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extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer… Hypoxia increases the exosome release from ovarian cancer cells and promotes the epithelial-mesenchymal transition of target cells… Extracellular vesicles and ovarian cancer… UniQuest-INOVIQ Umbrella Research and Option Agreement: Exosome based ovarian cancer screening… realistic that a clinically useful antenatal screening test can be developed. Unlike diseases such as cancer… Assays for clinically relevant complications (including ovarian cancers, and obstetrical syndromes… Pancreatic cancer is the fourth most common cause of death due to cancer in the world. It is known…
I am Professor, NHMRC Investigator Fellow (EL2) and group leader (Exosome Biology Laboratory) at UQ Centre for Clinical Research. I am nationally and internationally (>20 invitations to international meetings in the last 5 years) acknowledged key opinion leader on Extracellular Vesicle (rated 3th w …
My research program focused on obstetrics and gynaecology, and it has investigated the release of extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer progression, and their utility as a biomarker for a wide range of pregnancy complications, and ovarian cancer. …
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Cell biology: Ran, mitosis and the cancer Lconnection… Cancer chemotherapy… studying cancer, autoimmune diseases, infection and immunity, and the genetic basis of disease… -9 phosphorylation in the regulation of apoptosis during development and in pathological states, including cancer.…
Paul Clarke is Director of the Frazer Institute, a leading translational medical research centre studying cancer, autoimmune diseases, infection and immunity, and the genetic basis of disease. Professor Clarke became Director in 2017 and was previously Associate Dean (Research) in Medicine at the Un …
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selection in vaccine response; 3. Unraveling novel pathways sustaining T cell immunity in cancers… cancers by preventing a loss-of-function program termed 'exhaustion'. This research program has…
I am a Senior Research Fellow, NHMRC Emerging Leader Fellow, and Group Leader at UQ Frazer Institute. I was awarded my PhD in late 2017 by Biomedicine Discovery Institute, Monash University. Under the UQ Health Research Accelerator (HERA) program, I lead a team to investigate T and B cell responses …
Overall, I published 13x journal articles (6x 1st author or joint 1st author, 1x corresponding author) and 1x book chapter (1st author). The quality of my research in the field of T cell immunology was highlighted by three cutting-edge works published in Nature Immunology ( joint 1st author, 2021, s …
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immunological defenses and cancer immunosurveillance. Current research: My current research focuses… The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy… Reversing tumour necrosis factor-mediated immunosuppression to boost immunity against experimental CD19+ blood cancers… Background: Despite advances in treatment and earlier detection, cancer is… NK cells are highly efficient at preventing cancer metastasis but are infrequently found in the…
In 2012, I achieved a significant milestone by becoming the first student to complete a doctoral degree from the prestigious International PhD Program at Institute Pasteur, Paris/France. This accomplishment not only set the trajectory of my academic pursuits but also underscored my dedication and pa …
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SCG10-like protein (SCLIP) is a STAT3-interacting protein involved in maintaining epithelial morphology in MCF-7 breast cancer cells… movement of cancer cells from one site to another, involves remodeling of the cytoskeleton including…
Dr Dominic Ng graduated with a BSc (Hons) and gained his PhD from the University of Western Australia. His doctoral studies, conducted in the laboratory of Assoc. Prof. Marie Bogoyevitch, were focused on cardiomyocyte signalling mechanisms regulating pathological tissue growth (ie cardiac hypertroph …
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Cancer treatment can be severely toxic to women's eggs. Increasing numbers of women who survive… SAC signal. The aneuploidy and cancer predispositions of individuals who harbour genetic mutations in…
I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditatio …
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Local doxorubicin delivery via 3Dāprinted porous scaffolds reduces systemic cytotoxicity and breast cancer recurrence in mice… projects on cancer and bone tissue engineering. Dr Shafiee has developed innovative tissue engineered… The concept of using macroscale porous scaffolds as local drug reservoirs to prevent cancer…
Dr Abbas Shafiee is a tissue engineering & regenerative medicine scientist interested in translational cell-based and tissue engineering strategies to treat human diseases.
Dr Shafiee completed his PhD in Professor Kiarash Khosrotehrani’s laboratory on stem cell biology. His research career durin …
My research program has been devoted to understanding human tissue development to develop advanced technologies for tissue regeneration.
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