Dr Bryan Fry

Associate Professor

School of Biological Sciences
Faculty of Science

Affiliate Associate Professor

Institute for Molecular Bioscience
bgfry@uq.edu.au
+61 7 336 58515
0400 193 182

Overview

Venoms play a range of adaptive roles in the animal kingdom from predation to defense to competitor deterrence. Remarkably, despite their biological importance and uniqueness, the evolution of venom systems is poorly understood. New insights into the evolution of venom systems and the importance of the associated toxins cannot be advanced without recognition of the true biochemical, ecological, morphological and pharmacological diversity of venoms and associated venom systems. A major limitation has been the very narrow taxonomical range studied. Entire groups of venomous animals remain virtually unstudied. My research is inherently interdisciplinary, integrating ecological, evolutionary, and functional genomics approaches in order to understand the evolution of venom systems. Studies range from discovering the shock-inducing hypotensive and anticoagulant venom of the iconic Komodo Dragon through to exploring the unique temperature specific adaptations of Antarctic octopus venoms.

Qualifications

  • Doctor of Philosophy, The University of Queensland

Publications

  • Debono, Jordan, Cochran, Chip, Kuruppu, Sanjaya, Nouwens, Amanda, Rajapakse, Niwanthi W., Kawasaki, Minami, Wood, Kelly, Dobson, James, Baumann, Kate, Jouiaei, Mahdokht, Jackson, Timothy N. W., Koludarov, Ivan, Low, Dolyce, Ali, Syed A., Smith, A. Ian, Barnes, Andrew and Fry, Bryan G. (2016) Canopy venom: proteomic comparison among new world arboreal pit-viper venoms. Toxins, 8 7: 210.1-210.19. doi:10.3390/toxins8070210

  • Walker, Andrew A., Weirauch, Christiane, Fry, Bryan G. and King, Glenn F. (2016) Venoms of heteropteran insects: a treasure trove of diverse pharmacological toolkits. Toxins, 8 2: . doi:10.3390/toxins8020043

  • Ali, Syed Abid, Alam, Mehtab, Abbasi, Atiya, Undheim, Eivind A. B., Fry, Bryan Grieg, Kalbacher, Hubert and Voelter, Wolfgang (2016) Structure-activity relationship of chlorotoxin-like peptides. Toxins, 8 2: . doi:10.3390/toxins8020036

View all Publications

Supervision

View all Supervision

Publications

Book Chapter

  • Fry, Bryan G., Richards, Renee S., Earl, Stephen, Cousin, Xavier, Jackson, Timothy N. W., Weise, Christoph and Sunagar, Kartik (2015). Lesser-known or putative reptile toxins. In B. G. Fry (Ed.), Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery (pp. 364-407) New York, NY, United States: Oxford University Press.

  • Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D., Reeks, T. and Sunagar, K. (2015). Research methods. In Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery (pp. 153-214) New York, NY, United States: Oxford University Press.

  • Fry, Bryan G., Koludarov, Ivan, Jackson, Timothy N. W., Holford, Mandë, Terrat, Yves, Casewell, Nicholas R., Undheim, Eivind A. B., Vetter, Irina, Ali, Syed A., Low, Dolyce H. W. and Sunagar, Kartik (2015). Seeing the woods for the trees: understanding venom evolution as a guide for biodiscovery. In Glenn F. King (Ed.), Venoms to drugs: venom as a source for the development of human therapeutics (pp. 1-36) Cambridge, United Kingdom: Royal Society of Chemistry. doi:10.1039/9781849737876-00001

  • Dutertre, Sebastien, Undheim, Eivind, Pineda, Sandy S., Jin, Ai-Hua (Jean), Lavergne, Vincent, Fry, Bryan G., Lewis, Richard J., Alewood, Paul F. and King, Glenn F. (2015). Venoms-Based Drug Discovery: Proteomic and Transcriptomic Approaches. In King, Glenn F (Ed.), Venoms to Drugs (pp. 80-96) London, United Kingdom: Royal Society of Chemistry. doi:10.1039/9781849737876-00080

Journal Article

Conference Publication

  • Undheim, Eivind A. B., Jones, Alun, Holland, John W., Morales, Rodrigo A. V., Winnen, Brit, Fry, Bryan G. and King, Glenn F. (2012). Centipede venoms: Old and unusual. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (126-126). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.065

  • Morgenstern, David, de la Vega, Ricardo C. Rodriguez, Ott, Michael, King, Glenn F. and Fry, Bryan G. (2012). Functional redundancy in venoms is an evolutionary by-product. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (123-124). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.059

  • Goldstein, Ellie J.C., Tyrrell, Kerrin L., Citron, Diane M., Cox, Cathleen R., Recchio, Ian M., Okimoto, Ben, Bryja, Judith and Fry, Bryan G. (2012). How do Komodo Dragons kill their prey?: Lack of role for oral flora in predation. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (245-245). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.293

  • Fry, Bryan G., Ruder, Tim, Georgieva, Dessi N., Morgenstern, David, King, Glenn and Undheim, Eivind A. B. (2012). Tentacles of venom: Molecular evolution of coleoid venoms. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (125-125). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.063

  • Pineda, Sandy S., Wong, Emily S., Fry, Bryan G., Binford, Greta J. and King, Glenn F. (2012). Understanding the chemical diversity and evolution of spider venoms using comparative transcriptomics. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (234-234). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.270

  • Jin, Aihua, Tsampazi, Maria, Hodgson, Wayne, Wickramaratana, Janith, Lemme, Scott, Beuve, Anne, Garbers, David, Fry, Bryan, Torres, Allan M. and Alewood, Paul (2005). The SAR of novel TNP snake toxins. In: Peptides 2004, Proceedings. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, (431-432). Sep 05-10, 2004.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

Completed Supervision