You searched for: evolutionary genetics
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evolutionary position of sponges, outcomes of this project expect to reveal the cardinal rules… Evolutionary distinctiveness and status of the endangered Lake Eacham rainbowfish (Melanotaenia eachamensis)… for evolutionary, ecological and mechanistic aspects of animal-bacterial symbiosis… Evolutionary and ecological genomics of marine invertebrate animals. Animals evolve… evolutionarily-conserved molluscan insulin-like peptide (Has-MIP), (2) a gastropod-specific…
Evolutionary and ecological genomics of marine invertebrate animals.
Animals evolve because their genomes need to respond to the constantly changing environment presented by both their external habitat and their internal microbial symbionts. Over evolutionary time, these different factors interact …
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Highly scalable phylogenomic approaches are needed to make evolutionary sense of the ongoing deluge… Analysis of Alexandrium tamarense (Dinophyceae) genes reveals the complex evolutionary history of a microbial eukaryote… Symbiodinium: the evolutionary transition to coral reef symbiont… transporters or their evolutionary histories in the red algae. Here we examined 482 expressed sequence tag…
Dr Chan has a PhD in Genomics and Computational Biology from UQ. He underwent postdoctoral training at Rutgers University (USA) in algal genomics and evolution. He returmed to UQ in late 2011 as one of the inaugural Great Barrier Reef Foundation Bioinformatics Fellows.
Dr Chan joined the School of …
Chan has published 100 scholarly publications in the areas of microbial genomics, evolutionary biology, and bioinformatics. His research work continuously challenges the working hypotheses in evolutionary biology. This body of work demonstrates a single origin of Archaeplastida (Plantae), the founda …
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The X factor: X chromosome dosage compensation in the evolutionarily divergent monotremes and marsupials… Marsupials and monotremes represent evolutionarily divergent lineages from the majority of extant…
I completed a BSc (Hons) and a PhD at the University of Melbourne before undertaking post-doctoral research at the University of California, Berkeley, and the University of Texas MD Anderson Cancer Center, Houston. My research focused on marsupial and eutherian developmental biology, going off piste …
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the evolutionary success of a protein, and to re-run evolution to generate proteins that perform in… Plants and the animals that consume them are locked in an evolutionary battle involving chemical… Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust… reconstructing ancestral precursors and evolutionary pathways, to answer such questions as how did the… useful recombination sites in amino acid sequences with unknown structure and unknown evolutionary origin…
The molecular evolution of cytochrome P450 Enzymes: biological catalysts of unprecedented versatility.
Cytochrome P450 enzymes (CYPs, P450s) especially those responsible for drug metabolism in humans, are the unifying theme of the research in our lab. These fascinating enzymes are catalysts of exce …
Our research is leading to the development of more sustainable, environmentally friendly, chemical processes to accelerate drug development and improve the safety of medicines. Our studies into the evolution of catalytic promiscuity in P450s reveal how organisms have evolved to deal with chemicals i …
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