Dr Felicity Han

Postdoctoral Fellow

UQ Centre for Clinical Research
Faculty of Medicine
f.han@uq.edu.au
+61 7 334 69718

Overview

Research Interests

  • 1. Nanotechnology in pain management: Novel analgesic drug delivery strategies to alleviate intractable cancer-related pain.
  • 2. Probing molecular mechanisms of individual chronic pain conditions with particular focus on Cancer Chemotherapy Induce Neuropathic Pain (CIPN) for novel pain therapeutics discovery.

Research Impacts

The optimised rat model of cancer chemotherapy induced peripheral neuropathy (CIPN) that Dr. Han established and pharmacologically characterized as part of her PhD research addressed the limitations of all previously published models of this painful condition. This model is now being used routinely by the CIPDD/TetraQ research team to identify which novel molecules from drug discovery programs can alleviate this type of pain so that the best molecules so-identified can be progressed towards clinical trials in patients.

The management of moderate to severe persistent pain associated with advanced cancer is a great challenge to clinicians. There is a great need for sustained release formulation of strong analgesics (that Dr. Han has been working on). This means that for patients who do not respond well to painkillers given as tablets or conventional injections, one injection containing the sustained release microparticles into the fluid surrounding the spinal cord, will lead to well-controlled pain for several weeks. The novel sustained-release microparticles analgesic drug formulation has the potential to have a major impact by improving the quality of life of patients who would otherwise suffer from intractable cancer-related pain.

Qualifications

  • PhD, The University of Queensland

Publications

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Supervision

  • Doctor Philosophy

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Publications

Journal Article

Other Outputs

PhD and MPhil Supervision

Current Supervision