The University of Queensland

Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection

Alharbi, Nedaa, Shalash, Ahmed O., Koirala, Prashamsa, Boer, Jennifer C., Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2024). Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection. Journal of Colloid and Interface Science, 663, 43-52. doi: 10.1016/j.jcis.2024.02.134

Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation

Koirala, Prashamsa, Shalash, Ahmed O., Chen, Sung-Po R., Faruck, Mohammad O., Wang, Jingwen, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2024). Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation. Vaccines, 12 (2) 198, 1-14. doi: 10.3390/vaccines12020198

Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems

Jin, Shengbin, Zhang, Jiahui, Nahar, Ummey J., Huang, Wenbin, Alharbi, Nedaa A., Shalash, Ahmed O., Koirala, Prashamsa, Yang, Jieru, Kiong, Jolynn J. E., Khalil, Zeinab G., Capon, Robert J., Stephenson, Rachel J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2023). Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems. ACS Infectious Diseases, 9 (8), 1570-1581. doi: 10.1021/acsinfecdis.3c00159

Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape

Koirala, Prashamsa, Chen, Sung‐Po R., Boer, Jennifer C., Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Lu, Lantian, Faruck, Mohammad Omer, Shalash, Ahmed O., Bashiri, Sahra, Capon, Robert J., Hussein, Waleed M., Monteiro, Michael J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape. Advanced Functional Materials, 33 (12) 2209304, 2209304. doi: 10.1002/adfm.202209304

Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A Streptococcus

Kiong, Jolynn, Nahar, Ummey Jannatun, Jin, Shengbin, Shalash, Ahmed O., Zhang, Jiahui, Koirala, Prashamsa, Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2022). Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A Streptococcus. Pharmaceutics, 14 (10) 2151, 1-12. doi: 10.3390/pharmaceutics14102151

Perspectives in the vaccine development against Opisthorchis viverrini liver fluke

Shalash, Ahmed O., Skwarczynski, Mariusz and Toth, Istvan (2022). Perspectives in the vaccine development against Opisthorchis viverrini liver fluke. MedComm – Biomaterials and Applications, 1 (2) e21, 1-8. doi: 10.1002/mba2.21

Development of a peptide vaccine against hookworm infection: immunogenicity, efficacy, and immune correlates of protection

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Toth, Istvan and Skwarczynski, Mariusz (2022). Development of a peptide vaccine against hookworm infection: immunogenicity, efficacy, and immune correlates of protection. Journal of Allergy and Clinical Immunology, 150 (1), 157-169.e10. doi: 10.1016/j.jaci.2022.02.020

The potential of developing a protective peptide‐based vaccines against SARS‐CoV‐2

Shalash, Ahmed O., Toth, Istvan and Skwarczynski, Mariusz (2022). The potential of developing a protective peptide‐based vaccines against SARS‐CoV‐2. Drug Development Research, 83 (6), 1251-1256. doi: 10.1002/ddr.21969

Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Hussein, Waleed M., Chappell, Keith J., Watterson, Daniel, Young, Paul R., Skwarczynski, Mariusz and Toth, Istvan (2022). Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems. Pharmaceutics, 14 (4) 856, 856. doi: 10.3390/pharmaceutics14040856

Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens

Islam, Md. Tanjir, Ho, Mei-Fong, Nahar, Ummey J., Shalash, Ahmed O., Koirala, Prashamsa, Hussein, Waleed M., Stanisic, Danielle I., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2022). Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens. PLoS One, 17 (3) e0264961, e0264961. doi: 10.1371/journal.pone.0264961

Insights into the potential of rheological measurements in development of dry powder inhalation formulations

Almansour, Khaled, Alfagih, Iman M., Shalash, Ahmed O., Brockbank, Katrina, Ali, Raisuddin, Freeman, Tim and Elsayed, Mustafa M.A. (2022). Insights into the potential of rheological measurements in development of dry powder inhalation formulations. International Journal of Pharmaceutics, 614 121407, 121407. doi: 10.1016/j.ijpharm.2021.121407

Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay. Vaccines, 9 (12) 1493, 1-21. doi: 10.3390/vaccines9121493

Hookworm infection: Toward development of safe and effective peptide vaccines

Shalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Hookworm infection: Toward development of safe and effective peptide vaccines. Journal of Allergy and Clinical Immunology, 148 (6), 1394-1419.e6. doi: 10.1016/j.jaci.2021.10.013

Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold

Bojarska, Joanna, Mieczkowski, Adam, Ziora, Zyta, Skwarczynski, Mariusz, Toth, Istvan, Shalash, Ahmed O., Parang, Keykavous, El-Mowafi, Shaima A., Mohammed, Eman H. M., Elnagdy, Sherif, AlKhazindar, Maha and Wolf, Wojciech M. (2021). Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold. Biomolecules, 11 (10) 1515, 1515. doi: 10.3390/biom11101515

Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Skwarczynski, Mariusz and Toth, Istvan (2021). Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy. Vaccines, 9 (9) 1034, 1034. doi: 10.3390/vaccines9091034

Key considerations for the development of safe and effective SARS‐CoV‐2 subunit vaccine: a peptide‐based vaccine alternative

Shalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Key considerations for the development of safe and effective SARS‐CoV‐2 subunit vaccine: a peptide‐based vaccine alternative. Advanced Science, 8 (16) 2100985, 1-35. doi: 10.1002/advs.202100985

Chemical conjugation strategies for the development of protein-based subunit nanovaccines

Lu, Lantian, Duong, Viet Tram, Shalash, Ahmed O., Skwarczynski, Mariusz and Toth, Istvan (2021). Chemical conjugation strategies for the development of protein-based subunit nanovaccines. Vaccines, 9 (6) 563, 1-24. doi: 10.3390/vaccines9060563

Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery

Azuar, Armira, Li, Zhuoqing, Shibu, Mohini A., Zhao, Lili, Luo, Yacheng, Shalash, Ahmed O., Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery. Journal of Medicinal Chemistry, 64 (5) acs.jmedchem.0c01660, 2648-2658. doi: 10.1021/acs.jmedchem.0c01660

Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2

Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O., Joyce, Michael A., Saffran, Holly A., Day, Christopher J., Lepletier, Ailin, Spillings, Belinda L., Mills, Jamie-Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T., Stanisic, Danielle I., Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P., Toth, Istvan, Tyrrell, D. Lorne and Good, Michael F. (2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2. Clinical and Translational Immunology, 10 (3) e1260, e1260. doi: 10.1002/cti2.1260

The relationship between the permeability and the performance of carrier-based dry powder inhalation mixtures: new insights and practical guidance

Shalash, Ahmed O., Khalafallah, Nawal M., Molokhia, Abdulla M. and Elsayed, Mustafa M. A. (2018). The relationship between the permeability and the performance of carrier-based dry powder inhalation mixtures: new insights and practical guidance. AAPS PharmSciTech, 19 (2), 912-922. doi: 10.1208/s12249-017-0898-7

Modeling the performance of carrier-based dry powder inhalation formulations: Where are we, and how to get there?

Elsayed, Mustafa M. A. and Shalash, Ahmed O. (2018). Modeling the performance of carrier-based dry powder inhalation formulations: Where are we, and how to get there?. Journal of Controlled Release, 279, 251-261. doi: 10.1016/j.jconrel.2018.03.020

A New Role of Fine Excipient Materials in Carrier-Based Dry Powder Inhalation Mixtures: Effect on Deagglomeration of Drug Particles During Mixing Revealed

Shalash, Ahmed O. and Elsayed, Mustafa M. A. (2017). A New Role of Fine Excipient Materials in Carrier-Based Dry Powder Inhalation Mixtures: Effect on Deagglomeration of Drug Particles During Mixing Revealed. AAPS PharmSciTech, 18 (8), 2862-2870. doi: 10.1208/s12249-017-0767-4

Insights into the roles of carrier microstructure in adhesive/carrier-based dry powder inhalation mixtures: carrier porosity and fine particle content

Shalash, Ahmed O., Molokhia, Abdulla M. and Elsayed, Mustafa M. A. (2015). Insights into the roles of carrier microstructure in adhesive/carrier-based dry powder inhalation mixtures: carrier porosity and fine particle content. European Journal of Pharmaceutics and Biopharmaceutics, 96, 291-303. doi: 10.1016/j.ejpb.2015.08.006

Carrier microstructure and performance of dry powder inhalation mixtures: a step towards universal performance prediction model

Shalash, Ahmed O., Khalafallah, Nawal M., Molokhia, Abdulla M. and Elsayed, Mustafa M. A. (2017). Carrier microstructure and performance of dry powder inhalation mixtures: a step towards universal performance prediction model. The Drug Delivery to the Lungs 27th Conference, Edinburgh, Scotland, United Kingdom, 7-9 December 2016. New Rochelle, NY USA: Mary Ann Liebert Publishers.

Development of peptide-based vaccines against infectious diseases: hookworm, liver fluke, and SARS-CoV-2 virus

Shalash, Ahmed (2023). Development of peptide-based vaccines against infectious diseases: hookworm, liver fluke, and SARS-CoV-2 virus. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/ba5f3b6