My research aims to understand the processes generating and eliminating genetic variation, and the consequences of these processes for the adaptation and surival of species. When populations decline due to factors like habitat loss, selection becomes less effective at maintaining a healthy, robust population. The potential for "mutational meltdown" to drive extinction of populations in these circumstances, were selection is ineffective, has been noted for nearly a centuary. However, the way in which mutations change the traits that affect fitness, and can be removed by selection, remains quite mysterious. We work with native Australian rainforest flies, an amenable model for getting at these complex question. To extend our knowledge of how new mutations can contribute to adaptive potential in populations, we investiage how mutation changes traits ranging from body size to immune response. We use both direct correlations with fitness, and comparison between mutational and standing genetic variance to understand the selection acting on new mutations. We are particulary intereted in understanding the role that pleiotropy - where the same mutation affects more than one trait - might play in how quickly selection can improve fitness of a poulation. Whether changes to traits like size are beneficial or deleterious depends on the context. We therefore measure these mutational effects under different thermal and nutritional conditions to understand, for example, whether mutations that decrease fitness in the current environment might increase it under new environmental conditions. By understanding mutation, and the factors that affect it, our ultimate goal is to improve our predictions of if, and how, populations can adapt to novel environmental conditions.
Journal Article: Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata
Dugand, Robert J., Blows, Mark W. and McGuigan, Katrina (2023). Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 290 (1995) 20222111, 1-10. doi: 10.1098/rspb.2022.2111
Journal Article: Causes of variability in estimates of mutational variance from mutation accumulation experiments
Conradsen, Cara, Blows, Mark W and McGuigan, Katrina (2022). Causes of variability in estimates of mutational variance from mutation accumulation experiments. Genetics, 221 (2) iyac060, 1-14. doi: 10.1093/genetics/iyac060
Journal Article: The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata
Dugand, Robert J., Aguirre, J. David, Hine, Emma, Blows, Mark W. and McGuigan, Katrina (2021). The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. Proceedings of the National Academy of Sciences, 118 (31) e2026217118, 1-10. doi: 10.1073/pnas.2026217118
Journal Article: How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?
McGuigan, Katrina, Hoffmann, Ary A. and Sgrò, Carla M. (2021). How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1826) 20200119, 1-10. doi: 10.1098/rstb.2020.0119
Journal Article: Pleiotropic mutations are subject to strong stabilizing selection
McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). Pleiotropic mutations are subject to strong stabilizing selection. Genetics, 197 (3), 1051-1062. doi: 10.1534/genetics.114.165720
Journal Article: The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata
McGuigan, Katrina, Collet, Julie M., McGraw, Elizabeth A., Ye, Yixin H., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata. Genetics, 196 (3), 911-921. doi: 10.1534/genetics.114.161232
Journal Article: Joint allelic effects on fitness and metric traits
McGuigan, Katrina and Blows, Mark W. (2013). Joint allelic effects on fitness and metric traits. Evolution, 67 (4), 1131-1142. doi: 10.1111/j.1558-5646.2012.01833.x
Journal Article: Cryptic genetic variation and body size evolution in threespine stickleback
McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2011). Cryptic genetic variation and body size evolution in threespine stickleback. Evolution, 65 (4), 1203-1211. doi: 10.1111/j.1558-5646.2010.01195.x
Journal Article: Evolutionary consequences of cryptic genetic variation
McGuigan, K.L. and Sgro, C.M. (2009). Evolutionary consequences of cryptic genetic variation. Trends in Ecology & Evolution, 24 (6), 305-311. doi: 10.1016/j.tree.2009.02.001
Journal Article: Adaptation of rainbow fish to lake and stream habitats
McGuigan, Katrina, Franklin, Craig E., Moritz, Craig and Blows, Mark W. (2003). Adaptation of rainbow fish to lake and stream habitats. Evolution, 57 (1), 104-118. doi: 10.1554/0014-3820(2003)057[0104:AORFTL]2.0.CO;2
The nature of standing genetic variation
(2019–2023) ARC Discovery Projects
Understanding rapid adaptation to new environments
(2018–2021) ARC Discovery Projects
Understanding the fitness consequences of new mutations
(2016–2019) UQ Fellowships
The contribution of new mutations to genetic variation of quantitative traits
Doctor Philosophy
(2023) Doctor Philosophy
Context dependence of new mutations: the role of ancestral alleles and sex.
Doctor Philosophy
Dugand, Robert J., Blows, Mark W. and McGuigan, Katrina (2023). Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 290 (1995) 20222111, 1-10. doi: 10.1098/rspb.2022.2111
Causes of variability in estimates of mutational variance from mutation accumulation experiments
Conradsen, Cara, Blows, Mark W and McGuigan, Katrina (2022). Causes of variability in estimates of mutational variance from mutation accumulation experiments. Genetics, 221 (2) iyac060, 1-14. doi: 10.1093/genetics/iyac060
Dugand, Robert J., Aguirre, J. David, Hine, Emma, Blows, Mark W. and McGuigan, Katrina (2021). The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. Proceedings of the National Academy of Sciences, 118 (31) e2026217118, 1-10. doi: 10.1073/pnas.2026217118
How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?
McGuigan, Katrina, Hoffmann, Ary A. and Sgrò, Carla M. (2021). How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1826) 20200119, 1-10. doi: 10.1098/rstb.2020.0119
Pleiotropic mutations are subject to strong stabilizing selection
McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). Pleiotropic mutations are subject to strong stabilizing selection. Genetics, 197 (3), 1051-1062. doi: 10.1534/genetics.114.165720
The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata
McGuigan, Katrina, Collet, Julie M., McGraw, Elizabeth A., Ye, Yixin H., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata. Genetics, 196 (3), 911-921. doi: 10.1534/genetics.114.161232
Joint allelic effects on fitness and metric traits
McGuigan, Katrina and Blows, Mark W. (2013). Joint allelic effects on fitness and metric traits. Evolution, 67 (4), 1131-1142. doi: 10.1111/j.1558-5646.2012.01833.x
Cryptic genetic variation and body size evolution in threespine stickleback
McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2011). Cryptic genetic variation and body size evolution in threespine stickleback. Evolution, 65 (4), 1203-1211. doi: 10.1111/j.1558-5646.2010.01195.x
Evolutionary consequences of cryptic genetic variation
McGuigan, K.L. and Sgro, C.M. (2009). Evolutionary consequences of cryptic genetic variation. Trends in Ecology & Evolution, 24 (6), 305-311. doi: 10.1016/j.tree.2009.02.001
Adaptation of rainbow fish to lake and stream habitats
McGuigan, Katrina, Franklin, Craig E., Moritz, Craig and Blows, Mark W. (2003). Adaptation of rainbow fish to lake and stream habitats. Evolution, 57 (1), 104-118. doi: 10.1554/0014-3820(2003)057[0104:AORFTL]2.0.CO;2
Quantitative genetic variation, comparing patterns of
McGuigan, K. and Aguirre, J. D. (2016). Quantitative genetic variation, comparing patterns of. Encyclopedia of evolutionary biology. (pp. 377-387) edited by Richard M. Kliman. Kidlington, Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-800049-6.00045-7
Walter, Greg M and McGuigan, Katrina (2023). Predicting the future. eLife, 12 e91450. doi: 10.7554/elife.91450
Environmental dependence of mutational (co)variances of adaptive traits
Kannan, Ashvitha, Dugand, Robert J, Appleton, Nicholas C, Chenoweth, Stephen F, Sgrò, Carla M and McGuigan, Katrina (2023). Environmental dependence of mutational (co)variances of adaptive traits. Evolution. doi: 10.1093/evolut/qpad154
Moving beyond heritability in the search for coral adaptive potential
Richards, Thomas J., McGuigan, Katrina, Aguirre, J. David, Humanes, Adriana, Bozec, Yves‐Marie, Mumby, Peter J. and Riginos, Cynthia (2023). Moving beyond heritability in the search for coral adaptive potential. Global Change Biology, 29 (14), 3869-3882. doi: 10.1111/gcb.16719
Dugand, Robert J., Blows, Mark W. and McGuigan, Katrina (2023). Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 290 (1995) 20222111, 1-10. doi: 10.1098/rspb.2022.2111
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2022). Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species. Genetics, 222 (2) iyac122, 1-17. doi: 10.1093/genetics/iyac122
Causes of variability in estimates of mutational variance from mutation accumulation experiments
Conradsen, Cara, Blows, Mark W and McGuigan, Katrina (2022). Causes of variability in estimates of mutational variance from mutation accumulation experiments. Genetics, 221 (2) iyac060, 1-14. doi: 10.1093/genetics/iyac060
Dugand, Robert J., Aguirre, J. David, Hine, Emma, Blows, Mark W. and McGuigan, Katrina (2021). The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. Proceedings of the National Academy of Sciences, 118 (31) e2026217118, 1-10. doi: 10.1073/pnas.2026217118
Malard, Lucie, Riginos, Cynthia and McGuigan, Katrina (2021). Skeletal deformities and meristic trait variations are common in the intertidal fish Bathygobius cocosensis (Perciformes‐Gobiidae). Journal of Fish Diseases, 44 (6), 665-673. doi: 10.1111/jfd.13327
How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?
McGuigan, Katrina, Hoffmann, Ary A. and Sgrò, Carla M. (2021). How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1826) 20200119, 1-10. doi: 10.1098/rstb.2020.0119
Correlational selection in the age of genomics
Svensson, Erik I., Arnold, Stevan J., Bürger, Reinhard, Csilléry, Katalin, Draghi, Jeremy, Henshaw, Jonathan M., Jones, Adam G., De Lisle, Stephen, Marques, David A., McGuigan, Katrina, Simon, Monique N. and Runemark, Anna (2021). Correlational selection in the age of genomics. Nature Ecology and Evolution, 5 (5), 562-573. doi: 10.1038/s41559-021-01413-3
Thia, Joshua A., McGuigan, Katrina, Liggins, Libby, Figueira, Will F., Bird, Christopher E., Mather, Andrew, Evans, Jennifer L. and Riginos, Cynthia (2021). Genetic and phenotypic variation exhibit both predictable and stochastic patterns across an intertidal fish metapopulation. Molecular Ecology, 30 (18) mec.15829, 4392-4414. doi: 10.1111/mec.15829
Richards, Thomas J., Ortiz‐Barrientos, Daniel and McGuigan, Katrina (2019). Natural selection drives leaf divergence in experimental populations of Senecio lautus under natural conditions. Ecology and Evolution, 9 (12) ece3.5263, 6959-6967. doi: 10.1002/ece3.5263
Do slower movers have lower reproductive success and higher mutation load?
Walsh, Carly B. and McGuigan, Katrina (2018). Do slower movers have lower reproductive success and higher mutation load?. Evolution Letters, 2 (6), 590-598. doi: 10.1002/evl3.87
Hine, Emma, Runcie, Daniel E., McGuigan, Katrina and Blows, Mark W. (2018). Uneven distribution of mutational variance across the transcriptome of Drosophila serrata revealed by high-dimensional analysis of gene expression. Genetics, 209 (4), 1319-1328. doi: 10.1534/genetics.118.300757
Thia, Joshua A., Riginos, Cynthia, Liggins, Libby, Figueira, Will F. and McGuigan, Katrina (2018). Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish. The Journal of Animal Ecology, 87 (5), 1353-1363. doi: 10.1111/1365-2656.12844
Collet, Julie M., McGuigan, Katrina, Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2018). Mutational pleiotropy and the strength of stabilizing selection within and between functional modules of gene expression. Genetics, 208 (4), 1601-1616. doi: 10.1534/genetics.118.300776
How does mutation affect the distribution of phenotypes?
McGuigan, Katrina and Aw, Ernest (2017). How does mutation affect the distribution of phenotypes?. Evolution, 71 (10), 2445-2456. doi: 10.1111/evo.13358
Allen, Scott L., McGuigan, Katrina, Connallon, Tim, Blows, Mark W. and Chenoweth, Stephen F. (2017). Sexual selection on spontaneous mutations strengthens the between-sex genetic correlation for fitness. Evolution, 71 (10), 2398-2409. doi: 10.1111/evo.13310
Sztepanacz, Jacqueline L., McGuigan, Katrina and Blows, Mark W. (2017). Heritable micro-environmental variance covaries with fitness in an outbred population of Drosophila serrata. Genetics, 206 (4), 2185-2198. doi: 10.1534/genetics.116.199075
Repeatability of locomotor performance and morphology-locomotor performance relationships
Conradsen, Cara, Walker, Jeffrey A., Perna, Catherine and McGuigan, Katrina (2016). Repeatability of locomotor performance and morphology-locomotor performance relationships. Journal of Experimental Biology, 219 (18), 2888-2897. doi: 10.1242/jeb.141259
Richards, Thomas J., Walter, Greg M., McGuigan, Katrina and Ortiz-Barrientos, Daniel (2016). Divergent natural selection drives the evolution of reproductive isolation in an Australian wildflower. Evolution, 70 (9), 1993-2003. doi: 10.1111/evo.12994
Malard, Lucie A., McGuigan, Katrina and Riginos, Cynthia (2016). Site fidelity, size, and morphology may differ by tidal position for an intertidal fish, Bathygobius cocosensis (Perciformes-Gobiidae), in Eastern Australia. PeerJ, 2016 (7) e2263, e2263. doi: 10.7717/peerj.2263
Conradsen, C. and McGuigan, K. (2015). Sexually dimorphic morphology and swimming performance relationships in wild-type zebrafish Danio rerio. Journal of Fish Biology, 87 (5), 1219-1233. doi: 10.1111/jfb.12784
McGuigan, Katrina, David Aguirre, J. David and Blows, Mark W. (2015). Simultaneous estimation of additive and mutational genetic variance in an outbred population of drosophila serrata. Genetics, 201 (3), 1239-1251. doi: 10.1534/genetics.115.178632
Transcriptome-wide effects of sexual selection on the fate of new mutations
Collet, Julie M., Blows, Mark W. and McGuigan, Katrina (2015). Transcriptome-wide effects of sexual selection on the fate of new mutations. Evolution, 69 (11), 2905-2916. doi: 10.1111/evo.12778
The phenome-wide distribution of genetic variance
Blows, Mark W., Allen, Scott L., Collet, Julie M., Chenoweth, Stephen F. and McGuigan, Katrina (2015). The phenome-wide distribution of genetic variance. American Naturalist, 186 (1), 15-30. doi: 10.1086/681645
The distribution of genetic variance across phenotypic space and the response to selection
Blows, Mark W. and McGuigan, Katrina (2015). The distribution of genetic variance across phenotypic space and the response to selection. Molecular Ecology, 24 (9), 2056-2072. doi: 10.1111/mec.13023
Pleiotropic mutations are subject to strong stabilizing selection
McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). Pleiotropic mutations are subject to strong stabilizing selection. Genetics, 197 (3), 1051-1062. doi: 10.1534/genetics.114.165720
The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata
McGuigan, Katrina, Collet, Julie M., McGraw, Elizabeth A., Ye, Yixin H., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata. Genetics, 196 (3), 911-921. doi: 10.1534/genetics.114.161232
Comparing G: multivariate analysis of genetic variation in multiple populations
Aguirre, J. D., Hine, E., McGuigan, K. and Blows, M. W. (2014). Comparing G: multivariate analysis of genetic variation in multiple populations. Heredity, 112 (1), 21-29. doi: 10.1038/hdy.2013.12
Evolutionary constraints in high-dimensional trait sets
Hine, Emma, McGuigan, Katrina and Blows, Mark W. (2014). Evolutionary constraints in high-dimensional trait sets. American Naturalist, 184 (1), 119-131. doi: 10.1086/676504
Latimer, Camille A. L., McGuigan, Katrina, Wilson, Robbie S., Blows, Mark W. and Chenoweth, Stephen F. (2014). The contribution of spontaneous mutations to thermal sensitivity curve variation in drosophila serrata. Evolution, 68 (6), 1824-1837. doi: 10.1111/evo.12392
Joint allelic effects on fitness and metric traits
McGuigan, Katrina and Blows, Mark W. (2013). Joint allelic effects on fitness and metric traits. Evolution, 67 (4), 1131-1142. doi: 10.1111/j.1558-5646.2012.01833.x
Kimmel, Charles B., Cresko, William A., Phillips, Patrick C., Ullmann, Bonnie, Currey, Mark, von Hippel, Frank, Kristjansson, Bjarni K., Gelmond, Ofer and McGuigan, Katrina (2012). Independent axes of genetic variation and parallel evolutionary divergence of opercle bone shape in threespine stickleback. Evolution, 66 (2), 419-434. doi: 10.1111/j.1558-5646.2011.01441.x
Reducing mutation load through sexual selection on males
McGuigan, Kate, Petfield, Donna and Blows, Mark W. (2011). Reducing mutation load through sexual selection on males. Evolution, 65 (10), 2816-2829. doi: 10.1111/j.1558-5646.2011.01346.x
Cryptic genetic variation and body size evolution in threespine stickleback
McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2011). Cryptic genetic variation and body size evolution in threespine stickleback. Evolution, 65 (4), 1203-1211. doi: 10.1111/j.1558-5646.2010.01195.x
Natural selection stops the evolution of male attractiveness
Hine, Emma, McGuigan, Katrina and Blows, Mark W (2011). Natural selection stops the evolution of male attractiveness. Proceedings of the National Academy of Sciences of the United States of America, 108 (9), 3659-3664. doi: 10.1073/pnas.1011876108
Pleiotropy, apparent stabilizing selection and uncovering fitness optima
McGuigan, Katrina, Rowe, Locke and Blows, Mark W. (2011). Pleiotropy, apparent stabilizing selection and uncovering fitness optima. Trends In Ecology & Evolution, 26 (1), 22-29. doi: 10.1016/j.tree.2010.10.008
The genetic basis of sexually selected variation
Chenoweth, Stephen F. and McGuigan, Katrina (2010). The genetic basis of sexually selected variation. Annual Review of Ecology Evolution and Systematics, 41, 81-101. doi: 10.1146/annurev-ecolsys-102209-144657
McGuigan, Katrina and Blows, Mark W. (2010). Evolvability of individual traits in a multivariate context: Partitioning the additive genetic variance into common and specific components. Evolution, 64 (7), 1899-1911. doi: 10.1111/j.1558-5646.2010.00968.x
Asymmetry of genetic variation in fitness-related traits: Apparent stabilizing selection on g(max)
McGuigan, Katrina and Blows, Mark W. (2009). Asymmetry of genetic variation in fitness-related traits: Apparent stabilizing selection on g(max). Evolution, 63 (11), 2838-2847. doi: 10.1111/j.1558-5646.2009.00759.x
Condition dependence varies with mating success in male Drosophila bunnanda
McGuigan, K (2009). Condition dependence varies with mating success in male Drosophila bunnanda. JOURNAL OF EVOLUTIONARY BIOLOGY, 22 (9), 1813-1825. doi: 10.1111/j.1420-9101.2009.01791.x
Evolutionary consequences of cryptic genetic variation
McGuigan, K.L. and Sgro, C.M. (2009). Evolutionary consequences of cryptic genetic variation. Trends in Ecology & Evolution, 24 (6), 305-311. doi: 10.1016/j.tree.2009.02.001
An Evolutionary Limit to Male Mating Success
McGuigan, K. L., Van Homrigh, A. J. and Blows, M. W. (2008). An Evolutionary Limit to Male Mating Success. Evolution, 62 (6), 1528-1537. doi: 10.1111/j.1558-5646.2008.00379.x
Genetic Analysis of Female Preference Functions as Function-Valued Traits
McGuigan, K. L., Van Homrigh, A.J. and Blows, M. W. (2008). Genetic Analysis of Female Preference Functions as Function-Valued Traits. American Naturalist, 172 (2), 194-202. doi: 10.1086/588075
Studies of threespine stickleback developmental evolution: Progress and promise
Cresko, W. A., McGuigan, K. L., Phillips, P. C. and Postlethwait, J. H. (2007). Studies of threespine stickleback developmental evolution: Progress and promise. Genetica, 129 (1), 105-126. doi: 10.1007/s10709-006-0036-z
The depletion of genetic variance by sexual selection
Van Homrigh, A., Higgie, M., McGuigan, K. and Blows, M. W. (2007). The depletion of genetic variance by sexual selection. Current Biology, 17 (6), 528-532. doi: 10.1016/j.cub.2007.01.055
The phenotypic and genetic covariance structure of drosphilid wings
McGuigan, K. and Blows, M. W. (2007). The phenotypic and genetic covariance structure of drosphilid wings. Evolution, 61 (4), 902-911. doi: 10.1111/j.1558-5646.2007.00078.x
Studying phenotypic evolution using multivariate quantitative genetics
McGuigan, K. L. (2006). Studying phenotypic evolution using multivariate quantitative genetics. Molecular Ecology, 15 (4), 883-896. doi: 10.1111/j.1365-294X.2006.02809.x
Phenotypic divergence along lines of genetic variance
McGuigan, K., Chenoweth, S. F. and Blows, M. W. (2005). Phenotypic divergence along lines of genetic variance. American Naturalist, 165 (1), 32-43. doi: 10.1086/426600
Evolution of sarcomeric myosin heavy chain genes: Evidence from fish
McGuigan, K., Phillips, P. C. and Postlethwait, J. H. (2004). Evolution of sarcomeric myosin heavy chain genes: Evidence from fish. Molecular Biology And Evolution, 21 (6), 1042-1056. doi: 10.1093/molbev/msh103
Adaptation of rainbow fish to lake and stream habitats
McGuigan, Katrina, Franklin, Craig E., Moritz, Craig and Blows, Mark W. (2003). Adaptation of rainbow fish to lake and stream habitats. Evolution, 57 (1), 104-118. doi: 10.1554/0014-3820(2003)057[0104:AORFTL]2.0.CO;2
An addition to the rainbowfish (Melanotaeniidae) fauna of North Queensland
McGuigan, Katrina Louise (2001). An addition to the rainbowfish (Melanotaeniidae) fauna of North Queensland. Memoirs of the Queensland Museum, 46 (2), 647-655.
An addition to the rainbowfish (Melanotaeniidae) fauna of North Queensland
McGuigan, K. L. (2001). An addition to the rainbowfish (Melanotaeniidae) fauna of North Queensland. Memoirs of the Queensland Museum, 46 (2), 647-656.
Mcguigan, K., Zhu, D., Allen, G. R. and Moritz, C. C. (2000). Phylogenetic relationships and historical biogeography of melanotaenlid fishes in Australia and New Guinea. Marine Freshwater Research, 51 (7), 713-723. doi: 10.1071/MF99159
Donnellan, S. C., McGuigan, K., Knowles, R., Mahony, M. and Moritz, C. C. (1999). Genetic evidence for species boundaries in frogs of the Litoria citropa species-group (Anura: Hylidae). Australian Journal of Zoology, 47 (3), 275-293. doi: 10.1071/ZO99013
McGuigan, K, McDonald, K, Parris, K and Moritz, C (1998). Mitochondrial DNA diversity and historical biogeography of a wet forest-restricted frog (Litoria pearsoniana) from mid-east Australia. Molecular Ecology, 7 (2), 175-186. doi: 10.1046/j.1365-294x.1998.00329.x
Quantitative genetic variation in static allometry in the threespine stickleback
McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2010). Quantitative genetic variation in static allometry in the threespine stickleback. Annual Meeting of the Society for Integrative and Comparative Biology (SICB 2010), Seattle, United States, 3-7 January 2010. McLean, VA, United States: Society for Integrative and Comparative Biology. doi: 10.1093/icb/icq026
McGuigan, Katrina and Dugand, Robert (2023). MxE_Drosophila serrata. The University of Queensland. (Dataset) doi: 10.48610/01993ca
Hine, Emma, Runcie, Daniel E. , Allen, Scott L. , Wang, Yiguan , Chenoweth, Stephen F. , Blows, Mark W. and McGuigan, Katrina (2021). R code and input files required to generate figures and tables for BSFG analysis of standing variance in two Drosophila datasets. This dataset is the current version and supercedes any earlier versions.. The University of Queensland. (Dataset) doi: 10.48610/a3c5652
Enrichment analysis results for heritable common factors of Drosophila gene expression
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2021). Enrichment analysis results for heritable common factors of Drosophila gene expression. The University of Queensland. (Dataset) doi: 10.48610/90441fc
R code used to implement Bayesian sparse factor genetic analysis of Drosophila gene expression.
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2021). R code used to implement Bayesian sparse factor genetic analysis of Drosophila gene expression.. The University of Queensland. (Dataset) doi: 10.48610/ec9b92c
Hine, Emma , Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F. , Blows, Mark W. and McGuigan, Katrina (2021). Two Drosophila datasets used in the Bayesian sparse factor analysis of standing genetic variance in 3385 gene expression traits. The University of Queensland. (Dataset) doi: 10.48610/f3eede4
R code used to simulate directional selection on a moderately heritable polygenic phenotype
Oliveros Sandino, Alejandro , McGuigan, Katrina and Hine, Emma (2020). R code used to simulate directional selection on a moderately heritable polygenic phenotype. The University of Queensland. (Dataset) doi: 10.14264/701bad9
Evolutionary genetics of rainbowfish : phylogeny, adaptation and constraint
McGuigan, Katrina Louise. (2001). Evolutionary genetics of rainbowfish : phylogeny, adaptation and constraint. PhD Thesis, School of Biological Sciences, The University of Queensland.
The nature of standing genetic variation
(2019–2023) ARC Discovery Projects
Understanding rapid adaptation to new environments
(2018–2021) ARC Discovery Projects
Understanding the fitness consequences of new mutations
(2016–2019) UQ Fellowships
The contribution of pleiotropic mutation to genetic variation and evolution
(2015–2017) ARC Discovery Projects
Understanding phenotypes: Contributions from studying mutations in a model organism
(2012–2016) ARC Future Fellowships
Multivariate Quantitative Genetics And The Lek Paradox
(2005–2007) ARC Discovery Projects
The contribution of new mutations to genetic variation of quantitative traits
Doctor Philosophy — Principal Advisor
Other advisors:
Context dependence of new mutations: the role of ancestral alleles and sex.
Doctor Philosophy — Principal Advisor
Other advisors:
Some like it hot: invasive species, hybridisation, and a warming world
Doctor Philosophy — Associate Advisor
Other advisors:
The relationships between dietary macronutrients and ageing
Doctor Philosophy — Associate Advisor
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(2023) Doctor Philosophy — Principal Advisor
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The impacts of mutation and selection on sex-biased gene expression in Drosophila serrata
(2021) Master Philosophy — Associate Advisor
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Seeing and responding to colour signals: an investigation using coral reef fish
(2020) Doctor Philosophy — Associate Advisor
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(2019) Doctor Philosophy — Associate Advisor
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Response to natural selection in Senecio Lautus
(2017) Doctor Philosophy — Associate Advisor
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(2016) Doctor Philosophy — Associate Advisor
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(2010) Doctor Philosophy — Associate Advisor
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