Journal Article: Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011
Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 487. doi: 10.3390/md21090487
Journal Article: Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 ARTN e90408. doi: 10.7554/elife.90408
Journal Article: Case Studies in Molecular Network-Guided Marine Biodiscovery
Khushi, Shamsunnahar, Salim, Angela A. and Capon, Robert J. (2023). Case Studies in Molecular Network-Guided Marine Biodiscovery. Marine Drugs, 21 (7) 413, 413. doi: 10.3390/md21070413
Australian marine microbes as a source of next generation antiparasitics
(2022–2025) Marine Bioproducts Cooperative Research Centre
NOMETA MICROBIAL BIODISCOVERY: ACCESSING NEW CHEMICAL SPACE TO DISCOVER NEW ANTIBIOTIC CLASSES
Doctor Philosophy
Medicinal chemistry of new Nature-inspired treatments for Inflammatory Bowel Disease (IBD)
Doctor Philosophy
The discovery of new antibiotics to combat drug resistance
Doctor Philosophy
Khalil, Zeinab G., Salim, Angela A. and Capon, Robert J. (2020). Microbioreactor techniques for the production and spectroscopic characterization of microbial peptides. Peptide synthesis: methods and protocols. (pp. 303-322) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_21
Nuclear magnetic resonance case studies in marine natural products
Salim, Angela A., Piggott, Andrew M. and Capon, Robert J. (2017). Nuclear magnetic resonance case studies in marine natural products. Modern NMR Approaches to the Structure Elucidation of Natural Products: Volume 2: Data Acquisition and Applications to Compound Classes. (pp. 403-439) edited by Antony J. Williams, Gary E. Martin and David Rovnyak. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849734684-00403
Nuclear magnetic resonance case studies in microbial natural products
Piggott, Andrew M., Salim, Angela A. and Capon, Robert J. (2017). Nuclear magnetic resonance case studies in microbial natural products. Modern NMR Approaches to the Structure Elucidation of Natural Products: Volume 2: Data Acquisition and Applications to Compound Classes. (pp. 440-485) edited by Antony J. Williams, Gary E. Martin and David Rovnyak. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849734684-00440
Salim, Angela A., Chin, Young-Won and Kinghorn, A. Douglas (2008). Drug discovery from plants. Bioactive molecules and medicinal plants. (pp. 1-24) edited by K. G. Ramawat and J. M. Merillon. Berlin, Heidelberg, Germany: Springer Berlin Heidelberg. doi: 10.1007/978-3-540-74603-4_1
Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 487. doi: 10.3390/md21090487
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 ARTN e90408. doi: 10.7554/elife.90408
Case Studies in Molecular Network-Guided Marine Biodiscovery
Khushi, Shamsunnahar, Salim, Angela A. and Capon, Robert J. (2023). Case Studies in Molecular Network-Guided Marine Biodiscovery. Marine Drugs, 21 (7) 413, 413. doi: 10.3390/md21070413
Samarasekera, Kaumadi, Hussein, Waleed M., Wu, Taizong, Salim, Angela A. and Capon, Robert J. (2023). Glyclauxins A–E: dimeric oxaphenalenone aminoglycosides from an Australian wasp nest-derived fungus Talaromyces sp. CMB-MW102. Journal of Natural Products, 86 (3), 517-525. doi: 10.1021/acs.jnatprod.2c01069
Natural products as anthelmintics: safeguarding animal health
Salim, Angela A., Butler, Mark S., Blaskovich, Mark A. T., Henderson, Ian R. and Capon, Robert J. (2023). Natural products as anthelmintics: safeguarding animal health. Natural Product Reports, 40 (11), 1754-1808. doi: 10.1039/d3np00019b
Wu, Taizong, Salim, Angela A., Bernhardt, Paul V. and Capon, Robert J. (2022). Molecular networking and cultivation profiling reveals diverse natural product classes from an Australian soil-derived fungus Aspergillus sp. CMB-MRF324. Molecules, 27 (24) 9066, 1-17. doi: 10.3390/molecules27249066
Salim, Angela A., Samarasekera, Kaumadi, Wu, Taizong and Capon, Robert J. (2022). Phoslactomycins revisited: polyketide tetrahydrofurans and lactones from an Australian wasp nest-derived Streptomyces sp. CMB-MW079. Organic Letters, 24 (40), 7328-7333. doi: 10.1021/acs.orglett.2c02791
Wu, Taizong, Salim, Angela A., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2022). Glenthmycins A–M: macrocyclic spirotetronate polyketide antibacterials from the Australian pasture plant-derived Streptomyces sp. CMB-PB041. Journal of Natural Products, 85 (6), 1641-1657. doi: 10.1021/acs.jnatprod.2c00444
Secreted NF-κB suppressive microbial metabolites modulate gut inflammation
Giri, Rabina, Hoedt, Emily C., Khushi, Shamsunnahar, Salim, Angela A., Bergot, Anne-Sophie, Schreiber, Veronika, Thomas, Ranjeny, McGuckin, Michael A., Florin, Timothy H., Morrison, Mark, Capon, Robert J., Ó Cuív, Páraic and Begun, Jakob (2022). Secreted NF-κB suppressive microbial metabolites modulate gut inflammation. Cell Reports, 39 (2) 110646, 110646. doi: 10.1016/j.celrep.2022.110646
Wu, Taizong, Salim, Angela A., Cui, Hui, Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2022). Glenthenamines A–F: enamine pyranonaphthoquinones from the Australian pasture plant derived Streptomyces sp. CMB-PB042. Journal of Natural Products, 85 (2) acs.jnatprod.1c00821, 337-344. doi: 10.1021/acs.jnatprod.1c00821
Song, Fuhang, Yang, Na, Khalil, Zeinab G., Salim, Angela A., Han, Jiahui, Bernhardt, Paul V., Lin, Rui, Xu, Xiuli and Capon, Robert J. (2021). Bhimamycin J, a rare benzo[f]isoindole-dione alkaloid from the marine-derived actinomycete Streptomyces sp. MS180069. Chemistry and Biodiversity, 18 (11) e2100674, e2100674. doi: 10.1002/cbdv.202100674
Wu, Taizong, Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2021). Polycyclic C-deoxyaminoglycoside-polyketides from an Australian Pasture Plant Derived Streptomyces sp.. Organic Letters, 23 (21) acs.orglett.1c02954, 8224-8228. doi: 10.1021/acs.orglett.1c02954
Wu, Taizong, Salim, Angela A. and Capon, Robert J. (2021). Millmerranones A–F: a meroterpene cyclic carbonate and related metabolites from the Australian fungus Aspergillus sp. CMB-MRF324. Organic Letters, 23 (21) acs.orglett.1c03150, 8424-8428. doi: 10.1021/acs.orglett.1c03150
Methods in microbial biodiscovery
Salim, Angela A., Khalil, Zeinab G., Elbanna, Ahmed H., Wu, Taizong and Capon, Robert J. (2021). Methods in microbial biodiscovery. Marine Drugs, 19 (9) 503. doi: 10.3390/md19090503
Chemical cues that attract cannibalistic cane toad (Rhinella marina) larvae to vulnerable embryos
Crossland, Michael R., Salim, Angela A., Capon, Robert J. and Shine, Richard (2021). Chemical cues that attract cannibalistic cane toad (Rhinella marina) larvae to vulnerable embryos. Scientific Reports, 11 (1) 12527, 12527. doi: 10.1038/s41598-021-90233-3
Khushi, Shamsunnahar, Salim, Angela A., Elbanna, Ahmed H., Nahar, Laizuman and Capon, Robert J. (2021). New from old: Thorectandrin alkaloids in a Southern Australian marine sponge, Thorectandra choanoides (CMB-01889). Marine Drugs, 19 (2) 97, 1-10. doi: 10.3390/md19020097
Amaurones A–K: polyketides from the fish gut-derived Fungus Amauroascus sp. CMB-F713
Wu, Taizong, Salim, Angela A., Bernhardt, Paul V. and Capon, Robert J. (2021). Amaurones A–K: polyketides from the fish gut-derived Fungus Amauroascus sp. CMB-F713. Journal of Natural Products, 84 (2) acs.jnatprod.0c01343, 474-482. doi: 10.1021/acs.jnatprod.0c01343
Lincolnenins A–D: isomeric bactericidal bianthracenes from Streptomyces lincolnensis
Mohamed, Osama G., Khalil, Zeinab G., Salim, Angela A., Cui, Hui, Blumenthal, Antje and Capon, Robert J. (2020). Lincolnenins A–D: isomeric bactericidal bianthracenes from Streptomyces lincolnensis. The Journal of Organic Chemistry, 86 (16) acs.joc.0c02492, 11011-11018. doi: 10.1021/acs.joc.0c02492
Exploring natural product artifacts: the polyketide enterocin warms to a ballet of isomers
Salim, Angela A., Samarasekera, Kaumadi, Khalil, Zeinab G. and Capon, Robert J. (2020). Exploring natural product artifacts: the polyketide enterocin warms to a ballet of isomers. Organic Letters, 22 (12) acs.orglett.0c01629, 4828-4832. doi: 10.1021/acs.orglett.0c01629
Khushi, Shamsunnahar, Salim, Angela A., Elbanna, Ahmed H., Nahar, Laizuman, Bernhardt, Paul V. and Capon, Robert J. (2020). Dysidealactams and dysidealactones: sesquiterpene glycinyl-lactams, imides, and lactones from a Dysidea sp. marine sponge collected in Southern Australia. Journal of Natural Products, 83 (5) acs.jnatprod.0c00041, 1577-1584. doi: 10.1021/acs.jnatprod.0c00041
Mohamed, Osama G., Salim, Angela A., Khalil, Zeinab G., Elbanna, Ahmed H., Bernhardt, Paul V. and Capon, Robert J. (2020). Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294. Journal of Natural Products, 83 (2) acs.jnatprod.9b01181, 497-504. doi: 10.1021/acs.jnatprod.9b01181
Khushi, Shamsunnahar, Nahar, Laizuman, Salim, Angela A. and Capon, Robert J. (2020). Trachycladindoles H–M: molecular networking guided exploration of a library of southern Australian marine sponges. Australian Journal of Chemistry, 73 (4), 338-343. doi: 10.1071/ch19567
Neupane, Pratik, Salim, Angela A. and Capon, Robert J. (2020). Structure revision of the rare sponge metabolite echinosulfone A, and biosynthetically related echinosulfonic acids A–D. Tetrahedron Letters, 61 (12) 151651, 1-3. doi: 10.1016/j.tetlet.2020.151651
Jiao, Wei-Hua, Salim, Angela A., Khalil, Zeinab G., Dewapriya, Pradeep, Lin, Hou-Wen, Butler, Mark S. and Capon, Robert J. (2019). Trivirensols: selectively bacteriostatic sesquiterpene trimers from the Australian termite nest-derived fungus Trichoderma virens CMB-TN16. Journal of Natural Products, 82 (11), 3165-3175. doi: 10.1021/acs.jnatprod.9b00760
The effects of conspecific alarm cues on larval cane toads (Rhinella marina)
Crossland, Michael R., Salim, Angela A., Capon, Robert J. and Shine, Richard (2019). The effects of conspecific alarm cues on larval cane toads (Rhinella marina). Journal of Chemical Ecology, 45 (10), 838-848. doi: 10.1007/s10886-019-01111-2
Kalansuriya, Pabasara, Khalil, Zeinab G., Salim, Angela A. and Capon, Robert J. (2019). Talarophenol sulfate and talarophilones from the Australian mud dauber wasp-associated fungus, Talaromyces sp. CMB-W045. Tetrahedron Letters, 60 (43) 151157, 151157. doi: 10.1016/j.tetlet.2019.151157
Prasad, Pritesh, Salim, Angela A., Khushi, Shamsunnahar, Khalil, Zeinab G., Quezada, Michelle and Capon, Robert J. (2019). Solvolysis artifacts: leucettazoles as cryptic macrocyclic alkaloid dimers from a Southern Australian marine sponge, Leucetta sp.. Marine Drugs, 17 (2) md17020106, 106. doi: 10.3390/md17020106
Bromocatechol conjugates from a Chinese marine red alga, Symphyocladia latiuscula
Xu, Xiuli, Yang, Haijin, Khalil, Zeinab G., Yin, Liyuan, Xiao, Xue, Salim, Angela A., Song, Fuhang and Capon, Robert J. (2019). Bromocatechol conjugates from a Chinese marine red alga, Symphyocladia latiuscula. Phytochemistry, 158, 20-25. doi: 10.1016/j.phytochem.2018.10.026
Atif, Mohammed, Smith, Jennifer J., Estrada-Mondragon, Argel, Xiao, Xue, Salim, Angela A., Capon, Robert J., Lynch, Joseph W. and Keramidas, Angelo (2019). GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance. PLOS Pathogens, 15 (1) e1007570, e1007570. doi: 10.1371/journal.ppat.1007570
Jiao, Wei-Hua, Dewapriya, Pradeep, Mohamed, Osama, Khalil, Zeinab G., Salim, Angela A., Lin, Hou-Wen and Capon, Robert J. (2018). Divirensols: Sesquiterpene Dimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16. Journal of Natural Products, 82 (1) acs.jnatprod.8b00746, 87-95. doi: 10.1021/acs.jnatprod.8b00746
Cacolides: sesterterpene butenolides from a Southern Australian marine sponge, Cacospongia sp.
Khushi, Shamsunnahar, Nahar, Laizuman, Salim, Angela and Capon, Robert (2018). Cacolides: sesterterpene butenolides from a Southern Australian marine sponge, Cacospongia sp.. Marine Drugs, 16 (11) 456, 456. doi: 10.3390/md16110456
Dewapriya, Pradeep, Khalil, Zeinab G., Prasad, Pritesh, Salim, Angela A., Cruz-Morales, Pablo, Marcellin, Esteban and Capon, Robert J. (2018). Talaropeptides A-D: Structure and Biosynthesis of Extensively N-methylated Linear Peptides From an Australian Marine Tunicate-Derived Talaromyces sp. Frontiers in Chemistry, 6 394, 394. doi: 10.3389/fchem.2018.00394
Pursuing sesterterpene lactams in Australian Irciniidae sponges
Prasad, Pritesh, Zhang, Ailian, Salim, Angela A and Capon, Robert J (2018). Pursuing sesterterpene lactams in Australian Irciniidae sponges. Fitoterapia, 126, 83-89. doi: 10.1016/j.fitote.2017.09.003
Jiao, Wei-Hua, Khalil, Zeinab, Dewapriya, Pradeep, Salim, Angela A, Lin, Hou-Wen and Capon, Robert J (2018). Trichodermides A-E: New peptaibols isolated from the Australian termite nest-derived fungus trichoderma virens CMB-TN16. Journal of Natural Products, 81 (4), 976-984. doi: 10.1021/acs.jnatprod.7b01072
Chemical Diversity from a Chinese Marine Red Alga, Symphyocladia latiuscula
Xu, Xiuli, Yang, Haijin, Khalil, Zeinab G, Yin, Liyuan, Xiao, Xue, Neupane, Pratik, Bernhardt, Paul V, Salim, Angela A, Song, Fuhang and Capon, Robert J (2017). Chemical Diversity from a Chinese Marine Red Alga, Symphyocladia latiuscula. Marine drugs, 15 (12) 374, 1-10. doi: 10.3390/md15120374
Quezada, Michelle, Licona-Cassani, Cuauhtemoc, Cruz-Morales, Pablo, Salim, Angela A., Marcellin, Esteban, Capon, Robert J. and Barona-Gomez, Francisco (2017). Diverse cone-snail species harbor closely related streptomyces species with conserved chemical and genetic profiles, including polycyclic tetramic acid macrolactams. Frontiers in Microbiology, 8 (NOV) 2305, 2305. doi: 10.3389/fmicb.2017.02305
Khalil, Zeinab G., Salim, Angela A., Vuong, Daniel, Crombie, Andrew, Lacey, Ernest, Blumenthal, Antje and Capon, Robert J. (2017). Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494. The Journal of Antibiotics, 70 (12), 1097-1103. doi: 10.1038/ja.2017.119
Shang, Zhuo, Raju, Ritesh, Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2017). Cytochalasins from an Australian Marine Sediment-Derived Phomopsis sp. (CMB-M0042F): Acid-Mediated Intramolecular Cycloadditions Enhance Chemical Diversity. Journal of Organic Chemistry, 82 (18), 9704-9709. doi: 10.1021/acs.joc.7b01793
Microbiome-mediated biotransformation of cane toad bufagenins
Kamalakkannan, Venkatanambi, Salim, Angela A. and Capon, Robert J. (2017). Microbiome-mediated biotransformation of cane toad bufagenins. Journal of Natural Products, 80 (7), 2012-2017. doi: 10.1021/acs.jnatprod.7b00134
Shang, Zhuo, Salim, Angela A. and Capon, Robert J. (2017). Chaunopyran A: co-cultivation of marine mollusk-derived fungi activates a rare class of 2-alkenyl-tetrahydropyran. Journal of Natural Products, 80 (4), 1167-1172. doi: 10.1021/acs.jnatprod.7b00144
Quezada, Michelle, Shang, Zhuo, Kalansuriya, Pabasara, Salim, Angela A., Lacey, Ernest and Capon, Robert J. (2017). Waspergillamide A, a Nitro depsi-Tetrapeptide Diketopiperazine from an Australian Mud Dauber Wasp-Associated Aspergillus sp. (CMB-W031). Journal of Natural Products, 80 (4), 1192-1195. doi: 10.1021/acs.jnatprod.6b01062
Dewapriya, Pradeep, Prasad, Pritesh, Damodar, Rakesh, Salim, Angela A. and Capon, Robert J. (2017). Talarolide A, a cyclic heptapeptide hydroxamate from an Australian marine tunicate-associated fungus, Talaromyces sp. (CMB-TU011). Organic Letters, 19 (8), 2046-2049. doi: 10.1021/acs.orglett.7b00638
Small-molecule inhibitors of the SOX18 transcription factor
Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril A. B., Holmes, Kelly, Salim, Angela A., Mamidyala, Sreeman, Butler, Mark S., Robinson, Ashley S., Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L., Hogan, Benjamin M., De Val, Sarah, Capon, Robert J., Carroll, Jason S., Bailey, Timothy L., Koopman, Peter, Jauch, Ralf, Smyth, Mark J., Cooper, Matthew A., Gambin, Yann and Francois, Mathias (2017). Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 6 e21221. doi: 10.7554/eLife.21221
Cho, Kwang-Jin, Casteel, Darren E., Prakash, Priyanka, Tan, Lingxiao, van der Hoeven, Dharini, Angela Salim, Kim, Choel, Capon, Robert J., Lacey, Ernest, Cunha, Shane R., Gorfe, Alemayehu A. and Hancock, John F. (2016). AMPK and endothelial nitric oxide synthase signaling regulates K-Ras plasma membrane interactions via cyclic GMP-dependent protein kinase 2. Molecular and Cellular Biology, 36 (24), 3086-3099. doi: 10.1128/MCB.00365-16
Shang, Zhuo, Khalil, Zeinab, Li, Li, Salim, Angela A., Quezada, Michelle, Kalansuriya, Pabasara and Capon, Robert J. (2016). Roseopurpurins: chemical diversity enhanced by convergent biosynthesis and forward and reverse Michael additions. Organic Letters, 18 (17), 4340-4343. doi: 10.1021/acs.orglett.6b02099
Fungal biotransformation of tetracycline antibiotics
Shang, Zhuo, Salim, Angela A., Khalil, Zeinab, Bernhardt, Paul V. and Capon, Robert J. (2016). Fungal biotransformation of tetracycline antibiotics. Journal of Organic Chemistry, 81 (15), 6186-6194. doi: 10.1021/acs.joc.6b01272
C3 and 2D C3 Marfey’s methods for amino acid analysis in natural products
Vijayasarathy, Soumini, Prasad, Pritesh, Fremlin, Leith J., Ratnayake, Ranjala, Salim, Angela A., Khalil, Zeinab and Capon, Robert J. (2016). C3 and 2D C3 Marfey’s methods for amino acid analysis in natural products. Journal of Natural Products, 79 (2), 421-427. doi: 10.1021/acs.jnatprod.5b01125
Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold
Shang, Zhuo, Salim, Angela A., Khalil, Zeinab, Quezada, Michelle, Bernhardt, Paul V. and Capon, Robert J. (2015). Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold. Journal of Organic Chemistry, 80 (24), 12501-12508. doi: 10.1021/acs.joc.5b02367
Oligomycins as inhibitors of K-Ras plasma membrane localisation
Salim, A. A., Tan, L., Huang, X. C., Cho, K. J., Lacey, E., Hancock, J. F. and Capon, R. J. (2015). Oligomycins as inhibitors of K-Ras plasma membrane localisation. Organic and Biomolecular Chemistry, 14 (2), 711-715. doi: 10.1039/c5ob02020d
Shang, Zhuo, Li, Li, Esposito, Breno P., Salim, Angela A., Khalil, Zeinab G., Quezada, Michelle, Bernhardt, Paul V. and Capon, Robert J. (2015). New PKS-NRPS tetramic acids and pyridinone from an Australian marine-derived fungus, Chaunopycnis sp.. Organic and Biomolecular Chemistry, 13 (28), 7795-7802. doi: 10.1039/c5ob01058f
Khalil, Zeinab G., Raju, Ritesh, Piggott, Andrew M., Salim, Angela A., Blumenthal, Antje and Capon, Robert J. (2015). Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian marine-derived Streptomyces sp.. Journal of Natural Products, 78 (4), 949-952. doi: 10.1021/acs.jnatprod.5b00095
Farrugia, Michelle, Trotter, Nicholas, Vijayasarathy, Soumini, Salim, Angele A., Khalil, Zeinab G., Lacey, Ernest and Capon, Robert J. (2014). Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.. Tetrahedron Letters, 55 (43), 5902-5904. doi: 10.1016/j.tetlet.2014.08.116
Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras
Salim, Angela A., Cho, Kwang-Jin, Tan, Lingxiao, Quezada, Michelle, Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014). Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras. Organic Letters, 16 (19), 5036-5039. doi: 10.1021/ol502376e
Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces
Khalil, Zeinab G., Salim, Angela A., Lacey, Ernest, Blumenthal, Antje and Capon, Robert J. (2014). Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces. Organic Letters, 16 (19), 5120-5123. doi: 10.1021/ol502472c
Rare Streptomyces sp. polyketides as modulators of K-Ras localisation
Salim, Angela A., Xiao, Xue, Cho, Kwang-Jin, Piggott, Andrew M., Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014). Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Organic and Biomolecular Chemistry, 12 (27), 4872-4878. doi: 10.1039/c4ob00745j
Huang, Xiao-Cong, Xiao, Xue, Zhang, Yun-Kai, Talele, Tanaji T., Salim, Angela A., Chen, Zhe-Sheng and Capon, Robert J. (2014). Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells. Marine Drugs, 12 (7), 3818-3837. doi: 10.3390/md12073818
Huang, Xiao-cong, Sun, Yue-Li, Salim, Angela A., Chen, Zhe-Sheng and Capon, Robert J. (2013). Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Biochemical Pharmacology, 85 (9), 1257-1268. doi: 10.1016/j.bcp.2013.02.005
Standish, Alistair J., Salim, Angela A., Capon, Robert J. and Morona, Renato (2013). Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target. Biochemical and Biophysical Research Communications, 430 (1), 167-172. doi: 10.1016/j.bbrc.2012.11.049
Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins
Cho, Kwang-jin, Park, Jin-Hee, Piggott, Andrew M., Salim, Angela A., Gorfe, Alemaheyu A., Parton, Robert G., Capon, Robert J., Lacey, Ernest and Hancock, John F. (2012). Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. Journal of Biological Chemistry, 287 (52), 43573-43584. doi: 10.1074/jbc.M112.424457
Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2012). Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.. Tetrahedron, 68 (47), 9802-9807. doi: 10.1016/j.tet.2012.09.008
Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina)
Crossland, Michael R., Haramura, Takashi, Salim, Angela A., Capon, Robert J. and Shine, Richard (2012). Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina). Proceedings of the Royal Society B-Biological Sciences, 279 (1742), 3436-3442. doi: 10.1098/rspb.2012.0821
Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production
Standish, Alistair J., Salim, Angela A., Zhang, Hua, Capon, Robert J. and Morona, Renato (2012). Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production. Plos One, 7 (5) e36312, e36312.1-e36312.8. doi: 10.1371/journal.pone.0036312
Rae, James, Fontaine, Frank, Salim, Angela A., Lo, Harriet P., Capon, Robert J., Parton, Robert G. and Martin, Sally (2011). High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids. PLoS One, 6 (8) e22868, e22868.1-e22868.13. doi: 10.1371/journal.pone.0022868
Salim, Angela A., Rae, James, Fontaine, Frank, Conte, Melissa M., Khalil, Zeinab, Martin, Sally, Parton, Robert G. and Capon, Robert J. (2010). Heterofibrins: Inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp.. Organic and Biomolecular Chemistry, 8 (14), 3188-3194. doi: 10.1039/c003840g
New oxygenated diterpenes from an Australian nudibranch of the genus Chromodoris
Yong, Ken W. L., Salim, Angela A. and Garson, Mary J. (2008). New oxygenated diterpenes from an Australian nudibranch of the genus Chromodoris. Tetrahedron, 2008 (64), 6733-6738. doi: 10.1016/j.tet.2008.05.008
Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)
Tomosaka, Hideyuki, Chin, Young-Won, Salim, Angela A., Keller, William J., Chai, Heebyung and Kinghorn, A. Douglas (2008). Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry). Phytotherapy Research, 22 (7), 979-981. doi: 10.1002/ptr.2443
Biotransformation of mefenamic acid by cell suspension cultures of Solanum mammosum
Surodjo, S., Salim, A. ., Suciati, Syahrani, A., Indrayanto, G. and Garson, M.J. (2008). Biotransformation of mefenamic acid by cell suspension cultures of Solanum mammosum. Natural Product Communications, 3 (2), 257-262. doi: 10.1177/1934578x0800300231
Chin, Young-Won, Salim, Angela A., Su, Bao-Ning, Mi, Qiuwen, Chai, Hee-Byung, Riswan, Soedarsono, Kardono, Leonardus B. S., Ruskandi, Agus, Farnsworth, Norman R., Swanson, Steven M. and Kinghorn, A. Douglas (2008). Potential anticancer activity of naturally occurring and semi-synthetic derivatives of aculeatins A and B from Amomum aculeatumatum. Journal of Natural Products, 71 (3), 390-395. doi: 10.1021/np070584j
Constituents of the leaves and stem bark of Aglaia foveolata
Salim, Angela A., Chai, Hee-Byung, Rachman, Ismail, Riswan, Soedarsono, Kardono, Leonardus B.S., Farnsworth, Norman R., Carcache-Blanco, Esperanza J. and Kinghorn, A. Douglas (2007). Constituents of the leaves and stem bark of Aglaia foveolata. Tetrahedron, 63 (33), 7926-7934. doi: 10.1016/j.tet.2007.05.074
Dioxadispiroketal compounds and a potential acyclic precursor from Amomum aculeatum
Salim, Angela A., Sua, Bao-Ning, Chaia, Hee-Byung, Riswanb, Soedarsono, Kardonoc, Leonardus B. S., Ruskandib, Agus, Farnsworthd, Norman R., Swansond, Steven M. and Kinghorna, A. Douglas (2007). Dioxadispiroketal compounds and a potential acyclic precursor from Amomum aculeatum. Tetrahedron letters, 48 (10), 1849-1853. doi: 10.1016/j.tetlet.2007.01.017
Ponapensin, a cyclopenta(bc)benzopyran with potent NF-kB inhibitory activity from Aglaia ponapensis
Salim, Angela A., Pawlus, Alison D., Chai, Hee-Byung, Farnsworth, Norman R., Kinghorn, A. Douglas and Carcache-Blanco, Esperanza J. (2007). Ponapensin, a cyclopenta(bc)benzopyran with potent NF-kB inhibitory activity from Aglaia ponapensis. Bioorganic & Medicinal Chemistry Letters, 17 (1), 109-112. doi: 10.1016/j.bmcl.2006.09.084
Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy
Kim, Soyoung, Salim, Angela A., Swanson, Steven M. and Douglas Kinghorn, A. (2006). Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anti-Cancer Agents in Medicinal Chemistry, 6 (4), 319-345. doi: 10.2174/187152006777698123
New Indole Alkaloids from the bark of Alstonia scholaris
Salim, Angela A., Garson, Mary J. and Craik, David J. (2004). New Indole Alkaloids from the bark of Alstonia scholaris. Journal of Natural Products, 67 (9), 1591-1594. doi: 10.1021/np0498612
New alkaloids from Pandanus amaryllifolius
Salim, Angela A., Garson, Mary J. and Craik, David J. (2004). New alkaloids from Pandanus amaryllifolius. Journal of Natural Products, 67 (1), 54-57. doi: 10.1021/np0303310
New indole alkaloids from the roots of Ochrosia acuminata
Salim, A. A., Garson, M. J. and Craik, D. J. (2004). New indole alkaloids from the roots of Ochrosia acuminata. Journal of Natural Products, 67 (10), 1719-1721. doi: 10.1021/np049812p
Structure and function of plant toxins (with emphasis on cystine knot toxins)
Craik, D. J., Daly, N. L., Plan, M. R., Salim, A. A. and Sando, L. (2002). Structure and function of plant toxins (with emphasis on cystine knot toxins). Journal of Toxicology-toxin Reviews, 21 (3), 229-271. doi: 10.1081/TXR-120014405
Giri, R., Shamsunnahar, K., Salim, A., Capon, R., Morrison, M., Cuiv, P. O. and Begun, J. (2020). Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel disease. 15th Congress of ECCO, Vienna, Austria, 12-15 February 2020. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjz203.035
Dewapriya, Pradeep, Khalil, Zeinab G., Prasad, Pritesh, Salim, Angela A., Morales, Pablo C., Marcellin, Esteban and Capon, Robert J. (2018). Talaropeptides A–D: Structure and biosynthesis of extensively N-methylated linear peptides from an Australian marine tunicate-derived Talaromyces sp.. American Society of Pharmacognosy Annual Meeting ASP 2018, Lexington, KY United States, 21-25 July 2018.
Dewapriya, Pradeep, Prasad, Pritesh, Damodar, Rakesh, Salim, Angela A. and Capon, Robert J. (2017). Talarolide A, a cyclic heptapeptide hydroxamate from an Australian marine tunicate-associated fungus, Talaromyces sp.. 2nd International Conference of Marine Fungal Natural Products, Kiel, Germany, 27-29 June 2017.
Viridicatumtoxins: Exploring structural diversity and antibiotic properties
Shang, Z., Salim, A. A., Khalil, Z. G., Quezada, M., Bernhardt, P. V. and Capon, R. J. (2015). Viridicatumtoxins: Exploring structural diversity and antibiotic properties. Annual Meeting of the American-Society-of-Pharmacognosy, Copper Mountain, CO, United States, 25-29 July 2015. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-0035-1556338
Chemical studies on Indonesian medicinal plants
Garson, M.J., Salim, A.A., . Rudiyansyah, Suciati and Ross, B.P. (2008). Chemical studies on Indonesian medicinal plants. International Organization for Chemical Sciences in Development Meeting, Botswana, February, 2008.
Lucas, David M., Edwards, Ryan B., De lay, Michael D., West, Derek A., Lozanski, Gerard, Johnson, Amy J., Salim, Angela A., Lin, Thomas S., Byrd, John C., Kinghorn, A. Douglas and Grever, Michael R. (2007). The plant-derived agent silvestrol has B-Cell selective activity in vitro in chronic lymphocytic leukemia patient cells and in vivo in the Tcl-1 mouse model of CLL. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA United States, 8-11 December 2007. Washington, DC United States: American Society of Hematology.
AGFD 132-Antioxidants from Berberis vulgaris (Barberry)
Tomosaka, Hideyuki, Chai, Heebyung, Chin, Young-Won, Salim, Angela A., Keller, William J. and Kinghorn, A. Douglas (2007). AGFD 132-Antioxidants from Berberis vulgaris (Barberry). WASHINGTON: AMER CHEMICAL SOC.
Lucas, David M., Edwards, Ryan B., De Lay, Michael D., West, Derek A., Lozanski, Gerard, Johnson, Amy J., Salim, Angela A., Lin, Thomas S., Byrd, John C., Kinghorn, A. Douglas and Grever, Michael R. (2007). The Plant-Derived Agent Silvestrol Has B-Cell Selective Activity In Vitro in Chronic Lymphocytic Leukemia Patient Cells and In Vivo in the Tcl-1 Mouse Model of CLL Blood (ASH Annual Meeting Abstracts) 2007 110: Abstract 3123. 49th ASH Annual Meeting: Blood (ASH Annual Meeting Abstracts), Georgia World Congress Center, Atlanta, Georgia, 8-11 December 2007. American Society of Hematology.
Chemical diversity and Indonesian medicinal plants
Garson, M J, Rudiyansyah, .., Salim, A. and Craik, D J (2006). Chemical diversity and Indonesian medicinal plants. 21st Philippino Chemical Congress, Davao, 4-7 April, 2006.
Novel bioactive alkaloids from Ochrosia acuminata and Alstonia scholaris
Salim, A., Garson, M. J. and Craik, D. J. (2004). Novel bioactive alkaloids from Ochrosia acuminata and Alstonia scholaris. SimNasKBA-2004, Bandung, Dec, 2004.
Novel bioactive alkaloids from Ochrosia acuminate and Alstonia scholaris
Salim, A., Garson, M. J. and Craik, D. J. (2004). Novel bioactive alkaloids from Ochrosia acuminate and Alstonia scholaris. American Society of Pharmacognosy Annual Meeting, Phoenix, July, 2004.
Novel bioalkaloids from Ochrosia acuminate and Alstonia scholaris
Salim, A., Garson, M. J. and Craik, D. J. (2004). Novel bioalkaloids from Ochrosia acuminate and Alstonia scholaris. ANZMAG 2004, Adelaide, 15-20 Feb, 2004.
Novel bioactive alkaloids from Alstonia scholaris bark
Salim, A., Garson, M. J. and Craik, D. J. (2003). Novel bioactive alkaloids from Alstonia scholaris bark. BBOCS: Brisbane Biological and Organic Chemistry Symposium 2003, Brisbane, 28 November 2003.
Novel bioactive alkaloids from Ochrosia acuminata root
Salim, A., Garson, M. J. and Craik, D. J. (2003). Novel bioactive alkaloids from Ochrosia acuminata root. BBOCS: Brisbane Biological and Organic Chemistry Symposium 2003, Brisbane, 28 November 2003.
Novel bioactive alkaloids from Ochrosia acuminata root
Salim, A., Garson, M. J. and Craik, D. J. (2003). Novel bioactive alkaloids from Ochrosia acuminata root. XI Asian Symposium on Medicinal Plants, Spices and Other Natural Products, Kunming, China, 26-30 October, 2003.
Novel bioactive alkaloids from Ochrosia acuminata root
Salim, A., Garson, M. J. and Craik, D. J. (2003). Novel bioactive alkaloids from Ochrosia acuminata root. RACI National Organic Chemistry Conference, Lorne, Victoria, July, 2003.
Novel Bioactive alkaloids from Pandanus amaryllifolius from West Timor
Salim, A., Garson, M. J. and Craik, D. J. (2002). Novel Bioactive alkaloids from Pandanus amaryllifolius from West Timor. 23rd International Conference on Natural Products, Italy, July, 2002.
Novel Bioactive alkaloids from a Pandanus amaryllifolius from West Timor
Salim, A., Garson, M. J. and Craik, D. J. (2002). Novel Bioactive alkaloids from a Pandanus amaryllifolius from West Timor. Brisbane Biological & Organic Chemistry Symposium, Brisbane, November, 2002.
Australian marine microbes as a source of next generation antiparasitics
(2022–2025) Marine Bioproducts Cooperative Research Centre
NOMETA MICROBIAL BIODISCOVERY: ACCESSING NEW CHEMICAL SPACE TO DISCOVER NEW ANTIBIOTIC CLASSES
Doctor Philosophy — Associate Advisor
Other advisors:
Medicinal chemistry of new Nature-inspired treatments for Inflammatory Bowel Disease (IBD)
Doctor Philosophy — Associate Advisor
Other advisors:
The discovery of new antibiotics to combat drug resistance
Doctor Philosophy — Associate Advisor
Other advisors:
Understanding the host-microbe interaction to modulate immune response in IBD
Doctor Philosophy — Associate Advisor
Other advisors:
Global Natural Product Social Molecular Network Guided Australian Microbial Biodiscovery
(2022) Doctor Philosophy — Associate Advisor
Other advisors:
Microbial Biodiscovery: Integrated technologies to explore chemical potential of Australian microbes
(2022) Doctor Philosophy — Associate Advisor
Other advisors:
Applying Molecular Networking to Natural Products Chemistry
(2021) Doctor Philosophy — Associate Advisor
Other advisors:
Marine Biodiversity: Exploring Bioactive Chemical Space
(2017) Doctor Philosophy — Associate Advisor
Other advisors:
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
Unveiling the Chemical Diversity of Marine Intertidal Fungal Communities
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
(2013) Doctor Philosophy — Associate Advisor
Other advisors: