, S. M., Martel, N., Eriksson, N., Turner, N., Cooney, G. J., Hardeman, E. C. and Muscat, G. E. O. (2010). The Ski proto-oncogene regulates body composition and suppresses lipogenesis. International Journal of Obesity, 34 (3), 524-536. doi: 10.1038/ijo.2009.265

Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells

Ramakrishnan, Sathiya N., Lau, Patrick, Crowther, Lisa M., Cleasby, Mark E., Millard, Susan, Leong, Gary M., Cooney, Gregory J. and Muscat, George E. O. (2009). Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells. Biochemical and Biophysical Research Communication, 388 (4), 654-659. doi: 10.1016/j.bbrc.2009.08.045

Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia

Peng, J., Bencsik, M., Louie, A., Lu, W., Millard, S., Nguyen, P., Burghardt, A., Majumdar, S., Wronski, T. J., Halloran, B., Conklin, B. R. and Nissenson, R. A. (2008). Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia. Endocrinology, 149 (3), 1329-1337. doi: 10.1210/en.2007-0235

The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X

Mouchantaf, Rania, Azakir, Bilal A., McPherson, Peter S., Millard, Susan M., Wood, Stephen A. and Angers, Annie (2006). The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X. Journal of Biological Chemistry, 281 (50), 38738-38747. doi: 10.1074/jbc.M605959200

Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes

Millard, Stephen A. and Wood, Susan M. (2006). Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes. Journal of Cell Biology, 173 (4), 463-468. doi: 10.1083/jcb.200602082

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology

Pettit, Allison, Batoon, Lena, Millard, Susan, Wu, Andy and Raggatt, Liza (2019). Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology. Annual Meeting of the American Society for Bone and Mineral Research, Orlando, FL, United States, 20-23 September, 2019. Hoboken, NJ, United States: Wiley-Blackwell Publishing Asia.

Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation

Millard, Susan, Wu, Andy, Kaur, Simran, He, Yaowu, Batoon, Lena, Hooper, John and Pettit, Allison (2018). Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation. Annual Meeting of the American Society for Bone and Mineral Research, Montréal, Quebéc, Canada, Sep 28-Oct 01, 2018. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1002/jbmr.3621

Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries

Tseng, Hsu-Wen, Alexander, Kylie, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Genet, Francois, Torossian, Frederic, Guerton, Bernadette, Anginot, Adrienne, Fleming, Whitney, Millard, Susan, Pettit, Allison, Sims, Natalie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Levesque, Jean Pierre (2018). Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries. Annual Meeting of the American Society for Bone and Mineral Research, Montreal Canada, September 28 - October 1 2018. Hoboken, NJ United States: Wiley.

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

Levesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Kaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages

Kaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157

Endogenous G(i) signaling in osteoblasts participates in sexually dimorphic regulation of cancellous bone structure

Millard, S., Louie, A., Manalac, C., Lu, W., Cotte, N., Wronski, T.J., Conklin, B. and Nissenson, R.A. (2009). Endogenous G(i) signaling in osteoblasts participates in sexually dimorphic regulation of cancellous bone structure. 2nd Joint Meeting of the International Bone and Mineral-Society/Australian New Zealand-Bone and Mineral Society, Sydney, Australia, 21-25 March 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.337

Endogenous G(i) Signaling in Osteoblasts Negatively Regulates Cortical Bone Formation

Millard, SM, Louie, A, Manalac, C, Lu, W, Cotte, N, Boudignon, B, Halloran, BP, Conklin, B and Nissenson, RA (2008). Endogenous G(i) Signaling in Osteoblasts Negatively Regulates Cortical Bone Formation. 30th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Montreal Canada, Sep 12-16, 2008. WILEY-BLACKWELL.

Expression of an Engineered G(s)-coupled Receptor, Rs1, in Mature Osteoblasts is Sufficient to Drive A Dramatic Anabolic Skeletal Response

Millard, SM, Boudignon, B, Louie, A, Lu, W, Halloran, BP, Conklin, B and Nissenson, RA (2008). Expression of an Engineered G(s)-coupled Receptor, Rs1, in Mature Osteoblasts is Sufficient to Drive A Dramatic Anabolic Skeletal Response. 30th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Montreal Canada, Sep 12-16, 2008. WILEY-BLACKWELL.

Ligand Activation of the Engineered G(s)-coupled Receptor Rs1 in Osteoblasts Promotes Trabecular Bone Formation

Hsiao, E, Millard, S, Louie, A, Boudignon, B, Manalac, C, Lu, W, Halloran, B, Conklin, B and Nissenson, R (2008). Ligand Activation of the Engineered G(s)-coupled Receptor Rs1 in Osteoblasts Promotes Trabecular Bone Formation. 30th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Montreal Canada, Sep 12-16, 2008. WILEY-BLACKWELL.

Designer G protein coupled receptors suggest opposing roles for Gs and Gi signaling in osteoblasts

Millard, SM, Peng, J, Benesik, M, Storer, A, Lu, W, Wronski, TJ, Conklin, B and Nissenson, RA (2007). Designer G protein coupled receptors suggest opposing roles for Gs and Gi signaling in osteoblasts. 29th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Honolulu Hi, Sep 16-19, 2007. AMER SOC BONE & MINERAL RES.

A role for the deubiquitylating enzyme FAM in cell-cell adhesion

Millard, SM and Wood, SA (2004). A role for the deubiquitylating enzyme FAM in cell-cell adhesion. Annual Meeting of the American-Society-for-Cell-Biology, Washington Dc, Dec 04-08, 2004. AMER SOC CELL BIOLOGY.