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Employment
Journal Article: Induced pluripotent stem cells from a marsupial, the Tasmanian devil (Sarcophilus harrisii): insight into the evolution of mammalian pluripotency
Weeratunga, Prasanna, Shahsavari, Arash, Ovchinnikov, Dmitry A., Wolvetang, Ernst J. and Whitworth, Deanne J. (2018) Induced pluripotent stem cells from a marsupial, the Tasmanian devil (Sarcophilus harrisii): insight into the evolution of mammalian pluripotency. Stem Cells and Development, 27 2: 112-122. doi:10.1089/scd.2017.0224
Journal Article: The X factor: X chromosome dosage compensation in the evolutionarily divergent monotremes and marsupials
Whitworth, Deanne J. and Pask, Andrew J. (2016) The X factor: X chromosome dosage compensation in the evolutionarily divergent monotremes and marsupials. Seminars in Cell and Developmental Biology, 56 117-121. doi:10.1016/j.semcdb.2016.01.006
Journal Article: Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment
Burkard, Michael, Whitworth, Deanne, Schirmer, Kristin and Nash, Susan B. (2015) Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment. Aquatic Toxicology, 167 240-247. doi:10.1016/j.aquatox.2015.08.005
Journal Article: Stem cell therapies for treating osteoarthritis: prescient or premature?
Whitworth, Deanne J. and Banks, Tania A. (2014) Stem cell therapies for treating osteoarthritis: prescient or premature?. The Veterinary Journal, 202 3: 416-424. doi:10.1016/j.tvjl.2014.09.024
Journal Article: Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro
Ovchinnikov, Dmitry A., Titmarsh, Drew M., Fortuna, Patrick R. J., Hidalgo, Alejandro, Alharbi, Samah, Whitworth, Deanne J., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro. Stem Cell Research, 13 2: 251-261. doi:10.1016/j.scr.2014.05.006
Journal Article: Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFbeta/activin signaling pathway
Whitworth, Deanne J., Frith, Jessica E, Frith, Thomas J. R., Ovchinnikov, Dmitry A., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFbeta/activin signaling pathway. Stem Cells and Development, Online Ahead of Print . doi:10.1089/scd.2013.0634
Journal Article: Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts
Whitworth, Deanne J., Ovchinnikov, Dmitry A., Sun, Jane, Fortuna, Patrick R. J. and Wolvetang, Ernst J. (2014) Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, Fast Track Articles 13: 1-9. doi:10.1089/scd.2013.0461
Journal Article: Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts
Whitworth, Deanne J., Ovchinnikov, Dmitry A. and Wolvetang, Ernst J. (2012) Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, 21 12: 2288-2297. doi:10.1089/scd.2011.0608
(2018–2020) Morris Animal Foundation
(2017–2018) Annandale Bequest
(2015–2016) Research Donation Generic
A stem cell based approach to the treatment of devil facial disease in the Tasmanian Devil (Sarcophilus harrisli)
Doctor Philosophy
A pre-clinical trial using in vitro-derived mesenchymal stem cells to effect cartilage repair in a canine model of osteoarthritis
Doctor Philosophy
Improving efficiency of embryo technologies to expedite livestock genetic gain
Doctor Philosophy
Weeratunga, Prasanna, Shahsavari, Arash, Ovchinnikov, Dmitry A., Wolvetang, Ernst J. and Whitworth, Deanne J. (2018) Induced pluripotent stem cells from a marsupial, the Tasmanian devil (Sarcophilus harrisii): insight into the evolution of mammalian pluripotency. Stem Cells and Development, 27 2: 112-122. doi:10.1089/scd.2017.0224
Whitworth, Deanne J. and Pask, Andrew J. (2016) The X factor: X chromosome dosage compensation in the evolutionarily divergent monotremes and marsupials. Seminars in Cell and Developmental Biology, 56 117-121. doi:10.1016/j.semcdb.2016.01.006
Burkard, Michael, Whitworth, Deanne, Schirmer, Kristin and Nash, Susan B. (2015) Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment. Aquatic Toxicology, 167 240-247. doi:10.1016/j.aquatox.2015.08.005
Stem cell therapies for treating osteoarthritis: prescient or premature?
Whitworth, Deanne J. and Banks, Tania A. (2014) Stem cell therapies for treating osteoarthritis: prescient or premature?. The Veterinary Journal, 202 3: 416-424. doi:10.1016/j.tvjl.2014.09.024
Ovchinnikov, Dmitry A., Titmarsh, Drew M., Fortuna, Patrick R. J., Hidalgo, Alejandro, Alharbi, Samah, Whitworth, Deanne J., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro. Stem Cell Research, 13 2: 251-261. doi:10.1016/j.scr.2014.05.006
Whitworth, Deanne J., Frith, Jessica E, Frith, Thomas J. R., Ovchinnikov, Dmitry A., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFbeta/activin signaling pathway. Stem Cells and Development, Online Ahead of Print . doi:10.1089/scd.2013.0634
Whitworth, Deanne J., Ovchinnikov, Dmitry A., Sun, Jane, Fortuna, Patrick R. J. and Wolvetang, Ernst J. (2014) Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, Fast Track Articles 13: 1-9. doi:10.1089/scd.2013.0461
Whitworth, Deanne J., Ovchinnikov, Dmitry A. and Wolvetang, Ernst J. (2012) Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, 21 12: 2288-2297. doi:10.1089/scd.2011.0608
The transgenic mouse in studies of mammalian sexual differentiation.
Whitworth, Deanne J. and Behringer, Richard R. (2001). The transgenic mouse in studies of mammalian sexual differentiation.. In Martin M. Matzuk, Chester W. Brown, T. Rajendra Kumar and P. Michael Conn (Ed.), Transgenics in Endocrinology (pp. 19-39) Totowa, NJ, U.S.A.: Humana Press.
Sexual determination and differentiation in the marsupial Macropus eugenii
Shaw, Geoffrey, Harry, Jenny L., Whitworth, Deanne J. and Renfree, Marilyn B. (1997). Sexual determination and differentiation in the marsupial Macropus eugenii. In N. R. Saunders and L. A. Hinds (Ed.), Marsupial biology : Recent research, new perspectives (pp. 132-141) Sydney, NSW, Australia: University of NSW Press.
Fortuna, Patrick R. J., Bielefeldt-Ohmann, Helle, Ovchinnikov, Dmitry A., Wolvetang, Ernst Jurgen and Whitworth, Deanne Jeanette (2018) Cortical neurons derived from equine induced pluripotent stem cells are susceptible to neurotropic flavivirus infection and replication: an in vitro model for equine neuropathic diseases. Stem cells and development, . doi:10.1089/scd.2017.0106
Weeratunga, Prasanna, Shahsavari, Arash, Ovchinnikov, Dmitry A., Wolvetang, Ernst J. and Whitworth, Deanne J. (2018) Induced pluripotent stem cells from a marsupial, the Tasmanian devil (Sarcophilus harrisii): insight into the evolution of mammalian pluripotency. Stem Cells and Development, 27 2: 112-122. doi:10.1089/scd.2017.0224
Whitworth, Deanne J. and Pask, Andrew J. (2016) The X factor: X chromosome dosage compensation in the evolutionarily divergent monotremes and marsupials. Seminars in Cell and Developmental Biology, 56 117-121. doi:10.1016/j.semcdb.2016.01.006
Burkard, Michael, Whitworth, Deanne, Schirmer, Kristin and Nash, Susan B. (2015) Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment. Aquatic Toxicology, 167 240-247. doi:10.1016/j.aquatox.2015.08.005
Stem cell therapies for treating osteoarthritis: prescient or premature?
Whitworth, Deanne J. and Banks, Tania A. (2014) Stem cell therapies for treating osteoarthritis: prescient or premature?. The Veterinary Journal, 202 3: 416-424. doi:10.1016/j.tvjl.2014.09.024
Ovchinnikov, Dmitry A., Titmarsh, Drew M., Fortuna, Patrick R. J., Hidalgo, Alejandro, Alharbi, Samah, Whitworth, Deanne J., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro. Stem Cell Research, 13 2: 251-261. doi:10.1016/j.scr.2014.05.006
Whitworth, Deanne J., Frith, Jessica E, Frith, Thomas J. R., Ovchinnikov, Dmitry A., Cooper-White, Justin J. and Wolvetang, Ernst J. (2014) Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFbeta/activin signaling pathway. Stem Cells and Development, Online Ahead of Print . doi:10.1089/scd.2013.0634
Whitworth, Deanne J., Ovchinnikov, Dmitry A., Sun, Jane, Fortuna, Patrick R. J. and Wolvetang, Ernst J. (2014) Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, Fast Track Articles 13: 1-9. doi:10.1089/scd.2013.0461
Whitworth, Deanne J., Ovchinnikov, Dmitry A. and Wolvetang, Ernst J. (2012) Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells and Development, 21 12: 2288-2297. doi:10.1089/scd.2011.0608
Overtraining syndrome in horses
McGowan, C. M. and Whitworth, D. J. (2008) Overtraining syndrome in horses. Comparative Exercise Physiology, 5 2: 57-65. doi:10.1017/S1478061508979202
Marsupial anti-Mullerian hormone gene structure, regulatory elements, and expression
Pask, Andrew J., Whitworth, Deanne, J., Mao Chai-An, Wei, Kei-Jun, Sankovic, Natasha, Graves, Jennifer A. M., Shaw, Geoffrey, Renfree, Marilyn B. and Behringer, Richard R. (2004) Marsupial anti-Mullerian hormone gene structure, regulatory elements, and expression. Biology of Reproduction, 70 1: 160-167. doi:10.1095/biolreprod.103.020016
Characterization of steroidogenic factor 1 during sexual differentiation in a marsupial
Whitworth, D. J., Pask, A. J., Shaw, G., Marshall Graves, J. A., Behringer, R. R. and Renfree, M. B. (2001) Characterization of steroidogenic factor 1 during sexual differentiation in a marsupial. Gene, 277 1-2: 209-219. doi:10.1016/S0378-1119(01)00677-1
Bi, Weimin, Huang, Wendong, Whitworth, Deanne J., Deng, Jian Min, Zhang, Zhaoping, Behringer, Richard R. and de Crombrugghe, Benoit (2001) Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proceedings of the National Academy of Sciences of the United States of America, 98 12: 6698-6703. doi:10.1073/pnas.111092198
A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse
Bishop, Colin E., Whitworth, Deanne J., Qin, Yanjun, Agoulnik, Alexander I., Agoulnik, Irina A., Harrison, Wilbur R., Behringer, Richard R. and Overbeek, Paul A. (2000) A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse. Nature Genetics, 26 4: 490-494. doi:10.1038/82652
Whitworth, Deanne J., Hunt, Leigh and Licht, Paul (2000) Widespread expression of the mRNA encoding a novel vitamin D/thyroxine dual binding protein in the turtle Trachemys scripta. General and Comparative Endocrinology, 118 2: 354-358.
High specificity of Müllerian-inhibiting substance signaling in vivo
Mishina, Y., Whitworth, D. J., Racine, C. and Behringer, R. R.. (1999) High specificity of Müllerian-inhibiting substance signaling in vivo. Endocrinology, 140 5: 2084-2088. doi:10.1210/en.140.5.2084
Testis-like steroidogenesis in the ovotestis of the European mole, Talpa europaea
Whitworth, Deanne J., Licht, Paul, Racey, Paul A. and Glickman, Stephen E. (1999) Testis-like steroidogenesis in the ovotestis of the European mole, Talpa europaea. Biology of Reproduction, 60 2: 413-418. doi:10.1095/biolreprod60.2.413
XX germ cells: The difference between an ovary and a testis
Whitworth, Deanne J. (1998) XX germ cells: The difference between an ovary and a testis. Trends in Endocrinology and Metabolism, 9 1: 2-6. doi:10.1016/S1043-2760(98)00002-2
Müllerian duct regression in a marsupial, the tammar wallaby
Whitworth, Deanne J., Shaw, Geoffrey and Renfree Marilyn B. (1997) Müllerian duct regression in a marsupial, the tammar wallaby. Anatomy And Embryology, 196 1: 39-46. doi:10.1007/s004290050078
Gonadal sex reversal of the developing marsupial ovary in vivo and in vitro
Whitworth, Deanne J., Shaw, Geoffrey and Renfree, Marilyn B. (1996) Gonadal sex reversal of the developing marsupial ovary in vivo and in vitro. Development (Cambridge), 122 12: 4057-4063.
Shahsavari, A., Ovchinnikov, D., Wolvetang, E. and Whitworth, D. (2018). IMMUNOMODULATORY AND ANTI-INFLAMMATORY CAPABILITIES OF CANINE MESENCHYMAL STEM CELLS AND THEIR CLINICAL POTENTIAL. In: Joint 10th Annual Scientific Meeting of the Australian-Gene-and-Cell-Therapy-Society (AGCTS) and Australasian-Society-for-Stem-Cell-Research (ASSCR), Sydney Australia, (). May 24-26, 2017.
Weeratunga, Prasanna, Shahsavari, Arash, Ovchinnikov, Dmitry, Wolvetang, Ernst and Whitworth, Deanne (2018). INDUCED PLURIPOTENT STEM CELLS FROM A MARSUPIAL, THE TASMANIAN DEVIL (SARCOPHILUS HARRISII): INSIGHT INTO THE EVOLUTION OF MAMMALIAN PLURIPOTENCY. In: Joint 10th Annual Scientific Meeting of the Australian-Gene-and-Cell-Therapy-Society (AGCTS) and Australasian-Society-for-Stem-Cell-Research (ASSCR), Sydney Australia, (). May 24-26, 2017.
Whitworth, D. J., Gauthier, M.-E., Ovchinnikov, D. A., Grimmond, S. M., Marshall Graves, J. A. and Wolvetang, E. J. (2015). Platypus Induced Pluripotent Stem Cells Reveal that Acquisition of SOX2 Responsiveness Facilitated Expansion of the Pluripotency Network During Mammalian Evolution. In: Annual Meeting of the International Society for Stem Cell Research, Stockholm , Sweden, (). 24-27 June 2015.
Stem cell therapies for treating osteoarthritis: prescient or premature?
Whitworth, Deanne (2015). Stem cell therapies for treating osteoarthritis: prescient or premature?. In: Australian and New Zealand College of Veterinary Scientists College Science Week Conference, Gold Coast, QLD, Australia, (). 9-11 July 2015.
Whitworth, Deanne J., Ovchinnikov, Dmitry A., Sun, Jane, Fortuna, Patrick R. J. and Wolvetang, Ernst J. (2013). FGF/ERK signalling induces X chromosome inactivation in LIF-dependent equine induced pluripotent stem cells. In: ASSCR 2013: 6th Annual Meeting for Australasian Society for Stem Cell Research, South Bank, QLD, Australia, (). 27-29 October, 2013.
Whitworth, D. J., Sun, J and Wolvetang, E. J. (2012). The generation of induced pluripotent stem cells from human CD34+ cells reveals a sex bias in reprogramming efficiency. In: Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, (). 13-16 June 2012.
Sox9 and Sertoli cell differentiation in the mouse
Whitworth, D. J., Bi, W., Deng, J. M., de Crombrugghe, B. and Behringer, R. R. (2000). Sox9 and Sertoli cell differentiation in the mouse. In: Proceedings of the Second International Symposium on the Biology of Vertebrate Sex Determination. Second International Symposium on the Biology of Vertebrate Sex Determination, Hawaii, U.S.A., (87). xx.
An analysis of the behaviour of Sox9 mutant cells in testicular development
Whitworth, D. J., Bi, W., Deng, J. M., de Crombrugghe, B. and Behringer, R. R. (1998). An analysis of the behaviour of Sox9 mutant cells in testicular development. In: Proceedings of the Cold Spring Harbor Meeting on Mouse Molecular Genetics. Cold Spring Harbor Meeting on Mouse Molecular Genetics, Cold Spring Harbor Laboratory, New York, (288). xx.
Testis-like steroidogenesis in the ovotestis of the European mole
Whitworth, Deanne, Licht, .P, Racey, P. A. and Glickman, S. E. (1998). Testis-like steroidogenesis in the ovotestis of the European mole. In: Society for the Study of Reproduction, Ann Arbor, MI, (213-213). xx.
Sexual differentiation in marsupial mammals
Renfree, Marilyn B., Shaw, Geoffrey, Harry, Jenny L. and Whitworth, Deanne J. (1995). Sexual differentiation in marsupial mammals. In: Keystone Symposia on Molecular & Cellullar Biology. Keystone Symposium on the Molecular Basis for the Differences Between the Sexes, Tamarron, CO, U.S.A., (41-41). 12-18 February 1995.
Gonadal sex reversal in female tammar wallabies is induced by MIS
Whitworth, D. J. and Renfree, M. B. (1994). Gonadal sex reversal in female tammar wallabies is induced by MIS. In: Proceedings of the 23th Annual Conference of the Australian Society for Reproductive Biology. Australian Society for Reproductive Biology and the Endocrine Society of Australia Annual Scientific Meeting, Sydney, NSW, Australia, (100). 30 September-2 October 1991.
Whitworth, D. J., Harry, J. L., Shaw, G. and Renfree, M. B. (1994). Müllerian inhibiting substance gene expression in the developing gonad of the tammar wallaby (Macropus eugenii). In: Society for the Study of Reproduction and Fertility, Southhampton, UK, (52-52). xx.
Whitworth, Deanne, Harry, J. L., Shaw, G. and Renfree, M. B. (1994). Müllerian inhibiting substance gene expression in the developing testis of the tammar wallaby (Macropus eugenii). In: Proceedings of the Australian Society for Reproductive Biology. Australian Society for Reproductive Biology, Sydney , Australia, (68). xx.
Whitworth, D. J. and McLean, J. R. (1992). Density of adrenergic nerves about guinea-pig intrapulmonary arterial smooth muscle increases with decreasing vessel diameter. In: Communications of the Fifty-fifth Meeting of the Society at the University of Melbourne. The 55th Meeting of the Australian Physiological and Pharmacological Society jointly with the Australian and New Zealand Society of Neplanology, Melbourne, VIC, Australia, (78-78). 27-28 February 1992.
(2018–2020) Morris Animal Foundation
(2017–2018) Annandale Bequest
(2015–2016) Research Donation Generic
(2014–2018) Morris Animal Foundation
The role of gap junction channels, growth factors and cytokines in the diseased canine cornea
(2014–2018) Canine Research Foundation
The role of gap junction channels, growth factors, and cytokines in the diseased canine cornea
(2014–2018) Peter & Mary Ellen Stone Memorial Fund
(2014) UQ Major Equipment and Infrastructure
Canine induced pluripotent stem cells as a resource for treating canine osteoarthritis
(2012–2013) John & Mary Kibble Trust
Canine Induced Pluripotent Stem Cells as a Resource for Treating Canine Osteoarthritis
(2011–2012) John & Mary Kibble Trust
Canine Induced Pluripotent Stem Cells as a Resource for Treating Canine Osteoarthritis
(2011–2012) Australian Companion Animal Health Foundation
Canine induced pluripotent stem cells as a resource for treating canine osteoarthritis
(2010–2011) John & Mary Kibble Trust
A stem cell based approach to the treatment of devil facial disease in the Tasmanian Devil (Sarcophilus harrisli)
Doctor Philosophy — Principal Advisor
Other advisors:
A pre-clinical trial using in vitro-derived mesenchymal stem cells to effect cartilage repair in a canine model of osteoarthritis
Doctor Philosophy — Principal Advisor
Other advisors:
Improving efficiency of embryo technologies to expedite livestock genetic gain
Doctor Philosophy — Associate Advisor
Investigate gap junction (GJ) activity in canine ocular diseases
Doctor Philosophy — Associate Advisor
Other advisors:
The development of non-invasive techniques for quantifying steroid hormone levels in wild cetaceans
Doctor Philosophy — Associate Advisor
Other advisors:
(2016) Doctor Philosophy — Associate Advisor
Other advisors: