Dr Dhanisha Jhaveri

Senior Research Fellow

Mater Research Institute-UQ
Faculty of Medicine

Senior Research Fellow

Queensland Brain Institute
dhanisha@uq.edu.au
+61 7 344 37095
+61 7 334 66381

Overview

Dr Dhanisha Jhaveri has a joint appointment at Mater Research and the Queensland Brain Institute (QBI) and is a Mater Foundation Senior Research Fellow and a Group Leader. Dhanisha’s research group is investigating the fundamental mechanisms that drive the renewal of neurons in the adult brain, with the goal of harnessing this form of neural plasticity to relieve the emotional and cognitive burdens associated with chronic stress and depression.

Dhanisha received her PhD from the Tata Institute of Fundamental Research (TIFR), India, under the supervision of Professor Veronica Rodrigues, where she unravelled the molecular mechanisms that wire the olfactory axons in the fly (Drosophila) brain. In recognition of her doctoral work she was awarded the Indian National Science Academy medal for Young Scientist of the Year in 2003. Fascinated by the discovery that the production of new neurons continues in the adult brain, she then joined the laboratory of Professor Perry Bartlett at the Queensland Brain Institute as a Human Frontiers Science Program Postdoctoral Fellow. She has made major discoveries that have transformed our understanding of the regulation and roles of neural stem cells in the adult brain. Her work uncovered that a subclass clinical antidepressants directly activates neural stem cells in the hippocampus, a brain region implicated in regulating mood and cognitive functions. She also pioneered the development of a new cell sorting protocol to purify neural stem cells which revealed presence of distinct stem cell populations in this brain region.

Research Interests

  • Regenerating cells in the adult brain
    Investigating the fundamental mechanisms that drive the renewal of neurons in the adult brain, with the goal of harnessing this form of neural plasticity to relieve the emotional and cognitive burdens associated with chronic stress and depression.

Qualifications

  • Doctor of Philosophy, Tata Inst.
  • Master of Science, University of Pune
  • Bachelor of Science, University of Mumbai

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Master Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Jhaveri, Dhanisha J., Prosper, Boris W. and Bartlett, Perry F. (2013). Culturing and expansion of precursor cells from the adult hippocampus. In Brent A. Reynolds and Loic P. Deleyrolle (Ed.), Neural Progenitor Cells: Methods and Protocols (pp. 41-51) New York, NY, United States: Humana Press. doi:10.1007/978-1-62703-574-3_4

Journal Article

Conference Publication

  • Jhaveri, D., O'Keeffe, I., Robinson, G., Zhao, Q-Y., Zhang, Z. H., Nink, V., Osborne, G., Wray, N. and Bartlett, P. (2015). Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus. In: 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, (254-255). Aug 23-27, 2015.

  • Bartlett, P. F., Jhaveri, D. and Taylor, C. J. (2012). Activation of different neurogenic precursor populations in the hippocampus. In: Abstracts to the 19th Biennial Meeting of the International Society for Developmental Neuroscience. 19th Biennial Meeting of the International Society for Developmental Neuroscience (ISDN), Mumbai India, (625-625). 11-14 January 2012. doi:10.1016/j.ijdevneu.2012.03.330

  • Jhaveri, Dhanisha, Newcombe, Estella, Nink, Virginia, Osborne, Geoffrey, Vaidya, Vidita and Bartlett, Perry (2012). Norepinephrine stimulates a distinct precursor population in the adult hippocampus. In: 19th Biennial Meeting of the International-Society-for-Developmental-Neuroscience (ISDN), Mumbai, India, (669-669). 11-14 January 2012. doi:10.1016/j.ijdevneu.2012.03.332

  • Jhaveri, D. J., Nandam, L. S. and Bartlett, P. F. (2007). The slice-sphere assay: A combinatorial approach to evaluate neural precursor activity. In: 21st Biennial Meeting of the International-Society-for-Neurochemistry/38th Annual Meeting of the American-Society-for-Neurochemistry, Cancun Mexico, (185-185). Aug 19-24, 2007.

  • Bartlett, P. F., Young, K., Bull, N. and Jhaveri, D. (2006). Regulation of neural precursor survival, proliferation and differentiation by BDNF. In: International Journal of Developmental Neuroscience. 16th Biennial Meeting of the International-Society-for-Developmental-Neuroscience, Banff, Canada, (491-491). Aug 24-28, 2006. doi:10.1016/j.ijdevneu.2006.09.053

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

Completed Supervision