Dr Dan Yuan is currently a Lecturer in the School of Mechanical and Mining Engineering (SoMME) at the University of Queensland. She completed her PhD at the University of Wollongong (UOW) in 2018. After graduation, she continued her research at UOW as an Associate Research Fellow. From 2019 to 2021, she was a JSPS Research Fellow in the Department of Chemistry, Faculty of Science, University of Tokyo. From 2021 to 2022, she worked as an Alfred Deakin Research Fellow at Deakin University.
Based on the micro-nano devices, she was doing interdisciplinary research of mechatronics, chemistry, physics, optics, environmental and biomedical applications, aiming at addressing real-life challenges in both environment and biomedicine. Her research interests are microfluidics, microfabrication, development of point-of-need devices for environmental and biomedical applications, intelligent image activated cell sorting, and smart sensors, materials and platforms.
In less than 10 years’ research time, she published 57 peer-reviewed journal articles which have received > 2500 citations. The prestigious journals include Adv. Funct. Mater., Nat. Commun., Small, Lab Chip, Microsystems & Nanoengineering, and Anal. Chem. She currently has an h-index of 25. She was the Guest Editor for Biosensors (2022), Frontiers in Medical Technology (2021-2022); regular independent reviewer for more than 10 international journals such as ACS Nano, Lab on a Chip, Analytical Chemistry, Microsystems and Nanoengineering, Scientific Reports, IEEE Transactions on Mechatronics, Microfluidics and Nanofluidics, Cytometry Part A. etc. She was awarded the prestigious Alfred Deakin Research Fellowship and JSPS Research Fellowship.
Master and PhD positions are opening. The potential research projects include physics of fluid flow (especially non-Newtonian fluids) in micro/nano-channels, manipulation and separation of micro-/nanoparticles and fluid control, development of point-of-need devices for environmental and biomedical applications (e.g. disease diagnosis and therapeutics), intelligent microfluidics. Candidates with backgrounds in engineering (e.g., mechanical, mechatronics, materials, chemical and biomedical etc.), information technology, physics and biomedicine are welcome to enquiry.
PhD Scholarship is available:
https://study.uq.edu.au/study-options/phd-mphil-professional-doctorate/projects/viscoelastic-microfluidics-biomedical-and-environmental-applications
Dr Dan Yuan is a lead researcher in the field of viscoelastic microfluidics and its applications. She has developed comprehensive understanding of fundamental physics for particle migration in microfluidics especially viscoelastic microfluidics, which could expand the boundary of current knowledge. Also, she has developed cutting edge microfluidic technologies for particle and cell manipulation and separation, aiming at addressing real-life challenges in both biomedicine and environment. Her research achievements and emerging reputation have been acknowledged by the broader scientific community. She was awarded the competitive Alfred Deakin Research Fellowship and awarded JSPS Fellowship as a chief investigator and secured $378K AUD research funding in total.
She was the first to develop viscoelastic fluids-based microdevices for cell manipulation and apply them to extract blood plasma from blood with ultra-high purity (Lab Chip, 2016, 16(20): 3919-3928.). This work has attracted international interests due to its potential in cancer diagnostics and prognosis, as evidenced by reports of her discovery by worldwide media in 2017: Health Canal (United States); Technology Networks (United Kingdom); UOW (University of Wollongong) news (Australia); X-MOL (China); et al. This ground-breaking research has been selected as the cover page of Lab Chip. Her work of developing viscoelastic microfluidic devices for cell purification (Lab Chip, 2019, 19(17): 2811-2821.) was selected as the cover page of Lab Chip, and was listed as one of Lab Chip’s highest citing papers contributing to its Impact Factor 7.517 (with 19 alone in 2021). This novel platform technology has started to transform the way cells are identified and purified, and is also paving the way for addressing problems with microalgae contamination in industrial processes. In addition to the size-based cell manipulation, she also pioneered the area of shape-based separation techniques and applied this to the separation of cyanobacteria, demonstrating the ability to manipulate cells based on morphologies and with a size of >100 μm (Anal. Chem. 2021, 93, 37, 12648–12654). This is a revolutionary achievement opening opportunities and applications in research fields not yet employing microfluidic technologies. This work was featured as a cover page article and has been interviewed and reported by media X-MOL (China). Her review article on the recent progress of particle migration in viscoelastic fluid (Lab Chip. 2018 18 (4): 551-567.) was listed as Web of Science Highly Cited paper.
Journal Article: Abridged solid-phase extraction with alkaline Poly(ethylene) glycol lysis (ASAP) for direct DNA amplification
Lee, Soo Min, Nai, Yi H., Doeven, Egan H., Balakrishnan, Hari Kalathil, Yuan, Dan and Guijt, Rosanne M. (2024). Abridged solid-phase extraction with alkaline Poly(ethylene) glycol lysis (ASAP) for direct DNA amplification. Talanta, 266 (Pt 2) 125006, 1-8. doi: 10.1016/j.talanta.2023.125006
Journal Article: 3D printed porous membrane integrated devices to study the chemoattractant induced behavioural response of aquatic organisms
Kalathil Balakrishnan, Hari, Schultz, Aaron G., Lee, Soomin, Alexander, Richard, Dumee, Ludovic, Doeven, Egan H., Yuan, Dan and Guijt, Rosanne Marieke (2023). 3D printed porous membrane integrated devices to study the chemoattractant induced behavioural response of aquatic organisms. Lab on a Chip, 24 (3), 505-516. doi: 10.1039/d3lc00488k
Journal Article: An automated and intelligent microfluidic platform for microalgae detection and monitoring
Zheng, Jiahao, Cole, Tim, Zhang, Yuxin, Yuan, Dan and Tang, Shi-Yang (2023). An automated and intelligent microfluidic platform for microalgae detection and monitoring. Lab On a Chip, 24 (2), 244-253. doi: 10.1039/d3lc00851g
Deciphering the mechanisms of object manipulation with viscoelastic fluids
(2024–2027) ARC Discovery Early Career Researcher Award
Development of object manipulation techniques with viscoelastic fluids toward efficient environmental monitoring
Doctor Philosophy
Viscoelastic Microfluidics for Biomedical and Environmental Applications
Project summary: Use forces generated by fluids that are both viscous and elastic to help address challenges in biomedicine and the environment.
Lee, Soo Min, Nai, Yi H., Doeven, Egan H., Balakrishnan, Hari Kalathil, Yuan, Dan and Guijt, Rosanne M. (2024). Abridged solid-phase extraction with alkaline Poly(ethylene) glycol lysis (ASAP) for direct DNA amplification. Talanta, 266 (Pt 2) 125006, 1-8. doi: 10.1016/j.talanta.2023.125006
Kalathil Balakrishnan, Hari, Schultz, Aaron G., Lee, Soomin, Alexander, Richard, Dumee, Ludovic, Doeven, Egan H., Yuan, Dan and Guijt, Rosanne Marieke (2023). 3D printed porous membrane integrated devices to study the chemoattractant induced behavioural response of aquatic organisms. Lab on a Chip, 24 (3), 505-516. doi: 10.1039/d3lc00488k
An automated and intelligent microfluidic platform for microalgae detection and monitoring
Zheng, Jiahao, Cole, Tim, Zhang, Yuxin, Yuan, Dan and Tang, Shi-Yang (2023). An automated and intelligent microfluidic platform for microalgae detection and monitoring. Lab On a Chip, 24 (2), 244-253. doi: 10.1039/d3lc00851g
Chemical Trends in Sample Preparation for Nucleic Acid Amplification Testing (NAAT): A Review
Lee, Soo Min, Balakrishnan, Hari Kalathil, Doeven, Egan H., Yuan, Dan and Guijt, Rosanne M. (2023). Chemical Trends in Sample Preparation for Nucleic Acid Amplification Testing (NAAT): A Review. Biosensors, 13 (11) 980, 980. doi: 10.3390/bios13110980
Development of a pumpless acoustofluidic device for rapid food pathogen detection
Nilghaz, Azadeh, Lee, Soo Min, Su, Hongli, Yuan, Dan, Tian, Junfei, Guijt, Rosanne M. and Wang, Xungai (2023). Development of a pumpless acoustofluidic device for rapid food pathogen detection. Analytica Chimica Acta, 1275 341581, 341581. doi: 10.1016/j.aca.2023.341581
A novel microparticle size sorting technology based on sheath flow stable expansion regimes
Zhang, Boran, Zhao, Wenhan, Yuan, Dan, Wang, Tiao and Wu, Wenshuai (2023). A novel microparticle size sorting technology based on sheath flow stable expansion regimes. Physics of Fluids, 35 (5) 052018. doi: 10.1063/5.0152581
Wang, Tiao, Yuan, Dan, Wan, Wuyi and Zhang, Boran (2023). Numerical study of viscoelastic microfluidic particle manipulation in a microchannel with asymmetrical expansions. Micromachines, 14 (5) 915, 1-15. doi: 10.3390/mi14050915
Balakrishnan, Hari Kalathil, Dumée, Ludovic F., Merenda, Andrea, Aubry, Cyril, Yuan, Dan, Doeven, Egan H. and Guijt, Rosanne M. (2023). 3D printing functionally graded porous materials for simultaneous fabrication of dense and porous structures in membrane‐integrated fluidic devices. Small Structures, 4 (5) 2200314, 1-11. doi: 10.1002/sstr.202200314
3D printed integrated nanoporous membranes for electroextraction of DNA
Kalathil Balakrishnan, Hari, Lee, Soo Min, Dumée, Ludovic F., Doeven, Egan H., Alexander, Richard, Yuan, Dan and Guijt, Rosanne M. (2023). 3D printed integrated nanoporous membranes for electroextraction of DNA. Nanoscale, 15 (24), 10371-10382. doi: 10.1039/d2nr07178a
Matsumura, Hiroki, Shen, Larina Tzu-Wei, Isozaki, Akihiro, Mikami, Hideharu, Yuan, Dan, Miura, Taichi, Kondo, Yuto, Mori, Tomoko, Kusumoto, Yoshika, Nishikawa, Masako, Yasumoto, Atsushi, Ueda, Aya, Bando, Hiroko, Hara, Hisato, Liu, Yuhong, Deng, Yunjie, Sonoshita, Masahiro, Yatomi, Yutaka, Goda, Keisuke and Matsusaka, Satoshi (2023). Virtual-freezing fluorescence imaging flow cytometry with 5-aminolevulinic acid stimulation and antibody labeling for detecting all forms of circulating tumor cells. Lab on a Chip, 23 (6), 1561-1575. doi: 10.1039/d2lc00856d
Experimental exploration on stable expansion phenomenon of sheath flow in viscous microfluidics
Zhao, Wenhan, Wu, Wenshuai, Yuan, Dan, Zou, Siyuan, Yang, Fan, Zhao, Qianbin, Mehmood, Kashif and Zhang, Boran (2022). Experimental exploration on stable expansion phenomenon of sheath flow in viscous microfluidics. Physics of Fluids, 34 (12) 122002. doi: 10.1063/5.0129764
Length-based separation of Bacillus subtilis bacterial populations by viscoelastic microfluidics
Liu, Ping, Liu, Hangrui, Semenec, Lucie, Yuan, Dan, Yan, Sheng, Cain, Amy K. and Li, Ming (2022). Length-based separation of Bacillus subtilis bacterial populations by viscoelastic microfluidics. Microsystems and Nanoengineering, 8 (1) 7, 1-11. doi: 10.1038/s41378-021-00333-3
Lee, Soo Min, Balakrishnan, Hari Kalathil, Yuan, Dan, Nai, Yi Heng and Guijt, Rosanne M. (2022). Erratum to “Perspective - What constitutes a quality analytical paper: Microfluidics and Flow analysis” [Talanta Open, 2021, 100055](S2666831921000254)(10.1016/j.talo.2021.100055). Talanta Open, 5 100090, 100090. doi: 10.1016/j.talo.2022.100090
Multiphysics microfluidics for cell manipulation and separation: A review
Cha, Haotian, Fallahi, Hedieh, Dai, Yuchen, Yuan, Dan, An, Hongjie, Nguyen, Nam-Trung and Zhang, Jun (2022). Multiphysics microfluidics for cell manipulation and separation: A review. Lab on a Chip, 22 (3), 423-444. doi: 10.1039/d1lc00869b
Perspective - what constitutes a quality analytical paper: microfluidics and flow analysis
Lee, Soo Min, Balakrishnan, Hari Kalathil, Yuan, Dan, Nai, Yi Heng and Guijt, Rosanne M. (2021). Perspective - what constitutes a quality analytical paper: microfluidics and flow analysis. Talanta Open, 4 100055, 1-5. doi: 10.1016/j.talo.2021.100055
Investigation of viscoelastic focusing of particles and cells in a zigzag microchannel
Yuan, Dan, Yadav, Sharda, Ta, Hang T., Fallahi, Hedieh, An, Hongjie, Kashaninejad, Navid, Ooi, Chin Hong, Nguyen, Nam‐Trung and Zhang, Jun (2021). Investigation of viscoelastic focusing of particles and cells in a zigzag microchannel. Electrophoresis, 42 (21-22), 2230-2237. doi: 10.1002/elps.202100126
Sheathless separation of cyanobacterial Anabaena by shape using viscoelastic microfluidics
Yuan, Dan, Yan, Sheng, Zhang, Jun, Guijt, Rosanne M., Zhao, Qianbin and Li, Weihua (2021). Sheathless separation of cyanobacterial Anabaena by shape using viscoelastic microfluidics. Analytical Chemistry, 93 (37), 12648-12654. doi: 10.1021/acs.analchem.1c02389
Isozaki, Akihiro, Goda, Keisuke, Xu, Muzhen, Harmon, Jeffrey, Yuan, Dan, Yan, Sheng, Lei, Cheng, Hiramatsu, Kotaro, Zhou, Yuqi, Loo, Mun Hong and Hasunuma, Tomohisa (2021). Morphological indicator for directed evolution of euglena gracilis with a high heavy metal removal efficiency. Environmental Science and Technology, 55 (12), 7880-7889. doi: 10.1021/acs.est.0c05278
Continuous microfluidic 3D focusing enabling microflow cytometry for single-cell analysis
Yan, Sheng and Yuan, Dan (2021). Continuous microfluidic 3D focusing enabling microflow cytometry for single-cell analysis. Talanta, 221 121401, 1-15. doi: 10.1016/j.talanta.2020.121401
Modular off-chip emulsion generator enabled by a revolving needle
Zhang, Yuxin, Zhao, Qianbin, Yuan, Dan, Liu, Hangrui, Yun, Guolin, Lu, Hongda, Li, Ming, Guo, Jinhong, Li, Weihua and Tang, Shi-Yang (2020). Modular off-chip emulsion generator enabled by a revolving needle. Lab on a Chip, 20 (24), 4592-4599. doi: 10.1039/d0lc00939c
Liu, Ping, Liu, Hangrui, Yuan, Dan, Jang, Daniel, Yan, Sheng and Li, Ming (2020). Separation and enrichment of yeast Saccharomyces cerevisiae by shape using viscoelastic microfluidics. Analytical Chemistry, 93 (3), 1586-1595. doi: 10.1021/acs.analchem.0c03990
Liquid metal composites with anisotropic and unconventional piezoconductivity
Yun, Guolin, Tang, Shi-Yang, Zhao, Qianbin, Zhang, Yuxin, Lu, Hongda, Yuan, Dan, Sun, Shuaishuai, Deng, Lei, Dickey, Michael D. and Li, Weihua (2020). Liquid metal composites with anisotropic and unconventional piezoconductivity. Matter, 3 (3), 824-841. doi: 10.1016/j.matt.2020.05.022
Zhang, Jun, Chintalaramulu, Naveen, Vadivelu, Raja, An, Hongjie, Yuan, Dan, Jin, Jing, Ooi, Chin Hong, Cock, Ian Edwin, Li, Weihua and Nguyen, Nam-Trung (2020). Inertial microfluidic purification of floating cancer cells for drug screening and three-dimensional tumor models. Analytical Chemistry, 92 (17), 11558-11564. doi: 10.1021/acs.analchem.0c00273
A review of secondary flow in inertial microfluidics
Zhao, Qianbin, Yuan, Dan, Zhang, Jun and Li, Weihua (2020). A review of secondary flow in inertial microfluidics. Micromachines, 11 (5) 461, 1-23. doi: 10.3390/MI11050461
Intelligent image-activated cell sorting 2.0
Isozaki, Akihiro, Mikami, Hideharu, Tezuka, Hiroshi, Matsumura, Hiroki, Huang, Kangrui, Akamine, Marino, Hiramatsu, Kotaro, Iino, Takanori, Ito, Takuro, Karakawa, Hiroshi, Kasai, Yusuke, Li, Yan, Nakagawa, Yuta, Ohnuki, Shinsuke, Ota, Tadataka, Qian, Yong, Sakuma, Shinya, Sekiya, Takeichiro, Shirasaki, Yoshitaka, Suzuki, Nobutake, Tayyabi, Ehsen, Wakamiya, Tsubasa, Xu, Muzhen, Yamagishi, Mai, Yan, Haochen, Yu, Qiang, Yan, Sheng, Yuan, Dan, Zhang, Wei ... Goda, Keisuke (2020). Intelligent image-activated cell sorting 2.0. Lab on a Chip, 20 (13), 2263-2273. doi: 10.1039/d0lc00080a
Liquid metal-filled magnetorheological elastomer with positive piezoconductivity
Yun, Guolin, Tang, Shi-Yang, Sun, Shuaishuai, Yuan, Dan, Zhao, Qianbin, Deng, Lei, Yan, Sheng, Du, Haiping, Dickey, Michael D. and Li, Weihua (2019). Liquid metal-filled magnetorheological elastomer with positive piezoconductivity. Nature Communications, 10 (1) 1300, 1-9. doi: 10.1038/s41467-019-09325-4
Yuan, Dan, Zhao, Qianbin, Yan, Sheng, Tang, Shi-Yang, Zhang, Yuxin, Yun, Guolin, Nguyen, Nam-Trung, Zhang, Jun, Li, Ming and Li, Weihua (2019). Sheathless separation of microalgae from bacteria using a simple straight channel based on viscoelastic microfluidics. Lab on a Chip, 19 (17), 2811-2821. doi: 10.1039/c9lc00482c
Phase separation in liquid metal nanoparticles
Tang, Shi-Yang, Mitchell, David R. G., Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Zhang, Yuxin, Qiao, Ruirui, Lin, Yiliang, Dickey, Michael D. and Li, Weihua (2019). Phase separation in liquid metal nanoparticles. Matter, 1 (1), 192-204. doi: 10.1016/j.matt.2019.03.001
Zhang, Yuxin, Tang, Shi-Yang, Zhao, Qianbin, Yun, Guolin, Yuan, Dan and Li, Weihua (2019). High-throughput production of uniformly sized liquid metal microdroplets using submerged electrodispersion. Applied Physics Letters, 114 (15) 154101, 154101. doi: 10.1063/1.5086376
Fundamentals of differential particle inertial focusing in symmetric sinusoidal microchannels
Zhang, Jun, Yuan, Dan, Zhao, Qianbin, Teo, Adrian J. T., Yan, Sheng, Ooi, Chin Hong, Li, Weihua and Nguyen, Nam-Trung (2019). Fundamentals of differential particle inertial focusing in symmetric sinusoidal microchannels. Analytical Chemistry, 91 (6), 4077-4084. doi: 10.1021/acs.analchem.8b05712
High-throughput, off-chip microdroplet generator enabled by a spinning conical frustum
Tang, Shi-Yang, Wang, Kun, Fan, Kai, Feng, Zilong, Zhang, Yuxin, Zhao, Qianbin, Yun, Guolin, Yuan, Dan, Jiang, Lianmei, Li, Ming and Li, Weihua (2019). High-throughput, off-chip microdroplet generator enabled by a spinning conical frustum. Analytical Chemistry, 91 (5), 3725-3732. doi: 10.1021/acs.analchem.9b00093
Dean-flow-coupled elasto-inertial particle and cell focusing in symmetric serpentine microchannels
Yuan, Dan, Sluyter, Ronald, Zhao, Qianbin, Tang, Shiyang, Yan, Sheng, Yun, Guolin, Li, Ming, Zhang, Jun and Li, Weihua (2019). Dean-flow-coupled elasto-inertial particle and cell focusing in symmetric serpentine microchannels. Microfluidics and Nanofluidics, 23 (3) 41, 1-9. doi: 10.1007/s10404-019-2204-3
Functional liquid metal nanoparticles produced by liquid-based nebulization
Tang, Shi-Yang, Qiao, Ruirui, Lin, Yiliang, Li, Yuhuan, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Guo, Jinhong, Dickey, Michael D., Huang, Tony Jun, Davis, Thomas P., Kalantar-Zadeh, Kourosh and Li, Weihua (2019). Functional liquid metal nanoparticles produced by liquid-based nebulization. Advanced Materials Technologies, 4 (2) 1800420, 1-9. doi: 10.1002/admt.201800420
Zhao, Qianbin, Yuan, Dan, Tang, Shi-Yang, Yun, Guolin, Yan, Sheng, Zhang, Jun and Li, Weihua (2019). Top sheath flow-assisted secondary flow particle manipulation in microchannels with the slanted groove structure. Microfluidics and Nanofluidics, 23 (1) 6, 1-8. doi: 10.1007/s10404-018-2174-x
Tunable particle separation in a hybrid dielectrophoresis (DEP)- inertial microfluidic device
Zhang, Jun, Yuan, Dan, Zhao, Qianbin, Yan, Sheng, Tang, Shi-Yang, Tan, Say Hwa, Guo, Jinhong, Xia, Huanming, Nguyen, Nam-Trung and Li, Weihua (2018). Tunable particle separation in a hybrid dielectrophoresis (DEP)- inertial microfluidic device. Sensors and Actuators, B: Chemical, 267, 14-25. doi: 10.1016/j.snb.2018.04.020
Enhanced particle self-ordering in a double-layer channel
Yan, Sheng, Li, Yuxing, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Tang, Shi-Yang and Li, Weihua (2018). Enhanced particle self-ordering in a double-layer channel. Biomedical Microdevices, 20 (2) 23, 1-7. doi: 10.1007/s10544-018-0269-5
Yan, Sheng, Li, Yuxing, Zhu, Yuanqing, Liu, Minsu, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Zhang, Shiwu, Wen, Weijia, Tang, Shi-Yang and Li, Weihua (2018). Simple, low-cost fabrication of semi-circular channel using the surface tension of solder paste and its application to microfluidic valves. Electrophoresis, 39 (12), 1460-1465. doi: 10.1002/elps.201800064
Microfluidic mass production of stabilized and stealthy liquid metal nanoparticles
Tang, Shi-Yang, Qiao, Ruirui, Yan, Sheng, Yuan, Dan, Zhao, Qianbin, Yun, Guolin, Davis, Thomas P. and Li, Weihua (2018). Microfluidic mass production of stabilized and stealthy liquid metal nanoparticles. Small, 14 (21) 1800118, 1-8. doi: 10.1002/smll.201800118
Yan, Sheng, Zhu, Yuanqing, Tang, Shi-Yang, Li, Yuxing, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Zhang, Jun, Zhang, Shiwu and Li, Weihua (2018). A rapid, maskless 3D prototyping for fabrication of capillary circuits: toward urinary protein detection. Electrophoresis, 39 (7), 957-964. doi: 10.1002/elps.201700449
Yan, Sheng, Li, Yuxing, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Zhang, Jun, Wen, Weijia, Tang, Shi-Yang and Li, Weihua (2018). Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations. Lab on a Chip, 18 (5), 785-792. doi: 10.1039/c8lc00047f
Recent progress of particle migration in viscoelastic fluids
Yuan, Dan, Zhao, Qianbin, Yan, Sheng, Tang, Shi-Yang, Alici, Gursel, Zhang, Jun and Li, Weihua (2018). Recent progress of particle migration in viscoelastic fluids. Lab on a Chip, 18 (4), 551-567. doi: 10.1039/c7lc01076a
Versatile microfluidic platforms enabled by novel magnetorheological elastomer microactuators
Tang, Shi-Yang, Zhang, Xuchun, Sun, Shuaishuai, Yuan, Dan, Zhao, Qianbin, Yan, Sheng, Deng, Lei, Yun, Guolin, Zhang, Jun, Zhang, Shiwu and Li, Weihua (2018). Versatile microfluidic platforms enabled by novel magnetorheological elastomer microactuators. Advanced Functional Materials, 28 (8) 1705484, 1-10. doi: 10.1002/adfm.201705484
A portable, hand-powered microfluidic device for sorting of biological particles
Yan, Sheng, Tan, Say Hwa, Li, Yuxing, Tang, Shiyang, Teo, Adrian J. T., Zhang, Jun, Zhao, Qianbin, Yuan, Dan, Sluyter, Ronald, Nguyen, N. T. and Li, Weihua (2018). A portable, hand-powered microfluidic device for sorting of biological particles. Microfluidics and Nanofluidics, 22 (1) 8, 1-10. doi: 10.1007/s10404-017-2026-0
Zhao, Qianbin, Yan, Sheng, Yuan, Dan, Zhang, Jun, Du, Haiping, Alici, Gursel and Li, Weihua (2017). Double-mode microparticle manipulation by tunable secondary flow in microchannel with arc-shaped groove arrays. IEEE Transactions on Biomedical Circuits and Systems, 11 (6) 8010314, 1406-1412. doi: 10.1109/TBCAS.2017.2722012
High-throughput separation of white blood cells from whole blood using inertial microfluidics
Zhang, Jun, Yuan, Dan, Sluyter, Ronald, Yan, Sheng, Zhao, Qianbin, Xia, Huanming, Tan, Say Hwa, Nguyen, Nam-Trung and Li, Weihua (2017). High-throughput separation of white blood cells from whole blood using inertial microfluidics. IEEE Transactions on Biomedical Circuits and Systems, 11 (6) 8017537, 1422-1430. doi: 10.1109/TBCAS.2017.2735440
Yan, Sheng, Yuan, Dan, Zhao, Qianbin, Zhang, Jun and Li, Weihua (2017). The continuous concentration of particles and cancer cell line using cell margination in a groove-based channel. Micromachines, 8 (11) 315, 1-11. doi: 10.3390/mi8110315
On-chip microparticle and cell washing using coflow of viscoelastic fluid and Newtonian fluid
Yuan, Dan, Tan, Say Hwa, Sluyter, Ronald, Zhao, Qianbin, Yan, Sheng, Nguyen, N. T., Guo, Jinhong, Zhang, Jun and Li, Weihua (2017). On-chip microparticle and cell washing using coflow of viscoelastic fluid and Newtonian fluid. Analytical Chemistry, 89 (17), 9574-9582. doi: 10.1021/acs.analchem.7b02671
Analysis of hydrodynamic mechanism on particles focusing in micro-channel flows
Wang, Qikun, Yuan, Dan and Li, Weihua (2017). Analysis of hydrodynamic mechanism on particles focusing in micro-channel flows. Micromachines, 8 (7) 197, 1-11. doi: 10.3390/mi8070197
Zhang, Jun, Yan, Sheng, Yuan, Dan, Alici, Gursel, Nguyen, Nam-Trung and Li, Weihua (2017). High throughput cell-free extraction of plasma by an integrated microfluidic device combining inertial focusing and membrane. Journal of Heat Transfer, 139 (5) 052404, 1-7. doi: 10.1115/1.4035588
Zhao, Qianbin, Yuan, Dan, Yan, Sheng, Zhang, Jun, Du, Haiping, Alici, Gursel and Li, Weihua (2017). Flow rate-insensitive microparticle separation and filtration using a microchannel with arc-shaped groove arrays. Microfluidics and Nanofluidics, 21 (3) 55, 1-11. doi: 10.1007/s10404-017-1890-y
Zhao, Qianbin, Zhang, Jun, Yan, Sheng, Yuan, Dan, Du, Haiping, Alici, Gursel and Li, Weihua (2017). High-throughput sheathless and three-dimensional microparticle focusing using a microchannel with arc-shaped groove arrays. Scientific Reports, 7 (1) 41153, 1-11. doi: 10.1038/srep41153
Hybrid microfluidics combined with active and passive approaches for continuous cell separation
Yan, Sheng, Zhang, Jun, Yuan, Dan and Li, Weihua (2017). Hybrid microfluidics combined with active and passive approaches for continuous cell separation. Electrophoresis, 38 (2), 238-249. doi: 10.1002/elps.201600386
Sheathless Dean-flow-coupled elasto-inertial particle focusing and separation in viscoelastic fluid
Yuan, Dan, Tan, Say Hwa, Zhao, Qianbin, Yan, Sheng, Sluyter, Ronald, Nguyen, N. T., Zhang, Jun and Li, Weihua (2017). Sheathless Dean-flow-coupled elasto-inertial particle focusing and separation in viscoelastic fluid. RSC Advances, 7 (6), 3461-3469. doi: 10.1039/C6RA25328H
Huang, Qiangxian, Zhao, Yang, Yuan, Dan, Zhang, Liansheng and Cheng, Zhenying (2016). Characteristics of a dynamic atomic force microscopy based on a higher-order resonant silicon cantilever and experiments. Measurement: Journal of the International Measurement Confederation, 94, 31-36. doi: 10.1016/j.measurement.2016.07.081
Yan, S., Zhang, J., Yuan, D., Zhao, Q., Ma, J. and Li, W. H. (2016). High-throughput, sheathless, magnetophoretic separation of magnetic and non-magnetic particles with a groove-based channel. Applied Physics Letters, 109 (21) 214101, 214101. doi: 10.1063/1.4968835
Yuan, Dan, Pan, Chao, Zhang, Jun, Yan, Sheng, Zhao, Qianbin, Alici, Gursel and Li, Weihua (2016). Tunable particle focusing in a straight channel with symmetric semicircle obstacle arrays using electrophoresis-modified inertial effects. Micromachines, 7 (11) 195, 1-11. doi: 10.3390/mi7110195
Yan, Sheng, Zhang, Jun, Chen, Huaying, Yuan, Dan, Alici, Gursel, Du, Haiping, Zhu, Yonggang and Li, Weihua (2016). Development of a novel magnetophoresis-assisted hydrophoresis microdevice for rapid particle ordering. Biomedical Microdevices, 18 (4) 54, 1-9. doi: 10.1007/s10544-016-0078-7
Yuan, Dan, Zhang, Jun, Yan, Sheng, Peng, Gangrou, Zhao, Qianbin, Alici, Gursel, Du, Hejun and Li, Weihua (2016). Investigation of particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid. Electrophoresis, 37 (15-16), 2147-2155. doi: 10.1002/elps.201600102
Jin, Tiantian, Yan, Sheng, Zhang, Jun, Yuan, Dan, Huang, Xu-Feng and Li, Weihua (2016). A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform. Biomicrofluidics, 10 (3) 034104, 034104. doi: 10.1063/1.4949770
Zhang, Jun, Yan, Sheng, Yuan, Dan, Zhao, Qianbin, Tan, Say Hwa, Nguyen, Nam-Trung and Li, Weihua (2016). A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticles. Lab on a Chip, 16 (20), 3947-3956. doi: 10.1039/c6lc01007e
Yuan, Dan, Zhang, Jun, Sluyter, Ronald, Zhao, Qianbin, Yan, Sheng, Alici, Gursel and Li, Weihua (2016). Continuous plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion-contraction cavity arrays. Lab on a Chip, 16 (20), 3919-3928. doi: 10.1039/c6lc00843g
Fundamentals and applications of inertial microfluidics: a review
Zhang, Jun, Yan, Sheng, Yuan, Dan, Alici, Gursel, Nguyen, Nam-Trung, Ebrahimi Warkiani, Majid and Li, Weihua (2016). Fundamentals and applications of inertial microfluidics: a review. Lab on a Chip, 16 (1), 10-34. doi: 10.1039/c5lc01159k
Yan, Sheng, Zhang, Jun, Pan, Chao, Yuan, Dan, Alici, Gursel, Du, Haiping, Zhu, Yonggang and Li, Weihua (2015). An integrated dielectrophoresis-active hydrophoretic microchip for continuous particle filtration and separation. Journal of Micromechanics and Microengineering, 25 (8) 084010. doi: 10.1088/0960-1317/25/8/084010
Yuan, D., Zhang, J., Yan, S., Pan, C., Alici, G., Nguyen, N. T. and Li, W. H. (2015). Dean-flow-coupled elasto-inertial three-dimensional particle focusing under viscoelastic flow in a straight channel with asymmetrical expansion-contraction cavity arrays. Biomicrofluidics, 9 (4) 044108, 044108. doi: 10.1063/1.4927494
Huang, Qiang-Xian, You, Huan-Jie, Yuan, Dan, Zhao, Yang and Hu, Xiao-Juan (2014). High speed scanning for dynamic atomic force microscope based on higher-order resonance of silicon cantilever. Guangxue Jingmi Gongcheng/Optics and Precision Engineering, 22 (3), 656-663. doi: 10.3788/OPE.20142203.0656
Research and experiment on higher-order resonance characteristic of dynamic AFM cantilever
Huang, Qiangxian, Yuan, Dan, You, Huanjie, Zhao, Yang and Cheng, Zhenying (2013). Research and experiment on higher-order resonance characteristic of dynamic AFM cantilever. Yi Qi Yi Biao Xue Bao/Chinese Journal of Scientific Instrument, 34 (12), 2647-2652.
Huang, Qiangxian, Yuan, Dan and You, Huanjie (2012). Calibration and uncertainty estimation of one-dimensional reference grating using a metrological atomic force microscope. Zhongguo Jixie Gongcheng/China Mechanical Engineering, 23 (5), 531-536. doi: 10.3969/j.issn.1004-132X.2012.05.005
Portable and pumpless microfluidic device for viscoelastic particle focusing
Yuan, Dan, Nilghaz, Azadeh and Guijt, Rosanne M. (2022). Portable and pumpless microfluidic device for viscoelastic particle focusing. Chemical and Biological Microsystems Society.
Zhang, Jun, Yan, Sheng, Yuan, Dan, Alici, Gursel, Nguyen, Nam-Trung and Li, Weihua (2016). High throughput cell-free extraction of plasma by an integrated microfluidic device combining inertial microfluidics and membrane. ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer, Biopolis, Singapore, 4-6 January 2016. New York, NY USA: American Society of Mechanical Engineers. doi: 10.1115/MNHMT2016-6717
Yuan, D., Zhang, J., Yan, S., Pan, C., Alici, G., Nguyen, N. T. and Li, W. H. (2016). Three-dimensional particle focusing under viscoelastic flow based on dean-flow-coupled elasto-inertial effects. Seventh International Symposium on Precision Mechanical Measurements, Xia'men, China, 8-12 August 2015. Bellingham, WA USA: SPIE. doi: 10.1117/12.2211265
Characteristics of the higher-order resonant cantilever in dynamic atomic force microscopy
Zhao, Yang, Huang, Qiang-Xian, Yuan, Dan, You, Huan-Jie and Xie, Hong (2013). Characteristics of the higher-order resonant cantilever in dynamic atomic force microscopy. doi: 10.1117/12.2035924
Deciphering the mechanisms of object manipulation with viscoelastic fluids
(2024–2027) ARC Discovery Early Career Researcher Award
Development of object manipulation techniques with viscoelastic fluids toward efficient environmental monitoring
Doctor Philosophy — Principal Advisor
Other advisors:
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.
Viscoelastic Microfluidics for Biomedical and Environmental Applications
Project summary: Use forces generated by fluids that are both viscous and elastic to help address challenges in biomedicine and the environment.