Professor Ian Yang

Head, PCH North (Conjoint)

Prince Charles Hospital Northside Clinical Unit
Faculty of Medicine
i.yang@uq.edu.au
+61 7 3139 5050

Overview

Professor Ian Yang is a Thoracic Physician and Director of Thoracic Medicine at The Prince Charles Hospital, and Head of the PCH-Northside Clinical Unit, School of Clinical Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Australia.

Research Interests

  • Clinical and translational research in chronic lung diseases
    Pathogenesis, diagnosis and treatment of chronic lung diseases, including COPD, asthma, lung cancer, mesothelioma and effects of air pollution

Research Impacts

His clinical work is in the field of thoracic medicine, and his research team is studying gene-environmental interaction in COPD, asthma, lung cancer and air pollution. He is involved in the training of higher degree students in translational research into lung diseases.

He is a Chair of the National COPD Guidelines Committee of the Lung Foundation Australia, and a member of the COPD Coordinating Committee. He is Chair of the Medical Programs and Research Advisory Committee of the Asthma Foundation Queensland NSW.

Qualifications

  • The Thoracic Society of Australia and New Zealand, The Thoracic Society of Australia and New Zealand
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Asian Pacific Society of Respirology, Asian Pacific Society of Respirology
  • Doctor of Philosophy, The University of Queensland
  • Postgraduate Diploma, University of Newcastle
  • Bachelor (Honours) of Medicine Surgery, The University of Queensland

Publications

  • Budden, Kurtis F, Shukla, Shakti D, Bowerman, Kate L, Vaughan, Annalicia, Gellatly, Shaan L, Wood, David L A, Lachner, Nancy, Idrees, Sobia, Rehman, Saima Firdous, Faiz, Alen, Patel, Vyoma K, Donovan, Chantal, Alemao, Charlotte A, Shen, Sj, Amorim, Nadia, Majumder, Rajib, Vanka, Kanth S, Mason, Jazz, Haw, Tatt Jhong, Tillet, Bree, Fricker, Michael, Keely, Simon, Hansbro, Nicole, Belz, Gabrielle T, Horvat, Jay, Ashhurst, Thomas, van Vreden, Caryn, McGuire, Helen, Fazekas de St Groth, Barbara ... Hansbro, Philip M (2024). Faecal microbial transfer and complex carbohydrates mediate protection against COPD. Gut, gutjnl-2023. doi: 10.1136/gutjnl-2023-330521

  • Thomas, Dennis, McDonald, Vanessa M., Stevens, Sean, Baraket, Melissa, Hodge, Sandra, James, Alan, Jenkins, Christine, Marks, Guy B., Peters, Matthew, Reynolds, Paul, Upham, John W., Yang, Ian A. and Gibson, Peter G. (2024). Azithromycin induced asthma remission in adults with persistent uncontrolled asthma: a secondary analysis of a randomised, double-blind, placebo-controlled trial. CHEST. doi: 10.1016/j.chest.2024.02.048

  • Thomas, Dennis, McDonald, Vanessa M., Stevens, Sean, Harvey, Erin S., Baraket, Melissa, Bardin, Philip, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Gillman, Andrew, Hew, Mark, Hodge, Sandra, James, Alan, Jenkins, Christine, Katelaris, Constance H., Katsoulotos, Gregory P., Langton, David, Lee, Joy, Marks, Guy, Peters, Matthew, Radhakrishna, Naghmeh, Reynolds, Paul N., Rimmer, Janet, Sivakumaran, Pathmanathan, Upham, John W., Wark, Peter, Yang, Ian A. and Gibson, Peter G. (2024). Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients. Allergy, 79 (2), 384-392. doi: 10.1111/all.15867

View all Publications

Grants

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Available Projects

  • Improving approaches to the early diagnosis, monitoring and management of patients with COPD

  • Genetics and epigenetics of ageing in the lung

  • Gene-environment interaction in the lung's response to exposure to air pollutants

View all Available Projects

Publications

Book Chapter

  • Yang, Ian A., Shaw, Janet G., Stephens, Edward K.H., Chee, Tian Mun, Duhig, Edwina E., Bowman, Rayleen V., Olive, Gerard N., Marshall, Henry M. and Fong, Kwun M. (2022). COPD: the risk of cancer and the impact on cancer care. Lung diseases and cancer. (pp. 91-104) edited by Peter M.A. Calverley, Miguel Ángel Martínez-García, Mina Gaga and Kwun M. Fong. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/2312508x.10018721

  • Mackintosh, John A., Duhig, Edwina E., Reddy, Taryn, Stephens, Edward K.H., Fong, Kwun M. and Yang, Ian A. (2022). Interstitial abnormalities from solid and haematological cancers. Lung diseases and cancer. (pp. 225-240) edited by Miguel Ángel Martínez-García, Mina Gaga, Kwun M. Fong and Peter M.A. Calverley. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/2312508x.10020221

  • Semasinghe Bandaralage, S. P., Slader, Simon, Leong, S., Yang, I. A., Bowman, R. V. and Fong, Kwun M. (2021). Differential diagnosis of mediastinal masses. Encyclopedia of respiratory medicine. (pp. 729-742) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-08-102723-3.00033-0

  • Goffinet, Céline, Marshall, H., Yang, Ian A., Bowman, R. V. and Fong, Kwun M. (2021). Metastases from lung cancer. Encyclopedia of respiratory medicine. (pp. 785-792) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-08-102723-3.00049-4

  • Olive, Gerard N., Marshall, Henry M., Yang, Ian A., Bowman, Rayleen V. and Fong, Kwun M. (2021). Overview of lung cancer. Encyclopedia of respiratory medicine. (pp. 621-633) edited by Sam M. Janes. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-08-102723-3.00031-7

  • Shaw, Janet G., Vaughan, Annalicia, Smith, Emma, Fong, Cai, Stevanovic, Svetlana and Yang, Ian A. (2019). Spirometry for chronic obstructive pulmonary disease due to inhalation of smoke from indoor fires used for cooking and heating. Revolutionizing tropical medicine: point‐of‐care tests, new imaging technologies and digital health. (pp. 306-326) edited by Kerry Atkinson and David Mabey. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119282686.ch20

  • Fong, Kwum M., Larsen, Jill E., Wright, Casey M., Sriram, Krishna, Davidson, Morgan, Daniels, Marissa, Sekido, Yoshitaka, Bowman, Rayleen V., Yang, Ian A. and Minna, John D. (2017). Molecular basis of lung carcinogenesis. The molecular basis of human cancer. (pp. 447-496) edited by William B. Coleman and Gregory J. Tsongalis. Totowa, NJ, United States: Humana Press. doi: 10.1007/978-1-59745-458-2_28

  • Holloway, John, Yang, Ian, Rosenwasser, Lanny J. and Holgate, Stephen T. (2011). Genetic aspects. World Allergy Organization (WAO) White Book on Allergy. (pp. 75-78) edited by Ruby Pawankar, Giorgio Walter Canonica, Stephen T. Holgate and Richard F. Lockey. Milwaukee, WI, U.S.A.: World Allergy Organization.

  • Fong, Kwun M., Bowman, Rayleen V., Yang, Ian A. and Miles, Kenneth A. (2007). Perfusion CT applications in lung cancer. Multi-Detector Computed Tomography in Oncology: CT Perfusion Imaging. (pp. 111-128) edited by Kenneth Miles, Chusilip Charnsangavej and Charles A. Cuenod. New York, United States: Informa Healthcare.

  • Yang, I. A., Kim, S. T. and Bell, S. C. (2005). Antiobiotics in chronic obstructive pulmonary disease, bronchiectasis and cystic fibrosis. Evidence-based Respiratory Medicine. (pp. 389-414) edited by P. Gibson. Carlton South, Australia: Blackwell Publishing Asia. doi: 10.1002/9780470987377.ch30

Journal Article

Conference Publication

  • Zahra, C. J., Chee, K., Yang, I. A. and Fong, K. M. (2023). Detecting KRAS Mutations in Peripheral Blood Extracellular Vesicles in Non-Small Cell Lung Cancer Using Digital Droplet PCR. NEW YORK: ELSEVIER SCIENCE INC.

  • Ngo, L., Woodman, R., Walters, T., Denman, R., Yang, I. and Ranasinghe, I. (2021). Long-term outcomes of 265,737 patients hospitalised with atrial fibrillation and atrial flutter from 2008 to 2015. OXFORD: OXFORD UNIV PRESS.

  • Hai Ngo, Linh Thi, Woodman, Richard, Denman, Russell A., Walters, Tomos E., Yang, Ian and Ranasinghe, Isuru (2021). Long-term outcomes of patients undergoing catheter ablation of atrial fibrillation: A bi-national cohort study. Heart Rhythm 2021, Boston, MA United States, 28-31July 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.hrthm.2021.06.336

  • Ngo, L., Woodman, R., Denman, R., Walters, T., Yang, I. and Ranasinghe, I. (2021). Long-term Outcomes of 265,677 patients hospitalised with Atrial Fibrillation and Flutter From 2008 to 2015. 69th CSANZ Annual Scientific Meeting 43rd Annual Scientific Meeting of the International Society for Heart Research ANZET 21, Online, 5-8 August 2021. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2021.06.154

  • Ngo, L., Woodman, R., Denman, R., Walters, T., Yang, I. and Ranasinghe, I. (2021). Long-term Outcomes of Patients Undergoing Catheter Ablation of Atrial Fibrillation: A Bi-National Cohort Study. 69th CSANZ Annual Scientific Meeting 43rd Annual Scientific Meeting of the International Society for Heart Research ANZET 21, Online, 5-8 August 2021. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2021.06.155

  • Marshall, H., Mclellan, R., Yang, I., Bowman, R. and Fong, K. (2020). Attitudes of Australian specialists to lung cancer screening with low dose computed tomography. Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell.

  • Simpson, Jodie, Barker, Daniel, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Baraket, Melissa and Gibson, Peter (2019). Azithromycin add-on therapy reduces airway inflammation and extracellular DNA: An AMAZES sub-study. European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September-2 October 2019. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5338

  • Barnett, Adrian, Yang, Ian, Hay, Karen, Ding, Hang, Bowman, Rayleen, Fong, Kwun and Marshall, Henry (2019). A meta-analysis of the effectiveness of smart phone applications to aid smoking cessation. European-Respiratory-Society (ERS) International Congress, Madrid Spain, 28 September-2 October 2019. London, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5134

  • Chee, T. M., Oey, H., Fong, K., Yang, I., Krause, L. and Bowman, R. (2019). Fusion genes identified from whole genome and whole transcriptome sequencing of malignant pleural mesothelioma tumours. IASLC 2019 World Conference on Lung Cancer, Barcelona, Spain, 7-10 September 2019. New York, NY, United States: Elsevier . doi: 10.1016/j.jtho.2019.08.697

  • O'Farrell, Hannah, Shaw, Janet, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Association between bacterial load and inflammatory gene expression in COPD exacerbations. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA3864

  • Cousins, J., Wood-Baker, R., Wark, P., Yang, I., Hutchinson, A., Sajkov, D., Gibson, P. and Mcdonald, V. (2018). Management of acute COPD exacerbations: Do we follow the guidelines?. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Adelaide, Australia, 23–27 March 2018. Hoboken, NJ United States: Wiley.

  • Vaughan, Annalicia, Stevanovic, Svetlana, Jafari, Mohammad, Bowman, Rayleen, Fong, Kwun, Ristovski, Zoran and Yang, Ian (2018). Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions. 28th International Congress of the European Respiratory Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA4243

  • Shaw, Janet, O'Farrell, Hannah, Ferry, Olivia, Fung, Pamela, Courtney, Deborah, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Sputum biospecimen quality and suitability for microbiome characterisation in COPD. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA5304

  • Vaughan, Annalicia, Stevanovic, Svetlana, Jafari, Mohammad, Miljevic, Branka, Ristovski, Zoran, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2017). Effects of N-acetylcysteine intervention in vitro on primary human bronchial epithelial cells exposed to diesel emissions. ANZSRS/TSANZ, Canberra, ACT, Australia, 24-28 March 2017. Richmond, VIC, Australia: Wiley-Blackwell.

  • Gibson, P., Reddel, H., Jenkins, C., Marks, G., Upham, J., Gillman, A., Thien, F., Sutherland, M., Rimmer, J., Katsoulotos, G., Cook, M., Yang, , Katelaris, C., Bowler, S., Langton, D., Robinson, P., Wright, C., Yozghatlian, , Burgess, S., Mcdonald, , Sivakumaran, P., Jaffe, A., Bowden, J., Guo, M., Wark, P., Yan, K. Y., Kritikos, V., Peters, M., Baraket, M. ... Bint, M. (2016). EFFECTIVENESS AND RESPONSE PREDICTORS OF OMALIZUMAB IN A SEVERE ALLERGIC ASTHMA POPULATION WITH A HIGH PREVALENCE OF COMORBIDITIES: THE AUSTRALIAN XOLAIR REGISTRY. HOBOKEN: WILEY-BLACKWELL.

  • Daniels, Marissa G., Krause, Lutz, Ellis, Jonathan J., Yang, Ian A., Bowman, Rayleen V., Relan, Vandana, Chee, Kelly, Goh, Felicia, Parris, Brielle, Morrison, Leanne, Martins, Maria, Passmore, Linda, McCaul, Elizabeth, Courtney, Deborah, Duhig, Edwina, Windsor, Morgan, Naidoo, Rishendran and Fong, Kwun M. (2016). Intratumoral genomic heterogeneity of primary pulmonary adenocarcinoma in never smokers. Meeting of the American-Association-for-Cancer-Research (AACR) Precision Medicine Series - Integrating Clinical Genomics and Cancer Therapy, Salt Lake City, UT United States, 13-16 June 2015. Philadelphia, PA United States: Elsevier. doi: 10.1158/1557-3265.PMSCLINGEN15-24

  • Dent, A., Bowman, R., Zimmerman, P., Fong, K. and Yang, I. (2015). Electronic nose as a tool for detecting COPD and emphysema in smokers. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Gold Coast, QLD, Australia, 27 March–1 April 2015. Richmond, VIC, Australia: Wiley-Blackwell.

  • Daniels, Marissa, Krause, Lutz, Ellis, Jonathan, Yang, Ian A., Bowman, Rayleen V., Relan, Vandana, Chee, Kelly, Goh, Felicia, Parris, Brielle, Morrison, Leanne, Martins, Maria, Mccaul, Elizabeth, Passmore, Linda, Courtney, Deborah, Duhig, Edwina, Naidoo, Rishendran, Fong, Kwun and Windsor, Morgan (2015). Inter-, and Intratumoural Genomic Heterogeneity of Primary Pulmonary Adenocarcinoma in Never Smokers. 16th World Conference on Cancer, Denver, CO United States, 6-9 September 2015. New York, NY United States: Elsevier.

  • Vaughan, A., Stevanovic, S., Morrison, L., Pourkhesalian, A., Rahman, M., Zare, A., Miljevic, B., Ristovski, Z., Goh, F., Relan, V, Bowman, R., Fong, K. and Yang, I (2015). Organic content of diesel emission particles and human bronchial epithelial cell responses to primary and aged diesel emissions. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting 2015, Gold Coast, Australia, 27 March – 1 April 2015. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/resp.12495_3

  • Hsiao, A., Kennett, C., Eeles, E., Whiting, E., Rowland, J., Fung, P., McNamara, J., Shaw, J., Ingham, J., Bowman, R., Fong, K. and Yang, I. (2014). Comprehensive Geriatric Assessment (CGA) and short term outcomes in frail older respiratory patients. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide, Australia, 4‐9 April 2014. Richmond, VIC, Australia: Wiley-Blackwell.

  • Vaughan, A., Stevanovic, S., Miljevic, B., Ristovski, Z., Relan, V., Goh, F., Bowman, R., Fong, K. and Yang, I. (2014). Diesel emission composition mediates cellular responses of primary human bronchial epithelial cells at an air-liquid interface in vitro. Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Adelaide, Australia, 4-9 April 2014. Richmond, VIC, Australia: Wiley-Blackwell.

  • Relan, V., Morrison, L., Chee, T., Yang, I., Fong, K. and Bowman, R. (2014). Drug resistant gene expression changes in carboplatin tolerant mesothelioma cells. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide, Australia, 4‐9 April 2014. Richmond, VIC, Australia: Wiley-Blackwell.

  • Hall, K., Kuys, S., Masel, P., Fong, K. and Yang, I. (2014). Outpatient physiotherapy improves quality of life for non CF bronchiectasis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide, Australia, 4-9 April 2014. New York, NY, United States: Elsevier.

  • Altenberger, Corinna, Heller, Gerwin, Schmid, Bianca, Ziegler, Barbara, Muellauer, Leonhard, Lang, Gyoergy, End-Pfuetzenreuter, Adelheid, Doeme, Balazs, Arns, Britt-Madeleine, Fong, Kwun M., Wright, Casey M., Yang, Ian A., Klepetko, Walter, Zielinski, Christoph C. and Zoechbauer-Mueller, Sabine (2014). Transcriptional regulation of SPAG6 by DNA methylation in NSCLCs. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-397

  • Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., Jenkins, C., Peters, M. and Gibson, P. G. (2013). Alternatives to Induced Sputum for Identifying Patients with Eosinophilic Asthma. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, 22 - 27 March 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12046

  • Daniels, Marissa, Sriram, Krishna, Duhig, Edwina, Clarke, Belinda, Dettrick, Andrew, Godbolt, David, Tran, Kayla, Windsor, Morgan, Naidoo, Rishendran, Matar, Kevin, Tam, Robert, Bowman, Rayleen, Yang, Ian and Fong, Kwun (2013). Comparative effectiveness of DDPCR for the detection of EGFR mutations. *, *, *. New York, NY, United States: Elsevier.

  • Goh, Felicia, Duhig, Edwina, Clarke, Belinda, Dettrick, Andrew, Godbolt, David, Tran, Kayla, Franz, Louise, Barr, Jeremy, Parsonson, Kylie, Martins, Maria, Davidson, Morgan, Wright, Casey, De laat, John, Shaw, Janet, Martin, Jennifer, Parris, Brielle, Shaw, Eloise, De Souza, Laura, Tjahjadi, Jane, Daniels, Marissa, Larsen, Jill E., Semmler, Annalese, Stockwell, Rachel, Savarimuthu, Santiyagu, Relan, Vandana, Sriram, Krishna, Campbell, Jennifer, Kim, Samuel, Tan, Maxine ... Fong, Kwun (2013). Heterogeneity in tumour content and necrosis in primary lung cancers: Implications for molecular analysis. 15th World Conference on Lung Cancer, Sydney, Australia, October 27-30, 2013. New York, United States: Elsevier. doi: 10.1097/01.JTO.0000438438.14562.c8

  • Hakim, R., Mccarthy, L., Masel, P. J., Bowman, R. V., Burke, A., Bazdar, S., Serginson, J. G. and Yang, I. A. (2013). Personalized care for COPD: the "COPD Snapshot". Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12045

  • Lee, Xiang-Wen, Leong, Steven, Marshall, Henry, Ayres, Jonny, Mohamed, Osman, Bowman, Rayleen, Yang, Ian and Fong, Kwun (2013). Pulmonary Nodule Detection by Junior Medical Staff Is Improved by Digital Tomosynthesis Compared to Chest X-Ray. 15th World Congress on Lung Cancer, Sydney, NSW Australia, 27-30 October 2013. Philadelphia, PA United States: Elsevier.

  • Dent, Annette G., Bowman, Rayleen, Zimmerman, Paul, Yang, Ian A. and Fong, Kwun M. (2013). Validation of electronic nose exhaled breath VOC profile in discriminating between subjects with early stage lung cancer and healthy never smokers. New York, NY, United States: Elsevier.

  • O'Hare, P. E., Ayres, J., O'Rourke, R., Slaughter, R. E., Marshall, H. M., Bowman, R. V., Fong, K. M. and Yang, I. A. (2013). Visual Coronary Artery Calcification Score On Thoracic Ct Predicts All-Cause Mortality in Patients with Copd. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, 22 - 27 March 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12045

  • Goddard, John R., Serginson, John, Mccarthy, Lisa, Waller, Rina, Bowman, Rayleen V., Fong, Kwun M. and Yang, Ian A. (2012). An evidence-based checklist for acute exacerbations of chronic obstructive pulmonary disease. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x

  • Relan, V., Schagen, J., Morrison, L., Martins, J., Clarke, B. E., Duhig, E. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2012). Discovery of new active drugs for treatment of malignant mesothelioma by screening the JHCCL clinical compound library. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra ACT, Australia, 30 March-4 April 2012. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02143.x

  • Garside, C. G., Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., Gibson, P. G. and Amazes Study Research Group (2012). Inflammatory subtypes of uncontrolled asthma in Australia. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x

  • Duhig, E. E., Clarke, B. E., Godbolt, D., Dettrick, A., Pauli, J., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). Interobserver agreement of lung adenocarcinoma diagnosis when applying the 2011 Iaslc/ats/ers Multidisciplinary Classification of Lung Adenocarcinoma. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Sriram, K. B., Relan, V, Clarke, B. E., Duhig, E. E., Windsor, M. N., Matar, K. S., Naidoo, R., Passmore, L., McCaul, E., Courtney, D., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). Pleural fluid cell-free dna integrity index and mesothelin to identify cytologically negative malignant pleural effusions including mesotheliomas. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Fong, K., Marshall, H., Bowman, R., Yang, I., Slaughter, R., Fuentes, M., Crossin, J., Leong, S., Ayres, J., Windsor, M., Redmond, S., McCaul, L., Passmore, L. and Zimmerman, P. (2012). Screening for lung cancer. RACP Future Directions in Health Congress 2012, Brisbane QLD, Australia, 6-9 May 2012. Richmond Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2012.02779.x

  • Goh, F., Daniels, M., Shaw, J. G., Courtney, D., Passmore, L., McCaul, L., Duhig, E., Clarke, B., Parsonson, K., Brady, J., Butler, D., Martins, M., Davidson, M., Wright, C. M., Martin, J., Morrison, L., Relan, V, Savarimuthu, F. S. M., Windsor, M. N., Matar, K. S., Naidoo, R., Tam, R., Colosimo, M., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). Screening lung Tumour tissue for whole genome sequencing. 4th Australian Lung Cancer Conference (ALCC), Adelaide, SA, Australia, 23-25 August 2012. Philadelphia, PA, United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Sriram, K. B., Relan, V, Clarke, B. E., Duhig, E. E., Windsor, M. N., Matar, K. S., Naidoo, R., Passmore, L., McCaul, E., Courtney, D., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). Telomere length in pleural fluid is not different between malignant and benign effusions. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Marshall, H. M., Bowman, R., V, Crossin, J., Lau, M. A., Slaughter, R. E., Ayres, J., Passmore, L. H., McCaul, E. M., Leong, S. C., Courtney, D. A., Windsor, M. N., Yang, I. A., Zimmerman, P., V., Hayes, T. J., Redmond, S. J., Lam, S. C., Tammemagi, M. C. and Fong, K. M. (2012). The Queensland Lung Cancer Screening Study: risk stratification using participant data and lung function tests can significantly increase screening effectiveness. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Duhig, E. E., Clarke, B. E., Godbolt, D., Dettrick, A., Pauli, J., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). The application of Fuhrman Nuclear Grade to lung adenocarcinoma and correlation with the Iaslc/ats/ers Multidisciplinary Classification of Adenocarcinoma and Survival in stage 1 disease. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Duhig, E. E., Clarke, B. E., Godbolt, D., Dettrick, A., Pauli, J., Yang, I. A., Bowman, R., V and Fong, K. M. (2012). The application of mitotic activity and necrosis to lung adenocarcinoma and correlation with the Iaslc/ats/ers multidisciplinary classification of adenocarcinoma in stage 1 disease. 4th Australian Lung Cancer Conference (ALCC), Adelaide SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Shaw, E., Wright, C., Bowman, R., V, Yang, I. A., Duhig, E., Clarke, L. and Fong, K. M. (2012). The expression of epithelial mesenchymal transition markers in early stage non-small cell lung cancer. 4th Australian Lung Cancer Conference (ALCC), Adelaide, SA, Australia, 23-25 August 2012. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/JTO.0b013e318268ff90

  • Mackintosh, John A., Marshall, Henry M., Yang, Ian A., Bowman, Rayleen V. and Fong, Kwun M. (2012). Volume doubling time of non-small cell lung cancer: Relationships to tumour and patient characteristics. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x

  • Sriram, K. B., Larsen, J. E., Francis, S. M. S., Wright, C. M., Mattar, K., Windsor, M., Clarke, B. E., Duhig, E. E., Hayward, N. K., Bowman, R. V., Yang, I. A. and Fong, K. M. (2011). Array-comparative genomic hybridization identifies novel copy number alterations in recurrent squamous cell lung cancer. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia, PA, United States: Lippincott Willams & Wilkins.

  • Relan, V., Schagen, J., Morrison, L., Parsonson, K. P., Clarke, B. E., Duhig, E. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2011). Discovery of Active New Drugs in Malignant Mesothelioma. European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical Oncology, Advocacy and Care (2011), Stockholm, Sweden, 23-27 September 2011. OXFORD: ELSEVIER SCI LTD. doi: 10.1016/S0959-8049(11)70811-5

  • Dent, A., Bowman, R., Zimmerman, P, Yang, I. and Fong, K. (2011). Electronic nose distinguishes lung cancer from healthly smoking controls. 3rd Australian Lung Cancer Conference (ALCC), Melbourne, Australia, 6-9 October 2010. Philadelphia PA, United States: Lippincott Williams & Wilkins.

  • Sriram, K. B., Tan, M. E., Savarimuthu Francis, S. M., Wright, C. M., Relan, V., Martins, M. U., Bowman, R. V., Yang, I. A. and Fong, K. M. (2011). Evaluation of EGFR mutations in NSCLC using ME-PCR and HRM. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia PA, United States: Lippincott Willams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc

  • Relan, V., Quinn, K. R., Wright, C. M., Savarimuthu, S. M., Tan, M. E., Clarke, B. E., Duhig, E. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2011). Genetic changes in two cell lines from human malignant mesothelioma during long term culturing. 3rd Australian Lung Cancer Conference (ALCC), Melbourne, Australia, 6-9 October 2010. Philadelphia PA, United States: Lippincott Williams & Wilkins.

  • Lwin, Zarnie, Day, Heather, Baade, Peter D., Aitken, Joanne F., Yang, Ian A., Bowman, Rayleen and Fong, Kwun M. (2011). Improving lung cancer specific outcome when access is the key-are we there yet?. In: , , (S1390-S1391). .

  • Wright, C. M., Francis, S. M. S., Sriram, K. B., Quinn, K. R., Stark, M. S., Hayward, N. K., Yang, I. A., Bowman, R. V. and Fong, K. M. (2011). Mapping the lung cancer methylome. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-9 October 2010. Philadelphia PA, United States: Lippincott Williams & Wilkins.

  • Relan, V., Bowman, R. V., Yang, I. A. and Fong, K. M. (2011). Merkel cell polyoma virus in lung cancer. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia PA, United States: Lippincott Willams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc

  • Thomas, J. D., Mohammed, O., Slaughter, R. E., Feuntes, M., Crossin, J., Marshall, H., Wright, C. M., Martins, M. U., Tan, M. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2011). Relationships between pleural plaques, lung asbestos content and asbestos exposure in Australians with or at risk of lung cancer. 3rd Australian Lung Cancer Conference (ALCC), Melbourne, Australia, 6-9 October 2010. Philadelphia PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc

  • Duhig, Edwina, Clarke, Belinda, Martins, Maria, Goh, Felicia, Yang, Ian, Matar, Kevin, Windsor, Morgan, Zimmerman, Paul, Davidson, Morgan, Wright, Casey, Bowman, Rayleen and Fong, Kwun M. (2011). Systematic quantification of tumour content in cryopreserved samples stored in a lung tumour bank. *, *, *. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

  • Rassam, L. J., Sinhal, N. P., Mackenzie, H., Bowman, R. V., Fong, K. M., Yang, I. A., Pratt, G., Fay, M., Hughes, B., Windsor, M. F. and Matar, K. (2011). The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia PA, United States: Lippincott Willams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc

  • Martins, M. U., Quinn, K. R., Savarimuthu Francis, S. M., Wright, C. M., Tan, M. E., Passmore, L. H., McCaul, E., Relan, V., Sriram, K. B., Davidson, M. R., De Laat, J. A., Parris, B. A., Campbell, J., Shaw, E. F., Tjahjadi, J., Hunter, S. C., Larsen, J. E., Clarke, B. E., Duhig, E. E., Zimmerman, P. V., Yang, I. A., Bowman, R. V. and Fong, K. M. (2010). Banking of tissues and body fluids for translational lung research. The Thoracic Society of Australia & New Zealand (TSANZ) Annual Scientific Meeting 2010, Brisbane, Qld, Australia, 19-24 March, 2010. Carlton, VIC, Australia: Blackwell Science. doi: 10.1111/j.1440-1843.2010.01736.x

  • Yang, I (2010). COMMON PATHOGENETIC MECHANISMS OF COPD AND LUNG CANCER. 15th Congress of the Asian Pacific Society of Respirology, Manila, Philippines, 22-25 November 2010.

  • Relan, V., Quinn, K. R., Tan, M. E., Wright, C. W., Clarke, B. E., Duhig, E. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2010). Characterization of cell lines from human malignant mesothelioma. The Thoracic Society of Australia & New Zealand (TSANZ) Annual Scientific Meeting 2010, Brisbane, Australia, 19-24 March 2010. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2010.01736.x

  • Relan, V., Quinn, K. R., Wright, C. M., Savarimuthu, S. M., Tan, M. E., Clarke, B. E., Duhig, E. E., Yang, I. A., Fong, K. M. and Bowman, R. V. (2010). Genetic changes in cell lines from human malignant mesothelioma during long term culturing. Brisbane 2010: The Joint TSANZ & ANZSRS Annual Scientific Meetings, Brisbane, QLD, Australia, 19–24 March 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2010.01736.x

  • Yang, Ian A., Swadling, Barbara, Bradbear, Robyn, Hatfield, Laurel, Stride, Peter J.O., Livett, Mark, Wright, Morgan, Baker, Peter G., Lake, Fiona, Caputo, Lisa, Peterson, Ray, McAllister, Lindy and Eley, Diann (2010). Learning in the Clinical Setting (LICS): A pilot study at the Northside Clinical School and Rural Clinical School. Medical Education Teaching and Learning Conference, Herston, Brisbane, Australia, 5 November 2010.

  • Yang, Ian (2010). Practical Implementation of COPD Guidelines in the Asia-Pacific region: Consensus formation. Post Graduate Course 15th Congress of the APSR, Manila, Philippines, 22-25 November 2010.

  • Chen, L., Meyers, D., Semmler, A.B., Yang, I., Pakorn, L., Lucas, M., Jovarsky, G., Savarimuthu, S., Galbraith, A., Parsonage, W. and Molenaar, P. (2006). Beta1-adrenoceptor (AR) Arg389Gly polymorphisms affect responses to carvedilol in patients with idiopathic dilated cardiomyopathy. 15th World Congress of Pharmacology, Beijing, China, 2nd - 7th July, 2006. China: Chinese Pharmacological Society.

  • Molenaar, P., Chen, Lu, Meyers, E., Javorsky, G., Burstow, M., Lucas, P., Lolekha, J., Atherton, A., Semmler, A. B., Savarimuthu, S., Fong, K. M., Yang, I. A., Galbraith, A. and Parsonage, W. A. (2006). Carvedilol causes a greater increase in heart function in idiopathic dilated cardiomyopathy patients with ARG389-compared to GLY389 Beta1-adrenoceptors. The Australian Health and Medical Research Congress, Melbourn, Australia, 26th November - 1st December, 2006. Australia: Australian Govenment NHMRC.

  • Yang, I. A., Kim, S. T. and Bell, S. C. (2005). Antibiotics for acute exacerbations of COPD: A systematic review. 2005 Annual Scientific Meeting The Thoracic Society of Australia and New Zealand, Perth, Australia, 18-23 March, 2005. Carlton South, Victoria: Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2005.00663.x-i1

  • Kim, S. T., Yang, I. A. and Bell, S. C. (2005). Antibiotics in cystic fibrosis (CF): A systematic review. Array, Crete, Greece, 22-25 Jun, 2005. Amsterdam, Netherlands: Elsevier BV.

  • Kim, S. T., Yang, I. A. and Bell, S. C. (2005). Antibiotics in cystic fibrosis (CF): A systematic review. 2005 Annual Scientific Meeting The Thoracic Society of Australia and New Zealand, Perth, Australia, 18-23 March, 2005. Carlton South, Victoria: Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2005.00663.x-i1

  • Kim, S. T., Passmore, L., Dent, A. G., Slaughter, R., Yang, I. A., Fong, K. M., Zimmerman, P. V. and Bell, S. C. (2005). Gender difference in prevalence of non-cystic fibrosis bronchiectasis (NCFB) does not influence clinical phenotype. 2005 Annual Scientific Meeting The Thoracic Society of Australia and New Zealand, Perth, Australia, 18-23 March, 2005. Carlton South, Victoria: Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2005.00663.x-i1

  • Molenaar, P., Russell, F. D., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L. and West, M. J. (2002). The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium. American Heart Association Scientific Sessions 2002, Chicago, 17-20 Nov, 2002. Hagerstown, U.S.A.: Lippincott Williams & Wilkins.

  • Wolter, J. M., Seeney, S. L., Yang, I. A., Bowler, S. D., Bell, S. and Mccormack, J. G. (2000). Azithromycin (AZM) reduced TNF- release from lipopolysachharide (LPS)-stimulated mononuclear cells (PBMC) in cystic fibrosis (CF). ASID Annual Scientific Meeting, Laura, NSW, 15-19 April, 2001. Balgowlah NSW: ADIS Press Australia.

  • Bell, S., Wolter, J. M., Seeney, S. L., Gan, R., Yang, I., Bowler, S. D. and Mccormack, J. G. (2000). Azithromycin (AZM) reduces TNF- release from lipopolysachcharide (LPS) - stimulated mononuclear cells (PBMC) in cystic fibrosis. Fourteenth Annual North American Cystic Fibrosis Conference, Baltimore Maryland, USA, 9-12 Novembe, 2000. New York, USA: Wiley Liss, Div John Wiley & Sons.

  • Gan, R., Bowler, S. D., Seeney, S. L., Wolter, J.M., Masel, P. J., Bunting, J., Tunnicliffe, A. M., Rabnott, G. C., Yang, I. A. and Bell, S. (2000). Tumour necrosis factor (TNF ), myeloperoxides (MPO) and interleukin-1 receptor antagonist polymorphisms in cystic fibrosis.. Fourteenth Annual North American Cystic Fibrosis Conference, Baltimore Maryland, USA, 9-12 Novewmber, 2000. New York USA: Wiley-Liss.

  • Yang, I. A., Gan, R., Tunnicliffe, A. M., Rabnott, G. C., Slaughter, R., Zimmerman, P.V. and Fong, K. M. (1999). GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD). Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society of Qld..

  • Gan, R., Yang, I. A., Tunnicliffe, A. M., Rabnott, G. C. and Fong, K. M. (1999). GSTM1 and GSTT1 genotypes in Australians with NSCLC. Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society.

  • Gan, R., Yang, I., Tunnicliffe, A. M., Rabnott, G. C., Bowman, R., Zimmerman, P.V. and Fong, K. M. (1999). GSTM1 genotypes in Australian patients with NSCLC. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

  • Yang, I. A., Gan, R., Tunniclife, A. M., Rabnott, G. C., Zimmerman, P.V. and Fong, K. M. (1999). GSTT1 and GSTM1 polymorphisms in Australian chronic obstructive pulmonary disease (COPD) patients. European Society Annual Congress, Madrid, Spain, 9 - 13 Oct, 1999. Copenhagen, Denmark: European Respiratory Society & Munksgaard Int. Publishers.

  • Moloney, C., Fong, K. M., Yang, I., Reilly, R. and Zimmerman, P. V. (1999). Health informatics in nursing education, research and quality assurance for asthma. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

  • Yang, I., Slaughter, R., Roszkowski, A., Fong, K. M. and Zimmerman, P. V. (1999). Quantification of pulmonary emphysema using high-resolution computed tomography. Heart and Lungs., Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

  • Douglas, J. A., Yang, I., Rabnott, G. C., Tunnicliffe, A. M., McCarthy, J. B., Zimmerman, P. V. and Fong, K. M. (1999). b2 adrenergic receptor genotypes in severe asthma. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

  • Rabnott, G. C., Tunnicliffe, A. M., Yang, I. A., Douglas, J. A., Shaw, J., McCarthy, J. B., Zimmerman, P. V. and Fong, K. M. (1999). b2 adrenoceptor genotypes and life-threatening asthma. Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society of Qld..

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • Improving approaches to the early diagnosis, monitoring and management of patients with COPD

  • Genetics and epigenetics of ageing in the lung

  • Gene-environment interaction in the lung's response to exposure to air pollutants