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Single molecule sensing on nanopillars: Reading complex molecular circuits (2021–2023)

Abstract:
This project aims to develop an entirely new nanotechnology to visualise dynamic molecular circuits in real time, and within any biological sample as small as a single cell. This project expects to generate new knowledge in the field of cell biology and sensor technology, using innovative nanofabrication and nanoscopic fluid flows to advance understanding of the emerging field of single protein molecule interactions in cellular pathways. Expected outcomes include a universal technology platform to detect single molecules in single cells, with potential to deliver valuable intellectual property of commercial interest and economic benefit through technological advancements.
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Matt Trau

    ARC Australian Laureate Fellow
    Australian Institute for Bioengineering and Nanotechnology
    ARC Laureate Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Dr Alain Wuethrich

    NHMRC Emerging Leadership Fellow
    Australian Institute for Bioengineering and Nanotechnology

  • Dr Abu Sina

    NHMRC Emerging Leadership Fellow
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
Australian Research Council