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Reaching new heights in high-resolution electron microscopy (2015–2016)

Abstract:
Direct Electron Detection cameras are a recent technological breakthrough delivering one of the greatest single advancements to the field of molecular cryo-EM. The aim of this proposal is to enable a "first of a kind" cryo-EM platform in Australia enabling high-throughput atomic resolution protein structure determination. This will be achieved by integrating a state-of-the-art Gatan K2 Summit Direct Electron Detection camera system into the established ~$15M cryo-EM facility managed by the UQ node of the Australian Microscopy & Microanalysis Facility. This will offer unique and significantly improved capabilities for atomic resolution protein structure analysis, and will support a broad range of projects across the biological sciences.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:

  • Professor Ben Hankamer

    Professorial Research Fellow
    Institute for Molecular Bioscience

  • Associate Professor Michael Landsberg

    Associate Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Professor Robert Parton

    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine

  • Professor Paul Young

    Professor, Research Development
    Office of the Deputy Vice-Chancellor (Research and Innovation)
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology

  • Professor Michael Monteiro

    Senior Group Leader
    Australian Institute for Bioengineering and Nanotechnology
    Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council