You searched for: cancer
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Primarily endometrial cancer… Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer… Identifying the regulatory targets of common endometrial cancer risk variants… We and our international Endometrial Cancer Association Consortium collaborators have identified… Gynaecological cancer genetics… -enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research… Excessive exposure to estrogen is a well-established risk factor for endometrial cancer (EC…
After completing his BSc and MSc (Hons) at the University of Canterbury (NZ), Dylan worked for five years as a Research Scientist at Antisoma Research Limited (London, UK), developing antibody-enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research into an …
Large numbers of germline genetic variants have been found to associate with disease. A major roadblock in our understanding of how genetics contribute to disease has been a lack of knowledge of the molecular effects of variants. Thus, the aim of my research program is to use genetic analyses to ass …
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Therapeutic Opportunity in Cancers with Poor Survival… Complex neoantigen prediction in cancers… genome sequencing technologies in biomedical research. In particular large cancer research…
Research officer, Medical Genomics
QIMR Berghofer Medical Research Institute
My research addressed the challenges related to key genomic components in tumour-immune editing variation in cancers with poor survival and predicting the responses to cancer immunotherapies. Characterizing genomic determinants in underlying response and resistance to cancer immunotherapy. Through w …
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Using published datasets, and tissue donated by Brisbane breast cancer patients, we're trying to… Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R… Development of new theranostic agents for metastatic breast cancer surveillance and treatment… Molecular validation of autofluorescence and narrow band imaging of oral cancer resection margins… Most of the time, treatments for early breast cancer successfully prevent metastatic spread, but… Biomarkers of triple-negative breast cancer progression and response to therapy… cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research… BRCA1 is a breast cancer susceptibility gene that is down-regulated in the majority of cases of…
Dr Jodi Saunus is a senior fellow who specialises in translational research on metastatic breast cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research in 2022 to help facilitate patient-focused research at the interface of biomedical R&D and clinical pra …
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Melanoma is the fourth most common cancer with >11,000 Australians diagnosed each year resulting… transcriptome, methylation) as well as Spatial Profiling to greater understand the early hallmarks of pre-skin cancer development.… Single nucleotide polymorphisms in obesity-related genes and the risk of esophageal cancers… Laser capture microdissection to empower cancer discoveries, improve diagnosis, treatment and outcomes in amyloidosis patients… development a Genomics Atlas of pre-skin cancer lesions. If you are interested to hear… Genomics Atlas of pre-skin cancer lesions… biomarkers for melanoma progression and the development a Genomics Atlas of pre-skin cancer… Epigenetic gene inactivation of tumour suppressor genes underlies several human cancers. The…
Dr Mitchell Stark is a molecular biologist and Group Leader/Senior Research Fellow from the Dermatology Research Centre (DRC) based at the Frazer Institute. His group has extensive experience in microRNA biology and biomarker discovery, next-generation sequencing, bioinformatics, and functional anal …
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modalities of neoadjuvant therapy – results from the AGITG DOCTOR trial and the cancer evolution biobank… Cancer genetics… Barbour. Dr Brosda was awarded a PhD in bioinformatics and cancer genetics from the… set of 89 esophageal cancer samples. The most hypermethylated tumors showed worse patient survival.…
Dr Sandra Brosda is a Research Fellow within the Surgical Oncology group led by Professor Andrew Barbour.
Dr Brosda was awarded a PhD in bioinformatics and cancer genetics from the University of Queensland in November 2020. Her research focused on biomarker discovery and intra-tumour heterogeneity …
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Development of novel therapeutics for melanoma and non-melanoma cancer… Hypoxia-induced stress responses in cancer and cancer stem cells… Skin Cancer… ) promotes stress and death of the organism. However, cancer cells have evolved adaptive mechanisms to…
Researcher Biography
Dr Snehlata Kumari is the head of skin inflammation and immunity laboratory at the Frazer Institute, the University of Queensland in Brisbane, Australia. She is a board member of the Australasian Society for Dermatology Research (ASDR).
After PhD and post-doctoral training in …
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Cancers induce immunosuppressive mechanisms, and immunotherapy can either alleviate… early cancer detection and disease monitoring. These specific adaptive immune receptors are essential… Immunotherapy for persisting viral infection and associated cancer… Approaching antigen-presenting cell immunotherapy for cervical cancers using single-cell transcriptomics… health and in cancer. Dr. Tuong was born and raised in Singapore and moved to Brisbane… precancerous neoplasia that can eventuate in cervical cancer. Dendritic cells (DCs) are efficient in priming…
Dr. Kelvin Tuong is a Senior Research Fellow/Group Leader at the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR), Child Health Research Centre. He is interested in single-cell analysis of immune cells and harnessing adaptive immune receptors for understanding immune cell development …
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Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles… . The procedure was done to treat ulcerative pancolitis complicated by colon cancer. She had a well…
Associate Professor Jakob Begun is the IBD Group leader in the Immunity, Infection, and Inflammation Program at Mater Research University of Queensalnd, and has a basic and translational laboratory at the Translational Research Institute in Brisbane. He is an Associate Professor in the University of …
Inflammatory bowel disease(IBD) is a complex disease with genetic and environmental triggers. The microbiota is one of the biggest environmental contributors and interest in its impact on human health and disease is a growing. Studies in IBD have led the way in identifying disease associated microbi …
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Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts… vulnerability to cancer. Despite this increased cancer risk, there are no widely accepted guidelines for…
David is a Consultant Paediatrician, Metabolic Physician, Clinical Geneticist and clinician researcher. His area of expertise is the diagnosis and management of children with rare diseases. David is involved in multiple ongoing research projects aimed at novel disease discovery, improved diagnostic …
David has close relationships with research colleagues both in Australia and internationally. He has multiple ongoing research projects investigating novel disease identification, the genetics of paediatric speech disorders and the development of new therapeutic possibilities for children and adults …
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Cancer treatment can be severely toxic to women's eggs. Increasing numbers of women who survive… SAC signal. The aneuploidy and cancer predispositions of individuals who harbour genetic mutations in…
I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditatio …
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